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- Antibody Data
- Antigen structure
- References [45]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- 13548-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13548-1-AP, RRID:AB_2082346
- Product name
- Collagen Type III (C-terminal) antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Collagen Type III (C-terminal) antibody (Cat. #13548-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: IHC, ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Long Non-coding RNA ZFAS1 Regulates Fibrosis and Scortosis in the Cell Model of Diabetic Nephropathy Through miR-525-5p/SGK1 Axis.
Cadmium exposure induces histological damage and cytotoxicity in the cardiovascular system of mice.
Amlexanox and Forskolin Prevents Isoproterenol-Induced Cardiomyopathy by Subduing Cardiomyocyte Hypertrophy and Maladaptive Inflammatory Responses.
Isoproterenol-Induced Cardiomyopathy Recovery Intervention: Amlexanox and Forskolin Enhances the Resolution of Catecholamine Stress-Induced Maladaptive Myocardial Remodeling.
Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy.
Substrate Stiffness and Stretch Regulate Profibrotic Mechanosignaling in Pulmonary Arterial Adventitial Fibroblasts.
The Antiproliferative and Antifibrotic Effects of Cisplatin on Primary Human Vocal Fold Fibroblasts.
Choline Attenuates Cardiac Fibrosis by Inhibiting p38MAPK Signaling Possibly by Acting on M(3) Muscarinic Acetylcholine Receptor.
Immunohistochemical validation of COL3A1, GPR158 and PITHD1 as prognostic biomarkers in early-stage ovarian carcinomas.
Rutaecarpine prevents hypertensive cardiac hypertrophy involving the inhibition of Nox4-ROS-ADAM17 pathway.
Aligned topography mediated cell elongation reverses pathological phenotype of in vitro cultured keloid fibroblasts.
High cholesterol inhibits tendon-related gene expressions in tendon-derived stem cells through reactive oxygen species-activated nuclear factor-κB signaling.
Annexin A1 is elevated in patients with COPD and affects lung fibroblast function.
Interleukin-6 Promotes Proliferation but Inhibits Tenogenic Differentiation via the Janus Kinase/Signal Transducers and Activators of Transcription 3 (JAK/STAT3) Pathway in Tendon-Derived Stem Cells.
Aucubin Protects against TGFβ1-Induced Cardiac Fibroblasts Activation by Mediating the AMPKα/mTOR Signaling Pathway.
Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling.
Interleukin‑10 promotes proliferation and migration, and inhibits tendon differentiation via the JAK/Stat3 pathway in tendon‑derived stem cells in vitro.
Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting IκBα/NFκB and Enhancing Nrf2/HO-1.
Synthesis of the novel PARP-1 inhibitor AG-690/11026014 and its protective effects on angiotensin II-induced mouse cardiac remodeling.
RelA/p65 inhibition prevents tendon adhesion by modulating inflammation, cell proliferation, and apoptosis.
Evodiamine attenuates TGF-β1-induced fibroblast activation and endothelial to mesenchymal transition.
Glucose variability aggravates cardiac fibrosis by altering AKT signalling path.
Muscarinic receptor mediated signaling pathways in hepatocytes from CCL4 - induced liver fibrotic rat.
Expression of muscarinic acetylcholine receptors in hepatocytes from rat fibrotic liver.
Ascorbate starvation alters endoplasmic reticulum-resident enzymes in cardiac fibroblasts, priming them for increased procollagen secretion.
Src Homology 2 Domain-Containing Inositol 5'-Phosphatase Ameliorates High Glucose-Induced Extracellular Matrix Deposition via the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway in Renal Tubular Epithelial Cells.
The vascular protective effects of Anoectochilus roxburghii polysaccharose under high glucose conditions.
MDM2 mediates fibroblast activation and renal tubulointerstitial fibrosis via a p53-independent pathway.
Exogenous H2S modulates mitochondrial fusion-fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state.
Sonodynamic Therapy Inhibits Fibrogenesis in Rat Cardiac Fibroblasts Induced by TGF-β1.
Curcumin protects against myocardial infarction-induced cardiac fibrosis via SIRT1 activation in vivo and in vitro.
Tetramethylpyrazine Attenuates Transdifferentiation of TGF-β2-Treated Human Tenon's Fibroblasts.
MAD2B promotes tubular epithelial-to-mesenchymal transition and renal tubulointerstitial fibrosis via Skp2.
PPAR-γ is involved in the protective effect of 2,3,4',5-tetrahydroxystilbene-2-O-beta-D-glucoside against cardiac fibrosis in pressure-overloaded rats.
