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- References [22]
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- Product number
- 12632-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12632-1-AP, RRID:AB_2076629
- Product name
- LAMP3 antibody
- Antibody type
- Polyclonal
- Description
- LAMP3 antibody (Cat. #12632-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Amplified Type I Interferon Response in Sjögren's Disease via Ectopic Toll-Like Receptor 7 Expression in Salivary Gland Epithelial Cells Induced by Lysosome-Associated Membrane Protein 3.
A pan-cancer analysis of prognostic significance and immunological role of lysosomal-associated membrane protein 3.
The HN protein of Newcastle disease virus induces cell apoptosis through the induction of lysosomal membrane permeabilization.
Inhibition of LAMP3 mediates the protective effect of vitamin D against hypoxia/reoxygenation in trophoblast cells.
Lysosome-Associated Membrane Protein 3 Induces Lysosome-Dependent Cell Death by Impairing Autophagic Caspase 8 Degradation in the Salivary Glands of Individuals With Sjögren's Disease.
LAMP3 transfer via extracellular particles induces apoptosis in Sjögren's disease.
Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients.
Correction of LAMP3-associated salivary gland hypofunction by aquaporin gene therapy.
Lysosomal exocytosis of HSP70 stimulates monocytic BMP6 expression in Sjögren's syndrome.
LAMP3 inhibits autophagy and contributes to cell death by lysosomal membrane permeabilization.
Upregulation of ATF4-LAMP3 Axis by ORF45 Facilitates Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus.
Differences in the Immune Response of the Nonmetastatic Axillary Lymph Nodes between Triple-Negative and Luminal A Breast Cancer Surrogate Subtypes.
Intrapulmonary distal airway stem cell transplantation repairs lung injury in chronic obstructive pulmonary disease.
Peritumoral immune infiltrates in primary tumours are not associated with the presence of axillary lymph node metastasis in breast cancer: a retrospective cohort study.
The Immune Response in Nonmetastatic Axillary Lymph Nodes Is Associated with the Presence of Axillary Metastasis and Breast Cancer Patient Outcome.
Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway.
Alveolar Differentiation Potency of Human Distal Airway Stem Cells Is Associated with Pulmonary Pathological Conditions.
Regeneration of functional alveoli by adult human SOX9(+) airway basal cell transplantation.
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.
Autophagy activation is required for influenza A virus-induced apoptosis and replication.
Suppression of influenza A virus replication in human lung epithelial cells by noncytotoxic concentrations bafilomycin A1.
Diminished parkin solubility and co-localization with intraneuronal amyloid-β are associated with autophagic defects in Alzheimer's disease.
Nakamura H, Tanaka T, Zheng C, Afione SA, Atsumi T, Noguchi M, Oliveira FR, Motta ACF, Chahud F, Rocha EM, Warner BM, Chiorini JA
Arthritis & rheumatology (Hoboken, N.J.) 2024 Jul;76(7):1109-1119
Arthritis & rheumatology (Hoboken, N.J.) 2024 Jul;76(7):1109-1119
A pan-cancer analysis of prognostic significance and immunological role of lysosomal-associated membrane protein 3.
Feng X, Gao L, Shen X, Li M, Wang X, Hao Y, Chen J, Zhai Y, Zou B, Yao S, Guo Y, Zhang L
Journal of cellular and molecular medicine 2024 Feb;28(3):e18088
Journal of cellular and molecular medicine 2024 Feb;28(3):e18088
The HN protein of Newcastle disease virus induces cell apoptosis through the induction of lysosomal membrane permeabilization.
Chen Y, Zhu S, Liao T, Wang C, Han J, Yang Z, Lu X, Hu Z, Hu J, Wang X, Gu M, Gao R, Liu K, Liu X, Ding C, Hu S, Liu X
PLoS pathogens 2024 Feb;20(2):e1011981
PLoS pathogens 2024 Feb;20(2):e1011981
Inhibition of LAMP3 mediates the protective effect of vitamin D against hypoxia/reoxygenation in trophoblast cells.
Tian X, Zheng L, Ma J, Xu Y, Zhang Y, Pi Y
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2023;56:e12816
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2023;56:e12816
Lysosome-Associated Membrane Protein 3 Induces Lysosome-Dependent Cell Death by Impairing Autophagic Caspase 8 Degradation in the Salivary Glands of Individuals With Sjögren's Disease.
