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- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
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- Product number
- 21377-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- SASS6 antibody
- Antibody type
- Polyclonal
- Description
- SASS6 antibody (Cat. #21377-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Bi-allelic variants in CEP295 cause Seckel-like syndrome presenting with primary microcephaly, developmental delay, intellectual disability, short stature, craniofacial and digital abnormalities.
The mechanism of acentrosomal spindle assembly in human oocytes.
Knockdown of SASS6 reduces growth of MDA‑MB‑231 triple‑negative breast cancer cells through arrest of the cell cycle at the G2/M phase.
SAS-6 Association with γ-Tubulin Ring Complex Is Required for Centriole Duplication in Human Cells.
Li N, Xu Y, Chen H, Lin J, AlAbdi L, Bekheirnia MR, Li G, Gofin Y, Bekheirnia N, Faqeih E, Chen L, Chang G, Tang J, Yao R, Yu T, Wang X, Fu W, Fu Q, Shen Y, Alkuraya FS, Machol K, Wang J
EBioMedicine 2024 Jan;99:104940
EBioMedicine 2024 Jan;99:104940
The mechanism of acentrosomal spindle assembly in human oocytes.
Wu T, Dong J, Fu J, Kuang Y, Chen B, Gu H, Luo Y, Gu R, Zhang M, Li W, Dong X, Sun X, Sang Q, Wang L
Science (New York, N.Y.) 2022 Nov 18;378(6621):eabq7361
Science (New York, N.Y.) 2022 Nov 18;378(6621):eabq7361
Knockdown of SASS6 reduces growth of MDA‑MB‑231 triple‑negative breast cancer cells through arrest of the cell cycle at the G2/M phase.
Du L, Jing J, Wang Y, Xu X, Sun T, Shi Y, Wang W, Tian B, Han C, Zhao X, Chang H
Oncology reports 2021 Jun;45(6)
Oncology reports 2021 Jun;45(6)
SAS-6 Association with γ-Tubulin Ring Complex Is Required for Centriole Duplication in Human Cells.
Gupta H, Rajeev R, Sasmal R, Radhakrishnan RM, Anand U, Chandran H, Aparna NR, Agasti S, Manna TK
Current biology : CB 2020 Jun 22;30(12):2395-2403.e4
Current biology : CB 2020 Jun 22;30(12):2395-2403.e4
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 21377-1-AP(SASS6 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP result of anti-SAS6 (21377-1-AP for IP and Detection) with HeLa cells.
- Sample type
- cell line
