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- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Immunocytochemistry [2]
- Immunohistochemistry [4]
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- Product number
- PA5-64232 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Ferroportin Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant protein fragment
- Description
- Immunogen sequence: VKAGLKEEET ELKQLNLHKD TEPKPLEGTH LMGVKDSNIH ELEHEQEPTC ASQMAEPFRT FRDGWVSYYN Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 86%.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.40 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein.
The Ferroxidase Hephaestin in Lung Cancer: Pathological Significance and Prognostic Value.
Sterling JK, Kam TI, Guttha S, Park H, Baumann B, Mehrabani-Tabari AA, Schultz H, Anderson B, Alnemri A, Chou SC, Troncoso JC, Dawson VL, Dawson TM, Dunaief JL
Cell reports 2022 Feb 15;38(7):110358
Cell reports 2022 Feb 15;38(7):110358
The Ferroxidase Hephaestin in Lung Cancer: Pathological Significance and Prognostic Value.
Zacchi P, Belmonte B, Mangogna A, Morello G, Scola L, Martorana A, Borelli V
Frontiers in oncology 2021;11:638856
Frontiers in oncology 2021;11:638856
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of SLC40A1 in human cell line U-2 OS using a SLC40A1 Polyclonal Antibody (Product # PA5-64232) shows localization to plasma membrane and cytosol.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of SLC40A1 in human cell line U-2 OS using a SLC40A1 Polyclonal Antibody (Product # PA5-64232) shows localization to plasma membrane and cytosol.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of Ferroportin in human placenta using Ferroportin Polyclonal Antibody (Product # PA5-64232) shows weak to moderate positivity in erythrocytes.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of Ferroportin in human duodenum using Ferroportin Polyclonal Antibody (Product # PA5-64232) shows weak cytoplasmic positivity in glandular cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of Ferroportin in human spleen using Ferroportin Polyclonal Antibody (Product # PA5-64232) shows weak to moderate cytoplasmic positivity in cells in red pulp.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of Ferroportin in human pancreas using Ferroportin Polyclonal Antibody (Product # PA5-64232) shows no cytoplasmic positivity in exocrine glandular cells as expected.
