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- Antigen structure
- References [722]
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- Immunohistochemistry [1]
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- Product number
- 22734-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Collagen Type III (N-terminal) antibody
- Antibody type
- Polyclonal
- Description
- Collagen Type III (N-terminal) antibody (Cat. #22734-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Intestinal decontamination with rifaximin attenuates LSEC dysfunction and liver fibrosis in mice.
Elevated lactate production exacerbates PM2.5-induced pulmonary fibrosis by stabilizing TGF-β1.
RNF220 mediates K63-linked polyubiquitination of STAT3 and aggravates pathological cardiac hypertrophy.
Combination of Hypoxia-Preconditioned ADSCs and Deferoxamine Can Speed Up the Healing of Diabetic Wounds by Promoting Angiogenesis and Regulating Macrophage Polarization.
Promotion of DFU Wound Healing via BRG1-COL16A1 Axis in Fibroblasts.
Nanoparticles reveal permanent and reversible changes to lymph node biomechanics during inflammatory response.
IL-11 Drives Dermal Fibroblast Activation in Mechanical Stretch-Mediated Skin Expansion.
Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles.
Small-molecule LF3 alleviates angiotensin II-induced cardiac dysfunction via attenuating cardiac fibrosis.
Fibroblast growth factor-inducible 14 accelerates pulmonary fibrosis by inducing fibroblast senescence in mice.
Network medicine modeling of the m⁶A regulatory landscape identifies a KLF6-WTAP axis as a therapeutic target in pulmonary fibrosis.
Single-cell chromatin accessibility landscape of cardiac non-myocytes identifies tissue repair program during heart regeneration.
Fibroblast-derived BMP5 promotes tendon adhesion by inducing bone marrow mesenchymal stromal cells to differentiate into myofibroblasts.
Upregulation of T-type voltage-dependent Ca²⁺ channels in activated hepatic stellate cells promotes liver fibrosis in metabolic dysfunction-associated steatohepatitis.
Sexual dimorphism in keratoconus: transcriptomic and hormonal mechanisms underlying stromal remodelling.
High-Intensity Interval Training Outperforms Moderate-Intensity Exercise in Hyperlipidemic ApoE⁻/⁻ Mice: A Molecular and Histological Comparison.
Dynamically responsive hydrogel with mechanical stimulation enhances diabetic wound healing via activation of Piezo1-mediated efferocytosis.
Multi-omics and AI-guided discovery and validation of sisomicin as a COPA-targeting agent for pathological scar inhibition.
Rational design of FAP-targeted sEVs delivered by microneedles for precision treatment of hypertrophic scars via ferroptosis in hypertrophic scar fibroblasts.
Prostaglandin F2α impairs skin regeneration via FP receptor-mediated oxidative stress overriding autophagic protection in fibroblasts.
SiO(2) dust induces the transformation of lung fibroblasts to myofibroblasts by activating the S1P-RhoA-YAP signaling pathway.
Inhibiting fibroblast activation protein mitigates aging-related periodontitis by blocking nuclear factor kappa B-mediated osteoclastogenesis.
Ailanthone ameliorates CCl(4)-induced liver fibrosis by targeting PKM2-mediated macrophage M1 polarization and glycolytic reprogramming.
FOSL1 mediates collagen synthesis and myofibroblast transformation in aortic fibroblasts under Ang II-induced aortic dissection conditions.
CACNB2 overexpression suppresses atrial fibroblast activation and atrial fibrosis to mitigate atrial fibrillation.
Dynamic expression of type III collagen in the lesion core of post-ischemic brain colocalizing with angiogenesis and lipid droplets during fibrotic scar formation.
High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE(‑/‑) mice via the NAD(+)‑mediated SIRT1/MFN2 pathway.
ACLP promotes hypertrophic scar pathogenesis by enhancing myofibroblast activation and cholesterol synthesis-related gene expression.
QiShenYiQi dripping pills ameliorate post-myocardial infarction cardiac fibrosis via modulation of the cAMP/Rap1 and PI3K/Akt signaling pathways.
HNRNPC Promotes Keloid Progression by Modulating the Stability of N(6)-Methyladenosine-Modified WDR77 mRNA and Expression of TGF-β and SMAD3.
Reprogramming offspring liver health: maternal indole supplementation as a preventive strategy against MASLD.
Adolescent high fructose consumption induces cardiac dysfunction in adulthood via elevated histone acetylation.
A clinically translatable pathomics-based predictive model for preoperative prognostic assessment in patients with endometrial cancer.
Guiqi Yishen granule alleviates obstructive nephropathy-induced renal fibrosis by targeting PI3K/AKT signaling pathway.
BACH1 is stabilized by vitamin E and attenuates the formation of hypertrophic scar through the Wnt/β-catenin pathway.
Targeting Tumor Necrosis Factor-α Mitigates Glucose Fluctuation-Induced Aortic Valve Fibrosis: Insights From Diabetic Rat Models.
Hepatic stellate cells shape the ECM-disorganized and immunosuppressive microenvironment via CCL11/CCR3 axis in lenvatinib-treated hepatocellular carcinoma.
DOT1L promotes phenotypic transition of vascular smooth muscle cells following vascular injury in diabetes through activation of the FGFR4/PI3K/AKT/Jag/Notch signaling pathway.
Lipid Nanoparticles Enable Efficient EGF mRNA Delivery for Wound Healing.
Integrated metabolomics and 16S rRNA sequencing reveal the mechanism of total flavones of Abelmoschus manihot (L.) Medic against liver fibrosis.
Role of CTGF-LRP1 in impaired healing of cesarean section incisions.
Prussian blue nanoparticles targeting multiple PANoptosome-mediated PANoptosis for myocardial ischemia-reperfusion injury therapy.
Hydroxytyrosol Prevents Metabolic-Associated Steatohepatitis by Inhibiting SOCS2-Mediated Ferroptosis in High-Fat Diet Mice.
FGF2 rescues denervation-induced muscle atrophy in Ambystoma mexicanum.
Nur77 Regulates the Phosphorylation of Smad3, Thereby Influencing Skeletal Muscle Fibrosis Caused by Obesity.
Gamma delta T cells promote intestinal fibrosis via an interleukin-17A-induced transforming growth factor-beta signaling pathway in fibroblasts.
Protective Effects of Agrimonia pilosa Ledeb. In Myocardial Fibrosis: Inhibition of Mitophagy Mediated by the FOXO Signaling Pathway.
The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis.
Loss of PTH 1 receptor signaling in periodontal cells drives cementum dysfunction and molar ankylosis in mice.
18-β-glycyrrhetinic acid facilitates nuclear-mitochondrial communications to alleviate oxidative stress through HMGB1-cGAS-Mul1 axis in tendinopathy.
Neddylation of STAT3 is a potential therapeutic target for MASLD.
GPR30-mediated NETs degradation via Trex1 in heart failure of aged female mice.
Salidroside ameliorates skin aging in male mice by promoting collagen regeneration via modulation of FOS and MMP9.
Integrated transcriptome and proteome analysis identifies keratins as key regulators of corneal scarring in a murine model.
TAGLN-RhoA/ROCK2-SLC2A3-mediated Mechano-metabolic Axis Promotes Skin Fibrosis.
Inhibition of Mettl3 alleviates low-dose cisplatin-induced renal fibrosis and enhances the chemotherapeutic efficacy in mouse models of cancer.
Mechanical stretch-induced IGF2 overexpression in epidermal keratinocytes promotes hypertrophic scar formation through the IGF1R/p-c-Jun axis.
Fibroblast Activation Protein-Targeted CAR-T Cells Induce Apoptosis in Murine Cardiac Myofibroblasts.
Overexpression of Decorin Optimizes the Treatment Efficacy of Umbilical Cord Mesenchymal Stem Cells in Bleomycin-Induced Pulmonary Fibrosis in Rats.
NIR-II Imaging Guided Accurate Identification of Paraspinal Muscle Degeneration Through Targeting the Lysosomal Membrane Protein Sidt2.
A Critical Role for the Mitochondrial Pyruvate Carrier in Hepatic Stellate Cell Activation.
Pro-inflammatory cytokines disrupt in vitro preantral follicle development by targeting granulosa and theca cell functions.
Targeted ferroptosis of myofibroblasts by tubeimoside I attenuates hypertrophic scar formation.
Isorhamnetin attenuates renal interstitial fibrosis by targeting TWEAK/Fn14-mediated epithelial-mesenchymal transition.
Synergistic effects of retinol and retinyl palmitate in alleviating UVB-induced DNA damage and promoting the homologous recombination repair in keratinocytes.
Mechanical stress contributes to ligamentum flavum hypertrophy by inducing local inflammation and myofibroblast transition in the innovative surgical rabbit model.
Roles of retinoic acid-related orphan receptor α in high glucose-induced cardiac fibroblasts proliferation.
Single-cell RNA sequencing reveals that myeloid S100A8/A9 is a novel regulator of the transition from adaptive hypertrophy to heart failure after pressure overload.
The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation.
Receptor activity-modifying protein 1 regulates the differentiation of mouse skin fibroblasts by downregulating α-SMA expression via suppression of high mobility group AT-hook 1 to promote skin wound repair.
Decoding HuH-7: a comprehensive genetic and molecular portrait of a widely used hepatocellular carcinoma model.
Restoration of tendon repair microenvironment by grapefruit exosome-loaded microneedle system for tendinopathy therapy.
Saliva-derived exosomes regulate fibroblast metabolic reprogramming in skin wound healing.
The endogenous glutamatergic transmitter system promotes collagen synthesis in cardiac fibroblasts under hypoxia.
Rapid cutaneous wound healing in nude mice by fetal skin-derived stem cells involves enhanced collagen secretion and angiogenesis.
Photocrosslinkable hydrogel of kartogenin functionalized chitosan methacrylate preserves chondrogenesis.
Novel partial common bile duct ligation procedure in rats with reduced mortality and delayed onset of cirrhosis.
Parathyroid glands exhibit reduced parenchymatic chief cells and increased extracellular collagen as a response to a long-term low-phosphorus diet in pigs.
5-Aminolevulinic acid-mediated photodynamic therapy improves scar healing of laryngeal wounds in rats.
TGF-β-mediated epithelial-mesenchymal transition of keratinocytes promotes fibrosis in secondary lymphedema.
Chrysin inhibits hypertrophic scar formation through TGF-β/Smad signaling pathways.
HSF2 drives breast cancer progression by acting as a stage-specific switch between proliferation and invasion.
A two-stage transdermal drug delivery system comprising sono-phase-change transfersomes for non-invasive deep dermal delivery.
Unraveling the therapeutic mechanisms of Bufei Yiqi decoction in pulmonary fibrosis: Modulation of autophagy and glycolysis pathways.
Colla Corii Asini regulate collagen regeneration in UV exposure-induced skin photoaging in mice.
JunB orchestrates macrophage-fibroblast crosstalk in silica nanoparticle-induced pulmonary fibrosis.
Canagliflozin-driven cellular re-differentiation and migration inhibition in vascular smooth muscle cells via PTEN upregulation.
Engineered decellularized tendon hydrogel with sustained zinc ion release orchestrates anti-inflammatory microenvironment and functional regeneration in Achilles tendinopathy.
High-Yield Extruded Nanovesicles From Adipose Stem Cells Promote High-Quality Healing of Diabetic Wound Through WNT/β-Catenin Pathway Activation.
Cathepsin S Contributes to Bladder Fibrosis Following Bladder Outlet Obstruction via IL-6 Trans-signaling.
Design and Synthesis of Senescence-Targeted Prodrugs with Senomorphic and Senolytic Properties To Mitigate Chemotherapy-Induced Kidney Injury.
Mitochondrial one-carbon metabolism is required for TGF-β-induced glycine synthesis and fibrotic responses.
Reduced expression of PDZK1 mediates fibroblast activation and cardiac fibrosis via EGFR phosphorylation in diabetic cardiomyopathy.
l-cysteine rescues radiation induced ferroptosis and boosts wound healing through fibroblasts proliferation and migration.
Porous chitin nanofibers combined with adipose-derived stem cells promote diabetic wound healing via PPAR-γ activation.
BCAA exaggerated acute and chronic ischemic heart disease through promotion of NLRP3 via Sirt1.
Comprehensive analysis of extracellular matrix remodelling via cyclophilin inhibition in human models of alcohol-related liver fibrosis.
The total xanthones from Gentianella acuta alleviate acute myocardial infarction by targeting BRD4-mediated cardiomyocyte pyroptosis and inflammation.
The Composite Antiadhesion Barrier Facilitated Fibroblast Autophagy Activation for Tendon Repair.
Mechanistic effects of percutaneous needle fasciotomy combined with stretching on early-stage skeletal muscle fibrosis in rats: focus on the TGF-β1/Smad signaling pathway.
Ustekinumab enhances intestinal stenosis resolution by modulating fibrotic pathways in crohn's disease: a retrospective single-center study with translational analysis.
From Gene to Scar: Proteome-Wide Causal Insights into Keloid Pathogenesis and Prevention.
BNC2 as a novel driver of pancreatic cancer progression through transcriptional regulation of COL3A1 and epithelial-to-mesenchymal transition.
Lysyl Oxidases Are Necessary for Myometrial Contractility and On-time Parturition in Mice.
Targeting PIM1 by Bruceine D attenuates skin fibrosis via myofibroblast ferroptosis.
Collagen fiber and cellular dynamics of axolotl skin with aging.
SIRT1 Alleviates Oxidative Stress-Induced Mitochondrial Dysfunction and Mitochondria-Associated Membrane Dysregulation in Stress Urinary Incontinence.
Single-cell and spatial RNA sequencing identify divergent microenvironments and progression signatures in early- versus late-onset prostate cancer.
LA-peptide Hydrogel-Regulation of macrophage and fibroblast fates and their crosstalk via attenuating TGF-β to promote scarless wound healing.
Engrailed-1 inactivation leads to scarless skin wound healing through extracellular matrix remodeling.
From Invaginating Site to Deep Lesion: Spatial Transcriptomics Unravels Ectopic Endometrial Penetration Features in Adenomyosis.
Enhancing Tendon Regeneration: Investigating the Impact of Topography on the Secretome of Adipose-Derived Stem Cells.
CILP1 interacting with YBX1 promotes hypertrophic scar formation by suppressing PPARs transcription.
GSTP1 inhibits angiotensin II-induced atrial fibrillation by regulating ferroptosis.
Transcriptional Study of Radiofrequency Device Using Experimental Mouse Model.
Pulmonary Injury Induced via Metal-Organic Frameworks (MOFs): ROS Generation and Inflammatory Responses Mediated by HKUST-1.
Serum-free endothelial cell culture medium for vascular smooth muscle cells sheet formation.
Superoxide Anion (O(2)(-•)) Leading to Pulmonary Toxicity of Metal-Organic Frameworks (MOFs).
Mesenchymal stem cell exosomes regulate TGFβ/Smad3 by decreasing the METTL3-NEAT1 axis to inhibit scar progression after breast surgery.
Aggressive characteristics of tumor deposits in colorectal cancer highlight the need for staging refinement in patients with 0-3 metastatic lymph nodes.
Exploring the mechanism of tiRNA-Val-CAC-002 in the pathogenesis of oral submucous fibrosis.
Bone Marrow Aspirate Concentrate Combined With an Appropriate Carrier Effectively Promotes Bone-Tendon Interface Healing in a Rabbit Model of Chronic Rotator Cuff Tear.
LINC00525 promotes cell proliferation and collagen expression through feedforward regulation of TGF-β signaling in hypertrophic scar fibroblasts.
Lnc PVT1 facilitates TGF-β1-induced human cardiac fibroblast activation in vitro and ISO-induced myocardial fibrosis in vivo through regulating MYC.
Ergothioneine Ameliorates Liver Fibrosis by Inhibiting Glycerophospholipids Metabolism and TGF-β/Smads Signaling Pathway: Based on Metabonomics and Network Pharmacology.
Mitochondrial NAD(+) deficiency in vascular smooth muscle impairs collagen III turnover to trigger thoracic and abdominal aortic aneurysm.
Shenmai Injection Reduces Cardiomyocyte Apoptosis Induced by Doxorubicin through miR-30a/Bcl-2.
CD39 Contributes to the Ability of Cell Invasion in Heterogeneity of Colorectal Cancer.
Anti-fibrosis effect and its mechanism of atractylenolide III on post-traumatic extending knee joint contracture in rats.
Connexin 43 dephosphorylation mediates the Dchs1/YAP/TEAD signaling pathway to induce cardiac fibrosis.
Ubiquitin-specific peptidase 10 promotes renal interstitial fibrosis progression through deubiquitinating and stabilizing P53 protein.
Intravenous injection of PCSK9 gain-of-function mutation in C57BL/6J background mice on Angiotensin II-induced AAA.
The role of fibromodulin in myocardial fibrosis in a diabetic cardiomyopathy rat model.
Ultrasound-Triggered Oxygen Release System for Accelerating Wound Healing of Diabetic Foot Ulcers.
Targeting the E Prostanoid Receptor EP4 Mitigates Cardiac Fibrosis Induced by β-Adrenergic Activation.
Extracellular Mitochondrial-Derived Vesicles Affect the Progression of Diabetic Foot Ulcer by Regulating Oxidative Stress and Mitochondrial Dysfunction.
M2 macrophages promote PKM2 production in fibroblasts to alleviate UVB-induced photoaging.
CDC20 protects the heart from doxorubicin-induced cardiotoxicity by modulating CCDC69 degradation.
Butyrate Ameliorates Graves' Orbitopathy Through Regulating Orbital Fibroblast Phenotypes and Gut Microbiota.
Cyanidin-3-glucoside upregulated NDRG2 through the PI3K/AKT pathway to alleviate EMT and ECM in renal fibrosis.
Genetic and Molecular Characterization of H9c2 Rat Myoblast Cell Line.
Abnormal collagen deposition mediated by cartilage oligomeric matrix protein in the pathogenesis of oral submucous fibrosis.
Extracellular Matrix Reorganization During Endometrial Decidualization.
CDX1 improves nicotine induced cardiac fibroblasts activation and cardiomyocyte hypertrophy by alleviating autophagic flux impairment through modulation of LAPTM4B.
PPDPF preserves integrity of proximal tubule by modulating NMNAT activity in chronic kidney diseases.
Low intensity pulsed ultrasound alleviates synovial fibrosis in osteoarthritis via the PI3K/AKT pathway.
Discovery and Functional Characterization of a Recombinant Fragment of Human Collagen Type XVII.
Ciliary neurotrophic factor (CNTF) contributes to pelvic organ prolapse by modulating collagen expression via the JAK2-STAT3 pathway.
Trbp inhibits cardiac fibrosis through TGF-β pathway-mediated cross-talk between cardiomyocytes and fibroblasts.
Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis.
KLC3 activates PI3K/AKT signaling and promotes ovarian cancer cell proliferation and migration through COL3A1.
Multi-stage cooperative ROS-responsive hydrogel platform for drug delivery in myocardial ischemia-reperfusion injury repair.
Multifunctional chitosan-gelatin hydrogel inspired by traditional Chinese medicine for promoting malignant wound healing.
Ultrasound-responsive taurine lipid nanoparticles attenuate oxidative stress and promote macrophage polarization for diabetic wound healing.
Mai-wei-yang-fei decoction protects against pulmonary fibrosis by reducing telomere shortening and inhibiting AECII senescence via FBW7/TPP1 regulation.
Network pharmacology and experimental validation reveals the potential therapeutic effects of Polygonum cuspidatum against odontogenic keratocyst.
Aerobic Exercise Upregulates Renal-Derived ELABELA to Improve Myocardial Fibrosis by Activating APJ-AMPK-Sirt1 and Inhibiting TGFβ1-Smad2/3 Signaling Pathways in Myocardial Infarction Mice.
TIMP1 regulation of cardiac fibroblast proliferation via the TGF-β/Smad pathway in an in vitro model of atrial fibrillation.
Heshuxiaoji pill suppresses steatohepatitis and fibrosis by regulating the AngII-BACH1 mediated vasoconstriction.
Network pharmacology and bioinformatics analysis reveals: NXC improves cardiac lymphangiogenesis through miR-126-3p/SPRED1 regulating the VEGF-C axis to ameliorate post-myocardial infarction heart failure.
PRDM16 acts as a homeostasis regulation factor to suppress the transition of AKI to CKD via upregulation of eukaryotic initiation factor 6.
Nobiletin from Citrus reticulata Blanco alleviates pulmonary fibrosis through inhibiting the PI3K/AKT pathway and epithelial-mesenchymal transition.
Biochanin a Alleviated Doxorubicin-Induced Cardiotoxicity but Did not Interfere With the Antitumor Effect of Doxorubicin.
FABP4 Inhibitor Improves Right Ventricular Fibrosis in Metabolic Syndrome- Related Pulmonary Hypertension due to Left Heart Disease in Mice.
Hypoxia Induces HIF-1α Activation in Tendon Stem Cells to Enhance Extracellular Vesicle-Mediated Tendon Repair.
Identifying fibroblast-derived sFRP2 as a therapeutic target and engineering siRNA therapy for uterine scarring.
Gluconic acid alleviates hypertrophic scar formation through binding PLOD1, reducing p-AKT signaling and activating autophagy.
Enhanced THBS2 promotes collagen synthesis and inflammatory secretome of fibroblasts in idiopathic pulmonary fibrosis.
Human adipose-derived mesenchymal stem cell-derived exosomes induce epithelial remodeling and anti-scar healing revealed by single-cell RNA sequencing.
Alleviation of fibrosis and oxidative stress in pressure overload-induced cardiac remodeling and heart failure via SIRT3 activation by colchicine.
Epac1 Inhibits Orbital Fibroblast Activation to Ameliorate Thyroid-Associated Orbitopathy-Like Features Through the JAK/STAT Signaling Pathway.
Identification and localization of adhesion G protein-coupled receptor expression in the murine kidney.
IGF-1 regulates LARP6-mediated collagen metabolism in vaginal fibroblasts of POP patients via the PI3K/AKT pathway.
ACE2 Inhibits Dermal Regeneration Through Ang II in Tissue Expansion.
Baricitinib represses the myocardial fibrosis via blocking JAK/STAT and TGF-β1 pathways in vivo and in vitro.
Efficacy and mechanism of Schisandra chinensis active component Gomisin A on diabetic skin wound healing: network pharmacology and in vivo experimental validation.
Comparison of chemical composition between imitation wild and transplanted Astragali Radix and their therapeutic effects on heart failure.
UHRF1 promotes epithelial-mesenchymal transition mediating renal fibrosis by activating the TGF-β/SMAD signaling pathway.
Highly effective treatment of bacterial infection-accompanied wounds by fat extract-embedded phototherapeutic hydrogel.
Gualou Xiebai Banxia Decoction suppresses cardiomyocyte apoptosis in mice after myocardial infarction through activation of acetaldehyde dehydrogenase 2.
PTB Regulates Keloid Fibroblast Migration and Proliferation Through Autophagy.
Nicotinamide N-methyltransferase negatively regulates metastasis-promoting property of cancer-associated fibroblasts in lung adenocarcinoma.
Nicotinamide n-methyltransferase inhibitor synergizes with sodium-glucose cotransporter 2 inhibitor to protect renal tubular epithelium in experimental models of type 2 diabetes mellitus.
α-arbutin prevents UVA-induced skin photodamage via alleviating DNA damage and collagen degradation in NIH-3T3 cells.
Engineering Macrophage-Derived Exosome to Deliver Pirfenidone: A Novel Approach to Combat Silicotic Pulmonary Fibrosis.
Asiatic acid improves the damage of HaCaT cells induced by nitrogen mustard through inhibiting endoplasmic reticulum stress.
Danggui niantong decoction attenuates synovial fibrosis through regulating PI3k/AKT signaling pathway.
Keratinocyte-driven dermal collagen formation in the axolotl skin.
Growth Differentiation Factor 15 Inhibits Cardiac Fibrosis, Oxidative Stress, Inflammation, and Apoptosis in a Rat Model of Heart Failure with Preserved Ejection Fraction.
IFN-γ-mediated inhibition of JAK/STAT signaling via nano-scutellarin treatment is an efficient strategy for ameliorating liver fibrosis.
Early assessment and treatment of ventricular remodeling in vivo via a targeted ultrasonic molecular probe loaded with oxygen and cholecystokinin.
Aqueous extract of Cornus officinalis alleviate NAFLD via protecting hepatocytes proliferation through regulation of the tricarboxylic acid cycle.
Intelligent sequential degradation hydrogels by releasing bimetal-phenolic for enhanced diabetic wound healing.
Uncovering the mechanistic basis of Rheum palmatum L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular docking, and experimental validation.
Concentrated Micronized Fat Ameliorates Skin Fibrosis in Bleomycin-Induced Murine Model and Enhances Fat Graft Survival.
Astragaloside IV protects against high altitude hypoxia-induced cardiac injury through the CaSR-NF-kB and EGFR-PI3K-AKT-MDM2 pathways.
Hypericin-mediated photodynamic therapy promotes apoptosis and inhibits fibrosis by inducing HMOX1-mediated ferroptosis in hypertrophic scar fibroblasts.
Different Intensities of Exercise Affect the Prognosis of Ventricular Aneurysm in Mice by Regulating the Progression of Cardiac Fibrosis.
Shenfu injection inhibits myocardial fibrosis by regulating glycolysis through the PI3K-AKT/HIF-1α signaling pathway.
Incorporating Stem Cell-Derived Small Extracellular Vesicles into a Multifunctional OHAMA-EPL Hydrogel Spray for Rapid Healing of Infected Skin Wounds.
Loss of MFAP5 and Its Effect on Skin Homeostasis and Wound Healing.
Kirenol attenuates pressure overload-induced heart failure by enhancing autophagy in macrophages.
Loss of Trim31 Worsens Cardiac Remodeling in a Mouse Model of Heart Failure by Enhancing the Activation of the NLRP3 Inflammasome.
Dissolvable microneedle-assisted transdermal administration of diacerein nanoparticles achieved satisfactory therapeutic effects in tendon-bone insertion repair by reducing oxidative stress and inflammation.
Platelet-rich plasma-derived exosomes have the novel ability to alleviate insertional Achilles tendinopathy by promoting tenogenesis in tendon stem/progenitor cells.
Mesenchymal Stem Cell-Derived Extracellular Vesicles Embedded in a Self-Adaptive Multifunctional Hydrogel for Rapid Healing of Infected Wounds.
Butyrate protects against myocardial ischemia injury and cardiomyocyte pyroptosis by inhibiting MALT1-mediated Nrf2 ubiquitination and degradation.
SRPK1 is a significant factor in driving the progression of diabetic kidney fibrosis.
Paclitaxel-mediated microtubule stabilization regulates flexor tendon repair in rats.
Nanofat promotes wound healing in skin following exposure to ionizing radiation.
Extracellular matrix reorganization during endometrial decidualization.
MSC-derived exosomes improve endometrial fibrosis via the lncRNA IGF2R/ miR-143-5p/AQP8 axis.
[Haematococcus pluvialis alleviates bleomycin-induced pulmonary fibrosis in mice by inhibiting transformation of lung fibroblasts into myofibroblast].
Nanoparticles reveal permanent and reversible changes to lymph node biomechanics during inflammatory response.
Tanshinone IIA alleviates pulmonary fibrosis by modulating glutamine metabolic reprogramming based on [U-(13)C(5)]-glutamine metabolic flux analysis.
Mesenteric adipose-derived exosomal TINAGL1 enhances intestinal fibrosis in Crohn's Disease via SMAD4.
Nrf2 deficiency aggravates hepatic cadmium accumulation, inflammatory response and subsequent injury induced by chronic cadmium exposure in mice.
BMAL1 Regulates Collagen Production in the Myometrium and Leiomyomas.
ErTao decoction alleviates liver fibrosis by suppressing STING-mediated macrophages and NLRP3 inflammasome activation.
LIMA1 O-GlcNAcylation Promotes Hepatic Lipid Deposition through Inducing β-catenin-Regulated FASn Expression in Metabolic Dysfunction-Associated Steatotic Liver Disease.
Fermented Cordyceps Powder alleviates silica-induced inflammation and fibrosis by inhibiting M1 macrophage polarization via the HMGB1-TLR4-NF-κB pathway.
Chrysophanol Attenuates Cardiac Fibrosis and Arrhythmia by Suppressing the Endoplasmic Reticulum Stress/Pyroptosis Axis and Inflammation.
Preventive Administration of Quercetin Promotes Survival and Reduces Adverse Ventricular Remodeling after myocardial infarction through facilitating M2-like macrophage polarization.
A Novel Mechanism of the p53 Isoform Δ40p53α in Regulating Collagen III Expression in TGFβ1-Induced LX-2 Human Hepatic Stellate Cells.
CAFs activated by YAP1 upregulate cancer matrix stiffness to mediate hepatocellular carcinoma progression.
Dehydrocorydaline attenuates bleomycin-induced pulmonary fibrosis by inhibiting fibroblast activation.
The antifibrotic potential of transglutaminase 2 inhibition beyond TGFβ1 release in human kidney tissue and isolated cell cultures.
Lysozyme promotes renal fibrosis through the JAK/STAT3 signal pathway in diabetic nephropathy.
Swimming alleviates myocardial fibrosis of type II diabetic rats through activating miR-34a-mediated SIRT1/PGC-1α/FNDC5 signal pathway.
Network pharmacology and experimental verification to decode the action of Qing Fei Hua Xian Decotion against pulmonary fibrosis.
Melatonin serves as a novel treatment in bladder fibrosis through TGF-β1/Smad and EMT.
Antioxidant Carbon Dots and Ursolic Acid Co-Encapsulated Liposomes Composite Hydrogel for Alleviating Adhesion Formation and Enhancing Tendon Healing in Tendon Injury.
Liposomes Loaded with 5-Fluorouracil Can Improve the Efficacy in Pathological Scars.
Pretreatment of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes with Quercetin Enhances the Healing of Diabetic Skin Wounds by Modulating Host-Microbiota Interactions.
Qizhu Rougan Granules suppress liver fibrosis by inhibiting the expression of the P2Y14 receptor on hepatic stellate cells.
Yishen paidu pills attenuates 5/6 nephrectomy induced kidney disease via inhibiting the PI3K/AKT/mTOR signaling pathway.
RMRP accelerates ligamentum flavum hypertrophy by regulating GSDMD-mediated pyroptosis through Gli1 SUMOylation.
Abnormal mitochondrial iron metabolism damages alveolar type II epithelial cells involved in bleomycin-induced pulmonary fibrosis.
Branched-chain amino acids deficiency promotes diabetic cardiomyopathy by activating autophagy of cardiac fibroblasts.
Activating autophagy promotes skin regeneration induced by mechanical stretch during tissue expansion.
Comprehensive analysis of disulfidptosis-related genes and the immune microenvironment in heart failure.
Short-term cryoprotectant-free cryopreservation at -20°C does not affect the viability and regenerative capacity of nanofat.
Adipose-derived stem cells derived decellularized extracellular matrix enabled skin regeneration and remodeling.
A novel senolytic drug for pulmonary fibrosis: BTSA1 targets apoptosis of senescent myofibroblasts by activating BAX.
Sustained amphiregulin expression in intermediate alveolar stem cells drives progressive fibrosis.
Melatonin alleviates aging-related heart failure through melatonin receptor 1A/B knockout in mice.
CD9 promotes TβR2-TβR1 association driving the transition of human dermal fibroblasts to myofibroblast under hypoxia.
NBQX mediates ventricular fibrillation susceptibility in rat models of anxiety via the Nrf2/HO-1 pathway.
Intermedin Alleviates Diabetic Cardiomyopathy by Up-Regulating CPT-1β through Activation of the Phosphatidyl Inositol 3 Kinase/Protein Kinase B Signaling Pathway.
Krüppel-like transcription factor 14 alleviates alveolar epithelial cell senescence by inhibiting endoplasmic reticulum stress in pulmonaryfibrosis.
Roles of m(6)A modification in regulating PPER pathway in cadmium-induced pancreatic β cell death.
Insulin-transferrin-selenium promote formation of tissue-engineered vascular grafts in early stage of culture.
Attenuation of renal fibrosis in mice due to lack of bombesin receptor-activated protein homologue.
CircNSD1 promotes cardiac fibrosis through targeting the miR-429-3p/SULF1/Wnt/β-catenin signaling pathway.
Protective effect and mechanism of lycium barbarum polysaccharide against UVB-induced skin photoaging.
Neutrophil-Mediated Nanozyme Delivery System for Acute Kidney Injury Therapy.
S100A2 activation promotes interstitial fibrosis in kidneys by FoxO1-mediated epithelial-mesenchymal transition.
LMK235 ameliorates inflammation and fibrosis after myocardial infarction by inhibiting LSD1-related pathway.
Carbon monoxide attenuates cellular senescence-mediated pulmonary fibrosis via modulating p53/PAI-1 pathway.
Modification of transvaginal polypropylene mesh with co-axis electrospun nanofibrous membrane to alleviate complications following surgical implantation.
Nanofat Improves Vascularization and Tissue Integration of Dermal Substitutes without Affecting Their Biocompatibility.
Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumor growth and metastasis.
Selenium supplementation elevated SELENBP1 to inhibit fibroblast activation in pulmonary arterial hypertension.
Identification of COL3A1 as a candidate protein involved in the crosstalk between obesity and diarrhea using quantitative proteomics and machine learning.
Dapagliflozin alleviates right heart failure by promoting collagen degradation by reducing ROS levels.
Irisin suppresses PDGF-BB-induced proliferation of vascular smooth muscle cells in vitro by activating AMPK/mTOR-mediated autophagy.
NIR-II light based combinatorial management of hypertrophic scar by inducing autophagy in fibroblasts.
The LncRNA6524/miR-92a-2-5p/Dvl1/Wnt/β-catenin axis promotes renal fibrosis in the UUO mouse model.
NAT10-mediated RNA ac4C acetylation contributes to the myocardial infarction-induced cardiac fibrosis.
Cardamonin intervenes in myocardial hypertrophy progression by regulating Usp18.
Mitophagy deficiency activates stimulator of interferon genes activation and aggravates pathogenetic cardiac remodeling.
Gastrodin attenuates diabetic cardiomyopathy characterized by myocardial fibrosis by inhibiting the KLK8-PAR1 signaling axis.
The in vivo effects of knockdown of long non-coding RNA XIST on fibroid growth and gene expression.
HIF-1α knockdown attenuates phenotypic transformation and oxidative stress induced by high salt in human aortic vascular smooth muscle cells.
Astilbin improves the therapeutic effects of mesenchymal stem cells in AKI-CKD mice by regulating macrophage polarization through PTGS2-mediated pathway.
Dynamic relationship among extracellular matrix and body wall cells in Hirudo verbana morphogenesis.
Inducible Fgf13 ablation alleviates cardiac fibrosis via regulation of microtubule stability.
CXCL4:NLRP3-mediated pyroptosis product that regulates cardiac fibrosis.
Association of attenuated leptin signaling pathways with impaired cardiac function under prolonged high-altitude hypoxia.
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity.
Neferine mitigates angiotensin II-induced atrial fibrillation and fibrosis via upregulation of Nrf2/HO-1 and inhibition of TGF-β/p-Smad2/3 pathways.
Empagliflozin attenuates liver fibrosis in high-fat diet/streptozotocin-induced mice by modulating gut microbiota.
Therapeutic potential and mechanisms of Rifaximin in ameliorating iron overload-induced ferroptosis and liver fibrosis in vivo and in vitro.
Integrin β8 prevents pericyte-myofibroblast transition and renal fibrosis through inhibiting the TGF-β1/TGFBR1/Smad3 pathway in diabetic kidney disease.
Bilirubin/morin self-assembled nanoparticle-engulfed collagen/polyvinyl alcohol hydrogel accelerates chronic diabetic wound healing by modulating inflammation and ameliorating oxidative stress.
Machine learning and single-cell transcriptome profiling reveal regulation of fibroblast activation through THBS2/TGFβ1/P-Smad2/3 signalling pathway in hypertrophic scar.
Mac-1 deficiency ameliorates pressure overloaded heart failure through inhibiting macrophage polarization and activation.
Downregulation of the kidney glucagon receptor, essential for renal function and systemic homeostasis, contributes to chronic kidney disease.
DNMT1 methylation of LncRNA-ANRIL causes myocardial fibrosis pyroptosis by interfering with the NLRP3/Caspase-1 pathway.
Human amniotic MSCs-mediated anti-inflammation of CD206(hi)IL-10(hi) macrophages alleviates isoproterenol-induced ventricular remodeling in mice.
Effects of gas signaling molecule SO(2) in cardiac functions of hyperthyroid rats.
The total xanthones extracted from Gentianella acuta alleviates HFpEF by activating the IRE1α/Xbp1s pathway.
CILP2 promotes hypertrophic scar through Snail acetylation by interaction with ACLY.
Protective role of hydrogen sulfide against diabetic cardiomyopathy by inhibiting pyroptosis and myocardial fibrosis.
Activation of the Wnt/β-catenin signalling pathway enhances exosome production by hucMSCs and improves their capability to promote diabetic wound healing.
Platelet membrane biomimetic nanoparticle-targeted delivery of TGF-β1 siRNA attenuates renal inflammation and fibrosis.
In Vivo Effects of Bay 11-7082 on Fibroid Growth and Gene Expression: A Preclinical Study.
Single-cell transcriptomic-informed deconvolution of bulk data identifies immune checkpoint blockade resistance in urothelial cancer.
Targeting the long non-coding RNA MIAT for the treatment of fibroids in an animal model.
Potential Involvement of M1 Macrophage and VLA4/VCAM-1 Pathway in the Valvular Damage Due to Rheumatic Heart Disease.
C-phycocyanin reinforces autophagy to block pulmonary fibrogenesis by inhibiting lncIAPF biogenesis.
Effects of Acupotomy on Immobilization-Induced Gastrocnemius Contracture and Fibrosis in Rats via Wnt/β-Catenin Signaling.
Resistance exercise upregulates Irisin expression and suppresses myocardial fibrosis following myocardial infarction via activating AMPK-Sirt1 and inactivating TGFβ1-Smad2/3.
Microvascular Fragment-Loaded Platelet-Rich Plasma Dressing Promotes Cutaneous Wound Healing.
LDHA contributes to nicotine induced cardiac fibrosis through autophagy flux impairment.
DKK1 loss promotes endometrial fibrosis via autophagy and exosome-mediated macrophage-to-myofibroblast transition.
Zhen-wu-tang protects against myocardial fibrosis by inhibiting M1 macrophage polarization via the TLR4/NF-κB pathway.
The mechano-chemical circuit in fibroblasts and dendritic cells drives basal cell proliferation in psoriasis.
Mesenchymal stem cells ameliorate inflammation and pyroptosis in diabetic cardiomyopathy via the miRNA-223-3p/NLRP3 pathway.
CircSMAD3 represses SMAD3 phosphorylation and ameliorates cardiac remodeling by recruiting YBX1.
MBNL2 promotes aging-related cardiac fibrosis via inhibited SUMOylation of Krüppel-like factor4.
Designer cellular spheroids with DNA origami for drug screening.
Procyanidin C1 inhibits bleomycin-induced pulmonary fibrosis in mice by selective clearance of senescent myofibroblasts.
Isorhamnetin inhibits hypertrophic scar formation through TGF-β1/Smad and TGF-β1/CREB3L1 signaling pathways.
Caveolin-1 scaffolding domain-derived peptide enhances erectile function by regulating oxidative stress, mitochondrial dysfunction, and apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury.
Multi-omics analyses reveal bacteria and catalase associated with keloid disease.
Endogenous hydrogen sulphide deficiency and exogenous hydrogen sulphide supplement regulate skin fibroblasts proliferation via necroptosis.
Metabolic reprogramming driven by EZH2 inhibition depends on cell-matrix interactions.
Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling.
Biochanin A inhibits cardiac hypertrophy and fibrosis in vivo and in vitro.
Zhilong Huoxue Tongyu capsule alleviates myocardial fibrosis by improving endothelial cell dysfunction.
Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid.
Intermittent mild cold stimulation alleviates cold stress-induced pulmonary fibrosis by inhibiting the TGF-β1/Smad signaling pathway in broilers.
Metabolomics reveals that chronic restraint stress alleviates carbon tetrachloride-induced hepatic fibrosis through the INSR/PI3K/AKT/AMPK pathway.
CTRP3 alleviates mitochondrial dysfunction and oxidative stress injury in pathological cardiac hypertrophy by activating UPRmt via the SIRT1/ATF5 axis.
COL3A1 is a potential diagnostic biomarker for synovial chondromatosis and affects the cell cycle and migration of chondrocytes.
Self-assembled coating with a metal-polyphenolic network for intraocular lens modification to prevent posterior capsule opacification.
Phomopsterone B Alleviates Liver Fibrosis through mTOR-Mediated Autophagy and Apoptosis Pathway.
Tanshinone IIA ameliorates energy metabolism dysfunction of pulmonary fibrosis using (13)C metabolic flux analysis.
The Upregulation of Leucine-Rich Repeat Containing 1 Expression Activates Hepatic Stellate Cells and Promotes Liver Fibrosis by Stabilizing Phosphorylated Smad2/3.
Growth Factors-Loaded Temperature-Sensitive Hydrogel as Biomimetic Mucus Attenuated Murine Ulcerative Colitis via Repairing the Mucosal Barriers.
Buyang Huanwu Decoction suppresses cardiac inflammation and fibrosis in mice after myocardial infarction through inhibition of the TLR4 signalling pathway.
Halofuginone ameliorates the susceptibility to atrial fibrillation by activating the PI3K/Akt signaling pathway.
Geniposide alleviates heart failure with preserved ejection fraction in mice by regulating cardiac oxidative stress via MMP2/SIRT1/GSK3β pathway.
α-Mangostin Attenuates Blood Pressure and Reverses Vascular Remodeling by Balancing ACE/AT1R and ACE2/Ang-(1-7)/MasR Axes in Ang II-Infused Hypertensive Mice.
Sec13 promotes glycolysis by inhibiting Ubqln1 mediated Pgm1 ubiquitination in ALI.
Pharmacological modulation of transglutaminase 2 in the unilateral ureteral obstruction mouse model.
MicroRNA-668 alleviates renal fibrosis through PPARα/PGC-1α pathway.
Tubuloside A alleviates postmyocardial infarction cardiac fibrosis by inhibiting TGM2: Involvement of inflammation and mitochondrial pathway apoptosis.
Identification of key mitochondria-related genes and their potential crosstalk role with immune pattern in Idiopathic pulmonary fibrosis.
Mechanistic Study of Purple Sweet Potato Anthocyanins: Multifaceted Anti-Fibrotic Effects and Targeting of PDGFRβ in Liver Fibrosis.
