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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [266]
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- Product number
- 27733-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#27733-1-AP, RRID:AB_2810292
- Product name
- OPA1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated OPA1 antibody (Cat. #27733-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, rat, mouse and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Arsenic trioxide-induced acute kidney injury: OPA1- and Drp1-mediated mitochondrial dynamics imbalance, PINK1/Parkin-dependent mitophagy, and Chuanhuang Fang III.
The purinergic receptor P2rx7 mediated ATP sensing is required to prevent bone aging by directing mitochondrial fitness of MSCs.
Rejuvenation of THY1(+) nucleus pulposus-derived stem cells promotes intervertebral disc regeneration through FGF10-FGFR1-CREB pathway and mitochondrial fission.
In Vitro Evaluation of Cadmium-Induced Phosphate Reabsorption Impairment.
Intermittent fasting attenuates ovarian chronic inflammation in obese mice by inhibiting the CXCL12-CXCR4 axis.
Sennoside A alleviates HFD-induced MAFLD by protecting intestinal barrier function through TLR4/NF-κB and mitochondrial quality control.
YAP in synovial macrophages mitigates mechanically-induced osteoarthritis by preserving mitochondrial fusion.
From inhalation to systemic damage: Decoding the mechanistic cascade of silica nanoparticle-induced multi-organ toxicity.
Icariin inhibits autophagy and promotes apoptosis by regulating mitochondrial division in Triple-negative breast cancer.
Lobetyolin alleviates microglial inflammation by activating CK2α/Opa1-mediated mitochondrial fusion in ischemic stroke.
Nobiletin Ameliorates Skeletal Muscle Performance in D-Galactose-Induced Aging Mice by Boosting Aerobic Metabolism.
Endoplasmic Reticulum Stress Induced by Turbulence of Mitochondrial Fusion and Fission Was Involved in Isoproterenol-Induced H9c2 Cell Injury.
Molecular mechanism of berberine in ameliorating leptin resistance and mitochondrial dysfunction through the TRIB1-C/EBPα axis in obesity.
Dynamin-Related Protein 1-Dependent Disruption of Mitochondrial Homeostasis Drives Blue Light-Induced Epithelial-Mesenchymal Transition in Retinal Aging.
Integrative Machine Learning and Experimental Validation Identify FIS1 as a Candidate Biomarker Linked to Mitochondrial Dynamics in Pulmonary Hypertension.
AMPK Deficiency Induces Corneal Epithelial Barrier Dysfunction by Modulating Energy Homeostasis.
The HEAT repeat protein MROH7 regulates the inflammatory macrophage response via LBP acetylation.
Redox switch C674 in SERCA2 triggers Ca(2+)-calcineurin-MCU-Drp1 cascade and pulmonary vascular remodeling.
Integrative Proteomic and Bioenergetic Profiling Reveals Diet- and Strain-Specific Mitochondrial Dysfunction in Cohen Diabetic Rat Hearts.
A coenzyme-based "interface-welding" hydrogel coating for titanium implants promotes diabetic osseointegration by regulating mitochondrial dynamics.
Hippocampal HDAC7 induces perioperative neurocognitive disorders via an NF-κB-MFN2-ACSL4 ferroptosis pathway.
Mitochondrial TRPV1 exacerbates cognitive deficits in sepsis-associated encephalopathy by driving microglial metabolic reprogramming.
GL-V9 disrupts the mitochondrial homeostasis and triggers the integrated stress response by promoting the binding of cytosolic MDM2 with NDUFS1 in colorectal cancer.
Chronic Psychological Stress Activates TRP/TAM/CXCL1 Signaling to Promote Breast Cancer Adipocyte Lipolysis via KEAP1 m(6)A Demethylation.
Astragaloside IV Alleviates H(2)O(2)-Induced Mitochondrial Dysfunction and Inhibits Mitophagy Via PI3K/AKT/mTOR Pathway.
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis.
METTL3-mediated m6A modification regulates D-galactose-induced skin fibroblast senescence through miR-208a-5p.
Calcium dysregulation disrupts mitochondrial homeostasis by interfering AMPK/Drp1 pathway to aggravate plaque progression and instability.
miR-223-3p Mitigates Mitochondrial Dysfunction and Cementoblast Apoptosis in Orthodontic Root Resorption via FoxO3.
Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway.
Kaempferol improves mitochondrial homeostasis via mitochondrial dynamics and mitophagy in diabetic kidney disease.
Gestational zearalenone causes fetal intrauterine growth restriction partially through deriving ROS-Drp1 mediated placental PANoptosis.
Impaired xCT-mediated cystine uptake drives serine and proline metabolic reprogramming and mitochondrial fission in skeletal muscle cells.
Porcine GWAS identifies ACOT11 as regulator for macrophage IL-1β maturation via IFNGR2 palmitoylation.
Oxytocin Regulated Neuroinflammation through OTR/Mitochondria Mediated Pathway to Improve Hypoxia-Induced Brain Injury.
Mechanistic study of the novel peroxidase mimetic DhHP-6 in metabolic cataracts.
Atrazine-induced hippocampal neurotoxicity: Involvement of Drp1-mediated mitochondrial fission.
Preconception paternal exposure to zearalenone impairs male fertility and IVF embryo survival in mice.
OPA1 modulates NLRP3 inflammasome activation and microglial-mediated neuroinflammation in neonatal hypoxic-ischemic brain injury.
Electroacupuncture improves motor function after ischemic stroke via regulating mitochondrial dynamics.
TAAR1 deficiency impairs mitochondrial dynamics and synaptic integrity in the medial prefrontal cortex and associated cognition in mice.
Activin A protects against lipopolysaccharide/TNF-α induced damage of dopaminergic neurons both in vivo and in vitro by regulating mitochondrial fusion.
Effect of disruption of mitochondrial and endoplasmic reticulum calcium homeostasis on neurites in hydrogen peroxide- and ionomycin-treated cells.
Protective effect of astragaloside IV against zinc oxide nanoparticles induced human neuroblastoma SH-SY5Y cell death: a focus on mitochondrial quality control.
YME1L1 Dysfunction Associated With 3-Methylglutaconic Aciduria.
Dual regulation of mitochondrial fusion by Parkin-PINK1 and OMA1.
Leucine 7 is a key residue for mutant huntingtin-induced mitochondrial pathology and neurotoxicity in Huntington's disease.
USP13 inhibition exacerbates mitochondrial dysfunction and acute kidney injury by acting on MCL-1.
Melatonin refines ovarian mitochondrial dysfunction in PCOS by regulating the circadian rhythm gene Clock.
S-nitrosylation of peroxiredoxin 2 exacerbates hyperuricemia-induced renal injury through regulation of mitochondrial homeostasis.
Melatonin ameliorates Pb-induced mitochondrial homeostasis and ovarian damage through regulating the p38 signaling pathway.
Neurotoxicity of Realgar: Crosstalk Between UBXD8-DRP1-Regulated Mitochondrial Fission and PINK1-Parkin-Mediated Mitophagy.
Lycium barbarum polysaccharide alleviate cadmium-induced mitochondrial dysfunction mediated pyroptosis in duck liver.
The crucial function of IDO1 in pulmonary fibrosis: From the perspective of mitochondrial fusion in lung fibroblasts and targeted molecular inhibition.
Schisandrin B regulates mitochondrial dynamics via AKT1 activation and mitochondrial targeting to ameliorate renal ischemia-reperfusion injury.
PFOS causes lysosomes-regulated mitochondrial fission through TRPML1-VDAC1 and oligomerization of MCU/ATP5J2.
PINK1 affects mitochondrial oxidative phosphorylation by regulating MFN2 to alleviate diabetic kidney disease.
Icariin mitigates depressive-like behavior in rats by regulating mitochondrial function.
Differential pathological dynamics triggered by distinct Parkinson patient-derived α-synuclein extracts in nonhuman primates.
Drp1-Mediated Mitochondrial Fission Is Essential for Chemical-Induced Neuronal Transdifferentiation from Human Primary Fibroblasts.
FOXK2 in skeletal muscle development: a new pathogenic gene for congenital myopathy with ptosis.
Extremely low-frequency electromagnetic field (ELF-EMF) enhances mitochondrial energy production in NARP cybrids.
Nicotinamide riboside promoted cardiac energetics and alleviated doxorubicin-induced cardiotoxicity via SIRT1/ERRα signal in human pluripotent stem cells-derived cardiomyocytes.
S-COS-Se mitigates cadmium-induced oxidative stress, inflammation, and immunotoxicity by restoring immune balance and inhibiting mitochondria-pyroptosis crosstalk.
Tang Bi formula alleviates diabetic sciatic neuropathy via AMPK/PGC-1α/MFN2 pathway activation.
Drp1-Dependent Mitochondrial Fission Contributes to Lactic Acid-Induced Chicken Cardiomyocyte Damage.
9-PAHSA ameliorates microvascular damage during cardiac ischaemia/reperfusion injury by promoting LKB1/AMPK/ULK1-mediated autophagy-dependent STING degradation.
Effects of contraction frequency during high-intensity training on fatigue resistance and aerobic adaptations in mouse skeletal muscle.
Compound heterozygous mutation of AFG3L2 causes autosomal recessive spinocerebellar ataxia through mitochondrial impairment and MICU1 mediated Ca(2+) overload.
Olesoxime protects against cisplatin-induced acute kidney injury by attenuating mitochondrial dysfunction.
Ginsenoside Rb3 Promotes Opa1-Mediated Regenerative Neurogenesis via Activating the Ido1 Pathway in Ischemic Stroke.
Elevating VAPB-PTPIP51 integration repairs damaged mitochondria-associated endoplasmic reticulum membranes and inhibits lung fibroblasts activation.
Salidroside protects against myocardial infarction via activating MIF-mediated mitochondrial quality control.
Dexmedetomidine ameliorates hepatic ischemia reperfusion injury via modulating SIRT3 mediated mitochondrial quality control.
PANAXADIOL SAPONIN ALLEVIATES LPS-INDUCED CARDIOMYOPATHY SIMILAR TO DEXAMETHASONE VIA IMPROVING MITOCHONDRIAL QUALITY CONTROL.
Zn(2 +) alleviates ischemia/reperfusion injury in H9c2 cells by modulating mitochondrial biogenesis and dynamics via MCU.
Harmine derivative H-2-168 induces the death of Echinococcus granulosus by regulating mitochondrial fusion and fission.
Roxadustat alleviates cisplatin-induced acute kidney injury by regulating fatty acid oxidation and mitochondrial function.
RAB3GAP2 silencing alleviates oxidative stress in cataracts by enhancing Mfn2-mediated mitochondrial autophagy by activating JNK/STAT3.
Multi-Omics Analysis Reveals Distinct Lipid Remodelling and Mitochondrial Stress in SH-SY5Y Cells Modelling Parkinson's Disease.
Hippocampal cell- and circuit-specific differences in mitochondrial form and function.
Liraglutide alleviates diabetic cardiomyopathy in streptozotocin-induced diabetic rats by enhancing mitophagy mediated by the AMPK-Parkin signaling pathway.
NDUFAB1 promotes hepatocellular carcinoma progression by disrupting mitochondrial homeostasis and mitophagy pathway.
Leber's hereditary optic neuropathy-associated ND1 3733G>C mutation ameliorates the mitochondrial quality control and cellular homeostasis.
Mn(2)O(3) NPs-induced liver injury is potentially associated with gut microbiota dysbiosis in broiler chicken.
Melatonin mitigates arsenic and fluoride-induced cardiotoxicity in chickens by maintaining mitochondrial homeostasis.
Putative PINK1/Parkin activators lower the threshold for mitophagy by sensitizing cells to mitochondrial stress.
NR3C1/GLMN-Mediated FKBP12.6 Ubiquitination Disrupts Calcium Homeostasis and Impairs Mitochondrial Quality Control in Stress-Induced Myocardial Damage.
Mitochondrial ultrastructural pathology in diabetic cardiomyopathy: integrated analysis via scanning electron microscopy and 3D visualization imaging.
Radiocleavable rare-earth nanoactivators targeting over-expressed folate receptors induce mitochondrial dysfunction and remodel immune suppressive microenvironment in pancreatic cancer.
PGAM5 aggravated doxorubicin-induced cardiotoxicity by disturbing mitochondrial dynamics and exacerbating cardiomyocytes apoptosis.
Clioquinol induces mitochondrial toxicity in SH-SY5Y neuroblastoma cells by affecting the respiratory chain complex IV and OPA1 dynamin-like GTPase.
O-GlcNAcylation of hexokinase 2 modulates mitochondrial dynamics and enhances the progression of lung cancer.
sLithospermic acid etched ZIF-8 nanoparticles delays osteoarthritis progression by inhibiting inflammatory signaling pathways and rescuing mitochondrial damage.
Drp1 Promotes Macrophage M1 Polarization and Inflammatory Response in Autoimmune Myocarditis by Driving Mitochondrial Fission.
Xin-Ji-Er-Kang balances mitochondrial fusion and fission to protect cardiomyocytes in mice with heart failure by regulating the ERα/SIRT3 pathway.
β-hydroxybutyrate facilitates mitochondrial-derived vesicle biogenesis and improves mitochondrial functions.
Asparagine transporter supports macrophage inflammation via histone phosphorylation.
A liver-fat crosstalk for iron flux during healthy beiging of adipose tissue.
CD62E- and ROS-Responsive ETS Improves Cartilage Repair by Inhibiting Endothelial Cell Activation through OPA1-Mediated Mitochondrial Homeostasis.
PTPLAD1 Regulates PHB-Raf Interaction to Orchestrate Epithelial-Mesenchymal and Mitofusion-Fission Transitions in Colorectal Cancer.
Loss of MTX2 causes mitochondrial dysfunction, podocyte injury, nephrotic proteinuria and glomerulopathy in mice and patients.
SIRT3 regulates cardiolipin biosynthesis in pressure overload-induced cardiac remodeling by PPARγ-mediated mechanism.
Dl-3-n-butylphthalide attenuates cerebral ischemia/reperfusion injury in mice through AMPK-mediated mitochondrial fusion.
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.
PDK4-mediated Nrf2 inactivation contributes to oxidative stress and diabetic kidney injury.
Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation.
Prophylactic Effects of Betaine on Depression and Anxiety Behaviors in Mice with Dextran Sulfate Sodium-Induced Colitis.
Stearic acid alleviates aortic medial degeneration through maintaining mitochondrial dynamics homeostasis via inhibiting JNK/MAPK signaling.
Melatonin Protects Against Mitochondrial Dyshomeostasis and Ovarian Damage Caused by Chronic Unpredictable Mild Stress Through the eIF2α-AFT4 Signaling Pathway in Mice.
SIRT1 regulates mitochondrial fission to alleviate high altitude hypoxia inducedcardiac dysfunction in rats via the PGC-1α-DRP1/FIS1/MFF pathway.
Homoplantaginin alleviates high glucose-induced vascular endothelial senescence by inhibiting mtDNA-cGAS-STING pathway via blunting DRP1-mitochondrial fission-VDAC1 axis.
Qifu-yin activates the Keap1/Nrf2/ARE signaling and ameliorates synaptic injury and oxidative stress in APP/PS1 mice.
Nr-CWS regulates METTL3-mediated m(6)A modification of CDS2 mRNA in vascular endothelial cells and has prognostic significance.
Apoptosis, Mitochondrial Autophagy, Fission, and Fusion Maintain Mitochondrial Homeostasis in Mouse Liver Under Tail Suspension Conditions.
Yiqihuoxue decoction (GSC) inhibits mitochondrial fission through the AMPK pathway to ameliorate EPCs senescence and optimize vascular aging transplantation regimens.
SGLT2 inhibitor canagliflozin reduces visceral adipose tissue in db/db mice by modulating AMPK/KLF4 signaling and regulating mitochondrial dynamics to induce browning.
Renal denervation ameliorates atrial remodeling in type 2 diabetic rats by regulating mitochondrial dynamics.
Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway.
