Antibody data
- Antibody Data
- Antigen structure
- References [26]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 23408-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- RANKL antibody
- Antibody type
- Polyclonal
- Description
- RANKL antibody (Cat. #23408-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Saponins from Nigella glandulifera seeds attenuate collagen-induced rheumatoid arthritis in rats via the OPG/RANKL/NF-κB and Ang/Tie-2 pathways.
Total Saponins from Nigella glandulifera Seeds Ameliorate Adjuvant-Induced Rheumatoid Arthritis in Rats by Inhibition of an Inflammatory Response and Bone Erosion.
Tomatidine Suppresses the Destructive Behaviors of Fibroblast-Like Synoviocytes and Ameliorates Type II Collagen-Induced Arthritis in Rats.
Hexokinase 2-mediated glycolysis promotes receptor activator of NF-κB ligand expression in Porphyromonas gingivalis lipopolysaccharide-treated osteoblasts.
Regulatory roles of miRNAs 16, 133a, and 223 on osteoclastic bone destruction caused by breast cancer metastasis.
Loss of chemerin triggers bone remodeling in vivo and in vitro.
Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.
Exosomes derived from osteogenic tumor activate osteoclast differentiation and concurrently inhibit osteogenesis by transferring COL1A1-targeting miRNA-92a-1-5p.
Anti-rheumatoid arthritis effects of iridoid glucosides from Lamiophlomis rotata (Benth.) kudo on adjuvant-induced arthritis in rats by OPG/RANKL/NF-κB signaling pathways.
Milk Polar Lipids Supplementation to Obese Rats During Pregnancy and Lactation Benefited Skeletal Outcomes of Male Offspring.
Plasma Exosomes Derived From Patients With End-Stage Renal Disease and Renal Transplant Recipients Have Different Effects on Vascular Calcification.
Genistein prevents bone loss in type 2 diabetic rats induced by streptozotocin.
The effects of binge alcohol exposure on tooth movement and associated root resorption in rats.
Glyburide inhibits the bone resorption induced by traumatic occlusion in rats.
MicroRNA‑21 serves an important role during PAOO‑facilitated orthodontic tooth movement.
Sialic acid-modified chitosan oligosaccharide-based biphasic calcium phosphate promote synergetic bone formation in rheumatoid arthritis therapy.
Gingival crevicular fluid levels of SLIT3 are increased in periodontal disease.
Fluid Shear Stress Suppresses Osteoclast Differentiation in RAW264.7 Cells through Extracellular Signal-Regulated Kinase 5 (ERK5) Signaling Pathway.
Knee loading repairs osteoporotic osteoarthritis by relieving abnormal remodeling of subchondral bone via Wnt/β-catenin signaling.
Effects Of Triptolide On Tooth Movement And Root Resorption In Rats.
Elevated ATF4 Expression in Odontogenic Keratocysts Epithelia: Potential Involvement in Tissue Hypoxia and Stromal M2 Macrophage Infiltration.
LOX-1 is involved in TLR2 induced RANKL regulation in peri-implantitis.
Increased level of cell-derived microparticles in the cyst fluids of odontogenic keratocysts.
β-Estradiol antagonizes the inhibitory effects of caffeine in BMMSCs via the ERβ-mediated cAMP-dependent PKA pathway.
Role of endoplasmic reticulum stress in disuse osteoporosis.
Knee loading inhibits osteoclast lineage in a mouse model of osteoarthritis.
Jiang H, Xu F, Zeng L, Li C, Chen Y, Wang L, Li Z, Liu R
Journal of ethnopharmacology 2022 Jan 30;283:114714
Journal of ethnopharmacology 2022 Jan 30;283:114714
Total Saponins from Nigella glandulifera Seeds Ameliorate Adjuvant-Induced Rheumatoid Arthritis in Rats by Inhibition of an Inflammatory Response and Bone Erosion.
Zeng L, Li C, Jiang H, Chen Y, Li Z, Xu F, Liu R
BioMed research international 2021;2021:6613527
BioMed research international 2021;2021:6613527
Tomatidine Suppresses the Destructive Behaviors of Fibroblast-Like Synoviocytes and Ameliorates Type II Collagen-Induced Arthritis in Rats.
