NB100-56148
antibody from Novus Biologicals
Targeting: NLRP1
CARD7, CLR17.1, DEFCAP, DKFZp586O1822, KIAA0926, NAC, NALP1, SLEV1, VAMAS1
Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
Comment
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- Product number
- NB100-56148 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-56148, RRID:AB_838109
- Product name
- Rabbit Polyclonal NLRP1/NALP1 Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified. NALP1
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.05 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury.
Pronin A, Pham D, An W, Dvoriantchikova G, Reshetnikova G, Qiao J, Kozhekbaeva Z, Reiser AE, Slepak VZ, Shestopalov VI
Frontiers in molecular neuroscience 2019;12:36
Frontiers in molecular neuroscience 2019;12:36
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: NLRP1/NALP1 Antibody [NB100-56148] - Analysis of NLRP1/NALP1 in adult human tissue lysates using NLRP1 antibody at 1:2000. Full-length NLRP1 protein was detected at highest levels in kidney, brain and epidermis. A smaller band was detected in thymus, possibly representing a NLRP1/NALP1 breakdown product or alternatively spliced form. 293T/NALP1: positive control, 293T cells transiently transfected with full-length NLRP1.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: NLRP1/NALP1 Antibody [NB100-56148] - FFPE normal human tissue sections stained for NALP1 (CARD7/NAC) using NB100-56148 at 1:2000. (A) epidermis, (B) esophagus (C) uterine cervix, and (D) thymus. Hematoxylin-eosin counterstain. In A-C, NALP1 expression is associated with differentiation in stratified epithelial of the skin, esophagus, and cervix.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: NLRP1/NALP1 Antibody [NB100-56148] - FFPE human tissue sections stained for NALP1 (CARD7/NAC) using NB100-56148 at 1:2000. (A) bone marrow and (C) brain glioma core from a brain cancer microarray. (B) and (D) are higher magnifications of (A) and (C) respectively. Hemaxotylin-eosin counterstain.