E3 ubiquitin ligase TRIM31 alleviates dopaminergic neurodegeneration by promoting proteasomal degradation of VDAC1 in Parkinson's Disease model.
Hydrogen Protects Mitochondrial Function by Increasing the Expression of PGC-1α and Ameliorating Myocardial Ischaemia-Reperfusion Injury.
Endothelial Birc3 promotes renal fibrosis through modulating Drp1-mediated mitochondrial fission via MAPK/PI3K/Akt pathway.
Procyanidin C1 ameliorates acidic pH stress induced nucleus pulposus degeneration through SIRT3/FOXO3-mediated mitochondrial dynamics.
Targeting DUSP26 to drive cardiac mitochondrial dynamics via FAK-ERK signaling in diabetic cardiomyopathy.
TRPA1 protects against contrast-induced renal tubular injury by preserving mitochondrial dynamics via the AMPK/DRP1 pathway.
Deafness-associated tRNA(Phe) mutation impaired mitochondrial and cellular integrity.
circUSP13 facilitates the fast-to-slow myofiber shift via the MAPK/ERK signaling pathway in goat skeletal muscles.
Quantitative Proteomics Reveals Manganese Alleviates Heat Stress of Broiler Myocardial Cells via Regulating Nucleic Acid Metabolism.
Doxycycline induces mitochondrial dysfunction in aortic smooth muscle cells.
Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.
Mechanistic of AMPK/ACC2 regulating myoblast differentiation by fatty acid oxidation of goat.
Cytochrome c oxidase IV isoform 1 (COX4-1) regulates the proliferation, migration and invasion of trophoblast cells via modulating mitochondrial function.
HTR1B regulates mitochondrial homeostasis and mitophagy by activating the ERK/ MAPK signalling pathway during human embryonic arrest.
Targeting DRP1 with Mdivi-1 to correct mitochondrial abnormalities in ADOA+ syndrome.
Dulaglutide restores endothelial progenitor cell levels in diabetic mice and mitigates high glucose-induced endothelial injury through SIRT1-mediated mitochondrial fission.
Zearalenone modulates the function of goat endometrial cells via the mitochondrial quality control system.
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
High-fat diet-induced L-saccharopine accumulation inhibits estradiol synthesis and damages oocyte quality by disturbing mitochondrial homeostasis.
Uncovering impaired mitochondrial and lysosomal function in adipose-derived stem cells from obese individuals with altered biological activity.
MCT1-governed pyruvate metabolism is essential for antibody class-switch recombination through H3K27 acetylation.
Melatonin decreases GSDME mediated mesothelial cell pyroptosis and prevents peritoneal fibrosis and ultrafiltration failure.
Intermittent Theta Burst Stimulation Attenuates Cognitive Deficits and Alzheimer's Disease-Type Pathologies via ISCA1-Mediated Mitochondrial Modulation in APP/PS1 Mice.
Chronic Sleep Deprivation Impairs Visual Functions via Oxidative Damage in Mice.
Effects of metformin on glucose metabolism and mitochondrial function in patients with obstructive sleep apnea: A pilot randomized trial.
JianPiYiShen formula prevents cisplatin-induced acute kidney injury in mice by improving necroptosis through MAPK pathway.
Serine synthesis sustains macrophage IL-1β production via NAD(+)-dependent protein acetylation.
Mesenchymal stem cell-loaded hydrogel to inhibit inflammatory reaction in surgical brain injury via mitochondria transfer.
WTAP-mediated m(6)A modification of TRIM22 promotes diabetic nephropathy by inducing mitochondrial dysfunction via ubiquitination of OPA1.
Regulatory roles of histamine receptor in astrocytic glutamate clearance under conditions of increased glucose variability.
New TIPARP inhibitor rescues mitochondrial function and brain injury in ischemic stroke.
IDH1/MDH1 deacetylation promotes NETosis by regulating OPA1 and autophagy.
Aflatoxin B1 Promotes Pyroptosis in IPEC-J2 Cells by Disrupting Mitochondrial Dynamics through the AMPK/NLRP3 Pathway.
Disturbance of mitochondrial dynamics led to spermatogenesis disorder in mice exposed to polystyrene micro- and nanoplastics.
Electroacupuncture improves cognitive impairment after ischemic stroke based on regulation of mitochondrial dynamics through SIRT1/PGC-1α pathway.
Lysosomes drive the piecemeal removal of mitochondrial inner membrane.
Activating MC4R Promotes Functional Recovery by Repressing Oxidative Stress-Mediated AIM2 Activation Post-spinal Cord Injury.
Icariin Ameliorates D-galactose-induced Cell Injury in Neuron-like PC12 Cells by Inhibiting MPTP Opening.
GPRASP2 deficiency contributes to apoptosis in the spiral ganglion cells via the AMPK/DRP1 signaling pathway.
Pathological characteristics of axons and alterations of proteomic and lipidomic profiles in midbrain dopaminergic neurodegeneration induced by WDR45-deficiency.
Matrix stiffness aggravates osteoarthritis progression through H3K27me3 demethylation induced by mitochondrial damage.
Disturbance of mitochondrial dynamics in myocardium of broilers with pulmonary hypertension syndrome.
Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia-reperfusion injury.
Schisandrin B Alleviates LPS Induced Mitochondrial Damage in C28I2 Cells.
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Inhibition of KMO Ameliorates Myocardial Ischemia Injury via Maintaining Mitochondrial Fusion and Fission Balance.
Electroacupuncture Ameliorates Depression-Like Behaviors in Post-Stroke Rats via Activating AMPK-Mediated Mitochondrial Function.
Shenshuaifu Granule Attenuates Acute Kidney Injury by Inhibiting Ferroptosis Mediated by p53/SLC7A11/GPX4 Pathway.
Exercise intervention improves mitochondrial quality in non-alcoholic fatty liver disease zebrafish.
Knock-down of YME1L1 induces mitochondrial dysfunction during early porcine embryonic development.
Aerobic exercise enhances mitochondrial homeostasis to counteract D-galactose-induced sarcopenia in zebrafish.
Mitochondrial miR-12294-5p regulated copper-induced mitochondrial oxidative stress and mitochondrial quality control imbalance by targeted inhibition of CISD1 in chicken livers.
DMT1 differentially regulates mitochondrial complex activities to reduce glutathione loss and mitigate ferroptosis.
Polydatin improves vascular endothelial function by maintaining mitochondrial homeostasis under high glucose conditions.
Down-regulation of the mitochondrial fusion protein Opa1/Mfn2 promotes cardiomyocyte hypertrophy in Su5416/hypoxia-induced pulmonary hypertension rats.
AdipoRon mitigates tau pathology and restores mitochondrial dynamics via AMPK-related pathway in a mouse model of Alzheimer's disease.
High uric acid aggravates apoptosis of lung epithelial cells induced by cigarette smoke extract through downregulating PRDX2 in chronic obstructive pulmonary disease.
QiShenYiQi dripping pill alleviates myocardial ischemia-induced ferroptosis via improving mitochondrial dynamical homeostasis and biogenesis.
SZC-6, a small-molecule activator of SIRT3, attenuates cardiac hypertrophy in mice.
Long-term blue light exposure impairs mitochondrial dynamics in the retina in light-induced retinal degeneration in vivo and in vitro.
NSC228155 alleviates septic cardiomyopathy via protecting mitochondria and inhibiting inflammation.
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
Empagliflozin ameliorates cardiac dysfunction in heart failure mice via regulating mitochondrial dynamics.
Proteomic Characterization of Peritoneal Extracellular Vesicles in a Mouse Model of Peritoneal Fibrosis.
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury.
MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model.
Dexpramipexole ameliorates cognitive deficits in sepsis-associated encephalopathy through suppressing mitochondria-mediated pyroptosis and apoptosis.
Pseudolaric acid B triggers cell apoptosis by activating AMPK/JNK/DRP1/mitochondrial fission pathway in hepatocellular carcinoma.
Identification of mitochondrial related signature associated with immune microenvironment in Alzheimer's disease.
N-acetyl-L-cysteine alleviates FUNDC1-mediated mitophagy by regulating mitochondrial dynamics in type 1 diabetic nephropathy canine.
Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis.
A quantitative proteomic analyses of primary myocardial cell injury induced by heat stress in chicken embryo.
CoLoC-seq probes the global topology of organelle transcriptomes.
Selenium alleviates cadmium-induced mitophagy through FUNDC1-mediated mitochondrial quality control pathway in the lungs of sheep.
SIRT3 promotes metabolic maturation of human iPSC-derived cardiomyocytes via OPA1-controlled mitochondrial dynamics.
Saponins from Panax japonicus improve neuronal mitochondrial injury of aging rats.
Effects of propranolol on glucose metabolism in hemangioma-derived endothelial cells.
Proteomic analysis reveals the aging-related pathways contribute to pulmonary fibrogenesis.
Diosgenin Targets CaMKK2 to Alleviate Type II Diabetic Nephropathy through Improving Autophagy, Mitophagy and Mitochondrial Dynamics.
Ginsenoside Rg1 protects cardiac mitochondrial function via targeting GSTP1 to block S-glutathionylation of optic atrophy 1.
Mitochondrial division inhibitor (mdivi-1) inhibits proliferation and epithelial-mesenchymal transition via the NF-κB pathway in thyroid cancer cells.
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
Mitofilin Heterozygote Mice Display an Increase in Myocardial Injury and Inflammation after Ischemia/Reperfusion.
HIGD2A silencing impairs hepatocellular carcinoma growth via inhibiting mitochondrial function and the MAPK/ERK pathway.
Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2.
Combination of Perindopril Erbumine and Huangqi-Danshen Decoction Protects Against Chronic Kidney Disease via Sirtuin3/Mitochondrial Dynamics Pathway.
COA3 overexpression promotes non-small cell lung cancer metastasis by reprogramming glucose metabolism.
Battery wastewater induces nephrotoxicity via disordering the mitochondrial dynamics.
CERKL, a Retinal Dystrophy Gene, Regulates Mitochondrial Transport and Dynamics in Hippocampal Neurons.
Senescent Phenotype of Astrocytes Leads to Activation of BV2 Microglia and N2a Neuronal Cells Death.
Blocking exosomal secretion aggravates 1,4-benzoquinone-induced mitochondrial fission activated by the AMPK/MFF/Drp1 pathway in HL-60 cells.
Protective Effect of Manganese on Apoptosis and Mitochondrial Function of Heat-Stressed Primary Chick Embryonic Myocardial Cells.
Omentin1 ameliorates myocardial ischemia-induced heart failure via SIRT3/FOXO3a-dependent mitochondrial dynamical homeostasis and mitophagy.
Integrated Analysis of Transcriptome and microRNA Profile Reveals the Toxicity of Euphorbia Factors toward Human Colon Adenocarcinoma Cell Line Caco-2.
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
SIRT4 Expression Ameliorates the Detrimental Effect of Heat Stress via AMPK/mTOR Signaling Pathway in BMECs.
A High-Fat Diet Induces Muscle Mitochondrial Dysfunction and Impairs Swimming Capacity in Zebrafish: A New Model of Sarcopenic Obesity.
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.
HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3.
Environmental cadmium impairs blood-testis barrier via activating HRI-responsive mitochondrial stress in mice.
Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.
Selenium alleviates cadmium-induced aging via mitochondrial quality control in the livers of sheep.
The Mitochondrial PHB2/OMA1/DELE1 Pathway Cooperates with Endoplasmic Reticulum Stress to Facilitate the Response to Chemotherapeutics in Ovarian Cancer.
Herceptin induces ferroptosis and mitochondrial dysfunction in H9c2 cells.
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
Cdk5 Promotes Mitochondrial Fission via Drp1 Phosphorylation at S616 in Chronic Ethanol Exposure-Induced Cognitive Impairment.
Activation of FMS-like tyrosine kinase 3 protects against isoprenaline-induced cardiac hypertrophy by improving autophagy and mitochondrial dynamics.
CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer's disease.
GABA regulates IL-1β production in macrophages.
Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function.
Protective Effect and Mechanism of Melatonin on Cisplatin-Induced Ovarian Damage in Mice.
A pivotal role of selective autophagy in mitochondrial quality control: Implications for zinc oxide nanoparticles induced neurotoxicity.
Phosphorylation of Dynamin-Related Protein 1 (DRP1) Regulates Mitochondrial Dynamics and Skeletal Muscle Wasting in Cancer Cachexia.
Mitochondrial Fusion Potentially Regulates a Metabolic Change in Tibetan Chicken Embryonic Brain During Hypoxia.
Mitochondrial-Targeting Antioxidant SS-31 Suppresses Airway Inflammation and Oxidative Stress Induced by Cigarette Smoke.
RNA-Seq Profiling to Investigate the Mechanism of Qishen Granules on Regulating Mitochondrial Energy Metabolism of Heart Failure in Rats.
Mitochondrial Transplantation Attenuates Cerebral Ischemia-Reperfusion Injury: Possible Involvement of Mitochondrial Component Separation.
Tortoise Plastron and Deer Antler Gelatin Prevents Against Neuronal Mitochondrial Dysfunction In Vitro: Implication for a Potential Therapy of Alzheimer's Disease.
MicroRNA-214 contributes to Ang II-induced cardiac hypertrophy by targeting SIRT3 to provoke mitochondrial malfunction.
Jian-Pi-Yi-Shen formula enhances perindopril inhibition of chronic kidney disease progression by activation of SIRT3, modulation of mitochondrial dynamics, and antioxidant effects.
Melatonin protects against excessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells.
Moderate mechanical stress suppresses the IL-1β-induced chondrocyte apoptosis by regulating mitochondrial dynamics.
Trib1 deficiency causes brown adipose respiratory chain depletion and mitochondrial disorder.
LACTB suppresses melanoma progression by attenuating PP1A and YAP interaction.
Levosimendan in rats decreases acute kidney injury after cardiopulmonary resuscitation by improving mitochondrial dysfunction.
CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson's disease.
The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
Chronic hypoxia alters cardiac mitochondrial complex protein expression and activity in fetal guinea pigs in a sex-selective manner.
CERKL, a retinal dystrophy gene, regulates mitochondrial function and dynamics in the mammalian retina.
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
Inhibition of Cathepsin S Induces Mitochondrial Apoptosis in Glioblastoma Cell Lines Through Mitochondrial Stress and Autophagosome Accumulation.
Lamprey PHB2 maintains mitochondrial stability by tanslocation to the mitochondria under oxidative stress.
PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth.
circ-CBFB upregulates p66Shc to perturb mitochondrial dynamics in APAP-induced liver injury.
AIM2 promotes the development of non-small cell lung cancer by modulating mitochondrial dynamics.
Lactate accelerates vascular calcification through NR4A1-regulated mitochondrial fission and BNIP3-related mitophagy.
Silibinin inhibits migration and invasion of breast cancer MDA-MB-231 cells through induction of mitochondrial fusion.
Fluoride-induced renal dysfunction via respiratory chain complex abnormal expression and fusion elevation in mice.
Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice.
Sodium-glucose cotransporter 2 inhibition attenuates protein overload in renal proximal tubule via suppression of megalin O-GlcNacylation in progressive diabetic nephropathy.
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
Mitochondrial unfolded protein response gene CLPP changes mitochondrial dynamics and affects mitochondrial function.
Mitofusin 2 is involved in chemotaxis of neutrophil-like differentiated HL-60 cells.
Arsenic-induced cardiotoxicity correlates with mitochondrial damage and trace elements imbalance in broiler chickens.
Silibinin-induced apoptosis of breast cancer cells involves mitochondrial impairment.
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Antagonistic effects of selenium on cadmium-induced apoptosis by restoring the mitochondrial dynamic equilibrium and energy metabolism in chicken spleens.
Wang P, Wu Z, Song Z, Deng X, Zhang Y, Gong X
Frontiers in molecular biosciences 2026;13:1778855
Frontiers in molecular biosciences 2026;13:1778855
The purinergic receptor P2rx7 mediated ATP sensing is required to prevent bone aging by directing mitochondrial fitness of MSCs.
