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- References [416]
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- Product number
- 13798-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13798-1-AP, RRID:AB_2266318
- Product name
- MFN1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MFN1 antibody (Cat. #13798-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Sirtuin 4 Knockout Aggravates Sepsis-Induced Acute Liver Injury by Enhancing Mitochondrial Fission and Mitophagy in Hepatocytes.
Chronic intermittent hypoxia increases Parkinson's disease susceptibility via PPARα-mediated lipid droplet-mitochondrial dysfunction.
Curcumin augments mitophagy via Nrf2-PINK1-mediated, Parkin-dependent ubiquitination to suppress ferroptosis in post-cardiac arrest brain injury.
Reproductive toxicity mechanisms of PNMC: Evidence from mitochondrial dysfunction and hormone synthesis disruption in the KGN cells.
The purinergic receptor P2rx7 mediated ATP sensing is required to prevent bone aging by directing mitochondrial fitness of MSCs.
Effects of local skeletal muscle cooling prior to acute exercise and endurance training on mitochondrial adaptation in mice.
Targeting NME3 to Restore Mitochondrial Fission-Fusion Balance Defines a Novel Disease-Modifying Strategy for Parkinson's Disease.
Fibroblast growth factor-inducible 14 accelerates pulmonary fibrosis by inducing fibroblast senescence in mice.
Intermittent fasting attenuates ovarian chronic inflammation in obese mice by inhibiting the CXCL12-CXCR4 axis.
Sennoside A alleviates HFD-induced MAFLD by protecting intestinal barrier function through TLR4/NF-κB and mitochondrial quality control.
YAP in synovial macrophages mitigates mechanically-induced osteoarthritis by preserving mitochondrial fusion.
Mitochondrial fission process 1 is required for bovine oocyte maturation through regulation of mitochondrial function and dynamics.
Overexpression of mitofusin 2 ameliorates inflammation and oxidative stress in lipopolysaccharide-induced mastitis model by regulating phosphofurin acidic cluster sorting protein 2.
The Neuroprotective Role of Ginsenoside Rg1 Against Cerebral Ischemia-Reperfusion Damage Through Inhibition of Mitophagy via Blocking Mitophagosome-Lysosome Fusion.
Lobetyolin alleviates microglial inflammation by activating CK2α/Opa1-mediated mitochondrial fusion in ischemic stroke.
Nobiletin Ameliorates Skeletal Muscle Performance in D-Galactose-Induced Aging Mice by Boosting Aerobic Metabolism.
Stress-induced mitochondrial fragmentation in endothelial cells disrupts blood-retinal barrier integrity causing neurodegeneration.
Macelignan, a lignan from Myristica fragrans Houtt., rescues mitochondrial homeostasis and prevents cognitive decline in vascular dementia by modulating the mTOR-Mitophagy axis.
Endoplasmic Reticulum Stress Induced by Turbulence of Mitochondrial Fusion and Fission Was Involved in Isoproterenol-Induced H9c2 Cell Injury.
The UBC/SIRT5/DRP1 axis regulates mitochondrial dynamics to alleviate Staphylococcus aureus-induced oxidative stress and senescence in bovine mammary epithelial cells.
Mesenchymal Stem Cell-derived Exosomes Alleviate Oxidative Stress and Brain Injuries Through Promoting OPA1 Mediated Mitochondrial Fusion After Intracerebral Hemorrhage.
PM(10) Disrupts Mitochondrial Homeostasis in Corneal Epithelial Cells: Protective Effects of SKQ1.
TRPV4 Deficiency Shifts Mitochondrial Dynamics Toward a Fragmented Morphology in Primary Microglia.
Trimethylamine-N-oxide disrupts spermatogenesis by inducing mitochondrial oxidative stress injury through Hippo signaling.
Hippocampal HDAC7 induces perioperative neurocognitive disorders via an NF-κB-MFN2-ACSL4 ferroptosis pathway.
Mitochondrial TRPV1 exacerbates cognitive deficits in sepsis-associated encephalopathy by driving microglial metabolic reprogramming.
Di-(2-Ethylhexyl) phthalate causes testicular ferroptosis though deficiency of androgen receptor and disruption of mitochondrial quality control.
Brain and Liver Dual-Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy.
Florfenicol impairs steroid hormone secretion in bovine ovarian granulosa cells: Involvement of the cAMP/PKA/StAR signaling pathway and oxidative stress.
The Role of Placental MFF-Mediated Mitochondrial Fission in Gestational Diabetes Mellitus.
Metformin Activation of Sirtuin 3 Signaling Regulates Mitochondrial Function Improves Diabetes-Associated Cognitive Impairment.
Silencing ATF3 mediates mitochondrial homeostasis and improves ischemic stroke through regulating the MAPK signaling pathway.
MFN2-a multifaceted guardian against Parkinson's pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis.
Bavachin suppresses proliferation of laryngopharyngeal cancer by regulating the STAT3 and MAPK signaling pathways.
Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.
1,25(OH)(2)D(3) up-regulated mitochondrial dynamics and biogenesis to modulate steroidogenesis in the scent glands of muskrats (Ondatra zibethicus).
Mechanism of mitofusin 2, mitochondria-associated membrane, and the mitochondrial pathway in alleviating oxidative stress and cell senescence in bovine mammary epithelial cells.
Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway.
Kaempferol improves mitochondrial homeostasis via mitochondrial dynamics and mitophagy in diabetic kidney disease.
Sex-specific impact of selective reduced uterine placental perfusion model of preeclampsia on fetal cardiac maturation and mitochondrial function.
Gestational zearalenone causes fetal intrauterine growth restriction partially through deriving ROS-Drp1 mediated placental PANoptosis.
Porcine GWAS identifies ACOT11 as regulator for macrophage IL-1β maturation via IFNGR2 palmitoylation.
Oxytocin Regulated Neuroinflammation through OTR/Mitochondria Mediated Pathway to Improve Hypoxia-Induced Brain Injury.
Skeletal Muscle PGC-1α Remodels Mitochondrial Phospholipidome but Does Not Alter Energy Efficiency for ATP Synthesis.
PPP1R3G inhibition impairs OPCs differentiation and myelination in aged mice.
MTCH2 modulates CPT1 activity to regulate lipid metabolism of adipocytes.
Luteoloside alleviates bleomycin-induced pulmonary fibrosis in mice via SIRT1-mediated protective effect against alveolar epithelial cell senescence.
Atrazine-induced hippocampal neurotoxicity: Involvement of Drp1-mediated mitochondrial fission.
Electroacupuncture improves motor function after ischemic stroke via regulating mitochondrial dynamics.
AMPK impairment caused by gelatin disturbs mitochondrial dynamics leading to enhanced phagocytosis of bacteria in PMA-stimulated U937 cells.
Mfn2 Regulates Scleral Remodeling in Myopia by Maintaining Endoplasmic Reticulum Homeostasis in Scleral Fibroblasts.
TAAR1 deficiency impairs mitochondrial dynamics and synaptic integrity in the medial prefrontal cortex and associated cognition in mice.
MYC affects mitochondrial function in IgA nephropathy by promoting the degradation of MFN1 through HRD1.
Leucokinin VIII acetate mitigates asthma severity by targeting ADCK5-induced cellular senescence.
Cisplatin transported by COX17 induces cochlear damage by binding Myosin IIA to regulate cell pyroptosis induced by mitochondrial dysfunction.
Effect of disruption of mitochondrial and endoplasmic reticulum calcium homeostasis on neurites in hydrogen peroxide- and ionomycin-treated cells.
Protective effect of astragaloside IV against zinc oxide nanoparticles induced human neuroblastoma SH-SY5Y cell death: a focus on mitochondrial quality control.
The effect of Hydrogen-rich water on retinal degeneration in the outer nuclear layer of simulated weightlessness rats.
Kirenol alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the CK2/AKT pathway.
Trehalose attenuates testicular aging by activating autophagy and improving mitochondrial quality.
Instant fluorescence lifetime imaging microscopy reveals mechano-metabolic reprogramming of stromal cells in breast cancer peritumoral microenvironments.
Overexpression of c-Myc triggers p62 aggregation-mediated mitochondrial mitophagy in cabozantinib resistance of hepatocellular carcinoma.
ZLN005, a PGC-1α agonist, delays photoreceptor degeneration by enhancing mitochondrial biogenesis in a murine model of retinitis pigmentosa.
Dual regulation of mitochondrial fusion by Parkin-PINK1 and OMA1.
Leucine 7 is a key residue for mutant huntingtin-induced mitochondrial pathology and neurotoxicity in Huntington's disease.
Melatonin refines ovarian mitochondrial dysfunction in PCOS by regulating the circadian rhythm gene Clock.
Impact of POU3F4 mutation on cochlear development and auditory function.
Polystyrene microplastics induce hepatic lipid metabolism and energy disorder by upregulating the NR4A1-AMPK signaling pathway.
PNPLA6 regulates retinal homeostasis by choline through phospholipid turnover.
OPA1 deficiency induces mitophagy through PINK1/Parkin pathway during bovine oocytes maturation.
Neurotoxicity of Realgar: Crosstalk Between UBXD8-DRP1-Regulated Mitochondrial Fission and PINK1-Parkin-Mediated Mitophagy.
Lycium barbarum polysaccharide alleviate cadmium-induced mitochondrial dysfunction mediated pyroptosis in duck liver.
The crucial function of IDO1 in pulmonary fibrosis: From the perspective of mitochondrial fusion in lung fibroblasts and targeted molecular inhibition.
Intratracheal Administration of Polystyrene Micro(nano)plastics with a Mixed Particle Size Promote Pulmonary Fibrosis in Rats by Activating TGF-β1 Signaling and Destabilizing Mitochondrial Dynamics and Mitophagy in a Dose- and Time-Dependent Manner.
Fluoride induces spermatocyte apoptosis by IP3R1/MCU-mediated mitochondrial calcium overload through MAMs.
PINK1 affects mitochondrial oxidative phosphorylation by regulating MFN2 to alleviate diabetic kidney disease.
Ginsenoside Rh2 Exerts a Therapeutic Effect against Myocardial Infarction via Promoting Angiogenesis and Mitochondrial Bioenergetics.
Transient AMPK activation by nutrient stress of high fat diet preserves cardiac electrophysiological stability and protects against arrhythmias.
Downregulation of Mfn2 Contributes to Chronic Postsurgical Pain via Inducing the Pyroptosis of GABAergic Neurons in the Spinal Cord.
Extremely low-frequency electromagnetic field (ELF-EMF) enhances mitochondrial energy production in NARP cybrids.
Tang Bi formula alleviates diabetic sciatic neuropathy via AMPK/PGC-1α/MFN2 pathway activation.
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis.
Klebsiella pneumoniae causes mammary gland damage via FNIP1-mediated mitochondrial dysfunction.
Stress-induced mitochondrial fragmentation in endothelial cells disrupts blood-retinal barrier integrity causing neurodegeneration.
Study on the role of Dihuang Yinzi in regulating the AMPK/SIRT1/PGC-1α pathway to promote mitochondrial biogenesis and improve Alzheimer's disease.
Isovitexin targets SIRT3 to prevent steroid-induced osteonecrosis of the femoral head by modulating mitophagy-mediated ferroptosis.
Correcting mitochondrial loss mitigates NOTCH1-related aortopathy in mice.
Ginsenoside Rb3 Promotes Opa1-Mediated Regenerative Neurogenesis via Activating the Ido1 Pathway in Ischemic Stroke.
The Mitochondria-Targeted Micelle Inhibits Alzheimer's Disease Progression by Alleviating Neuronal Mitochondrial Dysfunction and Neuroinflammation.
Chronic alcohol consumption exacerbates ischemia-associated skeletal muscle mitochondrial dysfunction in a murine model of peripheral artery disease.
SREBP1c-Mediated Transcriptional Repression of YME1L1 Contributes to Acute Kidney Injury by Inducing Mitochondrial Dysfunction in Tubular Epithelial Cells.
Salidroside protects against myocardial infarction via activating MIF-mediated mitochondrial quality control.
Urolithin A provides cardioprotection and mitochondrial quality enhancement preclinically and improves human cardiovascular health biomarkers.
l-Glutamic Acid Alleviates Mastitis in Dairy Cows by Targeting the Sirt5/Nrf2/Prdx1 Signaling Axis and Mitochondrial Function.
PANAXADIOL SAPONIN ALLEVIATES LPS-INDUCED CARDIOMYOPATHY SIMILAR TO DEXAMETHASONE VIA IMPROVING MITOCHONDRIAL QUALITY CONTROL.
Up-regulation of cell apoptosis, autophagy and mitochondrial dynamics in ovarian granulosa cells of Daurian ground squirrels during the pre-hibernation period.
ACTG1 mediates cisplatin resistance in NSCLC through induction of mitochondrial fragmentation.
Hispolon reduces mitochondrial dysfunction and improves fibrosis of diabetes nephropathy by activating AMPK signal and inhibiting mPTP opening.
KDM6B induces demethylation of H3K27me3 in MFN1 to modulate aberrant mitophagy in sepsis-induced acute lung injury.
Multi-Omics Analysis Reveals Distinct Lipid Remodelling and Mitochondrial Stress in SH-SY5Y Cells Modelling Parkinson's Disease.
NDUFAB1 promotes hepatocellular carcinoma progression by disrupting mitochondrial homeostasis and mitophagy pathway.
FUNDC1-dependent mitochondrial-ER membranes mediate mitochondrial dysfunction and melanocyte damage under oxidative stress.
Leber's hereditary optic neuropathy-associated ND1 3733G>C mutation ameliorates the mitochondrial quality control and cellular homeostasis.
Mn(2)O(3) NPs-induced liver injury is potentially associated with gut microbiota dysbiosis in broiler chicken.
Decoding the role of nucleic acid binding protein 2 in lipid dysregulation and hepatocellular carcinoma progression through LKB1-mediated mitochondrial dysfunction.
Melatonin mitigates arsenic and fluoride-induced cardiotoxicity in chickens by maintaining mitochondrial homeostasis.
Targeting Wnt/beta-catenin signaling to attenuate short-chain chlorinated paraffins-triggered hepatocyte mitochondrial fission and subsequent pyroptosis.
NR3C1/GLMN-Mediated FKBP12.6 Ubiquitination Disrupts Calcium Homeostasis and Impairs Mitochondrial Quality Control in Stress-Induced Myocardial Damage.
Radiocleavable rare-earth nanoactivators targeting over-expressed folate receptors induce mitochondrial dysfunction and remodel immune suppressive microenvironment in pancreatic cancer.
PGAM5 aggravated doxorubicin-induced cardiotoxicity by disturbing mitochondrial dynamics and exacerbating cardiomyocytes apoptosis.
O-GlcNAcylation of hexokinase 2 modulates mitochondrial dynamics and enhances the progression of lung cancer.
Dietary salt promotes cognitive impairment through repression of SIRT3/PINK1-mediated mitophagy and fission.
Molybdenum nanodots act as antioxidants for photothermal therapy osteoarthritis.
sLithospermic acid etched ZIF-8 nanoparticles delays osteoarthritis progression by inhibiting inflammatory signaling pathways and rescuing mitochondrial damage.
Schisandrin B Improves Mitochondrial Function and Inhibits HT22 Cell Apoptosis by Regulating Sirt3 Protein.
Evolocumab attenuates myocardial ischemia/reperfusion injury by blocking PCSK9/LIAS-mediated cuproptosis of cardiomyocytes.
Butyrate Regulates Intestinal DNA Virome and Lipopolysaccharide Levels to Prevent High-Fat Diet-Related Liver Damage in Rats.
Pharmacological targeting of the mitochondrial phosphatase PTPMT1 sensitizes hepatocellular carcinoma to ferroptosis.
Loss of lipid droplet-mitochondria contacts confers protection against ethanol-induced cardiotoxicity.
ARMC1 partitions between distinct complexes and assembles MIRO with MTFR to control mitochondrial distribution.
Asparagine transporter supports macrophage inflammation via histone phosphorylation.
Blocking SLC7A11 attenuates the proliferation of esophageal squamous cell carcinoma cells.
Mitochondrial Dysfunction by FADDosome Promotes Gastric Mucosal Injury in Portal Hypertensive Gastropathy.
PTPLAD1 Regulates PHB-Raf Interaction to Orchestrate Epithelial-Mesenchymal and Mitofusion-Fission Transitions in Colorectal Cancer.
Dl-3-n-butylphthalide attenuates cerebral ischemia/reperfusion injury in mice through AMPK-mediated mitochondrial fusion.
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux.
Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation.
Prophylactic Effects of Betaine on Depression and Anxiety Behaviors in Mice with Dextran Sulfate Sodium-Induced Colitis.
mCAUSE: Prioritizing mitochondrial targets that alleviate pancreatic cancer cell phenotypes.
MMP9 drives ferroptosis by regulating GPX4 and iron signaling.
Helicobacter pylori CagA mediated mitophagy to attenuate the NLRP3 inflammasome activation and enhance the survival of infected cells.
Dysregulation of mitochondrial dynamics and mitophagy are involved in high-fat diet-induced steroidogenesis inhibition.
Neuronal HIPK2-HDAC3 axis regulates mitochondrial fragmentation to participate in stroke injury and post-stroke anxiety like behavior.
Resveratrol protects against a high-fat diet-induced neuroinflammation by suppressing mitochondrial fission via targeting SIRT1/PGC-1α.
SIRT1 regulates mitochondrial fission to alleviate high altitude hypoxia inducedcardiac dysfunction in rats via the PGC-1α-DRP1/FIS1/MFF pathway.
Mfn2(R364W), Mfn2(G176S), and Mfn2(H165R) mutations drive Charcot-Marie-Tooth type 2A disease by inducing apoptosis and mitochondrial oxidative phosphorylation damage.
Qifu-yin activates the Keap1/Nrf2/ARE signaling and ameliorates synaptic injury and oxidative stress in APP/PS1 mice.
Apoptosis, Mitochondrial Autophagy, Fission, and Fusion Maintain Mitochondrial Homeostasis in Mouse Liver Under Tail Suspension Conditions.
Dapagliflozin alleviates right heart failure by promoting collagen degradation by reducing ROS levels.
Characterization of fission and fusion mitochondrial dynamics in HD fibroblasts according to patient's severity status.
Yiqihuoxue decoction (GSC) inhibits mitochondrial fission through the AMPK pathway to ameliorate EPCs senescence and optimize vascular aging transplantation regimens.
Contribution of impaired autophagy, mitochondrial dysfunction and abnormal lipolysis to epididymal aging in mice.
Renal denervation ameliorates atrial remodeling in type 2 diabetic rats by regulating mitochondrial dynamics.
Cellular ATP demand creates metabolically distinct subpopulations of mitochondria.
E3 ubiquitin ligase TRIM31 alleviates dopaminergic neurodegeneration by promoting proteasomal degradation of VDAC1 in Parkinson's Disease model.
Hydrogen Protects Mitochondrial Function by Increasing the Expression of PGC-1α and Ameliorating Myocardial Ischaemia-Reperfusion Injury.
Mitochondrial elongation confers protection against doxorubicin-induced cardiotoxicity.
Psmb8 inhibits mitochondrial fission and alleviates myocardial ischaemia/reperfusion injury by targeting Drp1 degradation.
Targeting DUSP26 to drive cardiac mitochondrial dynamics via FAK-ERK signaling in diabetic cardiomyopathy.
Acrolein exposure affects ovarian function by interfering with glycolysis and mitochondrial energy metabolism in mouse.
TRPA1 protects against contrast-induced renal tubular injury by preserving mitochondrial dynamics via the AMPK/DRP1 pathway.
Deafness-associated tRNA(Phe) mutation impaired mitochondrial and cellular integrity.
Metaplastic regeneration in the mouse stomach requires a reactive oxygen species pathway.
Silent information regulator 2 deficiency exacerbates chronic cold exposure-induced colonic injury and p65 activation in mice.
Mitochondrial SIRT3 as a protective factor against cyclosporine A-induced nephrotoxicity.
Puerarin Delays Mammary Gland Aging by Regulating Gut Microbiota and Inhibiting the p38MAPK Signaling Pathway.
Environmental cadmium inhibits testicular testosterone synthesis via Parkin-dependent MFN1 degradation.
Rapamycin alleviates mitochondrial dysfunction in anti-NMDAR encephalitis mice.
IGF2BP3-stabilized CAMK1 regulates the mitochondrial dynamics of renal tubule to alleviate diabetic nephropathy.
Ubiquitinome Analysis Uncovers Alterations in Synaptic Proteins and Glucose Metabolism Enzymes in the Hippocampi of Adolescent Mice Following Cold Exposure.
Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.
Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia-inducible factor-1α in normoxia.
Mechanistic of AMPK/ACC2 regulating myoblast differentiation by fatty acid oxidation of goat.
Imbalanced mitochondrial dynamics contributes to the pathogenesis of X-linked adrenoleukodystrophy.
Targeting DRP1 with Mdivi-1 to correct mitochondrial abnormalities in ADOA+ syndrome.
CIAO1 loss of function causes a neuromuscular disorder with compromise of nucleocytoplasmic Fe-S enzymes.
Decreasing mitochondrial fission ameliorates HIF-1α-dependent pathological retinal angiogenesis.
Mitochondria-Targeted Natural Antioxidant Nanosystem for Diabetic Vascular Calcification Therapy.
Acid Neutralization by Composite Lysine Nanoparticles for Spinal Cord Injury Recovery through Mitigating Mitochondrial Dysfunction.
Paeoniflorin Promotes Ovarian Development in Mice by Activating Mitophagy and Preventing Oxidative Stress.
Zearalenone modulates the function of goat endometrial cells via the mitochondrial quality control system.
Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury.
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
High-fat diet-induced L-saccharopine accumulation inhibits estradiol synthesis and damages oocyte quality by disturbing mitochondrial homeostasis.
MCT1-governed pyruvate metabolism is essential for antibody class-switch recombination through H3K27 acetylation.
Activation of Ca(2+) phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies.
NSD2 modulates Drp1-mediated mitochondrial fission in chronic renal allograft interstitial fibrosis by methylating STAT1.
Chronic Sleep Deprivation Impairs Visual Functions via Oxidative Damage in Mice.
ZNF746 plays cardinal roles on colorectal cancer (CRC) cell invasion and migration and regulates mitochondrial dynamics and morphological changes of CRC cells-Role of combined melatonin and 5-FU regimen.
Effects of metformin on glucose metabolism and mitochondrial function in patients with obstructive sleep apnea: A pilot randomized trial.
Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis.
Serine synthesis sustains macrophage IL-1β production via NAD(+)-dependent protein acetylation.
Mitochondrial dynamics disruption: Unraveling Dinotefuran's impact on cardiotoxicity.
Antrodia cinnamomea triterpenoids attenuate cardiac hypertrophy via the SNW1/RXR/ALDH2 axis.
Mesenchymal stem cell-loaded hydrogel to inhibit inflammatory reaction in surgical brain injury via mitochondria transfer.
Mitochondrial mechanotransduction through MIEF1 coordinates the nuclear response to forces.
Hyperglycemia-depleted glutamine contributes to the pathogenesis of diabetic corneal endothelial dysfunction.
Oleanonic acid ameliorates mutant Aβ precursor protein-induced oxidative stress, autophagy deficits, ferroptosis, mitochondrial damage, and ER stress in vitro.
Cardiomyocyte STIM1 downregulation exacerbates post-Myocardial Infarction remodeling by dysregulating mitochondrial ultrastructure and metabolic signaling.
Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia.
IDH1/MDH1 deacetylation promotes NETosis by regulating OPA1 and autophagy.
Myricetin Alleviates Silica-Mediated Lung Fibrosis via PPARγ-PGC-1α Loop and Suppressing Mitochondrial Senescence in Epithelial Cells.
Disturbance of mitochondrial dynamics led to spermatogenesis disorder in mice exposed to polystyrene micro- and nanoplastics.
Presenilin2 D439A Mutation Induces Dysfunction of Mitochondrial Fusion/Fission Dynamics and Abnormal Regulation of GTPase Activity.
Aldehyde Dehydrogenase 2 Deficiency Aggravates Lung Fibrosis through Mitochondrial Dysfunction and Aging in Fibroblasts.
The effects of the atrial natriuretic peptide deficiency on renal cortical mitochondrial bioenergetics in the Dahl SS rat.
