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- Antibody Data
- Antigen structure
- References [174]
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- Product number
- 26601-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- SLC40A1/FPN1 antibody
- Antibody type
- Polyclonal
- Description
- SLC40A1/FPN1 antibody (Cat. #26601-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Transcription factor EGR1 orchestrates ferroptosis to mitigate sepsis-induced myocardial injury by enhancing ferroportin expression.
Cysteine imaging reveals early redox dysregulation and identifies gnetol as a ferroptosis-modulating agent in doxorubicin cardiotoxicity.
Blue LED light induces dry eye disease via NCOA4-mediated ferritinophagy and iron-overload.
Targeting the OXNAD1-PTGS2 axis with resveratrol overcomes ferroptosis Inhibition and reverses 5-FU resistance in gastric cancer.
In situ delivery of JPH203 via camptothecin-peptide conjugate nanoassemblies to trigger ferroptosis in triple-negative breast cancer.
c-MAF Transcriptionally Activates Slc40a1 to Repress Ferroptosis in Sepsis-Associated Encephalopathy.
Dietary advanced glycation products combined with chronic restraint stress induced anxiety-like and depression-like behaviors in male mice.
Disruption of iron homeostasis by HERC2-FTL axis leads to chondrocyte loss and exacerbates osteoarthritis.
Ginsenoside Rh4 Triggers Ferroptosis in Lung Cancer: Targeting KEAP1/NRF2/HO-1 and Remodeling Gut Microbiota for Butyrate-Mediated ATF3 Activation.
Dihuang Yinzi Ameliorates Cognitive Impairments and Inhibits Ferroptosis in APP/PS1 Mice.
Shunaoxin dropping pills alleviate cerebral ischemia-reperfusion injury in MCAO rats associated with ferroptosis inhibition and AKT/Nrf2/HO-1 pathway activation.
Loss of cGAS facilitates angiogenesis in diabetic foot ulcer healing by suppressing the STING/ferroptosis pathway.
CDKN3 promoted triple-negative breast cancer by inhibiting ferroptosis through the upregulation of HSP90.
Polystyrene nanoparticles induced adverse pregnancy outcomes via the activation of placental ferroptosis and gut microbiota dysfunction.
SARS-CoV-2 Spike Protein Induces Time-Dependent and Brain-Region-Specific Alterations in Ferroptosis Markers: A Preliminary Study in K18-hACE2 Mice.
Increased levels of systemic iron content in adult-onset interleukin-6 knockout mice.
Electroacupuncture regulates neuronal ferroptosis and ferritinophagy through lysosomal-mediated TFEB activation in cerebral ischemia-reperfusion.
Peritumoural adipose tissue promotes ferroptosis resistance by 3-hydroxykynurenine-mediated suppression of ferritinophagy.
Molecular mechanism of testicular oxidative stress-induced ferroptosis in Leydig cells caused by cryptorchidism in yak.
Altered Iron Regulation and the Role of Ferritin Heavy Chain in Dermatomyositis Patients.
SLC40A1-mediated positive feedback loop with M1 macrophages suppresses epithelial ovarian cancer progression.
Targeted ferroptosis of myofibroblasts by tubeimoside I attenuates hypertrophic scar formation.
Neuroprotective effects of ethanol extraction from Rubia yunnanensis Diels on chronic cerebral hypoperfusion: modulation of the System Xc-/GSH/GPX4 axis to alleviate oxidative stress and ferroptosis.
Yersiniabactin produced by Escherichia coli promotes intestinal inflammation through lipid peroxidation and ferroptosis.
Targeting GJB4 to inhibit tumor growth and induce ferroptosis in pancreatic cancer.
Histone lactylation exacerbates acute lung injury in septic mice by promoting ferroptosis in pulmonary microvascular endothelial cells.
Oxidative stress activates YAP/TEAD1/NCOA4 axis to promote ferroptosis of endplate chondrocytes and aggravate intervertebral disc degeneration.
Atp7a deficiency induces axonal and myelin developmental defects in zebrafish via ferroptosis.
Unraveling the molecular mechanisms of paraquat toxicity: The interplay of ATF4, ferroptosis, and endoplasmic reticulum stress.
Iron overload exaggerates renal ischemia-reperfusion injury by promoting tubular cuproptosis via interrupting function of LIAS.
Reprogramming Iron Metabolism via the RIG-I/c-Myc/FTH Axis Mitigates Renal Ischemia-Reperfusion Injury.
The long noncoding RNA SNHG12 defines KEAP1 stability and ferroptosis susceptibility by targeting E3 ligase TRIM25.
Dapagliflozin improves diabetic nephropathy by regulating autophagy and ferroptosis through CYP450s/ROS pathway.
Ferredoxin 1-like maintains iron homeostasis and hepatoma cell survival.
Chidamide impedes glycolysis but increases ferroptosis and cisplatin sensitivity of lung cancer cells through downregulating USP35.
Epigenetic suppression of Nrf2-Slc40a1 axis induces ferroptosis and enhances immunotherapy in pancreatic cancer.
Muscone inhibits ferroptosis for neuroprotection in a Parkinson's disease model.
Manganese stimulates ferroptosis to trigger neurotoxicity in mice and HT22 cells: the role of NCOA4-mediated ferritinophagy.
Gambogic acid induces ferroptosis and suppresses colorectal cancer progression by modulating the m6A modification of p62.
From Wild Vegetable to Renal Protector: The Therapeutic Potential of Aralia elata (Miq.) Seem.
Dexmedetomidine alleviates ferroptosis caused by traumatic brain injury via the NRF2/HO-1/GPX4 pathway.
Hepatocyte growth factor alleviates alcoholic cardiomyopathy through the Nrf2 pathway-a focus on iron metabolism.
SLC11A2 affects nutritional immunity in the gut epithelium.
Targeting PIM1 by Bruceine D attenuates skin fibrosis via myofibroblast ferroptosis.
The ferroptosis of sertoli cells inducing blood-testis barrier damage is produced by oxidative stress in cryptorchidism.
Heterogeneity of fibroblasts from different anatomical sites in healthy human knee ligaments revealed by single-cell RNA sequencing.
Infectious Spleen and Kidney Necrosis Virus Triggers Ferroptosis in CPB Cells to Enhance Virus Replication.
Inhibition of Phosphodiesterase 4 Suppresses Neuronal Ferroptosis After Cerebral Ischemia/Reperfusion.
The molecular mechanism by which CTSB degrades FPN to disrupt macrophage iron homeostasis and promote the progression of atherosclerosis.
5-HT(7)R Deficiency Alleviates ADP-Heptose-Induced Cognitive Impairment via Inhibiting Ferroptosis and Neuroinflammation in Mice.
OTUB1-SLC7A11 Axis Mediates 4-Octyl Itaconate Protection Against Acetaminophen-Induced Ferroptotic Liver Injury.
Sevoflurane exposure triggers ferroptosis of neuronal cells initiated by the activation of ATM/p53 in the neonatal mouse brain via JNK/p38 MAPK-mediated oxidative DNA damage.
Eburicoic acid inhibits endothelial cell pyroptosis and retards the development of atherosclerosis through the Keap1/Nrf2/HO‑1/ROS pathway.
Metabolism and Mendelian randomization study on the mechanism of Buyang Huanwu Decoction in regulating iron metabolism and improving cerebral ischemia-reperfusion injury.
(+)-JQ-1 alleviates cardiac injury in myocardial infarction by inhibiting ferroptosis through the NAMPT/SIRT1 pathway.
Low doses of ozone alleviate cardiomyocyte ferroptosis induced by hypoxia-reoxygenation injury via the AMPK-mTOR pathway.
Viruses hijack FPN1 to disrupt iron withholding and suppress host defense.
ACSS2 protects against alcohol-induced hepatocyte ferroptosis through regulation of hepcidin expression.
Moderate static magnetic field regulates iron metabolism and salvage bone loss caused by iron accumulation.
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis.
Prolonged tamoxifen treatment induces iron deposition and ferroptosis in the liver.
Testosterone deficiency aggravates diet-induced non-alcoholic fatty liver disease by inducing hepatocyte ferroptosis via targeting BMAL1 in mice.
The GPR30-Mediated BMP-6/HEP/FPN Signaling Pathway Inhibits Ferroptosis in Bone Marrow Mesenchymal Stem Cells to Alleviate Osteoporosis.
Targeted temperature management alleviates post-resuscitation myocardial dysfunction by inhibiting ferroptosis.
Metallothionein 2A alleviates ulcerative colitis by inhibiting ferroptosis in intestinal epithelial cells with Tfrc downregulation.
The phytochemical arbutin exerts potent anti-Toxoplasma effects through activation of cell-autonomous defense mechanisms while attenuating inflammation.
Fer-1 alleviates traumatic brain injury-induced cognitive impairment by inhibiting hippocampal ferroptosis.
