RA0818

antibody from Oursmab

Targeting: VTCN1 B7-H4, B7H4, B7S1, B7x, FLJ22418

Western blot (Data presented on provider website)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0818

Provider

Oursmab

Product name

Puxitatug (Biosimilar Reference Antibody) (VTCN1)

Antibody type

Monoclonal

Description

Puxitatug Samrotecan is an antibody-drug conjugate (ADC) developed by AstraZeneca. It consists of an antibody targeting the B7-H4 protein on cancer cells, linked to the cytotoxic payload Samrotecan, a topoisomerase I inhibitor. Upon binding to B7-H4, the ADC is internalized, releasing the payload to cause DNA damage and inhibit tumor cell replication. It is under evaluation for advanced solid tumors such as breast and endometrial cancer.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.