PTEN Regulates Renal Extracellular Matrix Deposit via Increased CTGF in Diabetes Mellitus.
Deletion of interleukin-6 alleviated interstitial fibrosis in streptozotocin-induced diabetic cardiomyopathy of mice through affecting TGFβ1 and miR-29 pathways.
Mechanisms underlying aberrant expression of miR-29c in uterine leiomyoma.
Epithelial but not stromal expression of collagen alpha-1(III) is a diagnostic and prognostic indicator of colorectal carcinoma.
IL-27 attenuates the TGF-β1-induced proliferation, differentiation and collagen synthesis in lung fibroblasts.
Protective effects of triptolide on TLR4 mediated autoimmune and inflammatory response induced myocardial fibrosis in diabetic cardiomyopathy.
A fundamental study on the dynamics of multiple biomarkers in mouse excisional wounds for wound age estimation.
miR-29c induction contributes to downregulation of vascular extracellular matrix proteins by glucocorticoids.
Long-term effects of maternal undernutrition on offspring carotid artery remodeling: role of miR-29c.
Identification of colonic fibroblast secretomes reveals secretory factors regulating colon cancer cell proliferation.
Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced cardiac hypertrophy and fibrosis in vivo.
Zhuang L, Jin G, Wang Q, Ge X, Pei X
Applied biochemistry and biotechnology 2024 Jul;196(7):3731-3746
Applied biochemistry and biotechnology 2024 Jul;196(7):3731-3746
Cadmium exposure induces histological damage and cytotoxicity in the cardiovascular system of mice.
Chou SH, Lin HC, Chen SW, Tai YT, Jung SM, Ko FH, Pang JS, Chu PH
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113740
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113740
Amlexanox and Forskolin Prevents Isoproterenol-Induced Cardiomyopathy by Subduing Cardiomyocyte Hypertrophy and Maladaptive Inflammatory Responses.
Adzika GK, Hou H, Adekunle AO, Rizvi R, Adzraku SY, Li K, Deng QM, Mprah R, Ndzie Noah ML, Adu-Amankwaah J, Machuki JO, Shang W, Ma T, Koda S, Ma X, Sun H
Frontiers in cell and developmental biology 2021;9:719351
Frontiers in cell and developmental biology 2021;9:719351
Isoproterenol-Induced Cardiomyopathy Recovery Intervention: Amlexanox and Forskolin Enhances the Resolution of Catecholamine Stress-Induced Maladaptive Myocardial Remodeling.
Adzika GK, Hou H, Adekunle AO, Rizvi R, Adu-Amankwaah J, Shang W, Li K, Deng QM, Mprah R, Ndzie Noah ML, Sun H
Frontiers in cardiovascular medicine 2021;8:719805
Frontiers in cardiovascular medicine 2021;8:719805
Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy.
Chen H, Qian Z, Zhang S, Tang J, Fang L, Jiang F, Ge D, Chang J, Cao J, Yang L, Cao X
Redox biology 2021 Jan;38:101774
Redox biology 2021 Jan;38:101774
Substrate Stiffness and Stretch Regulate Profibrotic Mechanosignaling in Pulmonary Arterial Adventitial Fibroblasts.
Wang A, Cao S, Stowe JC, Valdez-Jasso D
Cells 2021 Apr 23;10(5)
Cells 2021 Apr 23;10(5)
The Antiproliferative and Antifibrotic Effects of Cisplatin on Primary Human Vocal Fold Fibroblasts.
Xu H, Wang Q, Fan GK
ORL; journal for oto-rhino-laryngology and its related specialties 2020;82(4):188-200
ORL; journal for oto-rhino-laryngology and its related specialties 2020;82(4):188-200
Choline Attenuates Cardiac Fibrosis by Inhibiting p38MAPK Signaling Possibly by Acting on M(3) Muscarinic Acetylcholine Receptor.
Zhao L, Chen T, Hang P, Li W, Guo J, Pan Y, Du J, Zheng Y, Du Z
Frontiers in pharmacology 2019;10:1386
Frontiers in pharmacology 2019;10:1386
Immunohistochemical validation of COL3A1, GPR158 and PITHD1 as prognostic biomarkers in early-stage ovarian carcinomas.