Nakamura H, Tanaka T, Zheng C, Afione SA, Warner BM, Noguchi M, Atsumi T, Chiorini JA
Arthritis & rheumatology (Hoboken, N.J.) 2023 Sep;75(9):1586-1598
Arthritis & rheumatology (Hoboken, N.J.) 2023 Sep;75(9):1586-1598
LAMP3 transfer via extracellular particles induces apoptosis in Sjögren's disease.
Tanaka T, Nakamura H, Tran DT, Warner BM, Wang Y, Atsumi T, Noguchi M, Chiorini JA
Scientific reports 2023 Feb 14;13(1):2595
Scientific reports 2023 Feb 14;13(1):2595
Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients.
Zhang Z, Ji W, Huang J, Zhang Y, Zhou Y, Zhang J, Dong Y, Yuan T, Yang Q, Ding X, Tang L, Li H, Yin J, Wang Y, Ji T, Fei J, Zhang B, Chen P, Hu H
Clinical and translational medicine 2022 Nov;12(11):e1072
Clinical and translational medicine 2022 Nov;12(11):e1072
Correction of LAMP3-associated salivary gland hypofunction by aquaporin gene therapy.
Nakamura H, Tanaka T, Zheng C, Afione SA, Warner BM, Noguchi M, Atsumi T, Chiorini JA
Scientific reports 2022 Nov 3;12(1):18570
Scientific reports 2022 Nov 3;12(1):18570
Lysosomal exocytosis of HSP70 stimulates monocytic BMP6 expression in Sjögren's syndrome.
Mo YQ, Nakamura H, Tanaka T, Odani T, Perez P, Ji Y, French BN, Pranzatelli TJ, Michael DG, Yin H, Chow SS, Khalaj M, Afione SA, Zheng C, Oliveira FR, Motta ACF, Ribeiro-Silva A, Rocha EM, Nguyen CQ, Noguchi M, Atsumi T, Warner BM, Chiorini JA
The Journal of clinical investigation 2022 Mar 15;132(6)
The Journal of clinical investigation 2022 Mar 15;132(6)
LAMP3 inhibits autophagy and contributes to cell death by lysosomal membrane permeabilization.
Tanaka T, Warner BM, Michael DG, Nakamura H, Odani T, Yin H, Atsumi T, Noguchi M, Chiorini JA
Autophagy 2022 Jul;18(7):1629-1647
Autophagy 2022 Jul;18(7):1629-1647
Upregulation of ATF4-LAMP3 Axis by ORF45 Facilitates Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus.
Sun Q, Wang F, Chen Q, Sarid R, Li X, Kuang E
Journal of virology 2022 Dec 14;96(23):e0145622
Journal of virology 2022 Dec 14;96(23):e0145622
Differences in the Immune Response of the Nonmetastatic Axillary Lymph Nodes between Triple-Negative and Luminal A Breast Cancer Surrogate Subtypes.
López C, Gibert-Ramos A, Bosch R, Korzynska A, García-Rojo M, Bueno G, García-Fontgivell JF, Martínez González S, Fontoura L, Gras Navarro A, Sauras Colón E, Casanova Ribes J, Roszkowiak L, Roso A, Berenguer M, Llobera M, Baucells J, Lejeune M
The American journal of pathology 2021 Mar;191(3):545-554
The American journal of pathology 2021 Mar;191(3):545-554
Intrapulmonary distal airway stem cell transplantation repairs lung injury in chronic obstructive pulmonary disease.
Wang X, Zhao Y, Li D, Feng Y, Xie Y, Zhou Y, Zhou M, Wang Y, Qu J, Zuo W
Cell proliferation 2021 Jun;54(6):e13046
Cell proliferation 2021 Jun;54(6):e13046
Peritumoral immune infiltrates in primary tumours are not associated with the presence of axillary lymph node metastasis in breast cancer: a retrospective cohort study.
López C, Bosch-Príncep R, Orero G, Fontoura Balagueró L, Korzynska A, García-Rojo M, Bueno G, Fernández-Carrobles MDM, Roszkowiak L, Callau Casanova C, Salvadó-Usach MT, Jaén Martínez J, Gibert-Ramos A, Roso-Llorach A, Gras Navarro A, Berenguer-Poblet M, Llobera M, Gil Garcia J, Tomás B, Gestí V, Laine E, Plancoulaine B, Baucells J, Lejeune M
PeerJ 2020;8:e9779
PeerJ 2020;8:e9779
The Immune Response in Nonmetastatic Axillary Lymph Nodes Is Associated with the Presence of Axillary Metastasis and Breast Cancer Patient Outcome.