Pathological characteristics of axons and alterations of proteomic and lipidomic profiles in midbrain dopaminergic neurodegeneration induced by WDR45-deficiency.
Nrf2 expression, mitochondrial fission, and neuronal apoptosis in the prefrontal cortex of methamphetamine abusers and rats.
Mfn2 induces NCLX-mediated calcium release from mitochondria.
The mechanism of extracellular CypB promotes glioblastoma adaptation to glutamine deprivation microenvironment.
VDR regulates mitochondrial function as a protective mechanism against renal tubular cell injury in diabetic rats.
Disturbance of mitochondrial dynamics in myocardium of broilers with pulmonary hypertension syndrome.
Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia-reperfusion injury.
Schisandrin B Alleviates LPS Induced Mitochondrial Damage in C28I2 Cells.
The NLRX1-SLC39A7 complex orchestrates mitochondrial dynamics and mitophagy to rejuvenate intervertebral disc by modulating mitochondrial Zn(2+) trafficking.
Mitochondrial dysfunction induced by HIF-1α under hypoxia contributes to the development of gastric mucosal lesions.
Moderate replacement of fish oil with palmitic acid-stimulated mitochondrial fusion promotes β-oxidation by Mfn2 interacting with Cpt1α via its GTPase-domain.
TMAO promotes vascular endothelial cell pyroptosis via the LPEAT-mitophagy pathway.
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Icaritin with autophagy/mitophagy inhibitors synergistically enhances anticancer efficacy and apoptotic effects through PINK1/Parkin-mediated mitophagy in hepatocellular carcinoma.
LonP1 Links Mitochondria-ER Interaction to Regulate Heart Function.
ShenQiWan ameliorates renal injury in type 2 diabetic mice by modulating mitochondrial fusion and endoplasmic reticulum stress.
Exercise prevents fatal stress-induced myocardial injury in obese mice.
Blockage of S100A8/A9 ameliorates septic nephropathy in mice.
Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.
Arsenic induced autophagy-dependent apoptosis in hippocampal neurons via AMPK/mTOR signaling pathway.
Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy.
Mitochondrial miR-12294-5p regulated copper-induced mitochondrial oxidative stress and mitochondrial quality control imbalance by targeted inhibition of CISD1 in chicken livers.
Paternal cadmium exposure affects estradiol synthesis by impairing intracellular cholesterol homeostasis and mitochondrial function in offspring female mice.
Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission.
Polydatin improves vascular endothelial function by maintaining mitochondrial homeostasis under high glucose conditions.
TCH-165 attenuates cardiac ischaemia/reperfusion injury by balancing mitochondrial dynamics via increasing proteasome activity.
Endoplasmic reticulum stress induced by turbulence of mitochondrial fusion and fission was involved in stressed cardiomyocyte injury.
FGD5-AS1/miR-5590-3p/PINK1 induces Lenvatinib resistance in hepatocellular carcinoma.
Schisandrin B Alleviates Renal Tubular Cell Epithelial-Mesenchymal Transition and Mitochondrial Dysfunction by Kielin/Chordin-like Protein Upregulation via Akt Pathway Inactivation and Adenosine 5'-Monophosphate (AMP)-Activated Protein Kinase Pathway Activation in Diabetic Kidney Disease.
Low-dose atorvastatin protects skeletal muscle mitochondria in high-fat diet-fed mice with mitochondrial autophagy inhibition and fusion enhancement.
Sodium Sulfite-Triggered Hepatocyte Ferroptosis via mtROS/Lysosomal Membrane Permeabilization-Mediated Lysosome Iron Efflux.
Alpha lipoamide inhibits diabetic kidney fibrosis via improving mitochondrial function and regulating RXRα expression and activation.
AdipoRon mitigates tau pathology and restores mitochondrial dynamics via AMPK-related pathway in a mouse model of Alzheimer's disease.
miR-27a-3p relieves heat stress-induced mitochondrial damage and aberrant milk protein synthesis through MEK/ERK pathway in BMECs.
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
miR-124-3p improves mitochondrial function of renal tubular epithelial cells in db/db mice.
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
Empagliflozin ameliorates cardiac dysfunction in heart failure mice via regulating mitochondrial dynamics.
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury.
MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model.
BNP protects against diabetic cardiomyopathy by promoting Opa1-mediated mitochondrial fusion via activating the PKG-STAT3 pathway.
Genetic deletion of skeletal muscle iPLA(2)γ results in mitochondrial dysfunction, muscle atrophy and alterations in whole-body energy metabolism.
High-fat diet causes mitochondrial damage and downregulation of mitofusin-2 and optic atrophy-1 in multiple organs.
RINT1 deficiency disrupts lipid metabolism and underlies a complex hereditary spastic paraplegia.
Bavachin and Corylifol A Improve Muscle Atrophy by Enhancing Mitochondria Quality Control in Type 2 Diabetic Mice.
N-acetyl-L-cysteine alleviates FUNDC1-mediated mitophagy by regulating mitochondrial dynamics in type 1 diabetic nephropathy canine.
Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF-κB pathway due to mitochondrial damage.
Adaptive exhaustion during prolonged intermittent hypoxia causes dysregulated skeletal muscle protein homeostasis.
Non-Lethal Concentrations of CdCl(2) Cause Marked Alternations in Cellular Stress Responses within Exposed Sertoli Cell Line.
Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation.
MiR-130a-3p regulates FUNDC1-mediated mitophagy by targeting GJA1 in myocardial ischemia/reperfusion injury.
Mitofusin 1 and 2 differentially regulate mitochondrial function underlying Ca(2+) signaling and proliferation in rat aortic smooth muscle cells.
SIRT3 promotes metabolic maturation of human iPSC-derived cardiomyocytes via OPA1-controlled mitochondrial dynamics.
SIRT3-dependent mitochondrial redox homeostasis mitigates CHK1 inhibition combined with gemcitabine treatment induced cardiotoxicity in hiPSC-CMs and mice.
Non-steroidal mineralocorticoid receptor antagonist finerenone ameliorates mitochondrial dysfunction via PI3K/Akt/eNOS signaling pathway in diabetic tubulopathy.
BNIP3 overexpression may promote myeloma cell apoptosis by enhancing sensitivity to bortezomib via the p38 MAPK pathway.
Zearalenone promotes porcine ESCs apoptosis by enhancing Drp1-mediated mitochondrial fragmentation and activating the JNK pathway.
Lactate Mediates High-Intensity Interval Training-Induced Promotion of Hippocampal Mitochondrial Function through the GPR81-ERK1/2 Pathway.
Ramelteon attenuates renal ischemia and reperfusion injury through reducing mitochondrial fission and fusion and inflammation.
The Binding of HSPA8 and Mitochondrial ALDH2 Mediates Oxygen-Glucose Deprivation-Induced Fibroblast Senescence.
The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cells.
Inhibition of the lncRNA 585189 prevents podocyte injury and mitochondria dysfunction by promoting hnRNP A1 and SIRT1 in diabetic nephropathy.
Ubiquitination of Ku70 by Parkin promotes apoptosis of lens epithelial cells.
Phospholipase A2-activating protein induces mitophagy through anti-apoptotic MCL1-mediated NLRX1 oligomerization.
Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease.
Diosgenin Targets CaMKK2 to Alleviate Type II Diabetic Nephropathy through Improving Autophagy, Mitophagy and Mitochondrial Dynamics.
Correction: Tang et al. Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop. Nutrients 2022, 14, 1504.
LDLR heterozygous deletion reduces hamster testicular cholesterol toxicity via AMPK/Sirt1/PGC-1α pathway.
Aristolochic acid I exposure triggers ovarian dysfunction by activating NLRP3 inflammasome and affecting mitochondrial homeostasis.
Mitochondrial division inhibitor (mdivi-1) inhibits proliferation and epithelial-mesenchymal transition via the NF-κB pathway in thyroid cancer cells.
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction.
HIGD2A silencing impairs hepatocellular carcinoma growth via inhibiting mitochondrial function and the MAPK/ERK pathway.
Molybdenum and Cadmium Co-induce Mitochondrial Quality Control Disorder via FUNDC1-Mediated Mitophagy in Sheep Kidney.
Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2.
Blockage of Fibronectin 1 Ameliorates Myocardial Ischemia/Reperfusion Injury in Association with Activation of AMP-LKB1-AMPK Signaling Pathway.
Rhein Ameliorates Cognitive Impairment in an APP/PS1 Transgenic Mouse Model of Alzheimer's Disease by Relieving Oxidative Stress through Activating the SIRT1/PGC-1α Pathway.
Appropriate Dose of Dapagliflozin Improves Cardiac Outcomes by Normalizing Mitochondrial Fission and Reducing Cardiomyocyte Apoptosis After Acute Myocardial Infarction.
Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.
Mitochonic Acid-5 Inhibits Reactive Oxygen Species Production and Improves Human Chondrocyte Survival by Upregulating SIRT3-Mediated, Parkin-dependent Mitophagy.
Atorvastatin Restores PPARα Inhibition of Lipid Metabolism Disorders by Downregulating miR-21 Expression to Improve Mitochondrial Function and Alleviate Diabetic Nephropathy Progression.
Grape seed proanthocyanidin extract targets p66Shc to regulate mitochondrial biogenesis and dynamics in diabetic kidney disease.
COA3 overexpression promotes non-small cell lung cancer metastasis by reprogramming glucose metabolism.
Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.
Scutellarin Protects Against Mitochondrial Reactive Oxygen Species-Dependent NLRP3 Inflammasome Activation to Attenuate Intervertebral Disc Degeneration.
Mitoquinone mitigates paraquat-induced A549 lung epithelial cell injury by promoting MFN1/MFN2-mediated mitochondrial fusion.
Battery wastewater induces nephrotoxicity via disordering the mitochondrial dynamics.
Mannose inhibits the growth of prostate cancer through a mitochondrial mechanism.
Protective Effect of Manganese on Apoptosis and Mitochondrial Function of Heat-Stressed Primary Chick Embryonic Myocardial Cells.
UBXD8 mediates mitochondria-associated degradation to restrain apoptosis and mitophagy.
Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF.
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats.
Integrated Analysis of Transcriptome and microRNA Profile Reveals the Toxicity of Euphorbia Factors toward Human Colon Adenocarcinoma Cell Line Caco-2.
Anti-ANGPTL3-FLD monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage.
Cadmium-induced apoptosis of Leydig cells is mediated by excessive mitochondrial fission and inhibition of mitophagy.
Diosgenin Ameliorated Type II Diabetes-Associated Nonalcoholic Fatty Liver Disease through Inhibiting De Novo Lipogenesis and Improving Fatty Acid Oxidation and Mitochondrial Function in Rats.
COX7A1 enhances the sensitivity of human NSCLC cells to cystine deprivation-induced ferroptosis via regulating mitochondrial metabolism.
O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.
Gestational Intermittent Hypoxia Induces Mitochondrial Impairment in the Geniohyoid Muscle of Offspring Rats.
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.
Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway.
HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3.
Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.
The effect of mitochondrial fusion on chondrogenic differentiation of cartilage progenitor/stem cells via Notch2 signal pathway.
Carbon tetrachloride induced mitochondrial division, respiratory chain damage, abnormal intracellular [H(+)] and apoptosis are due to the activation of 5-HT degradation system in hepatocytes.
Autophagy and mitochondrial dynamics contribute to the protective effect of diosgenin against 3-MCPD induced kidney injury.
Long-term exercise pre-training attenuates Alzheimer's disease-related pathology in a transgenic rat model of Alzheimer's disease.
A possible new activator of PI3K-Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction.
ManNAc protects against podocyte pyroptosis via inhibiting mitochondrial damage and ROS/NLRP3 signaling pathway in diabetic kidney injury model.
Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.
Heterozygous PRKN mutations are common but do not increase the risk of Parkinson's disease.
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Identification of Mitofusin 1 and Complement Component 1q Subcomponent Binding Protein as Mitochondrial Targets in Systemic Lupus Erythematosus.
The mitochondrial protein Sideroflexin 3 (SFXN3) influences neurodegeneration pathways in vivo.
Targeting Tau Mitigates Mitochondrial Fragmentation and Oxidative Stress in Amyotrophic Lateral Sclerosis.
Herceptin induces ferroptosis and mitochondrial dysfunction in H9c2 cells.
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
Attenuates of NAD(+) impair BMSC osteogenesis and fracture repair through OXPHOS.
Protein C receptor maintains cancer stem cell properties via activating lipid synthesis in nasopharyngeal carcinoma.
Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.
Cdk5 Promotes Mitochondrial Fission via Drp1 Phosphorylation at S616 in Chronic Ethanol Exposure-Induced Cognitive Impairment.
GABA regulates IL-1β production in macrophages.
Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function.
Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD(+) regeneration in KRas-mutant lung adenocarcinoma.
HIF-1α mediates renal fibrosis by regulating metabolic remodeling of renal tubule epithelial cells.
A pivotal role of selective autophagy in mitochondrial quality control: Implications for zinc oxide nanoparticles induced neurotoxicity.
Reduced VDAC1, Maintained Mitochondrial Dynamics and Enhanced Mitochondrial Biogenesis in a Transgenic Tau Mouse Model of Alzheimer's Disease.
Baicalein suppresses high glucose-induced inflammation and apoptosis in trophoblasts by targeting the miRNA-17-5p-Mfn1/2-NF-κB pathway.
Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.
Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress.
Phosphorylation of Dynamin-Related Protein 1 (DRP1) Regulates Mitochondrial Dynamics and Skeletal Muscle Wasting in Cancer Cachexia.
Mitochondrial Fusion Potentially Regulates a Metabolic Change in Tibetan Chicken Embryonic Brain During Hypoxia.
Vanadium Induces Oxidative Stress and Mitochondrial Quality Control Disorder in the Heart of Ducks.
Secreted Frizzled-Related Protein 5 Protects Against Cardiac Rupture and Improves Cardiac Function Through Inhibiting Mitochondrial Dysfunction.
Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats.
RNA-Seq Profiling to Investigate the Mechanism of Qishen Granules on Regulating Mitochondrial Energy Metabolism of Heart Failure in Rats.
Mitochondrial Transplantation Attenuates Cerebral Ischemia-Reperfusion Injury: Possible Involvement of Mitochondrial Component Separation.
Maresin 1 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury via Inhibiting NOX4/ROS/NF-κB Pathway.
Tortoise Plastron and Deer Antler Gelatin Prevents Against Neuronal Mitochondrial Dysfunction In Vitro: Implication for a Potential Therapy of Alzheimer's Disease.
Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes.
Elevated Lactate by High-Intensity Interval Training Regulates the Hippocampal BDNF Expression and the Mitochondrial Quality Control System.
The E3 ubiquitin ligase TRIM31 is involved in cerebral ischemic injury by promoting degradation of TIGAR.
Punicalagin Protects Against Diabetic Cardiomyopathy by Promoting Opa1-Mediated Mitochondrial Fusion via Regulating PTP1B-Stat3 Pathway.
Trimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control.
Mechanisms of impaired mitochondrial homeostasis and NAD(+) metabolism in a model of mitochondrial heart disease exhibiting redox active iron accumulation.
Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca(2+) homeostasis.
SIRT3 protects bovine mammary epithelial cells from heat stress damage by activating the AMPK signaling pathway.
Melatonin protects against excessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells.
Anti-inflammatory and neuroprotective effects of natural cordycepin in rotenone-induced PD models through inhibiting Drp1-mediated mitochondrial fission.
The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses.
LACTB suppresses melanoma progression by attenuating PP1A and YAP interaction.
Mitocytosis, a migrasome-mediated mitochondrial quality-control process.
Conditioned medium from induced pluripotent stem cell-derived mesenchymal stem cells accelerates cutaneous wound healing through enhanced angiogenesis.
AMPK-dependent and -independent coordination of mitochondrial function and muscle fiber type by FNIP1.
Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
Vmp1, Vps13D, and Marf/Mfn2 function in a conserved pathway to regulate mitochondria and ER contact in development and disease.
Mesenchymal stem cells ameliorate lipid metabolism through reducing mitochondrial damage of hepatocytes in the treatment of post-hepatectomy liver failure.
Cdk5-Mediated Phosphorylation of Sirt1 Contributes to Podocyte Mitochondrial Dysfunction in Diabetic Nephropathy.
CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson's disease.
OPA1 haploinsufficiency due to a novel splicing variant resulting in mitochondrial dysfunction without mitochondrial DNA depletion.
Nanoparticle-encapsulated antioxidant improves placental mitochondrial function in a sexually dimorphic manner in a rat model of prenatal hypoxia.
Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner.
Caffeine promotes angiogenesis through modulating endothelial mitochondrial dynamics.
Possible relationship between mitochondrial changes and oxidative stress under low dose-rate irradiation.
Entresto protected the cardiomyocytes and preserved heart function in cardiorenal syndrome rat fed with high-protein diet through regulating the oxidative stress and Mfn2-mediated mitochondrial functional integrity.
USP30-AS1 contributes to mitochondrial quality control in glioblastoma cells.
Targeting P2RX1 alleviates renal ischemia/reperfusion injury by preserving mitochondrial dynamics.
LKB1/AMPKα signaling pathway and mitochondrial fission/fusion dynamics regulate apoptosis induced by 3-chlorpropane-1,2-diol in HEK293 cells.
Extract of Cynomorium songaricum ameliorates mitochondrial ultrastructure impairments and dysfunction in two different in vitro models of Alzheimer's disease.
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
Mst1 Knockout Alleviates Mitochondrial Fission and Mitigates Left Ventricular Remodeling in the Development of Diabetic Cardiomyopathy.
Deletion of Bmal1 Impairs Pancreatic β-Cell Function via Mitochondrial Signaling Pathway.
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
A Long-Term Enriched Environment Ameliorates the Accelerated Age-Related Memory Impairment Induced by Gestational Administration of Lipopolysaccharide: Role of Plastic Mitochondrial Quality Control.
Drp1-dependent mitochondrial fission contributes to Cr(VI)-induced mitophagy and hepatotoxicity.
PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth.
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.
Nestin protects podocyte from injury in lupus nephritis by mitophagy and oxidative stress.
AIM2 promotes the development of non-small cell lung cancer by modulating mitochondrial dynamics.
NAD(+) precursor modulates post-ischemic mitochondrial fragmentation and reactive oxygen species generation via SIRT3 dependent mechanisms.
Mitochondrial Dynamics Regulation in Skin Fibroblasts from Mitochondrial Disease Patients.
Fluoride-induced renal dysfunction via respiratory chain complex abnormal expression and fusion elevation in mice.
Anti-insulin resistance effects of salidroside through mitochondrial quality control.
Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice.
Sodium-glucose cotransporter 2 inhibition attenuates protein overload in renal proximal tubule via suppression of megalin O-GlcNacylation in progressive diabetic nephropathy.
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
Fission and fusion machineries converge at ER contact sites to regulate mitochondrial morphology.
DsbA-L deficiency exacerbates mitochondrial dysfunction of tubular cells in diabetic kidney disease.
Propofol Ameliorates H9c2 Cells Apoptosis Induced by Oxygen Glucose Deprivation and Reperfusion Injury via Inhibiting High Levels of Mitochondrial Fusion and Fission.
OPA1 overexpression ameliorates mitochondrial cristae remodeling, mitochondrial dysfunction, and neuronal apoptosis in prion diseases.
Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae.
Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model.
Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.
Arsenic-induced cardiotoxicity correlates with mitochondrial damage and trace elements imbalance in broiler chickens.
Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3-dependent mechanism in male mice.
CDDO-Me Selectively Attenuates CA1 Neuronal Death Induced by Status Epilepticus via Facilitating Mitochondrial Fission Independent of LONP1.
Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson's disease.
Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells.
UBIAD1 protects against oxygen-glucose deprivation/reperfusion-induced multiple subcellular organelles injury through PI3K/AKT pathway in N2A cells.
In Vivo Deletion of β-Cell Drp1 Impairs Insulin Secretion Without Affecting Islet Oxygen Consumption.
Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer's disease.
Pro-Inflammatory CXCR3 Impairs Mitochondrial Function in Experimental Non-Alcoholic Steatohepatitis.
Exercise Combined with Rhodiola sacra Supplementation Improves Exercise Capacity and Ameliorates Exhaustive Exercise-Induced Muscle Damage through Enhancement of Mitochondrial Quality Control.
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
Low-level laser therapy for beta amyloid toxicity in rat hippocampus.
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Antagonistic effects of selenium on cadmium-induced apoptosis by restoring the mitochondrial dynamic equilibrium and energy metabolism in chicken spleens.
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis.
Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization.
Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology.
Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
Porcine reproductive and respiratory syndrome virus triggers mitochondrial fission and mitophagy to attenuate apoptosis.
Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice.
MARCH5-mediated quality control on acetylated Mfn1 facilitates mitochondrial homeostasis and cell survival.
Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart.
Mitofusin 1 is degraded at G2/M phase through ubiquitylation by MARCH5.
Li N, Ma D, Luo S, He A, Chang S
Mediators of inflammation 2026;2026:7600668
Mediators of inflammation 2026;2026:7600668
Chronic intermittent hypoxia increases Parkinson's disease susceptibility via PPARα-mediated lipid droplet-mitochondrial dysfunction.
Zhai MR, Pan J, Wu ZH, He YY, Zhang KR, Ren L, Wang YR, Li YB, Gao J, Xiao L, Liu YH
Theranostics 2026;16(5):2466-2487
Theranostics 2026;16(5):2466-2487
Curcumin augments mitophagy via Nrf2-PINK1-mediated, Parkin-dependent ubiquitination to suppress ferroptosis in post-cardiac arrest brain injury.
Li Z, Xu W, Ren S, Zheng Q, Xing J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158035
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158035
Reproductive toxicity mechanisms of PNMC: Evidence from mitochondrial dysfunction and hormone synthesis disruption in the KGN cells.
Xie J, Pan Z, Du Y, Li K, Liu Y, Weng Q, Zhang H
Reproductive toxicology (Elmsford, N.Y.) 2026 May;142:109223
Reproductive toxicology (Elmsford, N.Y.) 2026 May;142:109223
The purinergic receptor P2rx7 mediated ATP sensing is required to prevent bone aging by directing mitochondrial fitness of MSCs.
Zhuang Z, Han C, Cai M, Li M, Lin S, Chen L, Zhu Z, Zhang H, Xing C, Han B, Yang R
Journal of advanced research 2026 Mar;81:349-364
Journal of advanced research 2026 Mar;81:349-364
Effects of local skeletal muscle cooling prior to acute exercise and endurance training on mitochondrial adaptation in mice.
Kano R, Kusano T, Ando T, Takeda R, Natsuyama R, Takagi R, Poole DC, Kano Y, Hoshino D
The journal of physiological sciences : JPS 2026 Mar;76(1):100059
The journal of physiological sciences : JPS 2026 Mar;76(1):100059
Targeting NME3 to Restore Mitochondrial Fission-Fusion Balance Defines a Novel Disease-Modifying Strategy for Parkinson's Disease.
Qiao C, Hu XQ, Xu SH, Yao MF, Liu JP, Cao L
CNS neuroscience & therapeutics 2026 Mar;32(3):e70822
CNS neuroscience & therapeutics 2026 Mar;32(3):e70822
Fibroblast growth factor-inducible 14 accelerates pulmonary fibrosis by inducing fibroblast senescence in mice.
Guan XX, Zhong WJ, Tang WF, Liu YB, Chen MR, Li JL, Zhang CY, Zhou Y, Guan CX, Wu JN, Ma L, Duan JX
Cellular and molecular life sciences : CMLS 2026 Mar 6;83(1)
Cellular and molecular life sciences : CMLS 2026 Mar 6;83(1)
Intermittent fasting attenuates ovarian chronic inflammation in obese mice by inhibiting the CXCL12-CXCR4 axis.
Chen X, Han Z, Yu X, Hao X
International immunopharmacology 2026 Jun 15;179:116603
International immunopharmacology 2026 Jun 15;179:116603
Sennoside A alleviates HFD-induced MAFLD by protecting intestinal barrier function through TLR4/NF-κB and mitochondrial quality control.
Ma L, Yuan C, Cao X, Sun Y
Pathology, research and practice 2026 Jul;283:156482
Pathology, research and practice 2026 Jul;283:156482
YAP in synovial macrophages mitigates mechanically-induced osteoarthritis by preserving mitochondrial fusion.
