13797-1-AP

antibody from Proteintech Group

Targeting: PTX3 TNFAIP5, TSG-14

Provider product page for 13797-1-AP

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Immunocytochemistry

Antibody data

Antibody Data
Antigen structure
References [25]
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Validations
Western blot [1]

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Product number: 13797-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#13797-1-AP, RRID:AB_2165302
Product name: Pentraxin 3 antibody
Antibody type: Polyclonal
Description: KD/KO validated Pentraxin 3 antibody (Cat. #13797-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

PTX3 protein structure - 13797-1-AP shown in red.

Submitted references Pentraxin 3 exacerbates psoriasiform dermatitis through regulation of macrophage polarization.

Liu J, Qiu C, Zhou Z, Li J, Zhen Y, Wang R, Zhuang Y, Zhang F
International immunopharmacology 2024 Mar 30;130:111805

Synergistic effects of tetramethylpyrazine and astragaloside IV on spinal cord injury via alteration of astrocyte A1/A2 polarization through the Sirt1-NF-κB pathway.

Rao Y, Li J, Qiao R, Luo J, Liu Y
International immunopharmacology 2024 Apr 20;131:111686

Pentraxin 3 plays a key role in tubular cell senescence and renal fibrosis through inducing β-catenin signaling.

Luo P, Zhang H, Liang Y, Li X, Wen Z, Xia C, Lan X, Yang Y, Xiong Y, Huang J, Ling X, Zhou S, Miao J, Shen W, Hou FF, Liu Y, Zhou L, Liang M
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166807

RNA m(6)A methylation modulates airway inflammation in allergic asthma via PTX3-dependent macrophage homeostasis.

Han X, Liu L, Huang S, Xiao W, Gao Y, Zhou W, Zhang C, Zheng H, Yang L, Xie X, Liang Q, Tu Z, Yu H, Fu J, Wang L, Zhang X, Qian L, Zhou Y
Nature communications 2023 Nov 13;14(1):7328

NeuroD1 administration ameliorated neuroinflammation and boosted neurogenesis in a mouse model of subarachnoid hemorrhage.

Chen P, Liu XY, Lin MH, Li YX, Kang DZ, Ye ZC, Lin QS
Journal of neuroinflammation 2023 Nov 12;20(1):261

Urchin-like ceria nanoparticles for enhanced gene therapy of osteoarthritis.

Chen H, Ye T, Hu F, Chen K, Li B, Qiu M, Chen Z, Sun Y, Ye W, Wang H, Ni D, Guo L
Science advances 2023 Jun 16;9(24):eadf0988

Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area.

Xu Y, Zhu ZH, Xu X, Sun HT, Zheng HM, Zhang JL, Wang HH, Fang JW, Liu YZ, Huang LL, Song ZW, Liu JB
Molecular neurobiology 2023 Aug;60(8):4502-4516

TNFAIP6 Promotes Gastric Carcinoma Cell Invasion via Upregulating PTX3 and Activating the Wnt/β-Catenin Signaling Pathway.

Cui H, Zhang L, Chen B, Zhang F, Xu H, Ma G, Cao L, Wang M
Contrast media & molecular imaging 2022;2022:5697034

PTX3 mediates the infiltration, migration, and inflammation-resolving-polarization of macrophages in glioblastoma.

Zhang H, Wang Y, Zhao Y, Liu T, Wang Z, Zhang N, Dai Z, Wu W, Cao H, Feng S, Zhang L, Cheng Q, Liu Z
CNS neuroscience & therapeutics 2022 Nov;28(11):1748-1766

Pentraxin 3 regulated by miR-224-5p modulates macrophage reprogramming and exacerbates osteoarthritis associated synovitis by targeting CD32.

Yin J, Zeng H, Fan K, Xie H, Shao Y, Lu Y, Zhu J, Yao Z, Liu L, Zhang H, Luo B, Wang X, Zeng C, Bai X, Zhang H, Cai D
Cell death & disease 2022 Jun 24;13(6):567

PTX3 alleviates hard metal-induced acute lung injury through potentiating efferocytosis.

Yan W, Ma D, Liu Y, Sun W, Cheng D, Li G, Zhou S, Wang Y, Wang H, Ni C
Ecotoxicology and environmental safety 2022 Jan 15;230:113139

Sphingosine kinase 1 promotes growth of glioblastoma by increasing inflammation mediated by the NF-κB /IL-6/STAT3 and JNK/PTX3 pathways.

