Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB3595 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3595, RRID:AB_1575201
- Product name
- GJA8 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of GJA8.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references A missense mutation in the human connexin50 gene (GJA8) underlies autosomal dominant "zonular pulverulent" cataract, on chromosome 1q.
The human lens intrinsic membrane protein MP70 (Cx50) gene: clonal analysis and chromosome mapping.
The human lens intrinsic membrane protein MP70 (Cx50) gene: clonal analysis and chromosome mapping.
Shiels A, Mackay D, Ionides A, Berry V, Moore A, Bhattacharya S
American journal of human genetics 1998 Mar;62(3):526-32
American journal of human genetics 1998 Mar;62(3):526-32
The human lens intrinsic membrane protein MP70 (Cx50) gene: clonal analysis and chromosome mapping.
Church RL, Wang JH, Steele E
Current eye research 1995 Oct;14(10):979-81
Current eye research 1995 Oct;14(10):979-81
The human lens intrinsic membrane protein MP70 (Cx50) gene: clonal analysis and chromosome mapping.
Church RL, Wang JH, Steele E
Current eye research 1995 Mar;14(3):215-21
Current eye research 1995 Mar;14(3):215-21
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of mouse kidney tissue lysate (35 ug/lane) with GJA8 polyclonal antibody (Cat # PAB3595).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with GJA8 polyclonal antibody (Cat # PAB3595) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)