orb131891

antibody from Biorbyt

Targeting: RIF1 FLJ10599, FLJ12870

Western blot (Data presented on provider website)

Antibody Data

Product number

orb131891

Provider

Biorbyt

Product name

RIF1 antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal to RIF1. Telomere-associated protein RIF1 shares homology with the yeast teleomere binding protein, Rap1 interacting factor 1. RIF1 localizes to aberrant telomeres and may be involved in DNA repair. RIF1 is required for checkpoint mediated arrest of cell cycle progression in response to DNA damage during S-phase (the intra-S-phase checkpoint). This checkpoint requires activation of at least 2 parallel pathways by the ATM kinase: one involves the MRN (MRE11A-RAD50-NBS1) complex, while the second requires CHEK2. RIF1 seems to act independently of both pathways. RIF1 seems to play no role in either the G1/S or G2/M DNA damage checkpoints.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Vial size

100 ul

Concentration

100 μg/ml BSA

Storage

-20°C