Uni-directional release of ibuprofen from an asymmetric fibrous membrane enables effective peritendinous anti-adhesion.
Multiomics analysis of canine myocardium after circumferential pulmonary vein ablation: Effect of neuropeptide Y on long-term reinduction of atrial fibrillation.
Faecalibacterium prausnitzii-derived extracellular vesicles alleviate chronic colitis-related intestinal fibrosis by macrophage metabolic reprogramming.
Lipoamide Attenuates Hypertensive Myocardial Hypertrophy Through PI3K/Akt-Mediated Nrf2 Signaling Pathway.
Design, Synthesis, and Evaluation of the Selective and Orally Active LSD1 Inhibitor with the Potential of Treating Heart Failure.
Expression of insulin-like growth factor binding protein 5 in the vaginal wall tissues of older women with pelvic organ prolapse.
miR-450a-2-3p targets ERK(1/2) to ameliorate ISO-induced cardiac fibrosis in mice.
Blocking CTLA-4 promotes pressure overload-induced heart failure via activating Th17 cells.
Zonisamide attenuates pressure overload-induced myocardial hypertrophy in mice through proteasome inhibition.
Schwann cell derived pleiotrophin stimulates fibroblast for proliferation and excessive collagen deposition in plexiform neurofibroma.
Chloroxine inhibits pancreatic cancer progression through targeted antagonization of the PI3K/AKT/mTOR signaling pathway.
Interleukin-22 inhibits cardiac fibrosis by regulating fibroblast metabolic reprogramming in myocardial infarction.
STING deficiency alleviates ferroptosis through FPN1 stabilization in diabetic kidney disease.
CXCL4/CXCR3 axis regulates cardiac fibrosis by activating TGF-β1/Smad2/3 signaling in mouse viral myocarditis.
Intimomedial tears of the aorta heal by smooth muscle cell-mediated fibrosis without atherosclerosis.
Cell Senescence-Independent Changes of Human Skin Fibroblasts with Age.
Sphingolipid metabolism controls mammalian heart regeneration.
AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis.
LncRNA GAS5 restrains ISO-induced cardiac fibrosis by modulating mir-217 regulation of SIRT1.
Echinacoside alleviates airway remodeling and inflammation in an ovalbumin-induced neonatal mouse model of asthma by modulating the SIRT1-NF-κB pathway.
hUMSCs Restore Uterine Function by Inhibiting Endometrial Fibrosis via Regulation of the MMP-9/TIMP-1 Ratio in CDDP-Induced Injury Rats.
hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts.
Electric field promotes dermal fibroblast transdifferentiation through activation of RhoA/ROCK1 pathway.
Combining Porous Se@SiO(2) Nanocomposites and dECM Enhances the Myogenic Differentiation of Adipose-Derived Stem Cells.
Isoliensinine Attenuates Renal Fibrosis and Inhibits TGF-β1/Smad2/3 Signaling Pathway in Spontaneously Hypertensive Rats.
Thymoquinone affects the gemcitabine sensitivity of pancreatic cancer by regulating collagen via hypoxia inducible factor-1α.
Gastrodin attenuates renal injury and collagen deposition via suppression of the TGF-β1/Smad2/3 signaling pathway based on network pharmacology analysis.
Melatonin influences the biological characteristics of keloid fibroblasts through the Erk and Smad signalling pathways.
S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Plasma polymerized nanoparticles are a safe platform for direct delivery of growth factor therapy to the injured heart.
Sclareol attenuates liver fibrosis through SENP1-mediated VEGFR2 SUMOylation and inhibition of downstream STAT3 signaling.
Mining host candidate regulators of schistosomiasis-induced liver fibrosis in response to artesunate therapy through transcriptomics approach.
AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.
The response and resistance to drugs in ovarian cancer cell lines in 2D monolayers and 3D spheroids.
Gentianella acuta-derived Gen-miR-1 suppresses myocardial fibrosis by targeting HAX1/HMG20A/Smads axis to attenuate inflammation in cardiac fibroblasts.
TRIM44 aggravates cardiac fibrosis after myocardial infarction via TAK1 stabilization.
Riboflavin ameliorates pathological cardiac hypertrophy and fibrosis through the activation of short-chain acyl-CoA dehydrogenase.
Omentin-1 induces mechanically activated fibroblasts lipogenic differentiation through pkm2/yap/pparγ pathway to promote lung fibrosis resolution.
Calcineurin/NFATc3 pathway mediates myocardial fibrosis in diabetes by impairing enhancer of zeste homolog 2 of cardiac fibroblasts.
Core fucosylation regulates alveolar epithelial cells senescence through activating of transforming growth factor-β pathway in pulmonary fibrosis.
Qingda granule ameliorates vascular remodeling and phenotypic transformation of adventitial fibroblasts via suppressing the TGF-β1/Smad2/3 pathway.
Human adipose ECM alleviates radiation-induced skin fibrosis via endothelial cell-mediated M2 macrophage polarization.
Overexpression of KLF4 Suppresses Pulmonary Fibrosis through the HIF-1α/Endoplasmic Reticulum Stress Signaling Pathway.
Buried penis: a histological and histochemical study of dartos fascia.
Increased Expression of Adipokines in Patients With Frozen Shoulder.
Molecular insights of a CBP/β-catenin-signaling inhibitor on nonalcoholic steatohepatitis-induced liver fibrosis and disorder.
NKRF in Cardiac Fibroblasts Protects against Cardiac Remodeling Post-Myocardial Infarction via Human Antigen R.
Caveolin-1 scaffolding domain peptide prevents corpus cavernosum fibrosis and erectile dysfunction in bilateral cavernous nerve injury-induced rats.
Glucose fluctuations aggravate myocardial fibrosis via activating the CaMKII/Stat3 signaling in type 2 diabtetes.
Substrate-dependent interaction of SPOP and RACK1 aggravates cardiac fibrosis following myocardial infarction.
Blockade of IL-11 Trans-Signaling or JAK2/STAT3 Signaling Ameliorates the Profibrotic Effect of IL-11.
Macrophage RAGE deficiency prevents myocardial fibrosis by repressing autophagy-mediated macrophage alternative activation.
COL3A1, COL5A1 and COL6A2 serve as potential molecular biomarkers for osteoarthritis based on weighted gene co‑expression network analysis bioinformatics analysis.
Hepatic macrophages play critical roles in the establishment and growth of hydatid cysts in the liver during Echinococcus granulosus sensu stricto infection.
Biomimetic nanoparticles loaded lutein functionalized by macrophage membrane for targeted amelioration pressure overload-induced cardiac fibrosis.
Alpha lipoamide inhibits diabetic kidney fibrosis via improving mitochondrial function and regulating RXRα expression and activation.
Bioinformatics analysis and identification of dysregulated POSTN in the pathogenesis of keloid.
Schistosome egg antigen stimulates the secretion of miR-33-carrying extracellular vesicles from macrophages to promote hepatic stellate cell activation and liver fibrosis in schistosomiasis.
Pilose antler extract restores type I and III collagen to accelerate wound healing.
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
The p53/miR-29a-3p axis mediates the antifibrotic effect of leonurine on angiotensin II-stimulated rat cardiac fibroblasts.
Angiotensin II Type 1A Receptor Expressed in Smooth Muscle Cells is Required for Hypertensive Vascular Remodeling in Mice Infused With Angiotensin II.
Ginsenoside Re inhibits myocardial fibrosis by regulating miR-489/myd88/NF-κB pathway.
MetBil as a novel molecular regulator in ischemia-induced cardiac fibrosis via METTL3-mediated m6A modification.
miR-124-3p improves mitochondrial function of renal tubular epithelial cells in db/db mice.
Smooth muscle angiotensin II type 1A receptor is required for abdominal aortic aneurysm formation induced by angiotensin II plus β-aminopropionitrile.
Fibroblast-Derived Extracellular Vesicle-Packaged Long Noncoding RNA Upregulated in Diabetic Skin Enhances Keratinocyte MMP-9 Expression and Delays Diabetic Wound Healing.
Luteolin reduces cardiac damage caused by hyperlipidemia in Sprague-Dawley rats.
Evaluation of the effect of 3D-bioprinted gingival fibroblast-encapsulated ADM scaffolds on keratinized gingival augmentation.
TGF-β-induced PI3K/AKT/mTOR pathway controls myofibroblast differentiation and secretory phenotype of valvular interstitial cells through the modulation of cellular senescence in a naturally occurring in vitro canine model of myxomatous mitral valve disease.
Liensinine prevents ischemic injury following myocardial infarction via inhibition of Wnt/β‑catenin signaling activation.
3D-printed hydrogel particles containing PRP laden with TDSCs promote tendon repair in a rat model of tendinopathy.
Therapeutic Effects of Long-Term Administration of Tranilast in an Animal Model for the Treatment of Fibroids.
Ovariectomy with simulated vaginal delivery to establish a rat model for pelvic organ prolapse.
Decorin: a potential therapeutic candidate for ligamentum flavum hypertrophy by antagonizing TGF-β1.
hUMSCs Transplantation Regulates AMPK/NR4A1 Signaling Axis to Inhibit Ovarian Fibrosis in POI Rats.
Sacha inchi albumin delays skin-aging by alleviating inflammation, oxidative stress and regulating gut microbiota in d-galactose induced-aging mice.
In situ gel-forming oil as rectally delivering platform of hydrophobic therapeutics for ulcerative colitis therapy.
Different exercise training intensities prevent type 2 diabetes mellitus-induced myocardial injury in male mice.
Recombinant protein EBI3 attenuates Clonorchis sinensis-induced liver fibrosis by inhibiting hepatic stellate cell activation in mice.
Triptolide with hepatotoxicity and nephrotoxicity used in local delivery treatment of myocardial infarction by thermosensitive hydrogel.
Resveratrol plays an anti-fibrotic and anti-autophagy role by stimulating miR-192-5p expression in urethral fibrosis.
Qing Fei Hua Xian Decoction ameliorates bleomycin-induced pulmonary fibrosis by suppressing oxidative stress through balancing ACE-AngII-AT1R/ACE2-Ang-(1-7)-Mas axis.
The combination of exercise and metformin inhibits TGF-β1/Smad pathway to attenuate myocardial fibrosis in db/db mice by reducing NF-κB-mediated inflammatory response.
Cryptotanshinone modulates proliferation, apoptosis, and fibrosis through inhibiting AR and EGFR/STAT3 axis to ameliorate benign prostatic hyperplasia progression.
Epigenetic control of LncRNA NEAT1 enables cardiac fibroblast pyroptosis and cardiac fibrosis.
Berberin sustained-release nanoparticles were enriched in infarcted rat myocardium and resolved inflammation.
Irisin ameliorates D-galactose-induced skeletal muscle fibrosis via the PI3K/Akt pathway.
Comparative analysis of dermal collagen and lipids in cereblon ablated mice using a multimodal nonlinear optical system.
Polyphenol-driven facile assembly of a nanosized acid fibroblast growth factor-containing coacervate accelerates the healing of diabetic wounds.
SUMO1 regulates post-infarct cardiac repair based on cellular heterogeneity.
The UDPase ENTPD5 regulates ER stress-associated renal injury by mediating protein N-glycosylation.
Old age promotes retinal fibrosis in choroidal neovascularization through circulating fibrocytes and profibrotic macrophages.
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction.
Stomatin-like protein 2 deficiency exacerbates adverse cardiac remodeling.
Estrogen inhibits the differentiation of fibroblasts induced by high stiffness matrix by enhancing DNMT1 expression.
Single-cell analysis reveals lysyl oxidase (Lox)(+) fibroblast subset involved in cardiac fibrosis of diabetic mice.
Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics.
Multi-omics analysis reveals the mechanism of action of ophiopogonin D against pulmonary fibrosis.
Liensinine improves AngII-induced vascular remodeling via MAPK/TGF-β1/Smad2/3 signaling.
TrxR/Trx inhibitor butaselen ameliorates pulmonary fibrosis by suppressing NF-κB/TGF-β1/Smads signaling.
Exploring the Role of Lycium barbarum Polysaccharide in Corneal Injury Repair and Investigating the Relevant Mechanisms through In Vivo and In Vitro Experiments.
Profibrotic role of transcription factor SP1 in cross-talk between fibroblasts and M2 macrophages.
Effect of a New Hyaluronic Acid Hydrogel Dermal Filler Cross-Linked With Lysine Amino Acid for Skin Augmentation and Rejuvenation.
Oncogenic KRAS Drives Lipofibrogenesis to Promote Angiogenesis and Colon Cancer Progression.
Infused juice concentrate of Japanese plum Prunus mume attenuates inflammatory vascular remodeling in a mouse model of hypertension induced by angiotensin II.
sST2: A Bridge Between Sirt1/p53/p21 Signal-Induced Senescence and TGF-β1/Smad2/3 Regulation of Cardiac Fibrosis in Mouse Viral Myocarditis.
Matrix stiffness-induced α-tubulin acetylation is required for skin fibrosis formation through activation of Yes-associated protein.
The adipose-derived stem cell peptide ADSCP2 alleviates hypertrophic scar fibrosis via binding with pyruvate carboxylase and remodeling the metabolic landscape.
TRPA1 deficiency attenuates cardiac fibrosis via regulating GRK5/NFAT signaling in diabetic rats.
M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation.
Eicosapentaenoic Acid Preserves Mitochondrial Quality and Attenuates Cardiac Remodeling After Myocardial Infarction in Rats.
Celastrol relieves myocardial infarction-induced cardiac fibrosis by inhibiting NLRP3 inflammasomes in rats.
Tough Gelatin Hydrogel for Tissue Engineering.
NPRC deletion attenuates cardiac fibrosis in diabetic mice by activating PKA/PKG and inhibiting TGF-β1/Smad pathways.
Activating α7nAChR helps post-myocardial infarction healing by regulating macrophage polarization via the STAT3 signaling pathway.
TSG-6 inhibits hypertrophic scar fibroblast proliferation by regulating IRE1α/TRAF2/NF-κB signalling.
Peptide deregulated in hypertrophic scar-1 alleviates hypertrophic scar fibrosis by targeting focal adhesion kinase and pyruvate kinase M2 and remodeling the metabolic landscape.
Two-Pore-Domain Potassium Channel TREK-1 Mediates Pulmonary Fibrosis through Macrophage M2 Polarization and by Direct Promotion of Fibroblast Differentiation.
Suppression of SMOC2 alleviates myocardial fibrosis via the ILK/p38 pathway.
Research on the Mechanism and Prevention of Hypertension Caused by Apatinib Through the RhoA/ROCK Signaling Pathway in a Mouse Model of Gastric Cancer.
MCC950, a Selective NLRP3 Inhibitor, Attenuates Adverse Cardiac Remodeling Following Heart Failure Through Improving the Cardiometabolic Dysfunction in Obese Mice.
Senescent renal tubular epithelial cells activate fibroblasts by secreting Shh to promote the progression of diabetic kidney disease.
Loureirin A Exerts Antikeloid Activity by Antagonizing the TGF-β1/Smad Signalling Pathway.
The Traditional Chinese Medicine Formula FTZ Protects against Cardiac Fibrosis by Suppressing the TGFβ1-Smad2/3 Pathway.
Mechanism of Action of Zhi Gan Cao Decoction for Atrial Fibrillation and Myocardial Fibrosis in a Mouse Model of Atrial Fibrillation: A Network Pharmacology-Based Study.
MicroRNA-325-3p Targets Human Epididymis Protein 4 to Relieve Right Ventricular Fibrosis in Rats with Pulmonary Arterial Hypertension.
Eugenol-Preconditioned Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Antioxidant Capacity of Tendon Stem Cells In Vitro and In Vivo.
Fufang Xueshuantong Improves Diabetic Cardiomyopathy by Regulating the Wnt/β-Catenin Pathway.
p16(INK4a) Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin.
Silencing of TLR4 Inhibits Atrial Fibrosis and Susceptibility to Atrial Fibrillation via Downregulation of NLRP3-TGF-β in Spontaneously Hypertensive Rats.
Tissue Kallikrein Protects Rat Prostate against the Inflammatory Damage in a Chronic Autoimmune Prostatitis Model via Restoring Endothelial Function in a Bradykinin Receptor B2-Dependent Way.
The conditioned medium from mesenchymal stromal cells pretreated with proinflammatory cytokines promote fibroblasts migration and activation.
Keloid Patient Plasma-Derived Exosomal hsa_circ_0020792 Promotes Normal Skin Fibroblasts Proliferation, Migration, and Fibrogenesis via Modulating miR-193a-5p and Activating TGF-β1/Smad2/3 Signaling.
Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics.
STAMP2 Attenuates Cardiac Dysfunction and Insulin Resistance in Diabetic Cardiomyopathy via NMRAL1-Mediated NF-κB Inhibition in Type 2 Diabetic Rats.
Phosphatidylethanolamine-binding protein 4 deficiency exacerbates carbon tetrachloride-induced liver fibrosis by regulating the NF-κB signaling pathway.
NOX1 promotes myocardial fibrosis and cardiac dysfunction via activating the TLR2/NF-κB pathway in diabetic cardiomyopathy.
Metformin Improves the Senescence of Renal Tubular Epithelial Cells in a High-Glucose State Through E2F1.
QiShenYiQi Pill Ameliorates Cardiac Fibrosis After Pressure Overload-Induced Cardiac Hypertrophy by Regulating FHL2 and the Macrophage RP S19/TGF-β1 Signaling Pathway.
BMP-7 Upregulates Id2 Through the MAPK Signaling Pathway to Improve Diabetic Tubulointerstitial Fibrosis and the Intervention of Oxymatrine.
Extracellular Matrix-Oriented Proteomic Analysis of Periodontal Ligament Under Mechanical Stress.
A Novel miRNA From Egg-Derived Exosomes of Schistosoma japonicum Promotes Liver Fibrosis in Murine Schistosomiasis.
Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics.
Farrerol prevents Angiotensin II-induced cardiac remodeling in vivo and in vitro.
Administration of USP7 inhibitor P22077 inhibited cardiac hypertrophy and remodeling in Ang II-induced hypertensive mice.
Lycorine Inhibits Hypertrophic Scar Formation by Inducing ROS-Mediated Apoptosis.
Transcriptomic analysis supports collective endometrial cell migration in the pathogenesis of adenomyosis.
Substitution of SERCA2 Cys(674) aggravates cardiac fibrosis by promoting the transformation of cardiac fibroblasts to cardiac myofibroblasts.
LARP6 Regulates Keloid Fibroblast Proliferation, Invasion, and Ability to Synthesize Collagen.
Generation of cost-effective MXene@polydopamine-decorated chitosan nanofibrous wound dressing for promoting wound healing.
Tubular IKKβ Deletion Alleviates Acute Ischemic Kidney Injury and Facilitates Tissue Regeneration.
Atrial myocyte-derived exosomal microRNA contributes to atrial fibrosis in atrial fibrillation.
Intact Fibroblast Growth Factor 23 Regulates Chronic Kidney Disease-Induced Myocardial Fibrosis by Activating the Sonic Hedgehog Signaling Pathway.
Collagen and elastic fiber remodeling in the pregnant mouse myometrium†.
The Apelin-APJ axis alleviates LPS-induced pulmonary fibrosis and endothelial mesenchymal transformation in mice by promoting Angiotensin-Converting Enzyme 2.
Dihydroartemisinin suppresses renal fibrosis in mice by inhibiting DNA-methyltransferase 1 and increasing Klotho.
In situ hydrogel capturing nitric oxide microbubbles accelerates the healing of diabetic foot.
Epididymal white adipose tissue promotes angiotensin II-induced cardiac fibrosis in an exosome-dependent manner.
Endophilin A2 protects against renal fibrosis by targeting TGF-β/Smad signaling.
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Cell contractility and focal adhesion kinase control circumferential arterial stiffness.
Gaseous signal molecule SO(2) regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.
Loss of RTN3 phenocopies chronic kidney disease and results in activation of the IGF2-JAK2 pathway in proximal tubular epithelial cells.
Metabotropic glutamate receptor 5 blockade attenuates pathological cardiac remodelling in pulmonary arterial hypertension.
Effects of thymoquinone against angiotensin II‑induced cardiac damage in apolipoprotein E‑deficient mice.
Radix ranunculus temate saponins sensitizes ovarian cancer to Taxol via upregulation of miR-let-7b.
Near-infrared Nrf2 activator IR-61 dye alleviates radiation-induced lung injury.
EP3 enhances adhesion and cytotoxicity of NK cells toward hepatic stellate cells in a murine liver fibrosis model.
Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis.
Upregulation of Periostin Through CREB Participates in Myocardial Infarction-induced Myocardial Fibrosis.
Optimization of the saffron compound essence formula and its effect on preventing skin photoaging.
MicroRNA-24-3p alleviates cardiac fibrosis by suppressing cardiac fibroblasts mitophagy via downregulating PHB2.
Injectable recombinant human collagen-derived material with high cell adhesion activity limits adverse remodelling and improves pelvic floor function in pelvic floor dysfunction rats.
Daidzein suppresses TGF-β1-induced cardiac fibroblast activation via the TGF-β1/SMAD2/3 signaling pathway.
Transition of autophagy and apoptosis in fibroblasts depends on dominant expression of HIF-1α or p53.
Effect of ALDH1A1 Gene Knockout on Drug Resistance in Paclitaxel and Topotecan Resistant Human Ovarian Cancer Cell Lines in 2D and 3D Model.
Endoplasmic reticulum-to-Golgi trafficking of procollagen III via conventional vesicular and tubular carriers.
Protection of CAPE-pNO(2) Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Overexpression of G Protein-Coupled Receptor 40 Protects Obesity-Induced Cardiomyopathy Through the SIRT1/LKB1/AMPK Pathway.
A myogenic niche with a proper mechanical stress environment improves abdominal wall muscle repair by modulating immunity and preventing fibrosis.
Suppression of the Inhibitory Effect of circ_0036176-Translated Myo9a-208 on Cardiac Fibroblast Proliferation by miR-218-5p.
TGF-β1 mediates pathologic changes of secondary lymphedema by promoting fibrosis and inflammation.
Guanxin V alleviates acute myocardial infarction by restraining oxidative stress damage, apoptosis, and fibrosis through the TGF-β1 signalling pathway.
The Role of Verteporfin in Prevention of Periprosthetic Capsular Fibrosis: An Experimental Study.
Estrogen deficiency aggravates fluorine ion-induced renal fibrosis via the TGF-β1/Smad signaling pathway in rats.
KGF-2 Regulates STAP-2-Mediated Signal Transducer and Activator of Transcription 3 Signaling and Reduces Skin Scar Formation.
COX-2/sEH Dual Inhibitor Alleviates Hepatocyte Senescence in NAFLD Mice by Restoring Autophagy through Sirt1/PI3K/AKT/mTOR.
Revealing the mechanism of Jiegeng decoction attenuates bleomycin-induced pulmonary fibrosis via PI3K/Akt signaling pathway based on lipidomics and transcriptomics.
Overexpressed COL3A1 has prognostic value in human esophageal squamous cell carcinoma and promotes the aggressiveness of esophageal squamous cell carcinoma by activating the NF-κB pathway.
Guanxin V protects against ventricular remodeling after acute myocardial infarction through the interaction of TGF-β1 and Vimentin.
Close Association between Altered Urine-Urothelium Barrier and Tertiary Lymphoid Structure Formation in the Renal Pelvis during Nephritis.
Morphological changes of macrophages and their potential contribution to tendon healing.
Long-term explant culture: an improved method for consistently harvesting homogeneous populations of keloid fibroblasts.
Endothelial cell metabolic memory causes cardiovascular dysfunction in diabetes.
ZC3H4 promotes pulmonary fibrosis via an ER stress-related positive feedback loop.
The effect of Q-switched 1064-nm dymium-doped yttrium aluminum garnet laser on the skin barrier and collagen synthesis through miR-24-3p.
Mitigation of portal fibrosis and cholestatic liver disease in ANKS6-deficient livers by macrophage depletion.
Fully Reduced HMGB1-Containing Peptide-Based Polyurethane Scaffold with Minimal Functional Unit of Skin (MFUS) Enhances Large and Deep Wounded Skin Healing.
Uncaria Rhynchophylla attenuates angiotensin Ⅱ-induced myocardial fibrosis via suppression of the RhoA/ROCK1 pathway.
QiShenYiQi pill for myocardial collagen metabolism and apoptosis in rats of autoimmune cardiomyopathy.
Acacetin alleviates myocardial ischaemia/reperfusion injury by inhibiting oxidative stress and apoptosis via the Nrf-2/HO-1 pathway.
Targeting the Akt/PI3K/mTOR signaling pathway for complete eradication of keloid disease by sunitinib.
Activation of primary hepatic stellate cells and liver fibrosis induced by targeting TGF-β1/Smad signaling in schistosomiasis in mice.
Pinocembrin alleviates the susceptibility to atrial fibrillation in isoproterenol-induced rats.
Metformin Improves Burn Wound Healing by Modulating Microenvironmental Fibroblasts and Macrophages.
Spatio-Temporal Changes of Extracellular Matrix (ECM) Stiffness in the Development of the Leech Hirudo verbana.
C/EBP-β contributes to pig endometrial LE receptivity by targeting cell remodeling genes during implantation.
AGEs-RAGE axis mediates myocardial fibrosis via activation of cardiac fibroblasts induced by autophagy in heart failure.
Lidocaine Inhibited Tendon Cell Proliferation and Extracellular Matrix Production by Down Regulation of Cyclin A, CDK2, Type I and Type III Collagen Expression.
The compound losartan cream inhibits scar formation via TGF-β/Smad pathway.
The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.
Immunohistochemical expression of osteopontin and collagens in choroid plexus of human brains.
Botox-A improve the thyroid-associated ophthalmopathy (TAO) orbital fibroblast activation through inhibiting the TGF-β/Smad signaling.
Suppression of LMCD1 ameliorates renal fibrosis by blocking the activation of ERK pathway.
Exosomes from human adipose-derived mesenchymal stem cells inhibit production of extracellular matrix in keloid fibroblasts via downregulating transforming growth factor-β2 and Notch-1 expression.
Isoandrographolide inhibits NLRP3 inflammasome activation and attenuates silicosis in mice.
A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon.
Canine Mesenchymal Stromal Cell-Mediated Bone Regeneration is Enhanced in the Presence of Sub-Therapeutic Concentrations of BMP-2 in a Murine Calvarial Defect Model.
Mesenchymal Stem Cells With Cancer-Associated Fibroblast-Like Phenotype Stimulate SDF-1/CXCR4 Axis to Enhance the Growth and Invasion of B-Cell Acute Lymphoblastic Leukemia Cells Through Cell-to-Cell Communication.
Epicardium-Derived Tbx18(+) CDCs Transplantation Improve Heart Function in Infarcted Mice.
Therapeutic Effects of an Inhibitor of Thioredoxin Reductase on Liver Fibrosis by Inhibiting the Transforming Growth Factor-β1/Smads Pathway.
Estrogen Protects Vasomotor Functions in Rats During Catecholamine Stress.
Early Passive Leg Movement Prevents Against the Development of Heart Failure With Preserved Ejection Fraction in Rats.
PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell.
Exosomes Containing LINC00636 Inhibit MAPK1 through the miR-450a-2-3p Overexpression in Human Pericardial Fluid and Improve Cardiac Fibrosis in Patients with Atrial Fibrillation.
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
FTZ Ameliorates Diabetic Cardiomyopathy by Inhibiting Inflammation and Cardiac Fibrosis in the Streptozotocin-Induced Model.
CircRNA FAT1 Regulates Osteoblastic Differentiation of Periodontal Ligament Stem Cells via miR-4781-3p/SMAD5 Pathway.
The Preventive Effect of Decorin on Epidural Fibrosis and Epidural Adhesions After Laminectomy.
Ginsenoside Rb1 Ameliorates Diabetic Arterial Stiffening via AMPK Pathway.
Follistatin Attenuates Myocardial Fibrosis in Diabetic Cardiomyopathy via the TGF-β-Smad3 Pathway.
LncRNA Nuclear-Enriched Abundant Transcript 1 Regulates Atrial Fibrosis via the miR-320/NPAS2 Axis in Atrial Fibrillation.
Conditioned medium from adipose-derived stem cells attenuates ischemia/reperfusion-induced cardiac injury through the microRNA-221/222/PUMA/ETS-1 pathway.
Elevated IgE promotes cardiac fibrosis by suppressing miR-486a-5p.
Identifying miRNA modules associated with progression of keloids through weighted gene co-expression network analysis and experimental validation in vitro.
IGF-1-Expressing Placenta-Derived Mesenchymal Stem Cells Promote Scalding Wound Healing.
Hydrogen gas inhalation ameliorates cardiac remodelling and fibrosis by regulating NLRP3 inflammasome in myocardial infarction rats.
Effect of different exercise training intensities on age-related cardiac damage in male mice.
Changes in aortic collagen in β-aminopropionitrile-induced acute aortic dissection.
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Ghrelin ameliorates cardiac fibrosis after myocardial infarction by regulating the Nrf2/NADPH/ROS pathway.
Tryptophan catabolism is dysregulated in leiomyomas.
Mesenchymal Stem Cell-Derived Exosomes Ameliorate Dermal Fibrosis in a Murine Model of Bleomycin-Induced Scleroderma.
Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway.
Blood glucose control contributes to protein stability of Ski-related novel protein N in a rat model of diabetes.
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Exosomal MicroRNA-21 Promotes Keloid Fibroblast Proliferation and Collagen Production by Inhibiting Smad7.
Exercise Training Alleviates Cardiac Fibrosis through Increasing Fibroblast Growth Factor 21 and Regulating TGF-β1-Smad2/3-MMP2/9 Signaling in Mice with Myocardial Infarction.
Connective tissue growth factor promotes retinal pigment epithelium mesenchymal transition via the PI3K/AKT signaling pathway.
Qingda granule attenuates cardiac fibrosis via suppression of the TGF-β1/Smad2/3 signaling pathway in vitro and in vivo.
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
Controlled release of KGF-2 for regulation of wound healing by KGF-2 complexed with "lotus seedpod surface-like" porous microspheres.
Celecoxib ameliorates liver cirrhosis via reducing inflammation and oxidative stress along spleen-liver axis in rats.
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.
Umbilical cord-derived mesenchymal stem cells exert anti-fibrotic action on hypertrophic scar-derived fibroblasts in co-culture by inhibiting the activation of the TGF β1/Smad3 pathway.
SAIL: a new conserved anti-fibrotic lncRNA in the heart.
Deletion of fibroblast activation protein provides atheroprotection.
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Troxerutin Improves Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice.
Regulation of connective tissue growth factor expression by miR-133b for the treatment of renal interstitial fibrosis in aged mice with unilateral ureteral obstruction.
Microsphere-Embedded Hydrogel Sustained-Release System to Inhibit Postoperative Epidural Fibrosis.
Vincristine attenuates cardiac fibrosis through the inhibition of NLRP3 inflammasome activation.
The magnitude of airway remodeling is not altered by distinct allergic inflammatory responses in BALB/c versus C57BL/6 mice but matrix composition differs.
Periplocymarin protects against myocardial fibrosis induced by β-adrenergic activation in mice.
Huoxin Pill inhibits isoproterenol-induced transdifferentiation and collagen synthesis in cardiac fibroblasts through the TGF-β/Smads pathway.
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway.
Functional role of the long noncoding RNA X-inactive specific transcript in leiomyoma pathogenesis.
A lncRNA Gpr137b-ps/miR-200a-3p/CXCL14 axis modulates hepatic stellate cell (HSC) activation.
Pathological Alternations of Mediastinal Fat-Associated Lymphoid Cluster and Lung in a Streptozotocin-Induced Diabetic Mouse Model.
Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice.
Tenogenic adipose-derived stem cell sheets with nanoyarn scaffolds for tendon regeneration.
Cancer-Associated Fibroblast Subgroups Showing Differential Promoting Effect on HNSCC Progression.
The role of CDX2 in renal tubular lesions during diabetic kidney disease.
Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats.
Leonurine Attenuates Myocardial Fibrosis Through Upregulation of miR-29a-3p in Mice Post-myocardial Infarction.
Ginsenoside Rb1 attenuates age-associated vascular impairment by modulating the Gas6 pathway.
Epigallocatechin gallate (EGCG) attenuates myocardial hypertrophy and fibrosis induced by transverse aortic constriction via inhibiting the Akt/mTOR pathway.
Huoxue Qianyang Qutan recipe attenuates cardiac fibrosis by inhibiting the NLRP3 inflammasome signalling pathway in obese hypertensive rats.
Huoxin pill prevents acute myocardial ischaemia injury via inhibition of Wnt/β-catenin signaling.
Radiation‑induced dysfunction of energy metabolism in the heart results in the fibrosis of cardiac tissues.
Dickkopf 3: a Novel Target Gene of miR-25-3p in Promoting Fibrosis-Related Gene Expression in Myocardial Fibrosis.
M2 Macrophage-derived exosomal miR-501 contributes to pubococcygeal muscle regeneration.
Diverging targets mediate the pathological roleof miR-199a-5p and miR-199a-3p by promoting cardiac hypertrophy and fibrosis.
Effects of L-leucine on the properties of spray-dried swellable microparticles with wrinkled surfaces for inhalation therapy of pulmonary fibrosis.
Gsα deficiency facilitates cardiac remodeling via CREB/ Bmp10-mediated signaling.
Citrus alkaline extracts prevent endoplasmic reticulum stress in type II alveolar epithelial cells to ameliorate pulmonary fibrosis via the ATF3/PINK1 pathway.
ER-anchored CRTH2 antagonizes collagen biosynthesis and organ fibrosis via binding LARP6.
Zi Qi Decoction Alleviates Liver Fibrosis by Inhibiting the Toll-Like Receptor 4 (TLR4)-Related Nuclear Factor kappa b (NF-κB) and Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways.
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
Ginsenoside Rb1 Ameliorates Age-Related Myocardial Dysfunction by Regulating the NF-κB Signaling Pathway.
Exposure to Air Pollution Exacerbates Inflammation in Rats with Preexisting COPD.
MicroRNA-21-3p Engineered Umbilical Cord Stem Cell-Derived Exosomes Inhibit Tendon Adhesion.
Dexmedetomidine Exerted Anti-arrhythmic Effects in Rat With Ischemic Cardiomyopathy via Upregulation of Connexin 43 and Reduction of Fibrosis and Inflammation.
Splenectomy enhances the Ly6C(low) phenotype in hepatic macrophages by activating the ERK1/2 pathway during liver fibrosis.
hUMSCs regulate the differentiation of ovarian stromal cells via TGF-β(1)/Smad3 signaling pathway to inhibit ovarian fibrosis to repair ovarian function in POI rats.
Mechanism underlying increased cardiac extracellular matrix deposition in perinatal nicotine-exposed offspring.
Polyunsaturated fatty acid supplement alleviates depression-incident cognitive dysfunction by protecting the cerebrovascular and glymphatic systems.
Polystyrene microplastics cause cardiac fibrosis by activating Wnt/β-catenin signaling pathway and promoting cardiomyocyte apoptosis in rats.
MSC-derived exosomes protect against oxidative stress-induced skin injury via adaptive regulation of the NRF2 defense system.
Endothelin receptors promote schistosomiasis-induced hepatic fibrosis via splenic B cells.
Citri Reticulatae Pericarpium protects against isoproterenol-induced chronic heart failure via activation of PPARγ.
Construction and performance evaluation of Hep/silk-PLCL composite nanofiber small-caliber artificial blood vessel graft.
The role of Hrd1 in ultraviolet (UV) radiation induced photoaging.
KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats.
G protein-coupled receptor kinase-2: A potential biomarker for early diabetic cardiomyopathy.
Kidney targeted delivery of asiatic acid using a FITC labeled renal tubular-targeting peptide modified PLGA-PEG system.
Role of Interleukin-17 in Pathogenesis of Intestinal Fibrosis in Mice.
Administration of a mixture of triterpenoids from yeyachun and phenolic acids from danshen ameliorates carbon tetrachloride-induced liver fibrosis in mice by the regulation of intestinal flora.
Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression.
Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload.
Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling.
Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.
Psoralen attenuates bleomycin-induced pulmonary fibrosis in mice through inhibiting myofibroblast activation and collagen deposition.
Tanshinone IIA attenuates silica-induced pulmonary fibrosis via inhibition of TGF-β1-Smad signaling pathway.
Left Atrial Appendage Fibrosis and 3-Year Clinical Outcomes in Atrial Fibrillation After Endoscopic Ablation: A Histologic Analysis.
Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.
MicroRNA-29a attenuates angiotensin-II induced-left ventricular remodeling by inhibiting collagen, TGF-β and SMAD2/3 expression.
β2-microglobulin as a biomarker of pulmonary fibrosis development in COPD patients.
Atorvastatin attenuates TGF‑β1‑induced fibrogenesis by inhibiting Smad3 and MAPK signaling in human ventricular fibroblasts.
Sumoylation enhances the activity of the TGF-β/SMAD and HIF-1 signaling pathways in keloids.
Growth and Stem Cell Characteristics of Tendon-Derived Cells with Different Initial Seeding Densities: An In Vitro Study in Mouse Flexor Tendon Cells.
LncRNA MIAT/miR-133a-3p axis regulates atrial fibrillation and atrial fibrillation-induced myocardial fibrosis.
Downregulation of miR-96 suppresses the profibrogenic functions of cardiac fibroblasts induced by angiotensin II and attenuates atrial fibrosis by upregulating KLF13.
COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence.
Adipose‑derived mesenchymal stem cells ameliorate dibutyltin dichloride‑induced chronic pancreatitis by inhibiting the PI3K/AKT/mTOR signaling pathway.
Nrf2 in keratinocytes protects against skin fibrosis via regulating epidermal lesion and inflammatory response.
Blocking interleukin-6 trans-signaling protects against renal fibrosis by suppressing STAT3 activation.
Depletion of WNT10A Prevents Tumor Growth by Suppressing Microvessels and Collagen Expression.
Presence and function of stress granules in atrial fibrillation.
Stachydrine Ameliorates Cardiac Fibrosis Through Inhibition of Angiotensin II/Transformation Growth Factor β1 Fibrogenic Axis.
The Smad3-miR-29b/miR-29c axis mediates the protective effect of macrophage migration inhibitory factor against cardiac fibrosis.
Inhibition of Glutaminase 1 Attenuates Experimental Pulmonary Fibrosis.
The effect of topical ramipril and losartan cream in inhibiting scar formation.
SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition.
Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection.
Blockade of lncRNA-ASLNCS5088-enriched exosome generation in M2 macrophages by GW4869 dampens the effect of M2 macrophages on orchestrating fibroblast activation.
Novel role of the clustered miR-23b-3p and miR-27b-3p in enhanced expression of fibrosis-associated genes by targeting TGFBR3 in atrial fibroblasts.
Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.
Concentrated Growth Factors Can Inhibit Photoaging Damage Induced by Ultraviolet A (UVA) on the Human Dermal Fibroblasts In Vitro.
Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways.
Vascular smooth muscle cell-specific progerin expression in a mouse model of Hutchinson-Gilford progeria syndrome promotes arterial stiffness: Therapeutic effect of dietary nitrite.
The emerging roles of a novel CCCH-type zinc finger protein, ZC3H4, in silica-induced epithelial to mesenchymal transition.
Eliciting α7-nAChR exerts cardioprotective effects on ischemic cardiomyopathy via activation of AMPK signalling.
HBOA ameliorates CCl(4)-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways.
Nox1/4 dual inhibitor GKT137831 attenuates hypertensive cardiac remodelling associating with the inhibition of ADAM17-dependent proinflammatory cytokines-induced signalling pathways in the rats with abdominal artery constriction.
Neutralization of IL-18 by IL-18 binding protein ameliorates bleomycin-induced pulmonary fibrosis via inhibition of epithelial-mesenchymal transition.
Resveratrol Attenuates Pressure Overload-Induced Cardiac Fibrosis and Diastolic Dysfunction via PTEN/AKT/Smad2/3 and NF-κB Signaling Pathways.
Interleukin-9 blockage reduces early hepatic granuloma formation and fibrosis during Schistosoma japonicum infection in mice.
Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway.
LncRNA PCFL promotes cardiac fibrosis via miR-378/GRB2 pathway following myocardial infarction.
Anti-inflammatory effects of hederagenin on diabetic cardiomyopathy via inhibiting NF-κB and Smads signaling pathways in a type-2 diabetic mice model.
IMM-H007 improves heart function via reducing cardiac fibrosis.
Empagliflozin prevents cardiomyopathy via sGC-cGMP-PKG pathway in type 2 diabetes mice.
Calhex(231) Alleviates High Glucose-Induced Myocardial Fibrosis via Inhibiting Itch-Ubiquitin Proteasome Pathway in Vitro.
Catabolic changes of rat temporomandibular joint discs induced by unilateral anterior crossbite.
Liraglutide prevents β-cell apoptosis via inactivation of NOX2 and its related signaling pathway.
Inhibition of SIRT2 Alleviates Fibroblast Activation and Renal Tubulointerstitial Fibrosis via MDM2.
Flavonoid Extract from Propolis Inhibits Cardiac Fibrosis Triggered by Myocardial Infarction through Upregulation of SIRT1.
Critical in vivo roles of WNT10A in wound healing by regulating collagen expression/synthesis in WNT10A-deficient mice.
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
TGF-β1/Smad3 signaling promotes collagen synthesis in pulmonary artery smooth muscle by down-regulating miR-29b.
Antifibrotic Agent Pirfenidone Protects against Development of Radiation-Induced Pulmonary Fibrosis in a Murine Model.
Novel formononetin-7-sal ester ameliorates pulmonary fibrosis via MEF2c signaling pathway.
Role of miR-29 in mediating offspring lung phenotype in a rodent model of intrauterine growth restriction.
Glutaminolysis Promotes Collagen Translation and Stability via α-Ketoglutarate-mediated mTOR Activation and Proline Hydroxylation.
Overexpression of collagen type III in injured myocardium prevents cardiac systolic dysfunction by changing the balance of collagen distribution.
Circular RNA DLGAP4 Ameliorates Ischemic Stroke Outcomes by Targeting miR-143 to Regulate Endothelial-Mesenchymal Transition Associated with Blood-Brain Barrier Integrity.
Deep Coverage Tissue and Cellular Proteomics Revealed IL-1β Can Independently Induce the Secretion of TNF-Associated Proteins from Human Synoviocytes.
Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway.
Klotho gene-modified BMSCs showed elevated antifibrotic effects by inhibiting the Wnt/β-catenin pathway in kidneys after acute injury.