Cheng Y, Guo ZL, Gu YF, Li WL, Zhang WB
Cellular signalling 2026 Jul;143:112430
Cellular signalling 2026 Jul;143:112430
Mitochondrial fission process 1 is required for bovine oocyte maturation through regulation of mitochondrial function and dynamics.
Han T, Zhao Y, Sun Z, Jiao A, Wang B, Gao Q
Theriogenology 2026 Jul 15;259:117916
Theriogenology 2026 Jul 15;259:117916
Overexpression of mitofusin 2 ameliorates inflammation and oxidative stress in lipopolysaccharide-induced mastitis model by regulating phosphofurin acidic cluster sorting protein 2.
Zhou X, Zhang Y, Ma H, Fu S, Liu J, Guo W, Tian X, Huang B
Animal models and experimental medicine 2026 Jan;9(1):154-167
Animal models and experimental medicine 2026 Jan;9(1):154-167
The Neuroprotective Role of Ginsenoside Rg1 Against Cerebral Ischemia-Reperfusion Damage Through Inhibition of Mitophagy via Blocking Mitophagosome-Lysosome Fusion.
Ai L, Ren H, Wang Y, Liu M, Qiu Y, Feng J, Dai R, Fu W, Wang Y, Xi Z, Xu H, Wang F
Cell proliferation 2026 Jan;59(1):e70071
Cell proliferation 2026 Jan;59(1):e70071
Lobetyolin alleviates microglial inflammation by activating CK2α/Opa1-mediated mitochondrial fusion in ischemic stroke.
Qin N, Liu R, Deng R, Jia W, Yang Y, Sun J, Gao S, Zhu T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157651
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157651
Nobiletin Ameliorates Skeletal Muscle Performance in D-Galactose-Induced Aging Mice by Boosting Aerobic Metabolism.
Wang H, Zhang Y, Zhang Y, Wang X, Li Y, Ren F, Sun Y
Food science & nutrition 2026 Jan;14(1):e71416
Food science & nutrition 2026 Jan;14(1):e71416
Stress-induced mitochondrial fragmentation in endothelial cells disrupts blood-retinal barrier integrity causing neurodegeneration.
Cueva Vargas JL, Belforte N, Vidal-Paredes IA, Dotigny F, Vande Velde C, Quintero H, Di Polo A
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Jan 7;34(1):562-581
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Jan 7;34(1):562-581
Macelignan, a lignan from Myristica fragrans Houtt., rescues mitochondrial homeostasis and prevents cognitive decline in vascular dementia by modulating the mTOR-Mitophagy axis.
Qi Z, Chu X, Li S, Bai Q, Ding N, Yan G, Yu H, Cui C
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120603
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120603
Endoplasmic Reticulum Stress Induced by Turbulence of Mitochondrial Fusion and Fission Was Involved in Isoproterenol-Induced H9c2 Cell Injury.
Zhang S, Chen L, Jia F, Zhang S, Zhang H, Shi W, Cong B
International journal of molecular sciences 2026 Jan 30;27(3)
International journal of molecular sciences 2026 Jan 30;27(3)
The UBC/SIRT5/DRP1 axis regulates mitochondrial dynamics to alleviate Staphylococcus aureus-induced oxidative stress and senescence in bovine mammary epithelial cells.
Hu H, Jiang N, Liu J, Bi J, Liu X, Xu B, Cao Y, Guo W, Fu S
PLoS pathogens 2026 Feb;22(2):e1013975
PLoS pathogens 2026 Feb;22(2):e1013975
Mesenchymal Stem Cell-derived Exosomes Alleviate Oxidative Stress and Brain Injuries Through Promoting OPA1 Mediated Mitochondrial Fusion After Intracerebral Hemorrhage.
Xu Y, Du Y, Hu Q, Wang P, Cai Y, Zhou G, Liu H, Guo W
Molecular neurobiology 2026 Feb 7;63(1):426
Molecular neurobiology 2026 Feb 7;63(1):426
PM(10) Disrupts Mitochondrial Homeostasis in Corneal Epithelial Cells: Protective Effects of SKQ1.
Somayajulu M, Wright R, Muhammed FS, McClellan SA, Ibrahim AS, Hazlett LD
Antioxidants (Basel, Switzerland) 2026 Feb 25;15(3)
Antioxidants (Basel, Switzerland) 2026 Feb 25;15(3)
TRPV4 Deficiency Shifts Mitochondrial Dynamics Toward a Fragmented Morphology in Primary Microglia.
Burlacu EA, Schellingen R, Moya-Gómez A, Verberk SGS, Stas N, Kessels S, Alpizar YA, Rigo JM, Bronckaers A, Hendriks JJA, Faes C, Brône B
Cells 2026 Feb 13;15(4)
Cells 2026 Feb 13;15(4)
Trimethylamine-N-oxide disrupts spermatogenesis by inducing mitochondrial oxidative stress injury through Hippo signaling.
Wang S, Ma G, Qi C, Cheng S, Lai H, Zhou L, Wu G, Chen Z, Mao X, Jing T, He Y, Zhou H
Free radical biology & medicine 2026 Feb 1;243:452-465
Free radical biology & medicine 2026 Feb 1;243:452-465
Hippocampal HDAC7 induces perioperative neurocognitive disorders via an NF-κB-MFN2-ACSL4 ferroptosis pathway.
Guo J, Chi W, Zhang K, Huang Y, Zhang B, Guo X, Meng F
Cellular signalling 2026 Aug;144:112531
Cellular signalling 2026 Aug;144:112531
Mitochondrial TRPV1 exacerbates cognitive deficits in sepsis-associated encephalopathy by driving microglial metabolic reprogramming.
Fan Z, Du L, Yin L, Liu H, Li M, Li J, Liu F, Yang L, Li J, Wang Q, Wu Y, Ma H, Zhang X
Free radical biology & medicine 2026 Apr;247:448-468
Free radical biology & medicine 2026 Apr;247:448-468
Di-(2-Ethylhexyl) phthalate causes testicular ferroptosis though deficiency of androgen receptor and disruption of mitochondrial quality control.
Tian Q, Yan X, Xu J, Ma J, Sun X, Li J, Wang N, Yao X, Qiu T, Zhang C, Deng H, Yang G
Free radical biology & medicine 2026 Apr;247:348-360
Free radical biology & medicine 2026 Apr;247:348-360
Brain and Liver Dual-Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy.
Gong W, Hui W, Qiao S, Ji Q, Liu M, Zhang B, Liu D, Wu Y, Zhou S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 7;:e23458
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 7;:e23458
Florfenicol impairs steroid hormone secretion in bovine ovarian granulosa cells: Involvement of the cAMP/PKA/StAR signaling pathway and oxidative stress.
Zhao J, Zhou X, You B, Cheng B, Hu J, Lu Y, Xu D, Zhang X, Yan C, Gao Q, Liu H, Jin Q
Theriogenology 2026 Apr 23;261:117956
Theriogenology 2026 Apr 23;261:117956
The Role of Placental MFF-Mediated Mitochondrial Fission in Gestational Diabetes Mellitus.
Wei L, Fang C, Jiang Y, Zhang H, Gao P, Zhou X, Zhu S, Du Y, Su R, Guo L, He M, Wang S, Feng L, Yu J
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:541-554
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:541-554
Metformin Activation of Sirtuin 3 Signaling Regulates Mitochondrial Function Improves Diabetes-Associated Cognitive Impairment.
An JF, Su H, Zhang CQ, Wang XT, Zhang GQ, Fu LY, Xu YN, Tao L, Shen XC
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:2317-2330
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:2317-2330
Silencing ATF3 mediates mitochondrial homeostasis and improves ischemic stroke through regulating the MAPK signaling pathway.
Li H, Zhang F, Zhang C, Zhou M, Liu Q, Zeng G
Frontiers in molecular neuroscience 2025;18:1554802
Frontiers in molecular neuroscience 2025;18:1554802
MFN2-a multifaceted guardian against Parkinson's pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.
Cheng Y, Zhai H, Liu Y, Yang Y, Fang B, Song M, Wang X, Zhong P
Frontiers in aging neuroscience 2025;17:1611958
Frontiers in aging neuroscience 2025;17:1611958
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis.
Zhao S, Chen R, An Y, Zhang Y, Ma C, Gao Y, Lu Y, Yang F, Bai X, Zhang J
Frontiers in aging neuroscience 2025;17:1522073
Frontiers in aging neuroscience 2025;17:1522073
Bavachin suppresses proliferation of laryngopharyngeal cancer by regulating the STAT3 and MAPK signaling pathways.
Yang X, Ding Z, Hua H, Gan R, Meng D, Zang Y, Xiao H, Wang D, Jiang W, Si D, Wei X, Zhang M, Zhang H, Gao C
Journal of Cancer 2025;16(7):2339-2352
Journal of Cancer 2025;16(7):2339-2352
Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.
Chen Y, Shimoda N, Nihei CI, Sawa R, Takahashi Y, Nishigori M, Nakamura S, Liu J, Koshiba T, Ushio-Watanabe N, Nishikawa Y
Frontiers in immunology 2025;16:1408992
Frontiers in immunology 2025;16:1408992
1,25(OH)(2)D(3) up-regulated mitochondrial dynamics and biogenesis to modulate steroidogenesis in the scent glands of muskrats (Ondatra zibethicus).
Gao Q, Shi K, Shi X, Liu Y, Zhang H, Weng Q
The Journal of steroid biochemistry and molecular biology 2025 Sep;252:106787
The Journal of steroid biochemistry and molecular biology 2025 Sep;252:106787
Mechanism of mitofusin 2, mitochondria-associated membrane, and the mitochondrial pathway in alleviating oxidative stress and cell senescence in bovine mammary epithelial cells.
Hu H, Liu J, Yin J, Hu G, Huang B, Tu L, Liu X, Xu B, Cao Y, Guo W, Fu S
Journal of dairy science 2025 Sep;108(9):10151-10172
Journal of dairy science 2025 Sep;108(9):10151-10172
Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway.
Zhang T, Lv H, Jia S, Wang L, Liu W, Ding K, Du X, Hou G, Hou Z, Zhang Y, Zou W, Chen W, Zhu Y
Bone research 2025 Sep 24;13(1):79
Bone research 2025 Sep 24;13(1):79
Kaempferol improves mitochondrial homeostasis via mitochondrial dynamics and mitophagy in diabetic kidney disease.
Xia C, Zhang J, Chen H, Jiang W, Zhou S, Zheng H, Sun W
International immunopharmacology 2025 Sep 23;162:115121
International immunopharmacology 2025 Sep 23;162:115121
Sex-specific impact of selective reduced uterine placental perfusion model of preeclampsia on fetal cardiac maturation and mitochondrial function.
Chatterjee P, Molberg R, Kirschenman R, Holody CD, Quon A, Spaans F, Bourque SL, Lemieux H, Davidge ST
American journal of physiology. Regulatory, integrative and comparative physiology 2025 Sep 1;329(3):R474-R486
American journal of physiology. Regulatory, integrative and comparative physiology 2025 Sep 1;329(3):R474-R486
Gestational zearalenone causes fetal intrauterine growth restriction partially through deriving ROS-Drp1 mediated placental PANoptosis.
Liu JR, Wu FN, Lin S, Chen C, Liu Y, Fan JW, Hong Q, Chen YH
Ecotoxicology and environmental safety 2025 Sep 1;302:118636
Ecotoxicology and environmental safety 2025 Sep 1;302:118636
Porcine GWAS identifies ACOT11 as regulator for macrophage IL-1β maturation via IFNGR2 palmitoylation.
Zhang M, Liu S, Wu Z, Wang C, Zhang H, Yang J, Guo C, Dai M, Wang X, Ren W
Science China. Life sciences 2025 Oct;68(10):3037-3050
Science China. Life sciences 2025 Oct;68(10):3037-3050
Oxytocin Regulated Neuroinflammation through OTR/Mitochondria Mediated Pathway to Improve Hypoxia-Induced Brain Injury.
Yang X, Li K, Chen L, Wang L, Wang X, Lu K, Bai Y, Hou Y, Hou J, Wang C, Cheng X, Oldam J, Yu J, Wu J, Sun B
Molecular neurobiology 2025 Oct;62(10):12907-12923
Molecular neurobiology 2025 Oct;62(10):12907-12923
Skeletal Muscle PGC-1α Remodels Mitochondrial Phospholipidome but Does Not Alter Energy Efficiency for ATP Synthesis.
Karasawa T, Choi RH, Meza CA, Watanabe S, Maschek JA, Nikolova LS, Cox JE, Funai K
Journal of cachexia, sarcopenia and muscle 2025 Oct;16(5):e70090
Journal of cachexia, sarcopenia and muscle 2025 Oct;16(5):e70090
PPP1R3G inhibition impairs OPCs differentiation and myelination in aged mice.
Feng ZW, Miao X, Shi H, Zhang C, Wang G, Ding YN, Shi KX, Tang ZM, Yao RQ, Liu HY
International immunopharmacology 2025 Oct 30;164:115365
International immunopharmacology 2025 Oct 30;164:115365
MTCH2 modulates CPT1 activity to regulate lipid metabolism of adipocytes.
Wu C, Wang T, Ghosh A, Long F, Sharma AK, Dahlby T, Noé F, Severi I, Colleluori G, Cinti S, Giordano A, Ding L, Khandelwal R, Kostidis S, Giera M, Balazova L, Gardeux V, Abu-Nawwas L, Deplancke B, Chourasia S, Kleiner S, Hamilton BS, Alcántara JMA, Ruiz JR, Blüher M, Pekcec A, Balaz M, Gross A, Neubauer H, Wolfrum C
Nature communications 2025 Oct 3;16(1):8831
Nature communications 2025 Oct 3;16(1):8831
Luteoloside alleviates bleomycin-induced pulmonary fibrosis in mice via SIRT1-mediated protective effect against alveolar epithelial cell senescence.
Deng L, Sun B, Xia J, Zhuo W, Jiang M, Yin S, Yang F
Scientific reports 2025 Oct 29;15(1):37837
Scientific reports 2025 Oct 29;15(1):37837
Atrazine-induced hippocampal neurotoxicity: Involvement of Drp1-mediated mitochondrial fission.
Yang J, Qi L, Zhang C, Ding R, Bi H, Li P, Qi Z, Niu Q, Song W, Li J
Chemico-biological interactions 2025 Oct 22;420:111676
Chemico-biological interactions 2025 Oct 22;420:111676
Electroacupuncture improves motor function after ischemic stroke via regulating mitochondrial dynamics.
Li Z, Ji X, Wang X, Wang J, Lin R, Ma X, Zhang Q, Liang S
Brain research bulletin 2025 Nov;232:111599
Brain research bulletin 2025 Nov;232:111599
AMPK impairment caused by gelatin disturbs mitochondrial dynamics leading to enhanced phagocytosis of bacteria in PMA-stimulated U937 cells.
Chen K, Sun X, Feng Y, Jiang S, Hayashi T, Itoh K, Mizuno K, Hattori S, Fujisaki H, Liu W, Ikejima T
Cellular signalling 2025 Nov;135:111985
Cellular signalling 2025 Nov;135:111985
Mfn2 Regulates Scleral Remodeling in Myopia by Maintaining Endoplasmic Reticulum Homeostasis in Scleral Fibroblasts.
Wang Y, Liu S, Huang Q, Cheng Y
Investigative ophthalmology & visual science 2025 Nov 3;66(14):40
Investigative ophthalmology & visual science 2025 Nov 3;66(14):40
TAAR1 deficiency impairs mitochondrial dynamics and synaptic integrity in the medial prefrontal cortex and associated cognition in mice.
Zhang XQ, Xiong J, Liu DN, Zhang CC, Zhang Y, Li JT, Si TM, Su YA
Translational psychiatry 2025 Nov 21;15(1):490
Translational psychiatry 2025 Nov 21;15(1):490
MYC affects mitochondrial function in IgA nephropathy by promoting the degradation of MFN1 through HRD1.
Wu X, Liu L, Zhao R, Chen W
Immunologic research 2025 Nov 15;73(1):166
Immunologic research 2025 Nov 15;73(1):166
Leucokinin VIII acetate mitigates asthma severity by targeting ADCK5-induced cellular senescence.
Feng L, Zhong Y, Li L, Zhang M, Zhu M, Wang J, Huang M, Ji N, Ma Y
International immunopharmacology 2025 Nov 14;165:115426
International immunopharmacology 2025 Nov 14;165:115426
Cisplatin transported by COX17 induces cochlear damage by binding Myosin IIA to regulate cell pyroptosis induced by mitochondrial dysfunction.
Peng J, Tao G, Chen X, Ai Y, Lai R, Liu W, Hu B, Xu Y, Xie B, Li L
Life sciences 2025 Nov 1;380:123961
Life sciences 2025 Nov 1;380:123961
Effect of disruption of mitochondrial and endoplasmic reticulum calcium homeostasis on neurites in hydrogen peroxide- and ionomycin-treated cells.
Hoga K, Wakuzawa M, Nakamura T, Kato Y, Fukui K
Journal of clinical biochemistry and nutrition 2025 May;76(3):253-263
Journal of clinical biochemistry and nutrition 2025 May;76(3):253-263
Protective effect of astragaloside IV against zinc oxide nanoparticles induced human neuroblastoma SH-SY5Y cell death: a focus on mitochondrial quality control.
Wang L, Zhang L, Yun Y, Liang T, Yan C, Mao Z, Zhang J, Liu B, Zhang J, Liang T
Molecular and cellular biochemistry 2025 May;480(5):3079-3095
Molecular and cellular biochemistry 2025 May;480(5):3079-3095
The effect of Hydrogen-rich water on retinal degeneration in the outer nuclear layer of simulated weightlessness rats.
Mu Y, Li W, Wei D, Zhang X, Yao L, Xu X, Wang X, Zhang Z, Chen T
Life sciences in space research 2025 May;45:158-169
Life sciences in space research 2025 May;45:158-169
Kirenol alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the CK2/AKT pathway.
Zhang Y, Ye Y, Feng Y, Li X, Chen L, Zou X, Yan G, Chen Y, Nan L, Xu W, Chen L, Li H
Free radical biology & medicine 2025 May;232:353-366
Free radical biology & medicine 2025 May;232:353-366
Trehalose attenuates testicular aging by activating autophagy and improving mitochondrial quality.
Xi H, Shan W, Li M, Wang Z, Li Y
Andrology 2025 May;13(4):911-920
Andrology 2025 May;13(4):911-920
Instant fluorescence lifetime imaging microscopy reveals mechano-metabolic reprogramming of stromal cells in breast cancer peritumoral microenvironments.
Najera J, Chen H, Batista B, Ketchum F, Ali A, Zorlutuna P, Howard S, Datta M
bioRxiv : the preprint server for biology 2025 May 30;
bioRxiv : the preprint server for biology 2025 May 30;
Overexpression of c-Myc triggers p62 aggregation-mediated mitochondrial mitophagy in cabozantinib resistance of hepatocellular carcinoma.
Yang K, Zhang X, Yang K, Liu S, Zhang J, Fu Y, Liu T, Wu K, Li J, Liu C, Huang Q, Qu K
Molecular medicine (Cambridge, Mass.) 2025 May 27;31(1):209
Molecular medicine (Cambridge, Mass.) 2025 May 27;31(1):209
ZLN005, a PGC-1α agonist, delays photoreceptor degeneration by enhancing mitochondrial biogenesis in a murine model of retinitis pigmentosa.
Hu C, Ren C, Wu Y, Lin R, Shen T, Li T, Yu D, Jiang L, Wan Z, Luo Y, Su T, Yu J, Qiu Y
Neuropharmacology 2025 May 15;269:110361
Neuropharmacology 2025 May 15;269:110361
Dual regulation of mitochondrial fusion by Parkin-PINK1 and OMA1.
Yamada T, Ikeda A, Murata D, Wang H, Zhang C, Khare P, Adachi Y, Ito F, Quirós PM, Blackshaw S, López-Otín C, Langer T, Chan DC, Le A, Dawson VL, Dawson TM, Iijima M, Sesaki H
Nature 2025 Mar;639(8055):776-783
Nature 2025 Mar;639(8055):776-783
Leucine 7 is a key residue for mutant huntingtin-induced mitochondrial pathology and neurotoxicity in Huntington's disease.
Zhang S, Wang S, Yang Z, Li Y, Li J, Chen X, Yao H, Zheng Z, Guo X
The Journal of biological chemistry 2025 Mar;301(3):108297
The Journal of biological chemistry 2025 Mar;301(3):108297
Melatonin refines ovarian mitochondrial dysfunction in PCOS by regulating the circadian rhythm gene Clock.
Chen W, Zhang H, Guo B, Tao Y, Zhang J, Wang J, Chen G, Cheng M, Hong Q, Cao Y, Xie F
Cellular and molecular life sciences : CMLS 2025 Mar 6;82(1):104
Cellular and molecular life sciences : CMLS 2025 Mar 6;82(1):104
Impact of POU3F4 mutation on cochlear development and auditory function.
Dang J, Bian P, Chen C, Chen C, Shan W, Cai L, Li Y, Tan H, Xu B, Guan M, Guo Y
Cell communication and signaling : CCS 2025 Mar 5;23(1):121
Cell communication and signaling : CCS 2025 Mar 5;23(1):121
Polystyrene microplastics induce hepatic lipid metabolism and energy disorder by upregulating the NR4A1-AMPK signaling pathway.
Chiu HW, Chu CW, Huang CC, Chia ZC, Wang YL, Lee YH
Environmental pollution (Barking, Essex : 1987) 2025 Mar 15;369:125850
Environmental pollution (Barking, Essex : 1987) 2025 Mar 15;369:125850
PNPLA6 regulates retinal homeostasis by choline through phospholipid turnover.
Ono T, Taketomi Y, Higashi T, Sato H, Mochizuki-Ono C, Nagasaki Y, Ueta T, Miyai T, Tokuoka SM, Oda Y, Nishito Y, Ono T, Taya C, Arata S, Watanabe S, Soga T, Hirabayashi T, Aihara M, Murakami M
Nature communications 2025 Mar 13;16(1):2221
Nature communications 2025 Mar 13;16(1):2221
OPA1 deficiency induces mitophagy through PINK1/Parkin pathway during bovine oocytes maturation.
Han T, Zhao Y, Jiao A, Sun Z, Zhang H, Zhao D, Wang H, Gao Q
Theriogenology 2025 Mar 1;234:51-63
Theriogenology 2025 Mar 1;234:51-63
Neurotoxicity of Realgar: Crosstalk Between UBXD8-DRP1-Regulated Mitochondrial Fission and PINK1-Parkin-Mediated Mitophagy.
Feng R, Liu J, Yao T, Yang Z, Jiang H
Molecular neurobiology 2025 Jun;62(6):7041-7053
Molecular neurobiology 2025 Jun;62(6):7041-7053
Lycium barbarum polysaccharide alleviate cadmium-induced mitochondrial dysfunction mediated pyroptosis in duck liver.
Song J, Luo X, Xiong L, Li S, Chen Y, Liu W, Yuan Y, Ma Y, Bian J, Liu Z, Zou H
International journal of biological macromolecules 2025 Jun;311(Pt 4):143989
International journal of biological macromolecules 2025 Jun;311(Pt 4):143989
The crucial function of IDO1 in pulmonary fibrosis: From the perspective of mitochondrial fusion in lung fibroblasts and targeted molecular inhibition.
Wang L, Ge S, Zhang Y, Feng D, Zhu T, Zhang L, Zhang C
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3125-3148
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3125-3148
Intratracheal Administration of Polystyrene Micro(nano)plastics with a Mixed Particle Size Promote Pulmonary Fibrosis in Rats by Activating TGF-β1 Signaling and Destabilizing Mitochondrial Dynamics and Mitophagy in a Dose- and Time-Dependent Manner.
Xia S, Yuan C, Long W, Wu Z, Li X, Wang N, Gao M, Li Z, Li P, Liu P, Qu X, Sun L
Toxics 2025 Jun 9;13(6)
Toxics 2025 Jun 9;13(6)
Fluoride induces spermatocyte apoptosis by IP3R1/MCU-mediated mitochondrial calcium overload through MAMs.
