M00777
antibody from Boster Biological Technology
Targeting: NLRP1
CARD7, CLR17.1, DEFCAP, DKFZp586O1822, KIAA0926, NAC, NALP1, SLEV1, VAMAS1
Antibody data
- Antibody Data
- Antigen structure
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- Product number
- M00777 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-NLRP1/NALP1 Antibody (Monoclonal, Nalpy1-4)
- Antibody type
- Monoclonal
- Description
- Monoclonal, Nalpy1-4 antibody for NALP1/NLRP1 detection. Host: Mouse.Size: 100μg/vial. Tested applications: IP. Reactive species: Human. NALP1/NLRP1 information: Molecular Weight: 165866 MW; Subcellular Localization: Cytoplasm, cytosol . Cytoplasm . Inflammasome . Nucleus . Nucleocytoplasmic distribution in lymphoid organs (probably in T-cells) and in neurons. In epithelial cells, predominantly cytoplasmic; Tissue Specificity: Widely expressed (PubMed:11113115, PubMed:17164409). Abundantly expressed in primary immune cells (isoform 1 and isoform 2), including in neutrophils, monocytes/macrophages, dendritic cells (mostly Langerhans cells), and B- and T-lymphocytes (at protein level) (PubMed:15285719, PubMed:17164409). Strongly expressed in epithelial cells lining the glandular epithelium, such as that of the gastrointestinal tract (stomach, small intestine, colon), the respiratory tract (trachea and bronchi), and the endometrial and endocervical glands, gallbladder, prostate, and breast (at protein level). In testis, expressed in spermatogonia and primary spermatocytes, but not in Sertoli cells (at protein level). In the brain, expressed in neurons, in particular in pyramidal ones and in oligodendrocytes, but not detected in microglia (at protein level) (PubMed:17164409). Expressed in adult and fetal ocular tissues, including in adult and 24-week old fetal choroid, sclera, cornea, and optic nerve, as well as in adult retina and fetal retina/retinal pigment epithelium (PubMed:23349227).
- Reactivity
- Human
- Host
- Mouse
- Antibody clone number
- Nalpy1-4
- Vial size
- 100μg/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
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