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- References [9]
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- Product number
- 14157-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14157-1-AP, RRID:AB_2195472
- Product name
- KRAP/SSFA2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated KRAP/SSFA2 antibody (Cat. #14157-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Loss-of-Function SSFA2 Variants Disrupt Fertility Through Impaired Acrosome Formation and Sperm Function.
A sustained calcium response mediated by IP3 receptor anchoring to the desmosome is essential for apoptotic cell elimination.
KRAP regulates mitochondrial Ca2+ uptake by licensing IP3 receptor activity and stabilizing ER-mitochondrial junctions.
Identification of a novel cuproptosis-related gene signature and integrative analyses in patients with lower-grade gliomas.
A loss-of-function variant in SSFA2 causes male infertility with globozoospermia and failed oocyte activation.
CREB regulates the expression of type 1 inositol 1,4,5-trisphosphate receptors.
KRAP tethers IP(3) receptors to actin and licenses them to evoke cytosolic Ca(2+) signals.
Relationship between phosphorylation of sperm-specific antigen and prognosis of lung adenocarcinoma.
Vimentin and the K-Ras-induced actin-binding protein control inositol-(1,4,5)-trisphosphate receptor redistribution during MDCK cell differentiation.
Chen X, Zhang X, Zheng Y, Ling W, Shan X, Wei Y, Jiang T, Zhang Y, Zhang J, Wu S, Feng Y, Zeng X, Zhu Y, Lu F, Zhu X, Li B, Xu W
Andrology 2026 Mar 9;
Andrology 2026 Mar 9;
A sustained calcium response mediated by IP3 receptor anchoring to the desmosome is essential for apoptotic cell elimination.
Cho Y, Koyama-Honda I, Tanimura A, Matsuzawa K, Ikenouchi J
Current biology : CB 2024 Oct 21;34(20):4835-4844.e4
Current biology : CB 2024 Oct 21;34(20):4835-4844.e4
KRAP regulates mitochondrial Ca2+ uptake by licensing IP3 receptor activity and stabilizing ER-mitochondrial junctions.
Atakpa-Adaji P, Ivanova A, Kujawa K, Taylor CW
Journal of cell science 2024 Jun 15;137(12)
Journal of cell science 2024 Jun 15;137(12)
Identification of a novel cuproptosis-related gene signature and integrative analyses in patients with lower-grade gliomas.
Bao JH, Lu WC, Duan H, Ye YQ, Li JB, Liao WT, Li YC, Sun YP
Frontiers in immunology 2022;13:933973
Frontiers in immunology 2022;13:933973
A loss-of-function variant in SSFA2 causes male infertility with globozoospermia and failed oocyte activation.
Huang G, Zhang X, Yao G, Huang L, Wu S, Li X, Guo J, Wen Y, Wang Y, Shang L, Li N, Xu W
Reproductive biology and endocrinology : RB&E 2022 Jul 14;20(1):103
Reproductive biology and endocrinology : RB&E 2022 Jul 14;20(1):103
CREB regulates the expression of type 1 inositol 1,4,5-trisphosphate receptors.
Arige V, Terry LE, Malik S, Knebel TR, Wagner Ii LE, Yule DI
Journal of cell science 2021 Oct 15;134(20)
Journal of cell science 2021 Oct 15;134(20)
KRAP tethers IP(3) receptors to actin and licenses them to evoke cytosolic Ca(2+) signals.
Thillaiappan NB, Smith HA, Atakpa-Adaji P, Taylor CW
Nature communications 2021 Jul 23;12(1):4514
Nature communications 2021 Jul 23;12(1):4514
Relationship between phosphorylation of sperm-specific antigen and prognosis of lung adenocarcinoma.
Okayama A, Kimura Y, Miyagi Y, Oshima T, Oshita F, Ito H, Nakayama H, Nagashima T, Rino Y, Masuda M, Ryo A, Hirano H
Journal of proteomics 2016 Apr 29;139:60-6
Journal of proteomics 2016 Apr 29;139:60-6
Vimentin and the K-Ras-induced actin-binding protein control inositol-(1,4,5)-trisphosphate receptor redistribution during MDCK cell differentiation.
Dingli F, Parys JB, Loew D, Saule S, Mery L
Journal of cell science 2012 Nov 15;125(Pt 22):5428-40
Journal of cell science 2012 Nov 15;125(Pt 22):5428-40
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The KRAP, SSFA2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human KRAP, SSFA2. This antibody recognizes human, rat antigen. The KRAP, SSFA2 antibody has been validated for the following applications: ELISA, WB analysis.