Guo X, Wang L, Xuan J, Chen T, Du Y, Qiao H, Zhang S, Sun Z, Wang J, Niu R
Journal of hazardous materials 2025 Jun 5;489:137514
Journal of hazardous materials 2025 Jun 5;489:137514
PINK1 affects mitochondrial oxidative phosphorylation by regulating MFN2 to alleviate diabetic kidney disease.
Pei X, Liu J, Wei Y, Zhu Y, Li Y, Wang Q, Zhuang L, Jin G
International immunopharmacology 2025 Jun 5;157:114786
International immunopharmacology 2025 Jun 5;157:114786
Ginsenoside Rh2 Exerts a Therapeutic Effect against Myocardial Infarction via Promoting Angiogenesis and Mitochondrial Bioenergetics.
Duan Z, Yuan B, Li H, Yang J, Xiao X, Wei K
Journal of agricultural and food chemistry 2025 Jun 18;73(24):15056-15066
Journal of agricultural and food chemistry 2025 Jun 18;73(24):15056-15066
Transient AMPK activation by nutrient stress of high fat diet preserves cardiac electrophysiological stability and protects against arrhythmias.
Rudokas MW, McKay M, Wu X, Granger J, Williams Y, Bögner M, Kang T, Seyfried A, Toksoy Z, Cacheux M, Young LH, Akar FG
bioRxiv : the preprint server for biology 2025 Jun 14;
bioRxiv : the preprint server for biology 2025 Jun 14;
Downregulation of Mfn2 Contributes to Chronic Postsurgical Pain via Inducing the Pyroptosis of GABAergic Neurons in the Spinal Cord.
Hu Y, He X, Zang H, Chen Y, Li L, Liu T, Wan L, Zhu C, Yao W
CNS neuroscience & therapeutics 2025 Jul;31(7):e70508
CNS neuroscience & therapeutics 2025 Jul;31(7):e70508
Extremely low-frequency electromagnetic field (ELF-EMF) enhances mitochondrial energy production in NARP cybrids.
Ito M, Huang Z, Nomura K, Teranishi M, Zhao F, Mino H, Yoneda M, Tanaka M, Ohno K
Scientific reports 2025 Jul 8;15(1):24369
Scientific reports 2025 Jul 8;15(1):24369
Tang Bi formula alleviates diabetic sciatic neuropathy via AMPK/PGC-1α/MFN2 pathway activation.
Yang C, Yu H, Zhou L, Su H, Li X, Qi W, Lian F
Scientific reports 2025 Jul 11;15(1):25069
Scientific reports 2025 Jul 11;15(1):25069
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis.
Qiu C, Cheng L, Di D, Xiang Z, Wang C, Li J, Xiong Y, Li M, Liu J, Zhou J, Liu T, Wang X, Luo D, Wang X, Li S, Wang H, Wang X, Zhao Y, Liu X, Wang L
Genes & diseases 2025 Jan;12(1):101251
Genes & diseases 2025 Jan;12(1):101251
Klebsiella pneumoniae causes mammary gland damage via FNIP1-mediated mitochondrial dysfunction.
Dong P, Yuan C, Wang Z, Mao P, Liu K, Li J, Dong J, Cui L, Guo L, Meng X, Zhu G, Liu H, Wang R, Zhang L, Wang H
Journal of animal science 2025 Jan 4;103
Journal of animal science 2025 Jan 4;103
Stress-induced mitochondrial fragmentation in endothelial cells disrupts blood-retinal barrier integrity causing neurodegeneration.
Cueva-Vargas JL, Belforte N, Vidal-Paredes IA, Dotigny F, Vande Velde C, Quintero H, Di Polo A
bioRxiv : the preprint server for biology 2025 Jan 31;
bioRxiv : the preprint server for biology 2025 Jan 31;
Study on the role of Dihuang Yinzi in regulating the AMPK/SIRT1/PGC-1α pathway to promote mitochondrial biogenesis and improve Alzheimer's disease.
Zhu C, Zhang Z, Zhu Y, Du Y, Han C, Zhao Q, Li Q, Hou J, Zhang J, He W, Qin Y
Journal of ethnopharmacology 2025 Jan 30;337(Pt 2):118859
Journal of ethnopharmacology 2025 Jan 30;337(Pt 2):118859
Isovitexin targets SIRT3 to prevent steroid-induced osteonecrosis of the femoral head by modulating mitophagy-mediated ferroptosis.
Fan Y, Chen Z, Wang H, Jiang M, Lu H, Wei Y, Hu Y, Mo L, Liu Y, Zhou C, He W, Chen Z
Bone research 2025 Jan 26;13(1):18
Bone research 2025 Jan 26;13(1):18
Correcting mitochondrial loss mitigates NOTCH1-related aortopathy in mice.
Tang Y, Zhang J, Fang Y, Zhu K, Zhu J, Huang C, Xie Z, Zhang S, Ma W, Yan G, Liu S, Liu X, Han W, Xin Y, Yang C, Abudupataer M, Zhou P, He C, Lai H, Wang C, Liu Y, Lan F, Ye D, Yu FX, Xu Y, Zhang W
Nature cardiovascular research 2025 Feb;4(2):235-247
Nature cardiovascular research 2025 Feb;4(2):235-247
Ginsenoside Rb3 Promotes Opa1-Mediated Regenerative Neurogenesis via Activating the Ido1 Pathway in Ischemic Stroke.
Wang L, Qin N, Gao S, Zhu T
Phytotherapy research : PTR 2025 Feb;39(2):564-580
Phytotherapy research : PTR 2025 Feb;39(2):564-580
The Mitochondria-Targeted Micelle Inhibits Alzheimer's Disease Progression by Alleviating Neuronal Mitochondrial Dysfunction and Neuroinflammation.
Qian W, Liu D, Liu J, Liu M, Ji Q, Zhang B, Yang Z, Cheng Y, Zhou S
Small (Weinheim an der Bergstrasse, Germany) 2025 Feb;21(6):e2408581
Small (Weinheim an der Bergstrasse, Germany) 2025 Feb;21(6):e2408581
Chronic alcohol consumption exacerbates ischemia-associated skeletal muscle mitochondrial dysfunction in a murine model of peripheral artery disease.
Fletcher E, Miserlis D, Papoutsi E, Steiner JL, Gordon B, Haynatzki G, Pacher P, Koutakis P
Biochimica et biophysica acta. Molecular basis of disease 2025 Feb;1871(2):167584
Biochimica et biophysica acta. Molecular basis of disease 2025 Feb;1871(2):167584
SREBP1c-Mediated Transcriptional Repression of YME1L1 Contributes to Acute Kidney Injury by Inducing Mitochondrial Dysfunction in Tubular Epithelial Cells.
Xin W, Zhou J, Peng Y, Gong S, Liao W, Wang Y, Huang X, Mao Y, Yao M, Qin S, Xiong J, Li Y, Lan Q, Huang Y, Zhao J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(6):e2412233
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(6):e2412233
Salidroside protects against myocardial infarction via activating MIF-mediated mitochondrial quality control.
You B, Zhang J, Yang C, Dun Y, Qi D, Long Y, Cheng J, Lin Y, Zhou N, Zeng T, Dong J, Liu S
Chinese medicine 2025 Feb 28;20(1):27
Chinese medicine 2025 Feb 28;20(1):27
Urolithin A provides cardioprotection and mitochondrial quality enhancement preclinically and improves human cardiovascular health biomarkers.
Liu S, Faitg J, Tissot C, Konstantopoulos D, Laws R, Bourdier G, Andreux PA, Davey T, Gallart-Ayala H, Ivanisevic J, Singh A, Rinsch C, Marcinek DJ, D'Amico D
iScience 2025 Feb 21;28(2):111814
iScience 2025 Feb 21;28(2):111814
l-Glutamic Acid Alleviates Mastitis in Dairy Cows by Targeting the Sirt5/Nrf2/Prdx1 Signaling Axis and Mitochondrial Function.
Liu S, Jin Y, Zhou W, Liu J, Tu L, Zhang Y, Zhang M, Liu X, Cao Y, Guo W, Fu S
Journal of agricultural and food chemistry 2025 Feb 12;73(6):3483-3493
Journal of agricultural and food chemistry 2025 Feb 12;73(6):3483-3493
PANAXADIOL SAPONIN ALLEVIATES LPS-INDUCED CARDIOMYOPATHY SIMILAR TO DEXAMETHASONE VIA IMPROVING MITOCHONDRIAL QUALITY CONTROL.
Yang Z, Gao Y, Li D, Zhao L, Du Y
Shock (Augusta, Ga.) 2025 Feb 1;63(2):282-291
Shock (Augusta, Ga.) 2025 Feb 1;63(2):282-291
Up-regulation of cell apoptosis, autophagy and mitochondrial dynamics in ovarian granulosa cells of Daurian ground squirrels during the pre-hibernation period.
Wang X, Li H, Dong Z, Lu W, Chen J, Zhang H, Yuan Z, Liu Y, Weng Q, Han Y
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2025 Dec;310:111927
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2025 Dec;310:111927
ACTG1 mediates cisplatin resistance in NSCLC through induction of mitochondrial fragmentation.
Xie M, Yang Z, Zhou J, Chen X, Pu L, Xiong G, Chen M, Zhang H, Zhao Y, Yang Y
Apoptosis : an international journal on programmed cell death 2025 Dec;30(11-12):3069-3086
Apoptosis : an international journal on programmed cell death 2025 Dec;30(11-12):3069-3086
Hispolon reduces mitochondrial dysfunction and improves fibrosis of diabetes nephropathy by activating AMPK signal and inhibiting mPTP opening.
Wang Y, Danis A, Wang X, Ren J, Ma T, Wang R
Cellular signalling 2025 Dec;136:112130
Cellular signalling 2025 Dec;136:112130
KDM6B induces demethylation of H3K27me3 in MFN1 to modulate aberrant mitophagy in sepsis-induced acute lung injury.
Deng H, Zhu S, Song X, Guo Y, Ding X
Scientific reports 2025 Dec 8;15(1):43339
Scientific reports 2025 Dec 8;15(1):43339
Multi-Omics Analysis Reveals Distinct Lipid Remodelling and Mitochondrial Stress in SH-SY5Y Cells Modelling Parkinson's Disease.
Wang S, Ni Z, Wang G, Zhang J, Tan Y, Hong E, Wang Y, Chen H, Hou H, Hu Q
Metabolites 2025 Dec 4;15(12)
Metabolites 2025 Dec 4;15(12)
NDUFAB1 promotes hepatocellular carcinoma progression by disrupting mitochondrial homeostasis and mitophagy pathway.
Yao Z, Tan X, Cui H, Liang H, Zhong A, Man Y, Yi T, Zhang Z, Guo X, Tan S, Zhu X
International immunopharmacology 2025 Dec 10;167:115664
International immunopharmacology 2025 Dec 10;167:115664
FUNDC1-dependent mitochondrial-ER membranes mediate mitochondrial dysfunction and melanocyte damage under oxidative stress.
Ma J, Yuan M, Guo S, Gao T, Li C, Liu L
Free radical biology & medicine 2025 Dec 1;240:108-123
Free radical biology & medicine 2025 Dec 1;240:108-123
Leber's hereditary optic neuropathy-associated ND1 3733G>C mutation ameliorates the mitochondrial quality control and cellular homeostasis.
Yasheng M, Ji Y, He Y, Yi Q, Zhang H, Shan W, Wang K, Zhang J, Li Y, Meng F, Zhang M, Mo JQ, Wei S, Guan MX
The Journal of biological chemistry 2025 Aug;301(8):110464
The Journal of biological chemistry 2025 Aug;301(8):110464
Mn(2)O(3) NPs-induced liver injury is potentially associated with gut microbiota dysbiosis in broiler chicken.
Li Y, Yi J, Liu K, Liu X, Yangzom C, Pan J, Iqbal M, Hu L, Tang Z, Li Y, Zhang H
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Aug;202:115487
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Aug;202:115487
Decoding the role of nucleic acid binding protein 2 in lipid dysregulation and hepatocellular carcinoma progression through LKB1-mediated mitochondrial dysfunction.
Dai C, Tong Y, Bai N, Xu N, Zhao X, Zhou L, Tang Z, Liu M, Xu B, Liu X, Chen Y, Lin Z, Li J, Bian S, Zheng W
Cellular signalling 2025 Aug;132:111820
Cellular signalling 2025 Aug;132:111820
Melatonin mitigates arsenic and fluoride-induced cardiotoxicity in chickens by maintaining mitochondrial homeostasis.
Yuan X, Wen B, Hu X, Yang M, Han L, Zhao S, Zhang J, Ma Y
Poultry science 2025 Aug;104(8):105325
Poultry science 2025 Aug;104(8):105325
Targeting Wnt/beta-catenin signaling to attenuate short-chain chlorinated paraffins-triggered hepatocyte mitochondrial fission and subsequent pyroptosis.
Xiao J, Huang D, Wang F, Gan L, Zhang W, Zhang F, Tang J, Shen Z, Jiang M, Egbobe JO, Shao J, Wang X, Zhang Y, Ju L, Zhao X
International immunopharmacology 2025 Aug 28;161:115102
International immunopharmacology 2025 Aug 28;161:115102
NR3C1/GLMN-Mediated FKBP12.6 Ubiquitination Disrupts Calcium Homeostasis and Impairs Mitochondrial Quality Control in Stress-Induced Myocardial Damage.
Cong J, Liu L, Shi R, He M, An Y, Feng X, Yin X, Li Y, Cong B, Shi W
International journal of molecular sciences 2025 Aug 25;26(17)
International journal of molecular sciences 2025 Aug 25;26(17)
Radiocleavable rare-earth nanoactivators targeting over-expressed folate receptors induce mitochondrial dysfunction and remodel immune suppressive microenvironment in pancreatic cancer.
Gupta T, Wu SR, Chang LC, Lin FC, Shan YS, Yeh CS, Su WP
Journal of nanobiotechnology 2025 Aug 12;23(1):562
Journal of nanobiotechnology 2025 Aug 12;23(1):562
PGAM5 aggravated doxorubicin-induced cardiotoxicity by disturbing mitochondrial dynamics and exacerbating cardiomyocytes apoptosis.
He W, Wang J, He W, Zeng L, Zhao R, Qiu K, Tong G, Sun Z, He P
Free radical biology & medicine 2025 Aug 1;235:95-108
Free radical biology & medicine 2025 Aug 1;235:95-108
O-GlcNAcylation of hexokinase 2 modulates mitochondrial dynamics and enhances the progression of lung cancer.
Panpan SI, Wei GE, Kaiming WU, Zhang R
Molecular and cellular biochemistry 2025 Apr;480(4):2633-2643
Molecular and cellular biochemistry 2025 Apr;480(4):2633-2643
Dietary salt promotes cognitive impairment through repression of SIRT3/PINK1-mediated mitophagy and fission.
Fan H, Yuan M, Wang S, Yang X, Shu L, Pu Y, Zou Q, Zhang X, Wang C, Cai Z
Molecular and cellular biochemistry 2025 Apr;480(4):2345-2360
Molecular and cellular biochemistry 2025 Apr;480(4):2345-2360
Molybdenum nanodots act as antioxidants for photothermal therapy osteoarthritis.
Shi G, Lan S, Zhang Q, Wang J, Shu F, Hao Z, Chen T, Zhu M, Chen R, Chen J, Wu Z, Wu B, Zou Z, Li J
Biomaterials 2025 Apr;315:122909
Biomaterials 2025 Apr;315:122909
sLithospermic acid etched ZIF-8 nanoparticles delays osteoarthritis progression by inhibiting inflammatory signaling pathways and rescuing mitochondrial damage.
Zhang Y, Lou Q, Lian H, Yang R, Cui R, Wang L, Ma B, Hou L, Jin L, Teng W
Materials today. Bio 2025 Apr;31:101589
Materials today. Bio 2025 Apr;31:101589
Schisandrin B Improves Mitochondrial Function and Inhibits HT22 Cell Apoptosis by Regulating Sirt3 Protein.
Hu F, Tong S, Xu H
The Journal of membrane biology 2025 Apr;258(2):123-133
The Journal of membrane biology 2025 Apr;258(2):123-133
Evolocumab attenuates myocardial ischemia/reperfusion injury by blocking PCSK9/LIAS-mediated cuproptosis of cardiomyocytes.
Li ZZ, Guo L, An YL, Yu WJ, Shi DY, Lin QY, Zhang B
Basic research in cardiology 2025 Apr;120(2):301-320
Basic research in cardiology 2025 Apr;120(2):301-320
Butyrate Regulates Intestinal DNA Virome and Lipopolysaccharide Levels to Prevent High-Fat Diet-Related Liver Damage in Rats.
Zhang Z, Zhu T, Li Y, Yu B, Tao H, Zhao H, Cui B
Journal of agricultural and food chemistry 2025 Apr 9;73(14):8277-8289
Journal of agricultural and food chemistry 2025 Apr 9;73(14):8277-8289
Pharmacological targeting of the mitochondrial phosphatase PTPMT1 sensitizes hepatocellular carcinoma to ferroptosis.
Li M, Wang Y, Li X, Xu J, Yan L, Tang S, Liu C, Shi M, Liu R, Zhao Y, Zhang Y, Yang L, Zhang Y, Wang G, Li Z, Guo Y, Feng Y, Liu P
Cell death & disease 2025 Apr 6;16(1):257
Cell death & disease 2025 Apr 6;16(1):257
Loss of lipid droplet-mitochondria contacts confers protection against ethanol-induced cardiotoxicity.
He W, He W, Zeng L, Zhao R, Qiu K, He P, Sun Z, Tan N
Experimental cell research 2025 Apr 15;447(2):114517
Experimental cell research 2025 Apr 15;447(2):114517
ARMC1 partitions between distinct complexes and assembles MIRO with MTFR to control mitochondrial distribution.
McKenna MJ, Kraus F, Coelho JPL, Vasandani M, Zhang J, Adams BM, Paulo JA, Harper JW, Shao S
Science advances 2025 Apr 11;11(15):eadu5091
Science advances 2025 Apr 11;11(15):eadu5091
Asparagine transporter supports macrophage inflammation via histone phosphorylation.
Wang C, Ye Y, Zhao M, Chen Q, Liu B, Ren W
Science advances 2025 Apr 11;11(15):eads3506
Science advances 2025 Apr 11;11(15):eads3506
Blocking SLC7A11 attenuates the proliferation of esophageal squamous cell carcinoma cells.
Li WT, Jin X, Song SJ, Wang C, Fu C, Jiang W, Bai J, Shi ZZ
Animal cells and systems 2024;28(1):237-250
Animal cells and systems 2024;28(1):237-250
Mitochondrial Dysfunction by FADDosome Promotes Gastric Mucosal Injury in Portal Hypertensive Gastropathy.
Xiao Y, Zhang Y, Xie K, Huang X, Liu X, Luo J, Tan S
International journal of biological sciences 2024;20(7):2658-2685
International journal of biological sciences 2024;20(7):2658-2685
PTPLAD1 Regulates PHB-Raf Interaction to Orchestrate Epithelial-Mesenchymal and Mitofusion-Fission Transitions in Colorectal Cancer.
Huang ZJ, Li YJ, Yang J, Huang L, Zhao Q, Lu YF, Hu Y, Zhang WX, Liang JZ, Pan J, Pan YL, He QY, Wang Y
International journal of biological sciences 2024;20(6):2202-2218
International journal of biological sciences 2024;20(6):2202-2218
Dl-3-n-butylphthalide attenuates cerebral ischemia/reperfusion injury in mice through AMPK-mediated mitochondrial fusion.
Zhu T, Dong S, Qin N, Liu R, Shi L, Wan Q
Frontiers in pharmacology 2024;15:1357953
Frontiers in pharmacology 2024;15:1357953
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux.
He W, Sun Z, Tong G, Zeng L, He W, Chen X, Zhen C, Chen P, Tan N, He P
Theranostics 2024;14(9):3719-3738
Theranostics 2024;14(9):3719-3738
Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation.
Zhou J, Zhang L, Peng J, Zhang X, Zhang F, Wu Y, Huang A, Du F, Liao Y, He Y, Xie Y, Gu L, Kuang C, Ou W, Xie M, Tu T, Pang J, Zhang D, Guo K, Feng Y, Yin S, Cao Y, Li T, Jiang Y
Cell metabolism 2024 Sep 3;36(9):2054-2068.e14
Cell metabolism 2024 Sep 3;36(9):2054-2068.e14
Prophylactic Effects of Betaine on Depression and Anxiety Behaviors in Mice with Dextran Sulfate Sodium-Induced Colitis.
Liu W, Zhong X, Yi Y, Xie L, Zhou W, Cao W, Chen L
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21041-21051
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21041-21051
mCAUSE: Prioritizing mitochondrial targets that alleviate pancreatic cancer cell phenotypes.
Murata D, Ito F, Tang G, Iwata W, Yeung N, West JJ, Ewald AJ, Wang X, Iijima M, Sesaki H
iScience 2024 Sep 20;27(9):110880
iScience 2024 Sep 20;27(9):110880
MMP9 drives ferroptosis by regulating GPX4 and iron signaling.
Gawargi FI, Mishra PK
iScience 2024 Sep 20;27(9):110622
iScience 2024 Sep 20;27(9):110622
Helicobacter pylori CagA mediated mitophagy to attenuate the NLRP3 inflammasome activation and enhance the survival of infected cells.
Chen D, Wu L, Liu X, Wang Q, Gui S, Bao L, Wang Z, He X, Zhao Y, Zhou J, Xie Y
Scientific reports 2024 Sep 17;14(1):21648
Scientific reports 2024 Sep 17;14(1):21648
Dysregulation of mitochondrial dynamics and mitophagy are involved in high-fat diet-induced steroidogenesis inhibition.
Lv ZM, Liu C, Wang P, Chen YH
Journal of lipid research 2024 Oct;65(10):100639
Journal of lipid research 2024 Oct;65(10):100639
Neuronal HIPK2-HDAC3 axis regulates mitochondrial fragmentation to participate in stroke injury and post-stroke anxiety like behavior.
Yang M, Zhu H, Peng L, Yin T, Sun S, Du Y, Li J, Liu J, Wang S
Experimental neurology 2024 Oct;380:114906
Experimental neurology 2024 Oct;380:114906
Resveratrol protects against a high-fat diet-induced neuroinflammation by suppressing mitochondrial fission via targeting SIRT1/PGC-1α.
Su X, Li Q, Yang M, Zhang W, Liu X, Ba Y, Deng Q, Zhang Y, Han L, Huang H
Experimental neurology 2024 Oct;380:114899
Experimental neurology 2024 Oct;380:114899
SIRT1 regulates mitochondrial fission to alleviate high altitude hypoxia inducedcardiac dysfunction in rats via the PGC-1α-DRP1/FIS1/MFF pathway.
Xu H, Song X, Zhang X, Wang G, Cheng X, Zhang L, Wang Z, Li R, Ai C, Wang X, Pu L, Chen Z, Liu W
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1663-1678
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1663-1678
Mfn2(R364W), Mfn2(G176S), and Mfn2(H165R) mutations drive Charcot-Marie-Tooth type 2A disease by inducing apoptosis and mitochondrial oxidative phosphorylation damage.
Zhang Y, Ma L, Wang Z, Gao C, Yang L, Li M, Tang X, Yuan H, Pang D, Ouyang H
International journal of biological macromolecules 2024 Oct;278(Pt 1):134673
International journal of biological macromolecules 2024 Oct;278(Pt 1):134673
Qifu-yin activates the Keap1/Nrf2/ARE signaling and ameliorates synaptic injury and oxidative stress in APP/PS1 mice.
Wang S, Huang J, Chen Y, Liang Y, Chen L, Ye D, Yang H, Hui Z, Wang X, Zhang Z, Zhu X
Journal of ethnopharmacology 2024 Oct 28;333:118497
Journal of ethnopharmacology 2024 Oct 28;333:118497
Apoptosis, Mitochondrial Autophagy, Fission, and Fusion Maintain Mitochondrial Homeostasis in Mouse Liver Under Tail Suspension Conditions.
Li LF, Yu J, Li R, Li SS, Huang JY, Wang MD, Jiang LN, Xu JH, Wang Z
International journal of molecular sciences 2024 Oct 18;25(20)
International journal of molecular sciences 2024 Oct 18;25(20)
Dapagliflozin alleviates right heart failure by promoting collagen degradation by reducing ROS levels.