Engqvist H, Parris TZ, Kovács A, Nemes S, Werner Rönnerman E, De Lara S, Biermann J, Sundfeldt K, Karlsson P, Helou K
BMC cancer 2019 Sep 18;19(1):928
BMC cancer 2019 Sep 18;19(1):928
Rutaecarpine prevents hypertensive cardiac hypertrophy involving the inhibition of Nox4-ROS-ADAM17 pathway.
Zeng SY, Yang L, Lu HQ, Yan QJ, Gao L, Qin XP
Journal of cellular and molecular medicine 2019 Jun;23(6):4196-4207
Journal of cellular and molecular medicine 2019 Jun;23(6):4196-4207
Aligned topography mediated cell elongation reverses pathological phenotype of in vitro cultured keloid fibroblasts.
Huang J, Tu T, Wang W, Gao Z, Zhou G, Zhang W, Wu X, Liu W
Journal of biomedical materials research. Part A 2019 Jul;107(7):1366-1378
Journal of biomedical materials research. Part A 2019 Jul;107(7):1366-1378
High cholesterol inhibits tendon-related gene expressions in tendon-derived stem cells through reactive oxygen species-activated nuclear factor-κB signaling.
Li K, Deng G, Deng Y, Chen S, Wu H, Cheng C, Zhang X, Yu B, Zhang K
Journal of cellular physiology 2019 Aug;234(10):18017-18028
Journal of cellular physiology 2019 Aug;234(10):18017-18028
Annexin A1 is elevated in patients with COPD and affects lung fibroblast function.
Lai T, Li Y, Mai Z, Wen X, Lv Y, Xie Z, Lv Q, Chen M, Wu D, Wu B
International journal of chronic obstructive pulmonary disease 2018;13:473-486
International journal of chronic obstructive pulmonary disease 2018;13:473-486
Interleukin-6 Promotes Proliferation but Inhibits Tenogenic Differentiation via the Janus Kinase/Signal Transducers and Activators of Transcription 3 (JAK/STAT3) Pathway in Tendon-Derived Stem Cells.
Chen S, Deng G, Li K, Zheng H, Wang G, Yu B, Zhang K
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 16;24:1567-1573
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 16;24:1567-1573
Aucubin Protects against TGFβ1-Induced Cardiac Fibroblasts Activation by Mediating the AMPKα/mTOR Signaling Pathway.
Xiao Y, Chang W, Wu QQ, Jiang XH, Duan MX, Jin YG, Tang QZ
Planta medica 2018 Jan;84(2):91-99
Planta medica 2018 Jan;84(2):91-99
Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling.
Zhang X, Ma ZG, Yuan YP, Xu SC, Wei WY, Song P, Kong CY, Deng W, Tang QZ
Cell death & disease 2018 Jan 24;9(2):102
Cell death & disease 2018 Jan 24;9(2):102
Interleukin‑10 promotes proliferation and migration, and inhibits tendon differentiation via the JAK/Stat3 pathway in tendon‑derived stem cells in vitro.
Deng G, Li K, Chen S, Chen P, Zheng H, Yu B, Zhang K
Molecular medicine reports 2018 Dec;18(6):5044-5052
Molecular medicine reports 2018 Dec;18(6):5044-5052
Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting IκBα/NFκB and Enhancing Nrf2/HO-1.
Liao HH, Zhu JX, Feng H, Ni J, Zhang N, Chen S, Liu HJ, Yang Z, Deng W, Tang QZ
Oxidative medicine and cellular longevity 2017;2017:8370593
Oxidative medicine and cellular longevity 2017;2017:8370593
Synthesis of the novel PARP-1 inhibitor AG-690/11026014 and its protective effects on angiotensin II-induced mouse cardiac remodeling.
Feng GS, Zhu CG, Li ZM, Wang PX, Huang Y, Liu M, He P, Lou LL, Chen SR, Liu PQ
Acta pharmacologica Sinica 2017 May;38(5):638-650
Acta pharmacologica Sinica 2017 May;38(5):638-650
RelA/p65 inhibition prevents tendon adhesion by modulating inflammation, cell proliferation, and apoptosis.
Chen S, Jiang S, Zheng W, Tu B, Liu S, Ruan H, Fan C
Cell death & disease 2017 Mar 30;8(3):e2710
Cell death & disease 2017 Mar 30;8(3):e2710
Evodiamine attenuates TGF-β1-induced fibroblast activation and endothelial to mesenchymal transition.
Wu QQ, Xiao Y, Jiang XH, Yuan Y, Yang Z, Chang W, Bian ZY, Tang QZ
Molecular and cellular biochemistry 2017 Jun;430(1-2):81-90
Molecular and cellular biochemistry 2017 Jun;430(1-2):81-90
Glucose variability aggravates cardiac fibrosis by altering AKT signalling path.
Ying C, Liu T, Ling H, Cheng M, Zhou X, Wang S, Mao Y, Chen L, Zhang R, Li W
Diabetes & vascular disease research 2017 Jul;14(4):327-335
Diabetes & vascular disease research 2017 Jul;14(4):327-335
Muscarinic receptor mediated signaling pathways in hepatocytes from CCL4 - induced liver fibrotic rat.
Luo L, Xi C, Xu T, Zhang G, Qun E, Zhang W
European journal of pharmacology 2017 Jul 15;807:109-116
European journal of pharmacology 2017 Jul 15;807:109-116
Expression of muscarinic acetylcholine receptors in hepatocytes from rat fibrotic liver.
Luo L, Xu T, Wang P, Mao L, Xi C, Huang J, Zhang W
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 2017 Feb;69(2):73-81
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 2017 Feb;69(2):73-81
Ascorbate starvation alters endoplasmic reticulum-resident enzymes in cardiac fibroblasts, priming them for increased procollagen secretion.
Cowling RT, Park JI, Sotimehin AE, Greenberg BH
Journal of molecular and cellular cardiology 2017 Dec;113:1-8
Journal of molecular and cellular cardiology 2017 Dec;113:1-8
Src Homology 2 Domain-Containing Inositol 5'-Phosphatase Ameliorates High Glucose-Induced Extracellular Matrix Deposition via the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway in Renal Tubular Epithelial Cells.
Li F, Li L, Hao J, Liu S, Duan H
Journal of cellular biochemistry 2017 Aug;118(8):2271-2284
Journal of cellular biochemistry 2017 Aug;118(8):2271-2284
The vascular protective effects of Anoectochilus roxburghii polysaccharose under high glucose conditions.
Liu ZL, Zhang JG, Liu Q, Yi LT, Li YM, Li Y
Journal of ethnopharmacology 2017 Apr 18;202:192-199
Journal of ethnopharmacology 2017 Apr 18;202:192-199
MDM2 mediates fibroblast activation and renal tubulointerstitial fibrosis via a p53-independent pathway.
Ye C, Tang H, Zhao Z, Lei CT, You CQ, Zhang J, Gao P, He FF, Chen S, Wang YM, Zhang C, Su H
American journal of physiology. Renal physiology 2017 Apr 1;312(4):F760-F768
American journal of physiology. Renal physiology 2017 Apr 1;312(4):F760-F768
Exogenous H2S modulates mitochondrial fusion-fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state.
Sun A, Wang Y, Liu J, Yu X, Sun Y, Yang F, Dong S, Wu J, Zhao Y, Xu C, Lu F, Zhang W
Cell & bioscience 2016;6:36
Cell & bioscience 2016;6:36
Sonodynamic Therapy Inhibits Fibrogenesis in Rat Cardiac Fibroblasts Induced by TGF-β1.
Guo Y, Dong Z, Shi Y, Wang W, Wang L, Sun J, Sun X, Tian Z, Yao J, Li Z, Cheng J, Tian Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):579-588
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):579-588
Curcumin protects against myocardial infarction-induced cardiac fibrosis via SIRT1 activation in vivo and in vitro.
Xiao J, Sheng X, Zhang X, Guo M, Ji X
Drug design, development and therapy 2016;10:1267-77
Drug design, development and therapy 2016;10:1267-77
Tetramethylpyrazine Attenuates Transdifferentiation of TGF-β2-Treated Human Tenon's Fibroblasts.
Cai X, Yang Y, Chen P, Ye Y, Liu X, Wu K, Yu M
Investigative ophthalmology & visual science 2016 Sep 1;57(11):4740-8
Investigative ophthalmology & visual science 2016 Sep 1;57(11):4740-8
MAD2B promotes tubular epithelial-to-mesenchymal transition and renal tubulointerstitial fibrosis via Skp2.
Tang H, Fan D, Lei CT, Ye C, Gao P, Chen S, Meng XF, Su H, Zhang C
Journal of molecular medicine (Berlin, Germany) 2016 Nov;94(11):1297-1307
Journal of molecular medicine (Berlin, Germany) 2016 Nov;94(11):1297-1307
PPAR-γ is involved in the protective effect of 2,3,4',5-tetrahydroxystilbene-2-O-beta-D-glucoside against cardiac fibrosis in pressure-overloaded rats.