López C, Bosch R, Orero G, Korzynska A, García-Rojo M, Bueno G, Fernández-Carrobles MDM, Gibert-Ramos A, Roszkowiak L, Callau C, Fontoura L, Salvadó MT, Álvaro T, Jaén J, Roso-Llorach A, Llobera M, Gil J, Onyos M, Plancoulaine B, Baucells J, Lejeune M
The American journal of pathology 2020 Mar;190(3):660-673
The American journal of pathology 2020 Mar;190(3):660-673
Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway.
Sun X, Zhou Y, Zhang R, Wang Z, Xu M, Zhang D, Huang J, Luo F, Li F, Ni Z, Zhou S, Chen H, Chen S, Chen L, Du X, Chen B, Huang H, Liu P, Yin L, Qiu J, Chen D, Deng C, Xie Y, Luo L, Chen L
Nature communications 2020 Jan 24;11(1):479
Nature communications 2020 Jan 24;11(1):479
Alveolar Differentiation Potency of Human Distal Airway Stem Cells Is Associated with Pulmonary Pathological Conditions.
Wang Y, Lu Y, Wu Y, Sun Y, Zhou Y, Ma Q, Zheng Y, Yu Q, Cao Y, Chen G, Zhang T, Dai X, Ren T, Ma Y, Zuo W
Stem cells international 2019;2019:7123078
Stem cells international 2019;2019:7123078
Regeneration of functional alveoli by adult human SOX9(+) airway basal cell transplantation.
Ma Q, Ma Y, Dai X, Ren T, Fu Y, Liu W, Han Y, Wu Y, Cheng Y, Zhang T, Zuo W
Protein & cell 2018 Mar;9(3):267-282
Protein & cell 2018 Mar;9(3):267-282
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.
Shi Y, Lin S, Staats KA, Li Y, Chang WH, Hung ST, Hendricks E, Linares GR, Wang Y, Son EY, Wen X, Kisler K, Wilkinson B, Menendez L, Sugawara T, Woolwine P, Huang M, Cowan MJ, Ge B, Koutsodendris N, Sandor KP, Komberg J, Vangoor VR, Senthilkumar K, Hennes V, Seah C, Nelson AR, Cheng TY, Lee SJ, August PR, Chen JA, Wisniewski N, Hanson-Smith V, Belgard TG, Zhang A, Coba M, Grunseich C, Ward ME, van den Berg LH, Pasterkamp RJ, Trotti D, Zlokovic BV, Ichida JK
Nature medicine 2018 Mar;24(3):313-325
Nature medicine 2018 Mar;24(3):313-325
Autophagy activation is required for influenza A virus-induced apoptosis and replication.
Yeganeh B, Ghavami S, Rahim MN, Klonisch T, Halayko AJ, Coombs KM
Biochimica et biophysica acta. Molecular cell research 2018 Feb;1865(2):364-378
Biochimica et biophysica acta. Molecular cell research 2018 Feb;1865(2):364-378
Suppression of influenza A virus replication in human lung epithelial cells by noncytotoxic concentrations bafilomycin A1.
Yeganeh B, Ghavami S, Kroeker AL, Mahood TH, Stelmack GL, Klonisch T, Coombs KM, Halayko AJ
American journal of physiology. Lung cellular and molecular physiology 2015 Feb 1;308(3):L270-86
American journal of physiology. Lung cellular and molecular physiology 2015 Feb 1;308(3):L270-86
Diminished parkin solubility and co-localization with intraneuronal amyloid-β are associated with autophagic defects in Alzheimer's disease.
Lonskaya I, Shekoyan AR, Hebron ML, Desforges N, Algarzae NK, Moussa CE
Journal of Alzheimer's disease : JAD 2013;33(1):231-47
Journal of Alzheimer's disease : JAD 2013;33(1):231-47
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 12632-1-AP(LAMP3 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung using 12632-1-AP(LAMP3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LAMP3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human LAMP3. This antibody recognizes human, mouse, rat antigen. The LAMP3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
