Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 14079-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- Kv1.3 antibody
- Antibody type
- Polyclonal
- Description
- Kv1.3 antibody (Cat. #14079-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Wuji Wan ameliorates ulcerative colitis by restoring impaired membrane transport.
Kv1.3 regulates macrophage immune function through PI3K/AKT signaling pathway to alleviate metabolic dysfunction-associated steatohepatitis.
Discovery of therapeutic promising natural products to target Kv1.3 channel, a transmembrane protein regulating immune disorders, through multidimensional virtual screening, molecular dynamics simulations and biological validation.
Kv1.3 expression on CD4 (+) T cells promotes interleukin-17A-associated airway inflammation and airway remodeling in asthma.
Therapeutic potential of voltage-dependent potassium channel subtype 1.3 blockade in alleviating macrophage-related renal inflammation and fibrogenesis.
Processed Buthus martensii Karsch scorpions ameliorate diet-induced NASH in mice by attenuating Kv1.3-mediated macrophage activation.
Clarithromycin attenuates airway epithelial-mesenchymal transition in ovalbumin-induced asthmatic mice through modulation of Kv1.3 channels and PI3K/Akt signaling.
The Kv1.3 ion channel acts as a host factor restricting viral entry.
NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology.
Inhibition of 15-lipoxygenase (15-LOX) reverses hypoxia-induced down-regulation of potassium channels Kv1.5 and Kv2.1Inhibition of 15-lipoxygenase (15-LOX) reverses hypoxia-induced down-regulation of potassium channels Kv1.5 and Kv2.1.
Zhang J, Zhang Y, Guo Y, Sun Y, Li Y, Li Q, Chen Y, Wang Y, Yang Q, Zhang M, Weng X, Deng Z
Frontiers in pharmacology 2026;17:1718919
Frontiers in pharmacology 2026;17:1718919
Kv1.3 regulates macrophage immune function through PI3K/AKT signaling pathway to alleviate metabolic dysfunction-associated steatohepatitis.
Ke T, Zhen WJ, Chen XX, Wang H, Chen S, Tian YY, Wang YT, Zhang L, Wu BM
Journal of molecular medicine (Berlin, Germany) 2026 Apr 11;104(1)
Journal of molecular medicine (Berlin, Germany) 2026 Apr 11;104(1)
Discovery of therapeutic promising natural products to target Kv1.3 channel, a transmembrane protein regulating immune disorders, through multidimensional virtual screening, molecular dynamics simulations and biological validation.
Zhang S, Chen N, Wu F, Xu X, Zheng X, Cheng Z, Wang M, Wu Y, Jiang S, Liu Q, Liu C, Zhang F, Han B
International journal of biological macromolecules 2025 May;308(Pt 2):142636
International journal of biological macromolecules 2025 May;308(Pt 2):142636
Kv1.3 expression on CD4 (+) T cells promotes interleukin-17A-associated airway inflammation and airway remodeling in asthma.
Sun B, Lin J
Translational research : the journal of laboratory and clinical medicine 2025 May;279:40-54
Translational research : the journal of laboratory and clinical medicine 2025 May;279:40-54
Therapeutic potential of voltage-dependent potassium channel subtype 1.3 blockade in alleviating macrophage-related renal inflammation and fibrogenesis.
Li SS, Liang Y, Kong JW, Zhang Q, Qian JR, Yu LX, Liu QF
Cell death discovery 2025 May 5;11(1):218
Cell death discovery 2025 May 5;11(1):218
Processed Buthus martensii Karsch scorpions ameliorate diet-induced NASH in mice by attenuating Kv1.3-mediated macrophage activation.
Xu E, Sang M, Xu W, Chen Y, Wang Z, Zhang Y, Lu W, Cao P
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118794
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118794
Clarithromycin attenuates airway epithelial-mesenchymal transition in ovalbumin-induced asthmatic mice through modulation of Kv1.3 channels and PI3K/Akt signaling.
Sun B, Shen K, Zhao R, Li Y, Lin J
International immunopharmacology 2024 Sep 30;139:112624
International immunopharmacology 2024 Sep 30;139:112624
The Kv1.3 ion channel acts as a host factor restricting viral entry.
Lang Y, Li F, Liu Q, Xia Z, Ji Z, Hu J, Cheng Y, Gao M, Sun F, Shen B, Xie C, Yi W, Wu Y, Yao J, Cao Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e20995
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e20995
NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology.
He X, Yang W, Zeng Z, Wei Y, Gao J, Zhang B, Li L, Liu L, Wan Y, Zeng Q, Gong Z, Liu L, Zhang H, Li Y, Yang S, Hu T, Wu L, Masliah E, Huang S, Cao H
Cellular & molecular immunology 2020 Mar;17(3):283-299
Cellular & molecular immunology 2020 Mar;17(3):283-299
Inhibition of 15-lipoxygenase (15-LOX) reverses hypoxia-induced down-regulation of potassium channels Kv1.5 and Kv2.1Inhibition of 15-lipoxygenase (15-LOX) reverses hypoxia-induced down-regulation of potassium channels Kv1.5 and Kv2.1.
Liu W, Wang D, Song K, Chen L, Zhu Y, Liu P, Zhu Y
International journal of clinical and experimental medicine 2014;7(11):4147-53
International journal of clinical and experimental medicine 2014;7(11):4147-53
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The Kv1.3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Kv1.3. This antibody recognizes human, mouse antigen. The Kv1.3 antibody has been validated for the following applications: ELISA, WB analysis.