Yu X, Zhou J, Zhao F, Liu X, Mao Y, Diao L, Wen C, Liu M
Frontiers in pharmacology 2021;12:670707
Frontiers in pharmacology 2021;12:670707
Hexokinase 2-mediated glycolysis promotes receptor activator of NF-κB ligand expression in Porphyromonas gingivalis lipopolysaccharide-treated osteoblasts.
Yu Y, Jiang L, Li J, Lei L, Li H
Journal of periodontology 2021 Sep 29;
Journal of periodontology 2021 Sep 29;
Regulatory roles of miRNAs 16, 133a, and 223 on osteoclastic bone destruction caused by breast cancer metastasis.
Kitayama K, Kawamoto T, Kawakami Y, Hara H, Takemori T, Fujiwara S, Yahiro S, Miyamoto T, Mifune Y, Hoshino Y, Kakutani K, Matsumoto T, Matsushita T, Niikura T, Kuroda R, Akisue T
International journal of oncology 2021 Nov;59(5)
International journal of oncology 2021 Nov;59(5)
Loss of chemerin triggers bone remodeling in vivo and in vitro.
Han L, Zhang Y, Wan S, Wei Q, Shang W, Huang G, Fang P, Min W
Molecular metabolism 2021 Nov;53:101322
Molecular metabolism 2021 Nov;53:101322
Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.
Jia X, Zhu H, Li G, Lan M, Li X, Huang M, Xu W, Wu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111321
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111321
Exosomes derived from osteogenic tumor activate osteoclast differentiation and concurrently inhibit osteogenesis by transferring COL1A1-targeting miRNA-92a-1-5p.
Yu L, Sui B, Fan W, Lei L, Zhou L, Yang L, Diao Y, Zhang Y, Li Z, Liu J, Hao X
Journal of extracellular vesicles 2021 Jan;10(3):e12056
Journal of extracellular vesicles 2021 Jan;10(3):e12056
Anti-rheumatoid arthritis effects of iridoid glucosides from Lamiophlomis rotata (Benth.) kudo on adjuvant-induced arthritis in rats by OPG/RANKL/NF-κB signaling pathways.
Zhao X, Jiang S, Dong Q, Dang J, Liu Z, Han H, Tao Y, Yue H
Journal of ethnopharmacology 2021 Feb 10;266:113402
Journal of ethnopharmacology 2021 Feb 10;266:113402
Milk Polar Lipids Supplementation to Obese Rats During Pregnancy and Lactation Benefited Skeletal Outcomes of Male Offspring.
Han L, Du M, Ren F, Mao X
Molecular nutrition & food research 2021 Aug;65(15):e2001208
Molecular nutrition & food research 2021 Aug;65(15):e2001208
Plasma Exosomes Derived From Patients With End-Stage Renal Disease and Renal Transplant Recipients Have Different Effects on Vascular Calcification.
Lin X, Zhu T, Xu F, Zhong JY, Li F, Shan SK, Wu F, Guo B, Zheng MH, Wang Y, Xu QS, Liao XB, Lu HY, Xie XB, Yuan LQ
Frontiers in cell and developmental biology 2020;8:618228
Frontiers in cell and developmental biology 2020;8:618228
Genistein prevents bone loss in type 2 diabetic rats induced by streptozotocin.
Lu R, Zheng Z, Yin Y, Jiang Z
Food & nutrition research 2020;64
Food & nutrition research 2020;64
The effects of binge alcohol exposure on tooth movement and associated root resorption in rats.
Yang F, Wang XX, Li J, Nie FJ, Cui Q, Fu YJ, Zhang J
Alcohol (Fayetteville, N.Y.) 2020 Nov;88:1-9
Alcohol (Fayetteville, N.Y.) 2020 Nov;88:1-9
Glyburide inhibits the bone resorption induced by traumatic occlusion in rats.
Arita Y, Yoshinaga Y, Kaneko T, Kawahara Y, Nakamura K, Ohgi K, Arita S, Ryu T, Takase M, Sakagami R
Journal of periodontal research 2020 Jun;55(3):464-471
Journal of periodontal research 2020 Jun;55(3):464-471
MicroRNA‑21 serves an important role during PAOO‑facilitated orthodontic tooth movement.
