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- Antigen structure
- References [22]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 15516-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15516-1-AP, RRID:AB_2120111
- Product name
- HSD3B2 antibody
- Antibody type
- Polyclonal
- Description
- HSD3B2 antibody (Cat. #15516-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Melatonin orchestrates cAMP-PKA signaling to alleviate zearalenone-impaired the estradiol synthesis in mammal ovary.
Zinc Alleviates Oxidative Stress Injury of the Testis Induced by Zearalenone through Sirt3-Foxo3 Pathway in Mice.
NMN/NAD(+)/SIRT1 axis activates NAMPT to ameliorate H(2)O(2)-triggered the impairment of progesterone synthesis in ovarian granulosa cells.
Arsenic exposure reduces testosterone synthesis partially by evoking Leydig cell ferroptosis in mouse testes.
Zhuling Yanzong formula ameliorates obesity-induced oligoasthenozoospermia via regulating HSL/StAR and HSL/TIMP-1.
Saffron extract alleviates D-gal-induced late-onset hypogonadism by activating the PI3K-Akt-Nrf2 signaling pathway.
Characterization of Metabolic Patterns in Mouse Spermatogenesis and Its Clinical Implications in Humans.
The Role of Primary Cilia in Modulating the Luteinization Process of Ovarian Granulosa Cells in Mice.
DEHP-mediated oxidative stress leads to impaired testosterone synthesis in Leydig cells through the cAMP/PKA/SF-1/StAR pathway.
Gut-ovary axis and multiomic insights into PCOS in a DHEA-induced rat model.
Bioactive Peptide C248 of PRDX4 Ameliorates the Function of Testicular Leydig Cells via Mitochondrial Protection.
α-GalCer regulates acute stress-induced steroidogenesis by modulating lipid metabolism in female BALB/c mice.
The downregulation of hormone-sensitive lipase and dysregulation of cholesterol receptors/transporter affect testicular lipid homeostasis and function in HFD-induced oligoasthenospermia mice.
Ti(3)C(2) nanosheet-induced autophagy derails ovarian functions.
Exploring the mechanism of carbamazepine decreasing testosterone levels based on cAMP/PKA/CREB pathway.
Tributyltin chloride (TBTCL) induces cell injury via dysregulation of endoplasmic reticulum stress and autophagy in Leydig cells.
Long-Term Maintenance and Meiotic Entry of Early Germ Cells in Murine Testicular Organoids Functionalized by 3D Printed Scaffolds and Air-Medium Interface Cultivation.
Cushing's syndrome caused by intra-adrenocortical adrenocorticotropic hormone in a dog.
Generation and characteristics of human Sertoli cell line immortalized by overexpression of human telomerase.
A Dietary Medium-Chain Fatty Acid, Decanoic Acid, Inhibits Recruitment of Nur77 to the HSD3B2 Promoter In Vitro and Reverses Endocrine and Metabolic Abnormalities in a Rat Model of Polycystic Ovary Syndrome.
Ectopic cortisol-producing adrenocortical adenoma in the renal hilum: histopathological features and steroidogenic enzyme profile.
Brain-derived neurotrophic factor expression in granulosa lutein cells.
Li Q, Li T, Wang Y, Li Y, Wang S, Lan D, Li J, Fu W
International immunopharmacology 2026 Jun 15;179:116585
International immunopharmacology 2026 Jun 15;179:116585
Zinc Alleviates Oxidative Stress Injury of the Testis Induced by Zearalenone through Sirt3-Foxo3 Pathway in Mice.
Zhao Z, Yao J, Guo Z, Song L, Ma J, Song Y, Ma Y, Zhao J
Biological trace element research 2026 Feb;204(2):769-785
Biological trace element research 2026 Feb;204(2):769-785
NMN/NAD(+)/SIRT1 axis activates NAMPT to ameliorate H(2)O(2)-triggered the impairment of progesterone synthesis in ovarian granulosa cells.
Wang Y, Li Q, Li Y, Ma Z, Xu H, Chen K, Li J, Lan D, Fu W
Journal of ovarian research 2026 Feb 28;19(1)
Journal of ovarian research 2026 Feb 28;19(1)
Arsenic exposure reduces testosterone synthesis partially by evoking Leydig cell ferroptosis in mouse testes.
Zhang XY, Luo Y, Liang NN, Li QS, Zhang ZH, Huang YC, Xu DX
Environmental pollution (Barking, Essex : 1987) 2026 Feb 1;390:127547
Environmental pollution (Barking, Essex : 1987) 2026 Feb 1;390:127547
Zhuling Yanzong formula ameliorates obesity-induced oligoasthenozoospermia via regulating HSL/StAR and HSL/TIMP-1.
Pan M, Zhao H, Xu F, Li J, Liu Z, Li L, Wang K, Wang T
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120319
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120319
Saffron extract alleviates D-gal-induced late-onset hypogonadism by activating the PI3K-Akt-Nrf2 signaling pathway.
Liu H, Guo Z, Zang Z, Jia B, Zhou Y, Zhang H, Fu Q
Journal of ethnopharmacology 2025 Jan 31;340:119273
Journal of ethnopharmacology 2025 Jan 31;340:119273
Characterization of Metabolic Patterns in Mouse Spermatogenesis and Its Clinical Implications in Humans.
Wang J, Chen M, Yao Y, Zhu M, Jiang Y, Duan J, Yuan Y, Li L, Chen M, Sha J
International journal of molecular sciences 2025 Jan 24;26(3)
International journal of molecular sciences 2025 Jan 24;26(3)
The Role of Primary Cilia in Modulating the Luteinization Process of Ovarian Granulosa Cells in Mice.
