NBP2-49133

antibody from Novus Biologicals

Targeting: PYCARD ASC, CARD5, TMS-1

Antibody data

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Validation data

Product number: NBP2-49133 - Provider product page
Provider: Novus Biologicals
Product name: Rabbit Polyclonal ASC/TMS1 Antibody
Antibody type: Polyclonal
Description: Immunogen affinity purified. Specificity of human ASC/TMS1 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
Reactivity: Human
Host: Rabbit
Isotype: IgG
Vial size: 0.1 ml
Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

PYCARD protein structure - NBP2-49133 shown in red.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: ASC/TMS1 Antibody [NBP2-49133] - Staining of human skeletal muscle shows low expression as expected.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: ASC/TMS1 Antibody [NBP2-49133] - Staining of human spleen shows high expression.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: ASC/TMS1 Antibody [NBP2-49133] - Staining in human spleen and skeletal muscle tissues using anti-PYCARD antibody. Corresponding PYCARD RNA-seq data are presented for the same tissues.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: ASC/TMS1 Antibody [NBP2-49133] - Staining of human cerebral cortex.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: ASC/TMS1 Antibody [NBP2-49133] - Staining of human lymph node.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: ASC/TMS1 Antibody [NBP2-49133] - Staining of human liver.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: ASC/TMS1 Antibody [NBP2-49133] - Analysis in human spleen and skeletal muscle tissues. Corresponding PYCARD RNA-seq data are presented for the same tissues.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: ASC/TMS1 Antibody [NBP2-49133] - Staining of human spleen shows strong cytoplasmic positivity in cells in red pulp.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: ASC/TMS1 Antibody [NBP2-49133] - Staining of human liver, lung, skeletal muscle and spleen using Anti-PYCARD antibody NBP2-49133 (A) shows similar protein distribution across tissues to independent antibody NBP2-48925 (B).

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: ASC/TMS1 Antibody [NBP2-49133] - Staining of human skeletal muscle shows low positivity in myocytes as expected.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: ASC/TMS1 Antibody [NBP2-49133] - Staining of human liver shows moderate cytoplasmic positivity in Kupffer cells.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: ASC/TMS1 Antibody [NBP2-49133] - Staining of human lymphoid tissues shows moderate cytoplasmic positivity in non-germinal center cells.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: ASC/TMS1 Antibody [NBP2-49133] - Staining of human lung shows moderate cytoplasmic positivity in macrophages.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: ASC/TMS1 Antibody [NBP2-49133] - Staining of human liver, lung, skeletal muscle and spleen using Anti-ASC/TMS1 antibody NBP2-49133 (A) shows similar protein distribution across tissues to independent antibody NBP2-48925 (B).