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LearnBS3562
antibody from Bioworld Technology, Inc
Targeting: SCN2A
HBSCI, HBSCII, Nav1.2, SCN2A1, SCN2A2
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS3562 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS3562, RRID:AB_1661990
- Product name
- Na+ CP type IIÏ« (K1032) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 1002-1052 of Human Na+ CP type IIÏ«.
- Description
- Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarize the cell. The Ï« subunits of sodium channels type I and III are predominantly expressed in neuronal cell bodies and proximal processes, while type IIÏ« subunits are more abundant along axons. The ÉÇ1 subunit of sodium channel type I is expressed in brain, skeletal and cardiac muscle. In the brain, ÉÇ1 and ÉÇ2 are highly expressed in Purkinje cells, and ÉÇ1 is also expressed in the pyramidal cells of the deep cerebellar nuclei. Impaired voltage-gated sodium channels lead to a number of diseases including myotonia.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of Na+ CP type II¦Á (K1032) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Raw264.7 whole cell lysateLane3:H9C2 whole cell lysate
