abx010372

antibody from Abbexa

Targeting: AKT3 PKBG, PRKBG, RAC-gamma

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

abx010372

Provider

Abbexa

Product name

RAC-Gamma Serine/threonine-Protein Kinase (Akt3) Antibody

Antibody type

Monoclonal

Description

Akt3 (also designated protein kinase B gamma or v-akt murine thymoma viral oncogene homolog 3), with 479-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt2. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake.Akt3 is not required for the maintenance of normal carbohydrate metabolism but is essential for the attainment of normal organ size. Identifying Akt3 as a selective target in melanoma cells also provides new therapeutic opportunities for patients in the advanced stages of this disease.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.