Liu DD, Liu XL, Zheng TF, Li X, Zhao YC, Pan JC, Yuan C, Wang QQ, Zhang M
European journal of pharmacology 2024 Oct 15;981:176875
European journal of pharmacology 2024 Oct 15;981:176875
Characterization of fission and fusion mitochondrial dynamics in HD fibroblasts according to patient's severity status.
Gharaba S, Sprecher U, Baransi A, Muchtar N, Weil M
Neurobiology of disease 2024 Oct 15;201:106667
Neurobiology of disease 2024 Oct 15;201:106667
Yiqihuoxue decoction (GSC) inhibits mitochondrial fission through the AMPK pathway to ameliorate EPCs senescence and optimize vascular aging transplantation regimens.
Liu Y, Niu Z, Wang X, Xiu C, Hu Y, Wang J, Lei Y, Yang J
Chinese medicine 2024 Oct 14;19(1):143
Chinese medicine 2024 Oct 14;19(1):143
Contribution of impaired autophagy, mitochondrial dysfunction and abnormal lipolysis to epididymal aging in mice.
Liu C, Wu C, Zhang S, Lv Z
Experimental gerontology 2024 Oct 1;195:112528
Experimental gerontology 2024 Oct 1;195:112528
Renal denervation ameliorates atrial remodeling in type 2 diabetic rats by regulating mitochondrial dynamics.
Huo JY, Hou C, Li XL, Yang L, Jiang WY
Journal of physiology and biochemistry 2024 Nov;80(4):935-948
Journal of physiology and biochemistry 2024 Nov;80(4):935-948
Cellular ATP demand creates metabolically distinct subpopulations of mitochondria.
Ryu KW, Fung TS, Baker DC, Saoi M, Park J, Febres-Aldana CA, Aly RG, Cui R, Sharma A, Fu Y, Jones OL, Cai X, Pasolli HA, Cross JR, Rudin CM, Thompson CB
Nature 2024 Nov;635(8039):746-754
Nature 2024 Nov;635(8039):746-754
E3 ubiquitin ligase TRIM31 alleviates dopaminergic neurodegeneration by promoting proteasomal degradation of VDAC1 in Parkinson's Disease model.
Zhao Z, Song X, Wang Y, Yu L, Huang G, Li Y, Zong R, Liu T, Ji Q, Zheng Y, Liu B, Zhu Q, Chen L, Gao C, Liu H
Cell death and differentiation 2024 Nov;31(11):1410-1421
Cell death and differentiation 2024 Nov;31(11):1410-1421
Hydrogen Protects Mitochondrial Function by Increasing the Expression of PGC-1α and Ameliorating Myocardial Ischaemia-Reperfusion Injury.
Zuo Y, Wang J, Gong Z, Wang Y, Wang Q, Yang X, Liu F, Liu T
Journal of cellular and molecular medicine 2024 Nov;28(22):e70236
Journal of cellular and molecular medicine 2024 Nov;28(22):e70236
Mitochondrial elongation confers protection against doxorubicin-induced cardiotoxicity.
He W, He W, Chen X, Zeng L, Zeng L, Liu Y, He P, Sun Z
Biochemical pharmacology 2024 Nov;229:116495
Biochemical pharmacology 2024 Nov;229:116495
Psmb8 inhibits mitochondrial fission and alleviates myocardial ischaemia/reperfusion injury by targeting Drp1 degradation.
Su HX, Xu LL, Li PB, Bi HL, Jiang WX, Li HH
Cell death & disease 2024 Nov 8;15(11):803
Cell death & disease 2024 Nov 8;15(11):803
Targeting DUSP26 to drive cardiac mitochondrial dynamics via FAK-ERK signaling in diabetic cardiomyopathy.
Liu C, Xu X, Sun G, Song C, Jiang S, Sun P, Tian J
Free radical biology & medicine 2024 Nov 20;225:856-870
Free radical biology & medicine 2024 Nov 20;225:856-870
Acrolein exposure affects ovarian function by interfering with glycolysis and mitochondrial energy metabolism in mouse.
Chen YZ, Wang WK, Yang YF, Cheng SY, Li LF, Shen H, Qi ZM, Liu Y
Environmental pollution (Barking, Essex : 1987) 2024 Nov 15;361:124776
Environmental pollution (Barking, Essex : 1987) 2024 Nov 15;361:124776
TRPA1 protects against contrast-induced renal tubular injury by preserving mitochondrial dynamics via the AMPK/DRP1 pathway.
Wang X, Luo T, Yang Y, Yang L, Liu M, Zou Q, Wang D, Yang C, Xue Q, Liu S, Wan J, He G, Zeng A, Hou J, Ma S, Wang P
Free radical biology & medicine 2024 Nov 1;224:521-539
Free radical biology & medicine 2024 Nov 1;224:521-539
Deafness-associated tRNA(Phe) mutation impaired mitochondrial and cellular integrity.
Chen X, Meng F, Chen C, Li S, Chou Z, Xu B, Mo JQ, Guo Y, Guan MX
The Journal of biological chemistry 2024 May;300(5):107235
The Journal of biological chemistry 2024 May;300(5):107235
Metaplastic regeneration in the mouse stomach requires a reactive oxygen species pathway.
Miao ZF, Sun JX, Huang XZ, Bai S, Pang MJ, Li JY, Chen HY, Tong QY, Ye SY, Wang XY, Hu XH, Li JY, Zou JW, Xu W, Yang JH, Lu X, Mills JC, Wang ZN
Developmental cell 2024 May 6;59(9):1175-1191.e7
Developmental cell 2024 May 6;59(9):1175-1191.e7
Silent information regulator 2 deficiency exacerbates chronic cold exposure-induced colonic injury and p65 activation in mice.
Guo J, Zhang H, Hu H, Zhao T, Ji H, Ma L, Lu J, Yuan J, Xu B
Gene 2024 May 20;907:148276
Gene 2024 May 20;907:148276
Mitochondrial SIRT3 as a protective factor against cyclosporine A-induced nephrotoxicity.
Kim JE, Jo MJ, Bae SY, Ahn SY, Ko GJ, Kwon YJ
Scientific reports 2024 May 2;14(1):10143
Scientific reports 2024 May 2;14(1):10143
Puerarin Delays Mammary Gland Aging by Regulating Gut Microbiota and Inhibiting the p38MAPK Signaling Pathway.
Liu S, Hu H, Zhang M, Zhang Y, Geng R, Jin Y, Cao Y, Guo W, Liu J, Fu S
Journal of agricultural and food chemistry 2024 May 15;72(19):10879-10896
Journal of agricultural and food chemistry 2024 May 15;72(19):10879-10896
Environmental cadmium inhibits testicular testosterone synthesis via Parkin-dependent MFN1 degradation.
Wang TT, Zhu HL, Ouyang KW, Wang H, Luo YX, Zheng XM, Ling Q, Wang KW, Zhang J, Chang W, Lu Q, Zhang YF, Yuan Z, Li H, Xiong YW, Wei T, Wang H
Journal of hazardous materials 2024 May 15;470:134142
Journal of hazardous materials 2024 May 15;470:134142
Rapamycin alleviates mitochondrial dysfunction in anti-NMDAR encephalitis mice.
Kong L, Yang X, Sun A, Yang X, Zhao X, Wang S
International immunopharmacology 2024 May 10;132:111910
International immunopharmacology 2024 May 10;132:111910
IGF2BP3-stabilized CAMK1 regulates the mitochondrial dynamics of renal tubule to alleviate diabetic nephropathy.
Yuan D, Li H, Dai W, Zhou X, Zhou W, He L
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167022
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167022
Ubiquitinome Analysis Uncovers Alterations in Synaptic Proteins and Glucose Metabolism Enzymes in the Hippocampi of Adolescent Mice Following Cold Exposure.
Li XY, Yin X, Lu JJ, Li QR, Xing WQ, Han Q, Ji H, Li SZ, Yang HM, Guo JR, Wang ZQ, Xu B
Cells 2024 Mar 25;13(7)
Cells 2024 Mar 25;13(7)
Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.
Shi L, Yang J, Tao Z, Zheng L, Bui TF, Alonso RL, Yue F, Cheng Z
Clinical science (London, England : 1979) 2024 Mar 20;138(6):371-385
Clinical science (London, England : 1979) 2024 Mar 20;138(6):371-385
Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia-inducible factor-1α in normoxia.
Welch N, Mishra S, Bellar A, Kannan P, Gopan A, Goudarzi M, King J, Luknis M, Musich R, Agrawal V, Bena J, Koch CJ, Li L, Willard B, Shah YM, Dasarathy S
The Journal of physiology 2024 Jun;602(12):2763-2806
The Journal of physiology 2024 Jun;602(12):2763-2806
Mechanistic of AMPK/ACC2 regulating myoblast differentiation by fatty acid oxidation of goat.
Kang Z, Zhang Z, Li J, Deng K, Wang F, Fan Y
International journal of biological macromolecules 2024 Jun;270(Pt 2):132243
International journal of biological macromolecules 2024 Jun;270(Pt 2):132243
Imbalanced mitochondrial dynamics contributes to the pathogenesis of X-linked adrenoleukodystrophy.
Launay N, Lopez-Erauskin J, Bianchi P, Guha S, Parameswaran J, Coppa A, Torreni L, Schlüter A, Fourcade S, Paredes-Fuentes AJ, Artuch R, Casasnovas C, Ruiz M, Pujol A
Brain : a journal of neurology 2024 Jun 3;147(6):2069-2084
Brain : a journal of neurology 2024 Jun 3;147(6):2069-2084
Targeting DRP1 with Mdivi-1 to correct mitochondrial abnormalities in ADOA+ syndrome.
Lin Y, Wang D, Li B, Wang J, Xu L, Sun X, Ji K, Yan C, Liu F, Zhao Y
JCI insight 2024 Jun 25;9(15)
JCI insight 2024 Jun 25;9(15)
CIAO1 loss of function causes a neuromuscular disorder with compromise of nucleocytoplasmic Fe-S enzymes.
Maio N, Orbach R, Zaharieva IT, Töpf A, Donkervoort S, Munot P, Mueller J, Willis T, Verma S, Peric S, Krishnakumar D, Sudhakar S, Foley AR, Silverstein S, Douglas G, Pais L, DiTroia S, Grunseich C, Hu Y, Sewry C, Sarkozy A, Straub V, Muntoni F, Rouault TA, Bönnemann CG
The Journal of clinical investigation 2024 Jun 17;134(12)
The Journal of clinical investigation 2024 Jun 17;134(12)
Decreasing mitochondrial fission ameliorates HIF-1α-dependent pathological retinal angiogenesis.
Huang SQ, Cao KX, Wang CL, Chen PL, Chen YX, Zhang YT, Yu SH, Bai ZX, Guo S, Liao MX, Li QW, Zhang GQ, He J, Xu YM
Acta pharmacologica Sinica 2024 Jul;45(7):1438-1450
Acta pharmacologica Sinica 2024 Jul;45(7):1438-1450
Mitochondria-Targeted Natural Antioxidant Nanosystem for Diabetic Vascular Calcification Therapy.
Li J, Lan T, Guo Q, Zhang C, Lu X, Hu X, Shen X, Zhang Y
Biomacromolecules 2024 Jul 8;25(7):4329-4343
Biomacromolecules 2024 Jul 8;25(7):4329-4343
Acid Neutralization by Composite Lysine Nanoparticles for Spinal Cord Injury Recovery through Mitigating Mitochondrial Dysfunction.
Wang Q, Ge L, Guo J, Zhang H, Chen T, Lian F, Li L, Xu Y, Xu J, Chen N, Zhang Y, Ruan Z, Xiao J, Zhang H, Yang L
ACS biomaterials science & engineering 2024 Jul 8;10(7):4480-4495
ACS biomaterials science & engineering 2024 Jul 8;10(7):4480-4495
Paeoniflorin Promotes Ovarian Development in Mice by Activating Mitophagy and Preventing Oxidative Stress.
Xi H, Wang Z, Li M, Duan X, Li Y
International journal of molecular sciences 2024 Jul 30;25(15)
International journal of molecular sciences 2024 Jul 30;25(15)
Zearalenone modulates the function of goat endometrial cells via the mitochondrial quality control system.
Zhang G, Zeng C, Sun X, Zhang Q, Wang Y, Xia R, Mai Q, Xue G, Huang H, Wang F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23701
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23701
Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury.
Liu YT, Zhang H, Duan SB, Wang JW, Chen H, Zhan M, Zhang W, Li AM, Liu Y, Yang Y, Yang S
Antioxidants & redox signaling 2024 Jan;40(1-3):16-39
Antioxidants & redox signaling 2024 Jan;40(1-3):16-39
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
Yang C, Luo P, Yang YT, Fu XL, Li BX, Shen X, Xu DN, Huang YM, Tian YB, Liu WJ
Poultry science 2024 Jan;103(1):103247
Poultry science 2024 Jan;103(1):103247
High-fat diet-induced L-saccharopine accumulation inhibits estradiol synthesis and damages oocyte quality by disturbing mitochondrial homeostasis.
Wen J, Feng Y, Xue L, Yuan S, Chen Q, Luo A, Wang S, Zhang J
Gut microbes 2024 Jan-Dec;16(1):2412381
Gut microbes 2024 Jan-Dec;16(1):2412381
MCT1-governed pyruvate metabolism is essential for antibody class-switch recombination through H3K27 acetylation.
Chi W, Kang N, Sheng L, Liu S, Tao L, Cao X, Liu Y, Zhu C, Zhang Y, Wu B, Chen R, Cheng L, Wang J, Sun X, Liu X, Deng H, Yang J, Li Z, Liu W, Chen L
Nature communications 2024 Jan 2;15(1):163
Nature communications 2024 Jan 2;15(1):163
Activation of Ca(2+) phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies.
Marchesan E, Nardin A, Mauri S, Bernardo G, Chander V, Di Paola S, Chinellato M, von Stockum S, Chakraborty J, Herkenne S, Basso V, Schrepfer E, Marin O, Cendron L, Medina DL, Scorrano L, Ziviani E
Cell death and differentiation 2024 Feb;31(2):217-238
Cell death and differentiation 2024 Feb;31(2):217-238
NSD2 modulates Drp1-mediated mitochondrial fission in chronic renal allograft interstitial fibrosis by methylating STAT1.
Zhang J, Xie W, Ni B, Li Z, Feng D, Zhang Y, Han Q, Zhou H, Gu M, Tan R
Pharmacological research 2024 Feb;200:107051
Pharmacological research 2024 Feb;200:107051
Chronic Sleep Deprivation Impairs Visual Functions via Oxidative Damage in Mice.
Tang L, Zhang H, Liao Y, Zhou S, Yang Y, Zhang M, Guo Y, Xie T, Chen S, Ouyang W, Lin X, Wang S, Huang C, Zhang M, Zhuang J, Zhao J, Zhang R, Zhang C, Jin Z, Hu J, Liu Z
The American journal of pathology 2024 Feb;194(2):307-320
The American journal of pathology 2024 Feb;194(2):307-320
ZNF746 plays cardinal roles on colorectal cancer (CRC) cell invasion and migration and regulates mitochondrial dynamics and morphological changes of CRC cells-Role of combined melatonin and 5-FU regimen.
Huang CR, Chu YT, Chang CL, Yip HK, Chen HH
Journal of cellular biochemistry 2024 Feb;125(2):e30507
Journal of cellular biochemistry 2024 Feb;125(2):e30507
Effects of metformin on glucose metabolism and mitochondrial function in patients with obstructive sleep apnea: A pilot randomized trial.
Zunica ERM, Heintz EC, Dantas WS, Hebert RC, Tanksley M, Beyl RA, Mader EC Jr, Kirwan JP, Axelrod CL, Singh P
Physiological reports 2024 Feb;12(3):e15948
Physiological reports 2024 Feb;12(3):e15948
Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis.
He Y, Zhu G, Li X, Zhou M, Guan MX
iScience 2024 Feb 16;27(2):108883
iScience 2024 Feb 16;27(2):108883
Serine synthesis sustains macrophage IL-1β production via NAD(+)-dependent protein acetylation.
Wang C, Chen Q, Chen S, Fan L, Gan Z, Zhao M, Shi L, Bin P, Yang G, Zhou X, Ren W
Molecular cell 2024 Feb 15;84(4):744-759.e6
Molecular cell 2024 Feb 15;84(4):744-759.e6
Mitochondrial dynamics disruption: Unraveling Dinotefuran's impact on cardiotoxicity.
Zhu J, Tao Q, Du G, Huang L, Li M, Wang M, Wang Q
Environmental pollution (Barking, Essex : 1987) 2024 Feb 15;343:123238
Environmental pollution (Barking, Essex : 1987) 2024 Feb 15;343:123238
Antrodia cinnamomea triterpenoids attenuate cardiac hypertrophy via the SNW1/RXR/ALDH2 axis.
Ma Y, Wang Y, Anwaier G, Tuerdi N, Wu Y, Huang Y, Qin B, Ma H, Zhang Q, Wu D, Zeng K, Qi R
Redox biology 2024 Dec;78:103437
Redox biology 2024 Dec;78:103437
Mesenchymal stem cell-loaded hydrogel to inhibit inflammatory reaction in surgical brain injury via mitochondria transfer.
Wang Y, Yang X, Liu M, Yan Y, Kong F, Wang J, Zhang Z, Chen Y, Chen L, Liang Z, Peng X, Liu F
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:231-240
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:231-240
Mitochondrial mechanotransduction through MIEF1 coordinates the nuclear response to forces.
Romani P, Benedetti G, Cusan M, Arboit M, Cirillo C, Wu X, Rouni G, Kostourou V, Aragona M, Giampietro C, Grumati P, Martello G, Dupont S
Nature cell biology 2024 Dec;26(12):2046-2060
Nature cell biology 2024 Dec;26(12):2046-2060
Hyperglycemia-depleted glutamine contributes to the pathogenesis of diabetic corneal endothelial dysfunction.
Yu M, Chen H, Chen C, Zhao C, Zhou Q, Xie L, Wang T
Experimental eye research 2024 Dec;249:110124
Experimental eye research 2024 Dec;249:110124
Oleanonic acid ameliorates mutant Aβ precursor protein-induced oxidative stress, autophagy deficits, ferroptosis, mitochondrial damage, and ER stress in vitro.
Tao L, Liu Z, Li X, Wang H, Wang Y, Zhou D, Zhang H
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167459
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167459
Cardiomyocyte STIM1 downregulation exacerbates post-Myocardial Infarction remodeling by dysregulating mitochondrial ultrastructure and metabolic signaling.
Cacheux M, Velasco J, Wu X, Strauss B, Akar FG
bioRxiv : the preprint server for biology 2024 Dec 9;
bioRxiv : the preprint server for biology 2024 Dec 9;
Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia.
Sun T, Yu H, Zhang D, Li D, Fu J
Respiratory research 2024 Dec 26;25(1):443
Respiratory research 2024 Dec 26;25(1):443
IDH1/MDH1 deacetylation promotes NETosis by regulating OPA1 and autophagy.
Wang Y, Guo J, Zhang D, Shi C, Zhang X, Gong Z
International immunopharmacology 2024 Dec 25;143(Pt 1):113270
International immunopharmacology 2024 Dec 25;143(Pt 1):113270
Myricetin Alleviates Silica-Mediated Lung Fibrosis via PPARγ-PGC-1α Loop and Suppressing Mitochondrial Senescence in Epithelial Cells.
Xie W, Deng L, Zhang X, Huang X, Ding J, Liu W, Tang SY
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27737-27749
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27737-27749
Disturbance of mitochondrial dynamics led to spermatogenesis disorder in mice exposed to polystyrene micro- and nanoplastics.
Zhao M, Xie J, Zhang J, Zhao B, Zhang Y, Xue J, Zhang R, Zhang R, Wang H, Li Y, Ge W, Zhou X
Environmental pollution (Barking, Essex : 1987) 2024 Dec 1;362:124935
Environmental pollution (Barking, Essex : 1987) 2024 Dec 1;362:124935
Presenilin2 D439A Mutation Induces Dysfunction of Mitochondrial Fusion/Fission Dynamics and Abnormal Regulation of GTPase Activity.
Gao C, Shang J, Sun Z, Xia M, Gao D, Sun R, Li W, Wang F, Zhang J
Molecular neurobiology 2024 Aug;61(8):5047-5070
Molecular neurobiology 2024 Aug;61(8):5047-5070
Aldehyde Dehydrogenase 2 Deficiency Aggravates Lung Fibrosis through Mitochondrial Dysfunction and Aging in Fibroblasts.
Wei Y, Gao S, Li C, Huang X, Xie B, Geng J, Dai H, Wang C
The American journal of pathology 2024 Aug;194(8):1458-1477
The American journal of pathology 2024 Aug;194(8):1458-1477
The effects of the atrial natriuretic peptide deficiency on renal cortical mitochondrial bioenergetics in the Dahl SS rat.
Cherezova A, Sudarikova A, Vasileva V, Iurchenko R, Nikiforova A, Spires DR, Zamaro AS, Jones AC, Schibalski RS, Dong Z, Palygin O, Stadler K, Ilatovskaya DV
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 31;38(16):e23891
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 31;38(16):e23891
Pathological characteristics of axons and alterations of proteomic and lipidomic profiles in midbrain dopaminergic neurodegeneration induced by WDR45-deficiency.
Wang P, Shao Y, Al-Nusaif M, Zhang J, Yang H, Yang Y, Kim K, Li S, Liu C, Cai H, Le W
Molecular neurodegeneration 2024 Aug 26;19(1):62
Molecular neurodegeneration 2024 Aug 26;19(1):62
Nrf2 expression, mitochondrial fission, and neuronal apoptosis in the prefrontal cortex of methamphetamine abusers and rats.
Nie QY, Yang GM, Zhang P, Dong WJ, Jing D, Hou ZP, Peng YX, Yu Y, Li LH, Hong SJ
Brain research 2024 Aug 15;1837:148973
Brain research 2024 Aug 15;1837:148973
Mfn2 induces NCLX-mediated calcium release from mitochondria.
Kolitsida P, Saha A, Caliri A, Assali E, Riera AM, Itskanov S, Magana CS, Stork B, Shirihai O, Sekler I, Koehler CM, van der Bliek AM
bioRxiv : the preprint server for biology 2024 Aug 13;
bioRxiv : the preprint server for biology 2024 Aug 13;
The mechanism of extracellular CypB promotes glioblastoma adaptation to glutamine deprivation microenvironment.
Yin H, Liu Y, Dong Q, Wang H, Yan Y, Wang X, Wan X, Yuan G, Pan Y
Cancer letters 2024 Aug 10;597:216862
Cancer letters 2024 Aug 10;597:216862
VDR regulates mitochondrial function as a protective mechanism against renal tubular cell injury in diabetic rats.
Chen H, Zhang H, Li AM, Liu YT, Liu Y, Zhang W, Yang C, Song N, Zhan M, Yang S
Redox biology 2024 Apr;70:103062
Redox biology 2024 Apr;70:103062
Disturbance of mitochondrial dynamics in myocardium of broilers with pulmonary hypertension syndrome.
Zhang W, Li M, Ye X, Jiang M, Wu X, Tang Z, Hu L, Zhang H, Li Y, Pan J
British poultry science 2024 Apr;65(2):154-164
British poultry science 2024 Apr;65(2):154-164
Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia-reperfusion injury.
Chen X, Yang T, Zhou Y, Mei Z, Zhang W
CNS neuroscience & therapeutics 2024 Apr;30(4):e14725
CNS neuroscience & therapeutics 2024 Apr;30(4):e14725
Schisandrin B Alleviates LPS Induced Mitochondrial Damage in C28I2 Cells.
Hu F, Hu W, Xu H
The Journal of membrane biology 2024 Apr;257(1-2):107-114
The Journal of membrane biology 2024 Apr;257(1-2):107-114
The NLRX1-SLC39A7 complex orchestrates mitochondrial dynamics and mitophagy to rejuvenate intervertebral disc by modulating mitochondrial Zn(2+) trafficking.
Song Y, Liang H, Li G, Ma L, Zhu D, Zhang W, Tong B, Li S, Gao Y, Wu X, Zhang Y, Feng X, Wang K, Yang C
Autophagy 2024 Apr;20(4):809-829
Autophagy 2024 Apr;20(4):809-829
Mitochondrial dysfunction induced by HIF-1α under hypoxia contributes to the development of gastric mucosal lesions.