Retracted: 'Anti-fibrotic actions of Ghrelin by inhibition of the NADPH oxidase-ROS signaling pathway' by Qian Wang, Xin Sui, Rui Chen, Peiyong Ma, Tao Ding, Dianjun Sui, and Ping Yang.
Clinical and experimental pharmacology & physiology 2018 Aug;45(8):885
Thymoquinone protects against cardiac damage from doxorubicin-induced heart failure in Sprague-Dawley rats.
MDM2 Contributes to High Glucose-Induced Glomerular Mesangial Cell Proliferation and Extracellular Matrix Accumulation via Notch1.
Development of a new biodegradable operative clip made of a magnesium alloy: Evaluation of its safety and tolerability for canine cholecystectomy.
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.
Relaxin alleviates TGFβ1-induced cardiac fibrosis via inhibition of Stat3-dependent autophagy.
Crucial Role of miR-433 in Regulating Cardiac Fibrosis.
Su T, Lai S, Chen H
PloS one 2026;21(1):e0340664
PloS one 2026;21(1):e0340664
Elevated lactate production exacerbates PM2.5-induced pulmonary fibrosis by stabilizing TGF-β1.
Liu Z, Liu W, Wei H, Ping Y, Yu Z, Dong Z, Ren J, Zhang S, Liu S
Journal of advanced research 2026 May;83:299-314
Journal of advanced research 2026 May;83:299-314
RNF220 mediates K63-linked polyubiquitination of STAT3 and aggravates pathological cardiac hypertrophy.
Gao Y, Zhao Z, Chen X, Li N, Li Y, Guan J, Dai H
Cell death and differentiation 2026 May;33(5):945-958
Cell death and differentiation 2026 May;33(5):945-958
Combination of Hypoxia-Preconditioned ADSCs and Deferoxamine Can Speed Up the Healing of Diabetic Wounds by Promoting Angiogenesis and Regulating Macrophage Polarization.
Cai F, Chen W, Li Q, Chen S, Xu Y, Ren Y, Liu Y
Stem cell reviews and reports 2026 May;22(4):1811-1826
Stem cell reviews and reports 2026 May;22(4):1811-1826
Promotion of DFU Wound Healing via BRG1-COL16A1 Axis in Fibroblasts.
Wang P, Sun J, Wang Y, Ren B, Liu Y, Liu Y, Chen L, Yu L, Dai T, Yu L, Dong Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(26):e16687
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(26):e16687
Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery
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Peng H, Chen Z, Zhang Q, Zhang Y, Yang P, Gong J, Zhao A
Molecular medicine reports 2026 Mar;33(3)
Molecular medicine reports 2026 Mar;33(3)
Nanoparticles reveal permanent and reversible changes to lymph node biomechanics during inflammatory response.
Ramirez A, Sriram V, Abbouchi Y, Patolia R, Passaro E, Kaluzienski M, Maisel K
Biomaterials 2026 Mar;326:123648
Biomaterials 2026 Mar;326:123648
IL-11 Drives Dermal Fibroblast Activation in Mechanical Stretch-Mediated Skin Expansion.
Liu Y, Khoong YM, Xia W, Xu R, Widjaja AA, Liang H, Luo S, Yang E, Huang X, Zan T
The Journal of investigative dermatology 2026 Mar;146(3):743-757.e9
The Journal of investigative dermatology 2026 Mar;146(3):743-757.e9
Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles.
Xie X, Bi S, Su B, Zhou R, Li X, Yan Z, Zhou X, Wang F, Yu T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e17257
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e17257
Small-molecule LF3 alleviates angiotensin II-induced cardiac dysfunction via attenuating cardiac fibrosis.
Liu X, Zhang C, Jiang W, Wu J, Li G, Zhao J, Sun X, Huang J, Zhao L
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 9;
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 9;
Fibroblast growth factor-inducible 14 accelerates pulmonary fibrosis by inducing fibroblast senescence in mice.
Guan XX, Zhong WJ, Tang WF, Liu YB, Chen MR, Li JL, Zhang CY, Zhou Y, Guan CX, Wu JN, Ma L, Duan JX
Cellular and molecular life sciences : CMLS 2026 Mar 6;83(1)
Cellular and molecular life sciences : CMLS 2026 Mar 6;83(1)
Network medicine modeling of the m⁶A regulatory landscape identifies a KLF6-WTAP axis as a therapeutic target in pulmonary fibrosis.
Xu C, Zhou Z, Lin Y, Zhang S, Cai S, Li B, Wang Z
Journal of translational medicine 2026 Mar 5;24(1)
Journal of translational medicine 2026 Mar 5;24(1)
Single-cell chromatin accessibility landscape of cardiac non-myocytes identifies tissue repair program during heart regeneration.
Chen Z, Nie Y, Huang L, Zeng N, Gong J, Gao Y, Wen Q, Chen X, Ji X, Li Y, Lan T, Jiang L, Wang J, Xu J, Cao N
NPJ Regenerative medicine 2026 Mar 5;11(1)
NPJ Regenerative medicine 2026 Mar 5;11(1)
Fibroblast-derived BMP5 promotes tendon adhesion by inducing bone marrow mesenchymal stromal cells to differentiate into myofibroblasts.
Wang K, Li Y, Yang Y, Zhang P, Lu Y, Zhao J, Zhang X, Pang S, Hu J, Yin W, Guo Y, Wu J, Liu S
Journal of advanced research 2026 Mar 4;
Journal of advanced research 2026 Mar 4;
Upregulation of T-type voltage-dependent Ca²⁺ channels in activated hepatic stellate cells promotes liver fibrosis in metabolic dysfunction-associated steatohepatitis.
Kawata N, Kondo R, Hashizume M, Suzuki Y, Yamamura H
Pflugers Archiv : European journal of physiology 2026 Mar 31;478(4)
Pflugers Archiv : European journal of physiology 2026 Mar 31;478(4)
Sexual dimorphism in keratoconus: transcriptomic and hormonal mechanisms underlying stromal remodelling.
Sun Y, Li Q, Wu X, Yu X, Wang R, Sun B, Wang K, Yu Y, Chen S, Jiang D, Chen W
Eye and vision (London, England) 2026 Mar 3;13(1)
Eye and vision (London, England) 2026 Mar 3;13(1)
High-Intensity Interval Training Outperforms Moderate-Intensity Exercise in Hyperlipidemic ApoE⁻/⁻ Mice: A Molecular and Histological Comparison.
Qian C, Pei Z, Yang Z, Sun M, Zhang Y, Liu H, Sun Y
Frontiers in bioscience (Landmark edition) 2026 Mar 20;31(3):47751
Frontiers in bioscience (Landmark edition) 2026 Mar 20;31(3):47751
Dynamically responsive hydrogel with mechanical stimulation enhances diabetic wound healing via activation of Piezo1-mediated efferocytosis.
Tao Z, Li Z, Shao Y, Xiao Y, Fan X, Yang L, Sun Z, Cui T, Sun Z, Jiang J, Lian X, Guo X, Liu S, Ma X
Bioactive materials 2026 Jun;60:607-625
Bioactive materials 2026 Jun;60:607-625
Multi-omics and AI-guided discovery and validation of sisomicin as a COPA-targeting agent for pathological scar inhibition.
Li P, Luo Z, Ali M, Li J, Qi F
Burns : journal of the International Society for Burn Injuries 2026 Jun;52(5):108015
Burns : journal of the International Society for Burn Injuries 2026 Jun;52(5):108015
Rational design of FAP-targeted sEVs delivered by microneedles for precision treatment of hypertrophic scars via ferroptosis in hypertrophic scar fibroblasts.
Xu Y, Zhang Y, Sun Z, Gong J, Shen Q, Meng H, Liu X, Chen J, Hao Y, Xu Z, Ma K, Ma L, Guo K, Pan X, Fu X, Zhang C
Materials today. Bio 2026 Jun;38:103117
Materials today. Bio 2026 Jun;38:103117
Prostaglandin F2α impairs skin regeneration via FP receptor-mediated oxidative stress overriding autophagic protection in fibroblasts.
Wen Z, Guo Y, Bai R, Liu W, Liang B, Dong C, Zhang Y, Song Y, Wang T, Wang Z, Du J, Ma X, Ding J, Yu Z
Pathology, research and practice 2026 Jun;282:156467
Pathology, research and practice 2026 Jun;282:156467
SiO(2) dust induces the transformation of lung fibroblasts to myofibroblasts by activating the S1P-RhoA-YAP signaling pathway.
Zhang H, Huang F, Guan L, Zeng M
Toxicology in vitro : an international journal published in association with BIBRA 2026 Jun;114:106229
Toxicology in vitro : an international journal published in association with BIBRA 2026 Jun;114:106229
Inhibiting fibroblast activation protein mitigates aging-related periodontitis by blocking nuclear factor kappa B-mediated osteoclastogenesis.
Sun Y, Zou H, Cui A, Dong H, Pawuziya A, Zhao P, Wang J, Leung WK, Wang Q
International immunopharmacology 2026 Jun 15;179:116647
International immunopharmacology 2026 Jun 15;179:116647
Ailanthone ameliorates CCl(4)-induced liver fibrosis by targeting PKM2-mediated macrophage M1 polarization and glycolytic reprogramming.
Wan Y, Wang T, Wang K, Huo Q, Cheng X
International immunopharmacology 2026 Jun 15;179:116640
International immunopharmacology 2026 Jun 15;179:116640
FOSL1 mediates collagen synthesis and myofibroblast transformation in aortic fibroblasts under Ang II-induced aortic dissection conditions.
Zhong L, Zhang H, Huang Y, Zhang L, Zhang L, Liu Q, Liao Y, Zhang Q, Fu W, Wang C, Li X, Chen L, Li Y
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2026 Jun 1;221:107504
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2026 Jun 1;221:107504
CACNB2 overexpression suppresses atrial fibroblast activation and atrial fibrosis to mitigate atrial fibrillation.
Zhang D, Li Z, Li N, Zhang H
Cellular signalling 2026 Jul;143:112448
Cellular signalling 2026 Jul;143:112448
Dynamic expression of type III collagen in the lesion core of post-ischemic brain colocalizing with angiogenesis and lipid droplets during fibrotic scar formation.
Mutoh T, Kitajo K, Yamaguchi A
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 Jan;46(1):134-150
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 Jan;46(1):134-150
High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE(‑/‑) mice via the NAD(+)‑mediated SIRT1/MFN2 pathway.
Gao S, Yao W, Yang J, Liu Y, Pei Z
Molecular medicine reports 2026 Jan;33(1)
Molecular medicine reports 2026 Jan;33(1)
ACLP promotes hypertrophic scar pathogenesis by enhancing myofibroblast activation and cholesterol synthesis-related gene expression.
Shi Y, Song Y, Wang T, Jiao Y, Dang J, Zhang Y, Xiao S, Song B, Yu Z
Pathology, research and practice 2026 Jan;277:156311
Pathology, research and practice 2026 Jan;277:156311
QiShenYiQi dripping pills ameliorate post-myocardial infarction cardiac fibrosis via modulation of the cAMP/Rap1 and PI3K/Akt signaling pathways.
Liu Z, Chen S, Fu H, Li K, Liu H, Qin L, Wang L, Jin J, Yin L, Chen J
Fitoterapia 2026 Jan;188:107020
Fitoterapia 2026 Jan;188:107020
HNRNPC Promotes Keloid Progression by Modulating the Stability of N(6)-Methyladenosine-Modified WDR77 mRNA and Expression of TGF-β and SMAD3.
Zhan Y, Zeng N, Yu J, Wu Y, Zhu K, Yang Z, Guo X, Zhang Q, Liu Z
The Journal of investigative dermatology 2026 Jan;146(1):236-248.e6
The Journal of investigative dermatology 2026 Jan;146(1):236-248.e6
Reprogramming offspring liver health: maternal indole supplementation as a preventive strategy against MASLD.
Mandala A, Undi RB, Janssen RC, Sugino KY, Zhao W, Nelson BN, Teague AM, Patil NY, Zemsky Berry K, Varshney R, Bergman BC, Rudolph MC, Joshi AD, Rajala RVS, Jonscher KR, Friedman JE
EBioMedicine 2026 Jan;123:106098
EBioMedicine 2026 Jan;123:106098
Adolescent high fructose consumption induces cardiac dysfunction in adulthood via elevated histone acetylation.
Shen AN, Shi HQ, Zhang ZH, Yao Y, Zhao R, Shi Y, Zhao JY, Cai K, Wang F
Translational pediatrics 2026 Jan 31;15(1):13
Translational pediatrics 2026 Jan 31;15(1):13
A clinically translatable pathomics-based predictive model for preoperative prognostic assessment in patients with endometrial cancer.
Liu J, Zhao H, Zhang X, Liu L, Zhang L
Discover oncology 2026 Jan 16;17(1):283
Discover oncology 2026 Jan 16;17(1):283
Guiqi Yishen granule alleviates obstructive nephropathy-induced renal fibrosis by targeting PI3K/AKT signaling pathway.
Zhu J, Cao S, Wang T, Wang N, Yang L, Tang X, Jiang M, Zhu Q, Yu H, Wu D, Peng WX
Journal of ethnopharmacology 2026 Jan 10;354:120490
Journal of ethnopharmacology 2026 Jan 10;354:120490
BACH1 is stabilized by vitamin E and attenuates the formation of hypertrophic scar through the Wnt/β-catenin pathway.
Luan W, Fan S, Jiang H, Jiang D, Yang J, He L
Burns : journal of the International Society for Burn Injuries 2026 Feb;52(1):107807
Burns : journal of the International Society for Burn Injuries 2026 Feb;52(1):107807
Targeting Tumor Necrosis Factor-α Mitigates Glucose Fluctuation-Induced Aortic Valve Fibrosis: Insights From Diabetic Rat Models.
Chen YJ, Chen HP, Zhang CY, Rong XS, Li KL, Xiao F, Wang RX
Reviews in cardiovascular medicine 2026 Feb;27(2):42804
Reviews in cardiovascular medicine 2026 Feb;27(2):42804
Hepatic stellate cells shape the ECM-disorganized and immunosuppressive microenvironment via CCL11/CCR3 axis in lenvatinib-treated hepatocellular carcinoma.
Qiang N, Lan C, Lin A, Kanzaki H, Inoue M, Kanogawa N, Kondo T, Ogasawara S, Nakamura M, Nakamoto S, Cui D, Lv H, Xu Q, Chen G, Ao J
Cellular signalling 2026 Feb;138:112263
Cellular signalling 2026 Feb;138:112263
DOT1L promotes phenotypic transition of vascular smooth muscle cells following vascular injury in diabetes through activation of the FGFR4/PI3K/AKT/Jag/Notch signaling pathway.
Zhang J, Wu D, Cheng C, Yang Z, Chen Z, Liu L, Li W, Wang W, Huang C, Yang J
Cellular signalling 2026 Feb;138:112223
Cellular signalling 2026 Feb;138:112223
Lipid Nanoparticles Enable Efficient EGF mRNA Delivery for Wound Healing.
Zhou Q, Liu W, Ge J, Liu X, Wang H, Fu W, Deng D
Pharmaceutics 2026 Feb 9;18(2)
Pharmaceutics 2026 Feb 9;18(2)
Integrated metabolomics and 16S rRNA sequencing reveal the mechanism of total flavones of Abelmoschus manihot (L.) Medic against liver fibrosis.
Li D, Ge H, Zhang Y, Song S, Xing L, Tang EH, Wang F
Scientific reports 2026 Feb 5;16(1)
Scientific reports 2026 Feb 5;16(1)
Role of CTGF-LRP1 in impaired healing of cesarean section incisions.
He C, Ge S, Xia W, Wang Y, Yan L, Sun J, Yan L, Zhu Q, Zhao X, Zhang J
Nature communications 2026 Feb 28;17(1)
Nature communications 2026 Feb 28;17(1)
Prussian blue nanoparticles targeting multiple PANoptosome-mediated PANoptosis for myocardial ischemia-reperfusion injury therapy.
Xu L, Jiang L, Wu R, Yan H, Li B, Cai X, Zheng Y
Nature communications 2026 Feb 27;17(1)
Nature communications 2026 Feb 27;17(1)
Hydroxytyrosol Prevents Metabolic-Associated Steatohepatitis by Inhibiting SOCS2-Mediated Ferroptosis in High-Fat Diet Mice.
Yi D, Wu Z, Li X, Shao B, Xiao Y, Li T, Zhang X, Zhu J, Yang T, Deng Y, Huang T, Qiu T, Bai J, Shi X, Wu C, Wu Z, Sun X, Wang N
Journal of agricultural and food chemistry 2026 Feb 25;74(7):6265-6277
Journal of agricultural and food chemistry 2026 Feb 25;74(7):6265-6277
FGF2 rescues denervation-induced muscle atrophy in Ambystoma mexicanum.
Nakayama H, Ohashi A, Yamamoto S, Furukawa S, Satoh A
Skeletal muscle 2026 Feb 20;16(1)
Skeletal muscle 2026 Feb 20;16(1)
Nur77 Regulates the Phosphorylation of Smad3, Thereby Influencing Skeletal Muscle Fibrosis Caused by Obesity.
Li N, Tian T, Zhao Q, Wang D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 15;40(3):e71484
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 15;40(3):e71484
Gamma delta T cells promote intestinal fibrosis via an interleukin-17A-induced transforming growth factor-beta signaling pathway in fibroblasts.
Li Y, Chen M, Chen C, Huang B, Liu F, Liang D, Sun D, He Z, Lan C
Molecular immunology 2026 Apr;192:21-31
Molecular immunology 2026 Apr;192:21-31
Protective Effects of Agrimonia pilosa Ledeb. In Myocardial Fibrosis: Inhibition of Mitophagy Mediated by the FOXO Signaling Pathway.
Chen J, Wei Z, An J, Li D, Gu Y, Zhang Y, Zhang M
Food science & nutrition 2026 Apr;14(4):e71778
Food science & nutrition 2026 Apr;14(4):e71778
The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis.
Guo S, Wang Y, Lu B, Zhang Y, Frazer DM, Zhou B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e16446
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e16446
Loss of PTH 1 receptor signaling in periodontal cells drives cementum dysfunction and molar ankylosis in mice.
Turkkahraman H, Walton CJ, Zhu T, Akel N, Marino S, Yuan X, Bellido TM
Bone research 2026 Apr 27;14(1)
Bone research 2026 Apr 27;14(1)
18-β-glycyrrhetinic acid facilitates nuclear-mitochondrial communications to alleviate oxidative stress through HMGB1-cGAS-Mul1 axis in tendinopathy.
Gao YY, Sun WS, Sun ZY, Wang JR, Lv ZY, Li YJ, Tian HY, Bao ZY, Qiu XR, Wang Z, Zheng SZ, Shao JJ, Zhang ZL, Meng J
Journal of translational medicine 2026 Apr 17;24(1)
Journal of translational medicine 2026 Apr 17;24(1)
Neddylation of STAT3 is a potential therapeutic target for MASLD.
Liu F, Zhao F, Du M, Ma J, Shang Y, Liu Z, Zhu Y, Zhang Z, Xie P
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 15;1872(6):168261
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 15;1872(6):168261
GPR30-mediated NETs degradation via Trex1 in heart failure of aged female mice.
Zhang S, Li Z, Wang X, Wang X, Du J, Liu J, Cheng Z, Zhao D, Duan W, Ma J, Liu J
Journal of translational medicine 2026 Apr 11;24(1)
Journal of translational medicine 2026 Apr 11;24(1)
Salidroside ameliorates skin aging in male mice by promoting collagen regeneration via modulation of FOS and MMP9.
Wang Z, Yan X, Li X, Zhu H, Wang Y, Fan X, Lu X, Li X, Yang M, Zhang C, Wu Y
Biogerontology 2026 Apr 10;27(3)
Biogerontology 2026 Apr 10;27(3)
Integrated transcriptome and proteome analysis identifies keratins as key regulators of corneal scarring in a murine model.
Zhou T, Cai Y, Fang F, Cai X, Fu Y
Computational and structural biotechnology journal 2025;27:2264-2274
Computational and structural biotechnology journal 2025;27:2264-2274
TAGLN-RhoA/ROCK2-SLC2A3-mediated Mechano-metabolic Axis Promotes Skin Fibrosis.
Cheng X, Gao Z, Zhang J, Zheng H, Shan S, Zhou J
International journal of biological sciences 2025;21(2):658-670
International journal of biological sciences 2025;21(2):658-670
Inhibition of Mettl3 alleviates low-dose cisplatin-induced renal fibrosis and enhances the chemotherapeutic efficacy in mouse models of cancer.
Xie Y, Li H, Pan J, Li Y, Zhang D
International journal of biological sciences 2025;21(10):4293-4311
International journal of biological sciences 2025;21(10):4293-4311
Mechanical stretch-induced IGF2 overexpression in epidermal keratinocytes promotes hypertrophic scar formation through the IGF1R/p-c-Jun axis.
Zhu Y, Chen L, Song B, Cui Z, Chen G, Dou W, Jiao Y, Dang J, Yang Q, Yu Z, Song B
International journal of biological sciences 2025;21(1):109-127
International journal of biological sciences 2025;21(1):109-127
Fibroblast Activation Protein-Targeted CAR-T Cells Induce Apoptosis in Murine Cardiac Myofibroblasts.
Li H, Zheng Q, Jiang Y, Yang L, Li S, Yang P, Yin G, Sun L
Cardiovascular therapeutics 2025;2025:7230505
Cardiovascular therapeutics 2025;2025:7230505
Overexpression of Decorin Optimizes the Treatment Efficacy of Umbilical Cord Mesenchymal Stem Cells in Bleomycin-Induced Pulmonary Fibrosis in Rats.
Zhi Y, Shu M, Tang P, Li Y, Guo M, Deng J, Mo H, Wu M, Liu B, Mai Y, Ling J, Zhao X, Zhang X, Zuo W
Stem cells international 2025;2025:6324980
Stem cells international 2025;2025:6324980
NIR-II Imaging Guided Accurate Identification of Paraspinal Muscle Degeneration Through Targeting the Lysosomal Membrane Protein Sidt2.
Piao G, Fan L, Zhang Y, Jiang W, Guo X, Liu R, Wang Q, Jia S, Liang J, Li Y
International journal of nanomedicine 2025;20:7743-7762
International journal of nanomedicine 2025;20:7743-7762
A Critical Role for the Mitochondrial Pyruvate Carrier in Hepatic Stellate Cell Activation.
Habibi M, Ferguson D, Eichler SJ, Chan MM, Fu C, Pietka TA, Bredemeyer AL, LaPoint A, Shew TM, He M, Liss KHH, Lutkewitte AJ, Cho K, Schilling JD, Patti GJ, Finck BN
Cellular and molecular gastroenterology and hepatology 2025;19(8):101517
Cellular and molecular gastroenterology and hepatology 2025;19(8):101517
Pro-inflammatory cytokines disrupt in vitro preantral follicle development by targeting granulosa and theca cell functions.
Shirafuji A, Orisaka M, Shimizu-Mizuno N, Uesaka M, Fujita Y, Mizuno K, Fujita M, Miyazaki Y, Onuma T, Tsuyoshi H, Mizutani T, Yoshida Y
Frontiers in endocrinology 2025;16:1667019
Frontiers in endocrinology 2025;16:1667019
Targeted ferroptosis of myofibroblasts by tubeimoside I attenuates hypertrophic scar formation.
Wang J, Wang C, Jia Y, Chen F, Wang Y, Du J
Frontiers in pharmacology 2025;16:1654108
Frontiers in pharmacology 2025;16:1654108
Isorhamnetin attenuates renal interstitial fibrosis by targeting TWEAK/Fn14-mediated epithelial-mesenchymal transition.
Chen Y, Luo W, Guan H, Chen Z, Chen Z, Xiao L, Xu W, Huang M, Lin Y, Zhang Y, Peng W, Nan L
Frontiers in immunology 2025;16:1649327
Frontiers in immunology 2025;16:1649327
Synergistic effects of retinol and retinyl palmitate in alleviating UVB-induced DNA damage and promoting the homologous recombination repair in keratinocytes.
Zhong J, Liang L, Zhao N, Wang J, Shu P
Frontiers in pharmacology 2025;16:1562244
Frontiers in pharmacology 2025;16:1562244
Mechanical stress contributes to ligamentum flavum hypertrophy by inducing local inflammation and myofibroblast transition in the innovative surgical rabbit model.
Ma Q, Feng X, Chen Y, Zhang J, Sun C
Frontiers in immunology 2025;16:1541577
Frontiers in immunology 2025;16:1541577
Roles of retinoic acid-related orphan receptor α in high glucose-induced cardiac fibroblasts proliferation.
San W, Zhou Q, Shen D, Cao D, Chen Y, Meng G
Frontiers in pharmacology 2025;16:1539690
Frontiers in pharmacology 2025;16:1539690
Single-cell RNA sequencing reveals that myeloid S100A8/A9 is a novel regulator of the transition from adaptive hypertrophy to heart failure after pressure overload.
Yu WJ, Jiang WX, Liu SJ, Li HH, Lin QY
Theranostics 2025;15(16):8587-8608
Theranostics 2025;15(16):8587-8608
The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation.
Ren X, Wang Z, Wang J, Li X, Wei H, Liu C, Liu S, Zhu Y, Feng C, Yin Y, Tian Y, Wu M, Zeng X
ImmunoTargets and therapy 2025;14:151-173
ImmunoTargets and therapy 2025;14:151-173
Receptor activity-modifying protein 1 regulates the differentiation of mouse skin fibroblasts by downregulating α-SMA expression via suppression of high mobility group AT-hook 1 to promote skin wound repair.
Song R, Ma J, Yin S, Wu Z, Liu C, Sun R, Cao G, Lu Y, Liu J, Su L, Wang Y
Burns & trauma 2025;13:tkae068
Burns & trauma 2025;13:tkae068
Decoding HuH-7: a comprehensive genetic and molecular portrait of a widely used hepatocellular carcinoma model.
Luis DD, Liehr T, Kankel S, Weise A, Pentzold C, Buhl EM, Hardt KS, Keller DT, Schröder-Lange SK, Weiskirchen R
Frontiers in cell and developmental biology 2025;13:1648639
Frontiers in cell and developmental biology 2025;13:1648639
Restoration of tendon repair microenvironment by grapefruit exosome-loaded microneedle system for tendinopathy therapy.
Zhang Y, Zhang R, Zhang T, Mu Y, Juma T, Li X, Li H, Guo Q, Cao Y
Frontiers in bioengineering and biotechnology 2025;13:1615650
Frontiers in bioengineering and biotechnology 2025;13:1615650
Saliva-derived exosomes regulate fibroblast metabolic reprogramming in skin wound healing.
Song S, Xiang R, Chen S, Wu J, Chen W, Li X
Frontiers in cell and developmental biology 2025;13:1606716
Frontiers in cell and developmental biology 2025;13:1606716
The endogenous glutamatergic transmitter system promotes collagen synthesis in cardiac fibroblasts under hypoxia.
Wang R, Yuan X, Xie T, Zhao X, Li J, Zhang X, Lv C
Frontiers in cardiovascular medicine 2025;12:1638650
Frontiers in cardiovascular medicine 2025;12:1638650
Rapid cutaneous wound healing in nude mice by fetal skin-derived stem cells involves enhanced collagen secretion and angiogenesis.
Geng Y, Zhang W, Dun X, Wang Y, Shao Y
Frontiers in medicine 2025;12:1557973
Frontiers in medicine 2025;12:1557973
Photocrosslinkable hydrogel of kartogenin functionalized chitosan methacrylate preserves chondrogenesis.
Ding Y, Zhu J, Guan X, Li C, Cai P, Lu C, Song L, Wu J
International journal of biological macromolecules 2025 Sep;321(Pt 3):146378
International journal of biological macromolecules 2025 Sep;321(Pt 3):146378
Novel partial common bile duct ligation procedure in rats with reduced mortality and delayed onset of cirrhosis.
Xia W, Yao H, Mu T, Liu H, Chen J, Feng S, Wen S
Experimental and therapeutic medicine 2025 Sep;30(3):167
Experimental and therapeutic medicine 2025 Sep;30(3):167
Parathyroid glands exhibit reduced parenchymatic chief cells and increased extracellular collagen as a response to a long-term low-phosphorus diet in pigs.
Oster M, Reyer H, Hadlich F, Ponsuksili S, Wolf P, Wimmers K, Keiler J
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Sep;22:471-482
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Sep;22:471-482
5-Aminolevulinic acid-mediated photodynamic therapy improves scar healing of laryngeal wounds in rats.
Li J, Lu Y, Hu H, Han X, Pan Y, Sun K, Liu K, Yu Z
Lasers in medical science 2025 Sep 9;40(1):353
Lasers in medical science 2025 Sep 9;40(1):353
TGF-β-mediated epithelial-mesenchymal transition of keratinocytes promotes fibrosis in secondary lymphedema.
Park HJ, Shin J, Sarker A, Klang MG, Riedel E, Coriddi M, Dayan JH, Pal S, Mehrara BJ, Kataru RP
JCI insight 2025 Sep 9;10(17)
JCI insight 2025 Sep 9;10(17)
Chrysin inhibits hypertrophic scar formation through TGF-β/Smad signaling pathways.
Shen L, Chen L, Yang J, Liu C, Liao H, Yu Q, Wen X, Yang Y
Journal of molecular histology 2025 Sep 6;56(5):298
Journal of molecular histology 2025 Sep 6;56(5):298
HSF2 drives breast cancer progression by acting as a stage-specific switch between proliferation and invasion.
Pessa JC, Paavolainen O, Hästbacka HSE, Puustinen MC, Da Silva AJ, Pihlström S, Gramolelli S, Boström P, Hartiala P, Peuhu E, Joutsen J, Sistonen L
Science advances 2025 Sep 5;11(36):eady1289
Science advances 2025 Sep 5;11(36):eady1289
A two-stage transdermal drug delivery system comprising sono-phase-change transfersomes for non-invasive deep dermal delivery.
Zhang Y, He X, Mao X, Yang Y, Li F, Han X, Lu H, Tang L, Yang Y, Wang Y, Du Y, Xu W, Wang Z
Journal of nanobiotechnology 2025 Sep 29;23(1):621
Journal of nanobiotechnology 2025 Sep 29;23(1):621
Unraveling the therapeutic mechanisms of Bufei Yiqi decoction in pulmonary fibrosis: Modulation of autophagy and glycolysis pathways.
Chen H, Zhang Z, Song Y, Hu Q, Jin D, Liu S, Zu J, Zhang L, Ke M, Chen L, Hu A
International immunopharmacology 2025 Sep 23;162:115030
International immunopharmacology 2025 Sep 23;162:115030
Colla Corii Asini regulate collagen regeneration in UV exposure-induced skin photoaging in mice.
Ma Y, Huang J, Gong J, Li L, Zhao Y, Jin Y, Gu J, Liu H, Wang Y, Sun Y
Chinese medicine 2025 Sep 22;20(1):146
Chinese medicine 2025 Sep 22;20(1):146
JunB orchestrates macrophage-fibroblast crosstalk in silica nanoparticle-induced pulmonary fibrosis.
Li F, Song D, Meng J, Tian J, Li N, Zheng Y, Zhang Z, Yun X, Li Z, Sun H, Zhang L, Shen F
Ecotoxicology and environmental safety 2025 Sep 15;303:119046
Ecotoxicology and environmental safety 2025 Sep 15;303:119046
Canagliflozin-driven cellular re-differentiation and migration inhibition in vascular smooth muscle cells via PTEN upregulation.
Hsieh MJ, Chen DY, Lee CH, Liao YC, Lin MS, Pang JS
Naunyn-Schmiedeberg's archives of pharmacology 2025 Oct;398(10):14487-14500
Naunyn-Schmiedeberg's archives of pharmacology 2025 Oct;398(10):14487-14500
Engineered decellularized tendon hydrogel with sustained zinc ion release orchestrates anti-inflammatory microenvironment and functional regeneration in Achilles tendinopathy.
Gao X, Wu S, Yao Z, Shao Y, Feng J, Yuan Z, Mao H
Materials today. Bio 2025 Oct;34:102104
Materials today. Bio 2025 Oct;34:102104
High-Yield Extruded Nanovesicles From Adipose Stem Cells Promote High-Quality Healing of Diabetic Wound Through WNT/β-Catenin Pathway Activation.
Yao T, Liu L, Miao Y, Li X, Yu Y, Sun R, Zhang Y, Cui L, Ma X
Journal of cellular and molecular medicine 2025 Oct;29(19):e70877
Journal of cellular and molecular medicine 2025 Oct;29(19):e70877
Cathepsin S Contributes to Bladder Fibrosis Following Bladder Outlet Obstruction via IL-6 Trans-signaling.
Yang M, Liu X, Wang H, Shen T, Wang L
Frontiers in bioscience (Landmark edition) 2025 Oct 31;30(10):45355
Frontiers in bioscience (Landmark edition) 2025 Oct 31;30(10):45355
Design and Synthesis of Senescence-Targeted Prodrugs with Senomorphic and Senolytic Properties To Mitigate Chemotherapy-Induced Kidney Injury.
Ding L, Wang X, Liu Q, Zhang Y, Wu X, Xiao B, Liu D, Chen L, Zeng H, Zhao B, Dong C, Li L, Ge G, Jia L, Ni S
Journal of medicinal chemistry 2025 Oct 23;68(20):21458-21478
Journal of medicinal chemistry 2025 Oct 23;68(20):21458-21478
Mitochondrial one-carbon metabolism is required for TGF-β-induced glycine synthesis and fibrotic responses.
Meliton AY, Shin KWD, Cetin-Atalay R, Atalay MV, Tian Y, Houpy Szafran JC, Cho T, Sun KA, Woods PS, Shamaa OR, Chen B, Dulin NO, Husain AN, Muir A, Shah H, Mutlu GM, Hamanaka RB
Nature communications 2025 Oct 20;16(1):9250
Nature communications 2025 Oct 20;16(1):9250
Reduced expression of PDZK1 mediates fibroblast activation and cardiac fibrosis via EGFR phosphorylation in diabetic cardiomyopathy.
Cheng Y, Wang Y, Yin R, Xu Y, Xu Y, Lang J, Wei L, Zhang Y, Ke J, Zhao D, Yang L
Life sciences 2025 Oct 15;379:123916
Life sciences 2025 Oct 15;379:123916
l-cysteine rescues radiation induced ferroptosis and boosts wound healing through fibroblasts proliferation and migration.
Yang M, Huang C, Luo W, Gong P, Huang B, Yao Y
Biochemical and biophysical research communications 2025 Oct 10;784:152599
Biochemical and biophysical research communications 2025 Oct 10;784:152599
Porous chitin nanofibers combined with adipose-derived stem cells promote diabetic wound healing via PPAR-γ activation.
Zhang Z, Zheng Y, Wang Z, Li Y, Liu Y, Luo Z
International journal of biological macromolecules 2025 Nov;330(Pt 1):147763
International journal of biological macromolecules 2025 Nov;330(Pt 1):147763
BCAA exaggerated acute and chronic ischemic heart disease through promotion of NLRP3 via Sirt1.
Peng Y, Duan Y, Wang D, Liu J, Zhao G, Ji Z, Zhang J, Wei B
Biochemical pharmacology 2025 Nov;241:117150
Biochemical pharmacology 2025 Nov;241:117150
Comprehensive analysis of extracellular matrix remodelling via cyclophilin inhibition in human models of alcohol-related liver fibrosis.
Rastovic U, Campinoti S, Wei L, Almeida B, Bozzano SF, Amiri R, Harris N, Ajayi O, Koay TS, Kerins C, Kenny FN, Zamalloa A, Adofina L, Miquel R, Zen Y, Srinivasan P, Menon K, Heaton N, Luni C, Gentleman E, Shaw T, Ure D, Chokshi S, Urbani L, Palma E
British journal of pharmacology 2025 Nov;182(22):5647-5669
British journal of pharmacology 2025 Nov;182(22):5647-5669
The total xanthones from Gentianella acuta alleviate acute myocardial infarction by targeting BRD4-mediated cardiomyocyte pyroptosis and inflammation.
Dai C, Sun J, Yang G, Zhang C, Zhang Y, Song Q, Liu X, Duan X, Yang H, Li A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157156
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157156
The Composite Antiadhesion Barrier Facilitated Fibroblast Autophagy Activation for Tendon Repair.
Sun Z, Liu J, Chen L, Wang Z, Wang F, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e06204
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e06204
Mechanistic effects of percutaneous needle fasciotomy combined with stretching on early-stage skeletal muscle fibrosis in rats: focus on the TGF-β1/Smad signaling pathway.
Zhang H, Li W, Zhang H, Lu M, Zhao X, Li J, Hu R, Zhang Y
Journal of orthopaedic surgery and research 2025 Nov 7;20(1):978
Journal of orthopaedic surgery and research 2025 Nov 7;20(1):978
Ustekinumab enhances intestinal stenosis resolution by modulating fibrotic pathways in crohn's disease: a retrospective single-center study with translational analysis.
Nakata R, Hosomi S, Kobayashi Y, Nishida Y, Maruyama H, Ominami M, Nadatani Y, Fukunaga S, Otani K, Kamata N, Tanaka F, Fukuoka T, Maeda K, Fujiwara Y
BMC gastroenterology 2025 Nov 5;25(1):785
BMC gastroenterology 2025 Nov 5;25(1):785
From Gene to Scar: Proteome-Wide Causal Insights into Keloid Pathogenesis and Prevention.
Xu Y, Liu JC, Jiang Z, Zhang J, He R, Wan M, Zhao S
Advances in wound care 2025 Nov 5;
Advances in wound care 2025 Nov 5;
BNC2 as a novel driver of pancreatic cancer progression through transcriptional regulation of COL3A1 and epithelial-to-mesenchymal transition.
Li X, Yu T, Yu Z, Zou X, He J, Wang D, Shen X, Liu S, Liu B
Medical oncology (Northwood, London, England) 2025 Nov 21;43(1):11
Medical oncology (Northwood, London, England) 2025 Nov 21;43(1):11
Lysyl Oxidases Are Necessary for Myometrial Contractility and On-time Parturition in Mice.
Ouellette A, Do C, Cohn-Guthrie S, Lam YW, Mahendroo M, Nallasamy S
Journal of the Endocrine Society 2025 May;9(5):bvaf028
Journal of the Endocrine Society 2025 May;9(5):bvaf028
Targeting PIM1 by Bruceine D attenuates skin fibrosis via myofibroblast ferroptosis.
Wang J, Song Y, Tan X, Wang T, Shi Y, Xu X, Du J, Yu Z, Song B
Redox biology 2025 May;82:103619
Redox biology 2025 May;82:103619
Collagen fiber and cellular dynamics of axolotl skin with aging.
Shima C, Ohashi A, Furukawa S, Yamamoto S, Kashimoto R, Satoh A
Development, growth & differentiation 2025 May;67(4):195-204
Development, growth & differentiation 2025 May;67(4):195-204
SIRT1 Alleviates Oxidative Stress-Induced Mitochondrial Dysfunction and Mitochondria-Associated Membrane Dysregulation in Stress Urinary Incontinence.
Chen L, Tang J, Zuo X, Li B, Liu C, Hong S, Min J, Hu M, Li S, Zhou M, Chen M, He Y, Xiao Y, Huang X, Hong L
Cell proliferation 2025 May;58(5):e70009
Cell proliferation 2025 May;58(5):e70009
Single-cell and spatial RNA sequencing identify divergent microenvironments and progression signatures in early- versus late-onset prostate cancer.
Cheng Y, Liu B, Xin J, Wu X, Li W, Shang J, Wu J, Zhang Z, Xu B, Du M, Cheng G, Wang M
Nature aging 2025 May;5(5):909-928
Nature aging 2025 May;5(5):909-928
LA-peptide Hydrogel-Regulation of macrophage and fibroblast fates and their crosstalk via attenuating TGF-β to promote scarless wound healing.
Li Z, Zhang L, Wang Y, Zhu Y, Shen H, Yuan J, Li X, Yu Z, Song B
Bioactive materials 2025 May;47:417-431
Bioactive materials 2025 May;47:417-431
Engrailed-1 inactivation leads to scarless skin wound healing through extracellular matrix remodeling.
Hao A, Dong X, Gou Y, Li A, Li J, Xiang H, Rahaman S, Zhu Y, Zhang H, You W, Shen G, Luo C, Mei O, Wu X, Shi LL, Reid RR, He TC, Fan J
Genes & diseases 2025 May;12(3):101484
Genes & diseases 2025 May;12(3):101484
From Invaginating Site to Deep Lesion: Spatial Transcriptomics Unravels Ectopic Endometrial Penetration Features in Adenomyosis.
Li B, Qi J, Cao Y, Long Y, Wei Z, Wang WS, Hu S, Wang Y, Zhu Q, Hu X, Sun Z, Zhu J, Ye T, Yao Y, Meng Y, Bian X, Dong X, Guan H, Huang Y, Sun Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2411752
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2411752
Enhancing Tendon Regeneration: Investigating the Impact of Topography on the Secretome of Adipose-Derived Stem Cells.
Long Q, Liu C, Zheng H, Wang M, Liu H, Liu Y, Cao Z, Sun Y, Mo Q, Backman LJ, Zhu J, Hu L, Huang J, Zhang W, Chen J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(18):e2417447
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(18):e2417447
CILP1 interacting with YBX1 promotes hypertrophic scar formation by suppressing PPARs transcription.
Wang J, Du J, Song Y, Tan X, Wu J, Wang T, Shi Y, Xu X, Yu Z, Song B
Cell death & disease 2025 May 9;16(1):371
Cell death & disease 2025 May 9;16(1):371
GSTP1 inhibits angiotensin II-induced atrial fibrillation by regulating ferroptosis.
Li H, Feng Z, Li B, Bai J, Lin QY, Yu X, Zhang N, Xie Y, Yang X
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2025 May 7;27(5)
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2025 May 7;27(5)
Transcriptional Study of Radiofrequency Device Using Experimental Mouse Model.
Li X, Wang Z, Li X, Fan X, Lu X, Li Y, Pan Y, Zhu Z, Zhu M, Li W, Chan L, Yu S, Pan Y, Wu Y
International journal of molecular sciences 2025 May 7;26(9)
International journal of molecular sciences 2025 May 7;26(9)
Pulmonary Injury Induced via Metal-Organic Frameworks (MOFs): ROS Generation and Inflammatory Responses Mediated by HKUST-1.
Zhang Y, Xue Z, Yang Z, Chen M, Zhou L, Zhou L, Zhu M, Huang Z, Li Y, Kang S, Zheng L, Zhang D
ACS omega 2025 May 6;10(17):17865-17874
ACS omega 2025 May 6;10(17):17865-17874
Serum-free endothelial cell culture medium for vascular smooth muscle cells sheet formation.