Zhang Y, Tian Y, Yang X, Zhao Z, Feng C, Zhang Y
Molecular medicine reports 2020 Jul;22(1):474-482
Molecular medicine reports 2020 Jul;22(1):474-482
Sialic acid-modified chitosan oligosaccharide-based biphasic calcium phosphate promote synergetic bone formation in rheumatoid arthritis therapy.
Xu XL, Shu GF, Wang XJ, Qi J, Jin FY, Shen QY, Ying XY, Ji JS, Du YZ
Journal of controlled release : official journal of the Controlled Release Society 2020 Jul 10;323:578-590
Journal of controlled release : official journal of the Controlled Release Society 2020 Jul 10;323:578-590
Gingival crevicular fluid levels of SLIT3 are increased in periodontal disease.
Zhong W, Peng Y, Yue E, Huang B, Zhang W, Zhao Z, Jiang J, Wang Q, Zhao H
Oral diseases 2020 Jan;26(1):182-192
Oral diseases 2020 Jan;26(1):182-192
Fluid Shear Stress Suppresses Osteoclast Differentiation in RAW264.7 Cells through Extracellular Signal-Regulated Kinase 5 (ERK5) Signaling Pathway.
Ma C, Geng B, Zhang X, Li R, Yang X, Xia Y
Medical science monitor : international medical journal of experimental and clinical research 2020 Jan 8;26:e918370
Medical science monitor : international medical journal of experimental and clinical research 2020 Jan 8;26:e918370
Knee loading repairs osteoporotic osteoarthritis by relieving abnormal remodeling of subchondral bone via Wnt/β-catenin signaling.
Zheng W, Ding B, Li X, Liu D, Yokota H, Zhang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):3399-3412
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):3399-3412
Effects Of Triptolide On Tooth Movement And Root Resorption In Rats.
Yang F, Wang XX, Ma D, Cui Q, Zheng H, Liu XC, Zhang J
Drug design, development and therapy 2019;13:3963-3975
Drug design, development and therapy 2019;13:3963-3975
Elevated ATF4 Expression in Odontogenic Keratocysts Epithelia: Potential Involvement in Tissue Hypoxia and Stromal M2 Macrophage Infiltration.
Zhong WQ, Li ZZ, Jiang H, Zou YP, Wang HT, Cai Y, Zhao Y, Zhao JH
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2019 Nov;67(11):801-812
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2019 Nov;67(11):801-812
LOX-1 is involved in TLR2 induced RANKL regulation in peri-implantitis.
Zhang Q, Liu J, Ma L, Bai N, Xu H
International immunopharmacology 2019 Dec;77:105956
International immunopharmacology 2019 Dec;77:105956
Increased level of cell-derived microparticles in the cyst fluids of odontogenic keratocysts.
Man QW, Zhong WQ, Ren JG, Liu JY, Zheng YY, Li RF, Nyimi BF, Chen G, Zhao YF, Liu B
International journal of oncology 2018 Jun;52(6):1863-1874
International journal of oncology 2018 Jun;52(6):1863-1874
β-Estradiol antagonizes the inhibitory effects of caffeine in BMMSCs via the ERβ-mediated cAMP-dependent PKA pathway.
Wang C, Zhou Y, Guan X, Yu M, Wang H
Toxicology 2018 Feb 1;394:1-10
Toxicology 2018 Feb 1;394:1-10
Role of endoplasmic reticulum stress in disuse osteoporosis.
Li J, Yang S, Li X, Liu D, Wang Z, Guo J, Tan N, Gao Z, Zhao X, Zhang J, Gou F, Yokota H, Zhang P
Bone 2017 Apr;97:2-14
Bone 2017 Apr;97:2-14
Knee loading inhibits osteoclast lineage in a mouse model of osteoarthritis.
Li X, Yang J, Liu D, Li J, Niu K, Feng S, Yokota H, Zhang P
Scientific reports 2016 Apr 18;6:24668
Scientific reports 2016 Apr 18;6:24668
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 23408-1-AP( RANKL Antibody) at dilution of 1:700
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RANKL antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human RANKL. This antibody recognizes human antigen. The RANKL antibody has been validated for the following applications: ELISA, WB, IHC analysis.