BAF462

antibody from R&D Systems

Targeting: TNFSF11 CD254, ODF, OPGL, RANKL, TRANCE

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

BAF462

Provider

R&D Systems

Product name

Mouse TRANCE/TNFSF11/RANK L Biotinylated Antibody

Antibody type

Polyclonal

Description

Antigen Affinity-purified. Detects mouse TRANCE in ELISAs and Western blots. In sandwich immunoassays, less than 0.2% cross-reactivity with recombinant human (rh) TRANCE, recombinant mouse (rm) RANK, rhCD40 Ligand, and rmOPG is observed.

Reactivity

Mouse

Host

Goat

Conjugate

Biotin

Antigen sequence

O35235


Isotype

IgG

Vial size

50 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Systemic lentivirus-mediated delivery of short hairpin RNA targeting calcium release-activated calcium channel 3 as gene therapy for collagen-induced arthritis.

Liu S, Kiyoi T, Takemasa E, Maeyama K
Journal of immunology (Baltimore, Md. : 1950) 2015 Jan 1;194(1):76-83

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OX40 signals during priming on dendritic cells inhibit CD4 T cell proliferation: IL-4 switches off OX40 signals enabling rapid proliferation of Th2 effectors.

Kim MY, Bekiaris V, McConnell FM, Gaspal FM, Raykundalia C, Lane PJ
Journal of immunology (Baltimore, Md. : 1950) 2005 Feb 1;174(3):1433-7

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OX40 signals during priming on dendritic cells inhibit CD4 T cell proliferation: IL-4 switches off OX40 signals enabling rapid proliferation of Th2 effectors.

Kim MY, Bekiaris V, McConnell FM, Gaspal FM, Raykundalia C, Lane PJ
Journal of immunology (Baltimore, Md. : 1950) 2005 Feb 1;174(3):1433-7

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IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NF-kappa B ligand/osteoprotegerin balance.

Lubberts E, van den Bersselaar L, Oppers-Walgreen B, Schwarzenberger P, Coenen-de Roo CJ, Kolls JK, Joosten LA, van den Berg WB
Journal of immunology (Baltimore, Md. : 1950) 2003 Mar 1;170(5):2655-62

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IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NF-kappa B ligand/osteoprotegerin balance.

Lubberts E, van den Bersselaar L, Oppers-Walgreen B, Schwarzenberger P, Coenen-de Roo CJ, Kolls JK, Joosten LA, van den Berg WB
Journal of immunology (Baltimore, Md. : 1950) 2003 Mar 1;170(5):2655-62

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MLO-Y4 osteocyte-like cells support osteoclast formation and activation.

Zhao S, Zhang YK, Harris S, Ahuja SS, Bonewald LF
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002 Nov;17(11):2068-79