Yang J, Sun X, Jiang H, Li J, Liang J, Lin Z
Journal of biological engineering 2025 May 28;19(1):51
Journal of biological engineering 2025 May 28;19(1):51
Superoxide Anion (O(2)(-•)) Leading to Pulmonary Toxicity of Metal-Organic Frameworks (MOFs).
Zhang Y, Zhang Y, Yang Z, Xue Z, Zhou L, Chen M, Zhu M, Wu Q, Li Y, Kang S, Zheng L, Zhang D
Langmuir : the ACS journal of surfaces and colloids 2025 May 27;41(20):12510-12519
Langmuir : the ACS journal of surfaces and colloids 2025 May 27;41(20):12510-12519
Mesenchymal stem cell exosomes regulate TGFβ/Smad3 by decreasing the METTL3-NEAT1 axis to inhibit scar progression after breast surgery.
Du J, Wu J, Song Q, Li S, Hong Y, Anwar A, Fu Q, Liu J
Journal of molecular histology 2025 May 20;56(3):161
Journal of molecular histology 2025 May 20;56(3):161
Aggressive characteristics of tumor deposits in colorectal cancer highlight the need for staging refinement in patients with 0-3 metastatic lymph nodes.
Hu X, Xie S, Yang Z, Zhao X, Gong L, Yang P, Yang L, Wang S, Bao G, He X
International journal of cancer 2025 May 1;156(9):1826-1839
International journal of cancer 2025 May 1;156(9):1826-1839
Exploring the mechanism of tiRNA-Val-CAC-002 in the pathogenesis of oral submucous fibrosis.
Zeng L, Peng H, Sun L, Yu H, Wu Y
Journal of oral biosciences 2025 Mar;67(1):100588
Journal of oral biosciences 2025 Mar;67(1):100588
Bone Marrow Aspirate Concentrate Combined With an Appropriate Carrier Effectively Promotes Bone-Tendon Interface Healing in a Rabbit Model of Chronic Rotator Cuff Tear.
Han SC, Han J, Kim YK, Hyun MJ, Jeong HJ, Oh JH
The American journal of sports medicine 2025 Mar;53(3):600-611
The American journal of sports medicine 2025 Mar;53(3):600-611
LINC00525 promotes cell proliferation and collagen expression through feedforward regulation of TGF-β signaling in hypertrophic scar fibroblasts.
Chen L, Yin Y, Li J, Li Q, Zhu Z, Li J
Burns : journal of the International Society for Burn Injuries 2025 Mar;51(2):107353
Burns : journal of the International Society for Burn Injuries 2025 Mar;51(2):107353
Lnc PVT1 facilitates TGF-β1-induced human cardiac fibroblast activation in vitro and ISO-induced myocardial fibrosis in vivo through regulating MYC.
Wang J, Lv ZY, Li P, Zhang Y, Li X, Shen DF
Molecular and cellular biochemistry 2025 Mar;480(3):1611-1625
Molecular and cellular biochemistry 2025 Mar;480(3):1611-1625
Ergothioneine Ameliorates Liver Fibrosis by Inhibiting Glycerophospholipids Metabolism and TGF-β/Smads Signaling Pathway: Based on Metabonomics and Network Pharmacology.
Mao Y, Xie Z, Zhang X, Fu Y, Yu X, Deng L, Zhang X, Hou B, Wang X, Ma M, Ren F
Journal of applied toxicology : JAT 2025 Mar;45(3):514-530
Journal of applied toxicology : JAT 2025 Mar;45(3):514-530
Mitochondrial NAD(+) deficiency in vascular smooth muscle impairs collagen III turnover to trigger thoracic and abdominal aortic aneurysm.
Zhang J, Tang Y, Zhang S, Xie Z, Ma W, Liu S, Fang Y, Zheng S, Huang C, Yan G, Abudupataer M, Xin Y, Zhu J, Han W, Wang W, Shen F, Lai H, Liu Y, Ye D, Yu FX, Xu Y, Pan C, Wang C, Zhu K, Zhang W
Nature cardiovascular research 2025 Mar;4(3):275-292
Nature cardiovascular research 2025 Mar;4(3):275-292
Shenmai Injection Reduces Cardiomyocyte Apoptosis Induced by Doxorubicin through miR-30a/Bcl-2.
Zhang XN, Li YY, Lyu SC, Jia QJ, Zhang JP, Liu LT
Chinese journal of integrative medicine 2025 Mar;31(3):240-250
Chinese journal of integrative medicine 2025 Mar;31(3):240-250
CD39 Contributes to the Ability of Cell Invasion in Heterogeneity of Colorectal Cancer.
Li X, Shen Y, Lang J, Wu J, Qian Z, Shen G, Shen Y
Journal of cellular and molecular medicine 2025 Mar;29(5):e70486
Journal of cellular and molecular medicine 2025 Mar;29(5):e70486
Anti-fibrosis effect and its mechanism of atractylenolide III on post-traumatic extending knee joint contracture in rats.
Zhang BB, Xu L, Zhang QB, Wang Y, Chen C, Zhang JN, Rao XL, Zhu BJ, Li XM, Zhu DT, Kan XL, Mao J, Zhang R, Zhou Y
Experimental gerontology 2025 Mar;201:112708
Experimental gerontology 2025 Mar;201:112708
Connexin 43 dephosphorylation mediates the Dchs1/YAP/TEAD signaling pathway to induce cardiac fibrosis.
Wang M, Li W, Shao Y, Wang F, Huang Y, Wei C, Li P, Sun K, Yan X, Gou Z
Biochimica et biophysica acta. Molecular cell research 2025 Mar;1872(3):119919
Biochimica et biophysica acta. Molecular cell research 2025 Mar;1872(3):119919
Ubiquitin-specific peptidase 10 promotes renal interstitial fibrosis progression through deubiquitinating and stabilizing P53 protein.
Liu S, Yang Y, Li Q, Yu L, Zong Z, Zang R, Ji W, Sun S
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167660
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167660
Intravenous injection of PCSK9 gain-of-function mutation in C57BL/6J background mice on Angiotensin II-induced AAA.
Xu X, Li X, Zhai C, Yao Y, Li X, Ming C, Sun J, Wang H, Mao Y, Zhang L
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167657
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167657
The role of fibromodulin in myocardial fibrosis in a diabetic cardiomyopathy rat model.
Dai X, Yang F, Chen D, Yang L, Dong Z, Chen C, Xiao J
FEBS open bio 2025 Mar;15(3):436-446
FEBS open bio 2025 Mar;15(3):436-446
Ultrasound-Triggered Oxygen Release System for Accelerating Wound Healing of Diabetic Foot Ulcers.
Zhuge D, Yang S, Pan X, Xiao Y, Wang X, Wang W, Gao W, Lu A, Shi B, Chen B, Zhao Y
Advanced healthcare materials 2025 Mar;14(6):e2403224
Advanced healthcare materials 2025 Mar;14(6):e2403224
Targeting the E Prostanoid Receptor EP4 Mitigates Cardiac Fibrosis Induced by β-Adrenergic Activation.
Xu H, Mao X, Wang Y, Zhu C, Liang B, Zhao Y, Zhou M, Ye L, Hong M, Shao H, Wang Y, Li H, Qi Y, Yang Y, Chen L, Guan Y, Zhang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2413324
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2413324
Extracellular Mitochondrial-Derived Vesicles Affect the Progression of Diabetic Foot Ulcer by Regulating Oxidative Stress and Mitochondrial Dysfunction.
Zhang H, Yan Z, Zhu J, Li Z, Chen L, Zheng W, Dai Z, Yang J, Yun X, Wang Y, Zhou H, Jiang Z, Yu Q, Li S, Huang W, Yang L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2407574
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2407574
M2 macrophages promote PKM2 production in fibroblasts to alleviate UVB-induced photoaging.
Jia S, Shi N, Lu M, Wang X, Qi Y, Wang X, Zhao J, Jiang D
Cell cycle (Georgetown, Tex.) 2025 Mar-Apr;24(5-8):86-102
Cell cycle (Georgetown, Tex.) 2025 Mar-Apr;24(5-8):86-102
CDC20 protects the heart from doxorubicin-induced cardiotoxicity by modulating CCDC69 degradation.
Feng Z, Zhang N, Wang L, Guan X, Xie Y, Xia YL
Cellular & molecular biology letters 2025 Mar 5;30(1):29
Cellular & molecular biology letters 2025 Mar 5;30(1):29
Butyrate Ameliorates Graves' Orbitopathy Through Regulating Orbital Fibroblast Phenotypes and Gut Microbiota.
Ouyang P, Qi J, Tong B, Li Y, Cao J, Wang L, Niu T, Qi X
Investigative ophthalmology & visual science 2025 Mar 3;66(3):5
Investigative ophthalmology & visual science 2025 Mar 3;66(3):5
Cyanidin-3-glucoside upregulated NDRG2 through the PI3K/AKT pathway to alleviate EMT and ECM in renal fibrosis.
Lu Q, Liu J, Xiong Y, Jian J, Wang J, Chen Z, Wan S, Liu X, Wang L
Scientific reports 2025 Mar 28;15(1):10695
Scientific reports 2025 Mar 28;15(1):10695
Genetic and Molecular Characterization of H9c2 Rat Myoblast Cell Line.
Liehr T, Kankel S, Hardt KS, Buhl EM, Noels H, Keller DT, Schröder-Lange SK, Weiskirchen R
Cells 2025 Mar 28;14(7)
Cells 2025 Mar 28;14(7)
Abnormal collagen deposition mediated by cartilage oligomeric matrix protein in the pathogenesis of oral submucous fibrosis.
Xiong Y, Li X, Sun B, Zhang J, Wu X, Guo F
International journal of oral science 2025 Mar 27;17(1):25
International journal of oral science 2025 Mar 27;17(1):25
Extracellular Matrix Reorganization During Endometrial Decidualization.
Gebril M, Mulder S, Das R, Nallasamy S
bioRxiv : the preprint server for biology 2025 Mar 25;
bioRxiv : the preprint server for biology 2025 Mar 25;
CDX1 improves nicotine induced cardiac fibroblasts activation and cardiomyocyte hypertrophy by alleviating autophagic flux impairment through modulation of LAPTM4B.
Li YY, Meng FL, Zhou SY, Du JM, Li WJ, Liu QY, Wu L, Zhao MM, Jin Y, Zhang QY, Li Y, Su GH
Scientific reports 2025 Mar 22;15(1):9985
Scientific reports 2025 Mar 22;15(1):9985
PPDPF preserves integrity of proximal tubule by modulating NMNAT activity in chronic kidney diseases.
Fang X, Zhong Y, Zheng R, Wu Q, Liu Y, Zhang D, Wang Y, Ding W, Wang K, Zhong F, Lin K, Yao X, Hu Q, Li X, Xu G, Liu N, Nie J, Li D, Geng H, Guan Y
Science advances 2025 Mar 21;11(12):eadr8648
Science advances 2025 Mar 21;11(12):eadr8648
Low intensity pulsed ultrasound alleviates synovial fibrosis in osteoarthritis via the PI3K/AKT pathway.
Liao Q, Chen J, Liu G
Scientific reports 2025 Mar 20;15(1):9644
Scientific reports 2025 Mar 20;15(1):9644
Discovery and Functional Characterization of a Recombinant Fragment of Human Collagen Type XVII.
Piao L, Li J, Li X, Su Y, Yuan X, Chang S, Cheng X, Fu S, Kong R
Journal of agricultural and food chemistry 2025 Mar 19;73(11):6724-6735
Journal of agricultural and food chemistry 2025 Mar 19;73(11):6724-6735
Ciliary neurotrophic factor (CNTF) contributes to pelvic organ prolapse by modulating collagen expression via the JAK2-STAT3 pathway.
Xu Z, Zhu Q, Yang Y, Shan W, Jiang F, Zou Q, Wang W
Journal of molecular histology 2025 Mar 14;56(2):107
Journal of molecular histology 2025 Mar 14;56(2):107
Trbp inhibits cardiac fibrosis through TGF-β pathway-mediated cross-talk between cardiomyocytes and fibroblasts.
Pan B, Hu D, Lu YW, Luo J, Xu XH, Guo H, Deng R, Liang Z, Wang Y, Ma Q, Mably JD, Tian J, Wang DZ
Clinical science (London, England : 1979) 2025 Mar 11;139(5):1-14
Clinical science (London, England : 1979) 2025 Mar 11;139(5):1-14
Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis.
Chang J, Lu J, Liu Q, Xiang T, Zhang S, Yi Y, Li D, Liu T, Liu Z, Chen X, Dong Z, Li C, Yi H, Yu S, Huang L, Qu F, Wang M, Wang D, Dong H, Cheng G, Zhu L, Li J, Li C, Wu P, Xie X, Teschendorff AE, Lin D, Wang X, Wu C
Cancer cell 2025 Mar 10;43(3):380-397.e7
Cancer cell 2025 Mar 10;43(3):380-397.e7
KLC3 activates PI3K/AKT signaling and promotes ovarian cancer cell proliferation and migration through COL3A1.
Yang J, He R, Zhang X, Wang X, Liu M, Liu X, Li Y
Oncology reports 2025 Jun;53(6)
Oncology reports 2025 Jun;53(6)
Multi-stage cooperative ROS-responsive hydrogel platform for drug delivery in myocardial ischemia-reperfusion injury repair.
Luo Q, Cheng N, Yang Y, Shao N, Nie T, Chen J, Huang C, Zhang S, Huang Y, Ieong CM, Zhang X, Hu K, Xiao Z, Luo L
Materials today. Bio 2025 Jun;32:101854
Materials today. Bio 2025 Jun;32:101854
Multifunctional chitosan-gelatin hydrogel inspired by traditional Chinese medicine for promoting malignant wound healing.
Zhao X, Zhang G, Zhang S, Liu R, Zhang M, Wang B, Zhang Y, Liu J, Wang H
International journal of biological macromolecules 2025 Jun;316(Pt 1):144461
International journal of biological macromolecules 2025 Jun;316(Pt 1):144461
Ultrasound-responsive taurine lipid nanoparticles attenuate oxidative stress and promote macrophage polarization for diabetic wound healing.
Luo Z, Zheng S, Hu Z, Li P, Zeng J, Lu Y, Ali M, Chen Z, Wang Q, Qi F
Free radical biology & medicine 2025 Jun;233:302-316
Free radical biology & medicine 2025 Jun;233:302-316
Mai-wei-yang-fei decoction protects against pulmonary fibrosis by reducing telomere shortening and inhibiting AECII senescence via FBW7/TPP1 regulation.
Wang J, Zhao Y, Wei Y, Li T, Huang T, Pan T, Wu J, Bai L, Zhu D, Zhao Q, Wang Z, Feng F, Zhou X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156682
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156682
Network pharmacology and experimental validation reveals the potential therapeutic effects of Polygonum cuspidatum against odontogenic keratocyst.
Yi JR, Zeng B, Liu JF, Man QW
Journal of stomatology, oral and maxillofacial surgery 2025 Jun;126(3):102105
Journal of stomatology, oral and maxillofacial surgery 2025 Jun;126(3):102105
Aerobic Exercise Upregulates Renal-Derived ELABELA to Improve Myocardial Fibrosis by Activating APJ-AMPK-Sirt1 and Inhibiting TGFβ1-Smad2/3 Signaling Pathways in Myocardial Infarction Mice.
Ren W, Xi Y, Ma Y, Duan X, Wang T, Yu M, Qin S, Gong DW, Tian Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70734
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70734
TIMP1 regulation of cardiac fibroblast proliferation via the TGF-β/Smad pathway in an in vitro model of atrial fibrillation.
Zhou Y, Zhang L, Zhang W, Gong Q, Zhang Z, Xu N, Wilson-Smith AR, Chen N
Journal of thoracic disease 2025 Jun 30;17(6):4249-4263
Journal of thoracic disease 2025 Jun 30;17(6):4249-4263
Heshuxiaoji pill suppresses steatohepatitis and fibrosis by regulating the AngII-BACH1 mediated vasoconstriction.
Pu Y, Ren W, Gan Z, Wang S, Peng M, Yue R, Huang R
Journal of ethnopharmacology 2025 Jun 26;350:119989
Journal of ethnopharmacology 2025 Jun 26;350:119989
Network pharmacology and bioinformatics analysis reveals: NXC improves cardiac lymphangiogenesis through miR-126-3p/SPRED1 regulating the VEGF-C axis to ameliorate post-myocardial infarction heart failure.
Xu J, Wang C, Xu Y, Wang H, Wang X
Journal of ethnopharmacology 2025 Jun 26;350:119959
Journal of ethnopharmacology 2025 Jun 26;350:119959
PRDM16 acts as a homeostasis regulation factor to suppress the transition of AKI to CKD via upregulation of eukaryotic initiation factor 6.
Li X, Xia Y, Li X, Guo Y, Qiu S, Li H, Li Y, Wu L, Zhang D
Cellular and molecular life sciences : CMLS 2025 Jun 23;82(1):252
Cellular and molecular life sciences : CMLS 2025 Jun 23;82(1):252
Nobiletin from Citrus reticulata Blanco alleviates pulmonary fibrosis through inhibiting the PI3K/AKT pathway and epithelial-mesenchymal transition.
Yu S, Liu K, Zhou F, Yang X, Zhang J, Yu K, Zhu Y, Qin L, Peng T, Zhang C, He Y
Journal of ethnopharmacology 2025 Jun 12;349:119965
Journal of ethnopharmacology 2025 Jun 12;349:119965
Biochanin a Alleviated Doxorubicin-Induced Cardiotoxicity but Did not Interfere With the Antitumor Effect of Doxorubicin.
Yang Y, Feng Z, Zhou F, Sun X, Shang J, Zhang N, Xia Y, Xie Y
Phytotherapy research : PTR 2025 Jul;39(7):3241-3253
Phytotherapy research : PTR 2025 Jul;39(7):3241-3253
FABP4 Inhibitor Improves Right Ventricular Fibrosis in Metabolic Syndrome- Related Pulmonary Hypertension due to Left Heart Disease in Mice.
Qiu H, Chen W, Chen J, Jun L, Chen Y, Tan Y, Wang T, Li J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70833
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70833
Hypoxia Induces HIF-1α Activation in Tendon Stem Cells to Enhance Extracellular Vesicle-Mediated Tendon Repair.
Wu Y, Zhang T, Miao Y, Zhang A, Wang S, Li X, Liu H, Guo Y, Sun Q, Li Z
ACS applied materials & interfaces 2025 Jul 30;17(30):42637-42657
ACS applied materials & interfaces 2025 Jul 30;17(30):42637-42657
Identifying fibroblast-derived sFRP2 as a therapeutic target and engineering siRNA therapy for uterine scarring.
Cheng J, Zhang S, Gui Q, Pu Z, Chen Z, Wei Q, Qi H, Zhang J
Nature communications 2025 Jul 25;16(1):6850
Nature communications 2025 Jul 25;16(1):6850
Gluconic acid alleviates hypertrophic scar formation through binding PLOD1, reducing p-AKT signaling and activating autophagy.
Li J, Zeng S, Sun Y, Zou J, Zhang E, Yan Q, Chen L, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156825
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156825
Enhanced THBS2 promotes collagen synthesis and inflammatory secretome of fibroblasts in idiopathic pulmonary fibrosis.
Yu L, Wang R, Hou Q, Yang F, Liu Y, Peng M, Dong Y, Liu Y, Cheng Z
Scientific reports 2025 Jul 17;15(1):25926
Scientific reports 2025 Jul 17;15(1):25926
Human adipose-derived mesenchymal stem cell-derived exosomes induce epithelial remodeling and anti-scar healing revealed by single-cell RNA sequencing.
Fu Y, Xie JL, Zhang XL, Xie GM, Zhang XM, Han YT, Xu MM, Zhang J, Zhang J
Journal of nanobiotechnology 2025 Jul 14;23(1):506
Journal of nanobiotechnology 2025 Jul 14;23(1):506
Alleviation of fibrosis and oxidative stress in pressure overload-induced cardiac remodeling and heart failure via SIRT3 activation by colchicine.
Wu M, Chen G, Peng Y, Luo S
Biochemical and biophysical research communications 2025 Jul 12;770:151957
Biochemical and biophysical research communications 2025 Jul 12;770:151957
Epac1 Inhibits Orbital Fibroblast Activation to Ameliorate Thyroid-Associated Orbitopathy-Like Features Through the JAK/STAT Signaling Pathway.
Liu R, Xin X, Ma S, Guo J, Wu C, Qi X, Luo B
Investigative ophthalmology & visual science 2025 Jul 1;66(9):68
Investigative ophthalmology & visual science 2025 Jul 1;66(9):68
Identification and localization of adhesion G protein-coupled receptor expression in the murine kidney.
Steichen H, Xue J, Zaidman NA
American journal of physiology. Renal physiology 2025 Jul 1;329(1):F11-F19
American journal of physiology. Renal physiology 2025 Jul 1;329(1):F11-F19
IGF-1 regulates LARP6-mediated collagen metabolism in vaginal fibroblasts of POP patients via the PI3K/AKT pathway.
Kong L, Wei L, Wang L, Geng M, Wang W, Liu X
Scientific reports 2025 Jul 1;15(1):21977
Scientific reports 2025 Jul 1;15(1):21977
ACE2 Inhibits Dermal Regeneration Through Ang II in Tissue Expansion.
Bai R, Liang B, Guo Y, Liu W, Wen Z, Wang Z, Zhang Y, Du J, Song Y, Yu Z, Ma X
Journal of cosmetic dermatology 2025 Jan;24(1):e16767
Journal of cosmetic dermatology 2025 Jan;24(1):e16767
Baricitinib represses the myocardial fibrosis via blocking JAK/STAT and TGF-β1 pathways in vivo and in vitro.
Feng R, Liu H, Chen Y
BMC cardiovascular disorders 2025 Jan 31;25(1):65
BMC cardiovascular disorders 2025 Jan 31;25(1):65
Efficacy and mechanism of Schisandra chinensis active component Gomisin A on diabetic skin wound healing: network pharmacology and in vivo experimental validation.
Zhang Z, Yang W, Chen J, Chen X, Gu Y
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118828
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118828
Comparison of chemical composition between imitation wild and transplanted Astragali Radix and their therapeutic effects on heart failure.
Zhang C, Zhu Y, Wang M, Chen R, Sun X
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118827
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118827
UHRF1 promotes epithelial-mesenchymal transition mediating renal fibrosis by activating the TGF-β/SMAD signaling pathway.
Yang L, Si P, Kuerban T, Guo L, Zhan S, Zuhaer Y, Zuo Y, Lu P, Bai X, Liu T
Scientific reports 2025 Jan 27;15(1):3346
Scientific reports 2025 Jan 27;15(1):3346
Highly effective treatment of bacterial infection-accompanied wounds by fat extract-embedded phototherapeutic hydrogel.
Wang H, Xiao Y, Zhuge D, Shi G, Liu C, Liang H, Wu J, Huang Y, Xie Y, Hu C, Xie J, Wang X, Yao Y, Wang F, Zhang X, Huang C, Zhao Y, Meng W, Chen Y, Chen M
Journal of nanobiotechnology 2025 Jan 23;23(1):39
Journal of nanobiotechnology 2025 Jan 23;23(1):39
Gualou Xiebai Banxia Decoction suppresses cardiomyocyte apoptosis in mice after myocardial infarction through activation of acetaldehyde dehydrogenase 2.
Deng B, Zhang G, Zeng Y, Li N, Hu C, Pang M, Lu S, Gu Y, Chen G, Zhou Y, Liu Y, Hua Y
Journal of ethnopharmacology 2025 Jan 13;339:119143
Journal of ethnopharmacology 2025 Jan 13;339:119143
PTB Regulates Keloid Fibroblast Migration and Proliferation Through Autophagy.
Huang R, Han B, Peng J, Jiao H
Aesthetic plastic surgery 2025 Feb;49(3):897-907
Aesthetic plastic surgery 2025 Feb;49(3):897-907
Nicotinamide N-methyltransferase negatively regulates metastasis-promoting property of cancer-associated fibroblasts in lung adenocarcinoma.
Wang P, Wang G, Li H, Yuan Y, Chen H, Wang S, Sun Z, Meng F, Li Y, Yang F, Wang J, Chen K, Qiu M
Cancer communications (London, England) 2025 Feb;45(2):110-137
Cancer communications (London, England) 2025 Feb;45(2):110-137
Nicotinamide n-methyltransferase inhibitor synergizes with sodium-glucose cotransporter 2 inhibitor to protect renal tubular epithelium in experimental models of type 2 diabetes mellitus.
Yang Y, Li F, Li Y, Li X, Zhao Z, Zhang N, Li H
Journal of diabetes and its complications 2025 Feb;39(2):108952
Journal of diabetes and its complications 2025 Feb;39(2):108952
α-arbutin prevents UVA-induced skin photodamage via alleviating DNA damage and collagen degradation in NIH-3T3 cells.
Zhao N, Nie X, Yan Y, Liu Z, Chen X, Shu P, Zhong J
Journal of photochemistry and photobiology. B, Biology 2025 Feb;263:113100
Journal of photochemistry and photobiology. B, Biology 2025 Feb;263:113100
Engineering Macrophage-Derived Exosome to Deliver Pirfenidone: A Novel Approach to Combat Silicotic Pulmonary Fibrosis.
Chen Z, Yun X, Tian J, Li F, Zhang Z, Meng J, Li N, Bian H, Duan S, Zhang L
Advanced healthcare materials 2025 Feb;14(4):e2403227
Advanced healthcare materials 2025 Feb;14(4):e2403227
Asiatic acid improves the damage of HaCaT cells induced by nitrogen mustard through inhibiting endoplasmic reticulum stress.
Liu H, Cheng J, Ye F, Dong X, Ge W, Wang X, Zhao Y, Dan G, Chen M, Sai Y
Toxicology research 2025 Feb;14(1):tfaf019
Toxicology research 2025 Feb;14(1):tfaf019
Danggui niantong decoction attenuates synovial fibrosis through regulating PI3k/AKT signaling pathway.
Liao Q, Wu S, Li X, Yuan LX
Journal of ethnopharmacology 2025 Feb 27;342:119381
Journal of ethnopharmacology 2025 Feb 27;342:119381
Keratinocyte-driven dermal collagen formation in the axolotl skin.
Ohashi A, Sakamoto H, Kuroda J, Kondo Y, Kamei Y, Nonaka S, Furukawa S, Yamamoto S, Satoh A
Nature communications 2025 Feb 24;16(1):1757
Nature communications 2025 Feb 24;16(1):1757
Growth Differentiation Factor 15 Inhibits Cardiac Fibrosis, Oxidative Stress, Inflammation, and Apoptosis in a Rat Model of Heart Failure with Preserved Ejection Fraction.
Meng X, Li Y, Meng L, Yang C, Xia C, Wang X, Wang F
Frontiers in bioscience (Landmark edition) 2025 Feb 18;30(2):26857
Frontiers in bioscience (Landmark edition) 2025 Feb 18;30(2):26857
IFN-γ-mediated inhibition of JAK/STAT signaling via nano-scutellarin treatment is an efficient strategy for ameliorating liver fibrosis.
Wang T, Liu B, Huang J, Zhao Q, Shen H, Bi T, Liu Z, Dai Y, Sun Q
Journal of translational medicine 2025 Feb 17;23(1):195
Journal of translational medicine 2025 Feb 17;23(1):195
Early assessment and treatment of ventricular remodeling in vivo via a targeted ultrasonic molecular probe loaded with oxygen and cholecystokinin.
Wang C, Cheng H, Dong X, Zhan Y, Liu Y, Wu N, Tang R, He H, Cao Y, Yang L, Ren J, Li X, Li P
Journal of nanobiotechnology 2025 Feb 12;23(1):104
Journal of nanobiotechnology 2025 Feb 12;23(1):104
Aqueous extract of Cornus officinalis alleviate NAFLD via protecting hepatocytes proliferation through regulation of the tricarboxylic acid cycle.
Liu B, Shao T, Xiao D, Yang S, Lin W, Sun L, Zhang W, Luo M, Zhao J, Yang L, Bai S, Deng D, Wang C, Wang S, Zhang R, Liu Z, An L
Journal of ethnopharmacology 2025 Feb 11;341:119330
Journal of ethnopharmacology 2025 Feb 11;341:119330
Intelligent sequential degradation hydrogels by releasing bimetal-phenolic for enhanced diabetic wound healing.
Zhang Y, Tang Z, Chen L, Yang M, Zeng Y, Bai X, Zhang B, Zhou J, Zhang W, Tang S
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:961-981
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:961-981
Uncovering the mechanistic basis of Rheum palmatum L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular docking, and experimental validation.
He W, Wei Z, Li S, Han S, Ma J, Wu L, Lu D, Ta G
Pharmaceutical biology 2025 Dec;63(1):582-606
Pharmaceutical biology 2025 Dec;63(1):582-606
Concentrated Micronized Fat Ameliorates Skin Fibrosis in Bleomycin-Induced Murine Model and Enhances Fat Graft Survival.
Ma X, Dong M, Yin N, Li F
Aesthetic plastic surgery 2025 Dec;49(24):6942-6953
Aesthetic plastic surgery 2025 Dec;49(24):6942-6953
Astragaloside IV protects against high altitude hypoxia-induced cardiac injury through the CaSR-NF-kB and EGFR-PI3K-AKT-MDM2 pathways.
Li X, Cao R, Zhang L, Chen J, Qin Z, Huang D, Nie Y, Duan Z, Pu L, Wang Z, Li R, Wang X, Liu W, Chen Z
Apoptosis : an international journal on programmed cell death 2025 Dec;30(11-12):3169-3189
Apoptosis : an international journal on programmed cell death 2025 Dec;30(11-12):3169-3189
Hypericin-mediated photodynamic therapy promotes apoptosis and inhibits fibrosis by inducing HMOX1-mediated ferroptosis in hypertrophic scar fibroblasts.
Li X, Chen Z, Liu M, An J, Shang J, Zhu G, Wen H, Guo G
Journal of photochemistry and photobiology. B, Biology 2025 Dec;273:113303
Journal of photochemistry and photobiology. B, Biology 2025 Dec;273:113303
Different Intensities of Exercise Affect the Prognosis of Ventricular Aneurysm in Mice by Regulating the Progression of Cardiac Fibrosis.
Qi RQ, Song J, Ma HB, Nie ML, Su LH, Dai CL, Zhou FG, Li SJ
Cardiovascular toxicology 2025 Dec;25(12):1891-1902
Cardiovascular toxicology 2025 Dec;25(12):1891-1902
Shenfu injection inhibits myocardial fibrosis by regulating glycolysis through the PI3K-AKT/HIF-1α signaling pathway.
Li X, Li D, Liu S, Wang Y, Fan X, Yan Z, Tan S, Zhuang P, Zhang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157529
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157529
Incorporating Stem Cell-Derived Small Extracellular Vesicles into a Multifunctional OHAMA-EPL Hydrogel Spray for Rapid Healing of Infected Skin Wounds.
He M, Wei Y, Chen X, Li J, Kang J, Li B, Liu D, Cai H
Advanced healthcare materials 2025 Dec;14(32):e04147
Advanced healthcare materials 2025 Dec;14(32):e04147
Loss of MFAP5 and Its Effect on Skin Homeostasis and Wound Healing.
Han C, Yuan H, Koh TJ, Chen L, Mecham RP, DiPietro LA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 15;39(23):e71273
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 15;39(23):e71273
Kirenol attenuates pressure overload-induced heart failure by enhancing autophagy in macrophages.
Huang Z, Pan L, Xiao Z, Rao F, Yakupu W, Rouzi A, Cheng K, Pang Y, Su Y, Wu D
International journal of cardiology 2025 Dec 1;440:133681
International journal of cardiology 2025 Dec 1;440:133681
Loss of Trim31 Worsens Cardiac Remodeling in a Mouse Model of Heart Failure by Enhancing the Activation of the NLRP3 Inflammasome.
Duan F, Li H, Lu B, Wang X, Xu X
Inflammation 2025 Aug;48(4):2650-2662
Inflammation 2025 Aug;48(4):2650-2662
Dissolvable microneedle-assisted transdermal administration of diacerein nanoparticles achieved satisfactory therapeutic effects in tendon-bone insertion repair by reducing oxidative stress and inflammation.
Sun J, Chen QZ, Hong AZ, Ju F, Wang HL, Zhang B, Liu W, Sun YC, Tan J, Yang QQ, Zhou YL
Materials today. Bio 2025 Aug;33:101999
Materials today. Bio 2025 Aug;33:101999
Platelet-rich plasma-derived exosomes have the novel ability to alleviate insertional Achilles tendinopathy by promoting tenogenesis in tendon stem/progenitor cells.
Zhang AY, Xie QZ, Guo SZ, Liu X, Yu YH, Tang H, Yao H, Guo L, Xu SB, Bian XT, Tao X
Biomaterials advances 2025 Aug;173:214272
Biomaterials advances 2025 Aug;173:214272
Mesenchymal Stem Cell-Derived Extracellular Vesicles Embedded in a Self-Adaptive Multifunctional Hydrogel for Rapid Healing of Infected Wounds.
Chen X, Wang X, He M, Kang J, Gu J, Wei Y, Li J, Li B, Hong X, Mao X, Liu D, Cai H
Advanced healthcare materials 2025 Aug;14(20):e2500980
Advanced healthcare materials 2025 Aug;14(20):e2500980
Butyrate protects against myocardial ischemia injury and cardiomyocyte pyroptosis by inhibiting MALT1-mediated Nrf2 ubiquitination and degradation.
Zhang P, Su Y, Cheng Y
Journal of molecular histology 2025 Aug 8;56(4):261
Journal of molecular histology 2025 Aug 8;56(4):261
SRPK1 is a significant factor in driving the progression of diabetic kidney fibrosis.
Han S, Ma S, Liu K, Qi R, Wang G, Qin W, Zhang X
Diabetology & metabolic syndrome 2025 Aug 6;17(1):316
Diabetology & metabolic syndrome 2025 Aug 6;17(1):316
Paclitaxel-mediated microtubule stabilization regulates flexor tendon repair in rats.
Yang JJ, Xu SW, Zhang XY, Mao WF, Wu YF
Bone & joint research 2025 Aug 6;14(8):685-695
Bone & joint research 2025 Aug 6;14(8):685-695
Nanofat promotes wound healing in skin following exposure to ionizing radiation.
Limido E, Weinzierl A, Ampofo E, Rübe CE, Tewary G, Harder Y, Menger MD, Laschke MW
Scientific reports 2025 Aug 29;15(1):31918
Scientific reports 2025 Aug 29;15(1):31918
Extracellular matrix reorganization during endometrial decidualization.
Gebril M, Mulder S, Das R, Nallasamy S
Histochemistry and cell biology 2025 Aug 28;163(1):84
Histochemistry and cell biology 2025 Aug 28;163(1):84
MSC-derived exosomes improve endometrial fibrosis via the lncRNA IGF2R/ miR-143-5p/AQP8 axis.
Huo X, Chen J, Qian M, Xue Q, Xu P, Wang Y, Jiang Z, Luo Q, Xiong Y
Stem cell research & therapy 2025 Aug 27;16(1):464
Stem cell research & therapy 2025 Aug 27;16(1):464
[Haematococcus pluvialis alleviates bleomycin-induced pulmonary fibrosis in mice by inhibiting transformation of lung fibroblasts into myofibroblast].
Zhang X, Man J, Zhang Y, Zheng Y, Wang H, Yuan Y, Xie X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Aug 20;45(8):1672-1681
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Aug 20;45(8):1672-1681
Nanoparticles reveal permanent and reversible changes to lymph node biomechanics during inflammatory response.
Ramirez A, Sriram V, Abbouchi Y, Patolia R, Passaro E, Kaluzienski M, Maisel K
bioRxiv : the preprint server for biology 2025 Aug 14;
bioRxiv : the preprint server for biology 2025 Aug 14;
Tanshinone IIA alleviates pulmonary fibrosis by modulating glutamine metabolic reprogramming based on [U-(13)C(5)]-glutamine metabolic flux analysis.
Shan B, Guo C, Zhou H, Chen J
Journal of advanced research 2025 Apr;70:531-544
Journal of advanced research 2025 Apr;70:531-544
Mesenteric adipose-derived exosomal TINAGL1 enhances intestinal fibrosis in Crohn's Disease via SMAD4.
Chen Y, Li J, Zhang X, Li S, Cheng Y, Fu X, Li J, Zhu L
Journal of advanced research 2025 Apr;70:139-158
Journal of advanced research 2025 Apr;70:139-158
Nrf2 deficiency aggravates hepatic cadmium accumulation, inflammatory response and subsequent injury induced by chronic cadmium exposure in mice.
Chen C, Han X, Xu N, Shen W, Wang G, Jiao J, Kong W, Yu J, Fu J, Pi J
Toxicology and applied pharmacology 2025 Apr;497:117263
Toxicology and applied pharmacology 2025 Apr;497:117263
BMAL1 Regulates Collagen Production in the Myometrium and Leiomyomas.
Dai Y, Ono M, Suzuki T, Hayashi S, Kojima J, Sasaki T, Fujiwara T, Daikoku T, Terakawa J, Maida Y, Ando H, Fujiwara H, Kuji N, Nishi H
Reproductive sciences (Thousand Oaks, Calif.) 2025 Apr;32(4):1115-1128
Reproductive sciences (Thousand Oaks, Calif.) 2025 Apr;32(4):1115-1128
ErTao decoction alleviates liver fibrosis by suppressing STING-mediated macrophages and NLRP3 inflammasome activation.
Jia H, Li J, Chen X, Liu Z, Wu C, Liu C, Zhang J, Luo M, Huang M, Huang S, Cai M, Gao L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156489
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156489
LIMA1 O-GlcNAcylation Promotes Hepatic Lipid Deposition through Inducing β-catenin-Regulated FASn Expression in Metabolic Dysfunction-Associated Steatotic Liver Disease.
Yang F, Chen Y, Zheng G, Gu K, Fan L, Li T, Zhu L, Yan Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2415941
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2415941
Fermented Cordyceps Powder alleviates silica-induced inflammation and fibrosis by inhibiting M1 macrophage polarization via the HMGB1-TLR4-NF-κB pathway.
Pu S, Meng X, Shi Y, Huang N, Zhang C, Pang A, Shao H, Jia Q
Journal of ethnopharmacology 2025 Apr 9;345:119631
Journal of ethnopharmacology 2025 Apr 9;345:119631
Chrysophanol Attenuates Cardiac Fibrosis and Arrhythmia by Suppressing the Endoplasmic Reticulum Stress/Pyroptosis Axis and Inflammation.
Liu C, Qiu S, Liu X, Huang R, Fang Z
Phytotherapy research : PTR 2025 Apr 5;
Phytotherapy research : PTR 2025 Apr 5;
Preventive Administration of Quercetin Promotes Survival and Reduces Adverse Ventricular Remodeling after myocardial infarction through facilitating M2-like macrophage polarization.
Wang L, Lin S, Wei Q, Li T, Mo Q, Bai R, Feng J, Zhan A, Yang X, Rong X, Guo J
International immunopharmacology 2025 Apr 4;151:114296
International immunopharmacology 2025 Apr 4;151:114296
A Novel Mechanism of the p53 Isoform Δ40p53α in Regulating Collagen III Expression in TGFβ1-Induced LX-2 Human Hepatic Stellate Cells.
Lee SY, Jang Y, Seok HY, Moon YH
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 30;39(8):e70541
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 30;39(8):e70541
CAFs activated by YAP1 upregulate cancer matrix stiffness to mediate hepatocellular carcinoma progression.
Yan W, Xiao GH, Wang LJ, Zhou Y, Yang F, Mou KH
Journal of translational medicine 2025 Apr 16;23(1):450
Journal of translational medicine 2025 Apr 16;23(1):450
Dehydrocorydaline attenuates bleomycin-induced pulmonary fibrosis by inhibiting fibroblast activation.
He J, Yue H, Zhang S, Dong R, Zhang F, Wang X, Wang K, Zhang H, Yang D, Dong Z, Liu H
Respiratory research 2025 Apr 12;26(1):136
Respiratory research 2025 Apr 12;26(1):136
The antifibrotic potential of transglutaminase 2 inhibition beyond TGFβ1 release in human kidney tissue and isolated cell cultures.
Prat-Duran J, Merrild C, Juste N, Pinilla E, Simonsen U, Nørregaard R, Buus NH
Life sciences 2025 Apr 1;366-367:123503
Life sciences 2025 Apr 1;366-367:123503
Lysozyme promotes renal fibrosis through the JAK/STAT3 signal pathway in diabetic nephropathy.
Ren Y, Yu M, Zheng D, He W, Jin J
Archives of medical science : AMS 2024;20(1):233-247
Archives of medical science : AMS 2024;20(1):233-247
Swimming alleviates myocardial fibrosis of type II diabetic rats through activating miR-34a-mediated SIRT1/PGC-1α/FNDC5 signal pathway.
Guo Y, Zhou F, Fan J, Wu T, Jia S, Li J, Chen N
PloS one 2024;19(9):e0310136
PloS one 2024;19(9):e0310136
Network pharmacology and experimental verification to decode the action of Qing Fei Hua Xian Decotion against pulmonary fibrosis.
Ke HL, Li RJ, Yu CC, Wang XP, Wu CY, Zhang YW
PloS one 2024;19(6):e0305903
PloS one 2024;19(6):e0305903
Melatonin serves as a novel treatment in bladder fibrosis through TGF-β1/Smad and EMT.
Zhang Y, Gong S, He W, Yuan J, Dong D, Zhang J, Wang H, Chen B
PloS one 2024;19(3):e0295104
PloS one 2024;19(3):e0295104
Antioxidant Carbon Dots and Ursolic Acid Co-Encapsulated Liposomes Composite Hydrogel for Alleviating Adhesion Formation and Enhancing Tendon Healing in Tendon Injury.
Peng C, Kang S, Jiang M, Yang M, Gong X
International journal of nanomedicine 2024;19:8709-8727
International journal of nanomedicine 2024;19:8709-8727
Liposomes Loaded with 5-Fluorouracil Can Improve the Efficacy in Pathological Scars.
Li Y, Sun Q, Hao L, Shan H, Jiang Z, Wang Y, Chen Z, Zhu W, Zhao S
International journal of nanomedicine 2024;19:7353-7365
International journal of nanomedicine 2024;19:7353-7365
Pretreatment of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes with Quercetin Enhances the Healing of Diabetic Skin Wounds by Modulating Host-Microbiota Interactions.
