Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- ABIN499343 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-PYD and CARD Domain Containing (PYCARD) antibody
- Antibody type
- Polyclonal
- Antigen
- Human ASC Peptide (AP30084°CP-N)
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C.
Submitted references Rap1A and rap1B ras-family proteins are prominently expressed in the nucleus of squamous carcinomas: nuclear translocation of GTP-bound active form.
Murine ortholog of ASC, a CARD-containing protein, self-associates and exhibits restricted distribution in developing mouse embryos.
Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain protein TMS1.
TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers.
ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells.
Mitra RS, Zhang Z, Henson BS, Kurnit DM, Carey TE, D'Silva NJ
Oncogene 2003 Sep 18;22(40):6243-56
Oncogene 2003 Sep 18;22(40):6243-56
Murine ortholog of ASC, a CARD-containing protein, self-associates and exhibits restricted distribution in developing mouse embryos.
Masumoto J, Taniguchi S, Nakayama K, Ayukawa K, Sagara J
Experimental cell research 2001 Jan 15;262(2):128-33
Experimental cell research 2001 Jan 15;262(2):128-33
Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain protein TMS1.
McConnell BB, Vertino PM
Cancer research 2000 Nov 15;60(22):6243-7
Cancer research 2000 Nov 15;60(22):6243-7
TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers.
Conway KE, McConnell BB, Bowring CE, Donald CD, Warren ST, Vertino PM
Cancer research 2000 Nov 15;60(22):6236-42
Cancer research 2000 Nov 15;60(22):6236-42
ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells.
Masumoto J, Taniguchi S, Ayukawa K, Sarvotham H, Kishino T, Niikawa N, Hidaka E, Katsuyama T, Higuchi T, Sagara J
The Journal of biological chemistry 1999 Nov 26;274(48):33835-8
The Journal of biological chemistry 1999 Nov 26;274(48):33835-8
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of ASC in HL60 whole cell lysate in the absence (A) or presence (B) of blocking peptide with AP30084PU-N ASC antibody at 1 ?g /ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of ASC in HL60 cells with AP30084PU-N ASC antibody at 5 ?g/ml.