Peng Y, Zeng Y, Xu J, Huang XL, Zhang W, Xu XL
European journal of pharmacology 2016 Nov 15;791:105-114
European journal of pharmacology 2016 Nov 15;791:105-114
PTEN Regulates Renal Extracellular Matrix Deposit via Increased CTGF in Diabetes Mellitus.
Zhu L, Zhao S, Liu S, Liu Q, Li F, Hao J
Journal of cellular biochemistry 2016 May;117(5):1187-98
Journal of cellular biochemistry 2016 May;117(5):1187-98
Deletion of interleukin-6 alleviated interstitial fibrosis in streptozotocin-induced diabetic cardiomyopathy of mice through affecting TGFβ1 and miR-29 pathways.
Zhang Y, Wang JH, Zhang YY, Wang YZ, Wang J, Zhao Y, Jin XX, Xue GL, Li PH, Sun YL, Huang QH, Song XT, Zhang ZR, Gao X, Yang BF, Du ZM, Pan ZW
Scientific reports 2016 Mar 14;6:23010
Scientific reports 2016 Mar 14;6:23010
Mechanisms underlying aberrant expression of miR-29c in uterine leiomyoma.
Chuang TD, Khorram O
Fertility and sterility 2016 Jan;105(1):236-45.e1
Fertility and sterility 2016 Jan;105(1):236-45.e1
Epithelial but not stromal expression of collagen alpha-1(III) is a diagnostic and prognostic indicator of colorectal carcinoma.
Wang XQ, Tang ZX, Yu D, Cui SJ, Jiang YH, Zhang Q, Wang J, Yang PY, Liu F
Oncotarget 2016 Feb 23;7(8):8823-38
Oncotarget 2016 Feb 23;7(8):8823-38
IL-27 attenuates the TGF-β1-induced proliferation, differentiation and collagen synthesis in lung fibroblasts.
Dong Z, Zhao X, Tai W, Lei W, Wang Y, Li Z, Zhang T
Life sciences 2016 Feb 1;146:24-33
Life sciences 2016 Feb 1;146:24-33
Protective effects of triptolide on TLR4 mediated autoimmune and inflammatory response induced myocardial fibrosis in diabetic cardiomyopathy.
Guo X, Xue M, Li CJ, Yang W, Wang SS, Ma ZJ, Zhang XN, Wang XY, Zhao R, Chang BC, Chen LM
Journal of ethnopharmacology 2016 Dec 4;193:333-344
Journal of ethnopharmacology 2016 Dec 4;193:333-344
A fundamental study on the dynamics of multiple biomarkers in mouse excisional wounds for wound age estimation.
Wang LL, Zhao R, Liu CS, Liu M, Li SS, Li JY, Jiang SK, Zhang M, Tian ZL, Wang M, Zhang MZ, Guan DW
Journal of forensic and legal medicine 2016 Apr;39:138-46
Journal of forensic and legal medicine 2016 Apr;39:138-46
miR-29c induction contributes to downregulation of vascular extracellular matrix proteins by glucocorticoids.
Chuang TD, Pearce WJ, Khorram O
American journal of physiology. Cell physiology 2015 Jul 15;309(2):C117-25
American journal of physiology. Cell physiology 2015 Jul 15;309(2):C117-25
Long-term effects of maternal undernutrition on offspring carotid artery remodeling: role of miR-29c.
Khorram O, Chuang TD, Pearce WJ
Journal of developmental origins of health and disease 2015 Aug;6(4):342-9
Journal of developmental origins of health and disease 2015 Aug;6(4):342-9
Identification of colonic fibroblast secretomes reveals secretory factors regulating colon cancer cell proliferation.
Chen SX, Xu XE, Wang XQ, Cui SJ, Xu LL, Jiang YH, Zhang Y, Yan HB, Zhang Q, Qiao J, Yang PY, Liu F
Journal of proteomics 2014 Oct 14;110:155-71
Journal of proteomics 2014 Oct 14;110:155-71
Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced cardiac hypertrophy and fibrosis in vivo.
Yang J, Zhu HH, Chen GP, Ye Y, Zhao CZ, Mou Y, Hu SJ
The international journal of biochemistry & cell biology 2013 Mar;45(3):657-66
The international journal of biochemistry & cell biology 2013 Mar;45(3):657-66
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 13548-1-AP(COL3A1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using COL3A1 antibody 13548-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded mouse liver using 13548-1-AP(COL3A1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