Wu S, Zhou Z, Li Y, Wu R, Jiang J
International journal of nanomedicine 2024;19:12557-12581
International journal of nanomedicine 2024;19:12557-12581
Qizhu Rougan Granules suppress liver fibrosis by inhibiting the expression of the P2Y14 receptor on hepatic stellate cells.
Tao Y, Niu Q, Yao Y, Wang K, Dong H, Zhao X, Zeng Z, Li H
Frontiers in pharmacology 2024;15:1528100
Frontiers in pharmacology 2024;15:1528100
Yishen paidu pills attenuates 5/6 nephrectomy induced kidney disease via inhibiting the PI3K/AKT/mTOR signaling pathway.
Liu S, Cao Y, Yuan Q, Xie Y, Zhu Y, Yao L, Zhang C
Frontiers in pharmacology 2024;15:1510098
Frontiers in pharmacology 2024;15:1510098
RMRP accelerates ligamentum flavum hypertrophy by regulating GSDMD-mediated pyroptosis through Gli1 SUMOylation.
Yan X, Liu T, Zhang R, Ma Q, Sun C
Frontiers in immunology 2024;15:1427970
Frontiers in immunology 2024;15:1427970
Abnormal mitochondrial iron metabolism damages alveolar type II epithelial cells involved in bleomycin-induced pulmonary fibrosis.
Shao M, Cheng H, Li X, Qiu Y, Zhang Y, Chang Y, Fu J, Shen M, Xu X, Feng D, Han Y, Yue S, Zhou Y, Luo Z
Theranostics 2024;14(7):2687-2705
Theranostics 2024;14(7):2687-2705
Branched-chain amino acids deficiency promotes diabetic cardiomyopathy by activating autophagy of cardiac fibroblasts.
Zhou ZY, Song K, Liu ZY, Ke YF, Shi Y, Cai K, Zhao R, Sun X, Tao H, Zhao JY
Theranostics 2024;14(19):7333-7348
Theranostics 2024;14(19):7333-7348
Activating autophagy promotes skin regeneration induced by mechanical stretch during tissue expansion.
Du J, Liu W, Song Y, Zhang Y, Dong C, Xiong S, Huang Z, Wang T, Ding J, He Q, Yu Z, Ma X
Burns & trauma 2024;12:tkad057
Burns & trauma 2024;12:tkad057
Comprehensive analysis of disulfidptosis-related genes and the immune microenvironment in heart failure.
Zhao L, Zhang J, Song Q, Dai C, Qin Y, Li A
Frontiers in cell and developmental biology 2024;12:1516898
Frontiers in cell and developmental biology 2024;12:1516898
Short-term cryoprotectant-free cryopreservation at -20°C does not affect the viability and regenerative capacity of nanofat.
Limido E, Weinzierl A, Ampofo E, Harder Y, Menger MD, Laschke MW
Frontiers in bioengineering and biotechnology 2024;12:1427232
Frontiers in bioengineering and biotechnology 2024;12:1427232
Adipose-derived stem cells derived decellularized extracellular matrix enabled skin regeneration and remodeling.
Zhang J, Xiang Y, Yang Q, Chen J, Liu L, Jin J, Zhu S
Frontiers in bioengineering and biotechnology 2024;12:1347995
Frontiers in bioengineering and biotechnology 2024;12:1347995
A novel senolytic drug for pulmonary fibrosis: BTSA1 targets apoptosis of senescent myofibroblasts by activating BAX.
Shen M, Fu J, Zhang Y, Chang Y, Li X, Cheng H, Qiu Y, Shao M, Han Y, Zhou Y, Luo Z
Aging cell 2024 Sep;23(9):e14229
Aging cell 2024 Sep;23(9):e14229
Sustained amphiregulin expression in intermediate alveolar stem cells drives progressive fibrosis.
Zhao R, Wang Z, Wang G, Geng J, Wu H, Liu X, Bin E, Sui J, Dai H, Tang N
Cell stem cell 2024 Sep 5;31(9):1344-1358.e6
Cell stem cell 2024 Sep 5;31(9):1344-1358.e6
Melatonin alleviates aging-related heart failure through melatonin receptor 1A/B knockout in mice.
Feng Z, Liu Y, Yang Y, Bai J, Lin QY, Xia YL, Xie Y
Heliyon 2024 Sep 30;10(18):e38098
Heliyon 2024 Sep 30;10(18):e38098
CD9 promotes TβR2-TβR1 association driving the transition of human dermal fibroblasts to myofibroblast under hypoxia.
Huang W, Zhang Z, Li X, Zheng Q, Wu C, Liu L, Chen Y, Zhang J, Jiang X
Molecular medicine (Cambridge, Mass.) 2024 Sep 27;30(1):162
Molecular medicine (Cambridge, Mass.) 2024 Sep 27;30(1):162
NBQX mediates ventricular fibrillation susceptibility in rat models of anxiety via the Nrf2/HO-1 pathway.
Hu Y, Qu C, Zou Y, Liu X, Zhang C, Yang B
Heliyon 2024 Sep 15;10(17):e37358
Heliyon 2024 Sep 15;10(17):e37358
Intermedin Alleviates Diabetic Cardiomyopathy by Up-Regulating CPT-1β through Activation of the Phosphatidyl Inositol 3 Kinase/Protein Kinase B Signaling Pathway.
Zhao J, Han L, Zhang YR, Liu SM, Ji DR, Wang R, Yu YR, Jia MZ, Chai SB, Tang HF, Huang W, Qi YF
Pharmaceuticals (Basel, Switzerland) 2024 Sep 12;17(9)
Pharmaceuticals (Basel, Switzerland) 2024 Sep 12;17(9)
Krüppel-like transcription factor 14 alleviates alveolar epithelial cell senescence by inhibiting endoplasmic reticulum stress in pulmonaryfibrosis.
Zhong WJ, Zhang CY, Duan JX, Chen MR, Ping-Deng, Zhang BL, Yang NS, Sha HX, Zhang J, Xiong JB, Guan CX, Zhou Y
International journal of biological macromolecules 2024 Sep 11;280(Pt 1):135351
International journal of biological macromolecules 2024 Sep 11;280(Pt 1):135351
Roles of m(6)A modification in regulating PPER pathway in cadmium-induced pancreatic β cell death.
Sun Y, Li R, Li W, Zhang N, Liu G, Zhao B, Mei Z, Gu S, He Z
Ecotoxicology and environmental safety 2024 Sep 1;282:116672
Ecotoxicology and environmental safety 2024 Sep 1;282:116672
Insulin-transferrin-selenium promote formation of tissue-engineered vascular grafts in early stage of culture.
Sun X, Wang N, Jiang H, Liu Q, Xiao C, Xu J, Wu Y, Mei J, Wu S, Lin Z
Preparative biochemistry & biotechnology 2024 Oct;54(9):1186-1195
Preparative biochemistry & biotechnology 2024 Oct;54(9):1186-1195
Attenuation of renal fibrosis in mice due to lack of bombesin receptor-activated protein homologue.
Peng Z, Wang H, Zheng J, Chen H, Wang J, Weber HC, Yuan L, Qin X, Xiang Y, Liu C, Ji M, Liu H, Qu X
Clinical and experimental pharmacology & physiology 2024 Oct;51(10):e13916
Clinical and experimental pharmacology & physiology 2024 Oct;51(10):e13916
CircNSD1 promotes cardiac fibrosis through targeting the miR-429-3p/SULF1/Wnt/β-catenin signaling pathway.
Ji DN, Jin SD, Jiang Y, Xu FY, Fan SW, Zhao YL, Liu XQ, Sun H, Cheng WZ, Zhang XY, Guan XX, Zhang BW, Du ZM, Wang Y, Wang N, Zhang R, Zhang MY, Xu CQ
Acta pharmacologica Sinica 2024 Oct;45(10):2092-2106
Acta pharmacologica Sinica 2024 Oct;45(10):2092-2106
Protective effect and mechanism of lycium barbarum polysaccharide against UVB-induced skin photoaging.
Fan L, Luan X, Jia Y, Ma L, Wang Z, Yang Y, Chen Q, Cui X, Luo D
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2024 Oct;23(10):1931-1943
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2024 Oct;23(10):1931-1943
Neutrophil-Mediated Nanozyme Delivery System for Acute Kidney Injury Therapy.
Yang Y, Du J, Gan J, Song X, Shu J, An C, Lu L, Wei H, Che J, Zhao X
Advanced healthcare materials 2024 Oct;13(26):e2401198
Advanced healthcare materials 2024 Oct;13(26):e2401198
S100A2 activation promotes interstitial fibrosis in kidneys by FoxO1-mediated epithelial-mesenchymal transition.
Yang X, Zheng F, Yan P, Liu X, Chen X, Du X, Zhang Y, Wang P, Chen C, Lu H, Bai Y
Cell biology and toxicology 2024 Oct 9;40(1):86
Cell biology and toxicology 2024 Oct 9;40(1):86
LMK235 ameliorates inflammation and fibrosis after myocardial infarction by inhibiting LSD1-related pathway.
Lv F, Xie L, Li L, Lin J
Scientific reports 2024 Oct 8;14(1):23450
Scientific reports 2024 Oct 8;14(1):23450
Carbon monoxide attenuates cellular senescence-mediated pulmonary fibrosis via modulating p53/PAI-1 pathway.
Wang Q, Li A, Li Q, Li J, Wang Q, Wu S, Meng J, Liu C, Wang D, Chen Y
European journal of pharmacology 2024 Oct 5;980:176843
European journal of pharmacology 2024 Oct 5;980:176843
Modification of transvaginal polypropylene mesh with co-axis electrospun nanofibrous membrane to alleviate complications following surgical implantation.
Guo T, Hu X, Du Z, Wang X, Lang J, Liu J, Xu H, Sun Z
Journal of nanobiotechnology 2024 Oct 3;22(1):598
Journal of nanobiotechnology 2024 Oct 3;22(1):598
Nanofat Improves Vascularization and Tissue Integration of Dermal Substitutes without Affecting Their Biocompatibility.
Bonomi F, Limido E, Weinzierl A, Ampofo E, Harder Y, Menger MD, Laschke MW
Journal of functional biomaterials 2024 Oct 3;15(10)
Journal of functional biomaterials 2024 Oct 3;15(10)
Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumor growth and metastasis.
Jones MG, Sun D, Min KHJ, Colgan WN, Tian L, Weir JA, Chen VZ, Koblan LW, Yost KE, Mathey-Andrews N, Russell AJC, Stickels RR, Balderrama KS, Rideout WM 3rd, Chang HY, Jacks T, Chen F, Weissman JS, Yosef N, Yang D
bioRxiv : the preprint server for biology 2024 Oct 24;
bioRxiv : the preprint server for biology 2024 Oct 24;
Selenium supplementation elevated SELENBP1 to inhibit fibroblast activation in pulmonary arterial hypertension.
Liang B, Lin W, Tang Y, Li T, Chen Q, Zhang W, Zhou X, Ma J, Liu B, Yu Z, Zha L, Zhang M
iScience 2024 Oct 18;27(10):111036
iScience 2024 Oct 18;27(10):111036
Identification of COL3A1 as a candidate protein involved in the crosstalk between obesity and diarrhea using quantitative proteomics and machine learning.
Wang Y, Wang X, Niu X, Han K, Ru N, Xiang J, Linghu E
European journal of pharmacology 2024 Oct 15;981:176881
European journal of pharmacology 2024 Oct 15;981:176881
Dapagliflozin alleviates right heart failure by promoting collagen degradation by reducing ROS levels.
Liu DD, Liu XL, Zheng TF, Li X, Zhao YC, Pan JC, Yuan C, Wang QQ, Zhang M
European journal of pharmacology 2024 Oct 15;981:176875
European journal of pharmacology 2024 Oct 15;981:176875
Irisin suppresses PDGF-BB-induced proliferation of vascular smooth muscle cells in vitro by activating AMPK/mTOR-mediated autophagy.
Qi F, Deng Y, Huang W, Cai Y, Hong K, Xiang S
European journal of histochemistry : EJH 2024 Oct 15;68(4)
European journal of histochemistry : EJH 2024 Oct 15;68(4)
NIR-II light based combinatorial management of hypertrophic scar by inducing autophagy in fibroblasts.
Dong Y, Wang H, Zhang Y, Wu Y, Lu L, Yu H, Zhou L, Zhao P, Ouyang S, Song Z, Hu Z, Lv D, Rong Y, Zhao Z, Tao J, Tang B, Luo S
Journal of nanobiotechnology 2024 Oct 15;22(1):625
Journal of nanobiotechnology 2024 Oct 15;22(1):625
The LncRNA6524/miR-92a-2-5p/Dvl1/Wnt/β-catenin axis promotes renal fibrosis in the UUO mouse model.
Xie Y, Zhang G, Pan J, Qiu S, Zhang D
Archives of biochemistry and biophysics 2024 Nov;761:110175
Archives of biochemistry and biophysics 2024 Nov;761:110175
NAT10-mediated RNA ac4C acetylation contributes to the myocardial infarction-induced cardiac fibrosis.
Li J, Yushanjiang F, Fang Z, Liu WL
Journal of cellular and molecular medicine 2024 Nov;28(21):e70141
Journal of cellular and molecular medicine 2024 Nov;28(21):e70141
Cardamonin intervenes in myocardial hypertrophy progression by regulating Usp18.
Feng Z, Pan L, Qiao C, Yang Y, Yang X, Xie Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155970
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155970
Mitophagy deficiency activates stimulator of interferon genes activation and aggravates pathogenetic cardiac remodeling.
Zhou G, Wang X, Guo M, Qu C, Gao L, Yu J, Li Y, Luo S, Shi Q, Guo Y
Genes & diseases 2024 Nov;11(6):101074
Genes & diseases 2024 Nov;11(6):101074
Gastrodin attenuates diabetic cardiomyopathy characterized by myocardial fibrosis by inhibiting the KLK8-PAR1 signaling axis.
Zhang M, Zhang Y, He J, Wang X, Wang Y, Li L, Tao L, Zhang M, Shen X
Chinese medicine 2024 Nov 22;19(1):164
Chinese medicine 2024 Nov 22;19(1):164
The in vivo effects of knockdown of long non-coding RNA XIST on fibroid growth and gene expression.
Chuang TD, Ton N, Rysling S, Khorram O
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70140
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70140
HIF-1α knockdown attenuates phenotypic transformation and oxidative stress induced by high salt in human aortic vascular smooth muscle cells.
Deng W, Huang S, Yu L, Gao B, Pan Y, Wang X, Li L
Scientific reports 2024 Nov 15;14(1):28100
Scientific reports 2024 Nov 15;14(1):28100
Astilbin improves the therapeutic effects of mesenchymal stem cells in AKI-CKD mice by regulating macrophage polarization through PTGS2-mediated pathway.
Geng X, Fu Z, Geng G, Chi K, Liu C, Hong H, Cai G, Chen X, Hong Q
Stem cell research & therapy 2024 Nov 14;15(1):427
Stem cell research & therapy 2024 Nov 14;15(1):427
Dynamic relationship among extracellular matrix and body wall cells in Hirudo verbana morphogenesis.
Pulze L, Baranzini N, Acquati F, Marcolli G, Grimaldi A
Cell and tissue research 2024 May;396(2):213-229
Cell and tissue research 2024 May;396(2):213-229
Inducible Fgf13 ablation alleviates cardiac fibrosis via regulation of microtubule stability.
Wang C, Wang X, Zhang Y, Mi Y, Han Y, Zhi Y, Zhao R, Cui N, Ma Q, Zhang H, Xue D, Qiao R, Han J, Yu Y, Li J, Shaiea M, Liu D, Gu G, Wang C
Acta biochimica et biophysica Sinica 2024 May 30;56(12):1802-1812
Acta biochimica et biophysica Sinica 2024 May 30;56(12):1802-1812
CXCL4:NLRP3-mediated pyroptosis product that regulates cardiac fibrosis.
Wei J, Peng MY, Wang SN, Lu HX
International immunopharmacology 2024 May 30;133:112096
International immunopharmacology 2024 May 30;133:112096
Association of attenuated leptin signaling pathways with impaired cardiac function under prolonged high-altitude hypoxia.
Wang J, Liu S, Sun L, Kong Z, Chai J, Wen J, Tian X, Chen N, Xu C
Scientific reports 2024 May 3;14(1):10206
Scientific reports 2024 May 3;14(1):10206
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity.
Wang L, Li C, Zhan H, Li S, Zeng K, Xu C, Zou Y, Xie Y, Zhan Z, Yin S, Zeng Y, Chen X, Lv G, Han Z, Zhou D, Zhou D, Yang Y, Zhou A
Cell reports. Medicine 2024 May 21;5(5):101533
Cell reports. Medicine 2024 May 21;5(5):101533
Neferine mitigates angiotensin II-induced atrial fibrillation and fibrosis via upregulation of Nrf2/HO-1 and inhibition of TGF-β/p-Smad2/3 pathways.
Jiang XX, Zhang R, Wang HS
Aging 2024 May 21;16(10):8630-8644
Aging 2024 May 21;16(10):8630-8644
Empagliflozin attenuates liver fibrosis in high-fat diet/streptozotocin-induced mice by modulating gut microbiota.
Huang C, Qian J, Liu Y, Zhang L, Yang Y
Clinical and experimental pharmacology & physiology 2024 Mar;51(3):e13842
Clinical and experimental pharmacology & physiology 2024 Mar;51(3):e13842
Therapeutic potential and mechanisms of Rifaximin in ameliorating iron overload-induced ferroptosis and liver fibrosis in vivo and in vitro.
Yuan Q, Fang Y, Guo J, Zhang Z, Liao J, Kuang J
Toxicology and applied pharmacology 2024 Mar;484:116845
Toxicology and applied pharmacology 2024 Mar;484:116845
Integrin β8 prevents pericyte-myofibroblast transition and renal fibrosis through inhibiting the TGF-β1/TGFBR1/Smad3 pathway in diabetic kidney disease.
Cao Y, Su H, Zeng J, Xie Y, Liu Z, Liu F, Qiu Y, Yi F, Lin J, Hammes HP, Zhang C
Translational research : the journal of laboratory and clinical medicine 2024 Mar;265:36-50
Translational research : the journal of laboratory and clinical medicine 2024 Mar;265:36-50
Bilirubin/morin self-assembled nanoparticle-engulfed collagen/polyvinyl alcohol hydrogel accelerates chronic diabetic wound healing by modulating inflammation and ameliorating oxidative stress.
Zhao YZ, Du CC, Xuan Y, Huang D, Qi B, Shi Y, Shen X, Zhang Y, Fu Y, Chen Y, Kou L, Yao Q
International journal of biological macromolecules 2024 Mar;261(Pt 1):129704
International journal of biological macromolecules 2024 Mar;261(Pt 1):129704
Machine learning and single-cell transcriptome profiling reveal regulation of fibroblast activation through THBS2/TGFβ1/P-Smad2/3 signalling pathway in hypertrophic scar.
Song B, Zhu Y, Zhao Y, Wang K, Peng Y, Chen L, Yu Z, Song B
International wound journal 2024 Mar;21(3):e14481
International wound journal 2024 Mar;21(3):e14481
Mac-1 deficiency ameliorates pressure overloaded heart failure through inhibiting macrophage polarization and activation.
Lin QY, Yu WJ, Bai J, Jiang WX, Li HH
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167048
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167048
Downregulation of the kidney glucagon receptor, essential for renal function and systemic homeostasis, contributes to chronic kidney disease.
Wang MY, Zhang Z, Zhao S, Onodera T, Sun XN, Zhu Q, Li C, Li N, Chen S, Paredes M, Gautron L, Charron MJ, Marciano DK, Gordillo R, Drucker DJ, Scherer PE
Cell metabolism 2024 Mar 5;36(3):575-597.e7
Cell metabolism 2024 Mar 5;36(3):575-597.e7
DNMT1 methylation of LncRNA-ANRIL causes myocardial fibrosis pyroptosis by interfering with the NLRP3/Caspase-1 pathway.
Liu Z, Gao L, Kan C, Chen X, Shi K, Wang W
Cellular and molecular biology (Noisy-le-Grand, France) 2024 Mar 31;70(3):197-203
Cellular and molecular biology (Noisy-le-Grand, France) 2024 Mar 31;70(3):197-203
Human amniotic MSCs-mediated anti-inflammation of CD206(hi)IL-10(hi) macrophages alleviates isoproterenol-induced ventricular remodeling in mice.
Huang QM, Long YL, Wang JN, Wu J, Tang WL, Wang XY, Zhang ZH, Zhuo YQ, Guan XH, Deng KY, Xin HB
International immunopharmacology 2024 Mar 10;129:111660
International immunopharmacology 2024 Mar 10;129:111660
Effects of gas signaling molecule SO(2) in cardiac functions of hyperthyroid rats.
Yang Q, Yang T, Liu X, Liu S, Liu W, Nie L, Chu C, Yang J
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2024 Mar 1;28(2):129-143
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2024 Mar 1;28(2):129-143
The total xanthones extracted from Gentianella acuta alleviates HFpEF by activating the IRE1α/Xbp1s pathway.
Zhao L, Qin Y, Liu Y, An L, Liu W, Zhang C, Song Q, Dai C, Zhang J, Li A
Journal of cellular and molecular medicine 2024 Jun;28(11):e18466
Journal of cellular and molecular medicine 2024 Jun;28(11):e18466
CILP2 promotes hypertrophic scar through Snail acetylation by interaction with ACLY.
Wang J, Du J, Wang Y, Song Y, Wu J, Wang T, Yu Z, Song B
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167202
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167202
Protective role of hydrogen sulfide against diabetic cardiomyopathy by inhibiting pyroptosis and myocardial fibrosis.
Liu M, Zeng C, Zhang Y, Xin Y, Deng S, Hu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116613
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116613
Activation of the Wnt/β-catenin signalling pathway enhances exosome production by hucMSCs and improves their capability to promote diabetic wound healing.
Wang L, Chen J, Song J, Xiang Y, Yang M, Xia L, Yang J, Hou X, Chen L, Wang L
Journal of nanobiotechnology 2024 Jun 26;22(1):373
Journal of nanobiotechnology 2024 Jun 26;22(1):373
Platelet membrane biomimetic nanoparticle-targeted delivery of TGF-β1 siRNA attenuates renal inflammation and fibrosis.
Fei S, Ma Y, Zhou B, Chen X, Zhang Y, Yue K, Li Q, Gui Y, Xiang T, Liu J, Yang B, Wang L, Huang X
International journal of pharmaceutics 2024 Jun 25;659:124261
International journal of pharmaceutics 2024 Jun 25;659:124261
In Vivo Effects of Bay 11-7082 on Fibroid Growth and Gene Expression: A Preclinical Study.
Chuang TD, Ton N, Rysling S, Khorram O
Cells 2024 Jun 24;13(13)
Cells 2024 Jun 24;13(13)
Single-cell transcriptomic-informed deconvolution of bulk data identifies immune checkpoint blockade resistance in urothelial cancer.
Wang L, Izadmehr S, Sfakianos JP, Tran M, Beaumont KG, Brody R, Cordon-Cardo C, Horowitz A, Sebra R, Oh WK, Bhardwaj N, Galsky MD, Zhu J
iScience 2024 Jun 21;27(6):109928
iScience 2024 Jun 21;27(6):109928
Targeting the long non-coding RNA MIAT for the treatment of fibroids in an animal model.
Chuang TD, Ton N, Manrique N, Rysling S, Khorram O
Clinical science (London, England : 1979) 2024 Jun 19;138(12):699-709
Clinical science (London, England : 1979) 2024 Jun 19;138(12):699-709
Potential Involvement of M1 Macrophage and VLA4/VCAM-1 Pathway in the Valvular Damage Due to Rheumatic Heart Disease.
Xian S, Li Y, Bai L, Tang S, Meng Z, Wen H, Huang F, Zeng Z
Frontiers in bioscience (Landmark edition) 2024 Jun 18;29(6):219
Frontiers in bioscience (Landmark edition) 2024 Jun 18;29(6):219
C-phycocyanin reinforces autophagy to block pulmonary fibrogenesis by inhibiting lncIAPF biogenesis.
Hu W, Wang Y, Yang H, Zhang L, Liu B, Ji Y, Song X, Lv C, Zhang S
Archives of pharmacal research 2024 Jul;47(7):659-674
Archives of pharmacal research 2024 Jul;47(7):659-674
Effects of Acupotomy on Immobilization-Induced Gastrocnemius Contracture and Fibrosis in Rats via Wnt/β-Catenin Signaling.
Hu R, Pan JK, Li JH, Zhang H, Li SR, Zhang Y
Chinese journal of integrative medicine 2024 Jul;30(7):633-642
Chinese journal of integrative medicine 2024 Jul;30(7):633-642
Resistance exercise upregulates Irisin expression and suppresses myocardial fibrosis following myocardial infarction via activating AMPK-Sirt1 and inactivating TGFβ1-Smad2/3.
Li H, Qin S, Tang J, Wang T, Ren W, Di L, Bo W, Ma Y, Wu F, Xu Z, Song W, Cai M, Xi Y, Tian Z
Acta physiologica (Oxford, England) 2024 Jul;240(7):e14163
Acta physiologica (Oxford, England) 2024 Jul;240(7):e14163
Microvascular Fragment-Loaded Platelet-Rich Plasma Dressing Promotes Cutaneous Wound Healing.
Dinter MC, Bickelmann C, Nickels RM, Menger MD, Laschke MW
Advances in wound care 2024 Jul;13(7):336-349
Advances in wound care 2024 Jul;13(7):336-349
LDHA contributes to nicotine induced cardiac fibrosis through autophagy flux impairment.
Wu HH, Du JM, Liu P, Meng FL, Li YY, Li WJ, Wang SX, Du NL, Zheng Y, Zhang L, Wang HY, Liu YR, Song CH, Ni X, Li Y, Su GH
International immunopharmacology 2024 Jul 30;136:112338
International immunopharmacology 2024 Jul 30;136:112338
DKK1 loss promotes endometrial fibrosis via autophagy and exosome-mediated macrophage-to-myofibroblast transition.
Zhang Z, Hu J
Journal of translational medicine 2024 Jul 3;22(1):617
Journal of translational medicine 2024 Jul 3;22(1):617
Zhen-wu-tang protects against myocardial fibrosis by inhibiting M1 macrophage polarization via the TLR4/NF-κB pathway.
Fang R, Zhou R, Ju D, Li M, Wang H, Pan L, Wang X, Han M, Yu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155719
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155719
The mechano-chemical circuit in fibroblasts and dendritic cells drives basal cell proliferation in psoriasis.
Jiang J, Shao X, Liu W, Wang M, Li Q, Wang M, Xiao Y, Li K, Liang H, Wang N, Xu X, Wu Y, Gao X, Xie Q, Xiang X, Liu W, Wu W, Yang L, Gu ZZ, Chen J, Lei M
Cell reports 2024 Jul 23;43(7):114513
Cell reports 2024 Jul 23;43(7):114513
Mesenchymal stem cells ameliorate inflammation and pyroptosis in diabetic cardiomyopathy via the miRNA-223-3p/NLRP3 pathway.
Yang Q, Chen Q, Li S, Luo J
Diabetology & metabolic syndrome 2024 Jul 2;16(1):146
Diabetology & metabolic syndrome 2024 Jul 2;16(1):146
CircSMAD3 represses SMAD3 phosphorylation and ameliorates cardiac remodeling by recruiting YBX1.
Mei S, Ma X, Zhou L, Wuyun Q, Wang J, Xiao Q, Wang M, Zhang K, Chen C, Yan J, Ding H
iScience 2024 Jul 19;27(7):110200
iScience 2024 Jul 19;27(7):110200
MBNL2 promotes aging-related cardiac fibrosis via inhibited SUMOylation of Krüppel-like factor4.
Lu J, Zhao Q, Wang L, Li J, Wang H, Lv L, Yuan M, Chen Q, Zhang Z, Luo D, Sheng S, Yuan K, Liu G, Liu M, Shi Y, Guo Y, Dong Z
iScience 2024 Jul 19;27(7):110163
iScience 2024 Jul 19;27(7):110163
Designer cellular spheroids with DNA origami for drug screening.
Wei J, Sun Y, Wang H, Zhu T, Li L, Zhou Y, Liu Q, Dai Z, Li W, Yang T, Wang B, Zhu C, Shen X, Yao Q, Song G, Zhao Y, Pei H
Science advances 2024 Jul 19;10(29):eado9880
Science advances 2024 Jul 19;10(29):eado9880
Procyanidin C1 inhibits bleomycin-induced pulmonary fibrosis in mice by selective clearance of senescent myofibroblasts.
Shao M, Qiu Y, Shen M, Liu W, Feng D, Luo Z, Zhou Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23749
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23749
Isorhamnetin inhibits hypertrophic scar formation through TGF-β1/Smad and TGF-β1/CREB3L1 signaling pathways.
Wu J, Song Y, Wang J, Wang T, Yang L, Shi Y, Song B, Yu Z
Heliyon 2024 Jul 15;10(13):e33802
Heliyon 2024 Jul 15;10(13):e33802
Caveolin-1 scaffolding domain-derived peptide enhances erectile function by regulating oxidative stress, mitochondrial dysfunction, and apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury.
Xi Y, Feng Z, Xia T, Hong Y, Wu J, Chen J, Ge Y, Xiao H
Life sciences 2024 Jul 1;348:122694
Life sciences 2024 Jul 1;348:122694
Multi-omics analyses reveal bacteria and catalase associated with keloid disease.
Shan M, Xiao M, Xu J, Sun W, Wang Z, Du W, Liu X, Nie M, Wang X, Liang Z, Liu H, Hao Y, Xia Y, Zhu L, Song K, Feng C, Meng T, Wang Z, Cao W, Wang L, Zheng Z, Wang Y, Huang Y
EBioMedicine 2024 Jan;99:104904
EBioMedicine 2024 Jan;99:104904
Endogenous hydrogen sulphide deficiency and exogenous hydrogen sulphide supplement regulate skin fibroblasts proliferation via necroptosis.
Li L, Chen X, Liu C, He Z, Shen Q, Zhu Y, Wang X, Cao S, Yang S
Experimental dermatology 2024 Jan;33(1):e14972
Experimental dermatology 2024 Jan;33(1):e14972
Metabolic reprogramming driven by EZH2 inhibition depends on cell-matrix interactions.
W-M Fan T, Islam JMM, Higashi RM, Lin P, Brainson CF, Lane AN
The Journal of biological chemistry 2024 Jan;300(1):105485
The Journal of biological chemistry 2024 Jan;300(1):105485
Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling.
Dong Y, Cao X, Huang J, Hu Z, Chen C, Chen M, Long Q, Xu Z, Lv D, Rong Y, Luo S, Wang H, Deng W, Tang B
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166887
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166887
Biochanin A inhibits cardiac hypertrophy and fibrosis in vivo and in vitro.
Feng Z, Zhang N, Bai J, Lin QY, Xie Y, Xia YL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116002
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116002
Zhilong Huoxue Tongyu capsule alleviates myocardial fibrosis by improving endothelial cell dysfunction.
Bi T, Zhou Y, Mao L, Liang P, Liu J, Yang L, Ren G, Mazhar M, Shen H, Liu P, Spáčil R, Guo Q, Luo G, Yang S, Ren W
Journal of traditional and complementary medicine 2024 Jan;14(1):40-54
Journal of traditional and complementary medicine 2024 Jan;14(1):40-54
Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid.
Wu K, Liu Y, Xia J, Liu J, Wang K, Liang H, Xu F, Liu D, Nie D, Tang X, Huang A, Chen C, Tang N
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(2):e2304408
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(2):e2304408
Intermittent mild cold stimulation alleviates cold stress-induced pulmonary fibrosis by inhibiting the TGF-β1/Smad signaling pathway in broilers.
Wei H, Zhang Y, Li T, Zhang S, Yin J, Liu Y, Xing L, Bao J, Li J
Poultry science 2024 Jan;103(1):103246
Poultry science 2024 Jan;103(1):103246
Metabolomics reveals that chronic restraint stress alleviates carbon tetrachloride-induced hepatic fibrosis through the INSR/PI3K/AKT/AMPK pathway.
Zhang S, Liu B, Huang L, Zhang R, An L, Liu Z
Journal of molecular medicine (Berlin, Germany) 2024 Jan;102(1):113-128
Journal of molecular medicine (Berlin, Germany) 2024 Jan;102(1):113-128
CTRP3 alleviates mitochondrial dysfunction and oxidative stress injury in pathological cardiac hypertrophy by activating UPRmt via the SIRT1/ATF5 axis.
Shi L, Tan Y, Zheng W, Cao G, Zhou H, Li P, Cui J, Song Y, Feng L, Li H, Shan W, Zhang B, Yi W
Cell death discovery 2024 Jan 26;10(1):53
Cell death discovery 2024 Jan 26;10(1):53
COL3A1 is a potential diagnostic biomarker for synovial chondromatosis and affects the cell cycle and migration of chondrocytes.
Chen WK, Zhang HJ, Liu J, Dai Z, Zhan XL
International immunopharmacology 2024 Jan 25;127:111416
International immunopharmacology 2024 Jan 25;127:111416
Self-assembled coating with a metal-polyphenolic network for intraocular lens modification to prevent posterior capsule opacification.
Wang Y, Wen C, Jing R, Yang Y, Qin Y, Qi T, Hu C, Bai X, Wu C, Pei C
Biomedical materials (Bristol, England) 2024 Jan 22;19(2)
Biomedical materials (Bristol, England) 2024 Jan 22;19(2)
Phomopsterone B Alleviates Liver Fibrosis through mTOR-Mediated Autophagy and Apoptosis Pathway.
Peng ML, Zhang LJ, Luo Y, Xu SY, Long XM, Ao JL, Liao SG, Zhu QF, He X, Xu GB
Molecules (Basel, Switzerland) 2024 Jan 15;29(2)
Molecules (Basel, Switzerland) 2024 Jan 15;29(2)
Tanshinone IIA ameliorates energy metabolism dysfunction of pulmonary fibrosis using (13)C metabolic flux analysis.
Shan B, Zhou H, Guo C, Liu X, Wu M, Zhai R, Chen J
Journal of pharmaceutical analysis 2024 Feb;14(2):244-258
Journal of pharmaceutical analysis 2024 Feb;14(2):244-258
The Upregulation of Leucine-Rich Repeat Containing 1 Expression Activates Hepatic Stellate Cells and Promotes Liver Fibrosis by Stabilizing Phosphorylated Smad2/3.
Wang Y, Li X, Guan X, Song Z, Liu H, Guan Z, Wang J, Zhu L, Zhang D, Zhao L, Xie P, Wei X, Shang N, Liu Y, Jin Z, Ji Z, Dai G
International journal of molecular sciences 2024 Feb 27;25(5)
International journal of molecular sciences 2024 Feb 27;25(5)
Growth Factors-Loaded Temperature-Sensitive Hydrogel as Biomimetic Mucus Attenuated Murine Ulcerative Colitis via Repairing the Mucosal Barriers.
Li D, Shangguan J, Yu F, Lin G, Pan H, Zhang M, Lin H, Chen B, Xu H, Hu S
ACS applied materials & interfaces 2024 Feb 14;16(6):7686-7699
ACS applied materials & interfaces 2024 Feb 14;16(6):7686-7699
Buyang Huanwu Decoction suppresses cardiac inflammation and fibrosis in mice after myocardial infarction through inhibition of the TLR4 signalling pathway.
Zhang G, Han X, Xu T, Liu M, Chen G, Xie L, Xu H, Hua Y, Pang M, Hu C, Wu Y, Liu B, Zhou Y
Journal of ethnopharmacology 2024 Feb 10;320:117388
Journal of ethnopharmacology 2024 Feb 10;320:117388
Halofuginone ameliorates the susceptibility to atrial fibrillation by activating the PI3K/Akt signaling pathway.
Xu F, Zhao X, Zhang J, Shen C
Journal of molecular histology 2024 Dec;55(6):1295-1306
Journal of molecular histology 2024 Dec;55(6):1295-1306
Geniposide alleviates heart failure with preserved ejection fraction in mice by regulating cardiac oxidative stress via MMP2/SIRT1/GSK3β pathway.
Han YL, Yan TT, Li HX, Chen SS, Zhang ZZ, Wang MY, Chen MJ, Chen YL, Yang XX, Wei LL, Duan YJ, Zhang S
Acta pharmacologica Sinica 2024 Dec;45(12):2567-2578
Acta pharmacologica Sinica 2024 Dec;45(12):2567-2578
α-Mangostin Attenuates Blood Pressure and Reverses Vascular Remodeling by Balancing ACE/AT1R and ACE2/Ang-(1-7)/MasR Axes in Ang II-Infused Hypertensive Mice.
Xue QQ, Liu CH, Zhang DY, Li MX, Li Y
Phytotherapy research : PTR 2024 Dec;38(12):5918-5929
Phytotherapy research : PTR 2024 Dec;38(12):5918-5929
Sec13 promotes glycolysis by inhibiting Ubqln1 mediated Pgm1 ubiquitination in ALI.
Wu D, Zhang H, Li F, Liu S, Wang Y, Zhang Z, Wang J, Wu Q
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167475
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167475
Pharmacological modulation of transglutaminase 2 in the unilateral ureteral obstruction mouse model.
Prat-Duran J, De Araujo IBBA, Juste N, Pinilla E, Rios FJ, Montezano AC, Touyz RM, Simonsen U, Nørregaard R, Buus NH
European journal of pharmacology 2024 Dec 5;984:177037
European journal of pharmacology 2024 Dec 5;984:177037
MicroRNA-668 alleviates renal fibrosis through PPARα/PGC-1α pathway.
Wang X, Gu Z, Huang Y, Wang J, Tang S, Yang X, Wang J
European journal of medical research 2024 Dec 28;29(1):631
European journal of medical research 2024 Dec 28;29(1):631
Tubuloside A alleviates postmyocardial infarction cardiac fibrosis by inhibiting TGM2: Involvement of inflammation and mitochondrial pathway apoptosis.
Sun R, Li H, Chen Y, Hu M, Wang J
International immunopharmacology 2024 Dec 25;143(Pt 1):113324
International immunopharmacology 2024 Dec 25;143(Pt 1):113324
Identification of key mitochondria-related genes and their potential crosstalk role with immune pattern in Idiopathic pulmonary fibrosis.
Huang J, Wang X, Zeng Y, Xu H, Zhang S, Ding Z, Guo R
Gene 2024 Dec 20;930:148840
Gene 2024 Dec 20;930:148840
Mechanistic Study of Purple Sweet Potato Anthocyanins: Multifaceted Anti-Fibrotic Effects and Targeting of PDGFRβ in Liver Fibrosis.
Dai J, Li H, Gou L, Tian Y, Cheng C, Yuan F, Xie J, Zhang L, Ji J, Zhang L, Wang X
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27861-27875
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27861-27875
Uni-directional release of ibuprofen from an asymmetric fibrous membrane enables effective peritendinous anti-adhesion.
Deng J, Yao Z, Wang S, Zhang X, Zhan L, Wang T, Yu W, Zeng J, Wu J, Fu S, Wu S, Ouyang Y, Huang C
Journal of controlled release : official journal of the Controlled Release Society 2024 Aug;372:251-264
Journal of controlled release : official journal of the Controlled Release Society 2024 Aug;372:251-264
Multiomics analysis of canine myocardium after circumferential pulmonary vein ablation: Effect of neuropeptide Y on long-term reinduction of atrial fibrillation.
Song Q, Zhang N, Zhang Y, Zhang A, Li H, Bai S, Shang L, Du J, Hou Y
Journal of cellular and molecular medicine 2024 Aug;28(15):e18582
Journal of cellular and molecular medicine 2024 Aug;28(15):e18582
Faecalibacterium prausnitzii-derived extracellular vesicles alleviate chronic colitis-related intestinal fibrosis by macrophage metabolic reprogramming.
Wang Y, Li L, Chen S, Yu Z, Gao X, Peng X, Ye Q, Li Z, Tan W, Chen Y
Pharmacological research 2024 Aug;206:107277
Pharmacological research 2024 Aug;206:107277
Lipoamide Attenuates Hypertensive Myocardial Hypertrophy Through PI3K/Akt-Mediated Nrf2 Signaling Pathway.
Cao H, Zhao L, Yuan Y, Liao C, Zeng W, Li A, Huang Q, Zhao Y, Fan Y, Jiang L, Song D, Li S, Zhang B
Journal of cardiovascular translational research 2024 Aug;17(4):910-922
Journal of cardiovascular translational research 2024 Aug;17(4):910-922
Design, Synthesis, and Evaluation of the Selective and Orally Active LSD1 Inhibitor with the Potential of Treating Heart Failure.
Huang MJ, Xu J, Qiao H, Zhao W, Huang L
Journal of medicinal chemistry 2024 Aug 8;67(15):13409-13434
Journal of medicinal chemistry 2024 Aug 8;67(15):13409-13434
Expression of insulin-like growth factor binding protein 5 in the vaginal wall tissues of older women with pelvic organ prolapse.
Duan Y, Chen Y, He Y, Gong R, Xia Z
Scientific reports 2024 Aug 7;14(1):18353
Scientific reports 2024 Aug 7;14(1):18353
miR-450a-2-3p targets ERK(1/2) to ameliorate ISO-induced cardiac fibrosis in mice.
Liu L, Luo F
Genes & nutrition 2024 Aug 19;19(1):16
Genes & nutrition 2024 Aug 19;19(1):16
Blocking CTLA-4 promotes pressure overload-induced heart failure via activating Th17 cells.
Shang AQ, Yu CJ, Bi X, Jiang WW, Zhao ML, Sun Y, Guan H, Zhang ZR
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 15;38(15):e23851
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 15;38(15):e23851
Zonisamide attenuates pressure overload-induced myocardial hypertrophy in mice through proteasome inhibition.
Wu Q, Liu WJ, Ma XY, Chang JS, Zhao XY, Liu YH, Yu XY
Acta pharmacologica Sinica 2024 Apr;45(4):738-750
Acta pharmacologica Sinica 2024 Apr;45(4):738-750
Schwann cell derived pleiotrophin stimulates fibroblast for proliferation and excessive collagen deposition in plexiform neurofibroma.
Tian Z, Du Z, Bai G, Gong Q, You Y, Xu G, Liu J, Xiao M, Wang Y, He Y
Cancer gene therapy 2024 Apr;31(4):627-640
Cancer gene therapy 2024 Apr;31(4):627-640
Chloroxine inhibits pancreatic cancer progression through targeted antagonization of the PI3K/AKT/mTOR signaling pathway.
Lin M, Xiao Y, Dai Y, Mao Y, Xu L, Zhang Q, Chen Z
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2024 Apr;26(4):951-965
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2024 Apr;26(4):951-965
Interleukin-22 inhibits cardiac fibrosis by regulating fibroblast metabolic reprogramming in myocardial infarction.