Xiao Y, Liu X, Xie K, Luo J, Zhang Y, Huang X, Luo J, Tan S
Clinical and translational medicine 2024 Apr;14(4):e1653
Clinical and translational medicine 2024 Apr;14(4):e1653
Moderate replacement of fish oil with palmitic acid-stimulated mitochondrial fusion promotes β-oxidation by Mfn2 interacting with Cpt1α via its GTPase-domain.
Song YF, Wang LJ, Luo Z, Hogstrand C, Lai XH, Zheng FF
The Journal of nutritional biochemistry 2024 Apr;126:109559
The Journal of nutritional biochemistry 2024 Apr;126:109559
TMAO promotes vascular endothelial cell pyroptosis via the LPEAT-mitophagy pathway.
Chen Y, Yuan C, Qin W, Yu B, Wei D, Wu P
Biochemical and biophysical research communications 2024 Apr 9;703:149667
Biochemical and biophysical research communications 2024 Apr 9;703:149667
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Wang L, Wang B, Zhang X, Yang Z, Zhang X, Gong H, Song Y, Zhang K, Sun M
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Icaritin with autophagy/mitophagy inhibitors synergistically enhances anticancer efficacy and apoptotic effects through PINK1/Parkin-mediated mitophagy in hepatocellular carcinoma.
Luo P, An Y, He J, Xing X, Zhang Q, Liu X, Chen Y, Yuan H, Chen J, Wong YK, Huang J, Gong Z, Du Q, Xiao W, Wang J
Cancer letters 2024 Apr 10;587:216621
Cancer letters 2024 Apr 10;587:216621
LonP1 Links Mitochondria-ER Interaction to Regulate Heart Function.
Li Y, Huang D, Jia L, Shangguan F, Gong S, Lan L, Song Z, Xu J, Yan C, Chen T, Tan Y, Liu Y, Huang X, Suzuki CK, Yang Z, Yang G, Lu B
Research (Washington, D.C.) 2023;6:0175
Research (Washington, D.C.) 2023;6:0175
ShenQiWan ameliorates renal injury in type 2 diabetic mice by modulating mitochondrial fusion and endoplasmic reticulum stress.
Xiong W, Feng J, Liu Y, Liu J, Fu L, Wang Q, Li X, Li S
Frontiers in pharmacology 2023;14:1265551
Frontiers in pharmacology 2023;14:1265551
Exercise prevents fatal stress-induced myocardial injury in obese mice.
Dun Y, Hu Z, You B, Du Y, Zeng L, Zhao Y, Liu Y, Wu S, Cui N, Yang F, Liu S
Frontiers in endocrinology 2023;14:1223423
Frontiers in endocrinology 2023;14:1223423
Blockage of S100A8/A9 ameliorates septic nephropathy in mice.
Shi W, Wan TT, Li HH, Guo SB
Frontiers in pharmacology 2023;14:1172356
Frontiers in pharmacology 2023;14:1172356
Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.
Liu Y, Zhang H, Liu Y, Zhang S, Su P, Wang L, Li Y, Liang Y, Wang X, Zhao W, Chen B, Luo D, Zhang N, Yang Q
Autophagy 2023 Sep;19(9):2443-2463
Autophagy 2023 Sep;19(9):2443-2463
Arsenic induced autophagy-dependent apoptosis in hippocampal neurons via AMPK/mTOR signaling pathway.
Chen Y, Liu X, Zhang Q, Wang H, Zhang R, Ge Y, Liang H, Li W, Fan J, Liu H, Lv Z, Dou W, Wang Y, Li X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113954
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113954
Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy.
Wang Z, Wang XC, Chen YF, Wang CL, Chen L, Jiang MY, Liu XW, Zhang XX, Feng YZ, Xu JH
Experimental physiology 2023 Sep;108(9):1189-1202
Experimental physiology 2023 Sep;108(9):1189-1202
Mitochondrial miR-12294-5p regulated copper-induced mitochondrial oxidative stress and mitochondrial quality control imbalance by targeted inhibition of CISD1 in chicken livers.
Zhong G, Li Y, Li L, Huo Y, Zhang W, Li T, Ma F, Liao J, Li Y, Zhang H, Guo J, Pan J, Yu W, Hu L, Tang Z
Journal of hazardous materials 2023 Sep 15;458:131908
Journal of hazardous materials 2023 Sep 15;458:131908
Paternal cadmium exposure affects estradiol synthesis by impairing intracellular cholesterol homeostasis and mitochondrial function in offspring female mice.
Zhang Y, Zhou J, Zeng L, Xiong Y, Wang X, Xiang W, Su P
Ecotoxicology and environmental safety 2023 Sep 15;263:115280
Ecotoxicology and environmental safety 2023 Sep 15;263:115280
Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission.
Liang XL, Ouyang L, Yu NN, Sun ZH, Gui ZK, Niu YL, He QY, Zhang J, Wang Y
Journal of pharmaceutical analysis 2023 Oct;13(10):1168-1182
Journal of pharmaceutical analysis 2023 Oct;13(10):1168-1182
Polydatin improves vascular endothelial function by maintaining mitochondrial homeostasis under high glucose conditions.
Shah W, Zhao Q, Wang S, Zhang M, Ma H, Guan Y, Zhang Y, Liu Y, Zhu C, Wang S, Zhang X, Dong J, Ma H
Scientific reports 2023 Oct 2;13(1):16550
Scientific reports 2023 Oct 2;13(1):16550
TCH-165 attenuates cardiac ischaemia/reperfusion injury by balancing mitochondrial dynamics via increasing proteasome activity.
Gao J, Su HX, Li PB, Shi KN, Li HH
European journal of pharmacology 2023 Oct 15;957:176011
European journal of pharmacology 2023 Oct 15;957:176011
Endoplasmic reticulum stress induced by turbulence of mitochondrial fusion and fission was involved in stressed cardiomyocyte injury.
Zhang S, Li Y, Zhu W, Zhang L, Lei L, Tian X, Chen K, Shi W, Cong B
Journal of cellular and molecular medicine 2023 Nov;27(21):3313-3325
Journal of cellular and molecular medicine 2023 Nov;27(21):3313-3325
FGD5-AS1/miR-5590-3p/PINK1 induces Lenvatinib resistance in hepatocellular carcinoma.
Song M, Ma L, Shen C, Liu W, Zhang P, Bi R, Zhao C
Cellular signalling 2023 Nov;111:110828
Cellular signalling 2023 Nov;111:110828
Schisandrin B Alleviates Renal Tubular Cell Epithelial-Mesenchymal Transition and Mitochondrial Dysfunction by Kielin/Chordin-like Protein Upregulation via Akt Pathway Inactivation and Adenosine 5'-Monophosphate (AMP)-Activated Protein Kinase Pathway Activation in Diabetic Kidney Disease.
Liu W, Li F, Guo D, Du C, Zhao S, Li J, Yan Z, Hao J
Molecules (Basel, Switzerland) 2023 Nov 29;28(23)
Molecules (Basel, Switzerland) 2023 Nov 29;28(23)
Low-dose atorvastatin protects skeletal muscle mitochondria in high-fat diet-fed mice with mitochondrial autophagy inhibition and fusion enhancement.
Zheng P, Zhang Q, Ma W, Hu R, Gu Y, Bian Z, Yang D, Chen X, Wu H
European journal of pharmacology 2023 Nov 15;959:176085
European journal of pharmacology 2023 Nov 15;959:176085
Sodium Sulfite-Triggered Hepatocyte Ferroptosis via mtROS/Lysosomal Membrane Permeabilization-Mediated Lysosome Iron Efflux.
Liu M, Lu J, Chen Y, Zhang S, Guo J, Guan S
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16310-16322
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16310-16322
Alpha lipoamide inhibits diabetic kidney fibrosis via improving mitochondrial function and regulating RXRα expression and activation.
Zhang HF, Liu HM, Xiang JY, Zhou XC, Wang D, Chen RY, Tan WL, Liang LQ, Liu LL, Shi MJ, Zhang F, Xiao Y, Zhou YX, Zhang T, Tang L, Guo B, Wang YY
Acta pharmacologica Sinica 2023 May;44(5):1051-1065
Acta pharmacologica Sinica 2023 May;44(5):1051-1065
AdipoRon mitigates tau pathology and restores mitochondrial dynamics via AMPK-related pathway in a mouse model of Alzheimer's disease.
Wang C, Chang Y, Zhu J, Wu Y, Jiang X, Zheng S, Li G, Ma R
Experimental neurology 2023 May;363:114355
Experimental neurology 2023 May;363:114355
miR-27a-3p relieves heat stress-induced mitochondrial damage and aberrant milk protein synthesis through MEK/ERK pathway in BMECs.
Wang Y, Wu J, Xia SW, Zhao F, Ding Q, Ye XM, Zhong JF, Chen KL, Wang HL
Cell stress & chaperones 2023 May;28(3):265-274
Cell stress & chaperones 2023 May;28(3):265-274
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
Zhou Y, Liu L, Jin B, Wu Y, Xu L, Chang X, Hu L, Wang G, Huang Y, Song L, Zhang T, Wang Y, Xiao Y, Zhang F, Shi M, Liu L, Wang T, Yan R, Guo B
Diabetes 2023 May 1;72(5):611-626
Diabetes 2023 May 1;72(5):611-626
miR-124-3p improves mitochondrial function of renal tubular epithelial cells in db/db mice.
Liang L, Wo C, Yuan Y, Cao H, Tan W, Zhou X, Wang D, Chen R, Shi M, Zhang F, Xiao Y, Liu L, Zhou Y, Zhang T, Wang Y, Guo B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22794
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22794
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
Chen L, Mao M, Liu D, Liu W, Wang Y, Xie L, Deng Y, Lin Y, Xu Y, Zhong X, Cao W
International immunopharmacology 2023 Mar;116:109648
International immunopharmacology 2023 Mar;116:109648
Empagliflozin ameliorates cardiac dysfunction in heart failure mice via regulating mitochondrial dynamics.
Lyu Y, Huo J, Jiang W, Yang W, Wang S, Zhang S, Cheng Y, Jiang Z, Shan Q
European journal of pharmacology 2023 Mar 5;942:175531
European journal of pharmacology 2023 Mar 5;942:175531
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury.
Zhang J, Zhang M, Huo XK, Ning J, Yu ZL, Morisseau C, Sun CP, Hammock BD, Ma XC
ACS central science 2023 Mar 22;9(3):440-456
ACS central science 2023 Mar 22;9(3):440-456
MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model.
Shahin S, Lu B, Zhou Y, Xu H, Chetsawang J, Baloh RH, Wang S
iScience 2023 Mar 17;26(3):106270
iScience 2023 Mar 17;26(3):106270
BNP protects against diabetic cardiomyopathy by promoting Opa1-mediated mitochondrial fusion via activating the PKG-STAT3 pathway.
Chang P, Zhang X, Zhang J, Wang J, Wang X, Li M, Wang R, Yu J, Fu F
Redox biology 2023 Jun;62:102702
Redox biology 2023 Jun;62:102702
Genetic deletion of skeletal muscle iPLA(2)γ results in mitochondrial dysfunction, muscle atrophy and alterations in whole-body energy metabolism.
Moon SH, Dilthey BG, Guan S, Sims HF, Pittman SK, Keith AL, Jenkins CM, Weihl CC, Gross RW
iScience 2023 Jun 16;26(6):106895
iScience 2023 Jun 16;26(6):106895
High-fat diet causes mitochondrial damage and downregulation of mitofusin-2 and optic atrophy-1 in multiple organs.
Zheng P, Ma W, Gu Y, Wu H, Bian Z, Liu N, Yang D, Chen X
Journal of clinical biochemistry and nutrition 2023 Jul;73(1):61-76
Journal of clinical biochemistry and nutrition 2023 Jul;73(1):61-76
RINT1 deficiency disrupts lipid metabolism and underlies a complex hereditary spastic paraplegia.
Launay N, Ruiz M, Planas-Serra L, Verdura E, Rodríguez-Palmero A, Schlüter A, Goicoechea L, Guilera C, Casas J, Campelo F, Jouanguy E, Casanova JL, Boespflug-Tanguy O, Vazquez Cancela M, Gutiérrez-Solana LG, Casasnovas C, Area-Gomez E, Pujol A
The Journal of clinical investigation 2023 Jul 17;133(14)
The Journal of clinical investigation 2023 Jul 17;133(14)
Bavachin and Corylifol A Improve Muscle Atrophy by Enhancing Mitochondria Quality Control in Type 2 Diabetic Mice.
Yeon MH, Seo E, Lee JH, Jun HS
Antioxidants (Basel, Switzerland) 2023 Jan 6;12(1)
Antioxidants (Basel, Switzerland) 2023 Jan 6;12(1)
N-acetyl-L-cysteine alleviates FUNDC1-mediated mitophagy by regulating mitochondrial dynamics in type 1 diabetic nephropathy canine.
Ma F, Li H, Huo H, Han Q, Liao J, Zhang H, Li Y, Pan J, Hu L, Guo J, Tang Z
Life sciences 2023 Jan 15;313:121278
Life sciences 2023 Jan 15;313:121278
Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF-κB pathway due to mitochondrial damage.
Woo JH, Seo HJ, Lee JY, Lee I, Jeon K, Kim B, Lee K
Particle and fibre toxicology 2023 Jan 10;20(1):2
Particle and fibre toxicology 2023 Jan 10;20(1):2
Adaptive exhaustion during prolonged intermittent hypoxia causes dysregulated skeletal muscle protein homeostasis.
Attaway AH, Bellar A, Mishra S, Karthikeyan M, Sekar J, Welch N, Musich R, Singh SS, Kumar A, Menon A, King J, Langen R, Webster J, Scheraga RG, Rochon K, Mears J, Naga Prasad SV, Hatzoglou M, Chakraborty AA, Dasarathy S
The Journal of physiology 2023 Feb;601(3):567-606
The Journal of physiology 2023 Feb;601(3):567-606
Non-Lethal Concentrations of CdCl(2) Cause Marked Alternations in Cellular Stress Responses within Exposed Sertoli Cell Line.
Man Y, Liu Y, Xiong C, Zhang Y, Zhang L
Toxics 2023 Feb 9;11(2)
Toxics 2023 Feb 9;11(2)
Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation.
He Y, Ji Z, Gong Y, Fan L, Xu P, Chen X, Miao J, Zhang K, Zhang W, Ma P, Zhao H, Cheng C, Wang D, Wang J, Jing N, Liu K, Zhang P, Dong B, Zhuang G, Fu Y, Xue W, Gao WQ, Zhu HH
Cell reports 2023 Feb 28;42(2):112033
Cell reports 2023 Feb 28;42(2):112033
MiR-130a-3p regulates FUNDC1-mediated mitophagy by targeting GJA1 in myocardial ischemia/reperfusion injury.
Yan Y, Tian LY, Jia Q, Han Y, Tian Y, Chen HN, Cui SJ, Xi J, Yao YM, Zhao XJ
Cell death discovery 2023 Feb 25;9(1):77
Cell death discovery 2023 Feb 25;9(1):77
Mitofusin 1 and 2 differentially regulate mitochondrial function underlying Ca(2+) signaling and proliferation in rat aortic smooth muscle cells.
Inagaki S, Suzuki Y, Kawasaki K, Kondo R, Imaizumi Y, Yamamura H
Biochemical and biophysical research communications 2023 Feb 19;645:137-146
Biochemical and biophysical research communications 2023 Feb 19;645:137-146
SIRT3 promotes metabolic maturation of human iPSC-derived cardiomyocytes via OPA1-controlled mitochondrial dynamics.
Wang R, Xu H, Tan B, Yi Q, Sun Y, Xiang H, Chen T, Liu H, Xie Q, Wang L, Tian J, Zhu J
Free radical biology & medicine 2023 Feb 1;195:270-282
Free radical biology & medicine 2023 Feb 1;195:270-282
SIRT3-dependent mitochondrial redox homeostasis mitigates CHK1 inhibition combined with gemcitabine treatment induced cardiotoxicity in hiPSC-CMs and mice.
Chen JW, Shan TK, Wei TW, Jiang QQ, Du C, Gu LF, Yang TT, Zhou LH, Wang SB, Bao YL, Wang H, Ji Y, Xie LP, Gu AH, Sun CQ, Wang QM, Wang LS
Archives of toxicology 2023 Dec;97(12):3209-3226
Archives of toxicology 2023 Dec;97(12):3209-3226
Non-steroidal mineralocorticoid receptor antagonist finerenone ameliorates mitochondrial dysfunction via PI3K/Akt/eNOS signaling pathway in diabetic tubulopathy.
Yao L, Liang X, Liu Y, Li B, Hong M, Wang X, Chen B, Liu Z, Wang P
Redox biology 2023 Dec;68:102946
Redox biology 2023 Dec;68:102946
BNIP3 overexpression may promote myeloma cell apoptosis by enhancing sensitivity to bortezomib via the p38 MAPK pathway.
Xiao P, Chen X, Dong Z, Fan W, Chen Y, Su J, Wang Q, Ma L
Hematology (Amsterdam, Netherlands) 2023 Dec;28(1):2231739
Hematology (Amsterdam, Netherlands) 2023 Dec;28(1):2231739
Zearalenone promotes porcine ESCs apoptosis by enhancing Drp1-mediated mitochondrial fragmentation and activating the JNK pathway.
Hai S, Zhao J, Chen C, Wang C, Ma L, Rahman SU, Zhao C, Feng S, Wu J, Wang X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114110
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114110
Lactate Mediates High-Intensity Interval Training-Induced Promotion of Hippocampal Mitochondrial Function through the GPR81-ERK1/2 Pathway.
Shang Q, Bian X, Zhu L, Liu J, Wu M, Lou S
Antioxidants (Basel, Switzerland) 2023 Dec 7;12(12)
Antioxidants (Basel, Switzerland) 2023 Dec 7;12(12)
Ramelteon attenuates renal ischemia and reperfusion injury through reducing mitochondrial fission and fusion and inflammation.
Chen P, Liu W, Wei Y
Translational andrology and urology 2023 Dec 31;12(12):1859-1870
Translational andrology and urology 2023 Dec 31;12(12):1859-1870
The Binding of HSPA8 and Mitochondrial ALDH2 Mediates Oxygen-Glucose Deprivation-Induced Fibroblast Senescence.
Hui W, Song T, Yu L, Chen X
Antioxidants (Basel, Switzerland) 2023 Dec 25;13(1)
Antioxidants (Basel, Switzerland) 2023 Dec 25;13(1)
The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cells.
Cheng J, Wang Y, Yin L, Liang W, Zhang J, Ma C, Zhang Y, Liu B, Wang J, Zhao W, Li M, Wei L
mBio 2023 Dec 19;14(6):e0148023
mBio 2023 Dec 19;14(6):e0148023
Inhibition of the lncRNA 585189 prevents podocyte injury and mitochondria dysfunction by promoting hnRNP A1 and SIRT1 in diabetic nephropathy.
Chen H, Liu Y, Zhang T, Huang T, Lang Y, Sheng Q, Liu Y, Kong Z, Gao Y, Lu S, Yang M, Li X, Wang R, Lv Z
Molecular and cellular endocrinology 2023 Dec 1;578:112065
Molecular and cellular endocrinology 2023 Dec 1;578:112065
Ubiquitination of Ku70 by Parkin promotes apoptosis of lens epithelial cells.
Zhang W, Wu A, Zhang G, Ding X, Kang L, Zhou T, Ji M, Guan H
The FEBS journal 2023 Aug;290(15):3828-3842
The FEBS journal 2023 Aug;290(15):3828-3842
Phospholipase A2-activating protein induces mitophagy through anti-apoptotic MCL1-mediated NLRX1 oligomerization.
Zheng Z, Han L, Li Y, Chen Z, Yang W, Liu C, Tao M, Jiang Y, Ke X, Liu Y, Guo X
Biochimica et biophysica acta. Molecular cell research 2023 Aug;1870(6):119487
Biochimica et biophysica acta. Molecular cell research 2023 Aug;1870(6):119487
Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease.
Shi J, Wang W, Sun S, Xu X, Fei J, Zhou Q, Qin C, Ou S, Wu F, Wu FT, Xu T, Bai L, Xie F
iScience 2023 Aug 18;26(8):107312
iScience 2023 Aug 18;26(8):107312
Diosgenin Targets CaMKK2 to Alleviate Type II Diabetic Nephropathy through Improving Autophagy, Mitophagy and Mitochondrial Dynamics.
Zhong Y, Jin R, Luo R, Liu J, Ren L, Zhang Y, Shan Z, Peng X
Nutrients 2023 Aug 11;15(16)
Nutrients 2023 Aug 11;15(16)
Correction: Tang et al. Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop. Nutrients 2022, 14, 1504.
Tang H, Zheng Z, Wang H, Wang L, Zhao G, Wang P
Nutrients 2023 Aug 11;15(16)
Nutrients 2023 Aug 11;15(16)
LDLR heterozygous deletion reduces hamster testicular cholesterol toxicity via AMPK/Sirt1/PGC-1α pathway.
Bai Y, Hei N, Gao M, Dong X, Li M, Jiang S, Zhang L
Toxicology letters 2023 Aug 1;384:30-43
Toxicology letters 2023 Aug 1;384:30-43
Aristolochic acid I exposure triggers ovarian dysfunction by activating NLRP3 inflammasome and affecting mitochondrial homeostasis.
Sun MX, Qiao FX, Xu ZR, Liu YC, Xu CL, Wang HL, Qi ZQ, Liu Y
Free radical biology & medicine 2023 Aug 1;204:313-324
Free radical biology & medicine 2023 Aug 1;204:313-324
Mitochondrial division inhibitor (mdivi-1) inhibits proliferation and epithelial-mesenchymal transition via the NF-κB pathway in thyroid cancer cells.
Zhang L, Sun L, Wang L, Wang J, Wang D, Jiang J, Zhang J, Zhou Q
Toxicology in vitro : an international journal published in association with BIBRA 2023 Apr;88:105552
Toxicology in vitro : an international journal published in association with BIBRA 2023 Apr;88:105552
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
Qiu S, Zhong X, Meng X, Li S, Qian X, Lu H, Cai J, Zhang Y, Wang M, Ye Z, Zhang H, Gao P
Cell research 2023 Apr;33(4):299-311
Cell research 2023 Apr;33(4):299-311
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction.
Guo Y, Zhang H, Yan C, Shen B, Zhang Y, Guo X, Sun S, Yu F, Yan J, Liu R, Zhang Q, Zhang D, Liu H, Liu Y, Zhang Y, Li W, Qin J, Lv H, Wang Z, Yuan Y, Yang JF, Zhong YT, Gao S, Zhou B, Liu L, Kong D, Hao X, Hu J, Chen Q
Nature chemical biology 2023 Apr;19(4):468-477
Nature chemical biology 2023 Apr;19(4):468-477
HIGD2A silencing impairs hepatocellular carcinoma growth via inhibiting mitochondrial function and the MAPK/ERK pathway.
Huang K, Liu Z, Xie Z, Li X, Zhang H, Chen Y, Wang Y, Lin Z, Li C, Liu H, Zhang X
Journal of translational medicine 2023 Apr 12;21(1):253
Journal of translational medicine 2023 Apr 12;21(1):253
Molybdenum and Cadmium Co-induce Mitochondrial Quality Control Disorder via FUNDC1-Mediated Mitophagy in Sheep Kidney.
Wu Y, Yang F, Zhou G, Wang Q, Xing C, Bai H, Yi X, Xiong Z, Yang S, Cao H
Frontiers in veterinary science 2022;9:842259
Frontiers in veterinary science 2022;9:842259
Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2.
Wang P, Zhang S, Liu W, Chen S, Lv X, Hu B, Shao Z
Oxidative medicine and cellular longevity 2022;2022:7531788
Oxidative medicine and cellular longevity 2022;2022:7531788
Blockage of Fibronectin 1 Ameliorates Myocardial Ischemia/Reperfusion Injury in Association with Activation of AMP-LKB1-AMPK Signaling Pathway.