Zhuang Z, Han C, Cai M, Li M, Lin S, Chen L, Zhu Z, Zhang H, Xing C, Han B, Yang R
Journal of advanced research 2026 Mar;81:349-364
Journal of advanced research 2026 Mar;81:349-364
Rejuvenation of THY1(+) nucleus pulposus-derived stem cells promotes intervertebral disc regeneration through FGF10-FGFR1-CREB pathway and mitochondrial fission.
Zhai H, Wang Z, Wang S, Liu Z, Zhao D, Zhang Y, Liu K, Kong X, Meng Q, Gu H, Chen L, Zhang Y, Cheng L
Journal of advanced research 2026 Mar 9;
Journal of advanced research 2026 Mar 9;
In Vitro Evaluation of Cadmium-Induced Phosphate Reabsorption Impairment.
Fujishiro H, Nakayama R, Takahashi M, Tamoto A, Taguchi H, Takeuchi K, Himeno S, Sumi D
Journal of applied toxicology : JAT 2026 Mar 5;
Journal of applied toxicology : JAT 2026 Mar 5;
Intermittent fasting attenuates ovarian chronic inflammation in obese mice by inhibiting the CXCL12-CXCR4 axis.
Chen X, Han Z, Yu X, Hao X
International immunopharmacology 2026 Jun 15;179:116603
International immunopharmacology 2026 Jun 15;179:116603
Sennoside A alleviates HFD-induced MAFLD by protecting intestinal barrier function through TLR4/NF-κB and mitochondrial quality control.
Ma L, Yuan C, Cao X, Sun Y
Pathology, research and practice 2026 Jul;283:156482
Pathology, research and practice 2026 Jul;283:156482
YAP in synovial macrophages mitigates mechanically-induced osteoarthritis by preserving mitochondrial fusion.
Cheng Y, Guo ZL, Gu YF, Li WL, Zhang WB
Cellular signalling 2026 Jul;143:112430
Cellular signalling 2026 Jul;143:112430
From inhalation to systemic damage: Decoding the mechanistic cascade of silica nanoparticle-induced multi-organ toxicity.
Ban JQ, Ao LH, Gu HQ, Wei YG, Tian Q, He X, Zhao H, Li J
Toxicology 2026 Jan;519:154310
Toxicology 2026 Jan;519:154310
Icariin inhibits autophagy and promotes apoptosis by regulating mitochondrial division in Triple-negative breast cancer.
Wang W, Zhang X, Gao S, Liu J, Jiang S, Meng Q, Zhang H, Li Y, Shi W, Lv Y
Biochemical pharmacology 2026 Jan;243(Pt 2):117549
Biochemical pharmacology 2026 Jan;243(Pt 2):117549
Lobetyolin alleviates microglial inflammation by activating CK2α/Opa1-mediated mitochondrial fusion in ischemic stroke.
Qin N, Liu R, Deng R, Jia W, Yang Y, Sun J, Gao S, Zhu T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157651
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157651
Nobiletin Ameliorates Skeletal Muscle Performance in D-Galactose-Induced Aging Mice by Boosting Aerobic Metabolism.
Wang H, Zhang Y, Zhang Y, Wang X, Li Y, Ren F, Sun Y
Food science & nutrition 2026 Jan;14(1):e71416
Food science & nutrition 2026 Jan;14(1):e71416
Endoplasmic Reticulum Stress Induced by Turbulence of Mitochondrial Fusion and Fission Was Involved in Isoproterenol-Induced H9c2 Cell Injury.
Zhang S, Chen L, Jia F, Zhang S, Zhang H, Shi W, Cong B
International journal of molecular sciences 2026 Jan 30;27(3)
International journal of molecular sciences 2026 Jan 30;27(3)
Molecular mechanism of berberine in ameliorating leptin resistance and mitochondrial dysfunction through the TRIB1-C/EBPα axis in obesity.
Zhang X, Zhang C, Meng X, Tang J
Chinese medicine 2026 Jan 26;21(1):55
Chinese medicine 2026 Jan 26;21(1):55
Dynamin-Related Protein 1-Dependent Disruption of Mitochondrial Homeostasis Drives Blue Light-Induced Epithelial-Mesenchymal Transition in Retinal Aging.
Li ZY, Yang D, Huang Y, Li Y, Zhao T, Xu Y
Aging cell 2026 Feb;25(2):e70416
Aging cell 2026 Feb;25(2):e70416
Integrative Machine Learning and Experimental Validation Identify FIS1 as a Candidate Biomarker Linked to Mitochondrial Dynamics in Pulmonary Hypertension.
Zhang Y, Dai Q, Gong L, Zheng R, Huang W, Wang F, Yuan R, Song L, Dai A
Cells 2026 Feb 5;15(3)
Cells 2026 Feb 5;15(3)
AMPK Deficiency Induces Corneal Epithelial Barrier Dysfunction by Modulating Energy Homeostasis.
Yang Y, Yan K, Tang Y, Liu Z, Zhu L, Wei M, Huang C, Liu Z, Zhao D, Ren S
Investigative ophthalmology & visual science 2026 Feb 2;67(2):47
Investigative ophthalmology & visual science 2026 Feb 2;67(2):47
The HEAT repeat protein MROH7 regulates the inflammatory macrophage response via LBP acetylation.
Zhang H, Fu J, Guo Y, Liu S, Mei X, Zeng X, Ren W
Cell chemical biology 2026 Feb 19;33(2):169-182.e5
Cell chemical biology 2026 Feb 19;33(2):169-182.e5
Redox switch C674 in SERCA2 triggers Ca(2+)-calcineurin-MCU-Drp1 cascade and pulmonary vascular remodeling.
Chen H, Qiu YX, Xie YF, Chen X, Xiang YY, Zhang HL, Yu WM, Hu PP, Wang LT, Wu FH, Tong XY
Free radical biology & medicine 2026 Feb 16;244:380-394
Free radical biology & medicine 2026 Feb 16;244:380-394
Integrative Proteomic and Bioenergetic Profiling Reveals Diet- and Strain-Specific Mitochondrial Dysfunction in Cohen Diabetic Rat Hearts.
Pavelich L, Arroum T, Pham L, Komnenov D, Stemmer PM, Lax R, Saada A, Weksler-Zangen S, Hüttemann M
Antioxidants (Basel, Switzerland) 2026 Feb 13;15(2)
Antioxidants (Basel, Switzerland) 2026 Feb 13;15(2)
A coenzyme-based "interface-welding" hydrogel coating for titanium implants promotes diabetic osseointegration by regulating mitochondrial dynamics.
Duan Q, Geng W, He T, Yang J, Li K, Yang F, Fu Z, Liao X, Luo H, Zhao P, Cai K
Biomaterials 2026 Aug;331:124115
Biomaterials 2026 Aug;331:124115
Hippocampal HDAC7 induces perioperative neurocognitive disorders via an NF-κB-MFN2-ACSL4 ferroptosis pathway.
Guo J, Chi W, Zhang K, Huang Y, Zhang B, Guo X, Meng F
Cellular signalling 2026 Aug;144:112531
Cellular signalling 2026 Aug;144:112531
Mitochondrial TRPV1 exacerbates cognitive deficits in sepsis-associated encephalopathy by driving microglial metabolic reprogramming.
Fan Z, Du L, Yin L, Liu H, Li M, Li J, Liu F, Yang L, Li J, Wang Q, Wu Y, Ma H, Zhang X
Free radical biology & medicine 2026 Apr;247:448-468
Free radical biology & medicine 2026 Apr;247:448-468
GL-V9 disrupts the mitochondrial homeostasis and triggers the integrated stress response by promoting the binding of cytosolic MDM2 with NDUFS1 in colorectal cancer.
Zhang Y, Xun C, Shi C, Wang R, Gao Y, Pan D, Guo Y, Wei L
Journal of advanced research 2026 Apr 7;
Journal of advanced research 2026 Apr 7;
Chronic Psychological Stress Activates TRP/TAM/CXCL1 Signaling to Promote Breast Cancer Adipocyte Lipolysis via KEAP1 m(6)A Demethylation.
Zhan D, She Y, Zhang X, Zhang J, Wang S, Hong S, Zheng Y, Wang N, Wang Z
Research (Washington, D.C.) 2025;8:0980
Research (Washington, D.C.) 2025;8:0980
Astragaloside IV Alleviates H(2)O(2)-Induced Mitochondrial Dysfunction and Inhibits Mitophagy Via PI3K/AKT/mTOR Pathway.
Qi M, Wang Q, Sun R, Cheng Z, Li M, Fan X, Bai F, Yu J
Cardiovascular therapeutics 2025;2025:9549175
Cardiovascular therapeutics 2025;2025:9549175
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis.
Zhao S, Chen R, An Y, Zhang Y, Ma C, Gao Y, Lu Y, Yang F, Bai X, Zhang J
Frontiers in aging neuroscience 2025;17:1522073
Frontiers in aging neuroscience 2025;17:1522073
METTL3-mediated m6A modification regulates D-galactose-induced skin fibroblast senescence through miR-208a-5p.
Huang G, Sun S, Liao M, Wang J, Yan Q, Li J, Meng Y, Wang Q, Guo Z, Tan J, Li J
Frontiers in immunology 2025;16:1577783
Frontiers in immunology 2025;16:1577783
Calcium dysregulation disrupts mitochondrial homeostasis by interfering AMPK/Drp1 pathway to aggravate plaque progression and instability.
Hu P, Liu M, Wu T, Zhang Y, Liu C, Wang L, Zhang W, Que Y, You J, Yu W, Tong X
Theranostics 2025;15(15):7567-7583
Theranostics 2025;15(15):7567-7583
miR-223-3p Mitigates Mitochondrial Dysfunction and Cementoblast Apoptosis in Orthodontic Root Resorption via FoxO3.
He W, Xu L, Jiang W, Yao S, Fu Y, Cheng Z, Zhang D, Huang L
Journal of periodontal research 2025 Sep;60(9):923-936
Journal of periodontal research 2025 Sep;60(9):923-936
Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway.
Zhang T, Lv H, Jia S, Wang L, Liu W, Ding K, Du X, Hou G, Hou Z, Zhang Y, Zou W, Chen W, Zhu Y
Bone research 2025 Sep 24;13(1):79
Bone research 2025 Sep 24;13(1):79
Kaempferol improves mitochondrial homeostasis via mitochondrial dynamics and mitophagy in diabetic kidney disease.
Xia C, Zhang J, Chen H, Jiang W, Zhou S, Zheng H, Sun W
International immunopharmacology 2025 Sep 23;162:115121
International immunopharmacology 2025 Sep 23;162:115121
Gestational zearalenone causes fetal intrauterine growth restriction partially through deriving ROS-Drp1 mediated placental PANoptosis.
Liu JR, Wu FN, Lin S, Chen C, Liu Y, Fan JW, Hong Q, Chen YH
Ecotoxicology and environmental safety 2025 Sep 1;302:118636
Ecotoxicology and environmental safety 2025 Sep 1;302:118636
Impaired xCT-mediated cystine uptake drives serine and proline metabolic reprogramming and mitochondrial fission in skeletal muscle cells.
Kanaan MN, Karam CY, Kennedy LS, Pileggi CA, Hamilton L, Cuperlovic-Culf M, Harper ME
Redox biology 2025 Oct;86:103839
Redox biology 2025 Oct;86:103839
Porcine GWAS identifies ACOT11 as regulator for macrophage IL-1β maturation via IFNGR2 palmitoylation.
Zhang M, Liu S, Wu Z, Wang C, Zhang H, Yang J, Guo C, Dai M, Wang X, Ren W
Science China. Life sciences 2025 Oct;68(10):3037-3050
Science China. Life sciences 2025 Oct;68(10):3037-3050
Oxytocin Regulated Neuroinflammation through OTR/Mitochondria Mediated Pathway to Improve Hypoxia-Induced Brain Injury.
Yang X, Li K, Chen L, Wang L, Wang X, Lu K, Bai Y, Hou Y, Hou J, Wang C, Cheng X, Oldam J, Yu J, Wu J, Sun B
Molecular neurobiology 2025 Oct;62(10):12907-12923
Molecular neurobiology 2025 Oct;62(10):12907-12923
Mechanistic study of the novel peroxidase mimetic DhHP-6 in metabolic cataracts.
Li Z, Gong P, Tian Y, Wang X, Zhang H
Free radical biology & medicine 2025 Oct;238:450-462
Free radical biology & medicine 2025 Oct;238:450-462
Atrazine-induced hippocampal neurotoxicity: Involvement of Drp1-mediated mitochondrial fission.
Yang J, Qi L, Zhang C, Ding R, Bi H, Li P, Qi Z, Niu Q, Song W, Li J
Chemico-biological interactions 2025 Oct 22;420:111676
Chemico-biological interactions 2025 Oct 22;420:111676
Preconception paternal exposure to zearalenone impairs male fertility and IVF embryo survival in mice.
Wang P, Chen Y, Jiao Y, Zhu Y, Wang M, Ji D, Zou W, Cao Y, Liu Y, Liang D
Chemico-biological interactions 2025 Oct 22;420:111646
Chemico-biological interactions 2025 Oct 22;420:111646
OPA1 modulates NLRP3 inflammasome activation and microglial-mediated neuroinflammation in neonatal hypoxic-ischemic brain injury.
Lv Q, Hong F, Sun Z, Shen H, Lu H, Jin Y, Mao L, Song L
Journal of neuroimmunology 2025 Oct 15;407:578701
Journal of neuroimmunology 2025 Oct 15;407:578701
Electroacupuncture improves motor function after ischemic stroke via regulating mitochondrial dynamics.
Li Z, Ji X, Wang X, Wang J, Lin R, Ma X, Zhang Q, Liang S
Brain research bulletin 2025 Nov;232:111599
Brain research bulletin 2025 Nov;232:111599
TAAR1 deficiency impairs mitochondrial dynamics and synaptic integrity in the medial prefrontal cortex and associated cognition in mice.
Zhang XQ, Xiong J, Liu DN, Zhang CC, Zhang Y, Li JT, Si TM, Su YA
Translational psychiatry 2025 Nov 21;15(1):490
Translational psychiatry 2025 Nov 21;15(1):490
Activin A protects against lipopolysaccharide/TNF-α induced damage of dopaminergic neurons both in vivo and in vitro by regulating mitochondrial fusion.
Zhang Y, Tian S, Niu M, Yang H, Liu L, Kang Y, Yin Y
Neuroscience 2025 Nov 10;587:108-122
Neuroscience 2025 Nov 10;587:108-122
Effect of disruption of mitochondrial and endoplasmic reticulum calcium homeostasis on neurites in hydrogen peroxide- and ionomycin-treated cells.
Hoga K, Wakuzawa M, Nakamura T, Kato Y, Fukui K
Journal of clinical biochemistry and nutrition 2025 May;76(3):253-263
Journal of clinical biochemistry and nutrition 2025 May;76(3):253-263
Protective effect of astragaloside IV against zinc oxide nanoparticles induced human neuroblastoma SH-SY5Y cell death: a focus on mitochondrial quality control.
Wang L, Zhang L, Yun Y, Liang T, Yan C, Mao Z, Zhang J, Liu B, Zhang J, Liang T
Molecular and cellular biochemistry 2025 May;480(5):3079-3095
Molecular and cellular biochemistry 2025 May;480(5):3079-3095
YME1L1 Dysfunction Associated With 3-Methylglutaconic Aciduria.
Demetriadou A, Grafakou O, Georgiou T, Burska D, Malekkou A, Krizova J, Paramera E, Mavrikiou G, Dionysiou M, Theodosiou A, Sismani C, Anastasiadou V, Ioannou I, Papakonstantinou E, Hansikova H, Drousiotou A, Petrou PP
Journal of inherited metabolic disease 2025 May;48(3):e70029
Journal of inherited metabolic disease 2025 May;48(3):e70029
Dual regulation of mitochondrial fusion by Parkin-PINK1 and OMA1.