Liu F, Chen Y, Qin D, Qian C
Pathology, research and practice 2024 Apr;256:155256
Pathology, research and practice 2024 Apr;256:155256
STING deficiency alleviates ferroptosis through FPN1 stabilization in diabetic kidney disease.
Zhao QX, Yan SB, Wang F, Li XX, Shang GK, Zheng ZJ, Xiao J, Lin ZW, Li CB, Ji XP
Biochemical pharmacology 2024 Apr;222:116102
Biochemical pharmacology 2024 Apr;222:116102
CXCL4/CXCR3 axis regulates cardiac fibrosis by activating TGF-β1/Smad2/3 signaling in mouse viral myocarditis.
Wei J, Wang DF, Cui CC, Tan JJ, Peng MY, Lu HX
Immunity, inflammation and disease 2024 Apr;12(4):e1237
Immunity, inflammation and disease 2024 Apr;12(4):e1237
Intimomedial tears of the aorta heal by smooth muscle cell-mediated fibrosis without atherosclerosis.
Hassab AH, Hur DJ, Vallabhajosyula P, Tellides G, Assi R
JCI insight 2024 Apr 9;9(9)
JCI insight 2024 Apr 9;9(9)
Cell Senescence-Independent Changes of Human Skin Fibroblasts with Age.
Fullard N, Wordsworth J, Welsh C, Maltman V, Bascom C, Tasseff R, Isfort R, Costello L, Scanlan RL, Przyborski S, Shanley D
Cells 2024 Apr 9;13(8)
Cells 2024 Apr 9;13(8)
Sphingolipid metabolism controls mammalian heart regeneration.
Ji X, Chen Z, Wang Q, Li B, Wei Y, Li Y, Lin J, Cheng W, Guo Y, Wu S, Mao L, Xiang Y, Lan T, Gu S, Wei M, Zhang JZ, Jiang L, Wang J, Xu J, Cao N
Cell metabolism 2024 Apr 2;36(4):839-856.e8
Cell metabolism 2024 Apr 2;36(4):839-856.e8
AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis.
Zhao J, Yang T, Yi J, Hu H, Lai Q, Nie L, Liu M, Chu C, Yang J
iScience 2024 Apr 19;27(4):109321
iScience 2024 Apr 19;27(4):109321
LncRNA GAS5 restrains ISO-induced cardiac fibrosis by modulating mir-217 regulation of SIRT1.
Zhang YH, Sun TT, Liu ZH, Li X, Fan XF, Han LP
Scientific reports 2024 Apr 1;14(1):7652
Scientific reports 2024 Apr 1;14(1):7652
Echinacoside alleviates airway remodeling and inflammation in an ovalbumin-induced neonatal mouse model of asthma by modulating the SIRT1-NF-κB pathway.
Pan Y, Liu Y
Allergologia et immunopathologia 2023;51(4):71-77
Allergologia et immunopathologia 2023;51(4):71-77
hUMSCs Restore Uterine Function by Inhibiting Endometrial Fibrosis via Regulation of the MMP-9/TIMP-1 Ratio in CDDP-Induced Injury Rats.
Tang Y, Si Y, Liu C, Li C, Qu L, Liu Y, Fu Q, Luo Q
Stem cells international 2023;2023:8014052
Stem cells international 2023;2023:8014052
hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts.
Wang Y, Zhang Y, Lu B, Xi J, Ocansey DKW, Mao F, Hao D, Yan Y
Stem cells international 2023;2023:2828981
Stem cells international 2023;2023:2828981
Electric field promotes dermal fibroblast transdifferentiation through activation of RhoA/ROCK1 pathway.
Wang W, Huang W, Liu J, Zhang Z, Ji R, Wu C, Zhang J, Jiang X
International journal of medical sciences 2023;20(10):1326-1335
International journal of medical sciences 2023;20(10):1326-1335
Combining Porous Se@SiO(2) Nanocomposites and dECM Enhances the Myogenic Differentiation of Adipose-Derived Stem Cells.
Zhang YC, Yang YX, Liu Y, Liu XJ, Dai JH, Gao RS, Hu YY, Fei WY
International journal of nanomedicine 2023;18:7661-7676
International journal of nanomedicine 2023;18:7661-7676
Isoliensinine Attenuates Renal Fibrosis and Inhibits TGF-β1/Smad2/3 Signaling Pathway in Spontaneously Hypertensive Rats.
Yao M, Lian D, Wu M, Zhou Y, Fang Y, Zhang S, Zhang W, Yang Y, Li R, Chen H, Chen Y, Shen A, Peng J
Drug design, development and therapy 2023;17:2749-2762
Drug design, development and therapy 2023;17:2749-2762
Thymoquinone affects the gemcitabine sensitivity of pancreatic cancer by regulating collagen via hypoxia inducible factor-1α.
Zhao Z, Liu L, Chen H, Li S, Guo Y, Hou X, Yang J
Frontiers in pharmacology 2023;14:1138265
Frontiers in pharmacology 2023;14:1138265
Gastrodin attenuates renal injury and collagen deposition via suppression of the TGF-β1/Smad2/3 signaling pathway based on network pharmacology analysis.
Wen Y, Zhang X, Wei L, Wu M, Cheng Y, Zheng H, Shen A, Fu C, Ali F, Long L, Lu Y, Li J, Peng J
Frontiers in pharmacology 2023;14:1082281
Frontiers in pharmacology 2023;14:1082281
Melatonin influences the biological characteristics of keloid fibroblasts through the Erk and Smad signalling pathways.
Huang S, Deng W, Dong Y, Hu Z, Zhang Y, Wang P, Cao X, Chen M, Cheng P, Xu H, Zhu W, Tang B, Zhu J
Burns & trauma 2023;11:tkad005
Burns & trauma 2023;11:tkad005
S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.
Ping L, Zhi-Ming L, Bi-Shan Z, Lei Z, Bo Y, Yi-Chun Z, Ming-Jie W
Frontiers in cell and developmental biology 2023;11:1291170
Frontiers in cell and developmental biology 2023;11:1291170
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Ge L, Wang K, Lin H, Tao E, Xia W, Wang F, Mao C, Feng Y
Frontiers in bioengineering and biotechnology 2023;11:1129538
Frontiers in bioengineering and biotechnology 2023;11:1129538
Plasma polymerized nanoparticles are a safe platform for direct delivery of growth factor therapy to the injured heart.
Clayton ZE, Santos M, Shah H, Lu J, Chen S, Shi H, Kanagalingam S, Michael PL, Wise SG, Chong JJH
Frontiers in bioengineering and biotechnology 2023;11:1127996
Frontiers in bioengineering and biotechnology 2023;11:1127996
Sclareol attenuates liver fibrosis through SENP1-mediated VEGFR2 SUMOylation and inhibition of downstream STAT3 signaling.
Ge MX, Niu WX, Bao YY, Lu ZN, He HW
Phytotherapy research : PTR 2023 Sep;37(9):3898-3912
Phytotherapy research : PTR 2023 Sep;37(9):3898-3912
Mining host candidate regulators of schistosomiasis-induced liver fibrosis in response to artesunate therapy through transcriptomics approach.
Yuan Y, Lv X, Wu Y, Weng Y, Dai F, Ding H, Chen R, Zheng B, Zhao W, Tong Q, Ding J, Lou D, Lai Y, Chu X, Zhao L, Lu S, Kong Q
PLoS neglected tropical diseases 2023 Sep;17(9):e0011626
PLoS neglected tropical diseases 2023 Sep;17(9):e0011626
AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.
Yang T, Yang Q, Lai Q, Zhao J, Nie L, Liu S, Yang J, Chu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115195
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115195
The response and resistance to drugs in ovarian cancer cell lines in 2D monolayers and 3D spheroids.
Świerczewska M, Sterzyńska K, Ruciński M, Andrzejewska M, Nowicki M, Januchowski R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115152
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115152
Gentianella acuta-derived Gen-miR-1 suppresses myocardial fibrosis by targeting HAX1/HMG20A/Smads axis to attenuate inflammation in cardiac fibroblasts.
Zhang T, Zhang Y, Li S, Ge H, Song Q, Zhang Y, Yang G, Li A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154923
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154923
TRIM44 aggravates cardiac fibrosis after myocardial infarction via TAK1 stabilization.
Qian H, Lu Z, Hao C, Zhao Y, Bo X, Hu Y, Zhang Y, Yao Y, Ma G, Chen L
Cellular signalling 2023 Sep;109:110744
Cellular signalling 2023 Sep;109:110744
Riboflavin ameliorates pathological cardiac hypertrophy and fibrosis through the activation of short-chain acyl-CoA dehydrogenase.
Peng H, Xie M, Zhong X, Su Y, Qin X, Xu Q, Zhou S
European journal of pharmacology 2023 Sep 5;954:175849
European journal of pharmacology 2023 Sep 5;954:175849
Omentin-1 induces mechanically activated fibroblasts lipogenic differentiation through pkm2/yap/pparγ pathway to promote lung fibrosis resolution.
Zhang Y, Fu J, Li C, Chang Y, Li X, Cheng H, Qiu Y, Shao M, Han Y, Feng D, Yue S, Sun Z, Luo Z, Zhou Y
Cellular and molecular life sciences : CMLS 2023 Sep 28;80(10):308
Cellular and molecular life sciences : CMLS 2023 Sep 28;80(10):308
Calcineurin/NFATc3 pathway mediates myocardial fibrosis in diabetes by impairing enhancer of zeste homolog 2 of cardiac fibroblasts.
Zhang L, Liu HH, Yang F, Zhang ZY, Wu Y, Li F, Dang SP, Zhang ZY, Qian LL, Wang RX
BMC cardiovascular disorders 2023 Sep 21;23(1):474
BMC cardiovascular disorders 2023 Sep 21;23(1):474
Core fucosylation regulates alveolar epithelial cells senescence through activating of transforming growth factor-β pathway in pulmonary fibrosis.
Jiang Y, Wang Z, Hu J, Wang W, Zhang N, Gao L
Aging 2023 Sep 18;15(18):9572-9589
Aging 2023 Sep 18;15(18):9572-9589
Qingda granule ameliorates vascular remodeling and phenotypic transformation of adventitial fibroblasts via suppressing the TGF-β1/Smad2/3 pathway.
Wu M, Zhang S, Zhang W, Zhou Y, Guo Z, Fang Y, Yang Y, Shen Z, Lian D, Shen A, Peng J
Journal of ethnopharmacology 2023 Sep 15;313:116535
Journal of ethnopharmacology 2023 Sep 15;313:116535
Human adipose ECM alleviates radiation-induced skin fibrosis via endothelial cell-mediated M2 macrophage polarization.
Chinnapaka S, Yang KS, Surucu Y, Bengur FB, Arellano JA, Tirmizi Z, Malekzadeh H, Epperly MW, Hou W, Greenberger JS, Rubin JP, Ejaz A
iScience 2023 Sep 15;26(9):107660
iScience 2023 Sep 15;26(9):107660
Overexpression of KLF4 Suppresses Pulmonary Fibrosis through the HIF-1α/Endoplasmic Reticulum Stress Signaling Pathway.
Wei S, Qi F, Wu Y, Liu X
International journal of molecular sciences 2023 Sep 12;24(18)
International journal of molecular sciences 2023 Sep 12;24(18)
Buried penis: a histological and histochemical study of dartos fascia.
Zhang HY, Zhao GG, Song YT, Xiao KB, Li HF, Cui J
Asian journal of andrology 2023 Sep 1;25(5):632-636
Asian journal of andrology 2023 Sep 1;25(5):632-636
Increased Expression of Adipokines in Patients With Frozen Shoulder.
Qiao Y, Yao X, Zhao Y, Kang Y, Xu C, Zhao J, Zhao S
The American journal of sports medicine 2023 Oct;51(12):3261-3267
The American journal of sports medicine 2023 Oct;51(12):3261-3267
Molecular insights of a CBP/β-catenin-signaling inhibitor on nonalcoholic steatohepatitis-induced liver fibrosis and disorder.
Yamaji K, Iwabuchi S, Tokunaga Y, Hashimoto S, Yamane D, Toyama S, Kono R, Kitab B, Tsukiyama-Kohara K, Osawa Y, Hayashi Y, Hishima T, Tateno C, Kimura K, Okanoue T, Kohara M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115379
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115379
NKRF in Cardiac Fibroblasts Protects against Cardiac Remodeling Post-Myocardial Infarction via Human Antigen R.
Guo C, Ji W, Yang W, Deng Q, Zheng T, Wang Z, Sui W, Zhai C, Yu F, Xi B, Yu X, Xu F, Zhang Q, Zhang W, Kong J, Zhang M, Zhang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2303283
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2303283
Caveolin-1 scaffolding domain peptide prevents corpus cavernosum fibrosis and erectile dysfunction in bilateral cavernous nerve injury-induced rats.
Xi Y, Ge Y, Hu D, Xia T, Chen J, Zhang C, Cui Y, Xiao H
The journal of sexual medicine 2023 Oct 31;20(11):1274-1284
The journal of sexual medicine 2023 Oct 31;20(11):1274-1284
Glucose fluctuations aggravate myocardial fibrosis via activating the CaMKII/Stat3 signaling in type 2 diabtetes.
Zhang L, Liu HH, Yang F, Zhang ZY, Zhang ZY, Zhao XX, Qian LL, Dang SP, Wang RX
Diabetology & metabolic syndrome 2023 Oct 28;15(1):217
Diabetology & metabolic syndrome 2023 Oct 28;15(1):217
Substrate-dependent interaction of SPOP and RACK1 aggravates cardiac fibrosis following myocardial infarction.
Yang W, Zhuang Y, Wu H, Su S, Li Y, Wang C, Tian Z, Peng L, Zhang X, Liu J, Pei X, Yuan W, Hu X, Meng B, Li D, Zhang Y, Shan H, Pan Z, Lu Y
Cell chemical biology 2023 Oct 19;30(10):1248-1260.e4
Cell chemical biology 2023 Oct 19;30(10):1248-1260.e4
Blockade of IL-11 Trans-Signaling or JAK2/STAT3 Signaling Ameliorates the Profibrotic Effect of IL-11.
Ye W, Wang Q, Zhao L, Wang C, Zhang D, Zhou M, Chen F, Wang W, Zhu Z, Guo W, Liu Y, Zou H, Xue Y
Immunological investigations 2023 Nov;52(6):703-716
Immunological investigations 2023 Nov;52(6):703-716
Macrophage RAGE deficiency prevents myocardial fibrosis by repressing autophagy-mediated macrophage alternative activation.
He J, Wei L, Tan S, Liang B, Liu J, Lu L, Wang T, Wang J, Huang Y, Chen Z, Li H, Zhang L, Zhou Z, Cao Y, Ye X, Yang Z, Xian S, Wang L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23259
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23259
COL3A1, COL5A1 and COL6A2 serve as potential molecular biomarkers for osteoarthritis based on weighted gene co‑expression network analysis bioinformatics analysis.
Zhang Y, Niu Y, Peng Y, Pan X, Wang F
Experimental and therapeutic medicine 2023 Nov;26(5):540
Experimental and therapeutic medicine 2023 Nov;26(5):540
Hepatic macrophages play critical roles in the establishment and growth of hydatid cysts in the liver during Echinococcus granulosus sensu stricto infection.
Wang H, Yu Q, Wang M, Hou J, Wang M, Kang X, Hou X, Li D, Rousu Z, Jiang T, Li J, Wen H, Zhang C
PLoS neglected tropical diseases 2023 Nov;17(11):e0011746
PLoS neglected tropical diseases 2023 Nov;17(11):e0011746
Biomimetic nanoparticles loaded lutein functionalized by macrophage membrane for targeted amelioration pressure overload-induced cardiac fibrosis.
Guo T, Chen L, Li F, Cao Y, Li D, Xiong Q, Ling Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115579
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115579
Alpha lipoamide inhibits diabetic kidney fibrosis via improving mitochondrial function and regulating RXRα expression and activation.
Zhang HF, Liu HM, Xiang JY, Zhou XC, Wang D, Chen RY, Tan WL, Liang LQ, Liu LL, Shi MJ, Zhang F, Xiao Y, Zhou YX, Zhang T, Tang L, Guo B, Wang YY
Acta pharmacologica Sinica 2023 May;44(5):1051-1065
Acta pharmacologica Sinica 2023 May;44(5):1051-1065
Bioinformatics analysis and identification of dysregulated POSTN in the pathogenesis of keloid.
Xu H, Wang Z, Yang H, Zhu J, Hu Z
International wound journal 2023 May;20(5):1700-1711
International wound journal 2023 May;20(5):1700-1711
Schistosome egg antigen stimulates the secretion of miR-33-carrying extracellular vesicles from macrophages to promote hepatic stellate cell activation and liver fibrosis in schistosomiasis.
Qi X, Pu Y, Chen F, Dong L, Ma Y, Wang J, Yin G, Lu D, Chen X, Zhu J, Li Y, Zhou S, Su C
PLoS neglected tropical diseases 2023 May;17(5):e0011385
PLoS neglected tropical diseases 2023 May;17(5):e0011385
Pilose antler extract restores type I and III collagen to accelerate wound healing.
Li L, Ma Y, He G, Ma S, Wang Y, Sun Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114510
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114510
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
Zhou Y, Liu L, Jin B, Wu Y, Xu L, Chang X, Hu L, Wang G, Huang Y, Song L, Zhang T, Wang Y, Xiao Y, Zhang F, Shi M, Liu L, Wang T, Yan R, Guo B
Diabetes 2023 May 1;72(5):611-626
Diabetes 2023 May 1;72(5):611-626
The p53/miR-29a-3p axis mediates the antifibrotic effect of leonurine on angiotensin II-stimulated rat cardiac fibroblasts.
Xi T, Wang R, Pi D, Ouyang J, Yang J
Experimental cell research 2023 May 1;426(1):113556
Experimental cell research 2023 May 1;426(1):113556
Angiotensin II Type 1A Receptor Expressed in Smooth Muscle Cells is Required for Hypertensive Vascular Remodeling in Mice Infused With Angiotensin II.
Okuno K, Torimoto K, Cicalese SM, Preston K, Rizzo V, Hashimoto T, Coffman TM, Sparks MA, Eguchi S
Hypertension (Dallas, Tex. : 1979) 2023 Mar;80(3):668-677
Hypertension (Dallas, Tex. : 1979) 2023 Mar;80(3):668-677
Ginsenoside Re inhibits myocardial fibrosis by regulating miR-489/myd88/NF-κB pathway.
Sun J, Wang R, Chao T, Peng J, Wang C, Chen K
Journal of ginseng research 2023 Mar;47(2):218-227
Journal of ginseng research 2023 Mar;47(2):218-227
MetBil as a novel molecular regulator in ischemia-induced cardiac fibrosis via METTL3-mediated m6A modification.
Zhuang Y, Li T, Hu X, Xie Y, Pei X, Wang C, Li Y, Liu J, Tian Z, Zhang X, Peng L, Meng B, Wu H, Yuan W, Pan Z, Lu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22797
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22797
miR-124-3p improves mitochondrial function of renal tubular epithelial cells in db/db mice.
Liang L, Wo C, Yuan Y, Cao H, Tan W, Zhou X, Wang D, Chen R, Shi M, Zhang F, Xiao Y, Liu L, Zhou Y, Zhang T, Wang Y, Guo B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22794
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22794
Smooth muscle angiotensin II type 1A receptor is required for abdominal aortic aneurysm formation induced by angiotensin II plus β-aminopropionitrile.
Okuno K, Torimoto K, Cicalese SM, Hashimoto T, Sparks MA, Rizzo V, Eguchi S
Journal of molecular and cellular cardiology 2023 Mar;176:55-57
Journal of molecular and cellular cardiology 2023 Mar;176:55-57
Fibroblast-Derived Extracellular Vesicle-Packaged Long Noncoding RNA Upregulated in Diabetic Skin Enhances Keratinocyte MMP-9 Expression and Delays Diabetic Wound Healing.
Wu Y, Wu X, Wang J, Chen S, Chen H, Liu J, Zeng T, Hu M, Liang Y, Sun K, Yang C, Yan L, Ren M
Laboratory investigation; a journal of technical methods and pathology 2023 Mar;103(3):100019
Laboratory investigation; a journal of technical methods and pathology 2023 Mar;103(3):100019
Luteolin reduces cardiac damage caused by hyperlipidemia in Sprague-Dawley rats.
Dong M, Luo Y, Lan Y, He Q, Xu L, Pei Z
Heliyon 2023 Jun;9(6):e17613
Heliyon 2023 Jun;9(6):e17613
Evaluation of the effect of 3D-bioprinted gingival fibroblast-encapsulated ADM scaffolds on keratinized gingival augmentation.
Liu P, Li Q, Yang Q, Zhang S, Yi K, Zhang G, Tang Z
Journal of periodontal research 2023 Jun;58(3):564-574
Journal of periodontal research 2023 Jun;58(3):564-574
TGF-β-induced PI3K/AKT/mTOR pathway controls myofibroblast differentiation and secretory phenotype of valvular interstitial cells through the modulation of cellular senescence in a naturally occurring in vitro canine model of myxomatous mitral valve disease.
Tang Q, Markby GR, MacNair AJ, Tang K, Tkacz M, Parys M, Phadwal K, MacRae VE, Corcoran BM
Cell proliferation 2023 Jun;56(6):e13435
Cell proliferation 2023 Jun;56(6):e13435
Liensinine prevents ischemic injury following myocardial infarction via inhibition of Wnt/β‑catenin signaling activation.
Shen F, Wu C, Zhong X, Ma E, Peng J, Zhu W, Wo D, Ren DN
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114675
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114675
3D-printed hydrogel particles containing PRP laden with TDSCs promote tendon repair in a rat model of tendinopathy.
Li C, Wang J, Yang W, Yu K, Hong J, Ji X, Yao M, Li S, Lu J, Chen Y, Yan S, Wu H, Ma C, Yu X, Jiang G, Liu A
Journal of nanobiotechnology 2023 Jun 3;21(1):177
Journal of nanobiotechnology 2023 Jun 3;21(1):177
Therapeutic Effects of Long-Term Administration of Tranilast in an Animal Model for the Treatment of Fibroids.
Chuang TD, Munoz L, Quintanilla D, Boos D, Khorram O
International journal of molecular sciences 2023 Jun 21;24(13)
International journal of molecular sciences 2023 Jun 21;24(13)
Ovariectomy with simulated vaginal delivery to establish a rat model for pelvic organ prolapse.
Guo T, Du Z, Wang XQ, Lang JH, Sun ZJ
Connective tissue research 2023 Jul;64(4):376-388
Connective tissue research 2023 Jul;64(4):376-388
Decorin: a potential therapeutic candidate for ligamentum flavum hypertrophy by antagonizing TGF-β1.
Wang S, Qu Y, Fang X, Ding Q, Zhao H, Yu X, Xu T, Lu R, Jing S, Liu C, Wu H, Liu Y
Experimental & molecular medicine 2023 Jul;55(7):1413-1423
Experimental & molecular medicine 2023 Jul;55(7):1413-1423
hUMSCs Transplantation Regulates AMPK/NR4A1 Signaling Axis to Inhibit Ovarian Fibrosis in POI Rats.
Cui L, Bao H, Zhu W, Tang Y, Luo Q, Si Y, Fu Q, Jiang Z
Stem cell reviews and reports 2023 Jul;19(5):1449-1465
Stem cell reviews and reports 2023 Jul;19(5):1449-1465
Sacha inchi albumin delays skin-aging by alleviating inflammation, oxidative stress and regulating gut microbiota in d-galactose induced-aging mice.
Zeng J, An M, Tian W, Wang K, Du B, Li P
Journal of the science of food and agriculture 2023 Jul;103(9):4470-4480
Journal of the science of food and agriculture 2023 Jul;103(9):4470-4480
In situ gel-forming oil as rectally delivering platform of hydrophobic therapeutics for ulcerative colitis therapy.
Zhao Y, Xu J, Shangguan J, Pan H, Lu K, Hu S, Xu H
International journal of pharmaceutics 2023 Jul 25;642:123149
International journal of pharmaceutics 2023 Jul 25;642:123149
Different exercise training intensities prevent type 2 diabetes mellitus-induced myocardial injury in male mice.
Pei Z, Zhou R, Yao W, Dong S, Liu Y, Gao Z
iScience 2023 Jul 21;26(7):107080
iScience 2023 Jul 21;26(7):107080
Recombinant protein EBI3 attenuates Clonorchis sinensis-induced liver fibrosis by inhibiting hepatic stellate cell activation in mice.
Zhao L, Li J, Mo G, Cao D, Li C, Huang G, Jiang L, Chen G, Yao H, Peng X
Parasites & vectors 2023 Jul 21;16(1):246
Parasites & vectors 2023 Jul 21;16(1):246
Triptolide with hepatotoxicity and nephrotoxicity used in local delivery treatment of myocardial infarction by thermosensitive hydrogel.
Wang K, Zhu K, Zhu Z, Shao F, Qian R, Wang C, Dong H, Li Y, Gao Z, Zhao J
Journal of nanobiotechnology 2023 Jul 17;21(1):227
Journal of nanobiotechnology 2023 Jul 17;21(1):227
Resveratrol plays an anti-fibrotic and anti-autophagy role by stimulating miR-192-5p expression in urethral fibrosis.
Lv J, Zhang R, Li D, Liu Y
Functional & integrative genomics 2023 Jul 14;23(3):241
Functional & integrative genomics 2023 Jul 14;23(3):241
Qing Fei Hua Xian Decoction ameliorates bleomycin-induced pulmonary fibrosis by suppressing oxidative stress through balancing ACE-AngII-AT1R/ACE2-Ang-(1-7)-Mas axis.
Li RJ, Wu CY, Ke HL, Wang XP, Zhang YW
Iranian journal of basic medical sciences 2023 Jan;26(1):107-113
Iranian journal of basic medical sciences 2023 Jan;26(1):107-113
The combination of exercise and metformin inhibits TGF-β1/Smad pathway to attenuate myocardial fibrosis in db/db mice by reducing NF-κB-mediated inflammatory response.
Liu J, Lu J, Zhang L, Liu Y, Zhang Y, Gao Y, Yuan X, Xiang M, Tang Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114080
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114080
Cryptotanshinone modulates proliferation, apoptosis, and fibrosis through inhibiting AR and EGFR/STAT3 axis to ameliorate benign prostatic hyperplasia progression.
Wei P, Lin D, Zhang M, Luo C, Wu X, Deng B, Cui K, Chen Z
European journal of pharmacology 2023 Jan 5;938:175434
European journal of pharmacology 2023 Jan 5;938:175434
Epigenetic control of LncRNA NEAT1 enables cardiac fibroblast pyroptosis and cardiac fibrosis.
Ding JF, Zhou Y, Xu SS, Shi KH, Sun H, Tu B, Song K, Xuan HY, Sha JM, Zhao JY, Tao H
European journal of pharmacology 2023 Jan 5;938:175398
European journal of pharmacology 2023 Jan 5;938:175398
Berberin sustained-release nanoparticles were enriched in infarcted rat myocardium and resolved inflammation.
Zhu K, Yao Y, Wang K, Shao F, Zhu Z, Song Y, Zhou Z, Jiang D, Lan X, Qin C
Journal of nanobiotechnology 2023 Jan 28;21(1):33
Journal of nanobiotechnology 2023 Jan 28;21(1):33
Irisin ameliorates D-galactose-induced skeletal muscle fibrosis via the PI3K/Akt pathway.
Wu Y, Wu Y, Yu J, Zhang Y, Li Y, Fu R, Sun Y, Zhao K, Xiao Q
European journal of pharmacology 2023 Jan 15;939:175476
European journal of pharmacology 2023 Jan 15;939:175476
Comparative analysis of dermal collagen and lipids in cereblon ablated mice using a multimodal nonlinear optical system.
Park CW, Jeon S, Kwon SH, Jung JH, Seol JE, Park CS, Cho SK, Ko DK
Journal of biophotonics 2023 Feb;16(2):e202200139
Journal of biophotonics 2023 Feb;16(2):e202200139
Polyphenol-driven facile assembly of a nanosized acid fibroblast growth factor-containing coacervate accelerates the healing of diabetic wounds.
Tong MQ, Lu CT, Huang LT, Yang JJ, Yang ST, Chen HB, Xue PP, Luo LZ, Yao Q, Xu HL, Zhao YZ
Acta biomaterialia 2023 Feb;157:467-486
Acta biomaterialia 2023 Feb;157:467-486
SUMO1 regulates post-infarct cardiac repair based on cellular heterogeneity.
Liu Z, Liu X, Liu L, Wang Y, Zheng J, Li L, Li S, Zhang H, Ni J, Ma C, Gao X, Bian X, Fan G
Journal of pharmaceutical analysis 2023 Feb;13(2):170-186
Journal of pharmaceutical analysis 2023 Feb;13(2):170-186
The UDPase ENTPD5 regulates ER stress-associated renal injury by mediating protein N-glycosylation.
Xu L, Zhou Y, Wang G, Bo L, Jin B, Dai L, Lu Q, Cai X, Hu L, Liu L, Wu Y, Chang X, Huang Y, Song L, Zhang T, Wang Y, Xiao Y, Zhang F, Liu L, Shi M, Wang T, Guo B
Cell death & disease 2023 Feb 27;14(2):166
Cell death & disease 2023 Feb 27;14(2):166
Old age promotes retinal fibrosis in choroidal neovascularization through circulating fibrocytes and profibrotic macrophages.
Yi C, Liu J, Deng W, Luo C, Qi J, Chen M, Xu H
Journal of neuroinflammation 2023 Feb 23;20(1):45
Journal of neuroinflammation 2023 Feb 23;20(1):45
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction.
Wang T, Yu M, Li H, Qin S, Ren W, Ma Y, Bo W, Xi Y, Cai M, Tian Z
International journal of molecular sciences 2023 Feb 19;24(4)
International journal of molecular sciences 2023 Feb 19;24(4)
Stomatin-like protein 2 deficiency exacerbates adverse cardiac remodeling.
Hu Y, Jiang H, Xu Y, Chen G, Fan R, Zhou Y, Liu Y, Yao Y, Liu R, Chen W, Zhang K, Chen X, Wang R, Qiu Z
Cell death discovery 2023 Feb 14;9(1):63
Cell death discovery 2023 Feb 14;9(1):63
Estrogen inhibits the differentiation of fibroblasts induced by high stiffness matrix by enhancing DNMT1 expression.
Zhao Z, Huang G, He Y, Zuo X, Han W, Li H
Tissue & cell 2023 Dec;85:102207
Tissue & cell 2023 Dec;85:102207
Single-cell analysis reveals lysyl oxidase (Lox)(+) fibroblast subset involved in cardiac fibrosis of diabetic mice.
Li H, Zhu X, Cao X, Lu Y, Zhou J, Zhang X
Journal of advanced research 2023 Dec;54:223-237
Journal of advanced research 2023 Dec;54:223-237
Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics.
Huang Y, Luo W, Chen S, Su H, Zhu W, Wei Y, Qiu Y, Long Y, Shi Y, Wei J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155117
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155117
Multi-omics analysis reveals the mechanism of action of ophiopogonin D against pulmonary fibrosis.
Bao S, Chen T, Chen J, Zhang J, Zhang G, Hui Y, Li J, Yan S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155078
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155078
Liensinine improves AngII-induced vascular remodeling via MAPK/TGF-β1/Smad2/3 signaling.
Jia P, Chen D, Zhu Y, Wang M, Zeng J, Zhang L, Cai Q, Lian D, Zhao C, Xu Y, Chu J, Lin S, Peng J, Lin W
Journal of ethnopharmacology 2023 Dec 5;317:116768
Journal of ethnopharmacology 2023 Dec 5;317:116768
TrxR/Trx inhibitor butaselen ameliorates pulmonary fibrosis by suppressing NF-κB/TGF-β1/Smads signaling.
Chen Y, Yin H, Sun J, Zhang G, Zhang Y, Zeng H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115822
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115822
Exploring the Role of Lycium barbarum Polysaccharide in Corneal Injury Repair and Investigating the Relevant Mechanisms through In Vivo and In Vitro Experiments.
Liu Q, Nan Y, Yang Y, Li X, Jiang W, Jiao T, Li J, Jia X, Ye M, Niu Y, Yuan L
Molecules (Basel, Switzerland) 2023 Dec 20;29(1)
Molecules (Basel, Switzerland) 2023 Dec 20;29(1)
Profibrotic role of transcription factor SP1 in cross-talk between fibroblasts and M2 macrophages.
Feng P, Che Y, Gao C, Chu X, Li Z, Li L, Li J, Gao J, Dong Y
iScience 2023 Dec 15;26(12):108484
iScience 2023 Dec 15;26(12):108484
Effect of a New Hyaluronic Acid Hydrogel Dermal Filler Cross-Linked With Lysine Amino Acid for Skin Augmentation and Rejuvenation.
Guo Y, Wei W, Wang H, Li Q, Wei C, Zhang J, Jin P
Aesthetic surgery journal 2023 Dec 14;44(1):NP87-NP97
Aesthetic surgery journal 2023 Dec 14;44(1):NP87-NP97
Oncogenic KRAS Drives Lipofibrogenesis to Promote Angiogenesis and Colon Cancer Progression.
Hsu WH, LaBella KA, Lin Y, Xu P, Lee R, Hsieh CE, Yang L, Zhou A, Blecher JM, Wu CJ, Lin K, Shang X, Jiang S, Spring DJ, Xia Y, Chen P, Shen JP, Kopetz S, DePinho RA
Cancer discovery 2023 Dec 12;13(12):2652-2673
Cancer discovery 2023 Dec 12;13(12):2652-2673
Infused juice concentrate of Japanese plum Prunus mume attenuates inflammatory vascular remodeling in a mouse model of hypertension induced by angiotensin II.
Okuno K, Torimoto K, Kuroda R, Cicalese SM, Okuno Y, Kono R, Marumoto S, Utsunomiya H, Eguchi S
Hypertension research : official journal of the Japanese Society of Hypertension 2023 Aug;46(8):1923-1933
Hypertension research : official journal of the Japanese Society of Hypertension 2023 Aug;46(8):1923-1933
sST2: A Bridge Between Sirt1/p53/p21 Signal-Induced Senescence and TGF-β1/Smad2/3 Regulation of Cardiac Fibrosis in Mouse Viral Myocarditis.
Tan J, Wei J, Lu H
Inflammation 2023 Aug;46(4):1305-1317
Inflammation 2023 Aug;46(4):1305-1317
Matrix stiffness-induced α-tubulin acetylation is required for skin fibrosis formation through activation of Yes-associated protein.
Wen D, Gao Y, Liu Y, Ho C, Sun J, Huang L, Liu Y, Li Q, Zhang Y
MedComm 2023 Aug;4(4):e319
MedComm 2023 Aug;4(4):e319
The adipose-derived stem cell peptide ADSCP2 alleviates hypertrophic scar fibrosis via binding with pyruvate carboxylase and remodeling the metabolic landscape.
Li J, Yin Y, Zou J, Zhang E, Li Q, Chen L, Li J
Acta physiologica (Oxford, England) 2023 Aug;238(4):e14010
Acta physiologica (Oxford, England) 2023 Aug;238(4):e14010
TRPA1 deficiency attenuates cardiac fibrosis via regulating GRK5/NFAT signaling in diabetic rats.
Wang M, Zhao M, Xu S, Zheng Z, Zhang J, Pan W, Yin Z, Liu J, Wei C, Wan J, Xu Y
Biochemical pharmacology 2023 Aug;214:115671
Biochemical pharmacology 2023 Aug;214:115671
M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation.
Sun J, Ju F, Jin J, Wang HL, Li ZJ, Sun YC, Chen QZ, Yang QQ, Tan J, Zhou YL
Small (Weinheim an der Bergstrasse, Germany) 2023 Aug;19(33):e2300326
Small (Weinheim an der Bergstrasse, Germany) 2023 Aug;19(33):e2300326
Eicosapentaenoic Acid Preserves Mitochondrial Quality and Attenuates Cardiac Remodeling After Myocardial Infarction in Rats.
Kobara M, Shiraishi T, Noda K, Toba H, Nakata T
Journal of cardiovascular translational research 2023 Aug;16(4):816-827
Journal of cardiovascular translational research 2023 Aug;16(4):816-827
Celastrol relieves myocardial infarction-induced cardiac fibrosis by inhibiting NLRP3 inflammasomes in rats.
Fan J, Ren M, Chen W, Wang H, He Y
International immunopharmacology 2023 Aug;121:110511
International immunopharmacology 2023 Aug;121:110511
Tough Gelatin Hydrogel for Tissue Engineering.
Yuan X, Zhu Z, Xia P, Wang Z, Zhao X, Jiang X, Wang T, Gao Q, Xu J, Shan D, Guo B, Yao Q, He Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(24):e2301665
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(24):e2301665
NPRC deletion attenuates cardiac fibrosis in diabetic mice by activating PKA/PKG and inhibiting TGF-β1/Smad pathways.
Meng L, Lu Y, Wang X, Cheng C, Xue F, Xie L, Zhang Y, Sui W, Zhang M, Zhang Y, Zhang C
Science advances 2023 Aug 2;9(31):eadd4222
Science advances 2023 Aug 2;9(31):eadd4222
Activating α7nAChR helps post-myocardial infarction healing by regulating macrophage polarization via the STAT3 signaling pathway.
Niu XH, Liu RH, Lv X, He RL, Lv FZ, Wu SJ, Li XQ, Li L, Lin JF
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Apr;72(4):879-892
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Apr;72(4):879-892
TSG-6 inhibits hypertrophic scar fibroblast proliferation by regulating IRE1α/TRAF2/NF-κB signalling.
Ma L, Hua L, Yu W, Ke L, Li LY
International wound journal 2023 Apr;20(4):1008-1019
International wound journal 2023 Apr;20(4):1008-1019
Peptide deregulated in hypertrophic scar-1 alleviates hypertrophic scar fibrosis by targeting focal adhesion kinase and pyruvate kinase M2 and remodeling the metabolic landscape.
Li J, Yin Y, Zhang E, Gui M, Chen L, Li J
International journal of biological macromolecules 2023 Apr 30;235:123809
International journal of biological macromolecules 2023 Apr 30;235:123809
Two-Pore-Domain Potassium Channel TREK-1 Mediates Pulmonary Fibrosis through Macrophage M2 Polarization and by Direct Promotion of Fibroblast Differentiation.
Zhang Y, Fu J, Han Y, Feng D, Yue S, Zhou Y, Luo Z
Biomedicines 2023 Apr 26;11(5)
Biomedicines 2023 Apr 26;11(5)
Suppression of SMOC2 alleviates myocardial fibrosis via the ILK/p38 pathway.
Rui H, Zhao F, Yuhua L, Hong J
Frontiers in cardiovascular medicine 2022;9:951704
Frontiers in cardiovascular medicine 2022;9:951704
Research on the Mechanism and Prevention of Hypertension Caused by Apatinib Through the RhoA/ROCK Signaling Pathway in a Mouse Model of Gastric Cancer.
Wang W, He Q, Li C, Zhuang C, Zhang H, Wang Q, Fan X, Qi M, Sun R, Yu J
Frontiers in cardiovascular medicine 2022;9:873829
Frontiers in cardiovascular medicine 2022;9:873829
MCC950, a Selective NLRP3 Inhibitor, Attenuates Adverse Cardiac Remodeling Following Heart Failure Through Improving the Cardiometabolic Dysfunction in Obese Mice.
Wang M, Zhao M, Yu J, Xu Y, Zhang J, Liu J, Zheng Z, Ye J, Wang Z, Ye D, Feng Y, Xu S, Pan W, Wei C, Wan J
Frontiers in cardiovascular medicine 2022;9:727474
Frontiers in cardiovascular medicine 2022;9:727474
Senescent renal tubular epithelial cells activate fibroblasts by secreting Shh to promote the progression of diabetic kidney disease.
Wang D, Yin L, Chen R, Tan W, Liang L, Xiang J, Zhang H, Zhou X, Deng H, Guo B, Wang Y
Frontiers in medicine 2022;9:1018298
Frontiers in medicine 2022;9:1018298
Loureirin A Exerts Antikeloid Activity by Antagonizing the TGF-β1/Smad Signalling Pathway.
Ma H, Duan X, Zhang R, Li H, Guo Y, Tian Y, Huang M, Chen G, Wang Z, Li L
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8661288
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8661288
The Traditional Chinese Medicine Formula FTZ Protects against Cardiac Fibrosis by Suppressing the TGFβ1-Smad2/3 Pathway.
Zhang Y, Wang D, Wu K, Shao X, Diao H, Wang Z, Sun M, Huang X, Li Y, Tang X, Yan M, Guo J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5642307
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5642307
Mechanism of Action of Zhi Gan Cao Decoction for Atrial Fibrillation and Myocardial Fibrosis in a Mouse Model of Atrial Fibrillation: A Network Pharmacology-Based Study.
Gao L, Kan C, Chen X, Xu S, Shi K
Computational and mathematical methods in medicine 2022;2022:4525873
Computational and mathematical methods in medicine 2022;2022:4525873
MicroRNA-325-3p Targets Human Epididymis Protein 4 to Relieve Right Ventricular Fibrosis in Rats with Pulmonary Arterial Hypertension.
Tang Y, Huo X, Liu J, Tang Y, Zhang M, Xie W, Zheng Z, He J, Lian J
Cardiovascular therapeutics 2022;2022:4382999
Cardiovascular therapeutics 2022;2022:4382999
Eugenol-Preconditioned Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Antioxidant Capacity of Tendon Stem Cells In Vitro and In Vivo.
Li X, Su Z, Shen K, Wang Q, Xu C, Wang F, Zhang Y, Jiang D
Oxidative medicine and cellular longevity 2022;2022:3945195
Oxidative medicine and cellular longevity 2022;2022:3945195
Fufang Xueshuantong Improves Diabetic Cardiomyopathy by Regulating the Wnt/β-Catenin Pathway.
Peng M, Liu H, Ji Q, Ma P, Niu Y, Ning S, Sun H, Pang X, Yang Y, Zhang Y, Han J, Hao G
International journal of endocrinology 2022;2022:3919161
International journal of endocrinology 2022;2022:3919161
p16(INK4a) Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin.
Liang Y, Gu T, Peng S, Lin Y, Liu J, Wang X, Huang X, Zhang X, Zhu J, Zhao L, Fan C, Wang G, Gu X, Lin J
Oxidative medicine and cellular longevity 2022;2022:3415528
Oxidative medicine and cellular longevity 2022;2022:3415528
Silencing of TLR4 Inhibits Atrial Fibrosis and Susceptibility to Atrial Fibrillation via Downregulation of NLRP3-TGF-β in Spontaneously Hypertensive Rats.