Nicotinamide Mononucleotide Alleviates the Development of Fibrotic Cataract by Modulating the Nrf2/FPN1 Signaling Pathway.
Deciphering the molecular landscape of NMDAR-E associated ovarian teratomas: a Multi-Omics approach.
Adipocytes orchestrate obesity-related chronic inflammation through β2-microglobulin.
Toxoplasma gondii-induced ferroptosis contributes to acute lung injury in mice.
Nicotinamide riboside alleviates sepsis-induced acute kidney injury by suppressing ferroptosis.
Baicalein attenuates metabolic dysfunction-associated steatohepatitis by regulating macrophage ferroptosis through nuclear factor (erythroid-derived 2)-like 2 pathway.
Ferroptosis contributed to endoplasmic reticulum stress in preterm birth by targeting LHX1 and IRE-1.
Trimethylamine N-oxide Induced Chronic Kidney Injury by Triggering PANoptosis.
Effect of Self-Assembled Polydopamine Nanoparticles on Ferroptosis in an MPTP-Induced Parkinson's Disease Mice Model.
Quercetin alleviates LPS/iE-DAP-induced liver injury by suppressing ferroptosis via regulating ferritinophagy and intracellular iron efflux.
Stress-mediated Activation of Ferroptosis, Pyroptosis, and Apoptosis Following Mild Traumatic Brain Injury Exacerbates Neurological Dysfunctions.
Targeted sonodynamic therapy induces tumor cell quasi-immunogenic ferroptosis and macrophage immunostimulatory autophagy in glioblastoma.
Amino-modified IONPs potentiates ferroptotic cell death due to the release of Fe ion in the lysosome.
Dapagliflozin alleviates high-fat-induced obesity cardiomyopathy by inhibiting ferroptosis.
Short-term effects of subacute ruminal acidosis on ferroptosis and iron metabolism in the livers of lactating sheep fed a high-grain diet.
Integrative insights into the role of CAV1 in ketogenic diet and ferroptosis in pancreatic cancer.
Saponins from Astragalus membranaceus (Fisch.) Bge Alleviated Neuronal Ferroptosis in Alzheimer's Disease by Regulating the NOX4/Nrf2 Signaling Pathway.
Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis.
Progressive iron overload in middle-aged mice impairs olfactory function, triggers lipid oxidation and induces apoptosis.
Effect of ferric citrate on hippocampal iron accumulation and widespread molecular alterations associated with cognitive disorder in an ovariectomized mice model.
Daphnetin induces ferroptosis in ovarian cancer by inhibiting NAD(P)H:Quinone oxidoreductase 1 (NQO1).
MMP9 drives ferroptosis by regulating GPX4 and iron signaling.
Ellagic acid ameliorates arsenic-induced neuronal ferroptosis and cognitive impairment via Nrf2/GPX4 signaling pathway.
The hepcidin-ferroportin axis influences mitochondrial function, proliferation, and migration in pulmonary artery endothelial and smooth muscle cells.
DHA and EPA alleviate depressive-like behaviors in chronic sleep-deprived mice: Involvement of iron metabolism, oligodendrocyte-lipids peroxidation and the LCN2-NLRP3 signaling axis.
Trimethylamine Induced Chronic Kidney Injury by Activating the ZBP1-NLRP3 Inflammasome Pathway.
Water extract of moschus alleviates erastin-induced ferroptosis by regulating the Keap1/Nrf2 pathway in HT22 cells.
Therapeutic potential and mechanisms of Rifaximin in ameliorating iron overload-induced ferroptosis and liver fibrosis in vivo and in vitro.
Mitochondrial ferritin alleviates ferroptosis in a kainic acid-induced mouse epilepsy model by regulating iron homeostasis: Involvement of nuclear factor erythroid 2-related factor 2.
Hinokitiol protects gastric injury from ethanol exposure via its iron sequestration capacity.
Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx.
Effects of chronic low-level lead (Pb) exposure on cognitive function and hippocampal neuronal ferroptosis: An integrative approach using bioinformatics analysis, machine learning, and experimental validation.
NCOA4-mediated ferritinophagy participates in cadmium-triggered ferroptosis in spermatogonia.
Nicorandil Regulates Ferroptosis and Mitigates Septic Cardiomyopathy via TLR4/SLC7A11 Signaling Pathway.
YTHDF2 Promotes Cardiac Ferroptosis via Degradation of SLC7A11 in Cardiac Ischemia-Reperfusion Injury.
Mitochondrial GCN5L1 acts as a novel regulator for iron homeostasis to promote sorafenib sensitivity in hepatocellular carcinoma.
Rocaglamide regulates iron homeostasis by suppressing hepcidin expression.
Targeting PKD2 aggravates ferritinophagy-mediated ferroptosis via promoting autophagosome-lysosome fusion and enhances efficacy of carboplatin in lung adenocarcinoma.
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
Gemfibrozil Alleviates Cognitive Impairment by Inhibiting Ferroptosis of Astrocytes via Restoring the Iron Metabolism and Promoting Antioxidant Capacity in Type 2 Diabetes.
Identification of SLC40A1, LCN2, CREB5, and SLC7A11 as ferroptosis-related biomarkers in alopecia areata through machine learning.
Apelin deficiency exacerbates cardiac injury following infarction by accelerating cardiomyocyte ferroptosis.
Exploring the underlying mechanism by transcriptome sequencing in rats with high-voltage electrical burns and the role of iron metabolism.
A 0.2 T-0.4 T Static Magnetic Field Improves the Bone Quality of Mice Subjected to Hindlimb Unloading and Reloading Through the Dual Regulation of BMSCs via Iron Metabolism.
Investigating the potential risk of cadmium exposure on seizure severity and anxiety-like behaviors through the ferroptosis pathway in epileptic mice: An integrated multi-omics approach.
MCM4 potentiates evasion of hepatocellular carcinoma from sorafenib-induced ferroptosis through Nrf2 signaling pathway.
1,3-Dichloro-2-propanol Induced Renal Cell Ferroptosis via the Circadian Clock Protein BMAL1 Targeting GPX4.
MoS(2) Nanosheets at Low Doses Induced Cardiotoxicity in Developing Zebrafish via Ferroptosis: Influence of Lateral Size and Surface Modification.
Social defeat stress impairs systemic iron metabolism by activating the hepcidin-ferroportin axis.
Preventive effects of lactoferrin on acute alcohol-induced liver injury via iron chelation and regulation of iron metabolism.
Hepcidin depending on astrocytic NEO1 ameliorates blood-brain barrier dysfunction after subarachnoid hemorrhage.
Magnetically attracting hydrogel reshapes iron metabolism for tissue repair.
Inhibiting DNA methyltransferase DNMT3B confers protection against ferroptosis in nucleus pulposus and ameliorates intervertebral disc degeneration via upregulating SLC40A1.
Human umbilical cord mesenchymal stem cells alleviate chemotherapy-induced premature ovarian insufficiency mouse model by suppressing ferritinophagy-mediated ferroptosis in granulosa cells.
Excess iron accumulation mediated senescence in diabetic kidney injury.
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Non-targeted metabolomics strategy reveals the role of Geng-Nian-Shu in regulating ferroptosis in perimenopausal syndrome.
Role of ferroptosis in hypoxic preconditioning to reduce propofol neurotoxicity.
Moderate Intensity of Treadmill Exercise Rescues TBI-Induced Ferroptosis, Neurodegeneration, and Cognitive Impairments via Suppressing STING Pathway.
Trastuzumab-induced cardiomyopathy via ferroptosis-mediated mitochondrial dysfunction.
PPM1K mediates metabolic disorder of branched-chain amino acid and regulates cerebral ischemia-reperfusion injury by activating ferroptosis in neurons.
Blocked erythroid differentiation and delayed enucleation of erythroblasts may contribute to murine embryonic toxicity upon exposure to low dose of cadmium.
Resveratrol inhibits ferroptosis via activating NRF2/GPX4 pathway in mice with spinal cord injury.
Enriched environment attenuates ferroptosis after cerebral ischemia/reperfusion injury by regulating iron metabolism.
Neuroprotective Effect of Hydrogen Sulfide Subchronic Treatment Against TBI-Induced Ferroptosis and Cognitive Deficits Mediated Through Wnt Signaling Pathway.
Hepcidin as a key regulator of iron homeostasis triggers inflammatory features in the normal endometrium.
Quercetin alleviates subarachnoid hemorrhage-induced early brain injury via inhibiting ferroptosis in the rat model.
Thorium(IV) triggers ferroptosis through disrupting iron homeostasis and heme metabolism in the liver following oral ingestion.
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA4.
Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3-NFS1 axis in doxorubicin-induced cardiotoxicity.
