MAB1241
antibody from R&D Systems
Targeting: TNFSF13B
BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- MAB1241 - Provider product page
- Provider
- R&D Systems
- Product name
- Human BAFF/BLyS/TNFSF13B Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human BAFF/BLyS/TNFSF13B in direct ELISAs and Western blots. In Western blots, approximately 5% cross-reactivity with recombinant human (rh) TL1A/TNSF15 is observed and no cross-reactivity with rhAPRIL, rhTNF-alpha , rhFas Ligand, rhGITR Ligand, rhLIGHT, rhTRAIL, rhTRANCE, or rhTWEAK is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
Q9Y275
- Isotype
- IgG
- Antibody clone number
- 137314
- Vial size
- 500 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references The role of the BAFF/APRIL system in the T cell-independent specific response to blood stage Plasmodium falciparum hemozoin.
Macrophages induce differentiation of plasma cells through CXCL10/IP-10.
Aberrant expression of BAFF by B lymphocytes infiltrating the salivary glands of patients with primary Sjögren's syndrome.
Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt's lymphoma.
Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt's lymphoma.
Dechkajorn W, Benjathummarak S, Kumsiri R, Maneerat Y
Cytokine 2018 Nov;111:445-453
Cytokine 2018 Nov;111:445-453
Macrophages induce differentiation of plasma cells through CXCL10/IP-10.
Xu W, Joo H, Clayton S, Dullaers M, Herve MC, Blankenship D, De La Morena MT, Balderas R, Picard C, Casanova JL, Pascual V, Oh S, Banchereau J
The Journal of experimental medicine 2012 Sep 24;209(10):1813-23, S1-2
The Journal of experimental medicine 2012 Sep 24;209(10):1813-23, S1-2
Aberrant expression of BAFF by B lymphocytes infiltrating the salivary glands of patients with primary Sjögren's syndrome.
Daridon C, Devauchelle V, Hutin P, Le Berre R, Martins-Carvalho C, Bendaoud B, Dueymes M, Saraux A, Youinou P, Pers JO
Arthritis and rheumatism 2007 Apr;56(4):1134-44
Arthritis and rheumatism 2007 Apr;56(4):1134-44
Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt's lymphoma.
Ogden CA, Pound JD, Batth BK, Owens S, Johannessen I, Wood K, Gregory CD
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 1;174(5):3015-23
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 1;174(5):3015-23
Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt's lymphoma.
Ogden CA, Pound JD, Batth BK, Owens S, Johannessen I, Wood K, Gregory CD
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 1;174(5):3015-23
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 1;174(5):3015-23
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