Yamada T, Ikeda A, Murata D, Wang H, Zhang C, Khare P, Adachi Y, Ito F, Quirós PM, Blackshaw S, López-Otín C, Langer T, Chan DC, Le A, Dawson VL, Dawson TM, Iijima M, Sesaki H
Nature 2025 Mar;639(8055):776-783
Nature 2025 Mar;639(8055):776-783
Leucine 7 is a key residue for mutant huntingtin-induced mitochondrial pathology and neurotoxicity in Huntington's disease.
Zhang S, Wang S, Yang Z, Li Y, Li J, Chen X, Yao H, Zheng Z, Guo X
The Journal of biological chemistry 2025 Mar;301(3):108297
The Journal of biological chemistry 2025 Mar;301(3):108297
USP13 inhibition exacerbates mitochondrial dysfunction and acute kidney injury by acting on MCL-1.
Wang Q, Cao S, Sun Z, Zhu W, Sun L, Li Y, Luo D, Huang S, Zhang Y, Xia W, Zhang A, Jia Z
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167599
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167599
Melatonin refines ovarian mitochondrial dysfunction in PCOS by regulating the circadian rhythm gene Clock.
Chen W, Zhang H, Guo B, Tao Y, Zhang J, Wang J, Chen G, Cheng M, Hong Q, Cao Y, Xie F
Cellular and molecular life sciences : CMLS 2025 Mar 6;82(1):104
Cellular and molecular life sciences : CMLS 2025 Mar 6;82(1):104
S-nitrosylation of peroxiredoxin 2 exacerbates hyperuricemia-induced renal injury through regulation of mitochondrial homeostasis.
Han F, Dong Y, Liu Q, Song L, Guo H, Zhu L, Sun B, Zhao W, Chen L
Free radical biology & medicine 2025 Mar 16;230:66-78
Free radical biology & medicine 2025 Mar 16;230:66-78
Melatonin ameliorates Pb-induced mitochondrial homeostasis and ovarian damage through regulating the p38 signaling pathway.
Yang ZN, Du X, Wang A, Zhao YH, Xia YH, Shi LG, Ding SM, Yue XY, Xing F, Ji DM, Liang D, Zha ZB, Liang CM, Cao YX, Liu YJ
Ecotoxicology and environmental safety 2025 Mar 1;292:117937
Ecotoxicology and environmental safety 2025 Mar 1;292:117937
Neurotoxicity of Realgar: Crosstalk Between UBXD8-DRP1-Regulated Mitochondrial Fission and PINK1-Parkin-Mediated Mitophagy.
Feng R, Liu J, Yao T, Yang Z, Jiang H
Molecular neurobiology 2025 Jun;62(6):7041-7053
Molecular neurobiology 2025 Jun;62(6):7041-7053
Lycium barbarum polysaccharide alleviate cadmium-induced mitochondrial dysfunction mediated pyroptosis in duck liver.
Song J, Luo X, Xiong L, Li S, Chen Y, Liu W, Yuan Y, Ma Y, Bian J, Liu Z, Zou H
International journal of biological macromolecules 2025 Jun;311(Pt 4):143989
International journal of biological macromolecules 2025 Jun;311(Pt 4):143989
The crucial function of IDO1 in pulmonary fibrosis: From the perspective of mitochondrial fusion in lung fibroblasts and targeted molecular inhibition.
Wang L, Ge S, Zhang Y, Feng D, Zhu T, Zhang L, Zhang C
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3125-3148
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3125-3148
Schisandrin B regulates mitochondrial dynamics via AKT1 activation and mitochondrial targeting to ameliorate renal ischemia-reperfusion injury.
Xu C, Wang H, Wang H, Man J, Deng Y, Li Y, Cheng K, Niu J, Gui H, Fu S, Yang L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156672
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156672
PFOS causes lysosomes-regulated mitochondrial fission through TRPML1-VDAC1 and oligomerization of MCU/ATP5J2.
Yang W, Li Y, Feng R, Liang P, Tian K, Hu L, Wang K, Qiu T, Zhang J, Sun X, Yao X
Journal of hazardous materials 2025 Jun 5;489:137685
Journal of hazardous materials 2025 Jun 5;489:137685
PINK1 affects mitochondrial oxidative phosphorylation by regulating MFN2 to alleviate diabetic kidney disease.
Pei X, Liu J, Wei Y, Zhu Y, Li Y, Wang Q, Zhuang L, Jin G
International immunopharmacology 2025 Jun 5;157:114786
International immunopharmacology 2025 Jun 5;157:114786
Icariin mitigates depressive-like behavior in rats by regulating mitochondrial function.
Zhao H, Zhang S, Gong Z, Chen T, Guo H, Yang M, Wang L, Zhou X, Xie J, Li H, Lu Y, Zhu Z
Journal of ethnopharmacology 2025 Jun 26;350:120036
Journal of ethnopharmacology 2025 Jun 26;350:120036
Differential pathological dynamics triggered by distinct Parkinson patient-derived α-synuclein extracts in nonhuman primates.
Kinet R, Bourdenx M, Dovero S, Darricau M, Arotcarena ML, Camus S, Porras G, Thiolat ML, Trigo-Damas I, Bohic S, Morari M, Doudnikoff E, Goikoetxea M, Claverol S, Tokarski C, Kruse N, Mollenhauer B, Estrada C, Garcia-Carrillo N, Herrero MT, Vila M, Obeso JA, Bezard E, Dehay B
Science advances 2025 Jun 20;11(25):eadu6050
Science advances 2025 Jun 20;11(25):eadu6050
Drp1-Mediated Mitochondrial Fission Is Essential for Chemical-Induced Neuronal Transdifferentiation from Human Primary Fibroblasts.
Yang J, Li C, Wang C, Wang X, Liu J, Yu N, Du W, Chi S
Journal of molecular neuroscience : MN 2025 Jun 13;75(2):75
Journal of molecular neuroscience : MN 2025 Jun 13;75(2):75
FOXK2 in skeletal muscle development: a new pathogenic gene for congenital myopathy with ptosis.
Wu P, Song N, Xiang Y, Tao Z, Mao B, Guo R, Wang X, Wu D, Zhang Z, Chen X, Ma D, Zhang T, Hao B, Ma J
EMBO molecular medicine 2025 Jul;17(7):1599-1630
EMBO molecular medicine 2025 Jul;17(7):1599-1630
Extremely low-frequency electromagnetic field (ELF-EMF) enhances mitochondrial energy production in NARP cybrids.
Ito M, Huang Z, Nomura K, Teranishi M, Zhao F, Mino H, Yoneda M, Tanaka M, Ohno K
Scientific reports 2025 Jul 8;15(1):24369
Scientific reports 2025 Jul 8;15(1):24369
Nicotinamide riboside promoted cardiac energetics and alleviated doxorubicin-induced cardiotoxicity via SIRT1/ERRα signal in human pluripotent stem cells-derived cardiomyocytes.
Wang R, Zhang H, Yi Q, Wang YP, Xu H, Tan B, Zhu J
Life sciences 2025 Jul 15;373:123685
Life sciences 2025 Jul 15;373:123685
S-COS-Se mitigates cadmium-induced oxidative stress, inflammation, and immunotoxicity by restoring immune balance and inhibiting mitochondria-pyroptosis crosstalk.
Zheng H, Dong W, Qiu H, Gao S, Hou L, Dong J, Zhao P, Chen F
Ecotoxicology and environmental safety 2025 Jul 15;300:118462
Ecotoxicology and environmental safety 2025 Jul 15;300:118462
Tang Bi formula alleviates diabetic sciatic neuropathy via AMPK/PGC-1α/MFN2 pathway activation.
Yang C, Yu H, Zhou L, Su H, Li X, Qi W, Lian F
Scientific reports 2025 Jul 11;15(1):25069
Scientific reports 2025 Jul 11;15(1):25069
Drp1-Dependent Mitochondrial Fission Contributes to Lactic Acid-Induced Chicken Cardiomyocyte Damage.
Hu D, Cui Y, Hou X, Wang X, Shen Z, Pang H, Ge Y, Ning H
Journal of biochemical and molecular toxicology 2025 Jan;39(1):e70128
Journal of biochemical and molecular toxicology 2025 Jan;39(1):e70128
9-PAHSA ameliorates microvascular damage during cardiac ischaemia/reperfusion injury by promoting LKB1/AMPK/ULK1-mediated autophagy-dependent STING degradation.
Liu W, Hu J, Wang Y, Gan T, Ding Y, Wang X, Xu Q, Xiong J, Xiong N, Lu S, Wang Y, Wang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156241
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156241
Effects of contraction frequency during high-intensity training on fatigue resistance and aerobic adaptations in mouse skeletal muscle.
Naito A, Sato T, Kimura I, Tokuda N, Yamauchi N, Fusagawa H, Yamada T
Journal of applied physiology (Bethesda, Md. : 1985) 2025 Jan 1;138(1):107-120
Journal of applied physiology (Bethesda, Md. : 1985) 2025 Jan 1;138(1):107-120
Compound heterozygous mutation of AFG3L2 causes autosomal recessive spinocerebellar ataxia through mitochondrial impairment and MICU1 mediated Ca(2+) overload.
Li H, Ma Q, Xue Y, Cai L, Bao L, Hong L, Zeng Y, Huang SZ, Finnell RH, Zeng F
Science China. Life sciences 2025 Feb;68(2):484-501
Science China. Life sciences 2025 Feb;68(2):484-501
Olesoxime protects against cisplatin-induced acute kidney injury by attenuating mitochondrial dysfunction.
Wang P, Ouyang J, Zhou K, Hu D, Zhang S, Zhang A, Yang Y
Biomedical journal 2025 Feb;48(1):100730
Biomedical journal 2025 Feb;48(1):100730
Ginsenoside Rb3 Promotes Opa1-Mediated Regenerative Neurogenesis via Activating the Ido1 Pathway in Ischemic Stroke.
Wang L, Qin N, Gao S, Zhu T
Phytotherapy research : PTR 2025 Feb;39(2):564-580
Phytotherapy research : PTR 2025 Feb;39(2):564-580
Elevating VAPB-PTPIP51 integration repairs damaged mitochondria-associated endoplasmic reticulum membranes and inhibits lung fibroblasts activation.
Ban J, Tian H, Wei Y, Ao L, Gu H, Zeng J, Peng X, Ao C, Zhang Y, He X, Zhao H, Li J
International immunopharmacology 2025 Feb 6;147:113982
International immunopharmacology 2025 Feb 6;147:113982
Salidroside protects against myocardial infarction via activating MIF-mediated mitochondrial quality control.
You B, Zhang J, Yang C, Dun Y, Qi D, Long Y, Cheng J, Lin Y, Zhou N, Zeng T, Dong J, Liu S
Chinese medicine 2025 Feb 28;20(1):27
Chinese medicine 2025 Feb 28;20(1):27
Dexmedetomidine ameliorates hepatic ischemia reperfusion injury via modulating SIRT3 mediated mitochondrial quality control.
Ning X, Tang J, Li X, Wang J, Zhai F, Jiang C, Zhang S
Scientific reports 2025 Feb 15;15(1):5630
Scientific reports 2025 Feb 15;15(1):5630
PANAXADIOL SAPONIN ALLEVIATES LPS-INDUCED CARDIOMYOPATHY SIMILAR TO DEXAMETHASONE VIA IMPROVING MITOCHONDRIAL QUALITY CONTROL.
Yang Z, Gao Y, Li D, Zhao L, Du Y
Shock (Augusta, Ga.) 2025 Feb 1;63(2):282-291
Shock (Augusta, Ga.) 2025 Feb 1;63(2):282-291
Zn(2 +) alleviates ischemia/reperfusion injury in H9c2 cells by modulating mitochondrial biogenesis and dynamics via MCU.
Wang B, Xing B, Huang L, Li X, Bian X, Xi J
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Dec;92:127769
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Dec;92:127769
Harmine derivative H-2-168 induces the death of Echinococcus granulosus by regulating mitochondrial fusion and fission.
Gong Y, Zhao M, Pan M, Zhao Y, Liu J, Wen H, Wang J
Pharmaceutical biology 2025 Dec;63(1):188-200
Pharmaceutical biology 2025 Dec;63(1):188-200
Roxadustat alleviates cisplatin-induced acute kidney injury by regulating fatty acid oxidation and mitochondrial function.
Li X, Hu Y, Li J, Shi Y, Zhong Q, Ma X, Jiang D, Zhang S, Zhuang S, Liu N
Renal failure 2025 Dec;47(1):2561218
Renal failure 2025 Dec;47(1):2561218
RAB3GAP2 silencing alleviates oxidative stress in cataracts by enhancing Mfn2-mediated mitochondrial autophagy by activating JNK/STAT3.
Huang Y, Liu Q, Chen L, Tan X, Zeng D, Zhang Y, Qin J, Zeng F, Wei X, Zhong Q, Zhang J, Yuan D
International journal of biological macromolecules 2025 Dec;334(Pt 2):149102
International journal of biological macromolecules 2025 Dec;334(Pt 2):149102
Multi-Omics Analysis Reveals Distinct Lipid Remodelling and Mitochondrial Stress in SH-SY5Y Cells Modelling Parkinson's Disease.
Wang S, Ni Z, Wang G, Zhang J, Tan Y, Hong E, Wang Y, Chen H, Hou H, Hu Q
Metabolites 2025 Dec 4;15(12)
Metabolites 2025 Dec 4;15(12)
Hippocampal cell- and circuit-specific differences in mitochondrial form and function.
Alsalman M, Turner L, Pannoni K, Tarannum R, Desai R, Swanger SA, Farris S
bioRxiv : the preprint server for biology 2025 Dec 17;
bioRxiv : the preprint server for biology 2025 Dec 17;
Liraglutide alleviates diabetic cardiomyopathy in streptozotocin-induced diabetic rats by enhancing mitophagy mediated by the AMPK-Parkin signaling pathway.
Zhu YX, Zhang W, Qu HL, Zhang Y, Zhou RQ, Li P, Wang F, Zhang Y, Liu HH, Li S, Dong Q, Dou KF, Guo YL, Li JJ, Xu RX
World journal of diabetes 2025 Dec 15;16(12):112423
World journal of diabetes 2025 Dec 15;16(12):112423
NDUFAB1 promotes hepatocellular carcinoma progression by disrupting mitochondrial homeostasis and mitophagy pathway.
Yao Z, Tan X, Cui H, Liang H, Zhong A, Man Y, Yi T, Zhang Z, Guo X, Tan S, Zhu X
International immunopharmacology 2025 Dec 10;167:115664
International immunopharmacology 2025 Dec 10;167:115664
Leber's hereditary optic neuropathy-associated ND1 3733G>C mutation ameliorates the mitochondrial quality control and cellular homeostasis.
Yasheng M, Ji Y, He Y, Yi Q, Zhang H, Shan W, Wang K, Zhang J, Li Y, Meng F, Zhang M, Mo JQ, Wei S, Guan MX
The Journal of biological chemistry 2025 Aug;301(8):110464
The Journal of biological chemistry 2025 Aug;301(8):110464
Mn(2)O(3) NPs-induced liver injury is potentially associated with gut microbiota dysbiosis in broiler chicken.
Li Y, Yi J, Liu K, Liu X, Yangzom C, Pan J, Iqbal M, Hu L, Tang Z, Li Y, Zhang H
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Aug;202:115487
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Aug;202:115487
Melatonin mitigates arsenic and fluoride-induced cardiotoxicity in chickens by maintaining mitochondrial homeostasis.
Yuan X, Wen B, Hu X, Yang M, Han L, Zhao S, Zhang J, Ma Y
Poultry science 2025 Aug;104(8):105325
Poultry science 2025 Aug;104(8):105325
Putative PINK1/Parkin activators lower the threshold for mitophagy by sensitizing cells to mitochondrial stress.
