RA0469

antibody from Oursmab

Targeting: LRRC15 LIB

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0469

Provider

Oursmab

Product name

Samrotamab (Biosimilar Reference Antibody) (LRRC15)

Antibody type

Monoclonal

Description

Samrotamab is a chimeric human-mouse IgG1 kappa monoclonal antibody targeting leucine-rich repeat-containing protein 15 (LRRC15), a transmembrane protein highly expressed in the stroma of various solid tumors (e.g., sarcoma, pancreatic cancer, glioblastoma). By binding to LRRC15 on cancer-associated fibroblasts and some tumor cells, it aims to disrupt tumor-stroma interactions, inhibit tumor progression, and potentially deliver cytotoxic effects via antibody-dependent cellular cytotoxicity (ADCC).

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Samrotamab (Biosimilar Reference Antibody) (LRRC15)-RA0469-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.