Super-enhancer-driven MLX mediates redox balance maintenance via SLC7A11 in osteosarcoma.
cGAS-STING pathway aggravates early cerebral ischemia-reperfusion injury in mice by activating NCOA4-mediated ferritinophagy.
TrkB agonist N-acetyl serotonin promotes functional recovery after traumatic brain injury by suppressing ferroptosis via the PI3K/Akt/Nrf2/Ferritin H pathway.
Sphingosine 1-phosphate alleviates radiation-induced ferroptosis in ovarian granulosa cells by upregulating glutathione peroxidase 4.
Organic extracts in PM2.5 are the major triggers to induce ferroptosis in SH-SY5Y cells.
Human hematopoietic stem cell vulnerability to ferroptosis.
Guilu-Erxian-Glue alleviates Tripterygium wilfordii polyglycoside-induced oligoasthenospermia in rats by resisting ferroptosis via the Keap1/Nrf2/GPX4 signaling pathway.
Sculponeatin A promotes the ETS1-SYVN1 interaction to induce SLC7A11/xCT-dependent ferroptosis in breast cancer.
IRP1 mediated ferroptosis reverses temozolomide resistance in glioblastoma via affecting LCN2/FPN1 signaling axis depended on NFKB2.
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
Iron-frataxin involved in the protective effect of quercetin against alcohol-induced liver mitochondrial dysfunction.
Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats.
Low Level of Dietary Organic Trace Elements Improve the Eggshell Strength, Trace Element Utilization, and Intestinal Function in Late-Phase Laying Hens.
Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury.
HO-1 Contributes to Luteolin-Triggered Ferroptosis in Clear Cell Renal Cell Carcinoma via Increasing the Labile Iron Pool and Promoting Lipid Peroxidation.
NCOA4-mediated ferritinophagy is involved in ionizing radiation-induced ferroptosis of intestinal epithelial cells.
Inhibition of ferroptosis attenuates oligospermia in male Nrf2 knockout mice.
Salidroside Alleviates Renal Fibrosis in SAMP8 Mice by Inhibiting Ferroptosis.
The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages.
Eriodictyol ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via vitamin D receptor-mediated Nrf2 activation.
3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis.
Electroacupuncture Preconditioning Reduces Oxidative Stress in the Acute Phase of Cerebral Ischemia-Reperfusion in Rats by Regulating Iron Metabolism Pathways.
Holo-lactoferrin: the link between ferroptosis and radiotherapy in triple-negative breast cancer.
Deferoxamine Counteracts Cisplatin Resistance in A549 Lung Adenocarcinoma Cells by Increasing Vulnerability to Glutamine Deprivation-Induced Cell Death.
N2L, a novel lipoic acid-niacin dimer, attenuates ferroptosis and decreases lipid peroxidation in HT22 cells.
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Activation of NRF2/FPN1 pathway attenuates myocardial ischemia-reperfusion injury in diabetic rats by regulating iron homeostasis and ferroptosis.
Tolerable upper intake level of iron damages the liver of weaned piglets.
Targeting miR-10a-5p/IL-6R axis for reducing IL-6-induced cartilage cell ferroptosis.
Tolerable upper intake level of iron damages the intestine and alters the intestinal flora in weaned piglets.
miR-30-5p-mediated ferroptosis of trophoblasts is implicated in the pathogenesis of preeclampsia.
The Effects of the Combination of Oral Lactoferrin and Iron Injection on Iron Homestasis, Antioxidative Abilities and Cytokines Activities of Suckling Piglets.
Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome.
Iron Transport from Ferrous Bisglycinate and Ferrous Sulfate in DMT1-Knockout Human Intestinal Caco-2 Cells.
Iron depletion participates in the suppression of cell proliferation induced by lipin1 overexpression.
Jiang S, Song G, Zhu H, Wang X, Pan T, Dai Z
CytoJournal 2026;23:3
CytoJournal 2026;23:3
Cysteine imaging reveals early redox dysregulation and identifies gnetol as a ferroptosis-modulating agent in doxorubicin cardiotoxicity.
Chen Y, Zhang B, Wei Y, Dai Y, Zhang B, Li J, Wu KJ, Sun N, Shao C
Redox biology 2026 May;92:104131
Redox biology 2026 May;92:104131
Blue LED light induces dry eye disease via NCOA4-mediated ferritinophagy and iron-overload.
Yang Q, Li Q, Xia Y, Ge J, Xie Y, Shen C, Chen K, Chen J, Shen Y, Tong J, Zhou H
Ecotoxicology and environmental safety 2026 May;316:120150
Ecotoxicology and environmental safety 2026 May;316:120150
Targeting the OXNAD1-PTGS2 axis with resveratrol overcomes ferroptosis Inhibition and reverses 5-FU resistance in gastric cancer.
Wang J, Xu B, Lin X, Chen B, Liu X, Wu W
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2026 May;29(3):561-577
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2026 May;29(3):561-577
In situ delivery of JPH203 via camptothecin-peptide conjugate nanoassemblies to trigger ferroptosis in triple-negative breast cancer.
Zhang W, Chen L, Dong Y, Zeng Y, Chen Y, Liu Y, Wang J, Shi F
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114829
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114829
Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis
.
Guo Z, Wang J, Wang Y, Liu X, Xia Y, Liu P, Qi L, Liu J, Wang X
Molecular medicine reports 2026 Mar;33(3)
Molecular medicine reports 2026 Mar;33(3)
c-MAF Transcriptionally Activates Slc40a1 to Repress Ferroptosis in Sepsis-Associated Encephalopathy.
Song W, Shen Q, Zhang H, Bu X, Gao W, Wang W
CNS neuroscience & therapeutics 2026 Mar;32(3):e70820
CNS neuroscience & therapeutics 2026 Mar;32(3):e70820
Dietary advanced glycation products combined with chronic restraint stress induced anxiety-like and depression-like behaviors in male mice.
Zhang Y, Gu K, Xin L, Xia Y, Yang G, Cai J, He Z, Qin LQ, Wan Z
NPJ science of food 2026 Mar 8;10(1)
NPJ science of food 2026 Mar 8;10(1)
Disruption of iron homeostasis by HERC2-FTL axis leads to chondrocyte loss and exacerbates osteoarthritis.
Zhong Y, Duan J, Chen Z, Ye W, Cai W, Wu R, Mao X, Dai X, Dou P
Apoptosis : an international journal on programmed cell death 2026 Mar 19;31(3)
Apoptosis : an international journal on programmed cell death 2026 Mar 19;31(3)
Ginsenoside Rh4 Triggers Ferroptosis in Lung Cancer: Targeting KEAP1/NRF2/HO-1 and Remodeling Gut Microbiota for Butyrate-Mediated ATF3 Activation.
Zhu Q, Xu W, Yang G, Gao Y, Zhao Y, Zhao Z, Kang Y, Li S, Zhao L
International journal of molecular sciences 2026 Mar 16;27(6)
International journal of molecular sciences 2026 Mar 16;27(6)
Dihuang Yinzi Ameliorates Cognitive Impairments and Inhibits Ferroptosis in APP/PS1 Mice.
Xie F, Zhou L, Yu M
Biochemical genetics 2026 Jun;64(3):4282-4297
Biochemical genetics 2026 Jun;64(3):4282-4297
Shunaoxin dropping pills alleviate cerebral ischemia-reperfusion injury in MCAO rats associated with ferroptosis inhibition and AKT/Nrf2/HO-1 pathway activation.
Guo Y, Cheng X, Song Y, Li D, Deng H, Qin X, Hao H, Han Y, Xu W, Zhao L, Xu S
Fitoterapia 2026 Jun;191:107245
Fitoterapia 2026 Jun;191:107245
Loss of cGAS facilitates angiogenesis in diabetic foot ulcer healing by suppressing the STING/ferroptosis pathway.
Li W, Kang M, Zhang G, Hu H, Qin H
International immunopharmacology 2026 Jul 1;180:116684
International immunopharmacology 2026 Jul 1;180:116684
CDKN3 promoted triple-negative breast cancer by inhibiting ferroptosis through the upregulation of HSP90.
Zhao Q, Wang Y
Toxicology and applied pharmacology 2026 Jan;506:117629
Toxicology and applied pharmacology 2026 Jan;506:117629
Polystyrene nanoparticles induced adverse pregnancy outcomes via the activation of placental ferroptosis and gut microbiota dysfunction.
He Z, Cai J, Liu R, Yan W, Yang G, Yu R, Xin L, Wan Z
Reproductive toxicology (Elmsford, N.Y.) 2026 Jan;139:109113
Reproductive toxicology (Elmsford, N.Y.) 2026 Jan;139:109113
SARS-CoV-2 Spike Protein Induces Time-Dependent and Brain-Region-Specific Alterations in Ferroptosis Markers: A Preliminary Study in K18-hACE2 Mice.