Ge C, Zhao Y, Liang Y, He Y
Disease markers 2022;2022:2466150
Disease markers 2022;2022:2466150
Tissue Kallikrein Protects Rat Prostate against the Inflammatory Damage in a Chronic Autoimmune Prostatitis Model via Restoring Endothelial Function in a Bradykinin Receptor B2-Dependent Way.
Zhang M, Lin D, Luo C, Wei P, Cui K, Chen Z
Oxidative medicine and cellular longevity 2022;2022:1247806
Oxidative medicine and cellular longevity 2022;2022:1247806
The conditioned medium from mesenchymal stromal cells pretreated with proinflammatory cytokines promote fibroblasts migration and activation.
Liu C, Wang C, Yang F, Lu Y, Du P, Hu K, Yin X, Zhao P, Lu G
PloS one 2022;17(4):e0265049
PloS one 2022;17(4):e0265049
Keloid Patient Plasma-Derived Exosomal hsa_circ_0020792 Promotes Normal Skin Fibroblasts Proliferation, Migration, and Fibrogenesis via Modulating miR-193a-5p and Activating TGF-β1/Smad2/3 Signaling.
Hu H, Mao G, Zheng J, Guo F
Drug design, development and therapy 2022;16:4223-4234
Drug design, development and therapy 2022;16:4223-4234
Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics.
Li Y, Li C, Xiong Y, Fang B, Lin X, Huang Q
Drug design, development and therapy 2022;16:1713-1729
Drug design, development and therapy 2022;16:1713-1729
STAMP2 Attenuates Cardiac Dysfunction and Insulin Resistance in Diabetic Cardiomyopathy via NMRAL1-Mediated NF-κB Inhibition in Type 2 Diabetic Rats.
Gao Z, Ti Y, Lu B, Song FQ, Zhang L, Hu BA, Xie JY, Zhang W, Han L, Zhong M
Diabetes, metabolic syndrome and obesity : targets and therapy 2022;15:3219-3229
Diabetes, metabolic syndrome and obesity : targets and therapy 2022;15:3219-3229
Phosphatidylethanolamine-binding protein 4 deficiency exacerbates carbon tetrachloride-induced liver fibrosis by regulating the NF-κB signaling pathway.
Luo Q, Ling Y, Li Y, Qu X, Shi Q, Zheng S, Li Y, Huang Y, Zhou X
Frontiers in pharmacology 2022;13:964829
Frontiers in pharmacology 2022;13:964829
NOX1 promotes myocardial fibrosis and cardiac dysfunction via activating the TLR2/NF-κB pathway in diabetic cardiomyopathy.
Zhang D, Li Y, Wang W, Lang X, Zhang Y, Zhao Q, Yan J, Zhang Y
Frontiers in pharmacology 2022;13:928762
Frontiers in pharmacology 2022;13:928762
Metformin Improves the Senescence of Renal Tubular Epithelial Cells in a High-Glucose State Through E2F1.
Liang D, Li Z, Feng Z, Yuan Z, Dai Y, Wu X, Zhang F, Wang Y, Zhou Y, Liu L, Shi M, Xiao Y, Guo B
Frontiers in pharmacology 2022;13:926211
Frontiers in pharmacology 2022;13:926211
QiShenYiQi Pill Ameliorates Cardiac Fibrosis After Pressure Overload-Induced Cardiac Hypertrophy by Regulating FHL2 and the Macrophage RP S19/TGF-β1 Signaling Pathway.
Anwaier G, Xie TT, Pan CS, Li AQ, Yan L, Wang D, Chen FK, Weng DZ, Sun K, Chang X, Fan JY, Han JY, Liu J
Frontiers in pharmacology 2022;13:918335
Frontiers in pharmacology 2022;13:918335
BMP-7 Upregulates Id2 Through the MAPK Signaling Pathway to Improve Diabetic Tubulointerstitial Fibrosis and the Intervention of Oxymatrine.
Xiao Y, Liang D, Li Z, Feng Z, Yuan Z, Zhang F, Wang Y, Zhou Y, Shi M, Liu L, Xiao Y, Guo B
Frontiers in pharmacology 2022;13:900346
Frontiers in pharmacology 2022;13:900346
Extracellular Matrix-Oriented Proteomic Analysis of Periodontal Ligament Under Mechanical Stress.
Thant L, Kaku M, Kakihara Y, Mizukoshi M, Kitami M, Arai M, Kitami K, Kobayashi D, Yoshida Y, Maeda T, Saito I, Uoshima K, Saeki M
Frontiers in physiology 2022;13:899699
Frontiers in physiology 2022;13:899699
A Novel miRNA From Egg-Derived Exosomes of Schistosoma japonicum Promotes Liver Fibrosis in Murine Schistosomiasis.
Wang Y, Gong W, Zhou H, Hu Y, Wang L, Shen Y, Yu G, Cao J
Frontiers in immunology 2022;13:860807
Frontiers in immunology 2022;13:860807
Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics.
Lin X, Wei Y, Li Y, Xiong Y, Fang B, Li C, Huang Q, Huang R, Wei J
Frontiers in pharmacology 2022;13:801982
Frontiers in pharmacology 2022;13:801982
Farrerol prevents Angiotensin II-induced cardiac remodeling in vivo and in vitro.
He J, Xu D, Wang L, Yu X
Frontiers in pharmacology 2022;13:1079251
Frontiers in pharmacology 2022;13:1079251
Administration of USP7 inhibitor P22077 inhibited cardiac hypertrophy and remodeling in Ang II-induced hypertensive mice.
Gu YH, Ren KW, Wang Y, Wang SH, Yu XH, Xu LW, Li HH, Bi HL
Frontiers in pharmacology 2022;13:1021361
Frontiers in pharmacology 2022;13:1021361
Lycorine Inhibits Hypertrophic Scar Formation by Inducing ROS-Mediated Apoptosis.
Dong Y, Lv D, Zhao Z, Xu Z, Hu Z, Tang B
Frontiers in bioengineering and biotechnology 2022;10:892015
Frontiers in bioengineering and biotechnology 2022;10:892015
Transcriptomic analysis supports collective endometrial cell migration in the pathogenesis of adenomyosis.
Zhai J, Li S, Sen S, Vallvé-Juanico J, Irwin JC, Vo KC, Wan J, Du Y, Chen ZJ, Giudice LC
Reproductive biomedicine online 2022 Sep;45(3):519-530
Reproductive biomedicine online 2022 Sep;45(3):519-530
Substitution of SERCA2 Cys(674) aggravates cardiac fibrosis by promoting the transformation of cardiac fibroblasts to cardiac myofibroblasts.
Huang X, Lin X, Wang L, Xie Y, Que Y, Li S, Hu P, Tong X
Biochemical pharmacology 2022 Sep;203:115164
Biochemical pharmacology 2022 Sep;203:115164
LARP6 Regulates Keloid Fibroblast Proliferation, Invasion, and Ability to Synthesize Collagen.
Chen L, Su Y, Yin B, Li S, Cheng X, He Y, Jia C
The Journal of investigative dermatology 2022 Sep;142(9):2395-2405.e7
The Journal of investigative dermatology 2022 Sep;142(9):2395-2405.e7
Generation of cost-effective MXene@polydopamine-decorated chitosan nanofibrous wound dressing for promoting wound healing.
Li H, Dai J, Yi X, Cheng F
Biomaterials advances 2022 Sep;140:213055
Biomaterials advances 2022 Sep;140:213055
Tubular IKKβ Deletion Alleviates Acute Ischemic Kidney Injury and Facilitates Tissue Regeneration.
Dahlke E, Engmann T, Anan Y, Häsler R, Solinas G, Theilig F
International journal of molecular sciences 2022 Sep 5;23(17)
International journal of molecular sciences 2022 Sep 5;23(17)
Atrial myocyte-derived exosomal microRNA contributes to atrial fibrosis in atrial fibrillation.
Hao H, Yan S, Zhao X, Han X, Fang N, Zhang Y, Dai C, Li W, Yu H, Gao Y, Wang D, Gao Q, Duan Y, Yuan Y, Li Y
Journal of translational medicine 2022 Sep 5;20(1):407
Journal of translational medicine 2022 Sep 5;20(1):407
Intact Fibroblast Growth Factor 23 Regulates Chronic Kidney Disease-Induced Myocardial Fibrosis by Activating the Sonic Hedgehog Signaling Pathway.
Li L, Gan H
Journal of the American Heart Association 2022 Sep 20;11(18):e026365
Journal of the American Heart Association 2022 Sep 20;11(18):e026365
Collagen and elastic fiber remodeling in the pregnant mouse myometrium†.
Ouellette A, Mahendroo M, Nallasamy S
Biology of reproduction 2022 Sep 12;107(3):741-751
Biology of reproduction 2022 Sep 12;107(3):741-751
The Apelin-APJ axis alleviates LPS-induced pulmonary fibrosis and endothelial mesenchymal transformation in mice by promoting Angiotensin-Converting Enzyme 2.
Wang H, Cong L, Yin X, Zhang N, Zhu M, Sun T, Fan J, Xue F, Fan X, Gong Y
Cellular signalling 2022 Oct;98:110418
Cellular signalling 2022 Oct;98:110418
Dihydroartemisinin suppresses renal fibrosis in mice by inhibiting DNA-methyltransferase 1 and increasing Klotho.
Zhou W, Chen MM, Liu HL, Si ZL, Wu WH, Jiang H, Wang LX, Vaziri ND, An XF, Su K, Chen C, Tan NH, Zhang ZH
Acta pharmacologica Sinica 2022 Oct;43(10):2609-2623
Acta pharmacologica Sinica 2022 Oct;43(10):2609-2623
In situ hydrogel capturing nitric oxide microbubbles accelerates the healing of diabetic foot.
Zhao Y, Luo L, Huang L, Zhang Y, Tong M, Pan H, Shangguan J, Yao Q, Xu S, Xu H
Journal of controlled release : official journal of the Controlled Release Society 2022 Oct;350:93-106
Journal of controlled release : official journal of the Controlled Release Society 2022 Oct;350:93-106
Epididymal white adipose tissue promotes angiotensin II-induced cardiac fibrosis in an exosome-dependent manner.
Su M, Li W, Yuan Y, Liu S, Liang C, Liu HE, Zhang R, Liu Y, Sun LI, Wei Y, Li C, Han X, Hao H, Zhao X, Luo Y, Yan S, Pan Z, Li Y
Translational research : the journal of laboratory and clinical medicine 2022 Oct;248:51-67
Translational research : the journal of laboratory and clinical medicine 2022 Oct;248:51-67
Endophilin A2 protects against renal fibrosis by targeting TGF-β/Smad signaling.
Mai X, Shang J, Chen Q, Gu S, Hong Y, Zhou J, Zhang M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22603
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22603
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Zhou W, Fu Y, Xu JS
Molecules (Basel, Switzerland) 2022 Nov 15;27(22)
Molecules (Basel, Switzerland) 2022 Nov 15;27(22)
Cell contractility and focal adhesion kinase control circumferential arterial stiffness.
Roberts E, Xu T, Assoian RK
Vascular biology (Bristol, England) 2022 Nov 1;4(1):28-39
Vascular biology (Bristol, England) 2022 Nov 1;4(1):28-39
Gaseous signal molecule SO(2) regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.
Zhao J, Wu Q, Yang T, Nie L, Liu S, Zhou J, Chen J, Jiang Z, Xiao T, Yang J, Chu C
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2022 Nov 1;26(6):541-556
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2022 Nov 1;26(6):541-556
Loss of RTN3 phenocopies chronic kidney disease and results in activation of the IGF2-JAK2 pathway in proximal tubular epithelial cells.
Fan LL, Du R, Liu JS, Jin JY, Wang CY, Dong Y, He WX, Yan RQ, Xiang R
Experimental & molecular medicine 2022 May;54(5):653-661
Experimental & molecular medicine 2022 May;54(5):653-661
Metabotropic glutamate receptor 5 blockade attenuates pathological cardiac remodelling in pulmonary arterial hypertension.
Mprah R, Ma Y, Adzika GK, Ndzie Noah ML, Adekunle AO, Duah M, Adu-Amankwaah J, Wowui PI, Okwuma JD, Qiao W, Wang C
Clinical and experimental pharmacology & physiology 2022 May;49(5):558-566
Clinical and experimental pharmacology & physiology 2022 May;49(5):558-566
Effects of thymoquinone against angiotensin II‑induced cardiac damage in apolipoprotein E‑deficient mice.
Zhang L, Zhang H, Ma J, Wang Y, Pei Z, Ding H
International journal of molecular medicine 2022 May;49(5)
International journal of molecular medicine 2022 May;49(5)
Radix ranunculus temate saponins sensitizes ovarian cancer to Taxol via upregulation of miR-let-7b.
You K, Liu Y, Chen L, Ye H, Lin W
Experimental and therapeutic medicine 2022 May;23(5):315
Experimental and therapeutic medicine 2022 May;23(5):315
Near-infrared Nrf2 activator IR-61 dye alleviates radiation-induced lung injury.
Zheng J, Wang Y, Wang Z, Chen W, Luo M, Zhang C, Wang Y, Chen L, Wu F, Yang W, Yang Z, Wang Y, Shi C
Free radical research 2022 May-Jun;56(5-6):411-426
Free radical research 2022 May-Jun;56(5-6):411-426
EP3 enhances adhesion and cytotoxicity of NK cells toward hepatic stellate cells in a murine liver fibrosis model.
Tao X, Zhang R, Du R, Yu T, Yang H, Li J, Wang Y, Liu Q, Zuo S, Wang X, Lazarus M, Zhou L, Wang B, Yu Y, Shen Y
The Journal of experimental medicine 2022 May 2;219(5)
The Journal of experimental medicine 2022 May 2;219(5)
Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis.
Qi W, Li X, Ren Y, Liu X, Fu H, Wang X, Li X, Xiong J, Zheng Q, Cai D, Liang F
Chinese medicine 2022 May 17;17(1):57
Chinese medicine 2022 May 17;17(1):57
Upregulation of Periostin Through CREB Participates in Myocardial Infarction-induced Myocardial Fibrosis.
Xue K, Chen S, Chai J, Yan W, Zhu X, Dai H, Wang W
Journal of cardiovascular pharmacology 2022 May 1;79(5):687-697
Journal of cardiovascular pharmacology 2022 May 1;79(5):687-697
Optimization of the saffron compound essence formula and its effect on preventing skin photoaging.
Li Q, Liu L, Jiang S, Xu Z, Lin S, Tong Y, Wang P
Journal of cosmetic dermatology 2022 Mar;21(3):1251-1262
Journal of cosmetic dermatology 2022 Mar;21(3):1251-1262
MicroRNA-24-3p alleviates cardiac fibrosis by suppressing cardiac fibroblasts mitophagy via downregulating PHB2.
Zhang Y, Wang Z, Lan D, Zhao J, Wang L, Shao X, Wang D, Wu K, Sun M, Huang X, Yan M, Liang H, Rong X, Diao H, Guo J
Pharmacological research 2022 Mar;177:106124
Pharmacological research 2022 Mar;177:106124
Injectable recombinant human collagen-derived material with high cell adhesion activity limits adverse remodelling and improves pelvic floor function in pelvic floor dysfunction rats.
Li H, You S, Yang X, Liu S, Hu L
Biomaterials advances 2022 Mar;134:112715
Biomaterials advances 2022 Mar;134:112715
Daidzein suppresses TGF-β1-induced cardiac fibroblast activation via the TGF-β1/SMAD2/3 signaling pathway.
Shu J, Hu L, Wu Y, Chen L, Huang K, Wang Z, Liang M
European journal of pharmacology 2022 Mar 15;919:174805
European journal of pharmacology 2022 Mar 15;919:174805
Transition of autophagy and apoptosis in fibroblasts depends on dominant expression of HIF-1α or p53.
Li M, Su Y, Gao X, Yu J, Wang Z, Wang X
Journal of Zhejiang University. Science. B 2022 Mar 15;23(3):204-217
Journal of Zhejiang University. Science. B 2022 Mar 15;23(3):204-217
Effect of ALDH1A1 Gene Knockout on Drug Resistance in Paclitaxel and Topotecan Resistant Human Ovarian Cancer Cell Lines in 2D and 3D Model.
Nowacka M, Ginter-Matuszewska B, Świerczewska M, Sterzyńska K, Nowicki M, Januchowski R
International journal of molecular sciences 2022 Mar 11;23(6)
International journal of molecular sciences 2022 Mar 11;23(6)
Endoplasmic reticulum-to-Golgi trafficking of procollagen III via conventional vesicular and tubular carriers.
Hirata Y, Matsui Y, Wada I, Hosokawa N
Molecular biology of the cell 2022 Mar 1;33(3):ar21
Molecular biology of the cell 2022 Mar 1;33(3):ar21
Protection of CAPE-pNO(2) Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Wan Q, Zhang L, Zhou Q, Han Y, Li Z, Li B
Inflammation 2022 Jun;45(3):1039-1058
Inflammation 2022 Jun;45(3):1039-1058
Overexpression of G Protein-Coupled Receptor 40 Protects Obesity-Induced Cardiomyopathy Through the SIRT1/LKB1/AMPK Pathway.
Li SN, Yu YL, Wang BY, Qiao SY, Hu MM, Wang H, Fu CN, Dong B
Human gene therapy 2022 Jun;33(11-12):598-613
Human gene therapy 2022 Jun;33(11-12):598-613
A myogenic niche with a proper mechanical stress environment improves abdominal wall muscle repair by modulating immunity and preventing fibrosis.
Wang S, Yan H, Fang B, Gu C, Guo J, Qiu P, Song N, Xu W, Zhang J, Lin X, Fang X
Biomaterials 2022 Jun;285:121519
Biomaterials 2022 Jun;285:121519
Suppression of the Inhibitory Effect of circ_0036176-Translated Myo9a-208 on Cardiac Fibroblast Proliferation by miR-218-5p.
Guo J, Chen LW, Huang ZQ, Guo JS, Li H, Shan Y, Chen ZR, Yan YM, Zhu JN, Guo HM, Fang XH, Shan ZX
Journal of cardiovascular translational research 2022 Jun;15(3):548-559
Journal of cardiovascular translational research 2022 Jun;15(3):548-559
TGF-β1 mediates pathologic changes of secondary lymphedema by promoting fibrosis and inflammation.
Baik JE, Park HJ, Kataru RP, Savetsky IL, Ly CL, Shin J, Encarnacion EM, Cavali MR, Klang MG, Riedel E, Coriddi M, Dayan JH, Mehrara BJ
Clinical and translational medicine 2022 Jun;12(6):e758
Clinical and translational medicine 2022 Jun;12(6):e758
Guanxin V alleviates acute myocardial infarction by restraining oxidative stress damage, apoptosis, and fibrosis through the TGF-β1 signalling pathway.
Liang B, Zhang XX, Li R, Zhu YC, Tian XJ, Gu N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154077
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154077
The Role of Verteporfin in Prevention of Periprosthetic Capsular Fibrosis: An Experimental Study.
Yi Z, Zeng J, Chen Z, Chen L, Lu HB, Zhang Q, Yang X, Qi Z
Aesthetic surgery journal 2022 Jun 20;42(7):820-829
Aesthetic surgery journal 2022 Jun 20;42(7):820-829
Estrogen deficiency aggravates fluorine ion-induced renal fibrosis via the TGF-β1/Smad signaling pathway in rats.
Liu S, Zhao J, Tian WS, Wang JC, Wang HW, Zhou BH
Toxicology letters 2022 Jun 1;362:26-37
Toxicology letters 2022 Jun 1;362:26-37
KGF-2 Regulates STAP-2-Mediated Signal Transducer and Activator of Transcription 3 Signaling and Reduces Skin Scar Formation.
Zhou Q, Gong J, Bi J, Yang X, Zhang L, Lu C, Li L, Chen M, Cai J, Yang R, Li X, Li Z, Wang X
The Journal of investigative dermatology 2022 Jul;142(7):2003-2013.e5
The Journal of investigative dermatology 2022 Jul;142(7):2003-2013.e5
COX-2/sEH Dual Inhibitor Alleviates Hepatocyte Senescence in NAFLD Mice by Restoring Autophagy through Sirt1/PI3K/AKT/mTOR.
Zhang CY, Tan XH, Yang HH, Jin L, Hong JR, Zhou Y, Huang XT
International journal of molecular sciences 2022 Jul 27;23(15)
International journal of molecular sciences 2022 Jul 27;23(15)
Revealing the mechanism of Jiegeng decoction attenuates bleomycin-induced pulmonary fibrosis via PI3K/Akt signaling pathway based on lipidomics and transcriptomics.
Xu Y, Wang X, Han D, Wang J, Luo Z, Jin T, Shi C, Zhou X, Lin L, Shan J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154207
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154207
Overexpressed COL3A1 has prognostic value in human esophageal squamous cell carcinoma and promotes the aggressiveness of esophageal squamous cell carcinoma by activating the NF-κB pathway.
Zhou J, Yang Y, Zhang H, Luan S, Xiao X, Li X, Fang P, Shang Q, Chen L, Zeng X, Yuan Y
Biochemical and biophysical research communications 2022 Jul 12;613:193-200
Biochemical and biophysical research communications 2022 Jul 12;613:193-200
Guanxin V protects against ventricular remodeling after acute myocardial infarction through the interaction of TGF-β1 and Vimentin.
Liang B, Zhang XX, Li R, Gu N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153866
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153866
Close Association between Altered Urine-Urothelium Barrier and Tertiary Lymphoid Structure Formation in the Renal Pelvis during Nephritis.
Ichii O, Hosotani M, Masum MA, Horino T, Otani Y, Namba T, Nakamura T, Hosny Ali EY, Kon Y
Journal of the American Society of Nephrology : JASN 2022 Jan;33(1):88-107
Journal of the American Society of Nephrology : JASN 2022 Jan;33(1):88-107
Morphological changes of macrophages and their potential contribution to tendon healing.
Yang QQ, Zhang L, Zhou YL, Tang JB
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 1):112145
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 1):112145
Long-term explant culture: an improved method for consistently harvesting homogeneous populations of keloid fibroblasts.
Li J, Zou Y, Wang S, Guo S, Huang Z, Huo R
Bioengineered 2022 Jan;13(1):1565-1574
Bioengineered 2022 Jan;13(1):1565-1574
Endothelial cell metabolic memory causes cardiovascular dysfunction in diabetes.
Yao Y, Song Q, Hu C, Da X, Yu Y, He Z, Xu C, Chen Q, Wang QK
Cardiovascular research 2022 Jan 7;118(1):196-211
Cardiovascular research 2022 Jan 7;118(1):196-211
ZC3H4 promotes pulmonary fibrosis via an ER stress-related positive feedback loop.
Ghafoor H, Chu H, Huang J, Chen M, Wang S, Wang J, Chao J
Toxicology and applied pharmacology 2022 Jan 15;435:115856
Toxicology and applied pharmacology 2022 Jan 15;435:115856
The effect of Q-switched 1064-nm dymium-doped yttrium aluminum garnet laser on the skin barrier and collagen synthesis through miR-24-3p.
Yang Z, Duan X, Wang X, Li D, Xu Q, Xiang S, Guo B, He L
Lasers in medical science 2022 Feb;37(1):205-214
Lasers in medical science 2022 Feb;37(1):205-214
Mitigation of portal fibrosis and cholestatic liver disease in ANKS6-deficient livers by macrophage depletion.
Airik M, McCourt B, Ozturk TT, Huynh AB, Zhang X, Tometich JT, Topaloglu R, Ozen H, Orhan D, Nejak-Bowen K, Monga SP, Hand TW, Ozaltin F, Airik R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22157
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22157
Fully Reduced HMGB1-Containing Peptide-Based Polyurethane Scaffold with Minimal Functional Unit of Skin (MFUS) Enhances Large and Deep Wounded Skin Healing.
Chang P, Li S, Sun Q, Guo K, Wang H, Li S, Zhang L, Xie Y, Zheng X, Liu Y
Macromolecular bioscience 2022 Feb;22(2):e2100403
Macromolecular bioscience 2022 Feb;22(2):e2100403
Uncaria Rhynchophylla attenuates angiotensin Ⅱ-induced myocardial fibrosis via suppression of the RhoA/ROCK1 pathway.
Xie L, Wang T, Lin S, Lu Z, Wang Y, Shen Z, Cheng Y, Shen A, Peng J, Chu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Feb;146:112607
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Feb;146:112607
QiShenYiQi pill for myocardial collagen metabolism and apoptosis in rats of autoimmune cardiomyopathy.
Lv S, Zhang W, Yuan P, Lu C, Dong J, Zhang J
Pharmaceutical biology 2022 Dec;60(1):722-728
Pharmaceutical biology 2022 Dec;60(1):722-728
Acacetin alleviates myocardial ischaemia/reperfusion injury by inhibiting oxidative stress and apoptosis via the Nrf-2/HO-1 pathway.
Wu C, Chen RL, Wang Y, Wu WY, Li G
Pharmaceutical biology 2022 Dec;60(1):553-561
Pharmaceutical biology 2022 Dec;60(1):553-561
Targeting the Akt/PI3K/mTOR signaling pathway for complete eradication of keloid disease by sunitinib.
Chen Y, Chen C, Fang J, Su K, Yuan Q, Hou H, Xin H, Sun J, Huang C, Li S, Yuan Z, Luo S
Apoptosis : an international journal on programmed cell death 2022 Dec;27(11-12):812-824
Apoptosis : an international journal on programmed cell death 2022 Dec;27(11-12):812-824
Activation of primary hepatic stellate cells and liver fibrosis induced by targeting TGF-β1/Smad signaling in schistosomiasis in mice.
Huang P, Ma H, Cao Y, Zhan T, Zhang T, Wang X, Zhang Y, Xu J, Xia C
Parasites & vectors 2022 Dec 6;15(1):456
Parasites & vectors 2022 Dec 6;15(1):456
Pinocembrin alleviates the susceptibility to atrial fibrillation in isoproterenol-induced rats.
Liu Z, Chen X, Ye T, Wan W, Yu Y, Zhang C, Yang B
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 1):33-40
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 1):33-40
Metformin Improves Burn Wound Healing by Modulating Microenvironmental Fibroblasts and Macrophages.
Shi L, Jiang Z, Li J, Lin H, Xu B, Liao X, Fu Z, Ao H, Guo G, Liu M
Cells 2022 Dec 16;11(24)
Cells 2022 Dec 16;11(24)
Spatio-Temporal Changes of Extracellular Matrix (ECM) Stiffness in the Development of the Leech Hirudo verbana.
Pulze L, Baranzini N, Congiu T, Acquati F, Grimaldi A
International journal of molecular sciences 2022 Dec 15;23(24)
International journal of molecular sciences 2022 Dec 15;23(24)
C/EBP-β contributes to pig endometrial LE receptivity by targeting cell remodeling genes during implantation.
Sun Y, Yang Y, Jiang Z, Wang F, Han K, Hong L, Cao J, Yu M
Reproduction (Cambridge, England) 2022 Dec 1;164(6):269-281
Reproduction (Cambridge, England) 2022 Dec 1;164(6):269-281
AGEs-RAGE axis mediates myocardial fibrosis via activation of cardiac fibroblasts induced by autophagy in heart failure.
Liang B, Zhou Z, Yang Z, Liu J, Zhang L, He J, Li H, Huang Y, Yang Q, Xian S, Wang L
Experimental physiology 2022 Aug;107(8):879-891
Experimental physiology 2022 Aug;107(8):879-891
Lidocaine Inhibited Tendon Cell Proliferation and Extracellular Matrix Production by Down Regulation of Cyclin A, CDK2, Type I and Type III Collagen Expression.
Chen YC, Chang HN, Pang JS, Lin LP, Chen JM, Yu TY, Tsai WC
International journal of molecular sciences 2022 Aug 7;23(15)
International journal of molecular sciences 2022 Aug 7;23(15)
The compound losartan cream inhibits scar formation via TGF-β/Smad pathway.
Zhao WY, Zhang LY, Wang ZC, Fang QQ, Wang XF, Du YZ, Shi BH, Lou D, Xuan GD, Tan WQ
Scientific reports 2022 Aug 22;12(1):14327
Scientific reports 2022 Aug 22;12(1):14327
The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.
Wang G, Duan J, Pu G, Ye C, Li Y, Xiu W, Xu J, Liu B, Zhu Y, Wang C
Biochimica et biophysica acta. Molecular basis of disease 2022 Aug 1;1868(8):166413
Biochimica et biophysica acta. Molecular basis of disease 2022 Aug 1;1868(8):166413
Immunohistochemical expression of osteopontin and collagens in choroid plexus of human brains.
Wakamatsu K, Chiba Y, Murakami R, Matsumoto K, Miyai Y, Kawauchi M, Yanase K, Uemura N, Ueno M
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Apr;42(2):117-125
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Apr;42(2):117-125
Botox-A improve the thyroid-associated ophthalmopathy (TAO) orbital fibroblast activation through inhibiting the TGF-β/Smad signaling.
Qi X, Luo B, Deng M, Cao J, Hou S, Xie Z, Tong B, Xiong W
Experimental eye research 2022 Apr;217:108971
Experimental eye research 2022 Apr;217:108971
Suppression of LMCD1 ameliorates renal fibrosis by blocking the activation of ERK pathway.
Yu R, Tian M, He P, Chen J, Zhao Z, Zhang Y, Zhang B
Biochimica et biophysica acta. Molecular cell research 2022 Apr;1869(4):119200
Biochimica et biophysica acta. Molecular cell research 2022 Apr;1869(4):119200
Exosomes from human adipose-derived mesenchymal stem cells inhibit production of extracellular matrix in keloid fibroblasts via downregulating transforming growth factor-β2 and Notch-1 expression.
Li J, Li Z, Wang S, Bi J, Huo R
Bioengineered 2022 Apr;13(4):8515-8525
Bioengineered 2022 Apr;13(4):8515-8525
Isoandrographolide inhibits NLRP3 inflammasome activation and attenuates silicosis in mice.
Song Z, Wang L, Cao Y, Liu Z, Zhang M, Zhang Z, Jiang S, Fan R, Hao T, Yang R, Wang B, Guan Z, Zhu L, Liu Z, Zhang S, Zhao L, Xu Z, Xu H, Dai G
International immunopharmacology 2022 Apr;105:108539
International immunopharmacology 2022 Apr;105:108539
A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon.
Zhao Y, Xue P, Lin G, Tong M, Yang J, Zhang Y, Ran K, Zhuge D, Yao Q, Xu H
Acta biomaterialia 2022 Apr 15;143:233-252
Acta biomaterialia 2022 Apr 15;143:233-252
Canine Mesenchymal Stromal Cell-Mediated Bone Regeneration is Enhanced in the Presence of Sub-Therapeutic Concentrations of BMP-2 in a Murine Calvarial Defect Model.
Dobson LK, Zeitouni S, McNeill EP, Bearden RN, Gregory CA, Saunders WB
Frontiers in bioengineering and biotechnology 2021;9:764703
Frontiers in bioengineering and biotechnology 2021;9:764703
Mesenchymal Stem Cells With Cancer-Associated Fibroblast-Like Phenotype Stimulate SDF-1/CXCR4 Axis to Enhance the Growth and Invasion of B-Cell Acute Lymphoblastic Leukemia Cells Through Cell-to-Cell Communication.
Pan C, Fang Q, Liu P, Ma D, Cao S, Zhang L, Chen Q, Hu T, Wang J
Frontiers in cell and developmental biology 2021;9:708513
Frontiers in cell and developmental biology 2021;9:708513
Epicardium-Derived Tbx18(+) CDCs Transplantation Improve Heart Function in Infarcted Mice.
Guo Z, Geng M, Qin L, Hao B, Liao S
Frontiers in cardiovascular medicine 2021;8:744353
Frontiers in cardiovascular medicine 2021;8:744353
Therapeutic Effects of an Inhibitor of Thioredoxin Reductase on Liver Fibrosis by Inhibiting the Transforming Growth Factor-β1/Smads Pathway.
Jiao W, Bai M, Yin H, Liu J, Sun J, Su X, Zeng H, Wen J
Frontiers in molecular biosciences 2021;8:690170
Frontiers in molecular biosciences 2021;8:690170
Estrogen Protects Vasomotor Functions in Rats During Catecholamine Stress.
Zhang L, Li C, Yang L, Adzika GK, Machuki JO, Shi M, Sun Q, Sun H
Frontiers in cardiovascular medicine 2021;8:679240
Frontiers in cardiovascular medicine 2021;8:679240
Early Passive Leg Movement Prevents Against the Development of Heart Failure With Preserved Ejection Fraction in Rats.
Liu J, Ji XX, Fu Y, Zhang WC, Ji HF, Liu JW, Cheng XS, Dong YF
Frontiers in cardiovascular medicine 2021;8:655009
Frontiers in cardiovascular medicine 2021;8:655009
PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell.
Li J, Wang C, Wang W, Liu L, Zhang Q, Zhang J, Wang B, Wang S, Hou L, Gao C, Yu X, Sun L
Frontiers in cardiovascular medicine 2021;8:624796
Frontiers in cardiovascular medicine 2021;8:624796
Exosomes Containing LINC00636 Inhibit MAPK1 through the miR-450a-2-3p Overexpression in Human Pericardial Fluid and Improve Cardiac Fibrosis in Patients with Atrial Fibrillation.
Liu L, Luo F, Lei K
Mediators of inflammation 2021;2021:9960241
Mediators of inflammation 2021;2021:9960241
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Zhang M, Luo C, Lin D, Cui K, Chen Z, Liu J
Oxidative medicine and cellular longevity 2021;2021:8877540
Oxidative medicine and cellular longevity 2021;2021:8877540
FTZ Ameliorates Diabetic Cardiomyopathy by Inhibiting Inflammation and Cardiac Fibrosis in the Streptozotocin-Induced Model.
Wang L, Wu H, Deng Y, Zhang S, Wei Q, Yang Q, Piao S, Bei W, Rong X, Guo J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5582567
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5582567
CircRNA FAT1 Regulates Osteoblastic Differentiation of Periodontal Ligament Stem Cells via miR-4781-3p/SMAD5 Pathway.
Ye Y, Ke Y, Liu L, Xiao T, Yu J
Stem cells international 2021;2021:5177488
Stem cells international 2021;2021:5177488
The Preventive Effect of Decorin on Epidural Fibrosis and Epidural Adhesions After Laminectomy.
Ding Q, Wei Q, Sheng G, Wang S, Jing S, Ma T, Zhang R, Wang T, Li W, Tang X, Wu H, Liu C
Frontiers in pharmacology 2021;12:774316
Frontiers in pharmacology 2021;12:774316
Ginsenoside Rb1 Ameliorates Diabetic Arterial Stiffening via AMPK Pathway.
Zhang X, Wang L, Guo R, Xiao J, Liu X, Dong M, Luan X, Ji X, Lu H
Frontiers in pharmacology 2021;12:753881
Frontiers in pharmacology 2021;12:753881
Follistatin Attenuates Myocardial Fibrosis in Diabetic Cardiomyopathy via the TGF-β-Smad3 Pathway.
Wang Y, Yu K, Zhao C, Zhou L, Cheng J, Wang DW, Zhao C
Frontiers in pharmacology 2021;12:683335
Frontiers in pharmacology 2021;12:683335
LncRNA Nuclear-Enriched Abundant Transcript 1 Regulates Atrial Fibrosis via the miR-320/NPAS2 Axis in Atrial Fibrillation.
Dai H, Zhao N, Liu H, Zheng Y, Zhao L
Frontiers in pharmacology 2021;12:647124
Frontiers in pharmacology 2021;12:647124
Conditioned medium from adipose-derived stem cells attenuates ischemia/reperfusion-induced cardiac injury through the microRNA-221/222/PUMA/ETS-1 pathway.
Lee TL, Lai TC, Lin SR, Lin SW, Chen YC, Pu CM, Lee IT, Tsai JS, Lee CW, Chen YL
Theranostics 2021;11(7):3131-3149
Theranostics 2021;11(7):3131-3149
Elevated IgE promotes cardiac fibrosis by suppressing miR-486a-5p.
Zhao H, Yang H, Geng C, Chen Y, Tang Y, Li Z, Pang J, Shu T, Nie Y, Liu Y, Jia K, Wang J
Theranostics 2021;11(15):7600-7615
Theranostics 2021;11(15):7600-7615
Identifying miRNA modules associated with progression of keloids through weighted gene co-expression network analysis and experimental validation in vitro.
Lv W, Ren Y, Wu M, Luo X, Yu J, Zhang Q, Wu Y
Burns : journal of the International Society for Burn Injuries 2021 Sep;47(6):1359-1372
Burns : journal of the International Society for Burn Injuries 2021 Sep;47(6):1359-1372
IGF-1-Expressing Placenta-Derived Mesenchymal Stem Cells Promote Scalding Wound Healing.
Cheng S, Lv R, Xu J, Hirman AR, Du L
The Journal of surgical research 2021 Sep;265:100-113
The Journal of surgical research 2021 Sep;265:100-113
Hydrogen gas inhalation ameliorates cardiac remodelling and fibrosis by regulating NLRP3 inflammasome in myocardial infarction rats.
Nie C, Zou R, Pan S, A R, Gao Y, Yang H, Bai J, Xi S, Wang X, Hong X, Yang W
Journal of cellular and molecular medicine 2021 Sep;25(18):8997-9010
Journal of cellular and molecular medicine 2021 Sep;25(18):8997-9010
Effect of different exercise training intensities on age-related cardiac damage in male mice.
Pei Z, Yang C, Guo Y, Dong M, Wang F
Aging 2021 Sep 14;13(17):21700-21711
Aging 2021 Sep 14;13(17):21700-21711
Changes in aortic collagen in β-aminopropionitrile-induced acute aortic dissection.
Zhou H, Ren Y, Xiao J, He J, Zhang Y, Qiu Z, Huang Q, Hu Y, Chen L
Annals of translational medicine 2021 Oct;9(20):1574
Annals of translational medicine 2021 Oct;9(20):1574
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Sun Y, Zhang L, Lu B, Wen J, Wang M, Zhang S, Li Q, Shu F, Lu F, Liu N, Peng S, Zhao Y, Dong S, Lu F, Zhang W, Wang Y
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Ghrelin ameliorates cardiac fibrosis after myocardial infarction by regulating the Nrf2/NADPH/ROS pathway.
Wang Q, Liu AD, Li TS, Tang Q, Wang XC, Chen XB
Peptides 2021 Oct;144:170613
Peptides 2021 Oct;144:170613
Tryptophan catabolism is dysregulated in leiomyomas.
Chuang TD, Quintanilla D, Boos D, Khorram O
Fertility and sterility 2021 Oct;116(4):1160-1171
Fertility and sterility 2021 Oct;116(4):1160-1171
Mesenchymal Stem Cell-Derived Exosomes Ameliorate Dermal Fibrosis in a Murine Model of Bleomycin-Induced Scleroderma.
Li M, Zhang HP, Wang XY, Chen ZG, Lin XF, Zhu W
Stem cells and development 2021 Oct 1;30(19):981-990
Stem cells and development 2021 Oct 1;30(19):981-990
Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway.
Lu ML, Wang J, Sun Y, Li C, Sun TR, Hou XW, Wang HX
Journal of ginseng research 2021 Nov;45(6):683-694
Journal of ginseng research 2021 Nov;45(6):683-694
Blood glucose control contributes to protein stability of Ski-related novel protein N in a rat model of diabetes.
Liang L, Li S, Liu H, Mao Y, Liu L, Zhang X, Peng W, Xiao Y, Zhang F, Shi M, Wang Y, Guo B
Experimental and therapeutic medicine 2021 Nov;22(5):1341
Experimental and therapeutic medicine 2021 Nov;22(5):1341
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Xu Y, Peng W, Han D, Feng F, Wang Z, Gu C, Zhou X, Wu Q
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Exosomal MicroRNA-21 Promotes Keloid Fibroblast Proliferation and Collagen Production by Inhibiting Smad7.
Li Q, Fang L, Chen J, Zhou S, Zhou K, Cheng F, Cen Y, Qing Y, Wu J
Journal of burn care & research : official publication of the American Burn Association 2021 Nov 24;42(6):1266-1274
Journal of burn care & research : official publication of the American Burn Association 2021 Nov 24;42(6):1266-1274
Exercise Training Alleviates Cardiac Fibrosis through Increasing Fibroblast Growth Factor 21 and Regulating TGF-β1-Smad2/3-MMP2/9 Signaling in Mice with Myocardial Infarction.
Ma Y, Kuang Y, Bo W, Liang Q, Zhu W, Cai M, Tian Z
International journal of molecular sciences 2021 Nov 15;22(22)
International journal of molecular sciences 2021 Nov 15;22(22)
Connective tissue growth factor promotes retinal pigment epithelium mesenchymal transition via the PI3K/AKT signaling pathway.
Wang Y, Chang T, Wu T, Ye W, Wang Y, Dou G, Du H, Hui Y, Guo C
Molecular medicine reports 2021 May;23(5)
Molecular medicine reports 2021 May;23(5)
Qingda granule attenuates cardiac fibrosis via suppression of the TGF-β1/Smad2/3 signaling pathway in vitro and in vivo.
Chen X, Long L, Cheng Y, Chu J, Shen Z, Liu L, Li J, Xie Q, Liu H, Wu M, Chen Y, Peng J, Shen A
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111318
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111318
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
Long F, Yang D, Wang J, Wang Q, Ni T, Wei G, Zhu Y, Liu X
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
Controlled release of KGF-2 for regulation of wound healing by KGF-2 complexed with "lotus seedpod surface-like" porous microspheres.
Pan H, Shi C, Yang R, Xi G, Lu C, Yang X, Chen J, Wang X, Chen L, Pan J
Journal of materials chemistry. B 2021 May 19;9(19):4039-4049
Journal of materials chemistry. B 2021 May 19;9(19):4039-4049
Celecoxib ameliorates liver cirrhosis via reducing inflammation and oxidative stress along spleen-liver axis in rats.
Tang S, Huang Z, Jiang J, Gao J, Zhao C, Tai Y, Ma X, Zhang L, Ye Y, Gan C, Su W, Jia X, Liu R, Wu H, Tang C
Life sciences 2021 May 1;272:119203
Life sciences 2021 May 1;272:119203
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.
Zhao B, Li S, Guo Z, Chen Z, Zhang X, Xu C, Chen J, Wei C
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):370-380
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):370-380
Umbilical cord-derived mesenchymal stem cells exert anti-fibrotic action on hypertrophic scar-derived fibroblasts in co-culture by inhibiting the activation of the TGF β1/Smad3 pathway.