Rosencrans WM, Lee RW, McGraw L, Horsburgh I, Wang TY, Quan B, Huynh D, Johnston JA, Chan DC, Chou TF
Science advances 2025 Aug 29;11(35):eady0240
Science advances 2025 Aug 29;11(35):eady0240
NR3C1/GLMN-Mediated FKBP12.6 Ubiquitination Disrupts Calcium Homeostasis and Impairs Mitochondrial Quality Control in Stress-Induced Myocardial Damage.
Cong J, Liu L, Shi R, He M, An Y, Feng X, Yin X, Li Y, Cong B, Shi W
International journal of molecular sciences 2025 Aug 25;26(17)
International journal of molecular sciences 2025 Aug 25;26(17)
Mitochondrial ultrastructural pathology in diabetic cardiomyopathy: integrated analysis via scanning electron microscopy and 3D visualization imaging.
Wang B, Dai L, Liang H, He J, Zhou J, Guan Y, Wang H
Cardiovascular diabetology 2025 Aug 13;24(1):331
Cardiovascular diabetology 2025 Aug 13;24(1):331
Radiocleavable rare-earth nanoactivators targeting over-expressed folate receptors induce mitochondrial dysfunction and remodel immune suppressive microenvironment in pancreatic cancer.
Gupta T, Wu SR, Chang LC, Lin FC, Shan YS, Yeh CS, Su WP
Journal of nanobiotechnology 2025 Aug 12;23(1):562
Journal of nanobiotechnology 2025 Aug 12;23(1):562
PGAM5 aggravated doxorubicin-induced cardiotoxicity by disturbing mitochondrial dynamics and exacerbating cardiomyocytes apoptosis.
He W, Wang J, He W, Zeng L, Zhao R, Qiu K, Tong G, Sun Z, He P
Free radical biology & medicine 2025 Aug 1;235:95-108
Free radical biology & medicine 2025 Aug 1;235:95-108
Clioquinol induces mitochondrial toxicity in SH-SY5Y neuroblastoma cells by affecting the respiratory chain complex IV and OPA1 dynamin-like GTPase.
Katsuyama M, Arakawa N, Yaoi T, Kimura E, Matsumoto M, Iwata K, Umemura A, Yabe-Nishimura C
FEBS letters 2025 Apr;599(8):1135-1145
FEBS letters 2025 Apr;599(8):1135-1145
O-GlcNAcylation of hexokinase 2 modulates mitochondrial dynamics and enhances the progression of lung cancer.
Panpan SI, Wei GE, Kaiming WU, Zhang R
Molecular and cellular biochemistry 2025 Apr;480(4):2633-2643
Molecular and cellular biochemistry 2025 Apr;480(4):2633-2643
sLithospermic acid etched ZIF-8 nanoparticles delays osteoarthritis progression by inhibiting inflammatory signaling pathways and rescuing mitochondrial damage.
Zhang Y, Lou Q, Lian H, Yang R, Cui R, Wang L, Ma B, Hou L, Jin L, Teng W
Materials today. Bio 2025 Apr;31:101589
Materials today. Bio 2025 Apr;31:101589
Drp1 Promotes Macrophage M1 Polarization and Inflammatory Response in Autoimmune Myocarditis by Driving Mitochondrial Fission.
Lin L, Wei J, Xue J, Fan G, Zhu W, Zhu Y, Wu R
Journal of cardiovascular translational research 2025 Apr;18(2):237-246
Journal of cardiovascular translational research 2025 Apr;18(2):237-246
Xin-Ji-Er-Kang balances mitochondrial fusion and fission to protect cardiomyocytes in mice with heart failure by regulating the ERα/SIRT3 pathway.
Cai WW, Qin YY, Ge F, Zhou Q, Huang L, Yang PB, Xia J, Li KK, Hou YF, Wu JM, Wang DY, You Y, Lu WJ, Gao S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156420
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156420
β-hydroxybutyrate facilitates mitochondrial-derived vesicle biogenesis and improves mitochondrial functions.
Tang M, Tu Y, Gong Y, Yang Q, Wang J, Zhang Z, Qin J, Niu S, Yi J, Shang Z, Chen H, Tang Y, Huang Q, Liu Y, Billadeau DD, Liu X, Dai L, Jia D
Molecular cell 2025 Apr 3;85(7):1395-1410.e5
Molecular cell 2025 Apr 3;85(7):1395-1410.e5
Asparagine transporter supports macrophage inflammation via histone phosphorylation.
Wang C, Ye Y, Zhao M, Chen Q, Liu B, Ren W
Science advances 2025 Apr 11;11(15):eads3506
Science advances 2025 Apr 11;11(15):eads3506
A liver-fat crosstalk for iron flux during healthy beiging of adipose tissue.
Yang J, Shi L, Cubito AL, Collins JF, Cheng Z
Autophagy reports 2024;3(1):2396696
Autophagy reports 2024;3(1):2396696
CD62E- and ROS-Responsive ETS Improves Cartilage Repair by Inhibiting Endothelial Cell Activation through OPA1-Mediated Mitochondrial Homeostasis.
Tu P, Pan Y, Wang L, Li B, Sun X, Liang Z, Liu M, Zhao Z, Wu C, Wang J, Wang Z, Song Y, Zhang Y, Ma Y, Guo Y
Biomaterials research 2024;28:0006
Biomaterials research 2024;28:0006
PTPLAD1 Regulates PHB-Raf Interaction to Orchestrate Epithelial-Mesenchymal and Mitofusion-Fission Transitions in Colorectal Cancer.
Huang ZJ, Li YJ, Yang J, Huang L, Zhao Q, Lu YF, Hu Y, Zhang WX, Liang JZ, Pan J, Pan YL, He QY, Wang Y
International journal of biological sciences 2024;20(6):2202-2218
International journal of biological sciences 2024;20(6):2202-2218
Loss of MTX2 causes mitochondrial dysfunction, podocyte injury, nephrotic proteinuria and glomerulopathy in mice and patients.
Li T, Bao Y, Xia Y, Meng H, Zhou C, Huang L, Wang X, Lai EY, Jiang P, Mao J
International journal of biological sciences 2024;20(3):937-952
International journal of biological sciences 2024;20(3):937-952
SIRT3 regulates cardiolipin biosynthesis in pressure overload-induced cardiac remodeling by PPARγ-mediated mechanism.
Liu LX, Zheng XH, Hai JH, Zhang CM, Ti Y, Chen TS, Bu PL
PloS one 2024;19(4):e0301990
PloS one 2024;19(4):e0301990
Dl-3-n-butylphthalide attenuates cerebral ischemia/reperfusion injury in mice through AMPK-mediated mitochondrial fusion.
Zhu T, Dong S, Qin N, Liu R, Shi L, Wan Q
Frontiers in pharmacology 2024;15:1357953
Frontiers in pharmacology 2024;15:1357953
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.
Wang Y, Bai Y, Cai Y, Zhang Y, Shen L, Xi W, Zhou Z, Xu L, Liu X, Han B, Yao H
Theranostics 2024;14(19):7292-7308
Theranostics 2024;14(19):7292-7308
PDK4-mediated Nrf2 inactivation contributes to oxidative stress and diabetic kidney injury.
Tian S, Yang X, Lin Y, Li X, Zhou S, Yu P, Zhao Y
Cellular signalling 2024 Sep;121:111282
Cellular signalling 2024 Sep;121:111282
Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation.
Zhou J, Zhang L, Peng J, Zhang X, Zhang F, Wu Y, Huang A, Du F, Liao Y, He Y, Xie Y, Gu L, Kuang C, Ou W, Xie M, Tu T, Pang J, Zhang D, Guo K, Feng Y, Yin S, Cao Y, Li T, Jiang Y
Cell metabolism 2024 Sep 3;36(9):2054-2068.e14
Cell metabolism 2024 Sep 3;36(9):2054-2068.e14
Prophylactic Effects of Betaine on Depression and Anxiety Behaviors in Mice with Dextran Sulfate Sodium-Induced Colitis.
Liu W, Zhong X, Yi Y, Xie L, Zhou W, Cao W, Chen L
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21041-21051
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21041-21051
Stearic acid alleviates aortic medial degeneration through maintaining mitochondrial dynamics homeostasis via inhibiting JNK/MAPK signaling.
Wang K, Xie X, Hu X, Wang Z, Xia J, Wu Q
iScience 2024 Sep 20;27(9):110594
iScience 2024 Sep 20;27(9):110594
Melatonin Protects Against Mitochondrial Dyshomeostasis and Ovarian Damage Caused by Chronic Unpredictable Mild Stress Through the eIF2α-AFT4 Signaling Pathway in Mice.
Ding SM, Shi LG, Xing F, Cui SS, Cheng HR, Liu Y, Ji DM, Liang D, Cao YX, Liu YJ
Reproductive sciences (Thousand Oaks, Calif.) 2024 Oct;31(10):3191-3201
Reproductive sciences (Thousand Oaks, Calif.) 2024 Oct;31(10):3191-3201
SIRT1 regulates mitochondrial fission to alleviate high altitude hypoxia inducedcardiac dysfunction in rats via the PGC-1α-DRP1/FIS1/MFF pathway.
Xu H, Song X, Zhang X, Wang G, Cheng X, Zhang L, Wang Z, Li R, Ai C, Wang X, Pu L, Chen Z, Liu W
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1663-1678
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1663-1678
Homoplantaginin alleviates high glucose-induced vascular endothelial senescence by inhibiting mtDNA-cGAS-STING pathway via blunting DRP1-mitochondrial fission-VDAC1 axis.
Wang L, Zhang X, Huang X, Sha X, Li X, Zheng J, Li S, Wei Z, Wu F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Oct 31;38(20):e70127
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Oct 31;38(20):e70127
Qifu-yin activates the Keap1/Nrf2/ARE signaling and ameliorates synaptic injury and oxidative stress in APP/PS1 mice.
Wang S, Huang J, Chen Y, Liang Y, Chen L, Ye D, Yang H, Hui Z, Wang X, Zhang Z, Zhu X
Journal of ethnopharmacology 2024 Oct 28;333:118497
Journal of ethnopharmacology 2024 Oct 28;333:118497
Nr-CWS regulates METTL3-mediated m(6)A modification of CDS2 mRNA in vascular endothelial cells and has prognostic significance.
Zhang J, Chen F, Wei W, Ning Q, Zhu D, Fan J, Wang H, Wang J, Zhang A, Jin P, Li Q
Communications biology 2024 Oct 18;7(1):1348
Communications biology 2024 Oct 18;7(1):1348
Apoptosis, Mitochondrial Autophagy, Fission, and Fusion Maintain Mitochondrial Homeostasis in Mouse Liver Under Tail Suspension Conditions.
Li LF, Yu J, Li R, Li SS, Huang JY, Wang MD, Jiang LN, Xu JH, Wang Z
International journal of molecular sciences 2024 Oct 18;25(20)
International journal of molecular sciences 2024 Oct 18;25(20)
Yiqihuoxue decoction (GSC) inhibits mitochondrial fission through the AMPK pathway to ameliorate EPCs senescence and optimize vascular aging transplantation regimens.
Liu Y, Niu Z, Wang X, Xiu C, Hu Y, Wang J, Lei Y, Yang J
Chinese medicine 2024 Oct 14;19(1):143
Chinese medicine 2024 Oct 14;19(1):143
SGLT2 inhibitor canagliflozin reduces visceral adipose tissue in db/db mice by modulating AMPK/KLF4 signaling and regulating mitochondrial dynamics to induce browning.
Qu J, Tian L, Zhang M, Sun B, Chen L
Molecular and cellular endocrinology 2024 Oct 1;592:112320
Molecular and cellular endocrinology 2024 Oct 1;592:112320
Renal denervation ameliorates atrial remodeling in type 2 diabetic rats by regulating mitochondrial dynamics.
Huo JY, Hou C, Li XL, Yang L, Jiang WY
Journal of physiology and biochemistry 2024 Nov;80(4):935-948
Journal of physiology and biochemistry 2024 Nov;80(4):935-948
Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway.
Lan X, Wang Q, Liu Y, You Q, Wei W, Zhu C, Hai D, Cai Z, Yu J, Zhang J, Liu N
Redox biology 2024 Nov;77:103406
Redox biology 2024 Nov;77:103406
E3 ubiquitin ligase TRIM31 alleviates dopaminergic neurodegeneration by promoting proteasomal degradation of VDAC1 in Parkinson's Disease model.
Zhao Z, Song X, Wang Y, Yu L, Huang G, Li Y, Zong R, Liu T, Ji Q, Zheng Y, Liu B, Zhu Q, Chen L, Gao C, Liu H
Cell death and differentiation 2024 Nov;31(11):1410-1421
Cell death and differentiation 2024 Nov;31(11):1410-1421
Hydrogen Protects Mitochondrial Function by Increasing the Expression of PGC-1α and Ameliorating Myocardial Ischaemia-Reperfusion Injury.
Zuo Y, Wang J, Gong Z, Wang Y, Wang Q, Yang X, Liu F, Liu T
Journal of cellular and molecular medicine 2024 Nov;28(22):e70236
Journal of cellular and molecular medicine 2024 Nov;28(22):e70236
Endothelial Birc3 promotes renal fibrosis through modulating Drp1-mediated mitochondrial fission via MAPK/PI3K/Akt pathway.
Chen S, He Q, Yang H, Huang H
Biochemical pharmacology 2024 Nov;229:116477
Biochemical pharmacology 2024 Nov;229:116477
Procyanidin C1 ameliorates acidic pH stress induced nucleus pulposus degeneration through SIRT3/FOXO3-mediated mitochondrial dynamics.
Hua W, Xie L, Dong C, Yang G, Chi S, Xu Z, Yang C, Wang H, Wu X
Journal of translational medicine 2024 Nov 27;22(1):1071
Journal of translational medicine 2024 Nov 27;22(1):1071
Targeting DUSP26 to drive cardiac mitochondrial dynamics via FAK-ERK signaling in diabetic cardiomyopathy.
Liu C, Xu X, Sun G, Song C, Jiang S, Sun P, Tian J
Free radical biology & medicine 2024 Nov 20;225:856-870
Free radical biology & medicine 2024 Nov 20;225:856-870
TRPA1 protects against contrast-induced renal tubular injury by preserving mitochondrial dynamics via the AMPK/DRP1 pathway.
Wang X, Luo T, Yang Y, Yang L, Liu M, Zou Q, Wang D, Yang C, Xue Q, Liu S, Wan J, He G, Zeng A, Hou J, Ma S, Wang P
Free radical biology & medicine 2024 Nov 1;224:521-539
Free radical biology & medicine 2024 Nov 1;224:521-539
Deafness-associated tRNA(Phe) mutation impaired mitochondrial and cellular integrity.
Chen X, Meng F, Chen C, Li S, Chou Z, Xu B, Mo JQ, Guo Y, Guan MX
The Journal of biological chemistry 2024 May;300(5):107235
The Journal of biological chemistry 2024 May;300(5):107235
circUSP13 facilitates the fast-to-slow myofiber shift via the MAPK/ERK signaling pathway in goat skeletal muscles.
Zhang Z, Kang Z, Deng K, Li J, Liu Z, Huang X, Wang F, Fan Y
Journal of cellular physiology 2024 May;239(5):e31226
Journal of cellular physiology 2024 May;239(5):e31226
Quantitative Proteomics Reveals Manganese Alleviates Heat Stress of Broiler Myocardial Cells via Regulating Nucleic Acid Metabolism.
Qin S, Wang R, Li J, Tang D, Shi Z
Biological trace element research 2024 Mar;202(3):1187-1202
Biological trace element research 2024 Mar;202(3):1187-1202
Doxycycline induces mitochondrial dysfunction in aortic smooth muscle cells.
Yap C, Wanga S, Wüst RCI, van Os BW, Pijls MME, Keijzer S, van Zanten E, Koolbergen DR, Driessen AHG, Balm R, Yeung KK, de Vries CJM, Houtkooper RH, Lindeman JHN, de Waard V
Vascular pharmacology 2024 Mar;154:107279
Vascular pharmacology 2024 Mar;154:107279
Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.
