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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [8]
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- Product number
- ABIN1169071 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-PYD and CARD Domain Containing (PYCARD) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide corresponding to aa at the N-terminal human Asc.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Vial size
- 100 µg
- Concentration
- 1mg/ml
- Storage
- Short Term: +4°C. Long Term: -20°C
Submitted references Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis.
Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation.
Localization and functionality of the inflammasome in neutrophils.
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines.
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction.
Inflammatory role of ASC in antigen-induced arthritis is independent of caspase-1, NALP-3, and IPAF.
P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage.
Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sánchez M, Escames G
Journal of pineal research 2015 Jan;58(1):34-49
Journal of pineal research 2015 Jan;58(1):34-49
Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation.
Dowling JK, Becker CE, Bourke NM, Corr SC, Connolly DJ, Quinn SR, Pandolfi PP, Mansell A, O'Neill LA
The Journal of biological chemistry 2014 Mar 7;289(10):6429-37
The Journal of biological chemistry 2014 Mar 7;289(10):6429-37
Localization and functionality of the inflammasome in neutrophils.
Bakele M, Joos M, Burdi S, Allgaier N, Pöschel S, Fehrenbacher B, Schaller M, Marcos V, Kümmerle-Deschner J, Rieber N, Borregaard N, Yazdi A, Hector A, Hartl D
The Journal of biological chemistry 2014 Feb 21;289(8):5320-9
The Journal of biological chemistry 2014 Feb 21;289(8):5320-9
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Heneka MT, Kummer MP, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng TC, Gelpi E, Halle A, Korte M, Latz E, Golenbock DT
Nature 2013 Jan 31;493(7434):674-8
Nature 2013 Jan 31;493(7434):674-8
Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines.
Dashdorj A, Jyothi KR, Lim S, Jo A, Nguyen MN, Ha J, Yoon KS, Kim HJ, Park JH, Murphy MP, Kim SS
BMC medicine 2013 Aug 6;11:178
BMC medicine 2013 Aug 6;11:178
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction.
Shi CS, Shenderov K, Huang NN, Kabat J, Abu-Asab M, Fitzgerald KA, Sher A, Kehrl JH
Nature immunology 2012 Jan 29;13(3):255-63
Nature immunology 2012 Jan 29;13(3):255-63
Inflammatory role of ASC in antigen-induced arthritis is independent of caspase-1, NALP-3, and IPAF.
Kolly L, Karababa M, Joosten LA, Narayan S, Salvi R, Pétrilli V, Tschopp J, van den Berg WB, So AK, Busso N
Journal of immunology (Baltimore, Md. : 1950) 2009 Sep 15;183(6):4003-12
Journal of immunology (Baltimore, Md. : 1950) 2009 Sep 15;183(6):4003-12
P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage.
Pelegrin P, Barroso-Gutierrez C, Surprenant A
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7147-57
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7147-57
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