Yehia A, Toufaily C, Abdel Ghaffar DM, El Wakeel G, Adel M, Mostafa AF, Abulseoud OA
International journal of molecular sciences 2026 Feb 4;27(3)
International journal of molecular sciences 2026 Feb 4;27(3)
Increased levels of systemic iron content in adult-onset interleukin-6 knockout mice.
Zhang F, Zhang C, Luo Q, Li J, Qiu X, Qian Z
Redox report : communications in free radical research 2026 Dec;31(1):2602306
Redox report : communications in free radical research 2026 Dec;31(1):2602306
Electroacupuncture regulates neuronal ferroptosis and ferritinophagy through lysosomal-mediated TFEB activation in cerebral ischemia-reperfusion.
Tang B, Xu X, Zhao W, Zhou Q, Du G, Wang H
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 Apr;46(4):963-975
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 Apr;46(4):963-975
Peritumoural adipose tissue promotes ferroptosis resistance by 3-hydroxykynurenine-mediated suppression of ferritinophagy.
Zhang YY, Han Y, Tan YT, Lu YX, Ma MY, Zheng YQ, Chen HJ, Fu HY, Mo HY, Wu QN, Luo XJ, Liao K, Chen WQ, Zeng ZL, Piao HL, Du HL, Lin JZ, Tian T, Xu RH, Ju HQ
Nature cell biology 2026 Apr;28(4):783-796
Nature cell biology 2026 Apr;28(4):783-796
Molecular mechanism of testicular oxidative stress-induced ferroptosis in Leydig cells caused by cryptorchidism in yak.
Zeng J, Yuan L, Qi Y, Chen G, Chen Y, Li H, Song Y, Zhang Y
Theriogenology 2026 Apr 15;261:117946
Theriogenology 2026 Apr 15;261:117946
Altered Iron Regulation and the Role of Ferritin Heavy Chain in Dermatomyositis Patients.
Li Q, Cheng X, Zhou M, Ji N, Zhu S, Jiang J, Fang Q, Liu M
Journal of inflammation research 2025;18:14697-14707
Journal of inflammation research 2025;18:14697-14707
SLC40A1-mediated positive feedback loop with M1 macrophages suppresses epithelial ovarian cancer progression.
Wang G, Huang S, Yin B, Shangguan F, Ma J, Li A, Xia Z, Xu Z, Li Y, Jin H, Hu Y, Huang B
Frontiers in immunology 2025;16:1709597
Frontiers in immunology 2025;16:1709597
Targeted ferroptosis of myofibroblasts by tubeimoside I attenuates hypertrophic scar formation.
Wang J, Wang C, Jia Y, Chen F, Wang Y, Du J
Frontiers in pharmacology 2025;16:1654108
Frontiers in pharmacology 2025;16:1654108
Neuroprotective effects of ethanol extraction from Rubia yunnanensis Diels on chronic cerebral hypoperfusion: modulation of the System Xc-/GSH/GPX4 axis to alleviate oxidative stress and ferroptosis.
Cheng J, Ma X, Tao J, Jiang X, Chen P, Duan X
Frontiers in pharmacology 2025;16:1552228
Frontiers in pharmacology 2025;16:1552228
Yersiniabactin produced by Escherichia coli promotes intestinal inflammation through lipid peroxidation and ferroptosis.
Wang H, Chen B, Xiao P, Han D, Gao B, Yan Y, Zhao R, Pan T, Zhang J, Zhou M, Lv L, Gao H
Frontiers in microbiology 2025;16:1542801
Frontiers in microbiology 2025;16:1542801
Targeting GJB4 to inhibit tumor growth and induce ferroptosis in pancreatic cancer.
Zheng X, Li W, Li X, Yao Q, Zheng L, Fan R, Bie P
Frontiers in oncology 2025;15:1585236
Frontiers in oncology 2025;15:1585236
Histone lactylation exacerbates acute lung injury in septic mice by promoting ferroptosis in pulmonary microvascular endothelial cells.
Fang P, Li S, Lu ZQ, Xia DL, Xu MM, Pan JJ, Fu L, Sun GY, You QH
Burns & trauma 2025;13:tkaf056
Burns & trauma 2025;13:tkaf056
Oxidative stress activates YAP/TEAD1/NCOA4 axis to promote ferroptosis of endplate chondrocytes and aggravate intervertebral disc degeneration.
Wang H, Liu X, Jing X, Zhang B, Liu X, Liu X, Jia F, Su C, Wang W, Cui X
Journal of orthopaedic translation 2025 Sep;54:8-25
Journal of orthopaedic translation 2025 Sep;54:8-25
Atp7a deficiency induces axonal and myelin developmental defects in zebrafish via ferroptosis.
Wu Y, Li J, Zhai W, Liu W, Wu H, Liu H, Min J, Wang F, Liu JX
Neurobiology of disease 2025 Sep;213:107027
Neurobiology of disease 2025 Sep;213:107027
Unraveling the molecular mechanisms of paraquat toxicity: The interplay of ATF4, ferroptosis, and endoplasmic reticulum stress.
Ke J, Cai Q, Ge X, Zhang S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115602
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115602
Iron overload exaggerates renal ischemia-reperfusion injury by promoting tubular cuproptosis via interrupting function of LIAS.
Chen S, Chen T, Xu C, Yu X, Shi J, Yang C, Zhu T
Redox biology 2025 Oct;86:103795
Redox biology 2025 Oct;86:103795
Reprogramming Iron Metabolism via the RIG-I/c-Myc/FTH Axis Mitigates Renal Ischemia-Reperfusion Injury.
Zhang Y, Xing J, Yao L, Zou Y, Peng H, Yi X, Bai L, Yu Y, Liu H, Li X, Zhai X
Antioxidants & redox signaling 2025 Oct;43(10-12):622-636
Antioxidants & redox signaling 2025 Oct;43(10-12):622-636
The long noncoding RNA SNHG12 defines KEAP1 stability and ferroptosis susceptibility by targeting E3 ligase TRIM25.
Guo Y, Zhu S, Wu W, Cai Y, Sehgal SA, Huang F, Wu H
The Journal of biological chemistry 2025 Oct;301(10):110689
The Journal of biological chemistry 2025 Oct;301(10):110689
Dapagliflozin improves diabetic nephropathy by regulating autophagy and ferroptosis through CYP450s/ROS pathway.
Liang H, Chen S, Zhong J, Chen X, Xie T, Chen Z, Bai Z, Yuan J, Jiang P, Zhao X, Xiao Y
Biochemical pharmacology 2025 Oct;240:117134
Biochemical pharmacology 2025 Oct;240:117134
Ferredoxin 1-like maintains iron homeostasis and hepatoma cell survival.
Zheng J, Zheng S, Zhou Q, Wu Y, Zhu C, Zheng Y, Li H, Li M, Zhong W, Yan D
Free radical biology & medicine 2025 Oct;238:52-63
Free radical biology & medicine 2025 Oct;238:52-63
Chidamide impedes glycolysis but increases ferroptosis and cisplatin sensitivity of lung cancer cells through downregulating USP35.
Wang K, An L, Zang A, Huo Y
BMC cancer 2025 Oct 3;25(1):1504
BMC cancer 2025 Oct 3;25(1):1504
Epigenetic suppression of Nrf2-Slc40a1 axis induces ferroptosis and enhances immunotherapy in pancreatic cancer.
Zhang Y, Yu R, Li Q, Song S, Fu Y, Shen X, Xu T, Zhang Y, Liang J, Zhang Z, Xu S, Tang J, Zhao Y, Shen C, Zhuang Y, Zhang J, Wang L, Zou X, Chen D, Lv Y, Zhang S
Journal for immunotherapy of cancer 2025 Oct 23;13(10)
Journal for immunotherapy of cancer 2025 Oct 23;13(10)
Muscone inhibits ferroptosis for neuroprotection in a Parkinson's disease model.
Xu M, Zhao L, Xiao F, Zhou C, Ouyang Y, Qu S
Free radical biology & medicine 2025 Nov;239:298-316
Free radical biology & medicine 2025 Nov;239:298-316
Manganese stimulates ferroptosis to trigger neurotoxicity in mice and HT22 cells: the role of NCOA4-mediated ferritinophagy.
Tao Z, Zhang X, Chen J, Hu J, Wang S, Xing G, Ngeng NA, Malik A, Appiah-Kubi K, Farina M, Skalny AV, Tinkov AA, Aschner M, Yang B, Lu R
Neurochemistry international 2025 Nov;190:106065
Neurochemistry international 2025 Nov;190:106065
Gambogic acid induces ferroptosis and suppresses colorectal cancer progression by modulating the m6A modification of p62.