Shi L, Yang J, Tao Z, Zheng L, Bui TF, Alonso RL, Yue F, Cheng Z
Clinical science (London, England : 1979) 2024 Mar 20;138(6):371-385
Clinical science (London, England : 1979) 2024 Mar 20;138(6):371-385
Mechanistic of AMPK/ACC2 regulating myoblast differentiation by fatty acid oxidation of goat.
Kang Z, Zhang Z, Li J, Deng K, Wang F, Fan Y
International journal of biological macromolecules 2024 Jun;270(Pt 2):132243
International journal of biological macromolecules 2024 Jun;270(Pt 2):132243
Cytochrome c oxidase IV isoform 1 (COX4-1) regulates the proliferation, migration and invasion of trophoblast cells via modulating mitochondrial function.
Yu J, Duan Y, Lu Q, Chen M, Ning F, Ye Y, Lu S, Ou D, Sha X, Gan X, Zhao M, Lash GE
Placenta 2024 Jun;151:48-58
Placenta 2024 Jun;151:48-58
HTR1B regulates mitochondrial homeostasis and mitophagy by activating the ERK/ MAPK signalling pathway during human embryonic arrest.
Ding SM, Shi LG, Cao ZP, Zhu NN, Liu YY, Wang MY, Cui SS, Cheng HR, Liang D, Cao YX, Liu YJ
Heliyon 2024 Jun 30;10(12):e33132
Heliyon 2024 Jun 30;10(12):e33132
Targeting DRP1 with Mdivi-1 to correct mitochondrial abnormalities in ADOA+ syndrome.
Lin Y, Wang D, Li B, Wang J, Xu L, Sun X, Ji K, Yan C, Liu F, Zhao Y
JCI insight 2024 Jun 25;9(15)
JCI insight 2024 Jun 25;9(15)
Dulaglutide restores endothelial progenitor cell levels in diabetic mice and mitigates high glucose-induced endothelial injury through SIRT1-mediated mitochondrial fission.
Mei X, Li Y, Wu J, Liao L, Lu D, Qiu P, Yang HL, Tang MW, Liang XY, Liu D
Biochemical and biophysical research communications 2024 Jul 5;716:150002
Biochemical and biophysical research communications 2024 Jul 5;716:150002
Zearalenone modulates the function of goat endometrial cells via the mitochondrial quality control system.
Zhang G, Zeng C, Sun X, Zhang Q, Wang Y, Xia R, Mai Q, Xue G, Huang H, Wang F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23701
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23701
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
Yang C, Luo P, Yang YT, Fu XL, Li BX, Shen X, Xu DN, Huang YM, Tian YB, Liu WJ
Poultry science 2024 Jan;103(1):103247
Poultry science 2024 Jan;103(1):103247
High-fat diet-induced L-saccharopine accumulation inhibits estradiol synthesis and damages oocyte quality by disturbing mitochondrial homeostasis.
Wen J, Feng Y, Xue L, Yuan S, Chen Q, Luo A, Wang S, Zhang J
Gut microbes 2024 Jan-Dec;16(1):2412381
Gut microbes 2024 Jan-Dec;16(1):2412381
Uncovering impaired mitochondrial and lysosomal function in adipose-derived stem cells from obese individuals with altered biological activity.
Wang B, Zhang G, Hu Y, Mohsin A, Chen Z, Hao W, Li Z, Gao WQ, Guo M, Xu H
Stem cell research & therapy 2024 Jan 8;15(1):12
Stem cell research & therapy 2024 Jan 8;15(1):12
MCT1-governed pyruvate metabolism is essential for antibody class-switch recombination through H3K27 acetylation.
Chi W, Kang N, Sheng L, Liu S, Tao L, Cao X, Liu Y, Zhu C, Zhang Y, Wu B, Chen R, Cheng L, Wang J, Sun X, Liu X, Deng H, Yang J, Li Z, Liu W, Chen L
Nature communications 2024 Jan 2;15(1):163
Nature communications 2024 Jan 2;15(1):163
Melatonin decreases GSDME mediated mesothelial cell pyroptosis and prevents peritoneal fibrosis and ultrafiltration failure.
Ruan H, Li X, Zhou L, Zheng Z, Hua R, Wang X, Wang Y, Fan Y, Guo S, Wang L, Ur Rahman S, Wang Z, Wei Y, Yu S, Zhang R, Cheng Q, Sheng J, Li X, Liu X, Yuan R, Zhang X, Chen L, Xu G, Guan Y, Nie J, Qin H, Zheng F
Science China. Life sciences 2024 Feb;67(2):360-378
Science China. Life sciences 2024 Feb;67(2):360-378
Intermittent Theta Burst Stimulation Attenuates Cognitive Deficits and Alzheimer's Disease-Type Pathologies via ISCA1-Mediated Mitochondrial Modulation in APP/PS1 Mice.
Zhu Y, Huang H, Chen Z, Tao Y, Liao LY, Gao SH, Wang YJ, Gao CY
Neuroscience bulletin 2024 Feb;40(2):182-200
Neuroscience bulletin 2024 Feb;40(2):182-200
Chronic Sleep Deprivation Impairs Visual Functions via Oxidative Damage in Mice.
Tang L, Zhang H, Liao Y, Zhou S, Yang Y, Zhang M, Guo Y, Xie T, Chen S, Ouyang W, Lin X, Wang S, Huang C, Zhang M, Zhuang J, Zhao J, Zhang R, Zhang C, Jin Z, Hu J, Liu Z
The American journal of pathology 2024 Feb;194(2):307-320
The American journal of pathology 2024 Feb;194(2):307-320
Effects of metformin on glucose metabolism and mitochondrial function in patients with obstructive sleep apnea: A pilot randomized trial.
Zunica ERM, Heintz EC, Dantas WS, Hebert RC, Tanksley M, Beyl RA, Mader EC Jr, Kirwan JP, Axelrod CL, Singh P
Physiological reports 2024 Feb;12(3):e15948
Physiological reports 2024 Feb;12(3):e15948
JianPiYiShen formula prevents cisplatin-induced acute kidney injury in mice by improving necroptosis through MAPK pathway.
Li Z, He R, Liu J, Jin X, Jiang B, Lao Y, Yang S
BMC complementary medicine and therapies 2024 Feb 24;24(1):101
BMC complementary medicine and therapies 2024 Feb 24;24(1):101
Serine synthesis sustains macrophage IL-1β production via NAD(+)-dependent protein acetylation.
Wang C, Chen Q, Chen S, Fan L, Gan Z, Zhao M, Shi L, Bin P, Yang G, Zhou X, Ren W
Molecular cell 2024 Feb 15;84(4):744-759.e6
Molecular cell 2024 Feb 15;84(4):744-759.e6
Mesenchymal stem cell-loaded hydrogel to inhibit inflammatory reaction in surgical brain injury via mitochondria transfer.
Wang Y, Yang X, Liu M, Yan Y, Kong F, Wang J, Zhang Z, Chen Y, Chen L, Liang Z, Peng X, Liu F
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:231-240
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:231-240
WTAP-mediated m(6)A modification of TRIM22 promotes diabetic nephropathy by inducing mitochondrial dysfunction via ubiquitination of OPA1.
Zhang Z, Zhou F, Lu M, Zhang D, Zhang X, Xu S, He Y
Redox report : communications in free radical research 2024 Dec;29(1):2404794
Redox report : communications in free radical research 2024 Dec;29(1):2404794
Regulatory roles of histamine receptor in astrocytic glutamate clearance under conditions of increased glucose variability.
Zhou Y, Xie W, Kong C, Luo W, Wei H, Zheng J
Biochemical pharmacology 2024 Dec;230(Pt 3):116611
Biochemical pharmacology 2024 Dec;230(Pt 3):116611
New TIPARP inhibitor rescues mitochondrial function and brain injury in ischemic stroke.
Cai Y, Gu H, Li L, Liu X, Bai Y, Shen L, Han B, Xu Y, Yao H
Pharmacological research 2024 Dec;210:107508
Pharmacological research 2024 Dec;210:107508
IDH1/MDH1 deacetylation promotes NETosis by regulating OPA1 and autophagy.
Wang Y, Guo J, Zhang D, Shi C, Zhang X, Gong Z
International immunopharmacology 2024 Dec 25;143(Pt 1):113270
International immunopharmacology 2024 Dec 25;143(Pt 1):113270
Aflatoxin B1 Promotes Pyroptosis in IPEC-J2 Cells by Disrupting Mitochondrial Dynamics through the AMPK/NLRP3 Pathway.
Ding J, Cheng X, Zeng C, Zhao Q, Xing C, Zhang C, Cao H, Guo X, Hu G, Zhuang Y
Journal of agricultural and food chemistry 2024 Dec 18;72(50):28093-28108
Journal of agricultural and food chemistry 2024 Dec 18;72(50):28093-28108
Disturbance of mitochondrial dynamics led to spermatogenesis disorder in mice exposed to polystyrene micro- and nanoplastics.
Zhao M, Xie J, Zhang J, Zhao B, Zhang Y, Xue J, Zhang R, Zhang R, Wang H, Li Y, Ge W, Zhou X
Environmental pollution (Barking, Essex : 1987) 2024 Dec 1;362:124935
Environmental pollution (Barking, Essex : 1987) 2024 Dec 1;362:124935
Electroacupuncture improves cognitive impairment after ischemic stroke based on regulation of mitochondrial dynamics through SIRT1/PGC-1α pathway.
Chen L, Chen S, Bai Y, Zhang Y, Li X, Wang Y, Xiao Y, Wan J, Sun K
Brain research 2024 Dec 1;1844:149139
Brain research 2024 Dec 1;1844:149139
Lysosomes drive the piecemeal removal of mitochondrial inner membrane.
Prashar A, Bussi C, Fearns A, Capurro MI, Gao X, Sesaki H, Gutierrez MG, Jones NL
Nature 2024 Aug;632(8027):1110-1117
Nature 2024 Aug;632(8027):1110-1117
Activating MC4R Promotes Functional Recovery by Repressing Oxidative Stress-Mediated AIM2 Activation Post-spinal Cord Injury.
Wang Y, Fang N, Wang Y, Geng Y, Li Y
Molecular neurobiology 2024 Aug;61(8):6101-6118
Molecular neurobiology 2024 Aug;61(8):6101-6118
Icariin Ameliorates D-galactose-induced Cell Injury in Neuron-like PC12 Cells by Inhibiting MPTP Opening.
Hu SS, Wang TY, Ni L, Hu FX, Yue BW, Zheng Y, Wang TL, Kumar A, Wang YY, Wang JE, Zhou ZY
Current medical science 2024 Aug;44(4):748-758
Current medical science 2024 Aug;44(4):748-758
GPRASP2 deficiency contributes to apoptosis in the spiral ganglion cells via the AMPK/DRP1 signaling pathway.
Huang K, Cai J, Lu Y, Wang T, Yue S, Wei Q, Yao J, Chen Z, Cao X
Heliyon 2024 Aug 30;10(16):e36140
Heliyon 2024 Aug 30;10(16):e36140
Pathological characteristics of axons and alterations of proteomic and lipidomic profiles in midbrain dopaminergic neurodegeneration induced by WDR45-deficiency.
Wang P, Shao Y, Al-Nusaif M, Zhang J, Yang H, Yang Y, Kim K, Li S, Liu C, Cai H, Le W
Molecular neurodegeneration 2024 Aug 26;19(1):62
Molecular neurodegeneration 2024 Aug 26;19(1):62
Matrix stiffness aggravates osteoarthritis progression through H3K27me3 demethylation induced by mitochondrial damage.
Kan T, Li H, Hou L, Cui J, Wang Y, Sun L, Wang L, Yan M, Yu Z
iScience 2024 Aug 16;27(8):110507
iScience 2024 Aug 16;27(8):110507
Disturbance of mitochondrial dynamics in myocardium of broilers with pulmonary hypertension syndrome.
Zhang W, Li M, Ye X, Jiang M, Wu X, Tang Z, Hu L, Zhang H, Li Y, Pan J
British poultry science 2024 Apr;65(2):154-164
British poultry science 2024 Apr;65(2):154-164
Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia-reperfusion injury.
Chen X, Yang T, Zhou Y, Mei Z, Zhang W
CNS neuroscience & therapeutics 2024 Apr;30(4):e14725
CNS neuroscience & therapeutics 2024 Apr;30(4):e14725
Schisandrin B Alleviates LPS Induced Mitochondrial Damage in C28I2 Cells.
Hu F, Hu W, Xu H
The Journal of membrane biology 2024 Apr;257(1-2):107-114
The Journal of membrane biology 2024 Apr;257(1-2):107-114
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Wang L, Wang B, Zhang X, Yang Z, Zhang X, Gong H, Song Y, Zhang K, Sun M
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Inhibition of KMO Ameliorates Myocardial Ischemia Injury via Maintaining Mitochondrial Fusion and Fission Balance.
Lai Q, Wu L, Dong S, Zhu X, Fan Z, Kou J, Liu F, Yu B, Li F
International journal of biological sciences 2023;19(10):3077-3098
International journal of biological sciences 2023;19(10):3077-3098
Electroacupuncture Ameliorates Depression-Like Behaviors in Post-Stroke Rats via Activating AMPK-Mediated Mitochondrial Function.
Ding Z, Gao J, Feng Y, Wang M, Zhao H, Wu R, Zheng X, Feng X, Lai M
Neuropsychiatric disease and treatment 2023;19:2657-2671
Neuropsychiatric disease and treatment 2023;19:2657-2671
Shenshuaifu Granule Attenuates Acute Kidney Injury by Inhibiting Ferroptosis Mediated by p53/SLC7A11/GPX4 Pathway.
Jin X, He R, Lin Y, Liu J, Wang Y, Li Z, Liao Y, Yang S
Drug design, development and therapy 2023;17:3363-3383
Drug design, development and therapy 2023;17:3363-3383
Exercise intervention improves mitochondrial quality in non-alcoholic fatty liver disease zebrafish.
Zou YY, Tang XB, Chen ZL, Liu B, Zheng L, Song MY, Xiao Q, Zhou ZQ, Peng XY, Tang CF
Frontiers in endocrinology 2023;14:1162485
Frontiers in endocrinology 2023;14:1162485
Knock-down of YME1L1 induces mitochondrial dysfunction during early porcine embryonic development.
Zhou D, Sun MH, Jiang WJ, Li XH, Lee SH, Heo G, Choi J, Kim KS, Cui XS
Frontiers in cell and developmental biology 2023;11:1147095
Frontiers in cell and developmental biology 2023;11:1147095
Aerobic exercise enhances mitochondrial homeostasis to counteract D-galactose-induced sarcopenia in zebrafish.
Chen ZL, Guo C, Zou YY, Feng C, Yang DX, Sun CC, Wen W, Jian ZJ, Zhao Z, Xiao Q, Zheng L, Peng XY, Zhou ZQ, Tang CF
Experimental gerontology 2023 Sep;180:112265
Experimental gerontology 2023 Sep;180:112265
Mitochondrial miR-12294-5p regulated copper-induced mitochondrial oxidative stress and mitochondrial quality control imbalance by targeted inhibition of CISD1 in chicken livers.
Zhong G, Li Y, Li L, Huo Y, Zhang W, Li T, Ma F, Liao J, Li Y, Zhang H, Guo J, Pan J, Yu W, Hu L, Tang Z
Journal of hazardous materials 2023 Sep 15;458:131908
Journal of hazardous materials 2023 Sep 15;458:131908
DMT1 differentially regulates mitochondrial complex activities to reduce glutathione loss and mitigate ferroptosis.
Tan Q, Zhang X, Li S, Liu W, Yan J, Wang S, Cui F, Li D, Li J
Free radical biology & medicine 2023 Oct;207:32-44
Free radical biology & medicine 2023 Oct;207:32-44
Polydatin improves vascular endothelial function by maintaining mitochondrial homeostasis under high glucose conditions.