Li W, Cai H, Ren L, Yang Y, Yang H, Liu J, Li S, Zhang Y, Zheng X, Tan W, Du G, Wang J
Acta pharmaceutica Sinica. B 2022 Dec;12(12):4390-4406

Melatonin Maintains Homeostasis and Potentiates the Anti-inflammatory Response in Staphylococcus aureus-Induced Mastitis through microRNA-16b/YAP1.

Chen Z, Wang K, Guo J, Zhou J, Loor JJ, Yang Z, Yang Y
Journal of agricultural and food chemistry 2022 Dec 7;70(48):15255-15270

Pentraxin-3 inhibits milky spots metastasis of gastric cancer by inhibiting M2 macrophage polarization.

Cui X, Qin T, Zhao Z, Yang G, Sanches JGP, Zhang Q, Fan S, Cao L, Hu X
Journal of Cancer 2021;12(15):4686-4697

Pentraxin 3 Promotes Glioblastoma Progression by Negative Regulating Cells Autophagy.

Wang Z, Wang X, Zhang N, Zhang H, Dai Z, Zhang M, Feng S, Cheng Q
Frontiers in cell and developmental biology 2020;8:795

Cytokine TNF-α promotes invasion and metastasis of gastric cancer by down-regulating Pentraxin3.

Cui X, Zhang H, Cao A, Cao L, Hu X
Journal of Cancer 2020;11(7):1800-1807

SH3RF3 promotes breast cancer stem-like properties via JNK activation and PTX3 upregulation.

Zhang P, Liu Y, Lian C, Cao X, Wang Y, Li X, Cong M, Tian P, Zhang X, Wei G, Liu T, Hu G
Nature communications 2020 May 19;11(1):2487

Silencing of PTX3 alleviates LPS-induced inflammatory pain by regulating TLR4/NF-κB signaling pathway in mice.

Qi S, Zhao F, Li Z, Liang F, Yu S
Bioscience reports 2020 Feb 28;40(2)

Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.

Kampo S, Ahmmed B, Zhou T, Owusu L, Anabah TW, Doudou NR, Kuugbee ED, Cui Y, Lu Z, Yan Q, Wen QP
Frontiers in oncology 2019;9:21

Investigation of the Mechanism Underlying Calcium Dobesilate-Mediated Improvement of Endothelial Dysfunction and Inflammation Caused by High Glucose.

Zhou Y, Qi C, Li S, Shao X, Ni Z
Mediators of inflammation 2019;2019:9893682

Tunicamycin enhances the suppressive effects of cisplatin on lung cancer growth through PTX3 glycosylation via AKT/NF-κB signaling pathway.

Ahmmed B, Khan MN, Nisar MA, Kampo S, Zheng Q, Li Y, Yan Q
International journal of oncology 2019 Feb;54(2):431-442

Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling.

Kugeratski FG, Atkinson SJ, Neilson LJ, Lilla S, Knight JRP, Serneels J, Juin A, Ismail S, Bryant DM, Markert EK, Machesky LM, Mazzone M, Sansom OJ, Zanivan S
Science signaling 2019 Feb 5;12(567)

The Versican G1 Fragment and Serum-Derived Hyaluronan-Associated Proteins Interact and Form a Complex in Granulation Tissue of Pressure Ulcers.

Murasawa Y, Nakamura H, Watanabe K, Kanoh H, Koyama E, Fujii S, Kimata K, Zako M, Yoneda M, Isogai Z
The American journal of pathology 2018 Feb;188(2):432-449

Pathological Features of Staphylococcus aureus Induced Mastitis in Dairy Cows and Isobaric-Tags-for-Relative-and-Absolute-Quantitation Proteomic Analyses.

Chen Z, Xia H, Shen H, Xu X, Arbab AAI, Li M, Zhang H, Mao Y, Yang Z
Journal of agricultural and food chemistry 2018 Apr 18;66(15):3880-3890

Identification of colonic fibroblast secretomes reveals secretory factors regulating colon cancer cell proliferation.

Chen SX, Xu XE, Wang XQ, Cui SJ, Xu LL, Jiang YH, Zhang Y, Yan HB, Zhang Q, Qiao J, Yang PY, Liu F
Journal of proteomics 2014 Oct 14;110:155-71

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The Pentraxin 3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Pentraxin 3. This antibody recognizes human,mouse,rat antigen. The Pentraxin 3 antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 13797-1-AP.pdf

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