HPA023626

antibody from Atlas Antibodies

Targeting: ITGB6

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA023626

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA023626, RRID:AB_2671267

Product name

Anti-ITGB6

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human ITGB6, Gene description: integrin, beta 6, Validated applications: ICC, IHC, Uniprot ID: P18564, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.2 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Integrin αvβ6 mediates the immune escape through regulation of PD-L1 and serves as a novel marker for immunotherapy of colon carcinoma

Yu J
American Journal of Cancer Research 2024;14(5):2608-2625

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Anti-integrin αvβ6 autoantibodies are a potential biomarker for ulcerative colitis-like immune checkpoint inhibitor-induced colitis

Yokode M, Shiokawa M, Kawakami H, Kuwada T, Nishikawa Y, Muramoto Y, Kitamoto H, Okabe M, Yamazaki H, Okamoto N, Morita T, Ohno K, Nakanishi R, Takimoto I, Yasuda M, Chikugo K, Matsumoto S, Yoshida H, Ota S, Nakamura T, Okada H, Hirano T, Kakiuchi N, Matsumori T, Yamamoto S, Uza N, Ooi M, Kodama Y, Chiba T, Hayashi H, Seno H
British Journal of Cancer 2024;130(9):1552-1560

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Analysis of the distribution and expression of some tumor invasiveness markers in palate squamous cell carcinomas

Pătru A
Romanian Journal of Morphology and Embryology 2021;61(4):1259-1278

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Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression

Kemper M, Schiecke A, Maar H, Nikulin S, Poloznikov A, Galatenko V, Tachezy M, Gebauer F, Lange T, Riecken K, Tonevitsky A, Aigner A, Izbicki J, Schumacher U, Wicklein D
Journal of Experimental & Clinical Cancer Research 2021;40(1)

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SPECT/CT Imaging, Biodistribution and Radiation Dosimetry of a 177Lu-DOTA-Integrin αvβ6 Cystine Knot Peptide in a Pancreatic Cancer Xenograft Model

Sachindra S, Hellberg T, Exner S, Prasad S, Beindorff N, Rogalla S, Kimura R, Gambhir S, Wiedenmann B, Grötzinger C
Frontiers in Oncology 2021;11

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Affinity proteomic profiling of plasma for proteins associated to area-based mammographic breast density

Byström S, Eklund M, Hong M, Fredolini C, Eriksson M, Czene K, Hall P, Schwenk J, Gabrielson M
Breast Cancer Research 2018;20(1)

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ITGB6 loss-of-function mutations cause autosomal recessive amelogenesis imperfecta

Wang S, Choi M, Richardson A, Reid B, Lin B, Wang S, Kim J, Simmer J, Hu J
Human Molecular Genetics 2014;23(8):2157-2163

Immunocytochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm & cell junctions.

Sample type

Human