Long X, Min X, Xiao X, Wu Y, Yang Z, Wen X
International journal of molecular sciences 2025 Feb 27;26(5)
International journal of molecular sciences 2025 Feb 27;26(5)
DEHP-mediated oxidative stress leads to impaired testosterone synthesis in Leydig cells through the cAMP/PKA/SF-1/StAR pathway.
Yang L, Liu S, Song P, Liu Z, Peng Z, Kong D, Zhou J, Yan X, Ma K, Yu Y, Liu X, Dong Q
Environmental pollution (Barking, Essex : 1987) 2025 Feb 1;366:125503
Environmental pollution (Barking, Essex : 1987) 2025 Feb 1;366:125503
Gut-ovary axis and multiomic insights into PCOS in a DHEA-induced rat model.
Chen Z, Lu Q, Lin A, Tan M, Li W, Tang S, Feng J, Hou C, Zhu Y, Xu M, Liu T, Xia M
Scientific reports 2025 Dec 8;16(1):1191
Scientific reports 2025 Dec 8;16(1):1191
Bioactive Peptide C248 of PRDX4 Ameliorates the Function of Testicular Leydig Cells via Mitochondrial Protection.
Wei N, Yuan S, Gao L, Zhang B, Yan Z, Gao C, Meng Y, Cui Y
Antioxidants (Basel, Switzerland) 2025 Dec 22;15(1)
Antioxidants (Basel, Switzerland) 2025 Dec 22;15(1)
α-GalCer regulates acute stress-induced steroidogenesis by modulating lipid metabolism in female BALB/c mice.
Gao Y, Liu P, Peng L, Li M, Ni B
Psychoneuroendocrinology 2025 Aug;178:107481
Psychoneuroendocrinology 2025 Aug;178:107481
The downregulation of hormone-sensitive lipase and dysregulation of cholesterol receptors/transporter affect testicular lipid homeostasis and function in HFD-induced oligoasthenospermia mice.
Pan M, Li J, Wang Y, Liu Z, Li L, Wang T
Molecular medicine (Cambridge, Mass.) 2025 Aug 4;31(1):274
Molecular medicine (Cambridge, Mass.) 2025 Aug 4;31(1):274
Ti(3)C(2) nanosheet-induced autophagy derails ovarian functions.
Yang L, He Z, Hu L, Tang H, Geng Y, Tan Q, Zhang Y, Wen Y, Wu W, Gu H, Liu X
Journal of nanobiotechnology 2024 May 12;22(1):242
Journal of nanobiotechnology 2024 May 12;22(1):242
Exploring the mechanism of carbamazepine decreasing testosterone levels based on cAMP/PKA/CREB pathway.
Li J, Liu Z, Pan M, Li L, Tong X, Wang Y, Chen B, Wang T
3 Biotech 2024 Dec;14(12):305
3 Biotech 2024 Dec;14(12):305
Tributyltin chloride (TBTCL) induces cell injury via dysregulation of endoplasmic reticulum stress and autophagy in Leydig cells.
Chen P, Song Y, Tang L, Zhong W, Zhang J, Cao M, Chen J, Cheng G, Li H, Fan T, Kwok HF, Wang J, Yang C, Xiao W
Journal of hazardous materials 2023 Apr 15;448:130785
Journal of hazardous materials 2023 Apr 15;448:130785
Long-Term Maintenance and Meiotic Entry of Early Germ Cells in Murine Testicular Organoids Functionalized by 3D Printed Scaffolds and Air-Medium Interface Cultivation.
Richer G, Hobbs RM, Loveland KL, Goossens E, Baert Y
Frontiers in physiology 2021;12:757565
Frontiers in physiology 2021;12:757565
Cushing's syndrome caused by intra-adrenocortical adrenocorticotropic hormone in a dog.
Soler Arias EA, Castillo VA, Louiset E, Lefebvre H
Journal of veterinary internal medicine 2021 Dec 3;
Journal of veterinary internal medicine 2021 Dec 3;
Generation and characteristics of human Sertoli cell line immortalized by overexpression of human telomerase.
Wen L, Yuan Q, Sun M, Niu M, Wang H, Fu H, Zhou F, Yao C, Wang X, Li Z, He Z
Oncotarget 2017 Mar 7;8(10):16553-16570
Oncotarget 2017 Mar 7;8(10):16553-16570
A Dietary Medium-Chain Fatty Acid, Decanoic Acid, Inhibits Recruitment of Nur77 to the HSD3B2 Promoter In Vitro and Reverses Endocrine and Metabolic Abnormalities in a Rat Model of Polycystic Ovary Syndrome.
Lee BH, Indran IR, Tan HM, Li Y, Zhang Z, Li J, Yong EL
Endocrinology 2016 Jan;157(1):382-94
Endocrinology 2016 Jan;157(1):382-94
Ectopic cortisol-producing adrenocortical adenoma in the renal hilum: histopathological features and steroidogenic enzyme profile.
Tong A, Jia A, Yan S, Zhang Y, Xie Y, Liu G
International journal of clinical and experimental pathology 2014;7(7):4415-21
International journal of clinical and experimental pathology 2014;7(7):4415-21
Brain-derived neurotrophic factor expression in granulosa lutein cells.
Dominguez MA, Cho N, Zhang B, Neal MS, Foster WG
Reproductive biomedicine online 2011 Jan;22(1):17-24
Reproductive biomedicine online 2011 Jan;22(1):17-24
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human adrenal gland tissue were subjected to SDS PAGE followed by western blot with 15516-1-AP(HSD3B2 antibody) at dilution of 1:1500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 15516-1-AP(HSD3B2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HSD3B2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HSD3B2. This antibody recognizes human antigen. The HSD3B2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