Wang J, Deng J, Sun B, Qiao G, Yang J, Gao Z, Zhang Q, Dong M, Qu P, Wang Z
Cellular signalling 2025 Nov;135:112024
Cellular signalling 2025 Nov;135:112024
From Wild Vegetable to Renal Protector: The Therapeutic Potential of Aralia elata (Miq.) Seem.
Wu J, Liu Y, Xu Z, Tan H, Huang M, Jiang C, He W, Wei M, Du Z, Qiang S
Food science & nutrition 2025 Nov;13(11):e71212
Food science & nutrition 2025 Nov;13(11):e71212
Dexmedetomidine alleviates ferroptosis caused by traumatic brain injury via the NRF2/HO-1/GPX4 pathway.
Hao JJ, Fang XL, Chen YY, Meng ZJ, Dong FX, Yang XF, Chu Z, Kuai JX, Bao H
Metabolic brain disease 2025 Nov 5;40(8):306
Metabolic brain disease 2025 Nov 5;40(8):306
Hepatocyte growth factor alleviates alcoholic cardiomyopathy through the Nrf2 pathway-a focus on iron metabolism.
Yu Y, Chen J, Cao K, Zhang J
Journal of thoracic disease 2025 Nov 30;17(11):10149-10162
Journal of thoracic disease 2025 Nov 30;17(11):10149-10162
SLC11A2 affects nutritional immunity in the gut epithelium.
Norberg ES, Westerman TL, Cruz E, Bushman SD, Skaar EP, Elfenbein JR, Knodler LA
bioRxiv : the preprint server for biology 2025 Nov 12;
bioRxiv : the preprint server for biology 2025 Nov 12;
Targeting PIM1 by Bruceine D attenuates skin fibrosis via myofibroblast ferroptosis.
Wang J, Song Y, Tan X, Wang T, Shi Y, Xu X, Du J, Yu Z, Song B
Redox biology 2025 May;82:103619
Redox biology 2025 May;82:103619
The ferroptosis of sertoli cells inducing blood-testis barrier damage is produced by oxidative stress in cryptorchidism.
Zeng J, Yuan L, Chen G, Qi Y, Qie X, Jin Y, Chen Y, Li H
Free radical biology & medicine 2025 May;232:97-106
Free radical biology & medicine 2025 May;232:97-106
Heterogeneity of fibroblasts from different anatomical sites in healthy human knee ligaments revealed by single-cell RNA sequencing.
Zhao H, Yao Y, Jiang F, Zhu X, Yu T, Xiao X
Genomics 2025 May;117(3):111040
Genomics 2025 May;117(3):111040
Infectious Spleen and Kidney Necrosis Virus Triggers Ferroptosis in CPB Cells to Enhance Virus Replication.
Zhang Q, Chang O, Lin Q, Liang H, Niu Y, Luo X, Ma B, Li N, Fu X
Viruses 2025 May 16;17(5)
Viruses 2025 May 16;17(5)
Inhibition of Phosphodiesterase 4 Suppresses Neuronal Ferroptosis After Cerebral Ischemia/Reperfusion.
Chen K, Xu B, Long L, Wen H, Zhao Q, Tu X, Wang J, Xu J, Wang H
Molecular neurobiology 2025 Mar;62(3):3376-3395
Molecular neurobiology 2025 Mar;62(3):3376-3395
The molecular mechanism by which CTSB degrades FPN to disrupt macrophage iron homeostasis and promote the progression of atherosclerosis.
Qiu Q, Sun Q, Yang J, Yuan Q, Wang P, Liu Q, Cui Z, Ma X, Li M
Molecular and cellular biochemistry 2025 Jun;480(6):3889-3906
Molecular and cellular biochemistry 2025 Jun;480(6):3889-3906
5-HT(7)R Deficiency Alleviates ADP-Heptose-Induced Cognitive Impairment via Inhibiting Ferroptosis and Neuroinflammation in Mice.
Zou X, Yang YX, Yue BJ, Yang HY, Yang YR, Li MY, Du O, Qiao G, Wu YJ, Du JR, Long FY
CNS neuroscience & therapeutics 2025 Jun;31(6):e70455
CNS neuroscience & therapeutics 2025 Jun;31(6):e70455
OTUB1-SLC7A11 Axis Mediates 4-Octyl Itaconate Protection Against Acetaminophen-Induced Ferroptotic Liver Injury.
Hu Z, Li Y, Xu D, Meng H, Liu W, Xu Q, Yao B, Wang J
Antioxidants (Basel, Switzerland) 2025 Jun 9;14(6)
Antioxidants (Basel, Switzerland) 2025 Jun 9;14(6)
Sevoflurane exposure triggers ferroptosis of neuronal cells initiated by the activation of ATM/p53 in the neonatal mouse brain via JNK/p38 MAPK-mediated oxidative DNA damage.
Gu W, Pan T, Wang X, Kang L, Liu N, Piao M, Feng C
International immunopharmacology 2025 Jun 17;158:114866
International immunopharmacology 2025 Jun 17;158:114866
Eburicoic acid inhibits endothelial cell pyroptosis and retards the development of atherosclerosis through the Keap1/Nrf2/HO‑1/ROS pathway.
Ma MQ, Yang C, Jin SY, Yang Y, Pan YY, Lin XH
Molecular medicine reports 2025 Jul;32(1)
Molecular medicine reports 2025 Jul;32(1)
Metabolism and Mendelian randomization study on the mechanism of Buyang Huanwu Decoction in regulating iron metabolism and improving cerebral ischemia-reperfusion injury.
Xiong T, Bai Y, Shi Y, Li Y, Hu Z, Duan J, Lan X, Ding H, Zhang W
Journal of ethnopharmacology 2025 Jul 24;351:120062
Journal of ethnopharmacology 2025 Jul 24;351:120062
(+)-JQ-1 alleviates cardiac injury in myocardial infarction by inhibiting ferroptosis through the NAMPT/SIRT1 pathway.
Yang M, Wang T, Shao J, Ran X, Xiao R, Zhao R, Wu C, Ji M, Tian W, Sun H, Liu J, Zuo S
Cell death & disease 2025 Jul 23;16(1):548
Cell death & disease 2025 Jul 23;16(1):548
Low doses of ozone alleviate cardiomyocyte ferroptosis induced by hypoxia-reoxygenation injury via the AMPK-mTOR pathway.
Ding Y, Hong T
European journal of medical research 2025 Jul 2;30(1):558
European journal of medical research 2025 Jul 2;30(1):558
Viruses hijack FPN1 to disrupt iron withholding and suppress host defense.
Tong L, Wang J, Ma Y, Wang C, Fu Y, Li Q, Gao C, Song H, Qin Y, Zhao C, Zhao W
Nature communications 2025 Jul 1;16(1):5912
Nature communications 2025 Jul 1;16(1):5912
ACSS2 protects against alcohol-induced hepatocyte ferroptosis through regulation of hepcidin expression.
Wang M, Wen X, Feng Z, Choubey M, Chen S, Pan R, Gong K, Tirumalasetty MB, Gao F, Liao C, Yin Z, Zhang S, He Y, Chen H, Cao Y, Miao QR, Hu W, Duan Y
Nature communications 2025 Jul 1;16(1):5491
Nature communications 2025 Jul 1;16(1):5491
Moderate static magnetic field regulates iron metabolism and salvage bone loss caused by iron accumulation.
Zhen C, Wang S, Yang J, Zhang G, Cai C, Wang J, Wang A, Xu Y, Fang Y, Wei M, Yin D, Luo X, Gong M, Zhang H, Shang P
Journal of orthopaedic translation 2025 Jan;50:144-157
Journal of orthopaedic translation 2025 Jan;50:144-157
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis.
Qiu C, Cheng L, Di D, Xiang Z, Wang C, Li J, Xiong Y, Li M, Liu J, Zhou J, Liu T, Wang X, Luo D, Wang X, Li S, Wang H, Wang X, Zhao Y, Liu X, Wang L
Genes & diseases 2025 Jan;12(1):101251
Genes & diseases 2025 Jan;12(1):101251
Prolonged tamoxifen treatment induces iron deposition and ferroptosis in the liver.
Yang J, Wang D, Wang W, Wu C, Li C, Shi W, Qian J, Xie F, Shen H, Tang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jan 15;39(1):e70313
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jan 15;39(1):e70313
Testosterone deficiency aggravates diet-induced non-alcoholic fatty liver disease by inducing hepatocyte ferroptosis via targeting BMAL1 in mice.
Fan Y, Ren Y, Deng L, Lv D, Chen J, Ling Y, Tu J, Xu X, Wang D, Cai Z
International immunopharmacology 2025 Jan 10;144:113641
International immunopharmacology 2025 Jan 10;144:113641
The GPR30-Mediated BMP-6/HEP/FPN Signaling Pathway Inhibits Ferroptosis in Bone Marrow Mesenchymal Stem Cells to Alleviate Osteoporosis.
