Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 358106 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#358106, RRID:AB_2562579
- Product name
- PE/Cy7 anti-human B7-H4
- Antibody type
- Monoclonal
- Antigen
- 0
- Description
- B7-H4, also known as VTCN1, is a type I transmembrane protein and member of the B7 family. Its extracellular region consists of one IgV-like and one IgC-like domain. B7-H4 expression has been reported on activated T cells, B cells, monocytes, and dendritic cells. On T cells, B7-H4 inhibits proliferation, cytokine secretion, and cytotoxicity. B7-H4 is also expressed by different carcinomas including renal, gastric, breast, ovarian and melanoma. Its expression is associated with a poor prognosis.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Antibody clone number
- MIH43
- Vial size
- 100 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
No comments: Submit comment
Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- Human B7-H4 transfected cells were stained with B7-H4 (clone MIH43) PE/Cy7 (filled histogram) or mouse IgG1, κ PE/Cy7 isotype control (open histogram).
- Conjugate
- Near infrared dye