Meng X, Gao X, Chen X, Yu J
Experimental and therapeutic medicine 2021 Mar;21(3):210
Experimental and therapeutic medicine 2021 Mar;21(3):210
SAIL: a new conserved anti-fibrotic lncRNA in the heart.
Luo S, Zhang M, Wu H, Ding X, Li D, Dong X, Hu X, Su S, Shang W, Wu J, Xiao H, Yang W, Zhang Q, Zhang J, Lu Y, Pan Z
Basic research in cardiology 2021 Mar 6;116(1):15
Basic research in cardiology 2021 Mar 6;116(1):15
Deletion of fibroblast activation protein provides atheroprotection.
Stein S, Weber J, Nusser-Stein S, Pahla J, Zhang HE, Mohammed SA, Oppi S, Gaul DS, Paneni F, Tailleux A, Staels B, von Meyenn F, Ruschitzka F, Gorrell MD, Lüscher TF, Matter CM
Cardiovascular research 2021 Mar 21;117(4):1060-1069
Cardiovascular research 2021 Mar 21;117(4):1060-1069
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Han D, Xu Y, Peng WP, Feng F, Wang Z, Gu C, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Troxerutin Improves Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice.
Wang X, Gao Y, Wang L, Yang D, Bu W, Gou L, Huang J, Duan X, Pan Y, Cao S, Gao Z, Cheng C, Feng Z, Xie J, Yao R
Journal of agricultural and food chemistry 2021 Mar 10;69(9):2729-2744
Journal of agricultural and food chemistry 2021 Mar 10;69(9):2729-2744
Regulation of connective tissue growth factor expression by miR-133b for the treatment of renal interstitial fibrosis in aged mice with unilateral ureteral obstruction.
Cao D, Wang Y, Zhang Y, Zhang Y, Huang Q, Yin Z, Cai G, Chen X, Sun X
Stem cell research & therapy 2021 Mar 10;12(1):171
Stem cell research & therapy 2021 Mar 10;12(1):171
Microsphere-Embedded Hydrogel Sustained-Release System to Inhibit Postoperative Epidural Fibrosis.
Wang S, Shi K, Lu J, Sun W, Han Q, Che L, Zhang D
ACS applied bio materials 2021 Jun 21;4(6):5122-5131
ACS applied bio materials 2021 Jun 21;4(6):5122-5131
Vincristine attenuates cardiac fibrosis through the inhibition of NLRP3 inflammasome activation.
Ge C, Cheng Y, Fan Y, He Y
Clinical science (London, England : 1979) 2021 Jun 11;135(11):1409-1426
Clinical science (London, England : 1979) 2021 Jun 11;135(11):1409-1426
The magnitude of airway remodeling is not altered by distinct allergic inflammatory responses in BALB/c versus C57BL/6 mice but matrix composition differs.
Parkinson JE, Pearson S, Rückerl D, Allen JE, Sutherland TE
Immunology and cell biology 2021 Jul;99(6):640-655
Immunology and cell biology 2021 Jul;99(6):640-655
Periplocymarin protects against myocardial fibrosis induced by β-adrenergic activation in mice.
Yun W, Qian L, Yuan R, Xu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111562
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111562
Huoxin Pill inhibits isoproterenol-induced transdifferentiation and collagen synthesis in cardiac fibroblasts through the TGF-β/Smads pathway.
Peng M, Yang M, Lu Y, Lin S, Gao H, Xie L, Huang B, Chen D, Shen A, Shen Z, Peng J, Chu J
Journal of ethnopharmacology 2021 Jul 15;275:114061
Journal of ethnopharmacology 2021 Jul 15;275:114061
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Chen C, Gu J, Wang J, Wu Y, Yang A, Chen T, Zhou T, Liu Z
International immunopharmacology 2021 Jan;90:107206
International immunopharmacology 2021 Jan;90:107206
Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway.
Lv W, Wu M, Ren Y, Luo X, Hu W, Zhang Q, Wu Y
Molecular medicine reports 2021 Jan;23(1)
Molecular medicine reports 2021 Jan;23(1)
Functional role of the long noncoding RNA X-inactive specific transcript in leiomyoma pathogenesis.
Chuang TD, Rehan A, Khorram O
Fertility and sterility 2021 Jan;115(1):238-247
Fertility and sterility 2021 Jan;115(1):238-247
A lncRNA Gpr137b-ps/miR-200a-3p/CXCL14 axis modulates hepatic stellate cell (HSC) activation.
Liao J, Zhang Z, Yuan Q, Liu Q, Kuang J, Fang Y, Hu X
Toxicology letters 2021 Jan 1;336:21-31
Toxicology letters 2021 Jan 1;336:21-31
Pathological Alternations of Mediastinal Fat-Associated Lymphoid Cluster and Lung in a Streptozotocin-Induced Diabetic Mouse Model.
Elewa YHA, Ichii O, Nakamura T, Kon Y
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 2021 Feb;27(1):187-200
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 2021 Feb;27(1):187-200
Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice.
Liu YS, Yang Q, Li S, Luo L, Liu HY, Li XY, Gao ZN
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Tenogenic adipose-derived stem cell sheets with nanoyarn scaffolds for tendon regeneration.
Chen S, Wang J, Chen Y, Mo X, Fan C
Materials science & engineering. C, Materials for biological applications 2021 Feb;119:111506
Materials science & engineering. C, Materials for biological applications 2021 Feb;119:111506
Cancer-Associated Fibroblast Subgroups Showing Differential Promoting Effect on HNSCC Progression.
Kang SH, Oh SY, Lee HJ, Kwon TG, Kim JW, Lee ST, Choi SY, Hong SH
Cancers 2021 Feb 6;13(4)
Cancers 2021 Feb 6;13(4)
The role of CDX2 in renal tubular lesions during diabetic kidney disease.
Liu H, Yan R, Liang L, Zhang H, Xiang J, Liu L, Zhang X, Mao Y, Peng W, Xiao Y, Zhang F, Zhou Y, Shi M, Wang Y, Guo B
Aging 2021 Feb 17;13(5):6782-6803
Aging 2021 Feb 17;13(5):6782-6803
Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats.
An R, Wang X, Yang L, Zhang J, Wang N, Xu F, Hou Y, Zhang H, Zhang L
Toxicology 2021 Feb 15;449:152665
Toxicology 2021 Feb 15;449:152665
Leonurine Attenuates Myocardial Fibrosis Through Upregulation of miR-29a-3p in Mice Post-myocardial Infarction.
Wang R, Peng L, Lv D, Shang F, Yan J, Li G, Li D, Ouyang J, Yang J
Journal of cardiovascular pharmacology 2021 Feb 1;77(2):189-199
Journal of cardiovascular pharmacology 2021 Feb 1;77(2):189-199
Ginsenoside Rb1 attenuates age-associated vascular impairment by modulating the Gas6 pathway.
Ke S, Wu L, Wang M, Liu D, Shi G, Zhu J, Qian X
Pharmaceutical biology 2021 Dec;59(1):1369-1377
Pharmaceutical biology 2021 Dec;59(1):1369-1377
Epigallocatechin gallate (EGCG) attenuates myocardial hypertrophy and fibrosis induced by transverse aortic constriction via inhibiting the Akt/mTOR pathway.
Cui Y, Wang Y, Liu G
Pharmaceutical biology 2021 Dec;59(1):1305-1313
Pharmaceutical biology 2021 Dec;59(1):1305-1313
Huoxue Qianyang Qutan recipe attenuates cardiac fibrosis by inhibiting the NLRP3 inflammasome signalling pathway in obese hypertensive rats.
Lu B, Xie J, Fu D, Chen X, Zhao M, Gui M, Yao L, Zhou X, Li J
Pharmaceutical biology 2021 Dec;59(1):1045-1057
Pharmaceutical biology 2021 Dec;59(1):1045-1057
Huoxin pill prevents acute myocardial ischaemia injury via inhibition of Wnt/β-catenin signaling.
Wang Q, Ma E, Wo D, Chen J, He J, Peng J, Zhu W, Ren DN
Journal of cellular and molecular medicine 2021 Dec;25(24):11053-11062
Journal of cellular and molecular medicine 2021 Dec;25(24):11053-11062
Radiation‑induced dysfunction of energy metabolism in the heart results in the fibrosis of cardiac tissues.
Xu P, Yi Y, Luo Y, Liu Z, Xu Y, Cai J, Zeng Z, Liu A
Molecular medicine reports 2021 Dec;24(6)
Molecular medicine reports 2021 Dec;24(6)
Dickkopf 3: a Novel Target Gene of miR-25-3p in Promoting Fibrosis-Related Gene Expression in Myocardial Fibrosis.
Zeng N, Wen YH, Pan R, Yang J, Yan YM, Zhao AZ, Zhu JN, Fang XH, Shan ZX
Journal of cardiovascular translational research 2021 Dec;14(6):1051-1062
Journal of cardiovascular translational research 2021 Dec;14(6):1051-1062
M2 Macrophage-derived exosomal miR-501 contributes to pubococcygeal muscle regeneration.
Zhou M, Li B, Liu C, Hu M, Tang J, Min J, Cheng J, Hong L
International immunopharmacology 2021 Dec;101(Pt B):108223
International immunopharmacology 2021 Dec;101(Pt B):108223
Diverging targets mediate the pathological roleof miR-199a-5p and miR-199a-3p by promoting cardiac hypertrophy and fibrosis.
Zeng N, Huang YQ, Yan YM, Hu ZQ, Zhang Z, Feng JX, Guo JS, Zhu JN, Fu YH, Wang XP, Zhang MZ, Duan JZ, Zheng XL, Xu JD, Shan ZX
Molecular therapy. Nucleic acids 2021 Dec 3;26:1035-1050
Molecular therapy. Nucleic acids 2021 Dec 3;26:1035-1050
Effects of L-leucine on the properties of spray-dried swellable microparticles with wrinkled surfaces for inhalation therapy of pulmonary fibrosis.
Wang X, Wan W, Lu J, Quan G, Pan X, Liu P
International journal of pharmaceutics 2021 Dec 15;610:121223
International journal of pharmaceutics 2021 Dec 15;610:121223
Gsα deficiency facilitates cardiac remodeling via CREB/ Bmp10-mediated signaling.
Yin P, Li D, Zhao Q, Cai M, Wu Z, Shi Y, Su L
Cell death discovery 2021 Dec 14;7(1):391
Cell death discovery 2021 Dec 14;7(1):391
Citrus alkaline extracts prevent endoplasmic reticulum stress in type II alveolar epithelial cells to ameliorate pulmonary fibrosis via the ATF3/PINK1 pathway.
Wang Z, Feng F, He H, Wu Q, Gu C, Hrovat J, Peng W, Xu Y, Han D, Yang P, Zhou X, Li J, Shan J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Aug;89:153599
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Aug;89:153599
ER-anchored CRTH2 antagonizes collagen biosynthesis and organ fibrosis via binding LARP6.
Zuo S, Wang B, Liu J, Kong D, Cui H, Jia Y, Wang C, Xu X, Chen G, Wang Y, Yang L, Zhang K, Ai D, Du J, Shen Y, Yu Y
The EMBO journal 2021 Aug 16;40(16):e107403
The EMBO journal 2021 Aug 16;40(16):e107403
Zi Qi Decoction Alleviates Liver Fibrosis by Inhibiting the Toll-Like Receptor 4 (TLR4)-Related Nuclear Factor kappa b (NF-κB) and Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways.
Zhou J, Zhang X, Wan L, Yu J, Li T, Lu Z, Fang N, Sun L, Ye F
Medical science monitor : international medical journal of experimental and clinical research 2021 Apr 14;27:e929438
Medical science monitor : international medical journal of experimental and clinical research 2021 Apr 14;27:e929438
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
Cao Z, Cheng Y, Wang J, Liu Y, Yang R, Jiang W, Li H, Zhang X
Journal of experimental & clinical cancer research : CR 2021 Apr 1;40(1):118
Journal of experimental & clinical cancer research : CR 2021 Apr 1;40(1):118
Ginsenoside Rb1 Ameliorates Age-Related Myocardial Dysfunction by Regulating the NF-κB Signaling Pathway.
Ke SY, Liu DH, Wu L, Yu XG, Wang M, Shi GY, Wen RH, Zhou B, Hao BS, Liu Y, Zhu JM, Qian XX
The American journal of Chinese medicine 2020;48(6):1369-1383
The American journal of Chinese medicine 2020;48(6):1369-1383
Exposure to Air Pollution Exacerbates Inflammation in Rats with Preexisting COPD.
Wang J, Li Y, Zhao P, Tian Y, Liu X, He H, Jia R, Oliver BG, Li J
Mediators of inflammation 2020;2020:4260204
Mediators of inflammation 2020;2020:4260204
MicroRNA-21-3p Engineered Umbilical Cord Stem Cell-Derived Exosomes Inhibit Tendon Adhesion.
Yao Z, Li J, Wang X, Peng S, Ning J, Qian Y, Fan C
Journal of inflammation research 2020;13:303-316
Journal of inflammation research 2020;13:303-316
Dexmedetomidine Exerted Anti-arrhythmic Effects in Rat With Ischemic Cardiomyopathy via Upregulation of Connexin 43 and Reduction of Fibrosis and Inflammation.
Wu SJ, Lin ZH, Lin YZ, Rao ZH, Lin JF, Wu LP, Li L
Frontiers in physiology 2020;11:33
Frontiers in physiology 2020;11:33
Splenectomy enhances the Ly6C(low) phenotype in hepatic macrophages by activating the ERK1/2 pathway during liver fibrosis.
Zheng Z, Wang H, Li L, Zhang S, Zhang C, Zhang H, Ji F, Liu X, Zhu K, Kong G, Li Z
International immunopharmacology 2020 Sep;86:106762
International immunopharmacology 2020 Sep;86:106762
hUMSCs regulate the differentiation of ovarian stromal cells via TGF-β(1)/Smad3 signaling pathway to inhibit ovarian fibrosis to repair ovarian function in POI rats.
Cui L, Bao H, Liu Z, Man X, Liu H, Hou Y, Luo Q, Wang S, Fu Q, Zhang H
Stem cell research & therapy 2020 Sep 7;11(1):386
Stem cell research & therapy 2020 Sep 7;11(1):386
Mechanism underlying increased cardiac extracellular matrix deposition in perinatal nicotine-exposed offspring.
Chuang TD, Ansari A, Yu C, Sakurai R, Harb A, Liu J, Khorram O, Rehan VK
American journal of physiology. Heart and circulatory physiology 2020 Sep 1;319(3):H651-H660
American journal of physiology. Heart and circulatory physiology 2020 Sep 1;319(3):H651-H660
Polyunsaturated fatty acid supplement alleviates depression-incident cognitive dysfunction by protecting the cerebrovascular and glymphatic systems.
Liu X, Hao J, Yao E, Cao J, Zheng X, Yao D, Zhang C, Li J, Pan D, Luo X, Wang M, Wang W
Brain, behavior, and immunity 2020 Oct;89:357-370
Brain, behavior, and immunity 2020 Oct;89:357-370
Polystyrene microplastics cause cardiac fibrosis by activating Wnt/β-catenin signaling pathway and promoting cardiomyocyte apoptosis in rats.
Li Z, Zhu S, Liu Q, Wei J, Jin Y, Wang X, Zhang L
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt A):115025
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt A):115025
MSC-derived exosomes protect against oxidative stress-induced skin injury via adaptive regulation of the NRF2 defense system.
Wang T, Jian Z, Baskys A, Yang J, Li J, Guo H, Hei Y, Xian P, He Z, Li Z, Li N, Long Q
Biomaterials 2020 Oct;257:120264
Biomaterials 2020 Oct;257:120264
Endothelin receptors promote schistosomiasis-induced hepatic fibrosis via splenic B cells.
Kong H, He J, Guo S, Song Q, Xiang D, Tao R, Yu H, Chen G, Huang Z, Ning Q, Huang J
PLoS pathogens 2020 Oct;16(10):e1008947
PLoS pathogens 2020 Oct;16(10):e1008947
Citri Reticulatae Pericarpium protects against isoproterenol-induced chronic heart failure via activation of PPARγ.
Cheng H, Wu X, Ni G, Wang S, Peng W, Zhang H, Gao J, Li X
Annals of translational medicine 2020 Nov;8(21):1396
Annals of translational medicine 2020 Nov;8(21):1396
Construction and performance evaluation of Hep/silk-PLCL composite nanofiber small-caliber artificial blood vessel graft.
Kuang H, Wang Y, Shi Y, Yao W, He X, Liu X, Mo X, Lu S, Zhang P
Biomaterials 2020 Nov;259:120288
Biomaterials 2020 Nov;259:120288
The role of Hrd1 in ultraviolet (UV) radiation induced photoaging.
Jin Y, Cheng X, Huang X, Ding F, Lee SR, Wang F, Lu X, Su D, Chen B
Aging 2020 Nov 9;12(21):21273-21289
Aging 2020 Nov 9;12(21):21273-21289
KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats.
Yang X, Yang R, Chen M, Zhou Q, Zheng Y, Lu C, Bi J, Sun W, Huang T, Li L, Gong J, Li X, Hui Q, Wang X
BMJ open diabetes research & care 2020 May;8(1)
BMJ open diabetes research & care 2020 May;8(1)
G protein-coupled receptor kinase-2: A potential biomarker for early diabetic cardiomyopathy.
Lai S, Fu X, Yang S, Zhang S, Lin Q, Zhang M, Chen H
Journal of diabetes 2020 Mar;12(3):247-258
Journal of diabetes 2020 Mar;12(3):247-258
Kidney targeted delivery of asiatic acid using a FITC labeled renal tubular-targeting peptide modified PLGA-PEG system.
He J, Chen H, Zhou W, Chen M, Yao Y, Zhang Z, Tan N
International journal of pharmaceutics 2020 Jun 30;584:119455
International journal of pharmaceutics 2020 Jun 30;584:119455
Role of Interleukin-17 in Pathogenesis of Intestinal Fibrosis in Mice.
Li J, Liu L, Zhao Q, Chen M
Digestive diseases and sciences 2020 Jul;65(7):1971-1979
Digestive diseases and sciences 2020 Jul;65(7):1971-1979
Administration of a mixture of triterpenoids from yeyachun and phenolic acids from danshen ameliorates carbon tetrachloride-induced liver fibrosis in mice by the regulation of intestinal flora.
Tan Y, Li Y, Zhou F, Guo J, Wang T, Shi Y, Yang Y, Lu J, Pei G
Journal of pharmacological sciences 2020 Jul;143(3):165-175
Journal of pharmacological sciences 2020 Jul;143(3):165-175
Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression.
Su C, Wang Q, Luo H, Jiao W, Tang J, Li L, Tian L, Chen X, Liu B, Yu X, Li S, Guo S, Wang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110132
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110132
Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload.
Wang J, Deng B, Liu Q, Huang Y, Chen W, Li J, Zhou Z, Zhang L, Liang B, He J, Chen Z, Yan C, Yang Z, Xian S, Wang L
Cell death & disease 2020 Jul 24;11(7):574
Cell death & disease 2020 Jul 24;11(7):574
Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling.
Li J, Ma J, Tian Y, Zhao P, Liu X, Dong H, Zheng W, Feng S, Zhang L, Wu M, Zhu L, Liu S, Zhao D
Journal of ethnopharmacology 2020 Jul 15;257:112796
Journal of ethnopharmacology 2020 Jul 15;257:112796
Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.
Wang X, Lin L, Chai X, Wu Y, Li Y, Liu X
International journal of molecular medicine 2020 Jan;45(1):175-185
International journal of molecular medicine 2020 Jan;45(1):175-185
Psoralen attenuates bleomycin-induced pulmonary fibrosis in mice through inhibiting myofibroblast activation and collagen deposition.
Du MY, Duan JX, Zhang CY, Yang HH, Guan XX, Zhong WJ, Liu YZ, Li ZM, Cheng YR, Zhou Y, Guan CX
Cell biology international 2020 Jan;44(1):98-107
Cell biology international 2020 Jan;44(1):98-107
Tanshinone IIA attenuates silica-induced pulmonary fibrosis via inhibition of TGF-β1-Smad signaling pathway.
Feng F, Li N, Cheng P, Zhang H, Wang H, Wang Y, Wang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109586
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109586
Left Atrial Appendage Fibrosis and 3-Year Clinical Outcomes in Atrial Fibrillation After Endoscopic Ablation: A Histologic Analysis.
Ma N, Lu R, Zhao D, Jiang Z, Tang M, Bao C, Mei J
The Annals of thoracic surgery 2020 Jan;109(1):69-76
The Annals of thoracic surgery 2020 Jan;109(1):69-76
Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.
Fu S, Li Y, Wu Y, Yue Y, Yang D
The Journal of pharmacy and pharmacology 2020 Feb;72(2):227-235
The Journal of pharmacy and pharmacology 2020 Feb;72(2):227-235
MicroRNA-29a attenuates angiotensin-II induced-left ventricular remodeling by inhibiting collagen, TGF-β and SMAD2/3 expression.
Zhang SJ, Yun CJ, Liu J, Yao SY, Li Y, Wang M, Wang C, Bai YY, Xue H
Journal of geriatric cardiology : JGC 2020 Feb;17(2):96-104
Journal of geriatric cardiology : JGC 2020 Feb;17(2):96-104
β2-microglobulin as a biomarker of pulmonary fibrosis development in COPD patients.
Wu Z, Yan M, Zhang M, Wu N, Ma G, Wang B, Fan Y, Du X, Ding C, Liu Y
Aging 2020 Dec 21;13(1):1251-1263
Aging 2020 Dec 21;13(1):1251-1263
Atorvastatin attenuates TGF‑β1‑induced fibrogenesis by inhibiting Smad3 and MAPK signaling in human ventricular fibroblasts.
Du Y, Xiao H, Wan J, Wang X, Li T, Zheng S, Feng J, Ye Q, Li J, Li G, Fan Z
International journal of molecular medicine 2020 Aug;46(2):633-640
International journal of molecular medicine 2020 Aug;46(2):633-640
Sumoylation enhances the activity of the TGF-β/SMAD and HIF-1 signaling pathways in keloids.
Lin X, Wang Y, Jiang Y, Xu M, Pang Q, Sun J, Yu Y, Shen Z, Lei R, Xu J
Life sciences 2020 Aug 15;255:117859
Life sciences 2020 Aug 15;255:117859
Growth and Stem Cell Characteristics of Tendon-Derived Cells with Different Initial Seeding Densities: An In Vitro Study in Mouse Flexor Tendon Cells.
Wu YF, Chen C, Tang JB, Mao WF
Stem cells and development 2020 Aug 1;29(15):1016-1025
Stem cells and development 2020 Aug 1;29(15):1016-1025
LncRNA MIAT/miR-133a-3p axis regulates atrial fibrillation and atrial fibrillation-induced myocardial fibrosis.
Yao L, Zhou B, You L, Hu H, Xie R
Molecular biology reports 2020 Apr;47(4):2605-2617
Molecular biology reports 2020 Apr;47(4):2605-2617
Downregulation of miR-96 suppresses the profibrogenic functions of cardiac fibroblasts induced by angiotensin II and attenuates atrial fibrosis by upregulating KLF13.
Su L, Yao Y, Song W
Human cell 2020 Apr;33(2):337-346
Human cell 2020 Apr;33(2):337-346
COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence.
Zhang CY, Duan JX, Yang HH, Sun CC, Zhong WJ, Tao JH, Guan XX, Jiang HL, Hammock BD, Hwang SH, Zhou Y, Guan CX
The FEBS journal 2020 Apr;287(8):1666-1680
The FEBS journal 2020 Apr;287(8):1666-1680
Adipose‑derived mesenchymal stem cells ameliorate dibutyltin dichloride‑induced chronic pancreatitis by inhibiting the PI3K/AKT/mTOR signaling pathway.
Xu X, Yu H, Sun L, Zheng C, Shan Y, Zhou Z, Wang C, Chen B
Molecular medicine reports 2020 Apr;21(4):1833-1840
Molecular medicine reports 2020 Apr;21(4):1833-1840
Nrf2 in keratinocytes protects against skin fibrosis via regulating epidermal lesion and inflammatory response.
Wu R, Zhang H, Zhao M, Li J, Hu Y, Fu J, Pi J, Wang H, Xu Y
Biochemical pharmacology 2020 Apr;174:113846
Biochemical pharmacology 2020 Apr;174:113846
Blocking interleukin-6 trans-signaling protects against renal fibrosis by suppressing STAT3 activation.
Chen W, Yuan H, Cao W, Wang T, Chen W, Yu H, Fu Y, Jiang B, Zhou H, Guo H, Zhao X
Theranostics 2019;9(14):3980-3991
Theranostics 2019;9(14):3980-3991
Depletion of WNT10A Prevents Tumor Growth by Suppressing Microvessels and Collagen Expression.
Kumagai M, Guo X, Wang KY, Izumi H, Tsukamoto M, Nakashima T, Tasaki T, Kurose N, Uramoto H, Sasaguri Y, Kohno K, Yamada S
International journal of medical sciences 2019;16(3):416-423
International journal of medical sciences 2019;16(3):416-423
Presence and function of stress granules in atrial fibrillation.
Dong G, Liang F, Sun B, Wang C, Liu Y, Guan X, Yang B, Xiu C, Yang N, Liu F, Lu T, Han W
PloS one 2019;14(4):e0213769
PloS one 2019;14(4):e0213769
Stachydrine Ameliorates Cardiac Fibrosis Through Inhibition of Angiotensin II/Transformation Growth Factor β1 Fibrogenic Axis.
Liu X, Shan X, Chen H, Li Z, Zhao P, Zhang C, Guo W, Xu M, Lu R
Frontiers in pharmacology 2019;10:538
Frontiers in pharmacology 2019;10:538
The Smad3-miR-29b/miR-29c axis mediates the protective effect of macrophage migration inhibitory factor against cardiac fibrosis.
Liang JN, Zou X, Fang XH, Xu JD, Xiao Z, Zhu JN, Li H, Yang J, Zeng N, Yuan SJ, Pan R, Fu YH, Zhang M, Luo JF, Wang S, Shan ZX
Biochimica et biophysica acta. Molecular basis of disease 2019 Sep 1;1865(9):2441-2450
Biochimica et biophysica acta. Molecular basis of disease 2019 Sep 1;1865(9):2441-2450
Inhibition of Glutaminase 1 Attenuates Experimental Pulmonary Fibrosis.
Cui H, Xie N, Jiang D, Banerjee S, Ge J, Sanders YY, Liu G
American journal of respiratory cell and molecular biology 2019 Oct;61(4):492-500
American journal of respiratory cell and molecular biology 2019 Oct;61(4):492-500
The effect of topical ramipril and losartan cream in inhibiting scar formation.
Zheng B, Fang QQ, Wang XF, Shi BH, Zhao WY, Chen CY, Zhang MX, Zhang LY, Hu YY, Shi P, Ma L, Tan WQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109394
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109394
SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition.
Liu ZH, Zhang Y, Wang X, Fan XF, Zhang Y, Li X, Gong YS, Han LP
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109227
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109227
Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection.
Chen TT, Peng S, Wang Y, Hu Y, Shen Y, Xu Y, Yin J, Liu C, Cao J
Biomolecules 2019 Oct 25;9(11)
Biomolecules 2019 Oct 25;9(11)
Blockade of lncRNA-ASLNCS5088-enriched exosome generation in M2 macrophages by GW4869 dampens the effect of M2 macrophages on orchestrating fibroblast activation.
Chen J, Zhou R, Liang Y, Fu X, Wang D, Wang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):12200-12212
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):12200-12212
Novel role of the clustered miR-23b-3p and miR-27b-3p in enhanced expression of fibrosis-associated genes by targeting TGFBR3 in atrial fibroblasts.
Yang Z, Xiao Z, Guo H, Fang X, Liang J, Zhu J, Yang J, Li H, Pan R, Yuan S, Dong W, Zheng XL, Wu S, Shan Z
Journal of cellular and molecular medicine 2019 May;23(5):3246-3256
Journal of cellular and molecular medicine 2019 May;23(5):3246-3256
Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.
Gao J, Guo Y, Chen Y, Zhou J, Liu Y, Su P
Gene 2019 May 20;697:11-18
Gene 2019 May 20;697:11-18
Concentrated Growth Factors Can Inhibit Photoaging Damage Induced by Ultraviolet A (UVA) on the Human Dermal Fibroblasts In Vitro.
Chen J, Jiao D, Zhang M, Zhong S, Zhang T, Ren X, Ren G
Medical science monitor : international medical journal of experimental and clinical research 2019 May 20;25:3739-3749
Medical science monitor : international medical journal of experimental and clinical research 2019 May 20;25:3739-3749
Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways.
Li R, Guo Y, Zhang Y, Zhang X, Zhu L, Yan T
International journal of molecular sciences 2019 Mar 4;20(5)
International journal of molecular sciences 2019 Mar 4;20(5)
Vascular smooth muscle cell-specific progerin expression in a mouse model of Hutchinson-Gilford progeria syndrome promotes arterial stiffness: Therapeutic effect of dietary nitrite.
Del Campo L, Sánchez-López A, Salaices M, von Kleeck RA, Expósito E, González-Gómez C, Cussó L, Guzmán-Martínez G, Ruiz-Cabello J, Desco M, Assoian RK, Briones AM, Andrés V
Aging cell 2019 Jun;18(3):e12936
Aging cell 2019 Jun;18(3):e12936
The emerging roles of a novel CCCH-type zinc finger protein, ZC3H4, in silica-induced epithelial to mesenchymal transition.
Jiang R, Zhou Z, Liao Y, Yang F, Cheng Y, Huang J, Wang J, Chen H, Zhu T, Chao J
Toxicology letters 2019 Jun 1;307:26-40
Toxicology letters 2019 Jun 1;307:26-40
Eliciting α7-nAChR exerts cardioprotective effects on ischemic cardiomyopathy via activation of AMPK signalling.
Lin ZH, Li YC, Wu SJ, Zheng C, Lin YZ, Lian H, Lin WQ, Lin JF
Journal of cellular and molecular medicine 2019 Jul;23(7):4746-4758
Journal of cellular and molecular medicine 2019 Jul;23(7):4746-4758
HBOA ameliorates CCl(4)-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways.
Sun X, Huang X, Zhu X, Liu L, Mo S, Wang H, Wei X, Lu S, Bai F, Wang D, Lin X, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108901
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108901
Nox1/4 dual inhibitor GKT137831 attenuates hypertensive cardiac remodelling associating with the inhibition of ADAM17-dependent proinflammatory cytokines-induced signalling pathways in the rats with abdominal artery constriction.
Zeng SY, Yang L, Yan QJ, Gao L, Lu HQ, Yan PK
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1907-1914
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1907-1914
Neutralization of IL-18 by IL-18 binding protein ameliorates bleomycin-induced pulmonary fibrosis via inhibition of epithelial-mesenchymal transition.
Zhang LM, Zhang Y, Fei C, Zhang J, Wang L, Yi ZW, Gao G
Biochemical and biophysical research communications 2019 Jan 8;508(2):660-666
Biochemical and biophysical research communications 2019 Jan 8;508(2):660-666
Resveratrol Attenuates Pressure Overload-Induced Cardiac Fibrosis and Diastolic Dysfunction via PTEN/AKT/Smad2/3 and NF-κB Signaling Pathways.
Zou LX, Chen C, Yan X, Lin QY, Fang J, Li PB, Han X, Wang QS, Guo SB, Li HH, Zhang YL
Molecular nutrition & food research 2019 Dec;63(24):e1900418
Molecular nutrition & food research 2019 Dec;63(24):e1900418
Interleukin-9 blockage reduces early hepatic granuloma formation and fibrosis during Schistosoma japonicum infection in mice.
Zhan T, Ma H, Jiang S, Zhong Z, Wang X, Li C, Yu D, Liu L, Xu J, Xia C
Immunology 2019 Dec;158(4):296-303
Immunology 2019 Dec;158(4):296-303
Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway.
Yang R, Jia Q, Ma SF, Wang Y, Mehmood S, Chen Y
International journal of molecular medicine 2019 Aug;44(2):549-558
International journal of molecular medicine 2019 Aug;44(2):549-558
LncRNA PCFL promotes cardiac fibrosis via miR-378/GRB2 pathway following myocardial infarction.
Sun F, Zhuang Y, Zhu H, Wu H, Li D, Zhan L, Yang W, Yuan Y, Xie Y, Yang S, Luo S, Jiang W, Zhang J, Pan Z, Lu Y
Journal of molecular and cellular cardiology 2019 Aug;133:188-198
Journal of molecular and cellular cardiology 2019 Aug;133:188-198
Anti-inflammatory effects of hederagenin on diabetic cardiomyopathy via inhibiting NF-κB and Smads signaling pathways in a type-2 diabetic mice model.
Li Y, Dong J, Shang Y, Zhao Q, Li P, Wu B
RSC advances 2019 Aug 19;9(45):26238-26247
RSC advances 2019 Aug 19;9(45):26238-26247
IMM-H007 improves heart function via reducing cardiac fibrosis.
Ge W, Zhang W, Gao R, Li B, Zhu H, Wang J
European journal of pharmacology 2019 Aug 15;857:172442
European journal of pharmacology 2019 Aug 15;857:172442
Empagliflozin prevents cardiomyopathy via sGC-cGMP-PKG pathway in type 2 diabetes mice.
Xue M, Li T, Wang Y, Chang Y, Cheng Y, Lu Y, Liu X, Xu L, Li X, Yu X, Sun B, Chen L
Clinical science (London, England : 1979) 2019 Aug 15;133(15):1705-1720
Clinical science (London, England : 1979) 2019 Aug 15;133(15):1705-1720
Calhex(231) Alleviates High Glucose-Induced Myocardial Fibrosis via Inhibiting Itch-Ubiquitin Proteasome Pathway in Vitro.
Yuan H, Xu J, Xu X, Gao T, Wang Y, Fan Y, Hu J, Shao Y, Zhao B, Li H, Sun J, Xu C
Biological & pharmaceutical bulletin 2019 Aug 1;42(8):1337-1344
Biological & pharmaceutical bulletin 2019 Aug 1;42(8):1337-1344
Catabolic changes of rat temporomandibular joint discs induced by unilateral anterior crossbite.
Zhang HY, Xie MJ, Yang HX, Liu X, Ren HT, Zhang M, Lu L, Liu XD, Zhang J, Wang MQ
Journal of oral rehabilitation 2019 Apr;46(4):340-348
Journal of oral rehabilitation 2019 Apr;46(4):340-348
Liraglutide prevents β-cell apoptosis via inactivation of NOX2 and its related signaling pathway.
Ding M, Fang QH, Cui YT, Shen QL, Liu Q, Wang PH, Yu DM, Li CJ
Journal of diabetes and its complications 2019 Apr;33(4):267-277
Journal of diabetes and its complications 2019 Apr;33(4):267-277
Inhibition of SIRT2 Alleviates Fibroblast Activation and Renal Tubulointerstitial Fibrosis via MDM2.
He FF, You RY, Ye C, Lei CT, Tang H, Su H, Zhang C
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(2):451-460
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(2):451-460
Flavonoid Extract from Propolis Inhibits Cardiac Fibrosis Triggered by Myocardial Infarction through Upregulation of SIRT1.
Wang Q, Sui X, Sui DJ, Yang P
Evidence-based complementary and alternative medicine : eCAM 2018;2018:4957573
Evidence-based complementary and alternative medicine : eCAM 2018;2018:4957573
Critical in vivo roles of WNT10A in wound healing by regulating collagen expression/synthesis in WNT10A-deficient mice.
Wang KY, Yamada S, Izumi H, Tsukamoto M, Nakashima T, Tasaki T, Guo X, Uramoto H, Sasaguri Y, Kohno K
PloS one 2018;13(3):e0195156
PloS one 2018;13(3):e0195156
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Wang Q, Zang W, Han L, Yang L, Ye S, Ouyang J, Zhang C, Bi Y, Zhang C, Bian H
Chinese medicine 2018;13:17
Chinese medicine 2018;13:17
TGF-β1/Smad3 signaling promotes collagen synthesis in pulmonary artery smooth muscle by down-regulating miR-29b.
Wang T, Li Y, Chen J, Xie L, Xiao T
International journal of clinical and experimental pathology 2018;11(12):5592-5601
International journal of clinical and experimental pathology 2018;11(12):5592-5601
Antifibrotic Agent Pirfenidone Protects against Development of Radiation-Induced Pulmonary Fibrosis in a Murine Model.
Qin W, Liu B, Yi M, Li L, Tang Y, Wu B, Yuan X
Radiation research 2018 Oct;190(4):396-403
Radiation research 2018 Oct;190(4):396-403
Novel formononetin-7-sal ester ameliorates pulmonary fibrosis via MEF2c signaling pathway.
Zhao X, Qu G, Song C, Li R, Liu W, Lv C, Song X, Zhang J, Li M
Toxicology and applied pharmacology 2018 Oct 1;356:15-24
Toxicology and applied pharmacology 2018 Oct 1;356:15-24
Role of miR-29 in mediating offspring lung phenotype in a rodent model of intrauterine growth restriction.
Chuang TD, Sakurai R, Gong M, Khorram O, Rehan VK
American journal of physiology. Regulatory, integrative and comparative physiology 2018 Nov 1;315(5):R1017-R1026
American journal of physiology. Regulatory, integrative and comparative physiology 2018 Nov 1;315(5):R1017-R1026
Glutaminolysis Promotes Collagen Translation and Stability via α-Ketoglutarate-mediated mTOR Activation and Proline Hydroxylation.
Ge J, Cui H, Xie N, Banerjee S, Guo S, Dubey S, Barnes S, Liu G
American journal of respiratory cell and molecular biology 2018 Mar;58(3):378-390
American journal of respiratory cell and molecular biology 2018 Mar;58(3):378-390
Overexpression of collagen type III in injured myocardium prevents cardiac systolic dysfunction by changing the balance of collagen distribution.
Uchinaka A, Yoshida M, Tanaka K, Hamada Y, Mori S, Maeno Y, Miyagawa S, Sawa Y, Nagata K, Yamamoto H, Kawaguchi N
The Journal of thoracic and cardiovascular surgery 2018 Jul;156(1):217-226.e3
The Journal of thoracic and cardiovascular surgery 2018 Jul;156(1):217-226.e3
Circular RNA DLGAP4 Ameliorates Ischemic Stroke Outcomes by Targeting miR-143 to Regulate Endothelial-Mesenchymal Transition Associated with Blood-Brain Barrier Integrity.
Bai Y, Zhang Y, Han B, Yang L, Chen X, Huang R, Wu F, Chao J, Liu P, Hu G, Zhang JH, Yao H
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Jan 3;38(1):32-50
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Jan 3;38(1):32-50
Deep Coverage Tissue and Cellular Proteomics Revealed IL-1β Can Independently Induce the Secretion of TNF-Associated Proteins from Human Synoviocytes.
Tang S, Deng S, Guo J, Chen X, Zhang W, Cui Y, Luo Y, Yan Z, He QY, Shen S, Wang T
Journal of immunology (Baltimore, Md. : 1950) 2018 Jan 15;200(2):821-833
Journal of immunology (Baltimore, Md. : 1950) 2018 Jan 15;200(2):821-833
Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway.
Xiao Y, Ye J, Zhou Y, Huang J, Liu X, Huang B, Zhu L, Wu B, Zhang G, Cai Y
Archives of biochemistry and biophysics 2018 Feb 15;640:37-46
Archives of biochemistry and biophysics 2018 Feb 15;640:37-46
Klotho gene-modified BMSCs showed elevated antifibrotic effects by inhibiting the Wnt/β-catenin pathway in kidneys after acute injury.
Zhang F, Wan X, Cao YZ, Sun D, Cao CC
Cell biology international 2018 Dec;42(12):1670-1679
Cell biology international 2018 Dec;42(12):1670-1679
Retracted: 'Anti-fibrotic actions of Ghrelin by inhibition of the NADPH oxidase-ROS signaling pathway' by Qian Wang, Xin Sui, Rui Chen, Peiyong Ma, Tao Ding, Dianjun Sui, and Ping Yang.
Clinical and experimental pharmacology & physiology 2018 Aug;45(8):885
Thymoquinone protects against cardiac damage from doxorubicin-induced heart failure in Sprague-Dawley rats.
Pei Z, Hu J, Bai Q, Liu B, Cheng D, Liu H, Na R, Yu Q
RSC advances 2018 Apr 17;8(26):14633-14639
RSC advances 2018 Apr 17;8(26):14633-14639
MDM2 Contributes to High Glucose-Induced Glomerular Mesangial Cell Proliferation and Extracellular Matrix Accumulation via Notch1.
Lei CT, Tang H, Ye C, You CQ, Zhang J, Zhang CY, Xiong W, Su H, Zhang C
Scientific reports 2017 Sep 4;7(1):10393
Scientific reports 2017 Sep 4;7(1):10393
Development of a new biodegradable operative clip made of a magnesium alloy: Evaluation of its safety and tolerability for canine cholecystectomy.
Yoshida T, Fukumoto T, Urade T, Kido M, Toyama H, Asari S, Ajiki T, Ikeo N, Mukai T, Ku Y
Surgery 2017 Jun;161(6):1553-1560
Surgery 2017 Jun;161(6):1553-1560
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.
Sang L, Wang XM, Xu DY, Sang LX, Han Y, Jiang LY
World journal of gastroenterology 2017 Dec 21;23(47):8334-8344
World journal of gastroenterology 2017 Dec 21;23(47):8334-8344
Relaxin alleviates TGFβ1-induced cardiac fibrosis via inhibition of Stat3-dependent autophagy.
Yuan Y, Zhang Y, Han X, Li Y, Zhao X, Sheng L, Li Y
Biochemical and biophysical research communications 2017 Dec 2;493(4):1601-1607
Biochemical and biophysical research communications 2017 Dec 2;493(4):1601-1607
Crucial Role of miR-433 in Regulating Cardiac Fibrosis.
Tao L, Bei Y, Chen P, Lei Z, Fu S, Zhang H, Xu J, Che L, Chen X, Sluijter JP, Das S, Cretoiu D, Xu B, Zhong J, Xiao J, Li X
Theranostics 2016;6(12):2068-2083
Theranostics 2016;6(12):2068-2083
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse skin tissue were subjected to SDS PAGE followed by western blot with 22734-1-AP( COL3A1 Antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Collagen Type III antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Collagen Type III. This antibody recognizes human, mouse antigen. The Collagen Type III antibody has been validated for the following applications: ELISA, IHC, WB analysis.
