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- Antigen structure
- References [16]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 19529-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19529-1-AP, RRID:AB_10643377
- Product name
- SENP5-Specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SENP5-Specific antibody (Cat. #19529-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth.
SENP5 Attenuates LPS-Induced Acute Lung Injury by Inhibiting Apoptosis of Lung Epithelial Cells Through SLC7A5/mTOR Signaling Pathway.
SENP5 promotes endometrial cancer cell growth by regulating β-catenin deSUMOylation to enhance GPX4-resistance to ferroptosis.
SUMO-Specific Peptidase 5 Promotes Oesophageal Squamous Cell Carcinoma Growth through the NF-κB-SLC1A3 Axis.
IRX3 controls a SUMOylation-dependent differentiation switch in adipocyte precursor cells.
SENP3 protects hepatocyte from pyroptosis during acute liver injury through deSUMOylation of HNRNPL.
Transcription factor E2F4 facilitates SUMOylation to promote HCC progression through interaction with LIN9.
Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia-reperfusion injury.
SENP5 promotes homologous recombination-mediated DNA damage repair in colorectal cancer cells through H2AZ deSUMOylation.
Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress.
SENP7 deSUMOylase-governed transcriptional program coordinates sarcomere assembly and is targeted in muscle atrophy.
The SUMO protease SENP3 regulates mitochondrial autophagy mediated by Fis1.
SUMO proteases SENP3 and SENP5 spatiotemporally regulate the kinase activity of Aurora A.
Drp1 SUMO/deSUMOylation by Senp5 isoforms influences ER tubulation and mitochondrial dynamics to regulate brain development.
A fine-tuning mechanism underlying self-control for autophagy: deSUMOylation of BECN1 by SENP3.
Synaptic localization of the SUMOylation-regulating protease SENP5 in the adult mouse brain.
Chen X, Gong X, Zhang J, Liu W
Oncology letters 2026 Feb;31(2):51
Oncology letters 2026 Feb;31(2):51
SENP5 Attenuates LPS-Induced Acute Lung Injury by Inhibiting Apoptosis of Lung Epithelial Cells Through SLC7A5/mTOR Signaling Pathway.
He Y, Zhang H, Gu J, Ju M, Zhang C
Frontiers in bioscience (Landmark edition) 2025 Oct 29;30(10):45811
Frontiers in bioscience (Landmark edition) 2025 Oct 29;30(10):45811
SENP5 promotes endometrial cancer cell growth by regulating β-catenin deSUMOylation to enhance GPX4-resistance to ferroptosis.
Wang Z, Zhang Y, Zhang Y, Deng Q, Xi Y, He W, Ma X
European journal of medical research 2025 May 24;30(1):411
European journal of medical research 2025 May 24;30(1):411
SUMO-Specific Peptidase 5 Promotes Oesophageal Squamous Cell Carcinoma Growth through the NF-κB-SLC1A3 Axis.
Du C, Hu Y, Yang X, Zhang Z, Gu J, Zhang T, Wang R, Zhang S, Tan L, Yu G
Frontiers in bioscience (Landmark edition) 2025 Jan 22;30(1):27047
Frontiers in bioscience (Landmark edition) 2025 Jan 22;30(1):27047
IRX3 controls a SUMOylation-dependent differentiation switch in adipocyte precursor cells.
Bjune JI, Laber S, Lawrence-Archer L, Nothnagel PMC, Yamada S, Zhao X, Panahandeh Strømland P, Al-Sharabi N, Mustafa K, Njølstad PR, Claussnitzer M, Cox RD, Chymkowitch P, Mellgren G, Dankel SN
Nature communications 2025 Aug 6;16(1):7248
Nature communications 2025 Aug 6;16(1):7248
SENP3 protects hepatocyte from pyroptosis during acute liver injury through deSUMOylation of HNRNPL.
Xiong X, Zhi Y, Yang N, Zhao W, Wang S, Zhu H, Tang J, Yi J, Sun X, Yang J
iScience 2025 Aug 15;28(8):113067
iScience 2025 Aug 15;28(8):113067
Transcription factor E2F4 facilitates SUMOylation to promote HCC progression through interaction with LIN9.
Ma Z, Li Q, Wang W, Deng Z
International journal of oncology 2024 Oct;65(4)
International journal of oncology 2024 Oct;65(4)
Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia-reperfusion injury.
Chen X, Yang T, Zhou Y, Mei Z, Zhang W
CNS neuroscience & therapeutics 2024 Apr;30(4):e14725
CNS neuroscience & therapeutics 2024 Apr;30(4):e14725
SENP5 promotes homologous recombination-mediated DNA damage repair in colorectal cancer cells through H2AZ deSUMOylation.
Liu T, Wang H, Chen Y, Wan Z, Du Z, Shen H, Yu Y, Ma S, Xu Y, Li Z, Yu N, Zhang F, Cao K, Cai J, Zhang W, Gao F, Yang Y
Journal of experimental & clinical cancer research : CR 2023 Sep 8;42(1):234
Journal of experimental & clinical cancer research : CR 2023 Sep 8;42(1):234
Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress.
Liu Y, Liu K, Thorne RF, Shi R, Zhang Q, Wu M, Liu L
Cell reports 2023 Feb 28;42(2):112041
Cell reports 2023 Feb 28;42(2):112041
SENP7 deSUMOylase-governed transcriptional program coordinates sarcomere assembly and is targeted in muscle atrophy.
Amrute-Nayak M, Gand LV, Khan B, Holler T, Kefalakes E, Kosanke M, Kraft T, Nayak A
Cell reports 2022 Nov 22;41(8):111702
Cell reports 2022 Nov 22;41(8):111702
The SUMO protease SENP3 regulates mitochondrial autophagy mediated by Fis1.
Waters E, Wilkinson KA, Harding AL, Carmichael RE, Robinson D, Colley HE, Guo C
EMBO reports 2022 Feb 3;23(2):e48754
EMBO reports 2022 Feb 3;23(2):e48754
SUMO proteases SENP3 and SENP5 spatiotemporally regulate the kinase activity of Aurora A.
Yu B, Lin Q, Huang C, Zhang B, Wang Y, Jiang Q, Zhang C, Yi J
Journal of cell science 2021 Jul 1;134(13)
Journal of cell science 2021 Jul 1;134(13)
Drp1 SUMO/deSUMOylation by Senp5 isoforms influences ER tubulation and mitochondrial dynamics to regulate brain development.
Yamada S, Sato A, Ishihara N, Akiyama H, Sakakibara SI
iScience 2021 Dec 17;24(12):103484
iScience 2021 Dec 17;24(12):103484
A fine-tuning mechanism underlying self-control for autophagy: deSUMOylation of BECN1 by SENP3.
Liu K, Guo C, Lao Y, Yang J, Chen F, Zhao Y, Yang Y, Yang J, Yi J
Autophagy 2020 Jun;16(6):975-990
Autophagy 2020 Jun;16(6):975-990
Synaptic localization of the SUMOylation-regulating protease SENP5 in the adult mouse brain.
Akiyama H, Nakadate K, Sakakibara SI
The Journal of comparative neurology 2018 Apr 15;526(6):990-1005
The Journal of comparative neurology 2018 Apr 15;526(6):990-1005
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 19529-1-AP(SENP5-Specific antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 19529-1-AP(SENP5-Specific antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SENP5-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human SENP5-Specific. This antibody recognizes human, mouse, rat antigen. The SENP5-Specific antibody has been validated for the following applications: ELISA, WB, IHC analysis.