Shah W, Zhao Q, Wang S, Zhang M, Ma H, Guan Y, Zhang Y, Liu Y, Zhu C, Wang S, Zhang X, Dong J, Ma H
Scientific reports 2023 Oct 2;13(1):16550
Scientific reports 2023 Oct 2;13(1):16550
Down-regulation of the mitochondrial fusion protein Opa1/Mfn2 promotes cardiomyocyte hypertrophy in Su5416/hypoxia-induced pulmonary hypertension rats.
Luo F, Fu M, Wang T, Qi Y, Zhong X, Li D, Liu B
Archives of biochemistry and biophysics 2023 Oct 1;747:109743
Archives of biochemistry and biophysics 2023 Oct 1;747:109743
AdipoRon mitigates tau pathology and restores mitochondrial dynamics via AMPK-related pathway in a mouse model of Alzheimer's disease.
Wang C, Chang Y, Zhu J, Wu Y, Jiang X, Zheng S, Li G, Ma R
Experimental neurology 2023 May;363:114355
Experimental neurology 2023 May;363:114355
High uric acid aggravates apoptosis of lung epithelial cells induced by cigarette smoke extract through downregulating PRDX2 in chronic obstructive pulmonary disease.
Dong Y, Han F, Su Y, Sun B, Zhao W, Pan C
International immunopharmacology 2023 May;118:110056
International immunopharmacology 2023 May;118:110056
QiShenYiQi dripping pill alleviates myocardial ischemia-induced ferroptosis via improving mitochondrial dynamical homeostasis and biogenesis.
Wu L, Fan Z, Gu L, Liu J, Cui Z, Yu B, Kou J, Li F
Journal of ethnopharmacology 2023 May 23;308:116282
Journal of ethnopharmacology 2023 May 23;308:116282
SZC-6, a small-molecule activator of SIRT3, attenuates cardiac hypertrophy in mice.
Li ZY, Lu GQ, Lu J, Wang PX, Zhang XL, Zou Y, Liu PQ
Acta pharmacologica Sinica 2023 Mar;44(3):546-560
Acta pharmacologica Sinica 2023 Mar;44(3):546-560
Long-term blue light exposure impairs mitochondrial dynamics in the retina in light-induced retinal degeneration in vivo and in vitro.
Wang L, Yu X, Zhang D, Wen Y, Zhang L, Xia Y, Chen J, Xie C, Zhu H, Tong J, Shen Y
Journal of photochemistry and photobiology. B, Biology 2023 Mar;240:112654
Journal of photochemistry and photobiology. B, Biology 2023 Mar;240:112654
NSC228155 alleviates septic cardiomyopathy via protecting mitochondria and inhibiting inflammation.
Jiang Y, Li Y, Zhang Y, Hu D, Zhang S, Wang C, Huang S, Zhang A, Jia Z, You R
International immunopharmacology 2023 Mar;116:109847
International immunopharmacology 2023 Mar;116:109847
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
Chen L, Mao M, Liu D, Liu W, Wang Y, Xie L, Deng Y, Lin Y, Xu Y, Zhong X, Cao W
International immunopharmacology 2023 Mar;116:109648
International immunopharmacology 2023 Mar;116:109648
Empagliflozin ameliorates cardiac dysfunction in heart failure mice via regulating mitochondrial dynamics.
Lyu Y, Huo J, Jiang W, Yang W, Wang S, Zhang S, Cheng Y, Jiang Z, Shan Q
European journal of pharmacology 2023 Mar 5;942:175531
European journal of pharmacology 2023 Mar 5;942:175531
Proteomic Characterization of Peritoneal Extracellular Vesicles in a Mouse Model of Peritoneal Fibrosis.
Huang Q, Sun Y, Sun J, Peng L, Shang H, Wei D, Li C, Hu Z, Peng H
Journal of proteome research 2023 Mar 3;22(3):908-918
Journal of proteome research 2023 Mar 3;22(3):908-918
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury.
Zhang J, Zhang M, Huo XK, Ning J, Yu ZL, Morisseau C, Sun CP, Hammock BD, Ma XC
ACS central science 2023 Mar 22;9(3):440-456
ACS central science 2023 Mar 22;9(3):440-456
MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model.
Shahin S, Lu B, Zhou Y, Xu H, Chetsawang J, Baloh RH, Wang S
iScience 2023 Mar 17;26(3):106270
iScience 2023 Mar 17;26(3):106270
Dexpramipexole ameliorates cognitive deficits in sepsis-associated encephalopathy through suppressing mitochondria-mediated pyroptosis and apoptosis.
Zhang Y, Fu Q, Ruan J, Shi C, Lu W, Wu J, Zhou Z
Neuroreport 2023 Mar 1;34(4):220-231
Neuroreport 2023 Mar 1;34(4):220-231
Pseudolaric acid B triggers cell apoptosis by activating AMPK/JNK/DRP1/mitochondrial fission pathway in hepatocellular carcinoma.
Liu Z, Wang N, Meng Z, Lu S, Peng G
Toxicology 2023 Jul;493:153556
Toxicology 2023 Jul;493:153556
Identification of mitochondrial related signature associated with immune microenvironment in Alzheimer's disease.
Zhang Y, Miao Y, Tan J, Chen F, Lei P, Zhang Q
Journal of translational medicine 2023 Jul 11;21(1):458
Journal of translational medicine 2023 Jul 11;21(1):458
N-acetyl-L-cysteine alleviates FUNDC1-mediated mitophagy by regulating mitochondrial dynamics in type 1 diabetic nephropathy canine.
Ma F, Li H, Huo H, Han Q, Liao J, Zhang H, Li Y, Pan J, Hu L, Guo J, Tang Z
Life sciences 2023 Jan 15;313:121278
Life sciences 2023 Jan 15;313:121278
Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis.
Zhou Y, Tang J, Lan J, Zhang Y, Wang H, Chen Q, Kang Y, Sun Y, Feng X, Wu L, Jin H, Chen S, Peng Y
Acta pharmaceutica Sinica. B 2023 Feb;13(2):577-597
Acta pharmaceutica Sinica. B 2023 Feb;13(2):577-597
A quantitative proteomic analyses of primary myocardial cell injury induced by heat stress in chicken embryo.
Wang R, Guo Y, Shi Z, Qin S
Journal of thermal biology 2023 Feb;112:103461
Journal of thermal biology 2023 Feb;112:103461
CoLoC-seq probes the global topology of organelle transcriptomes.
Jeandard D, Smirnova A, Fasemore AM, Coudray L, Entelis N, Förstner KU, Tarassov I, Smirnov A
Nucleic acids research 2023 Feb 22;51(3):e16
Nucleic acids research 2023 Feb 22;51(3):e16
Selenium alleviates cadmium-induced mitophagy through FUNDC1-mediated mitochondrial quality control pathway in the lungs of sheep.
Lin S, Yang F, Hu M, Chen J, Chen G, Hu A, Li X, Fu D, Xing C, Xiong Z, Wu Y, Cao H
Environmental pollution (Barking, Essex : 1987) 2023 Feb 15;319:120954
Environmental pollution (Barking, Essex : 1987) 2023 Feb 15;319:120954
SIRT3 promotes metabolic maturation of human iPSC-derived cardiomyocytes via OPA1-controlled mitochondrial dynamics.
Wang R, Xu H, Tan B, Yi Q, Sun Y, Xiang H, Chen T, Liu H, Xie Q, Wang L, Tian J, Zhu J
Free radical biology & medicine 2023 Feb 1;195:270-282
Free radical biology & medicine 2023 Feb 1;195:270-282
Saponins from Panax japonicus improve neuronal mitochondrial injury of aging rats.
Fan C, Wang JX, Xiong ZE, Hu SS, Zhou AJ, Yuan D, Zhang CC, Zhou ZY, Wang T
Pharmaceutical biology 2023 Dec;61(1):1401-1412
Pharmaceutical biology 2023 Dec;61(1):1401-1412
Effects of propranolol on glucose metabolism in hemangioma-derived endothelial cells.
Yang K, Li X, Qiu T, Zhou J, Gong X, Lan Y, Ji Y
Biochemical pharmacology 2023 Dec;218:115922
Biochemical pharmacology 2023 Dec;218:115922
Proteomic analysis reveals the aging-related pathways contribute to pulmonary fibrogenesis.
Zhang T, Yuan X, Jiang M, Liu B, Zhai N, Zhang Q, Song X, Lv C, Zhang J, Li H
Aging 2023 Dec 22;15(24):15382-15401
Aging 2023 Dec 22;15(24):15382-15401
Diosgenin Targets CaMKK2 to Alleviate Type II Diabetic Nephropathy through Improving Autophagy, Mitophagy and Mitochondrial Dynamics.
Zhong Y, Jin R, Luo R, Liu J, Ren L, Zhang Y, Shan Z, Peng X
Nutrients 2023 Aug 11;15(16)
Nutrients 2023 Aug 11;15(16)
Ginsenoside Rg1 protects cardiac mitochondrial function via targeting GSTP1 to block S-glutathionylation of optic atrophy 1.
Zhu H, Yan C, Yao P, Li P, Li Y, Yang H
Free radical biology & medicine 2023 Aug 1;204:54-67
Free radical biology & medicine 2023 Aug 1;204:54-67
Mitochondrial division inhibitor (mdivi-1) inhibits proliferation and epithelial-mesenchymal transition via the NF-κB pathway in thyroid cancer cells.
Zhang L, Sun L, Wang L, Wang J, Wang D, Jiang J, Zhang J, Zhou Q
Toxicology in vitro : an international journal published in association with BIBRA 2023 Apr;88:105552
Toxicology in vitro : an international journal published in association with BIBRA 2023 Apr;88:105552
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
Qiu S, Zhong X, Meng X, Li S, Qian X, Lu H, Cai J, Zhang Y, Wang M, Ye Z, Zhang H, Gao P
Cell research 2023 Apr;33(4):299-311
Cell research 2023 Apr;33(4):299-311
Mitofilin Heterozygote Mice Display an Increase in Myocardial Injury and Inflammation after Ischemia/Reperfusion.
Feng Y, Imam Aliagan A, Tombo N, Bopassa JC
Antioxidants (Basel, Switzerland) 2023 Apr 13;12(4)
Antioxidants (Basel, Switzerland) 2023 Apr 13;12(4)
HIGD2A silencing impairs hepatocellular carcinoma growth via inhibiting mitochondrial function and the MAPK/ERK pathway.
Huang K, Liu Z, Xie Z, Li X, Zhang H, Chen Y, Wang Y, Lin Z, Li C, Liu H, Zhang X
Journal of translational medicine 2023 Apr 12;21(1):253
Journal of translational medicine 2023 Apr 12;21(1):253
Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2.
Wang P, Zhang S, Liu W, Chen S, Lv X, Hu B, Shao Z
Oxidative medicine and cellular longevity 2022;2022:7531788
Oxidative medicine and cellular longevity 2022;2022:7531788
Combination of Perindopril Erbumine and Huangqi-Danshen Decoction Protects Against Chronic Kidney Disease via Sirtuin3/Mitochondrial Dynamics Pathway.
Wei X, Wang Y, Weng J, Lao Y, Deng R, Lu J, Yang S, Liu X
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5812105
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5812105
COA3 overexpression promotes non-small cell lung cancer metastasis by reprogramming glucose metabolism.
Lin H, Gao Y, Sun K, Zhang Q, Li Y, Chen M, Jin F
American journal of cancer research 2022;12(8):3662-3678
American journal of cancer research 2022;12(8):3662-3678
Battery wastewater induces nephrotoxicity via disordering the mitochondrial dynamics.
Yi J, Liao J, Bai T, Wang B, Yangzom C, Ahmed Z, Mehmood K, Abbas RZ, Li Y, Tang Z, Zhang H
Chemosphere 2022 Sep;303(Pt 1):135018
Chemosphere 2022 Sep;303(Pt 1):135018
CERKL, a Retinal Dystrophy Gene, Regulates Mitochondrial Transport and Dynamics in Hippocampal Neurons.
García-Arroyo R, Marfany G, Mirra S
International journal of molecular sciences 2022 Sep 30;23(19)
International journal of molecular sciences 2022 Sep 30;23(19)
Senescent Phenotype of Astrocytes Leads to Activation of BV2 Microglia and N2a Neuronal Cells Death.
Zhang W, Yang X, Liu J, Pan Y, Zhang M, Chen L
Molecules (Basel, Switzerland) 2022 Sep 12;27(18)
Molecules (Basel, Switzerland) 2022 Sep 12;27(18)
Blocking exosomal secretion aggravates 1,4-benzoquinone-induced mitochondrial fission activated by the AMPK/MFF/Drp1 pathway in HL-60 cells.
Lu F, Zhang Q, Zhang M, Sun S, Yang X, Yan H
Journal of applied toxicology : JAT 2022 Oct;42(10):1618-1627
Journal of applied toxicology : JAT 2022 Oct;42(10):1618-1627
Protective Effect of Manganese on Apoptosis and Mitochondrial Function of Heat-Stressed Primary Chick Embryonic Myocardial Cells.
Wang R, Shi Z, Li J, Tang D, Qin S, Guo Y
Biological trace element research 2022 Oct;200(10):4419-4429
Biological trace element research 2022 Oct;200(10):4419-4429
Omentin1 ameliorates myocardial ischemia-induced heart failure via SIRT3/FOXO3a-dependent mitochondrial dynamical homeostasis and mitophagy.
Hu J, Liu T, Fu F, Cui Z, Lai Q, Zhang Y, Yu B, Liu F, Kou J, Li F
Journal of translational medicine 2022 Oct 4;20(1):447
Journal of translational medicine 2022 Oct 4;20(1):447
Integrated Analysis of Transcriptome and microRNA Profile Reveals the Toxicity of Euphorbia Factors toward Human Colon Adenocarcinoma Cell Line Caco-2.
Zou L, Bao W, Gao Y, Chen M, Wu Y, Wang S, Li C, Zhang J, Zhang D, Wang Q, Zhu A
Molecules (Basel, Switzerland) 2022 Oct 16;27(20)
Molecules (Basel, Switzerland) 2022 Oct 16;27(20)
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
Lan B, Zhao H, He Y, Zhao Z, Wang N, Gao Y
Experimental cell research 2022 Nov 15;420(2):113358
Experimental cell research 2022 Nov 15;420(2):113358
SIRT4 Expression Ameliorates the Detrimental Effect of Heat Stress via AMPK/mTOR Signaling Pathway in BMECs.
Ding Q, Wang Y, Xia SW, Zhao F, Zhong JF, Wang HL, Chen KL
International journal of molecular sciences 2022 Nov 1;23(21)
International journal of molecular sciences 2022 Nov 1;23(21)
A High-Fat Diet Induces Muscle Mitochondrial Dysfunction and Impairs Swimming Capacity in Zebrafish: A New Model of Sarcopenic Obesity.
Zou YY, Chen ZL, Sun CC, Yang D, Zhou ZQ, Xiao Q, Peng XY, Tang CF
Nutrients 2022 May 9;14(9)
Nutrients 2022 May 9;14(9)
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.
Jiang B, Zhang J, Zhao G, Liu M, Hu J, Lin F, Wang J, Zhao W, Ma H, Zhang C, Wu C, Yao L, Liu Q, Chen X, Cao Y, Zheng Y, Zhang C, Han A, Lin D, Li Q
Molecular cell 2022 May 19;82(10):1821-1835.e6
Molecular cell 2022 May 19;82(10):1821-1835.e6
HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3.
Hu B, Wang P, Zhang S, Liu W, Lv X, Shi D, Zhao L, Liu H, Wang B, Chen S, Shao Z
Experimental & molecular medicine 2022 Mar;54(3):309-323
Experimental & molecular medicine 2022 Mar;54(3):309-323
Environmental cadmium impairs blood-testis barrier via activating HRI-responsive mitochondrial stress in mice.
Zhou GX, Liu WB, Dai LM, Zhu HL, Xiong YW, Li DX, Xu DX, Wang H
The Science of the total environment 2022 Mar 1;810:152247
The Science of the total environment 2022 Mar 1;810:152247
Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.
