Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN500805 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (Center) antibody
- Antibody type
- Polyclonal
- Antigen
- sRANK-L antibody was raised against a 14 amino acid peptide from near the center of Human sRANK-L.
- Description
- Immunoaffinity Chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Center
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Evidence that receptor activator of nuclear factor (NF)-kappaB ligand can suppress cell proliferation and induce apoptosis through activation of a NF-kappaB-independent and TRAF6-dependent mechanism.
Interleukin-7 stimulates osteoclast formation by up-regulating the T-cell production of soluble osteoclastogenic cytokines.
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis.
TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells.
Bharti AC, Takada Y, Shishodia S, Aggarwal BB
The Journal of biological chemistry 2004 Feb 13;279(7):6065-76
The Journal of biological chemistry 2004 Feb 13;279(7):6065-76
Interleukin-7 stimulates osteoclast formation by up-regulating the T-cell production of soluble osteoclastogenic cytokines.
Weitzmann MN, Cenci S, Rifas L, Brown C, Pacifici R
Blood 2000 Sep 1;96(5):1873-8
Blood 2000 Sep 1;96(5):1873-8
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis.
Kong YY, Yoshida H, Sarosi I, Tan HL, Timms E, Capparelli C, Morony S, Oliveira-dos-Santos AJ, Van G, Itie A, Khoo W, Wakeham A, Dunstan CR, Lacey DL, Mak TW, Boyle WJ, Penninger JM
Nature 1999 Jan 28;397(6717):315-23
Nature 1999 Jan 28;397(6717):315-23
TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells.
Wong BR, Rho J, Arron J, Robinson E, Orlinick J, Chao M, Kalachikov S, Cayani E, Bartlett FS 3rd, Frankel WN, Lee SY, Choi Y
The Journal of biological chemistry 1997 Oct 3;272(40):25190-4
The Journal of biological chemistry 1997 Oct 3;272(40):25190-4
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of sRANK-L in rat liver tissue lysate with AP30826PU-N at (A) 0.25 and (B) 0.5 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of sRANK-L in human liver tissue with AP30826PU-N at 5 ?g/ml.