Explore
Validate
LearnTissue expression
Cell line expression
CFH
gene productARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]
Featured antibodies
 GeneTex |
 GTX41629 |
0 references | Monoclonal |
WB
EL
IP
RA
|
Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider