CABT-L3217

antibody from Creative Diagnostics

Targeting: FAP DPPIV

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

CABT-L3217

Provider

Creative Diagnostics

Product name

Mouse Anti-Mouse Fibroblast Activation Protein monoclonal antibody, clone 84.4

Antibody type

Monoclonal

Description

Fibroblast activation protein (FAP), also known as seprase, is a cell surface, type II integral transmembrane serine protease encoded by the Fap gene. It displays in vitro gelatinase, endopeptidase, and potentially collagenase activity. FAP has been detected on pericytes, bone marrow-derived mesenchymal stem cells, and a small population of macrophages. FAP is highly expressed on mesenchymal cells during embryogenesis and is repressed shortly after birth. FAP expression is up-regulated on activated fibroblasts in conditions associated with matrix remodeling, such as sites of inflammation in disease including wound healing, fibrosis, rheumatoid arthritis and osteoarthritis, liver disease, inflammatory bowel diseases, and several types of cancer.

Reactivity

Mouse

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

84.4

Vial size

100 ug

Storage

Long time storage is recommended at -20°C.