BS8607

antibody from Bioworld Technology, Inc
Targeting: PRKAB2
Provider product page for BS8607
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8607 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PRKAB2 polyclonal antibody
Antibody type
Polyclonal
Antigen
AMPKÉÇ2; 5'-AMP-activated protein kinase subunit beta-2; AMPK subunit beta-2; PRKAB2
Description
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PRKAB2 protein structure - BS8607 shown in red.