Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 10341-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10341-1-AP, RRID:AB_2289267
- Product name
- ACTL6A antibody
- Antibody type
- Polyclonal
- Description
- ACTL6A antibody (Cat. #10341-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The chromatin remodeling factor BAP18 promotes non-small cell lung cancer progression via the recruitment of β-catenin with the transcriptional coactivator complex ACTL6A-PAF1.
TGF-β and RAS jointly unmask primed enhancers to drive metastasis.
Circ_0084615 promotes epithelial-mesenchymal transition-mediated tumor progression in hepatocellular carcinoma.
Oxidative medicine and cellular longevity the role and mechanism of NCOA4 in ferroptosis induced by intestinal ischemia reperfusion.
Corilagin alleviated intestinal ischemia-reperfusion injury by modulating endoplasmic reticulum stress via bonding with Bip.
FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A.
LncRNA HAND2-AS1 promotes liver cancer stem cell self-renewal via BMP signaling.
A Diet-Sensitive BAF60a-Mediated Pathway Links Hepatic Bile Acid Metabolism to Cholesterol Absorption and Atherosclerosis.
Baf60c drives glycolytic metabolism in the muscle and improves systemic glucose homeostasis through Deptor-mediated Akt activation.
Genome-wide coactivation analysis of PGC-1alpha identifies BAF60a as a regulator of hepatic lipid metabolism.
Hao J, Hu Q, Li X, Shi S, Na F, Zeng K, Li H, Zhao Y, Zhao M
The Journal of biological chemistry 2025 Sep;301(9):110596
The Journal of biological chemistry 2025 Sep;301(9):110596
TGF-β and RAS jointly unmask primed enhancers to drive metastasis.
Lee JH, Sánchez-Rivera FJ, He L, Basnet H, Chen FX, Spina E, Li L, Torner C, Chan JE, Yarlagadda DVK, Park JS, Sussman C, Rudin CM, Lowe SW, Tammela T, Macias MJ, Koche RP, Massagué J
Cell 2024 Oct 31;187(22):6182-6199.e29
Cell 2024 Oct 31;187(22):6182-6199.e29
Circ_0084615 promotes epithelial-mesenchymal transition-mediated tumor progression in hepatocellular carcinoma.
Wu Y, Peng L
Annals of gastroenterological surgery 2024 Nov;8(6):1107-1117
Annals of gastroenterological surgery 2024 Nov;8(6):1107-1117
Oxidative medicine and cellular longevity the role and mechanism of NCOA4 in ferroptosis induced by intestinal ischemia reperfusion.
Li K, Wang A, Diao Y, Fan S
International immunopharmacology 2024 May 30;133:112155
International immunopharmacology 2024 May 30;133:112155
Corilagin alleviated intestinal ischemia-reperfusion injury by modulating endoplasmic reticulum stress via bonding with Bip.
Wang Y, Liu G, Qiu F, Li X, Diao Y, Yang M, Yang S, Li B, Han Q, Liu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156011
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156011
FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A.
Wang X, Li Y, Li Y, Liu P, Liu S, Pan Y
Stem cells international 2022;2022:3242482
Stem cells international 2022;2022:3242482
LncRNA HAND2-AS1 promotes liver cancer stem cell self-renewal via BMP signaling.
Wang Y, Zhu P, Luo J, Wang J, Liu Z, Wu W, Du Y, Ye B, Wang D, He L, Ren W, Wang J, Sun X, Chen R, Tian Y, Fan Z
The EMBO journal 2019 Sep 2;38(17):e101110
The EMBO journal 2019 Sep 2;38(17):e101110
A Diet-Sensitive BAF60a-Mediated Pathway Links Hepatic Bile Acid Metabolism to Cholesterol Absorption and Atherosclerosis.
Meng ZX, Wang L, Chang L, Sun J, Bao J, Li Y, Chen YE, Lin JD
Cell reports 2015 Nov 24;13(8):1658-69
Cell reports 2015 Nov 24;13(8):1658-69
Baf60c drives glycolytic metabolism in the muscle and improves systemic glucose homeostasis through Deptor-mediated Akt activation.
Meng ZX, Li S, Wang L, Ko HJ, Lee Y, Jung DY, Okutsu M, Yan Z, Kim JK, Lin JD
Nature medicine 2013 May;19(5):640-5
Nature medicine 2013 May;19(5):640-5
Genome-wide coactivation analysis of PGC-1alpha identifies BAF60a as a regulator of hepatic lipid metabolism.
Li S, Liu C, Li N, Hao T, Han T, Hill DE, Vidal M, Lin JD
Cell metabolism 2008 Aug;8(2):105-17
Cell metabolism 2008 Aug;8(2):105-17
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 10341-1-AP(ACTL6A antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human ovary using 10341-1-AP(ACTL6A antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The ACTL6A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ACTL6A. This antibody recognizes human, mouse, rat antigen. The ACTL6A antibody has been validated for the following applications: ELISA, WB, IHC analysis.