Li Y, Yang L, Hu F, Xu J, Ye J, Liu S, Wang L, Zhuo M, Ran B, Zhang H, Ye J, Xiao J
ACS applied materials & interfaces 2022 Jun 8;14(22):25155-25172
ACS applied materials & interfaces 2022 Jun 8;14(22):25155-25172
Selenium alleviates cadmium-induced aging via mitochondrial quality control in the livers of sheep.
Xiong Z, Yang F, Xu T, Yang Y, Wang F, Zhou G, Wang Q, Guo X, Xing C, Bai H, Chen J, Wu Y, Yang S, Cao H
Journal of inorganic biochemistry 2022 Jul;232:111818
Journal of inorganic biochemistry 2022 Jul;232:111818
The Mitochondrial PHB2/OMA1/DELE1 Pathway Cooperates with Endoplasmic Reticulum Stress to Facilitate the Response to Chemotherapeutics in Ovarian Cancer.
Cheng M, Yu H, Kong Q, Wang B, Shen L, Dong D, Sun L
International journal of molecular sciences 2022 Jan 25;23(3)
International journal of molecular sciences 2022 Jan 25;23(3)
Herceptin induces ferroptosis and mitochondrial dysfunction in H9c2 cells.
Sun L, Wang H, Yu S, Zhang L, Jiang J, Zhou Q
International journal of molecular medicine 2022 Feb;49(2)
International journal of molecular medicine 2022 Feb;49(2)
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
Wang N, Huang R, Yang K, He Y, Gao Y, Dong D
Journal of cellular and molecular medicine 2022 Feb;26(3):893-912
Journal of cellular and molecular medicine 2022 Feb;26(3):893-912
Cdk5 Promotes Mitochondrial Fission via Drp1 Phosphorylation at S616 in Chronic Ethanol Exposure-Induced Cognitive Impairment.
Liu D, Li J, Rong X, Li J, Peng Y, Shen Q
Molecular neurobiology 2022 Dec;59(12):7075-7094
Molecular neurobiology 2022 Dec;59(12):7075-7094
Activation of FMS-like tyrosine kinase 3 protects against isoprenaline-induced cardiac hypertrophy by improving autophagy and mitochondrial dynamics.
Jiang X, Zhang K, Gao C, Ma W, Liu M, Guo X, Bao G, Han B, Hu H, Zhao Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Dec;36(12):e22672
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Dec;36(12):e22672
CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer's disease.
Xie W, Guo D, Li J, Yue L, Kang Q, Chen G, Zhou T, Wang H, Zhuang K, Leng L, Li H, Chen Z, Gao W, Zhang J
Cell death and differentiation 2022 Dec;29(12):2417-2428
Cell death and differentiation 2022 Dec;29(12):2417-2428
GABA regulates IL-1β production in macrophages.
Fu J, Han Z, Wu Z, Xia Y, Yang G, Yin Y, Ren W
Cell reports 2022 Dec 6;41(10):111770
Cell reports 2022 Dec 6;41(10):111770
Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function.
Jang W, Puchkov D, Samsó P, Liang Y, Nadler-Holly M, Sigrist SJ, Kintscher U, Liu F, Mamchaoui K, Mouly V, Haucke V
Science (New York, N.Y.) 2022 Dec 16;378(6625):eabq5209
Science (New York, N.Y.) 2022 Dec 16;378(6625):eabq5209
Protective Effect and Mechanism of Melatonin on Cisplatin-Induced Ovarian Damage in Mice.
Xing F, Wang M, Ding Z, Zhang J, Ding S, Shi L, Xie Q, Ahmad MJ, Wei Z, Tang L, Liang D, Cao Y, Liu Y
Journal of clinical medicine 2022 Dec 12;11(24)
Journal of clinical medicine 2022 Dec 12;11(24)
A pivotal role of selective autophagy in mitochondrial quality control: Implications for zinc oxide nanoparticles induced neurotoxicity.
Wang L, Duan Z, Liang M, Wang C, Liang T, Sun L, Yan C, Li Q, Liang T
Chemico-biological interactions 2022 Aug 25;363:110003
Chemico-biological interactions 2022 Aug 25;363:110003
Phosphorylation of Dynamin-Related Protein 1 (DRP1) Regulates Mitochondrial Dynamics and Skeletal Muscle Wasting in Cancer Cachexia.
Mao X, Gu Y, Sui X, Shen L, Han J, Wang H, Xi Q, Zhuang Q, Meng Q, Wu G
Frontiers in cell and developmental biology 2021;9:673618
Frontiers in cell and developmental biology 2021;9:673618
Mitochondrial Fusion Potentially Regulates a Metabolic Change in Tibetan Chicken Embryonic Brain During Hypoxia.
Tang Q, Ding C, Xu Q, Bai Y, Xu Q, Wang K, Fang M
Frontiers in cell and developmental biology 2021;9:585166
Frontiers in cell and developmental biology 2021;9:585166
Mitochondrial-Targeting Antioxidant SS-31 Suppresses Airway Inflammation and Oxidative Stress Induced by Cigarette Smoke.
Yang DQ, Zuo QN, Wang T, Xu D, Lian L, Gao LJ, Wan C, Chen L, Wen FQ, Shen YC
Oxidative medicine and cellular longevity 2021;2021:6644238
Oxidative medicine and cellular longevity 2021;2021:6644238
RNA-Seq Profiling to Investigate the Mechanism of Qishen Granules on Regulating Mitochondrial Energy Metabolism of Heart Failure in Rats.
He H, Li C, Lu X, Li Y, Li X, Sun X, Tang B, Wu Y, Li C
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5779307
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5779307
Mitochondrial Transplantation Attenuates Cerebral Ischemia-Reperfusion Injury: Possible Involvement of Mitochondrial Component Separation.
Xie Q, Zeng J, Zheng Y, Li T, Ren J, Chen K, Zhang Q, Xie R, Xu F, Zhu J
Oxidative medicine and cellular longevity 2021;2021:1006636
Oxidative medicine and cellular longevity 2021;2021:1006636
Tortoise Plastron and Deer Antler Gelatin Prevents Against Neuronal Mitochondrial Dysfunction In Vitro: Implication for a Potential Therapy of Alzheimer's Disease.
Cheng D, Yang XJ, Zhang L, Qin ZS, Li WQ, Xu HC, Zhang ZJ
Frontiers in pharmacology 2021;12:690256
Frontiers in pharmacology 2021;12:690256
MicroRNA-214 contributes to Ang II-induced cardiac hypertrophy by targeting SIRT3 to provoke mitochondrial malfunction.
Ding YQ, Zhang YH, Lu J, Li B, Yu WJ, Yue ZB, Hu YH, Wang PX, Li JY, Cai SD, Ye JT, Liu PQ
Acta pharmacologica Sinica 2021 Sep;42(9):1422-1436
Acta pharmacologica Sinica 2021 Sep;42(9):1422-1436
Jian-Pi-Yi-Shen formula enhances perindopril inhibition of chronic kidney disease progression by activation of SIRT3, modulation of mitochondrial dynamics, and antioxidant effects.
Liu X, Deng R, Wei X, Wang Y, Weng J, Lao Y, Lu J, Xiong G, Li S
Bioscience reports 2021 Oct 29;41(10)
Bioscience reports 2021 Oct 29;41(10)
Melatonin protects against excessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells.
Xie QE, Wang MY, Cao ZP, Du X, Ji DM, Liang D, Cao YX, Liu YJ
Mitochondrion 2021 Nov;61:44-53
Mitochondrion 2021 Nov;61:44-53
Moderate mechanical stress suppresses the IL-1β-induced chondrocyte apoptosis by regulating mitochondrial dynamics.
Zhang J, Hao X, Chi R, Qi J, Xu T
Journal of cellular physiology 2021 Nov;236(11):7504-7515
Journal of cellular physiology 2021 Nov;236(11):7504-7515
Trib1 deficiency causes brown adipose respiratory chain depletion and mitochondrial disorder.
Zhang X, Zhang B, Zhang C, Sun G, Sun X
Cell death & disease 2021 Nov 22;12(12):1098
Cell death & disease 2021 Nov 22;12(12):1098
LACTB suppresses melanoma progression by attenuating PP1A and YAP interaction.
Ma Y, Wang L, He F, Yang J, Ding Y, Ge S, Fan X, Zhou Y, Xu X, Jia R
Cancer letters 2021 May 28;506:67-82
Cancer letters 2021 May 28;506:67-82
Levosimendan in rats decreases acute kidney injury after cardiopulmonary resuscitation by improving mitochondrial dysfunction.
Zhao L, Tian L, Wang S, Yang W, Lu X, Zhu C
Translational andrology and urology 2021 Jul;10(7):3010-3020
Translational andrology and urology 2021 Jul;10(7):3010-3020
CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson's disease.
Hu Z, Mao C, Wang H, Zhang Z, Zhang S, Luo H, Tang M, Yang J, Yuan Y, Wang Y, Liu Y, Fan L, Zhang Q, Yao D, Liu F, Schisler JC, Shi C, Xu Y
Aging 2021 Jan 2;13(1):1458-1472
Aging 2021 Jan 2;13(1):1458-1472
The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
Khodayari N, Wang RL, Oshins R, Lu Y, Millett M, Aranyos AM, Mostofizadeh S, Scindia Y, Flagg TO, Brantly M
International journal of molecular sciences 2021 Dec 9;22(24)
International journal of molecular sciences 2021 Dec 9;22(24)
Chronic hypoxia alters cardiac mitochondrial complex protein expression and activity in fetal guinea pigs in a sex-selective manner.
Song H, Polster BM, Thompson LP
American journal of physiology. Regulatory, integrative and comparative physiology 2021 Dec 1;321(6):R912-R924
American journal of physiology. Regulatory, integrative and comparative physiology 2021 Dec 1;321(6):R912-R924
CERKL, a retinal dystrophy gene, regulates mitochondrial function and dynamics in the mammalian retina.
Mirra S, García-Arroyo R, B Domènech E, Gavaldà-Navarro A, Herrera-Úbeda C, Oliva C, Garcia-Fernàndez J, Artuch R, Villarroya F, Marfany G
Neurobiology of disease 2021 Aug;156:105405
Neurobiology of disease 2021 Aug;156:105405
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
Deng X, Liu J, Liu L, Sun X, Huang J, Dong J
International journal of biological sciences 2020;16(8):1403-1416
International journal of biological sciences 2020;16(8):1403-1416
Inhibition of Cathepsin S Induces Mitochondrial Apoptosis in Glioblastoma Cell Lines Through Mitochondrial Stress and Autophagosome Accumulation.
Fei M, Zhang L, Wang H, Zhu Y, Niu W, Tang T, Han Y
Frontiers in oncology 2020;10:516746
Frontiers in oncology 2020;10:516746
Lamprey PHB2 maintains mitochondrial stability by tanslocation to the mitochondria under oxidative stress.
Shi Y, Li Q, Sun F, Zhu C, Ma S, Qin D, Li Q, Li T
Fish & shellfish immunology 2020 Sep;104:613-621
Fish & shellfish immunology 2020 Sep;104:613-621
PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth.
Guo L, Cui C, Wang J, Yuan J, Yang Q, Zhang P, Su W, Bao R, Ran J, Wu C
Nature communications 2020 Oct 1;11(1):4913
Nature communications 2020 Oct 1;11(1):4913
circ-CBFB upregulates p66Shc to perturb mitochondrial dynamics in APAP-induced liver injury.
Wang Z, Zhao Y, Sun R, Sun Y, Liu D, Lin M, Chen Z, Zhou J, Lv L, Tian X, Yao J
Cell death & disease 2020 Nov 6;11(11):953
Cell death & disease 2020 Nov 6;11(11):953
AIM2 promotes the development of non-small cell lung cancer by modulating mitochondrial dynamics.
Qi M, Dai D, Liu J, Li Z, Liang P, Wang Y, Cheng L, Zhan Y, An Z, Song Y, Yang Y, Yan X, Xiao H, Shao H
Oncogene 2020 Mar;39(13):2707-2723
Oncogene 2020 Mar;39(13):2707-2723
Lactate accelerates vascular calcification through NR4A1-regulated mitochondrial fission and BNIP3-related mitophagy.
Zhu Y, Han XQ, Sun XJ, Yang R, Ma WQ, Liu NF
Apoptosis : an international journal on programmed cell death 2020 Jun;25(5-6):321-340
Apoptosis : an international journal on programmed cell death 2020 Jun;25(5-6):321-340
Silibinin inhibits migration and invasion of breast cancer MDA-MB-231 cells through induction of mitochondrial fusion.
Si L, Fu J, Liu W, Hayashi T, Nie Y, Mizuno K, Hattori S, Fujisaki H, Onodera S, Ikejima T
Molecular and cellular biochemistry 2020 Jan;463(1-2):189-201
Molecular and cellular biochemistry 2020 Jan;463(1-2):189-201
Fluoride-induced renal dysfunction via respiratory chain complex abnormal expression and fusion elevation in mice.
Wang HW, Zhu SQ, Liu J, Miao CY, Zhang Y, Zhou BH
Chemosphere 2020 Jan;238:124607
Chemosphere 2020 Jan;238:124607
Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice.
Wang HW, Liu J, Wei SS, Zhao WP, Zhu SQ, Zhou BH
Chemosphere 2020 Feb;241:125099
Chemosphere 2020 Feb;241:125099
Sodium-glucose cotransporter 2 inhibition attenuates protein overload in renal proximal tubule via suppression of megalin O-GlcNacylation in progressive diabetic nephropathy.
Otomo H, Nara M, Kato S, Shimizu T, Suganuma Y, Sato T, Morii T, Yamada Y, Fujita H
Metabolism: clinical and experimental 2020 Dec;113:154405
Metabolism: clinical and experimental 2020 Dec;113:154405
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
Ma D, Zheng B, Liu HL, Zhao YB, Liu X, Zhang XH, Li Q, Shi WB, Suzuki T, Wen JK
PLoS biology 2020 Aug;18(8):e3000808
PLoS biology 2020 Aug;18(8):e3000808
Mitochondrial unfolded protein response gene CLPP changes mitochondrial dynamics and affects mitochondrial function.
Wu G, Xiong Q, Wei X, Wang Y, Hu X, He G, Liu L, Lai Q, Dai Z, Anushesh D, Xu Y
PeerJ 2019;7:e7209
PeerJ 2019;7:e7209
Mitofusin 2 is involved in chemotaxis of neutrophil-like differentiated HL-60 cells.
Mazaki Y, Takada S, Nio-Kobayashi J, Maekawa S, Higashi T, Onodera Y, Sabe H
Biochemical and biophysical research communications 2019 Jun 4;513(3):708-713
Biochemical and biophysical research communications 2019 Jun 4;513(3):708-713
Arsenic-induced cardiotoxicity correlates with mitochondrial damage and trace elements imbalance in broiler chickens.
Li S, Zhao H, Wang Y, Shao Y, Liu J, Xing M
Poultry science 2019 Feb 1;98(2):734-744
Poultry science 2019 Feb 1;98(2):734-744
Silibinin-induced apoptosis of breast cancer cells involves mitochondrial impairment.
Si L, Liu W, Hayashi T, Ji Y, Fu J, Nie Y, Mizuno K, Hattori S, Onodera S, Ikejima T
Archives of biochemistry and biophysics 2019 Aug 15;671:42-51
Archives of biochemistry and biophysics 2019 Aug 15;671:42-51
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Li S, Zhao H, Wang Y, Shao Y, Li J, Liu J, Xing M
Chemosphere 2017 Dec;189:489-497
Chemosphere 2017 Dec;189:489-497
Antagonistic effects of selenium on cadmium-induced apoptosis by restoring the mitochondrial dynamic equilibrium and energy metabolism in chicken spleens.
Xu Z, Jin X, Pan T, Liu T, Wan N, Li S
Oncotarget 2017 Aug 8;8(32):52629-52641
Oncotarget 2017 Aug 8;8(32):52629-52641
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