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- References [14]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 17069-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17069-1-AP, RRID:AB_2262009
- Product name
- EIF5A1/EIF5A2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated EIF5A1/EIF5A2 antibody (Cat. #17069-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references MiR-5189-3p Suppresses cell Proliferation, Invasion and Migration Through Targeting EIF5A2 in Laryngeal Squamous Cell Carcinoma.
Identification of genes that promote PI3K pathway activation and prostate tumour formation.
Progressive alterations in polysomal architecture and activation of ribosome stalling relief factors in a mouse model of Huntington's disease.
SUMOylation modulates eIF5A activities in both yeast and pancreatic ductal adenocarcinoma cells.
Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr.
High eukaryotic initiation factor 5A2 expression predicts poor prognosis and may participate in the SNHG16/miR-10b-5p/EIF5A2 regulatory axis in head and neck squamous cell carcinoma.
Eukaryotic Initiation Factor 5A2 Regulates Expression of Antiviral Genes.
Global analyses of mRNA expression in human sensory neurons reveal eIF5A as a conserved target for inflammatory pain.
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
Knockdown of EIF5A2 inhibits the malignant potential of non-small cell lung cancer cells.
EIF5A2 is a novel chemoresistance gene in breast cancer.
Cisplatin sensitivity is enhanced in non-small cell lung cancer cells by regulating epithelial-mesenchymal transition through inhibition of eukaryotic translation initiation factor 5A2.
Down-regulation of eIF5A-2 prevents epithelial-mesenchymal transition in non-small-cell lung cancer cells.
Novel functional MAR elements of double minute chromosomes in human ovarian cells capable of enhancing gene expression.
Lou D, Jia Q, Zhang H, Wang J, Liu L, Liu Z, Jia X, Wang J, Shan C
Biochemical genetics 2024 Jun;62(3):1603-1616
Biochemical genetics 2024 Jun;62(3):1603-1616
Identification of genes that promote PI3K pathway activation and prostate tumour formation.
Francis JC, Capper A, Rust AG, Ferro K, Ning J, Yuan W, de Bono J, Pettitt SJ, Swain A
Oncogene 2024 Jun;43(24):1824-1835
Oncogene 2024 Jun;43(24):1824-1835
Progressive alterations in polysomal architecture and activation of ribosome stalling relief factors in a mouse model of Huntington's disease.
Martin-Solana E, Diaz-Lopez I, Mohamedi Y, Ventoso I, Fernandez JJ, Fernandez-Fernandez MR
Neurobiology of disease 2024 Jun 1;195:106488
Neurobiology of disease 2024 Jun 1;195:106488
SUMOylation modulates eIF5A activities in both yeast and pancreatic ductal adenocarcinoma cells.
Seoane R, Lama-Díaz T, Romero AM, El Motiam A, Martínez-Férriz A, Vidal S, Bouzaher YH, Blanquer M, Tolosa RM, Castillo Mewa J, Rodríguez MS, García-Sastre A, Xirodimas D, Sutherland JD, Barrio R, Alepuz P, Blanco MG, Farràs R, Rivas C
Cellular & molecular biology letters 2024 Jan 16;29(1):15
Cellular & molecular biology letters 2024 Jan 16;29(1):15
Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr.
Salehi S, Zare A, Prezza G, Bader J, Schneider C, Fischer U, Meissner F, Mann M, Briese M, Sendtner M
Nature communications 2023 Jul 12;14(1):4158
Nature communications 2023 Jul 12;14(1):4158
High eukaryotic initiation factor 5A2 expression predicts poor prognosis and may participate in the SNHG16/miR-10b-5p/EIF5A2 regulatory axis in head and neck squamous cell carcinoma.
Ye S, Wang D, Jin M, Du J, Chen X, Zhang H, Zhou C, Fang S, Liu K
Journal of clinical laboratory analysis 2023 Jan;37(1):e24820
Journal of clinical laboratory analysis 2023 Jan;37(1):e24820
Eukaryotic Initiation Factor 5A2 Regulates Expression of Antiviral Genes.
Farache D, Liu L, Lee ASY
Journal of molecular biology 2022 May 30;434(10):167564
Journal of molecular biology 2022 May 30;434(10):167564
Global analyses of mRNA expression in human sensory neurons reveal eIF5A as a conserved target for inflammatory pain.
Chase R, de la Peña JB, Smith PR, Lawson J, Lou TF, Stanowick AD, Black BJ, Campbell ZT
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22422
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22422
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
Ma D, Zheng B, Liu HL, Zhao YB, Liu X, Zhang XH, Li Q, Shi WB, Suzuki T, Wen JK
PLoS biology 2020 Aug;18(8):e3000808
PLoS biology 2020 Aug;18(8):e3000808
Knockdown of EIF5A2 inhibits the malignant potential of non-small cell lung cancer cells.
Chen C, Zhang B, Wu S, Song Y, Li J
Oncology letters 2018 Apr;15(4):4541-4549
Oncology letters 2018 Apr;15(4):4541-4549
EIF5A2 is a novel chemoresistance gene in breast cancer.
Liu Y, Du F, Chen W, Yao M, Lv K, Fu P
Breast cancer (Tokyo, Japan) 2015 Nov;22(6):602-7
Breast cancer (Tokyo, Japan) 2015 Nov;22(6):602-7
Cisplatin sensitivity is enhanced in non-small cell lung cancer cells by regulating epithelial-mesenchymal transition through inhibition of eukaryotic translation initiation factor 5A2.
Xu G, Yu H, Shi X, Sun L, Zhou Q, Zheng D, Shi H, Li N, Zhang X, Shao G
BMC pulmonary medicine 2014 Nov 7;14:174
BMC pulmonary medicine 2014 Nov 7;14:174
Down-regulation of eIF5A-2 prevents epithelial-mesenchymal transition in non-small-cell lung cancer cells.
Xu GD, Shi XB, Sun LB, Zhou QY, Zheng DW, Shi HS, Che YL, Wang ZS, Shao GF
Journal of Zhejiang University. Science. B 2013 Jun;14(6):460-7
Journal of Zhejiang University. Science. B 2013 Jun;14(6):460-7
Novel functional MAR elements of double minute chromosomes in human ovarian cells capable of enhancing gene expression.
Jin Y, Liu Z, Cao W, Ma X, Fan Y, Yu Y, Bai J, Chen F, Rosales J, Lee KY, Fu S
PloS one 2012;7(2):e30419
PloS one 2012;7(2):e30419
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 17069-1-AP(EIF5A2 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 17069-1-AP(EIF5A2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The EIF5A2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human EIF5A2. This antibody recognizes human, mouse, rat antigen. The EIF5A2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