Zhang YL, Li PB, Han X, Zhang B, Li HH
Oxidative medicine and cellular longevity 2022;2022:6196173
Oxidative medicine and cellular longevity 2022;2022:6196173
Rhein Ameliorates Cognitive Impairment in an APP/PS1 Transgenic Mouse Model of Alzheimer's Disease by Relieving Oxidative Stress through Activating the SIRT1/PGC-1α Pathway.
Yin Z, Gao D, Du K, Han C, Liu Y, Wang Y, Gao X
Oxidative medicine and cellular longevity 2022;2022:2524832
Oxidative medicine and cellular longevity 2022;2022:2524832
Appropriate Dose of Dapagliflozin Improves Cardiac Outcomes by Normalizing Mitochondrial Fission and Reducing Cardiomyocyte Apoptosis After Acute Myocardial Infarction.
Fan ZG, Xu Y, Chen X, Ji MY, Ma GS
Drug design, development and therapy 2022;16:2017-2030
Drug design, development and therapy 2022;16:2017-2030
Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.
Jiang XL, Tai H, Xiao XS, Zhang SY, Cui SC, Qi SB, Hu DD, Zhang LN, Kuang JS, Meng XS, Li SM
Frontiers in endocrinology 2022;13:962154
Frontiers in endocrinology 2022;13:962154
Mitochonic Acid-5 Inhibits Reactive Oxygen Species Production and Improves Human Chondrocyte Survival by Upregulating SIRT3-Mediated, Parkin-dependent Mitophagy.
Xin R, Xu Y, Long D, Mao G, Liao H, Zhang Z, Kang Y
Frontiers in pharmacology 2022;13:911716
Frontiers in pharmacology 2022;13:911716
Atorvastatin Restores PPARα Inhibition of Lipid Metabolism Disorders by Downregulating miR-21 Expression to Improve Mitochondrial Function and Alleviate Diabetic Nephropathy Progression.
Xiang J, Zhang H, Zhou X, Wang D, Chen R, Tan W, Liang L, Shi M, Zhang F, Xiao Y, Zhou Y, Wang Y, Guo B
Frontiers in pharmacology 2022;13:819787
Frontiers in pharmacology 2022;13:819787
Grape seed proanthocyanidin extract targets p66Shc to regulate mitochondrial biogenesis and dynamics in diabetic kidney disease.
Song Y, Yu H, Sun Q, Pei F, Xia Q, Gao Z, Li X
Frontiers in pharmacology 2022;13:1035755
Frontiers in pharmacology 2022;13:1035755
COA3 overexpression promotes non-small cell lung cancer metastasis by reprogramming glucose metabolism.
Lin H, Gao Y, Sun K, Zhang Q, Li Y, Chen M, Jin F
American journal of cancer research 2022;12(8):3662-3678
American journal of cancer research 2022;12(8):3662-3678
Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.
Liang S, Zhu C, Suo C, Wei H, Yu Y, Gu X, Chen L, Yuan M, Shen S, Li S, Sun L, Gao P
Frontiers in oncology 2022;12:857968
Frontiers in oncology 2022;12:857968
Scutellarin Protects Against Mitochondrial Reactive Oxygen Species-Dependent NLRP3 Inflammasome Activation to Attenuate Intervertebral Disc Degeneration.
Wang Z, Zhang P, Zhao Y, Yu F, Wang S, Liu K, Cheng X, Shi J, He Q, Xia Y, Cheng L
Frontiers in bioengineering and biotechnology 2022;10:883118
Frontiers in bioengineering and biotechnology 2022;10:883118
Mitoquinone mitigates paraquat-induced A549 lung epithelial cell injury by promoting MFN1/MFN2-mediated mitochondrial fusion.
Liu C, Sun Z, Wang M, Yang Z, Zhang W, Ren Y, Han X, Zhang B, Yao M, Nie S
Journal of biochemical and molecular toxicology 2022 Sep;36(9):e23127
Journal of biochemical and molecular toxicology 2022 Sep;36(9):e23127
Battery wastewater induces nephrotoxicity via disordering the mitochondrial dynamics.
Yi J, Liao J, Bai T, Wang B, Yangzom C, Ahmed Z, Mehmood K, Abbas RZ, Li Y, Tang Z, Zhang H
Chemosphere 2022 Sep;303(Pt 1):135018
Chemosphere 2022 Sep;303(Pt 1):135018
Mannose inhibits the growth of prostate cancer through a mitochondrial mechanism.
Deng YL, Liu R, Cai ZD, Han ZD, Feng YF, Cai SH, Chen QB, Zhu JG, Zhong WD
Asian journal of andrology 2022 Sep-Oct;24(5):540-548
Asian journal of andrology 2022 Sep-Oct;24(5):540-548
Protective Effect of Manganese on Apoptosis and Mitochondrial Function of Heat-Stressed Primary Chick Embryonic Myocardial Cells.
Wang R, Shi Z, Li J, Tang D, Qin S, Guo Y
Biological trace element research 2022 Oct;200(10):4419-4429
Biological trace element research 2022 Oct;200(10):4419-4429
UBXD8 mediates mitochondria-associated degradation to restrain apoptosis and mitophagy.
Zheng J, Cao Y, Yang J, Jiang H
EMBO reports 2022 Oct 6;23(10):e54859
EMBO reports 2022 Oct 6;23(10):e54859
Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF.
Jiang XL, Tai H, Kuang JS, Zhang JY, Cui SC, Lu YX, Qi SB, Zhang SY, Li SM, Chen JP, Meng XS
Aging 2022 Oct 27;14(20):8321-8345
Aging 2022 Oct 27;14(20):8321-8345
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats.
Tai H, Cui XZ, He J, Lan ZM, Li SM, Li LB, Yao SC, Jiang XL, Meng XS, Kuang JS
Aging 2022 Oct 20;14(20):8302-8320
Aging 2022 Oct 20;14(20):8302-8320
Integrated Analysis of Transcriptome and microRNA Profile Reveals the Toxicity of Euphorbia Factors toward Human Colon Adenocarcinoma Cell Line Caco-2.
Zou L, Bao W, Gao Y, Chen M, Wu Y, Wang S, Li C, Zhang J, Zhang D, Wang Q, Zhu A
Molecules (Basel, Switzerland) 2022 Oct 16;27(20)
Molecules (Basel, Switzerland) 2022 Oct 16;27(20)
Anti-ANGPTL3-FLD monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage.
Lv Q, Han X, Ni J, Ma Q, Dai R, Liu J, Liu J, Zhai Y, Shen Q, Sun L, Liu H, Rao J, Xu H
Cell death & disease 2022 Oct 13;13(10):867
Cell death & disease 2022 Oct 13;13(10):867
Cadmium-induced apoptosis of Leydig cells is mediated by excessive mitochondrial fission and inhibition of mitophagy.
Yi L, Shang XJ, Lv L, Wang Y, Zhang J, Quan C, Shi Y, Liu Y, Zhang L
Cell death & disease 2022 Nov 5;13(11):928
Cell death & disease 2022 Nov 5;13(11):928
Diosgenin Ameliorated Type II Diabetes-Associated Nonalcoholic Fatty Liver Disease through Inhibiting De Novo Lipogenesis and Improving Fatty Acid Oxidation and Mitochondrial Function in Rats.
Zhong Y, Li Z, Jin R, Yao Y, He S, Lei M, Wang X, Shi C, Gao L, Peng X
Nutrients 2022 Nov 24;14(23)
Nutrients 2022 Nov 24;14(23)
COX7A1 enhances the sensitivity of human NSCLC cells to cystine deprivation-induced ferroptosis via regulating mitochondrial metabolism.
Feng Y, Xu J, Shi M, Liu R, Zhao L, Chen X, Li M, Zhao Y, Chen J, Du W, Liu P
Cell death & disease 2022 Nov 23;13(11):988
Cell death & disease 2022 Nov 23;13(11):988
O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.
Cao Y, Zhang M, Li Y, Lu J, Zhou W, Li X, Shi H, Xu B, Li S
International journal of molecular sciences 2022 Nov 22;23(23)
International journal of molecular sciences 2022 Nov 22;23(23)
Gestational Intermittent Hypoxia Induces Mitochondrial Impairment in the Geniohyoid Muscle of Offspring Rats.
Wongkitikamjorn W, Hosomichi J, Wada E, Maeda H, Satrawaha S, Hong H, Hayashi YK, Yoshida KI, Ono T
Cureus 2022 May;14(5):e25088
Cureus 2022 May;14(5):e25088
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.
Li C, Li L, Yang M, Yang J, Zhao C, Han Y, Zhao H, Jiang N, Wei L, Xiao Y, Liu Y, Xiong X, Xi Y, Luo S, Deng F, Chen W, Yuan S, Zhu X, Xiao L, Sun L
Diabetes 2022 May 1;71(5):1034-1050
Diabetes 2022 May 1;71(5):1034-1050
Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway.
Shen R, Yang K, Cheng X, Guo C, Xing X, Sun H, Liu D, Liu X, Wang D
Environmental pollution (Barking, Essex : 1987) 2022 May 1;300:118986
Environmental pollution (Barking, Essex : 1987) 2022 May 1;300:118986
HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3.
Hu B, Wang P, Zhang S, Liu W, Lv X, Shi D, Zhao L, Liu H, Wang B, Chen S, Shao Z
Experimental & molecular medicine 2022 Mar;54(3):309-323
Experimental & molecular medicine 2022 Mar;54(3):309-323
Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.
Li Y, Zhu Y, Chu B, Liu N, Chen S, Wang J
Veterinary microbiology 2022 Mar;266:109367
Veterinary microbiology 2022 Mar;266:109367
The effect of mitochondrial fusion on chondrogenic differentiation of cartilage progenitor/stem cells via Notch2 signal pathway.
Moqbel SAA, Zeng R, Ma D, Xu L, Lin C, He Y, Ma C, Xu K, Ran J, Jiang L, Wu L
Stem cell research & therapy 2022 Mar 25;13(1):127
Stem cell research & therapy 2022 Mar 25;13(1):127
Carbon tetrachloride induced mitochondrial division, respiratory chain damage, abnormal intracellular [H(+)] and apoptosis are due to the activation of 5-HT degradation system in hepatocytes.
Zhang Y, Liang X, Guan J, Jin J, Zhang Y, Xu F, Fu J
Toxicology and applied pharmacology 2022 Mar 15;439:115929
Toxicology and applied pharmacology 2022 Mar 15;439:115929
Autophagy and mitochondrial dynamics contribute to the protective effect of diosgenin against 3-MCPD induced kidney injury.
Zhong Y, Sun D, Yao Y, Liu Q, Guo T, Wang X, Peng X
Chemico-biological interactions 2022 Mar 1;355:109850
Chemico-biological interactions 2022 Mar 1;355:109850
Long-term exercise pre-training attenuates Alzheimer's disease-related pathology in a transgenic rat model of Alzheimer's disease.
Yang L, Wu C, Li Y, Dong Y, Wu CY, Lee RH, Brann DW, Lin HW, Zhang Q
GeroScience 2022 Jun;44(3):1457-1477
GeroScience 2022 Jun;44(3):1457-1477
A possible new activator of PI3K-Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction.
Tai H, Tong YJ, Yu R, Yu Y, Yao SC, Li LB, Liu Y, Cui XZ, Kuang JS, Meng XS, Jiang XL
Journal of cellular and molecular medicine 2022 Jun;26(12):3423-3445
Journal of cellular and molecular medicine 2022 Jun;26(12):3423-3445
ManNAc protects against podocyte pyroptosis via inhibiting mitochondrial damage and ROS/NLRP3 signaling pathway in diabetic kidney injury model.
Gao Y, Ma Y, Xie D, Jiang H
International immunopharmacology 2022 Jun;107:108711
International immunopharmacology 2022 Jun;107:108711
Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.
Li Y, Yang L, Hu F, Xu J, Ye J, Liu S, Wang L, Zhuo M, Ran B, Zhang H, Ye J, Xiao J
ACS applied materials & interfaces 2022 Jun 8;14(22):25155-25172
ACS applied materials & interfaces 2022 Jun 8;14(22):25155-25172
Heterozygous PRKN mutations are common but do not increase the risk of Parkinson's disease.
Zhu W, Huang X, Yoon E, Bandres-Ciga S, Blauwendraat C, Billingsley KJ, Cade JH, Wu BP, Williams VH, Schindler AB, Brooks J, Gibbs JR, Hernandez DG, Ehrlich D, Singleton AB, Narendra DP
Brain : a journal of neurology 2022 Jun 30;145(6):2077-2091
Brain : a journal of neurology 2022 Jun 30;145(6):2077-2091
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Lu J, Fu S, Dai J, Hu J, Li S, Ji H, Wang Z, Yu J, Bao J, Xu B, Guo J, Yang H
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
Identification of Mitofusin 1 and Complement Component 1q Subcomponent Binding Protein as Mitochondrial Targets in Systemic Lupus Erythematosus.
Becker YLC, Gagné JP, Julien AS, Lévesque T, Allaeys I, Gougeard N, Rubio V, Boisvert FM, Jean D, Wagner E, Poirier GG, Fortin PR, Boilard É
Arthritis & rheumatology (Hoboken, N.J.) 2022 Jul;74(7):1193-1203
Arthritis & rheumatology (Hoboken, N.J.) 2022 Jul;74(7):1193-1203
The mitochondrial protein Sideroflexin 3 (SFXN3) influences neurodegeneration pathways in vivo.
Ledahawsky LM, Terzenidou ME, Edwards R, Kline RA, Graham LC, Eaton SL, van der Hoorn D, Chaytow H, Huang YT, Groen EJN, Motyl AAL, Lamont DJ, Tokatlidis K, Wishart TM, Gillingwater TH
The FEBS journal 2022 Jul;289(13):3894-3914
The FEBS journal 2022 Jul;289(13):3894-3914
Targeting Tau Mitigates Mitochondrial Fragmentation and Oxidative Stress in Amyotrophic Lateral Sclerosis.
Petrozziello T, Bordt EA, Mills AN, Kim SE, Sapp E, Devlin BA, Obeng-Marnu AA, Farhan SMK, Amaral AC, Dujardin S, Dooley PM, Henstridge C, Oakley DH, Neueder A, Hyman BT, Spires-Jones TL, Bilbo SD, Vakili K, Cudkowicz ME, Berry JD, DiFiglia M, Silva MC, Haggarty SJ, Sadri-Vakili G
Molecular neurobiology 2022 Jan;59(1):683-702
Molecular neurobiology 2022 Jan;59(1):683-702
Herceptin induces ferroptosis and mitochondrial dysfunction in H9c2 cells.
Sun L, Wang H, Yu S, Zhang L, Jiang J, Zhou Q
International journal of molecular medicine 2022 Feb;49(2)
International journal of molecular medicine 2022 Feb;49(2)
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
Wang N, Huang R, Yang K, He Y, Gao Y, Dong D
Journal of cellular and molecular medicine 2022 Feb;26(3):893-912
Journal of cellular and molecular medicine 2022 Feb;26(3):893-912
Attenuates of NAD(+) impair BMSC osteogenesis and fracture repair through OXPHOS.
Li B, Shi Y, Liu M, Wu F, Hu X, Yu F, Wang C, Ye L
Stem cell research & therapy 2022 Feb 22;13(1):77
Stem cell research & therapy 2022 Feb 22;13(1):77
Protein C receptor maintains cancer stem cell properties via activating lipid synthesis in nasopharyngeal carcinoma.
Zhang P, He Q, Wang Y, Zhou G, Chen Y, Tang L, Zhang Y, Hong X, Mao Y, He Q, Yang X, Liu N, Ma J
Signal transduction and targeted therapy 2022 Feb 16;7(1):46
Signal transduction and targeted therapy 2022 Feb 16;7(1):46
Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.
Xu Z, Fu T, Guo Q, Zhou D, Sun W, Zhou Z, Chen X, Zhang J, Liu L, Xiao L, Yin Y, Jia Y, Pang E, Chen Y, Pan X, Fang L, Zhu MS, Fei W, Lu B, Gan Z
Nature communications 2022 Feb 16;13(1):894
Nature communications 2022 Feb 16;13(1):894
Cdk5 Promotes Mitochondrial Fission via Drp1 Phosphorylation at S616 in Chronic Ethanol Exposure-Induced Cognitive Impairment.
Liu D, Li J, Rong X, Li J, Peng Y, Shen Q
Molecular neurobiology 2022 Dec;59(12):7075-7094
Molecular neurobiology 2022 Dec;59(12):7075-7094
GABA regulates IL-1β production in macrophages.
Fu J, Han Z, Wu Z, Xia Y, Yang G, Yin Y, Ren W
Cell reports 2022 Dec 6;41(10):111770
Cell reports 2022 Dec 6;41(10):111770
Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function.
Jang W, Puchkov D, Samsó P, Liang Y, Nadler-Holly M, Sigrist SJ, Kintscher U, Liu F, Mamchaoui K, Mouly V, Haucke V
Science (New York, N.Y.) 2022 Dec 16;378(6625):eabq5209
Science (New York, N.Y.) 2022 Dec 16;378(6625):eabq5209
Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD(+) regeneration in KRas-mutant lung adenocarcinoma.
Sessions DT, Kim KB, Kashatus JA, Churchill N, Park KS, Mayo MW, Sesaki H, Kashatus DF
Cell reports 2022 Dec 13;41(11):111818
Cell reports 2022 Dec 13;41(11):111818
HIF-1α mediates renal fibrosis by regulating metabolic remodeling of renal tubule epithelial cells.
Liu D, Sun H, Li K, Zhao Z, Liu Z, Zhang G, Ge Y, Zhang J, Wang D, Leng Y
Biochemical and biophysical research communications 2022 Aug 27;618:15-23
Biochemical and biophysical research communications 2022 Aug 27;618:15-23
A pivotal role of selective autophagy in mitochondrial quality control: Implications for zinc oxide nanoparticles induced neurotoxicity.
Wang L, Duan Z, Liang M, Wang C, Liang T, Sun L, Yan C, Li Q, Liang T
Chemico-biological interactions 2022 Aug 25;363:110003
Chemico-biological interactions 2022 Aug 25;363:110003
Reduced VDAC1, Maintained Mitochondrial Dynamics and Enhanced Mitochondrial Biogenesis in a Transgenic Tau Mouse Model of Alzheimer's Disease.
Vijayan M, Reddy PH
International journal of molecular sciences 2022 Aug 2;23(15)
International journal of molecular sciences 2022 Aug 2;23(15)
Baicalein suppresses high glucose-induced inflammation and apoptosis in trophoblasts by targeting the miRNA-17-5p-Mfn1/2-NF-κB pathway.
Li J, Wang Y, Wu T, Li S, Sun YN, Liu ZH
Placenta 2022 Apr;121:126-136
Placenta 2022 Apr;121:126-136
Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.
Li Y, Zhu Y, Chu B, Liu N, Chen S, Wang J, Zou Y
International journal of molecular sciences 2022 Apr 28;23(9)
International journal of molecular sciences 2022 Apr 28;23(9)
Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress.
Zeng HF, Xu J, Wang XL, Li SJ, Han ZY
Ecotoxicology and environmental safety 2022 Apr 15;235:113441
Ecotoxicology and environmental safety 2022 Apr 15;235:113441
Phosphorylation of Dynamin-Related Protein 1 (DRP1) Regulates Mitochondrial Dynamics and Skeletal Muscle Wasting in Cancer Cachexia.
Mao X, Gu Y, Sui X, Shen L, Han J, Wang H, Xi Q, Zhuang Q, Meng Q, Wu G
Frontiers in cell and developmental biology 2021;9:673618
Frontiers in cell and developmental biology 2021;9:673618
Mitochondrial Fusion Potentially Regulates a Metabolic Change in Tibetan Chicken Embryonic Brain During Hypoxia.
Tang Q, Ding C, Xu Q, Bai Y, Xu Q, Wang K, Fang M
Frontiers in cell and developmental biology 2021;9:585166
Frontiers in cell and developmental biology 2021;9:585166
Vanadium Induces Oxidative Stress and Mitochondrial Quality Control Disorder in the Heart of Ducks.
Xiong Z, Xing C, Xu T, Yang Y, Liu G, Hu G, Cao H, Zhang C, Guo X, Yang F
Frontiers in veterinary science 2021;8:756534
Frontiers in veterinary science 2021;8:756534
Secreted Frizzled-Related Protein 5 Protects Against Cardiac Rupture and Improves Cardiac Function Through Inhibiting Mitochondrial Dysfunction.
Huang X, Yan Y, Zheng W, Ma Y, Wang X, Gong W, Nie S
Frontiers in cardiovascular medicine 2021;8:682409
Frontiers in cardiovascular medicine 2021;8:682409
Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats.
Tai H, Jiang XL, Song N, Xiao HH, Li Y, Cheng MJ, Yin XM, Chen YR, Yang GL, Jiang XY, Kuang JS, Lan ZM, Jia LQ
Frontiers in medicine 2021;8:617393
Frontiers in medicine 2021;8:617393
RNA-Seq Profiling to Investigate the Mechanism of Qishen Granules on Regulating Mitochondrial Energy Metabolism of Heart Failure in Rats.
He H, Li C, Lu X, Li Y, Li X, Sun X, Tang B, Wu Y, Li C
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5779307
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5779307
Mitochondrial Transplantation Attenuates Cerebral Ischemia-Reperfusion Injury: Possible Involvement of Mitochondrial Component Separation.
Xie Q, Zeng J, Zheng Y, Li T, Ren J, Chen K, Zhang Q, Xie R, Xu F, Zhu J
Oxidative medicine and cellular longevity 2021;2021:1006636
Oxidative medicine and cellular longevity 2021;2021:1006636
Maresin 1 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury via Inhibiting NOX4/ROS/NF-κB Pathway.
Li J, Zhang Z, Wang L, Jiang L, Qin Z, Zhao Y, Su B
Frontiers in pharmacology 2021;12:782660
Frontiers in pharmacology 2021;12:782660
Tortoise Plastron and Deer Antler Gelatin Prevents Against Neuronal Mitochondrial Dysfunction In Vitro: Implication for a Potential Therapy of Alzheimer's Disease.
Cheng D, Yang XJ, Zhang L, Qin ZS, Li WQ, Xu HC, Zhang ZJ
Frontiers in pharmacology 2021;12:690256
Frontiers in pharmacology 2021;12:690256
Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes.
Meng TT, Wang W, Meng FL, Wang SY, Wu HH, Chen JM, Zheng Y, Wang GX, Zhang MX, Li Y, Su GH
Frontiers in physiology 2021;12:650055
Frontiers in physiology 2021;12:650055
Elevated Lactate by High-Intensity Interval Training Regulates the Hippocampal BDNF Expression and the Mitochondrial Quality Control System.
Hu J, Cai M, Shang Q, Li Z, Feng Y, Liu B, Xue X, Lou S
Frontiers in physiology 2021;12:629914
Frontiers in physiology 2021;12:629914
The E3 ubiquitin ligase TRIM31 is involved in cerebral ischemic injury by promoting degradation of TIGAR.
Zeng S, Zhao Z, Zheng S, Wu M, Song X, Li Y, Zheng Y, Liu B, Chen L, Gao C, Liu H
Redox biology 2021 Sep;45:102058
Redox biology 2021 Sep;45:102058
Punicalagin Protects Against Diabetic Cardiomyopathy by Promoting Opa1-Mediated Mitochondrial Fusion via Regulating PTP1B-Stat3 Pathway.
Fu F, Liu C, Shi R, Li M, Zhang M, Du Y, Wang Q, Li J, Wang G, Pei J, Ding M
Antioxidants & redox signaling 2021 Sep;35(8):618-641
Antioxidants & redox signaling 2021 Sep;35(8):618-641
Trimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control.
Zhang W, You B, Qi D, Qiu L, Ripley-Gonzalez JW, Zheng F, Fu S, Li C, Dun Y, Liu S
Scientific reports 2021 Sep 27;11(1):19116
Scientific reports 2021 Sep 27;11(1):19116
Mechanisms of impaired mitochondrial homeostasis and NAD(+) metabolism in a model of mitochondrial heart disease exhibiting redox active iron accumulation.
Chiang S, Braidy N, Maleki S, Lal S, Richardson DR, Huang ML
Redox biology 2021 Oct;46:102038
Redox biology 2021 Oct;46:102038
Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca(2+) homeostasis.