Chen S, Xiao J, Zhou S, Wumiti T, Zhao Z, Zhao R, Pan Y, Wang Q, Ma Y, Wu L, Guo Y
International journal of molecular sciences 2025 Feb 26;26(5)
International journal of molecular sciences 2025 Feb 26;26(5)
Targeted temperature management alleviates post-resuscitation myocardial dysfunction by inhibiting ferroptosis.
Zhang Y, Du W, Kong T, Hua T, Ma H, Hu Y, Pan S, Ling B, Yang M, Cheng C
Cell death discovery 2025 Feb 21;11(1):71
Cell death discovery 2025 Feb 21;11(1):71
Metallothionein 2A alleviates ulcerative colitis by inhibiting ferroptosis in intestinal epithelial cells with Tfrc downregulation.
Hua S, Song S, Yang C, Xu J, Li Z, Zhu B, Hua Z
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Dec;92:127746
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Dec;92:127746
The phytochemical arbutin exerts potent anti-Toxoplasma effects through activation of cell-autonomous defense mechanisms while attenuating inflammation.
Liu Z, Ma Y, Xiang Y, Shen Y, Liao L, Zhu X, Shi Z, Wei Y, Kou Y, Wang Y
PLoS neglected tropical diseases 2025 Dec;19(12):e0013815
PLoS neglected tropical diseases 2025 Dec;19(12):e0013815
Fer-1 alleviates traumatic brain injury-induced cognitive impairment by inhibiting hippocampal ferroptosis.
Kuai JX, Hao JJ, Meng ZJ, Dong FX, Chen YY, Yang XF, Chu Z, Bao HJ
IBRO neuroscience reports 2025 Dec;19:821-830
IBRO neuroscience reports 2025 Dec;19:821-830
Nicotinamide Mononucleotide Alleviates the Development of Fibrotic Cataract by Modulating the Nrf2/FPN1 Signaling Pathway.
Bao X, Pan Y, Xu Y, Xing Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 31;39(24):e71348
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 31;39(24):e71348
Deciphering the molecular landscape of NMDAR-E associated ovarian teratomas: a Multi-Omics approach.
Ma L, Sun X, Zhang S, Xiao Y, Guan H, Wang R, Tang Z, Zhang W, Xia H
Journal of ovarian research 2025 Dec 3;18(1):289
Journal of ovarian research 2025 Dec 3;18(1):289
Adipocytes orchestrate obesity-related chronic inflammation through β2-microglobulin.
Li J, Li Y, Zhou X, Yang S, Liu D, Wen H, Chen X, Duan C, Yu M, Zhang M, Tang B, Wang Y, Wang L, Wu Y
Signal transduction and targeted therapy 2025 Dec 3;10(1):394
Signal transduction and targeted therapy 2025 Dec 3;10(1):394
Toxoplasma gondii-induced ferroptosis contributes to acute lung injury in mice.
Yuan X, Liu Z, Ma Y, Liu F, Bao P, Du B, Zhang X, Gong P, Zhang N, Li J, Li X, Wang X
Parasites & vectors 2025 Dec 28;19(1):55
Parasites & vectors 2025 Dec 28;19(1):55
Nicotinamide riboside alleviates sepsis-induced acute kidney injury by suppressing ferroptosis.
Fan S, Ma X, Ren T, Guo M, Wang X, Si M
Journal of molecular medicine (Berlin, Germany) 2025 Dec 20;104(1):10
Journal of molecular medicine (Berlin, Germany) 2025 Dec 20;104(1):10
Baicalein attenuates metabolic dysfunction-associated steatohepatitis by regulating macrophage ferroptosis through nuclear factor (erythroid-derived 2)-like 2 pathway.
Wang Y, Zhao Y, Zhao W, Chen H, Cao Z, Li H, Tang Y, Zhu X, Yao P
Free radical biology & medicine 2025 Dec 1;240:238-252
Free radical biology & medicine 2025 Dec 1;240:238-252
Ferroptosis contributed to endoplasmic reticulum stress in preterm birth by targeting LHX1 and IRE-1.
Qiu L, Liu H, Chen S, Wu Y, Yan J
Cellular signalling 2025 Aug;132:111777
Cellular signalling 2025 Aug;132:111777
Trimethylamine N-oxide Induced Chronic Kidney Injury by Triggering PANoptosis.
Shao D, Bai L, Chen Q, Chen Y, Qiu Z, Liu Y, Jin S, Wu Y, Dai J
Physiological research 2025 Aug 31;74(4):613-622
Physiological research 2025 Aug 31;74(4):613-622
Effect of Self-Assembled Polydopamine Nanoparticles on Ferroptosis in an MPTP-Induced Parkinson's Disease Mice Model.
Xu Q, Xie D, Qie X, Chi B, Liu H
ACS applied bio materials 2025 Aug 18;8(8):7410-7419
ACS applied bio materials 2025 Aug 18;8(8):7410-7419
Quercetin alleviates LPS/iE-DAP-induced liver injury by suppressing ferroptosis via regulating ferritinophagy and intracellular iron efflux.
Zhang H, Shi H, Li X, Zhou S, Song X, Ma N, Meng M, Chang G, Shen X
Redox biology 2025 Apr;81:103557
Redox biology 2025 Apr;81:103557
Stress-mediated Activation of Ferroptosis, Pyroptosis, and Apoptosis Following Mild Traumatic Brain Injury Exacerbates Neurological Dysfunctions.
Zheng L, Pang Q, Huang R, Xu H, Guo H, Gao C, Chen X, Wang Y, Cao Q, Gao Y, Gu Z, Wang Z, Luo C, Tao L, Wang T
Molecular neurobiology 2025 Apr;62(4):4055-4075
Molecular neurobiology 2025 Apr;62(4):4055-4075
Targeted sonodynamic therapy induces tumor cell quasi-immunogenic ferroptosis and macrophage immunostimulatory autophagy in glioblastoma.
Wang MF, Guo J, Yuan SJ, Li K, Zhang Q, Lei HM, Wu JL, Zhao L, Xu YH, Chen X
Biomaterials 2025 Apr;315:122913
Biomaterials 2025 Apr;315:122913
Amino-modified IONPs potentiates ferroptotic cell death due to the release of Fe ion in the lysosome.
Qi Z, Huang X, Jing J, Feng W, Xu M, Yan L, Gao M, Liu S, Yu XF
Journal of environmental sciences (China) 2025 Apr;150:1-13
Journal of environmental sciences (China) 2025 Apr;150:1-13
Dapagliflozin alleviates high-fat-induced obesity cardiomyopathy by inhibiting ferroptosis.
Chen D, Shi J, Wu Y, Miao L, Wang Z, Wang Y, Xu S, Lou Y
ESC heart failure 2025 Apr;12(2):1358-1373
ESC heart failure 2025 Apr;12(2):1358-1373
Short-term effects of subacute ruminal acidosis on ferroptosis and iron metabolism in the livers of lactating sheep fed a high-grain diet.
Zhang H, Shi H, Zhou S, Meng M, Ma N, Chang G, Shen X
Journal of dairy science 2025 Apr;108(4):4365-4380
Journal of dairy science 2025 Apr;108(4):4365-4380
Integrative insights into the role of CAV1 in ketogenic diet and ferroptosis in pancreatic cancer.
Liang X, Tian R, Li T, Wang H, Qin Y, Qian M, Fan J, Wang D, Cui HY, Jiang J
Cell death discovery 2025 Apr 4;11(1):139
Cell death discovery 2025 Apr 4;11(1):139
Saponins from Astragalus membranaceus (Fisch.) Bge Alleviated Neuronal Ferroptosis in Alzheimer's Disease by Regulating the NOX4/Nrf2 Signaling Pathway.
Wang M, Li M, Jiang Y, Wang S, Yang X, Naseem A, Algradi AM, Hao Z, Guan W, Chen Q, Zhang L, Kuang H, Yang B, Liu Y
Journal of agricultural and food chemistry 2025 Apr 2;73(13):7725-7740
Journal of agricultural and food chemistry 2025 Apr 2;73(13):7725-7740
Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis.
Zhou Y, Yang Y, Yi L, Pan M, Tang W, Duan H
Drug design, development and therapy 2024;18:1349-1368
Drug design, development and therapy 2024;18:1349-1368
Progressive iron overload in middle-aged mice impairs olfactory function, triggers lipid oxidation and induces apoptosis.
Deng L, Luo Q, Liu Y, Wang Y, Xiong Z, Wang H, Zhao L, Jia L, Shi R, Huang C, Chen Z
Frontiers in pharmacology 2024;15:1506944
Frontiers in pharmacology 2024;15:1506944
Effect of ferric citrate on hippocampal iron accumulation and widespread molecular alterations associated with cognitive disorder in an ovariectomized mice model.
