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Learn25068-1-AP
antibody from Proteintech Group
Targeting: DDX58
DKFZp434J1111, FLJ13599, RIG-1, RIG-I, RIG1
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 25068-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- RIG-1/DDX58 antibody
- Antibody type
- Polyclonal
- Description
- RIG-1/DDX58 antibody (Cat. #25068-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Betrixaban activates cGAS and ERVs to promote dual nucleic-sensing antiviral immunity.
Targeting G9a Exerts Pleiotropic Suppression in Triple-Negative Breast Cancer Cells: Cooperatively Inducing Pyroptosis and Apoptosis.
Context-specific roles of DDX60 in colorectal cancer via autophagy regulation and DDX58 signaling.
Impaired hematopoiesis and embryonic lethality at midgestation of mice lacking both lipid transfer proteins VPS13A and VPS13C.
Defect in hematopoiesis and embryonic lethality at midgestation of Vps13a/Vps13c double knockout mice.
Porcine epidemic diarrhea virus nsp14 inhibited IFN-Ⅰ production by targeting RIG-I for degradation.
Differential Effects of Extracellular Vesicles from Two Different Glioblastomas on Normal Human Brain Cells.
IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus.
A tale of two tumors: differential, but detrimental, effects of glioblastoma extracellular vesicles (EVs) on normal human brain cells.
IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus.
RIG-I promotes IFN/JAK2 expression and the endoplasmic reticulum stress response to inhibit chemoradiation resistance in nasopharyngeal carcinoma.
Chen X, Zhao Y, Xie Y, Liu T, Wang H, Wang X, Guo X, You F
EMBO molecular medicine 2026 May;18(5):1563-1591
EMBO molecular medicine 2026 May;18(5):1563-1591
Targeting G9a Exerts Pleiotropic Suppression in Triple-Negative Breast Cancer Cells: Cooperatively Inducing Pyroptosis and Apoptosis.
Li J, Zhang G, Liu T, Yan X, Ma M
Biomolecules 2026 Feb 25;16(3)
Biomolecules 2026 Feb 25;16(3)
Context-specific roles of DDX60 in colorectal cancer via autophagy regulation and DDX58 signaling.
Wang K, Zhang C, Ma C, Fu X, Geng L, Jiang H
Cancer genetics 2026 Apr;302-303:124-138
Cancer genetics 2026 Apr;302-303:124-138
Impaired hematopoiesis and embryonic lethality at midgestation of mice lacking both lipid transfer proteins VPS13A and VPS13C.
Xu P, Mancuso RI, Leonzino M, Zeiss CJ, Krause DS, De Camilli P
PLoS biology 2025 Sep;23(9):e3003393
PLoS biology 2025 Sep;23(9):e3003393
Defect in hematopoiesis and embryonic lethality at midgestation of Vps13a/Vps13c double knockout mice.
Xu P, Mancuso RI, Leonzino M, Zeiss CJ, Krause DS, De Camilli P
bioRxiv : the preprint server for biology 2025 May 13;
bioRxiv : the preprint server for biology 2025 May 13;
Porcine epidemic diarrhea virus nsp14 inhibited IFN-Ⅰ production by targeting RIG-I for degradation.
Li S, Wang L, Wen Y, Han J, Hou J, Hou Z, Xie J, Li H, Li X, Yang Y, Feng R
Virology 2025 Apr;605:110451
Virology 2025 Apr;605:110451
Differential Effects of Extracellular Vesicles from Two Different Glioblastomas on Normal Human Brain Cells.
Wang M, Graner AN, Knowles B, McRae C, Fringuello A, Paucek P, Gavrilovic M, Redwine M, Hanson C, Coughlan C, Grimaldo-Garcia S, Metzger B, Bolus V, Kopper TJ, Smith M, Zhou W, Lenz M, Abosch A, Ojemann S, Lillehei KO, Yu X, Graner MW
Neurology international 2024 Nov 6;16(6):1355-1384
Neurology international 2024 Nov 6;16(6):1355-1384
IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus.
Guney MH, Nagalekshmi K, McCauley SM, Carbone C, Aydemir O, Luban J
Proceedings of the National Academy of Sciences of the United States of America 2024 Jul 16;121(29):e2404349121
Proceedings of the National Academy of Sciences of the United States of America 2024 Jul 16;121(29):e2404349121
A tale of two tumors: differential, but detrimental, effects of glioblastoma extracellular vesicles (EVs) on normal human brain cells.
Wang M, Graner AN, Knowles B, McRae C, Fringuello A, Paucek P, Gavrilovic M, Redwine M, Hanson C, Coughlan C, Metzger B, Bolus V, Kopper T, Smith M, Zhou W, Lenz M, Abosch A, Ojemann S, Lillehei KO, Yu X, Graner MW
bioRxiv : the preprint server for biology 2024 Apr 12;
bioRxiv : the preprint server for biology 2024 Apr 12;
IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus.
Guney MH, Nagalekshmi K, McCauley SM, Carbone C, Aydemir O, Luban J
bioRxiv : the preprint server for biology 2023 Dec 12;
bioRxiv : the preprint server for biology 2023 Dec 12;
RIG-I promotes IFN/JAK2 expression and the endoplasmic reticulum stress response to inhibit chemoradiation resistance in nasopharyngeal carcinoma.
Jing D, Zhou W, Shen L, Zhang Q, Xie WT, Shen E, Li Z, Shen LF, Sun LQ
Cancer medicine 2019 Oct;8(14):6344-6357
Cancer medicine 2019 Oct;8(14):6344-6357
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A431 cells were subjected to SDS PAGE followed by western blot with 25068-1-AP( DDX58 Antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DDX58 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human DDX58. This antibody recognizes human antigen. The DDX58 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