Zhong Y, Jin C, Han J, Zhu J, Liu Q, Sun D, Xia X, Peng X
Cell biology and toxicology 2021 Oct;37(5):795-809
Cell biology and toxicology 2021 Oct;37(5):795-809
SIRT3 protects bovine mammary epithelial cells from heat stress damage by activating the AMPK signaling pathway.
Sun XC, Wang Y, Zeng HF, Xi YM, Lin H, Han ZY, Chen KL
Cell death discovery 2021 Oct 21;7(1):304
Cell death discovery 2021 Oct 21;7(1):304
Melatonin protects against excessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells.
Xie QE, Wang MY, Cao ZP, Du X, Ji DM, Liang D, Cao YX, Liu YJ
Mitochondrion 2021 Nov;61:44-53
Mitochondrion 2021 Nov;61:44-53
Anti-inflammatory and neuroprotective effects of natural cordycepin in rotenone-induced PD models through inhibiting Drp1-mediated mitochondrial fission.
Zhang XL, Huang WM, Tang PC, Sun Y, Zhang X, Qiu L, Yu BC, Zhang XY, Hong YX, He Y, Ge XQ
Neurotoxicology 2021 May;84:1-13
Neurotoxicology 2021 May;84:1-13
The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses.
Hu Y, Chen H, Zhang L, Lin X, Li X, Zhuang H, Fan H, Meng T, He Z, Huang H, Gong Q, Zhu D, Xu Y, He P, Li L, Feng D
Autophagy 2021 May;17(5):1142-1156
Autophagy 2021 May;17(5):1142-1156
LACTB suppresses melanoma progression by attenuating PP1A and YAP interaction.
Ma Y, Wang L, He F, Yang J, Ding Y, Ge S, Fan X, Zhou Y, Xu X, Jia R
Cancer letters 2021 May 28;506:67-82
Cancer letters 2021 May 28;506:67-82
Mitocytosis, a migrasome-mediated mitochondrial quality-control process.
Jiao H, Jiang D, Hu X, Du W, Ji L, Yang Y, Li X, Sho T, Wang X, Li Y, Wu YT, Wei YH, Hu X, Yu L
Cell 2021 May 27;184(11):2896-2910.e13
Cell 2021 May 27;184(11):2896-2910.e13
Conditioned medium from induced pluripotent stem cell-derived mesenchymal stem cells accelerates cutaneous wound healing through enhanced angiogenesis.
Liang X, Lin F, Ding Y, Zhang Y, Li M, Zhou X, Meng Q, Ma X, Wei L, Fan H, Liu Z
Stem cell research & therapy 2021 May 20;12(1):295
Stem cell research & therapy 2021 May 20;12(1):295
AMPK-dependent and -independent coordination of mitochondrial function and muscle fiber type by FNIP1.
Xiao L, Liu J, Sun Z, Yin Y, Mao Y, Xu D, Liu L, Xu Z, Guo Q, Ding C, Sun W, Yang L, Zhou Z, Zhou D, Fu T, Zhou W, Zhu Y, Chen XW, Li JZ, Chen S, Xie X, Gan Z
PLoS genetics 2021 Mar;17(3):e1009488
PLoS genetics 2021 Mar;17(3):e1009488
Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.
Tai H, Jiang XL, Lan ZM, Li Y, Kong L, Yao SC, Song N, Lv MJ, Wu J, Yang P, Xiao XS, Yang GL, Kuang JS, Jia LQ
BMC complementary medicine and therapies 2021 Mar 22;21(1):100
BMC complementary medicine and therapies 2021 Mar 22;21(1):100
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
Zhang L, Cao H, Tao H, Yang J, Gong W, Hu Q
Experimental and therapeutic medicine 2021 Jul;22(1):696
Experimental and therapeutic medicine 2021 Jul;22(1):696
Vmp1, Vps13D, and Marf/Mfn2 function in a conserved pathway to regulate mitochondria and ER contact in development and disease.
Shen JL, Fortier TM, Zhao YG, Wang R, Burmeister M, Baehrecke EH
Current biology : CB 2021 Jul 26;31(14):3028-3039.e7
Current biology : CB 2021 Jul 26;31(14):3028-3039.e7
Mesenchymal stem cells ameliorate lipid metabolism through reducing mitochondrial damage of hepatocytes in the treatment of post-hepatectomy liver failure.
Wang JL, Ding HR, Pan CY, Shi XL, Ren HZ
Cell death & disease 2021 Jan 21;12(1):111
Cell death & disease 2021 Jan 21;12(1):111
Cdk5-Mediated Phosphorylation of Sirt1 Contributes to Podocyte Mitochondrial Dysfunction in Diabetic Nephropathy.
Wang S, Yang Y, He X, Yang L, Wang J, Xia S, Liu D, Liu S, Yang L, Liu W, Duan H
Antioxidants & redox signaling 2021 Jan 20;34(3):171-190
Antioxidants & redox signaling 2021 Jan 20;34(3):171-190
CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson's disease.
Hu Z, Mao C, Wang H, Zhang Z, Zhang S, Luo H, Tang M, Yang J, Yuan Y, Wang Y, Liu Y, Fan L, Zhang Q, Yao D, Liu F, Schisler JC, Shi C, Xu Y
Aging 2021 Jan 2;13(1):1458-1472
Aging 2021 Jan 2;13(1):1458-1472
OPA1 haploinsufficiency due to a novel splicing variant resulting in mitochondrial dysfunction without mitochondrial DNA depletion.
Sun C, Wu X, Bai HX, Wang C, Liu Z, Yang C, Lu Y, Jiang P
Ophthalmic genetics 2021 Feb;42(1):45-52
Ophthalmic genetics 2021 Feb;42(1):45-52
Nanoparticle-encapsulated antioxidant improves placental mitochondrial function in a sexually dimorphic manner in a rat model of prenatal hypoxia.
Ganguly E, Kirschenman R, Spaans F, Holody CD, Phillips TEJ, Case CP, Cooke CM, Murphy MP, Lemieux H, Davidge ST
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21338
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21338
Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner.
Zhang C, Nie P, Zhou C, Hu Y, Duan S, Gu M, Jiang D, Wang Y, Deng Z, Chen J, Chen S, Wang L
Cell death & disease 2021 Feb 24;12(2):209
Cell death & disease 2021 Feb 24;12(2):209
Caffeine promotes angiogenesis through modulating endothelial mitochondrial dynamics.
Wang LT, He PC, Li AQ, Cao KX, Yan JW, Guo S, Jiang L, Yao L, Dai XY, Feng D, Xu YM, Tan N
Acta pharmacologica Sinica 2021 Dec;42(12):2033-2045
Acta pharmacologica Sinica 2021 Dec;42(12):2033-2045
Possible relationship between mitochondrial changes and oxidative stress under low dose-rate irradiation.
Meng Q, Zaharieva EK, Sasatani M, Kobayashi J
Redox report : communications in free radical research 2021 Dec;26(1):160-169
Redox report : communications in free radical research 2021 Dec;26(1):160-169
Entresto protected the cardiomyocytes and preserved heart function in cardiorenal syndrome rat fed with high-protein diet through regulating the oxidative stress and Mfn2-mediated mitochondrial functional integrity.
Yeh JN, Yue Y, Chu YC, Huang CR, Yang CC, Chiang JY, Yip HK, Guo J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112244
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112244
USP30-AS1 contributes to mitochondrial quality control in glioblastoma cells.
Wang N, Li J, Xin Q, Xu N
Biochemical and biophysical research communications 2021 Dec 3;581:31-37
Biochemical and biophysical research communications 2021 Dec 3;581:31-37
Targeting P2RX1 alleviates renal ischemia/reperfusion injury by preserving mitochondrial dynamics.
Zhuang S, Xia S, Huang P, Wu J, Qu J, Chen R, Sun N, Li D, Wu H, Zhang M, Zhang J, Yuan X, Wang X
Pharmacological research 2021 Aug;170:105712
Pharmacological research 2021 Aug;170:105712
LKB1/AMPKα signaling pathway and mitochondrial fission/fusion dynamics regulate apoptosis induced by 3-chlorpropane-1,2-diol in HEK293 cells.
Jin C, Xue W, Liu Q, Han J, Luo R, Feng J, Liu J, Guo T, Peng X, Hu T
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Aug;154:112350
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Aug;154:112350
Extract of Cynomorium songaricum ameliorates mitochondrial ultrastructure impairments and dysfunction in two different in vitro models of Alzheimer's disease.
Cheng D, Su L, Wang X, Li X, Li L, Hu M, Lu Y
BMC complementary medicine and therapies 2021 Aug 9;21(1):206
BMC complementary medicine and therapies 2021 Aug 9;21(1):206
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
Lei Y, Zhang X, Xu Q, Liu S, Li C, Jiang H, Lin H, Kong E, Liu J, Qi S, Li H, Xu W, Lu K
Developmental cell 2021 Aug 23;56(16):2313-2328.e7
Developmental cell 2021 Aug 23;56(16):2313-2328.e7
Mst1 Knockout Alleviates Mitochondrial Fission and Mitigates Left Ventricular Remodeling in the Development of Diabetic Cardiomyopathy.
Feng X, Wang S, Yang X, Lin J, Man W, Dong Y, Zhang Y, Zhao Z, Wang H, Sun D
Frontiers in cell and developmental biology 2020;8:628842
Frontiers in cell and developmental biology 2020;8:628842
Deletion of Bmal1 Impairs Pancreatic β-Cell Function via Mitochondrial Signaling Pathway.
Ye L, Wu H, Xu W
BioMed research international 2020;2020:9803024
BioMed research international 2020;2020:9803024
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
Deng X, Liu J, Liu L, Sun X, Huang J, Dong J
International journal of biological sciences 2020;16(8):1403-1416
International journal of biological sciences 2020;16(8):1403-1416
A Long-Term Enriched Environment Ameliorates the Accelerated Age-Related Memory Impairment Induced by Gestational Administration of Lipopolysaccharide: Role of Plastic Mitochondrial Quality Control.
Zhuang ZQ, Zhang ZZ, Zhang YM, Ge HH, Sun SY, Zhang P, Chen GH
Frontiers in cellular neuroscience 2020;14:559182
Frontiers in cellular neuroscience 2020;14:559182
Drp1-dependent mitochondrial fission contributes to Cr(VI)-induced mitophagy and hepatotoxicity.
Zhang Y, Ma Y, Xiao Y, Lu C, Xiao F
Ecotoxicology and environmental safety 2020 Oct 15;203:110928
Ecotoxicology and environmental safety 2020 Oct 15;203:110928
PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth.
Guo L, Cui C, Wang J, Yuan J, Yang Q, Zhang P, Su W, Bao R, Ran J, Wu C
Nature communications 2020 Oct 1;11(1):4913
Nature communications 2020 Oct 1;11(1):4913
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
Jiang N, Zhao H, Han Y, Li L, Xiong S, Zeng L, Xiao Y, Wei L, Xiong X, Gao P, Yang M, Liu Y, Sun L
Cell proliferation 2020 Nov;53(11):e12909
Cell proliferation 2020 Nov;53(11):e12909
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.
Ma WQ, Sun XJ, Zhu Y, Liu NF
Cell death & disease 2020 Nov 17;11(11):991
Cell death & disease 2020 Nov 17;11(11):991
Nestin protects podocyte from injury in lupus nephritis by mitophagy and oxidative stress.
Tian Y, Guo H, Miao X, Xu J, Yang R, Zhao L, Liu J, Yang L, Gao F, Zhang W, Liu Q, Sun S, Tian Y, Li H, Huang J, Gu C, Liu S, Feng X
Cell death & disease 2020 May 5;11(5):319
Cell death & disease 2020 May 5;11(5):319
AIM2 promotes the development of non-small cell lung cancer by modulating mitochondrial dynamics.
Qi M, Dai D, Liu J, Li Z, Liang P, Wang Y, Cheng L, Zhan Y, An Z, Song Y, Yang Y, Yan X, Xiao H, Shao H
Oncogene 2020 Mar;39(13):2707-2723
Oncogene 2020 Mar;39(13):2707-2723
NAD(+) precursor modulates post-ischemic mitochondrial fragmentation and reactive oxygen species generation via SIRT3 dependent mechanisms.
Klimova N, Fearnow A, Long A, Kristian T
Experimental neurology 2020 Mar;325:113144
Experimental neurology 2020 Mar;325:113144
Mitochondrial Dynamics Regulation in Skin Fibroblasts from Mitochondrial Disease Patients.
Tokuyama T, Hirai A, Shiiba I, Ito N, Matsuno K, Takeda K, Saito K, Mii K, Matsushita N, Fukuda T, Inatome R, Yanagi S
Biomolecules 2020 Mar 13;10(3)
Biomolecules 2020 Mar 13;10(3)
Fluoride-induced renal dysfunction via respiratory chain complex abnormal expression and fusion elevation in mice.
Wang HW, Zhu SQ, Liu J, Miao CY, Zhang Y, Zhou BH
Chemosphere 2020 Jan;238:124607
Chemosphere 2020 Jan;238:124607
Anti-insulin resistance effects of salidroside through mitochondrial quality control.
You B, Dun Y, Zhang W, Jiang L, Li H, Xie M, Liu Y, Liu S
The Journal of endocrinology 2020 Feb;244(2):383-393
The Journal of endocrinology 2020 Feb;244(2):383-393
Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice.
Wang HW, Liu J, Wei SS, Zhao WP, Zhu SQ, Zhou BH
Chemosphere 2020 Feb;241:125099
Chemosphere 2020 Feb;241:125099
Sodium-glucose cotransporter 2 inhibition attenuates protein overload in renal proximal tubule via suppression of megalin O-GlcNacylation in progressive diabetic nephropathy.
Otomo H, Nara M, Kato S, Shimizu T, Suganuma Y, Sato T, Morii T, Yamada Y, Fujita H
Metabolism: clinical and experimental 2020 Dec;113:154405
Metabolism: clinical and experimental 2020 Dec;113:154405
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
Ma D, Zheng B, Liu HL, Zhao YB, Liu X, Zhang XH, Li Q, Shi WB, Suzuki T, Wen JK
PLoS biology 2020 Aug;18(8):e3000808
PLoS biology 2020 Aug;18(8):e3000808
Fission and fusion machineries converge at ER contact sites to regulate mitochondrial morphology.
Abrisch RG, Gumbin SC, Wisniewski BT, Lackner LL, Voeltz GK
The Journal of cell biology 2020 Apr 6;219(4)
The Journal of cell biology 2020 Apr 6;219(4)
DsbA-L deficiency exacerbates mitochondrial dysfunction of tubular cells in diabetic kidney disease.
Gao P, Yang M, Chen X, Xiong S, Liu J, Sun L
Clinical science (London, England : 1979) 2020 Apr 17;134(7):677-694
Clinical science (London, England : 1979) 2020 Apr 17;134(7):677-694
Propofol Ameliorates H9c2 Cells Apoptosis Induced by Oxygen Glucose Deprivation and Reperfusion Injury via Inhibiting High Levels of Mitochondrial Fusion and Fission.
Zhao L, Zhuang J, Wang Y, Zhou D, Zhao D, Zhu S, Pu J, Zhang H, Yin M, Zhao W, Wang Z, Hong J
Frontiers in pharmacology 2019;10:61
Frontiers in pharmacology 2019;10:61
OPA1 overexpression ameliorates mitochondrial cristae remodeling, mitochondrial dysfunction, and neuronal apoptosis in prion diseases.
Wu W, Zhao D, Shah SZA, Zhang X, Lai M, Yang D, Wu X, Guan Z, Li J, Zhao H, Li W, Gao H, Zhou X, Qiao J, Yang L
Cell death & disease 2019 Sep 24;10(10):710
Cell death & disease 2019 Sep 24;10(10):710
Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae.
Yuan J, Chen C, Cui J, Lu J, Yan C, Wei X, Zhao X, Li N, Li S, Xue G, Cheng W, Li B, Li H, Lin W, Tian C, Zhao J, Han J, An D, Zhang Q, Wei H, Zheng M, Ma X, Li W, Chen X, Zhang Z, Zeng H, Ying S, Wu J, Yang R, Liu D
Cell metabolism 2019 Oct 1;30(4):675-688.e7
Cell metabolism 2019 Oct 1;30(4):675-688.e7
Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model.
Zhou Y, Carmona S, Muhammad AKMG, Bell S, Landeros J, Vazquez M, Ho R, Franco A, Lu B, Dorn GW 2nd, Wang S, Lutz CM, Baloh RH
The Journal of clinical investigation 2019 Mar 18;129(4):1756-1771
The Journal of clinical investigation 2019 Mar 18;129(4):1756-1771
Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.
Chung KP, Hsu CL, Fan LC, Huang Z, Bhatia D, Chen YJ, Hisata S, Cho SJ, Nakahira K, Imamura M, Choi ME, Yu CJ, Cloonan SM, Choi AMK
Nature communications 2019 Jul 29;10(1):3390
Nature communications 2019 Jul 29;10(1):3390
Arsenic-induced cardiotoxicity correlates with mitochondrial damage and trace elements imbalance in broiler chickens.
Li S, Zhao H, Wang Y, Shao Y, Liu J, Xing M
Poultry science 2019 Feb 1;98(2):734-744
Poultry science 2019 Feb 1;98(2):734-744
Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3-dependent mechanism in male mice.
Klimova N, Long A, Kristian T
Journal of neuroscience research 2019 Aug;97(8):975-990
Journal of neuroscience research 2019 Aug;97(8):975-990
CDDO-Me Selectively Attenuates CA1 Neuronal Death Induced by Status Epilepticus via Facilitating Mitochondrial Fission Independent of LONP1.
Kim JE, Park H, Choi SH, Kong MJ, Kang TC
Cells 2019 Aug 5;8(8)
Cells 2019 Aug 5;8(8)
Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson's disease.
Brahmachari S, Lee S, Kim S, Yuan C, Karuppagounder SS, Ge P, Shi R, Kim EJ, Liu A, Kim D, Quintin S, Jiang H, Kumar M, Yun SP, Kam TI, Mao X, Lee Y, Swing DA, Tessarollo L, Ko HS, Dawson VL, Dawson TM
Brain : a journal of neurology 2019 Aug 1;142(8):2380-2401
Brain : a journal of neurology 2019 Aug 1;142(8):2380-2401
Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells.
Zhong X, Cui P, Cai Y, Wang L, He X, Long P, Lu K, Yan R, Zhang Y, Pan X, Zhao X, Li W, Zhang H, Zhou Q, Gao P
Cell metabolism 2019 Apr 2;29(4):979-992.e4
Cell metabolism 2019 Apr 2;29(4):979-992.e4
UBIAD1 protects against oxygen-glucose deprivation/reperfusion-induced multiple subcellular organelles injury through PI3K/AKT pathway in N2A cells.
Huang Y, Hu Z
Journal of cellular physiology 2018 Sep;233(9):7480-7496
Journal of cellular physiology 2018 Sep;233(9):7480-7496
In Vivo Deletion of β-Cell Drp1 Impairs Insulin Secretion Without Affecting Islet Oxygen Consumption.
Hennings TG, Chopra DG, DeLeon ER, VanDeusen HR, Sesaki H, Merrins MJ, Ku GM
Endocrinology 2018 Sep 1;159(9):3245-3256
Endocrinology 2018 Sep 1;159(9):3245-3256
Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer's disease.
Reddy PH, Yin X, Manczak M, Kumar S, Pradeepkiran JA, Vijayan M, Reddy AP
Human molecular genetics 2018 Jul 15;27(14):2502-2516
Human molecular genetics 2018 Jul 15;27(14):2502-2516
Pro-Inflammatory CXCR3 Impairs Mitochondrial Function in Experimental Non-Alcoholic Steatohepatitis.
Du J, Zhang X, Han J, Man K, Zhang Y, Chu ES, Nan Y, Yu J
Theranostics 2017;7(17):4192-4203
Theranostics 2017;7(17):4192-4203
Exercise Combined with Rhodiola sacra Supplementation Improves Exercise Capacity and Ameliorates Exhaustive Exercise-Induced Muscle Damage through Enhancement of Mitochondrial Quality Control.
Dun Y, Liu S, Zhang W, Xie M, Qiu L
Oxidative medicine and cellular longevity 2017;2017:8024857
Oxidative medicine and cellular longevity 2017;2017:8024857
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
Wang L, Zhang T, Wang L, Cai Y, Zhong X, He X, Hu L, Tian S, Wu M, Hui L, Zhang H, Gao P
The EMBO journal 2017 May 15;36(10):1330-1347
The EMBO journal 2017 May 15;36(10):1330-1347
Low-level laser therapy for beta amyloid toxicity in rat hippocampus.
Lu Y, Wang R, Dong Y, Tucker D, Zhao N, Ahmed ME, Zhu L, Liu TC, Cohen RM, Zhang Q
Neurobiology of aging 2017 Jan;49:165-182
Neurobiology of aging 2017 Jan;49:165-182
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Li S, Zhao H, Wang Y, Shao Y, Li J, Liu J, Xing M
Chemosphere 2017 Dec;189:489-497
Chemosphere 2017 Dec;189:489-497
Antagonistic effects of selenium on cadmium-induced apoptosis by restoring the mitochondrial dynamic equilibrium and energy metabolism in chicken spleens.
Xu Z, Jin X, Pan T, Liu T, Wan N, Li S
Oncotarget 2017 Aug 8;8(32):52629-52641
Oncotarget 2017 Aug 8;8(32):52629-52641
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Sharoar MG, Shi Q, Ge Y, He W, Hu X, Perry G, Zhu X, Yan R
Molecular psychiatry 2016 Sep;21(9):1263-71
Molecular psychiatry 2016 Sep;21(9):1263-71
Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis.
Kim DI, Lee KH, Gabr AA, Choi GE, Kim JS, Ko SH, Han HJ
Biochimica et biophysica acta 2016 Nov;1863(11):2820-2834
Biochimica et biophysica acta 2016 Nov;1863(11):2820-2834
Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization.
Li H, Ruan Y, Zhang K, Jian F, Hu C, Miao L, Gong L, Sun L, Zhang X, Chen S, Chen H, Liu D, Song Z
Cell death and differentiation 2016 Mar;23(3):380-92
Cell death and differentiation 2016 Mar;23(3):380-92
Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology.
Zhang C, Shi Z, Zhang L, Zhou Z, Zheng X, Liu G, Bu G, Fraser PE, Xu H, Zhang YW
Journal of cell science 2016 Mar 1;129(5):994-1002
Journal of cell science 2016 Mar 1;129(5):994-1002
Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
Manczak M, Kandimalla R, Fry D, Sesaki H, Reddy PH
Human molecular genetics 2016 Dec 1;25(23):5148-5166
Human molecular genetics 2016 Dec 1;25(23):5148-5166
Porcine reproductive and respiratory syndrome virus triggers mitochondrial fission and mitophagy to attenuate apoptosis.
Li S, Wang J, Zhou A, Khan FA, Hu L, Zhang S
Oncotarget 2016 Aug 30;7(35):56002-56012
Oncotarget 2016 Aug 30;7(35):56002-56012
Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice.
Leduc-Gaudet JP, Picard M, St-Jean Pelletier F, Sgarioto N, Auger MJ, Vallée J, Robitaille R, St-Pierre DH, Gouspillou G
Oncotarget 2015 Jul 20;6(20):17923-37
Oncotarget 2015 Jul 20;6(20):17923-37
MARCH5-mediated quality control on acetylated Mfn1 facilitates mitochondrial homeostasis and cell survival.
Park YY, Nguyen OT, Kang H, Cho H
Cell death & disease 2014 Apr 10;5(4):e1172
Cell death & disease 2014 Apr 10;5(4):e1172
Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart.
Hoshino A, Mita Y, Okawa Y, Ariyoshi M, Iwai-Kanai E, Ueyama T, Ikeda K, Ogata T, Matoba S
Nature communications 2013;4:2308
Nature communications 2013;4:2308
Mitofusin 1 is degraded at G2/M phase through ubiquitylation by MARCH5.
Park YY, Cho H
Cell division 2012 Dec 20;7(1):25
Cell division 2012 Dec 20;7(1):25
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human kidney tissue were subjected to SDS PAGE followed by western blot with 13798-1-AP(MFN1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 13798-1-AP(MFN1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MFN1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MFN1. This antibody recognizes human,mouse,rat antigen. The MFN1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
