Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 21641-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21641-1-AP, RRID:AB_10733649
- Product name
- AKT3 antibody
- Antibody type
- Polyclonal
- Description
- AKT3 antibody (Cat. #21641-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mechanism through which the hsa-circ_0000992- hsa- miR- 936-AKT3 regulatory network promotes the PM(2.5)-induced inflammatory response in human bronchial epithelial cells.
circHIPK3 regulates cell proliferation and migration by sponging microRNA-124 and regulating serine/threonine kinase 3 expression in esophageal squamous cell carcinoma.
Effects of CDKN2B-AS1 on cellular proliferation, invasion and AKT3 expression are attenuated by miR-424-5p in a model of ovarian endometriosis.
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Alterations of DNA methylation were associated with the rapid growth of cortisol-producing adrenocortical adenoma during pregnancy.
NEK7 promotes gastric cancer progression as a cell proliferation regulator.
Long Non-coding RNA AK025387 Promotes Cell Migration and Invasion of Gastric Cancer.
EGR1 interacts with DNMT3L to inhibit the transcription of miR-195 and plays an anti-apoptotic role in the development of gastric cancer.
MiR-384 inhibits the proliferation of colorectal cancer by targeting AKT3.
Role of BMI1 in epithelial ovarian cancer: investigated via the CRISPR/Cas9 system and RNA sequencing.
MYO6 knockdown inhibits the growth and induces the apoptosis of prostate cancer cells by decreasing the phosphorylation of ERK1/2 and PRAS40.
MicroRNA-150 negatively regulates the function of CD4(+) T cells through AKT3/Bim signaling pathway.
Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways.
Li JL, Tan Y, Wang QL, Li CX, Hong JC, Wang HJ, Wu Y, Ni C, Peng XW
Ecotoxicology and environmental safety 2024 Jan 15;270:115778
Ecotoxicology and environmental safety 2024 Jan 15;270:115778
circHIPK3 regulates cell proliferation and migration by sponging microRNA-124 and regulating serine/threonine kinase 3 expression in esophageal squamous cell carcinoma.
Yao D, Lin S, Chen S, Wang Z
Bioengineered 2022 Apr;13(4):9767-9780
Bioengineered 2022 Apr;13(4):9767-9780
Effects of CDKN2B-AS1 on cellular proliferation, invasion and AKT3 expression are attenuated by miR-424-5p in a model of ovarian endometriosis.
Wang S, Yi M, Zhang X, Zhang T, Jiang L, Cao L, Zhou Y, Fang X
Reproductive biomedicine online 2021 Jun;42(6):1057-1066
Reproductive biomedicine online 2021 Jun;42(6):1057-1066
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Luo X, Cao M, Gao F, He X
Experimental hematology & oncology 2021 Jun 4;10(1):35
Experimental hematology & oncology 2021 Jun 4;10(1):35
Alterations of DNA methylation were associated with the rapid growth of cortisol-producing adrenocortical adenoma during pregnancy.
Wang C, Sun Y, Yin X, Feng R, Feng R, Xu M, Liang K, Zhao R, Gu G, Jiang X, Su P, Zhang X, Liu J
Clinical epigenetics 2021 Dec 4;13(1):213
Clinical epigenetics 2021 Dec 4;13(1):213
NEK7 promotes gastric cancer progression as a cell proliferation regulator.
Li YK, Zhu XR, Zhan Y, Yuan WZ, Jin WL
Cancer cell international 2021 Aug 21;21(1):438
Cancer cell international 2021 Aug 21;21(1):438
Long Non-coding RNA AK025387 Promotes Cell Migration and Invasion of Gastric Cancer.
Sun YY, Zhang H, Ma RR, Zhang GH, Tian YR, Liu L, Liu L, Gao P
Frontiers in oncology 2020;10:633
Frontiers in oncology 2020;10:633
EGR1 interacts with DNMT3L to inhibit the transcription of miR-195 and plays an anti-apoptotic role in the development of gastric cancer.
Yang Y, Wu F, Zhang J, Sun R, Li F, Li Y, Chang S, Wang L, Wang X, Liu L, Huang C
Journal of cellular and molecular medicine 2019 Nov;23(11):7372-7381
Journal of cellular and molecular medicine 2019 Nov;23(11):7372-7381
MiR-384 inhibits the proliferation of colorectal cancer by targeting AKT3.
Wang YX, Zhu HF, Zhang ZY, Ren F, Hu YH
Cancer cell international 2018;18:124
Cancer cell international 2018;18:124
Role of BMI1 in epithelial ovarian cancer: investigated via the CRISPR/Cas9 system and RNA sequencing.
Zhao Q, Qian Q, Cao D, Yang J, Gui T, Shen K
Journal of ovarian research 2018 Apr 23;11(1):31
Journal of ovarian research 2018 Apr 23;11(1):31
MYO6 knockdown inhibits the growth and induces the apoptosis of prostate cancer cells by decreasing the phosphorylation of ERK1/2 and PRAS40.
Wang D, Zhu L, Liao M, Zeng T, Zhuo W, Yang S, Wu W
Oncology reports 2016 Sep;36(3):1285-92
Oncology reports 2016 Sep;36(3):1285-92
MicroRNA-150 negatively regulates the function of CD4(+) T cells through AKT3/Bim signaling pathway.
Sang W, Sun C, Zhang C, Zhang D, Wang Y, Xu L, Zhang Z, Wei X, Pan B, Yan D, Zhu F, Yan Z, Cao J, Loughran TP Jr, Xu K
Cellular immunology 2016 Aug-Sep;306-307:35-40
Cellular immunology 2016 Aug-Sep;306-307:35-40
Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways.
Liu J, Huang W, Ren C, Wen Q, Liu W, Yang X, Wang L, Zhu B, Zeng L, Feng X, Zhang C, Chen H, Jia W, Zhang L, Xia X, Chen Y
Scientific reports 2015 Jul 24;5:11614
Scientific reports 2015 Jul 24;5:11614
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 21641-1-AP(AKT3 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AKT3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human AKT3. This antibody recognizes human,mouse,rat,zebrafish antigen. The AKT3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.