Cui L, Zhou H, Hao Y, Yang X, Li Z, Gao Y, Zhang Z, Ren L, Ji L, Sun R, Wang Y, Wang X
CNS neuroscience & therapeutics 2024 Sep;30(9):e70018
CNS neuroscience & therapeutics 2024 Sep;30(9):e70018
Daphnetin induces ferroptosis in ovarian cancer by inhibiting NAD(P)H:Quinone oxidoreductase 1 (NQO1).
Ma N, Zhang M, Hu J, Wei Z, Zhang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155876
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155876
MMP9 drives ferroptosis by regulating GPX4 and iron signaling.
Gawargi FI, Mishra PK
iScience 2024 Sep 20;27(9):110622
iScience 2024 Sep 20;27(9):110622
Ellagic acid ameliorates arsenic-induced neuronal ferroptosis and cognitive impairment via Nrf2/GPX4 signaling pathway.
Yang X, Chu F, Jiao Z, Yu H, Yang W, Li Y, Lu C, Ma H, Wang S, Liu Z, Qin S, Sun H
Ecotoxicology and environmental safety 2024 Sep 15;283:116833
Ecotoxicology and environmental safety 2024 Sep 15;283:116833
The hepcidin-ferroportin axis influences mitochondrial function, proliferation, and migration in pulmonary artery endothelial and smooth muscle cells.
Issitt T, Toe QK, Pedersen SL, Shackshaft T, Ghazaly MM, West L, Arnold ND, Mahomed A, Kagugube GW, Ramakrishnan L, Lawrie A, Quinlan GJ, Wort SJ
Pulmonary circulation 2024 Oct;14(4):e70006
Pulmonary circulation 2024 Oct;14(4):e70006
DHA and EPA alleviate depressive-like behaviors in chronic sleep-deprived mice: Involvement of iron metabolism, oligodendrocyte-lipids peroxidation and the LCN2-NLRP3 signaling axis.
Chen L, Yang Y, Zhang N, Che H, Wang Z, Han J, Wen M
Free radical biology & medicine 2024 Nov 20;225:654-664
Free radical biology & medicine 2024 Nov 20;225:654-664
Trimethylamine Induced Chronic Kidney Injury by Activating the ZBP1-NLRP3 Inflammasome Pathway.
Bai L, Chen Q, Li Y, Wu F, Jin M, Chen Y, Teng X, Jin S, Fan H, Wu Y
Physiological research 2024 Nov 15;73(5):779-789
Physiological research 2024 Nov 15;73(5):779-789
Water extract of moschus alleviates erastin-induced ferroptosis by regulating the Keap1/Nrf2 pathway in HT22 cells.
Song C, Chu Z, Dai J, Xie D, Qin T, Xie L, Zhai Z, Huang S, Xu Y, Sun T
Journal of ethnopharmacology 2024 May 23;326:117937
Journal of ethnopharmacology 2024 May 23;326:117937
Therapeutic potential and mechanisms of Rifaximin in ameliorating iron overload-induced ferroptosis and liver fibrosis in vivo and in vitro.
Yuan Q, Fang Y, Guo J, Zhang Z, Liao J, Kuang J
Toxicology and applied pharmacology 2024 Mar;484:116845
Toxicology and applied pharmacology 2024 Mar;484:116845
Mitochondrial ferritin alleviates ferroptosis in a kainic acid-induced mouse epilepsy model by regulating iron homeostasis: Involvement of nuclear factor erythroid 2-related factor 2.
Song Y, Gao M, Wei B, Huang X, Yang Z, Zou J, Guo Y
CNS neuroscience & therapeutics 2024 Mar;30(3):e14663
CNS neuroscience & therapeutics 2024 Mar;30(3):e14663
Hinokitiol protects gastric injury from ethanol exposure via its iron sequestration capacity.
Zhao M, Qiao C, Yang S, Tang Y, Sun W, Sun S, Guo Q, Du F, Zhang N, Ning T, Wu J, Xu J, Li P
European journal of pharmacology 2024 Mar 5;966:176340
European journal of pharmacology 2024 Mar 5;966:176340
Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx.
Xiang Z, Zhang P, Jia C, Xu R, Cao D, Xu Z, Lu T, Liu J, Wang X, Qiu C, Fu W, Li W, Cheng L, Yang Q, Feng S, Wang L, Zhao Y, Liu X
Bone research 2024 Mar 29;12(1):20
Bone research 2024 Mar 29;12(1):20
Effects of chronic low-level lead (Pb) exposure on cognitive function and hippocampal neuronal ferroptosis: An integrative approach using bioinformatics analysis, machine learning, and experimental validation.
Cao Y, Zhao W, Zhong Y, Jiang X, Mei H, Chang Y, Wu D, Dou J, Vasquez E, Shi X, Yang J, Jia Z, Tan X, Li Q, Dong Y, Xie R, Gao J, Wu Y, Liu Y
The Science of the total environment 2024 Mar 20;917:170317
The Science of the total environment 2024 Mar 20;917:170317
NCOA4-mediated ferritinophagy participates in cadmium-triggered ferroptosis in spermatogonia.
Jia D, Zhang M, Li M, Gong W, Huang W, Wang R, Chen Y, Yin Q, Wu J, Jin Z, Wang J, Liu Y, Liang C, Ji Y
Toxicology 2024 Jun;505:153831
Toxicology 2024 Jun;505:153831
Nicorandil Regulates Ferroptosis and Mitigates Septic Cardiomyopathy via TLR4/SLC7A11 Signaling Pathway.
Lu JS, Wang JH, Han K, Li N
Inflammation 2024 Jun;47(3):975-988
Inflammation 2024 Jun;47(3):975-988
YTHDF2 Promotes Cardiac Ferroptosis via Degradation of SLC7A11 in Cardiac Ischemia-Reperfusion Injury.
Pang P, Si W, Wu H, Ju J, Liu K, Wang C, Jia Y, Diao H, Zeng L, Jiang W, Yang Y, Xiong Y, Kong X, Zhang Z, Zhang F, Song J, Wang N, Yang B, Bian Y
Antioxidants & redox signaling 2024 Jun;40(16-18):889-905
Antioxidants & redox signaling 2024 Jun;40(16-18):889-905
Mitochondrial GCN5L1 acts as a novel regulator for iron homeostasis to promote sorafenib sensitivity in hepatocellular carcinoma.
Hu X, Zhang P, Li S, Zhang J, Wang D, Wang Z, Zhu L, Wang L
Journal of translational medicine 2024 Jun 25;22(1):593
Journal of translational medicine 2024 Jun 25;22(1):593
Rocaglamide regulates iron homeostasis by suppressing hepcidin expression.
Zhu X, Zuo Q, Xie X, Chen Z, Wang L, Chang L, Liu Y, Luo J, Fang C, Che L, Zhou X, Yao C, Gong C, Hu D, Zhao W, Zhou Y, Zhu S
Free radical biology & medicine 2024 Jul;219:153-162
Free radical biology & medicine 2024 Jul;219:153-162
Targeting PKD2 aggravates ferritinophagy-mediated ferroptosis via promoting autophagosome-lysosome fusion and enhances efficacy of carboplatin in lung adenocarcinoma.
Liu Y, Pang Z, Wang Y, Liu J, Wang G, Du J
Chemico-biological interactions 2024 Jan 5;387:110794
Chemico-biological interactions 2024 Jan 5;387:110794
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
Liu Y, Luo X, Chen Y, Dang J, Zeng D, Guo X, Weng W, Zhao J, Shi X, Chen J, Dong B, Zhong S, Ren J, Li Y, Wang J, Zhang J, Sun J, Xu H, Lu Y, Brand D, Zheng SG, Pan Y
Redox biology 2024 Feb;69:103008
Redox biology 2024 Feb;69:103008
Gemfibrozil Alleviates Cognitive Impairment by Inhibiting Ferroptosis of Astrocytes via Restoring the Iron Metabolism and Promoting Antioxidant Capacity in Type 2 Diabetes.
Wang N, Zhao Y, Wu M, Li N, Yan C, Guo H, Li Q, Li Q, Wang Q
Molecular neurobiology 2024 Feb;61(2):1187-1201
Molecular neurobiology 2024 Feb;61(2):1187-1201
Identification of SLC40A1, LCN2, CREB5, and SLC7A11 as ferroptosis-related biomarkers in alopecia areata through machine learning.
Xu W, Wei D, Song X
Scientific reports 2024 Feb 15;14(1):3800
Scientific reports 2024 Feb 15;14(1):3800
Apelin deficiency exacerbates cardiac injury following infarction by accelerating cardiomyocyte ferroptosis.
