RA0785

antibody from Oursmab

Targeting: TNFSF11 CD254, ODF, OPGL, RANKL, TRANCE

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0785

Provider

Oursmab

Product name

Denosumab (Biosimilar Reference Antibody) (TNFSF11)

Antibody type

Monoclonal

Description

Denosumab is a fully human monoclonal antibody used to treat conditions involving excessive bone resorption. Marketed under the brand names Prolia? and Xgeva?, it is approved for multiple indications: postmenopausal osteoporosis, bone loss from hormone ablation in prostate or breast cancer, giant cell tumor of bone, hypercalcemia of malignancy, and to prevent skeletal-related events (such as fractures) in patients with bone metastases from solid tumors. It is administered via subcutaneous injection and works by potently inhibiting osteoclast-mediated bone breakdown.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Denosumab (Biosimilar Reference Antibody) (TNFSF11)-RA0785-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Denosumab (Biosimilar Reference Antibody) (TNFSF11)-RA0785 in a linear range of 3.91-125 ng/mL.