Ab125359

antibody from Aladdin Scientific

Targeting: DDX58 DKFZp434J1111, FLJ13599, RIG-1, RIG-I, RIG1

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Validation data

Product number: Ab125359 - Provider product page
Provider: Aladdin Scientific
Product name: Recombinant RIG-I/DDX58 Antibody
Antibody type: Recombinant
Description: Rabbit anti Human RIG-I Antibody, Recombinant (R04-8J4), could be used for WB and so on.Application:WB: 1/500-1/1000Protein FunctionInvolved in innate immune defense against viruses. Upon interaction with intracellular dsRNA produced during viral replication, triggers a transduction cascade involving MAVS/IPS1, which results in the activation of NF-kappa-B, IRF3 and IRF7 and the induction of the expression of antiviral cytokines such as IFN-beta and RANTES (CCL5). Detects dsRNA produced from non-self dsDNA by RNA polymerase III, such as Epstein-Barr virus-encoded RNAs (EBERs). Essential for the production of interferons in response to RNA viruses including paramyxoviruses, influenza viruses, Japanese encephalitis virus and HCV.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: AA 220-450
Antibody clone number: R04-8J4
Vial size: 100μl,10μl,1ml,50μl
Concentration: 3 mg/ml
Storage: Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

DDX58 protein structure - Ab125359 shown in red.