Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 13321-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13321-1-AP, RRID:AB_2204641
- Product name
- TSG-6 antibody
- Antibody type
- Polyclonal
- Description
- TSG-6 antibody (Cat. #13321-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Efficacy and Potential Mechanisms of Yi-Ping Lin Circum-Knee Acupuncture in the Treatment of Knee Osteoarthritis.
N-glycosylation stabilized TNFAIP6 promotes ovarian cancer metastasis by activating the PI3K-AKT signaling pathway.
Renal protective effects of extracellular vesicle-encapsulated tumor necrosis factor-α-induced protein 6 derived from mesenchymal stem cells.
YAP1 Inhibition Induces Phenotype Switching of Cancer-Associated Fibroblasts to Tumor Suppressive in Prostate Cancer.
Tumor necrosis factor-stimulated gene-6 ameliorates early brain injury after subarachnoid hemorrhage by suppressing NLRC4 inflammasome-mediated astrocyte pyroptosis.
Identification and validation of up-regulated TNFAIP6 in osteoarthritis with type 2 diabetes mellitus.
Neutrophil infiltration associated genes on the prognosis and tumor immune microenvironment of lung adenocarcinoma.
TNFAIP6 Promotes Gastric Carcinoma Cell Invasion via Upregulating PTX3 and Activating the Wnt/β-Catenin Signaling Pathway.
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis via Suppression of STAT3 Activation.
Atheroprotective Effects of Tumor Necrosis Factor-Stimulated Gene-6.
Huang L, Deng X, Jin Y, Li J, Wu X, Xiong Y, Guo S, Yan S, Lu S, Chen D
Journal of pain research 2025;18:5891-5906
Journal of pain research 2025;18:5891-5906
N-glycosylation stabilized TNFAIP6 promotes ovarian cancer metastasis by activating the PI3K-AKT signaling pathway.
Liu X, Ji D, Wen Z, Tang Q, Chen Y
Cellular signalling 2025 Nov;135:112013
Cellular signalling 2025 Nov;135:112013
Renal protective effects of extracellular vesicle-encapsulated tumor necrosis factor-α-induced protein 6 derived from mesenchymal stem cells.
Morimoto K, Nakashima A, Ishiuchi N, Miyasako K, Tanaka Y, Sasaki K, Matsuda G, Maeda S, Miyaki S, Masaki T
Stem cells (Dayton, Ohio) 2025 May 15;43(5)
Stem cells (Dayton, Ohio) 2025 May 15;43(5)
YAP1 Inhibition Induces Phenotype Switching of Cancer-Associated Fibroblasts to Tumor Suppressive in Prostate Cancer.
Song H, Lu T, Han D, Zhang J, Gan L, Xu C, Liu S, Li P, Zhang K, Hu Z, Li H, Li Y, Zhao X, Zhang J, Xing N, Shi C, Wen W, Yang F, Qin W
Cancer research 2024 Nov 15;84(22):3728-3742
Cancer research 2024 Nov 15;84(22):3728-3742
Tumor necrosis factor-stimulated gene-6 ameliorates early brain injury after subarachnoid hemorrhage by suppressing NLRC4 inflammasome-mediated astrocyte pyroptosis.
Ding M, Jin L, Wei B, Cheng W, Liu W, Li X, Duan C
Neural regeneration research 2024 May;19(5):1064-1071
Neural regeneration research 2024 May;19(5):1064-1071
Identification and validation of up-regulated TNFAIP6 in osteoarthritis with type 2 diabetes mellitus.
Liu S, Chen H, Yang X, Wen Y, Chen L
Scientific reports 2024 Dec 28;14(1):31450
Scientific reports 2024 Dec 28;14(1):31450
Neutrophil infiltration associated genes on the prognosis and tumor immune microenvironment of lung adenocarcinoma.
Liu R, Zhu G, Sun Y, Li M, Hu Z, Cao P, Li X, Song Z, Chen J
Frontiers in immunology 2023;14:1304529
Frontiers in immunology 2023;14:1304529
TNFAIP6 Promotes Gastric Carcinoma Cell Invasion via Upregulating PTX3 and Activating the Wnt/β-Catenin Signaling Pathway.
Cui H, Zhang L, Chen B, Zhang F, Xu H, Ma G, Cao L, Wang M
Contrast media & molecular imaging 2022;2022:5697034
Contrast media & molecular imaging 2022;2022:5697034
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Tang B, Song M, Xie X, Le D, Tu Q, Wu X, Chen M
Neurochemical research 2021 Sep;46(9):2387-2402
Neurochemical research 2021 Sep;46(9):2387-2402
TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis via Suppression of STAT3 Activation.
Wan YM, Wu HM, Li YH, Xu ZY, Yang JH, Liu C, He YF, Wang MJ, Wu XN, Zhang Y
Frontiers in pharmacology 2020;11:10
Frontiers in pharmacology 2020;11:10
Atheroprotective Effects of Tumor Necrosis Factor-Stimulated Gene-6.
Watanabe R, Watanabe H, Takahashi Y, Kojima M, Konii H, Watanabe K, Shirai R, Sato K, Matsuyama TA, Ishibashi-Ueda H, Iso Y, Koba S, Kobayashi Y, Hirano T, Watanabe T
JACC. Basic to translational science 2016 Oct;1(6):494-509
JACC. Basic to translational science 2016 Oct;1(6):494-509
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The TSG-6 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TSG-6. This antibody recognizes human,mouse,rat antigen. The TSG-6 antibody has been validated for the following applications: ELISA, WB analysis.