10658-3-AP

antibody from Proteintech Group

Targeting: AHCYL1 IRBIT, PPP1R78, XPVKONA

Provider product page for 10658-3-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [20]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]

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Product number: 10658-3-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#10658-3-AP, RRID:AB_2226013
Product name: AHCYL1 antibody
Antibody type: Polyclonal
Description: KD/KO validated AHCYL1 antibody (Cat. #10658-3-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

AHCYL1 protein structure - 10658-3-AP shown in red.

Submitted references Quantitative reactive cysteinome profiling reveals a functional link between ferroptosis and proteasome-mediated degradation.

Wang Y, Wang C
Cell death and differentiation 2023 Jan;30(1):125-136

In ovo injection of betaine promotes adrenal steroidogenesis in pre-hatched chicken fetuses.

Abobaker H, Omer NA, Hu Y, Idriss AA, Zhao R
Poultry science 2022 Jun;101(6):101871

Grandmaternal betaine supplementation enhances hepatic IGF2 expression in F2 rat offspring through modification of promoter DNA methylation.

Yang S, Zhao N, Sun B, Yang Y, Hu Y, Zhao R
Journal of the science of food and agriculture 2020 Mar 15;100(4):1486-1494

Maternal betaine supplementation decreases hepatic cholesterol deposition in chicken offspring with epigenetic modulation of SREBP2 and CYP7A1 genes.

Hu Y, Feng Y, Ding Z, Lv L, Sui Y, Sun Q, Abobaker H, Cai D, Zhao R
Poultry science 2020 Jun;99(6):3111-3120

A New Therapeutic Strategy Targeting Protein Deacetylation for Spinal Cord Injury.

Liu X, Ma B, Zhang H, Chai R, Xiang L
Neuroscience 2020 Dec 15;451:197-206

Protective Role of IRBIT on Sodium Bicarbonate Cotransporter-n1 for Migratory Cancer Cells.

Hwang S, Shin DM, Hong JH
Pharmaceutics 2020 Aug 27;12(9)

Transgenerational Inheritance of Betaine-Induced Epigenetic Alterations in Estrogen-Responsive IGF-2/IGFBP2 Genes in Rat Hippocampus.

Yang Y, Jiang W, Yang S, Qi F, Zhao R
Molecular nutrition & food research 2020 Apr;64(8):e1900823

DNA Hypomethylation of GR Promoters is Associated with GR Activation and BDNF/AKT/ERK1/2-Induced Hippocampal Neurogenesis in Mice Derived From Folic-Acid-Supplemented Dams.

Yang Y, Yang S, Liu J, Feng Y, Qi F, Zhao R
Molecular nutrition & food research 2019 Jun;63(12):e1801334

Low IRBIT Levels Are Associated With Chemo-resistance in Gastric Cancer Patients.

Nakazawa N, Ogata K, Yokobori T, Ide M, Baatar S, Ubukata Y, Kimura A, Kogure N, Sohda M, Kuwano H, Saeki H, Shirabe K
Anticancer research 2019 Aug;39(8):4111-4116

Mitotically Stable Modification of DNA Methylation in IGF2/H19 Imprinting Control Region Is Associated with Activated Hepatic IGF2 Expression in Offspring Rats from Betaine-Supplemented Dams.

Yang S, Zhao N, Yang Y, Hu Y, Dong H, Zhao R
Journal of agricultural and food chemistry 2018 Mar 21;66(11):2704-2713

Corticosterone-Induced Lipogenesis Activation and Lipophagy Inhibition in Chicken Liver Are Alleviated by Maternal Betaine Supplementation.

Hu Y, Sun Q, Hu Y, Hou Z, Zong Y, Omer NA, Abobaker H, Zhao R
The Journal of nutrition 2018 Mar 1;148(3):316-325

Maternal betaine administration modulates hepatic type 1 iodothyronine deiodinase (Dio1) expression in chicken offspring through epigenetic modifications.

Hou Z, Sun Q, Hu Y, Yang S, Zong Y, Zhao R
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2018 Apr;218:30-36

Maternal betaine supplementation in rats induces intergenerational changes in hepatic IGF-1 expression and DNA methylation.

Zhao N, Yang S, Hu Y, Dong H, Zhao R
Molecular nutrition & food research 2017 Aug;61(8)

Folate deprivation induces cell cycle arrest at G0/G1 phase and apoptosis in hippocampal neuron cells through down-regulation of IGF-1 signaling pathway.

Yang Y, Li X, Sun Q, He B, Jia Y, Cai D, Zhao R
The international journal of biochemistry & cell biology 2016 Oct;79:222-230

Maternal Betaine Supplementation throughout Gestation and Lactation Modifies Hepatic Cholesterol Metabolic Genes in Weaning Piglets via AMPK/LXR-Mediated Pathway and Histone Modification.

Cai D, Yuan M, Liu H, Pan S, Ma W, Hong J, Zhao R
Nutrients 2016 Oct 18;8(10)

Downregulation of miR-150 Expression by DNA Hypermethylation Is Associated with High 2-Hydroxy-(4-methylthio)butanoic Acid-Induced Hepatic Cholesterol Accumulation in Nursery Piglets.

Jia Y, Ling M, Zhang L, Jiang S, Sha Y, Zhao R
Journal of agricultural and food chemistry 2016 Oct 12;64(40):7530-7539

In Ovo injection of betaine affects hepatic cholesterol metabolism through epigenetic gene regulation in newly hatched chicks.

Hu Y, Sun Q, Li X, Wang M, Cai D, Li X, Zhao R
PloS one 2015;10(4):e0122643

Dietary betaine supplementation to gestational sows enhances hippocampal IGF2 expression in newborn piglets with modified DNA methylation of the differentially methylated regions.

Li X, Sun Q, Li X, Cai D, Sui S, Jia Y, Song H, Zhao R
European journal of nutrition 2015 Oct;54(7):1201-10

Maternal Betaine Supplementation during Gestation Enhances Expression of mtDNA-Encoded Genes through D-Loop DNA Hypomethylation in the Skeletal Muscle of Newborn Piglets.

Jia Y, Song H, Gao G, Cai D, Yang X, Zhao R
Journal of agricultural and food chemistry 2015 Nov 25;63(46):10152-60

Betaine supplementation in maternal diet modulates the epigenetic regulation of hepatic gluconeogenic genes in neonatal piglets.

Cai D, Jia Y, Song H, Sui S, Lu J, Jiang Z, Zhao R
PloS one 2014;9(8):e105504

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Jurkat cells were subjected to SDS PAGE followed by western blot with 10658-3-AP(AHCYL1 antibody) at dilution of 1:1000
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunofluorescent analysis of Hela cells, using AHCYL1 antibody 10658-3-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Sample type: cell line