Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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- Product number
- ALX-804-464-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-804-464-C100, RRID:AB_2052427
- Product name
- PTX3 monoclonal antibody (MNB4)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full length protein
- Reactivity
- Human, Rat
- Host
- Rat
- Isotype
- IgG
- Antibody clone number
- MNB4
- Vial size
- 100 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles.
Submitted references Atorvastatin reduces long pentraxin 3 expression in vascular cells by inhibiting protein geranylgeranylation.
Inflammation and thrombosis in essential thrombocythemia and polycythemia vera: different role of C-reactive protein and pentraxin 3.
Endogenous PTX3 translocates at the membrane of late apoptotic human neutrophils and is involved in their engulfment by macrophages.
Pentraxin 3 is elevated in haemodialysis patients and is associated with cardiovascular disease.
The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps.
The long pentraxin PTX3 is synthesized in IgA glomerulonephritis and activates mesangial cells.
Production of the long pentraxin PTX3 in advanced atherosclerotic plaques.
PTX3, A prototypical long pentraxin, is an early indicator of acute myocardial infarction in humans.
Multimer formation and ligand recognition by the long pentraxin PTX3. Similarities and differences with the short pentraxins C-reactive protein and serum amyloid P component.
Baetta R, Lento S, Ghilardi S, Barbati E, Corsini A, Tremoli E, Banfi C
Vascular pharmacology 2015 Apr-Jun;67-69:38-47
Vascular pharmacology 2015 Apr-Jun;67-69:38-47
Inflammation and thrombosis in essential thrombocythemia and polycythemia vera: different role of C-reactive protein and pentraxin 3.
Barbui T, Carobbio A, Finazzi G, Vannucchi AM, Barosi G, Antonioli E, Guglielmelli P, Pancrazzi A, Salmoiraghi S, Zilio P, Ottomano C, Marchioli R, Cuccovillo I, Bottazzi B, Mantovani A, Rambaldi A, AGIMM and IIC Investigators
Haematologica 2011 Feb;96(2):315-8
Haematologica 2011 Feb;96(2):315-8
Endogenous PTX3 translocates at the membrane of late apoptotic human neutrophils and is involved in their engulfment by macrophages.
Jaillon S, Jeannin P, Hamon Y, Frémaux I, Doni A, Bottazzi B, Blanchard S, Subra JF, Chevailler A, Mantovani A, Delneste Y
Cell death and differentiation 2009 Mar;16(3):465-74
Cell death and differentiation 2009 Mar;16(3):465-74
Pentraxin 3 is elevated in haemodialysis patients and is associated with cardiovascular disease.
Boehme M, Kaehne F, Kuehne A, Bernhardt W, Schröder M, Pommer W, Fischer C, Becker H, Müller C, Schindler R
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007 Aug;22(8):2224-9
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007 Aug;22(8):2224-9
The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps.
Jaillon S, Peri G, Delneste Y, Frémaux I, Doni A, Moalli F, Garlanda C, Romani L, Gascan H, Bellocchio S, Bozza S, Cassatella MA, Jeannin P, Mantovani A
The Journal of experimental medicine 2007 Apr 16;204(4):793-804
The Journal of experimental medicine 2007 Apr 16;204(4):793-804
The long pentraxin PTX3 is synthesized in IgA glomerulonephritis and activates mesangial cells.
Bussolati B, Peri G, Salvidio G, Verzola D, Mantovani A, Camussi G
Journal of immunology (Baltimore, Md. : 1950) 2003 Feb 1;170(3):1466-72
Journal of immunology (Baltimore, Md. : 1950) 2003 Feb 1;170(3):1466-72
Production of the long pentraxin PTX3 in advanced atherosclerotic plaques.
Rolph MS, Zimmer S, Bottazzi B, Garlanda C, Mantovani A, Hansson GK
Arteriosclerosis, thrombosis, and vascular biology 2002 May 1;22(5):e10-4
Arteriosclerosis, thrombosis, and vascular biology 2002 May 1;22(5):e10-4
PTX3, A prototypical long pentraxin, is an early indicator of acute myocardial infarction in humans.
Peri G, Introna M, Corradi D, Iacuitti G, Signorini S, Avanzini F, Pizzetti F, Maggioni AP, Moccetti T, Metra M, Cas LD, Ghezzi P, Sipe JD, Re G, Olivetti G, Mantovani A, Latini R
Circulation 2000 Aug 8;102(6):636-41
Circulation 2000 Aug 8;102(6):636-41
Multimer formation and ligand recognition by the long pentraxin PTX3. Similarities and differences with the short pentraxins C-reactive protein and serum amyloid P component.
Bottazzi B, Vouret-Craviari V, Bastone A, De Gioia L, Matteucci C, Peri G, Spreafico F, Pausa M, D'Ettorre C, Gianazza E, Tagliabue A, Salmona M, Tedesco F, Introna M, Mantovani A
The Journal of biological chemistry 1997 Dec 26;272(52):32817-23
The Journal of biological chemistry 1997 Dec 26;272(52):32817-23
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Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Dendritic cells that phagocyte Aspergillus fumigatus stained with MAb to PTX3 (MNB4) (Prod. No. ALX-804-464).