67448-1-Ig

antibody from Proteintech Group

Targeting: BDH1 BDH, SDR9C1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

67448-1-Ig

Provider

Proteintech Group

Product name

BDH1 antibody

Antibody type

Monoclonal

Description

BDH1 antibody (Cat. #67448-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse, Rat, Pig and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat, Porcine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2C3D4

Vial size

20ul, 150ul

References

Submitted references

BDH1 drives ovarian cancer progression by regulating cell cycling and stemness maintenance through Wnt/β-catenin signaling.

Sun S, Guo L, Zhu H
The International journal of biological markers 2026 Mar 26;:3936155261435599

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β-hydroxybutyrate enhances the metabolic fitness of CAR T cells in cancer.

Liu S, Guruprasad P, Ramasubramanian R, Madhu B, Paruzzo L, Han K, Kelly A, Shestov A, Xu HN, Carturan A, Zhou C, Amses KR, Afriat A, Litichevskiy L, Lin J, Dubowitz E, Tangal N, Zhang J, McSween A, Tan M, Stella F, Lee A, Nason S, Hua X, Schneider M, Sleeman M, Zhang Y, Gabrielli G, Yang Z, Pajarillo R, Patel R, Ghilardi G, Patel V, Joshi A, Jiang S, Jiang Y, Porazzi P, Tchou JC, Keith B, Li M, Chong E, Schuster SJ, Milone M, Rabinowitz J, O'Connor RS, Thaiss CA, Levy M, Ruella M
Cell 2026 Mar 19;189(6):1701-1716.e24

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An alternative route for β-hydroxybutyrate metabolism supports cytosolic acetyl-CoA synthesis in cancer cells.

Kaluba FC, Rogers TJ, Jeong YJ, House R'J, Waldhart A, Sokol KH, Daniels SR, Lee CJ, Longo J, Johnson A, Sartori VJ, Sheldon RD, Jones RG, Lien EC
Nature metabolism 2025 Oct;7(10):2033-2044

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Parabacteroides distasonis promotes liver regeneration by increasing β-hydroxybutyric acid (BHB) production and BHB-driven STAT3 signals.

Guo M, Jiang X, Ouyang H, Zhang X, Zhang S, Wang P, Bi G, Wu T, Zhou W, Liang F, Yang X, Fan S, Fang JH, Chen P, Bi H
Acta pharmaceutica Sinica. B 2025 Mar;15(3):1430-1446

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Putative Role of Fatty Acid Metabolic Therapy Using Ketogenic Diet and HIF-1α Inhibition in Hepatocellular Carcinoma: Evidence from an In Vitro Study.

Kimura N, Kitajima Y, Higure K, Matsufuji S, Ikeda S, Furukawa S, Yukimoto K, Tanaka T, Noshiro H
International journal of molecular sciences 2025 Dec 5;26(24)

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An alternative route for β-hydroxybutyrate metabolism supports fatty acid synthesis in cancer cells.

Kaluba FC, Rogers TJ, Jeong YJ, Waldhart A, Sokol KH, Lee CJ, Daniels SR, Longo J, Johnson A, Sheldon RD, Jones RG, Lien EC
bioRxiv : the preprint server for biology 2024 Nov 3;

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BDH1-mediated LRRC31 regulation dependent on histone lysine β-hydroxybutyrylation to promote lung adenocarcinoma progression.

Huang J, Liang L, Jiang S, Liu Y, He H, Sun X, Li Y, Xie L, Tao Y, Cong L, Jiang Y
MedComm 2023 Dec;4(6):e449

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Frataxin controls ketone body metabolism through regulation of OXCT1.

Dong YN, Mesaros C, Xu P, Mercado-Ayón E, Halawani S, Ngaba LV, Warren N, Sleiman P, Rodden LN, Schadt KA, Blair IA, Lynch DR
PNAS nexus 2022 Jul;1(3):pgac142