Zhao Y, Liang X, Li T, Shao Z, Cao Z, Zeng Y, Yan X, Chen Q, Zhou H, Li W, Cheng G, Jiang Y, Li X, Zhang Y, Hu B
Free radical research 2024 Dec;58(12):854-867
Free radical research 2024 Dec;58(12):854-867
Exploring the underlying mechanism by transcriptome sequencing in rats with high-voltage electrical burns and the role of iron metabolism.
Hao J, Lu M, Zhao X, Li C, Ge C, Zhang J, Tu L, Zhang Q
Burns : journal of the International Society for Burn Injuries 2024 Dec;50(9):107226
Burns : journal of the International Society for Burn Injuries 2024 Dec;50(9):107226
A 0.2 T-0.4 T Static Magnetic Field Improves the Bone Quality of Mice Subjected to Hindlimb Unloading and Reloading Through the Dual Regulation of BMSCs via Iron Metabolism.
Wang J, Zhen C, Zhang G, Yang Z, Shang P
International journal of molecular sciences 2024 Dec 6;25(23)
International journal of molecular sciences 2024 Dec 6;25(23)
Investigating the potential risk of cadmium exposure on seizure severity and anxiety-like behaviors through the ferroptosis pathway in epileptic mice: An integrated multi-omics approach.
Chang Y, Jiang X, Dou J, Xie R, Zhao W, Cao Y, Gao J, Yao F, Wu D, Mei H, Zhong Y, Ge Y, Xu H, Jiang W, Xiao X, Jiang Y, Hu S, Wu Y, Liu Y
Journal of hazardous materials 2024 Dec 5;480:135814
Journal of hazardous materials 2024 Dec 5;480:135814
MCM4 potentiates evasion of hepatocellular carcinoma from sorafenib-induced ferroptosis through Nrf2 signaling pathway.
Liu X, Zhang F, Fan Y, Qiu C, Wang K
International immunopharmacology 2024 Dec 5;142(Pt A):113107
International immunopharmacology 2024 Dec 5;142(Pt A):113107
1,3-Dichloro-2-propanol Induced Renal Cell Ferroptosis via the Circadian Clock Protein BMAL1 Targeting GPX4.
Chen Y, Guan S, Liu M, Lang L, Peng H, Lu J
Journal of agricultural and food chemistry 2024 Dec 4;72(48):26859-26873
Journal of agricultural and food chemistry 2024 Dec 4;72(48):26859-26873
MoS(2) Nanosheets at Low Doses Induced Cardiotoxicity in Developing Zebrafish via Ferroptosis: Influence of Lateral Size and Surface Modification.
Zou W, Chang Y, Zhang X, Li X, Jin C, Zhang G, Cao Z, Zhou Q
Environmental science & technology 2024 Dec 24;58(51):22539-22552
Environmental science & technology 2024 Dec 24;58(51):22539-22552
Social defeat stress impairs systemic iron metabolism by activating the hepcidin-ferroportin axis.
Kasahara E, Nakamura A, Morimoto K, Ito S, Hori M, Sekiyama A
FASEB bioAdvances 2024 Aug;6(8):263-275
FASEB bioAdvances 2024 Aug;6(8):263-275
Preventive effects of lactoferrin on acute alcohol-induced liver injury via iron chelation and regulation of iron metabolism.
Guan S, Zhang S, Liu M, Guo J, Chen Y, Shen X, Deng X, Lu J
Journal of dairy science 2024 Aug;107(8):5316-5329
Journal of dairy science 2024 Aug;107(8):5316-5329
Hepcidin depending on astrocytic NEO1 ameliorates blood-brain barrier dysfunction after subarachnoid hemorrhage.
Wei B, Liu W, Jin L, Huang Y, Cheng W, Fan H, Su S, Jin F, Zhang X, Yang Z, Liang S, Li L, Wu Y, Liu Y, Duan C, Li X
Cell death & disease 2024 Aug 7;15(8):569
Cell death & disease 2024 Aug 7;15(8):569
Magnetically attracting hydrogel reshapes iron metabolism for tissue repair.
Xu Y, Cai F, Zhou Y, Tang J, Mao J, Wang W, Li Z, Zhou L, Feng Y, Xi K, Gu Y, Chen L
Science advances 2024 Aug 16;10(33):eado7249
Science advances 2024 Aug 16;10(33):eado7249
Inhibiting DNA methyltransferase DNMT3B confers protection against ferroptosis in nucleus pulposus and ameliorates intervertebral disc degeneration via upregulating SLC40A1.
Chen J, Yang X, Li Q, Ma J, Li H, Wang L, Chen Z, Quan Z
Free radical biology & medicine 2024 Aug 1;220:139-153
Free radical biology & medicine 2024 Aug 1;220:139-153
Human umbilical cord mesenchymal stem cells alleviate chemotherapy-induced premature ovarian insufficiency mouse model by suppressing ferritinophagy-mediated ferroptosis in granulosa cells.
Dai W, Xu B, Ding L, Zhang Z, Yang H, He T, Liu L, Pei X, Fu X
Free radical biology & medicine 2024 Aug 1;220:1-14
Free radical biology & medicine 2024 Aug 1;220:1-14
Excess iron accumulation mediated senescence in diabetic kidney injury.
Cheng X, Li Y, Chen L, Jiang C, Peng S, Yao P, Tang Y
Journal of biochemical and molecular toxicology 2024 Apr;38(4):e23683
Journal of biochemical and molecular toxicology 2024 Apr;38(4):e23683
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Lai W, Yu L, Deng Y
Communications biology 2024 Apr 9;7(1):429
Communications biology 2024 Apr 9;7(1):429
Non-targeted metabolomics strategy reveals the role of Geng-Nian-Shu in regulating ferroptosis in perimenopausal syndrome.
Lv X, Bi A, Zhang Z, Li J, Wei Y, Wan M, Wang J, Yan T, Jia Y
Journal of pharmaceutical and biomedical analysis 2024 Apr 15;241:115980
Journal of pharmaceutical and biomedical analysis 2024 Apr 15;241:115980
Role of ferroptosis in hypoxic preconditioning to reduce propofol neurotoxicity.
Chen J, Xiao F, Chen L, Zhou Z, Wei Y, Zhong Y, Li L, Xie Y
Frontiers in pharmacology 2023;14:1121280
Frontiers in pharmacology 2023;14:1121280
Moderate Intensity of Treadmill Exercise Rescues TBI-Induced Ferroptosis, Neurodegeneration, and Cognitive Impairments via Suppressing STING Pathway.
Chen J, Zhu T, Yu D, Yan B, Zhang Y, Jin J, Yang Z, Zhang B, Hao X, Chen Z, Yan C, Yu J
Molecular neurobiology 2023 Sep;60(9):4872-4896
Molecular neurobiology 2023 Sep;60(9):4872-4896
Trastuzumab-induced cardiomyopathy via ferroptosis-mediated mitochondrial dysfunction.
Ye T, Yang W, Gao T, Yu X, Chen T, Yang Y, Guo J, Li Q, Li H, Yang L
Free radical biology & medicine 2023 Sep;206:143-161
Free radical biology & medicine 2023 Sep;206:143-161
PPM1K mediates metabolic disorder of branched-chain amino acid and regulates cerebral ischemia-reperfusion injury by activating ferroptosis in neurons.
Li T, Zhao L, Li Y, Dang M, Lu J, Lu Z, Huang Q, Yang Y, Feng Y, Wang X, Jian Y, Wang H, Guo Y, Zhang L, Jiang Y, Fan S, Wu S, Fan H, Kuang F, Zhang G
Cell death & disease 2023 Sep 26;14(9):634
Cell death & disease 2023 Sep 26;14(9):634
Blocked erythroid differentiation and delayed enucleation of erythroblasts may contribute to murine embryonic toxicity upon exposure to low dose of cadmium.
Wang Q, Li J, Ma W, Sun L, Zhang B, Zhao Y, Zhang S
Toxicology letters 2023 Sep 15;387:28-34
Toxicology letters 2023 Sep 15;387:28-34
Resveratrol inhibits ferroptosis via activating NRF2/GPX4 pathway in mice with spinal cord injury.
Ni C, Ye Q, Mi X, Jiao D, Zhang S, Cheng R, Fang Z, Fang M, Ye X
Microscopy research and technique 2023 Oct;86(10):1378-1390
Microscopy research and technique 2023 Oct;86(10):1378-1390
Enriched environment attenuates ferroptosis after cerebral ischemia/reperfusion injury by regulating iron metabolism.
Luo Q, Zheng J, Fan B, Liu J, Liao W, Zhang X
Brain research bulletin 2023 Oct 15;203:110778
Brain research bulletin 2023 Oct 15;203:110778
Neuroprotective Effect of Hydrogen Sulfide Subchronic Treatment Against TBI-Induced Ferroptosis and Cognitive Deficits Mediated Through Wnt Signaling Pathway.
Chen J, Chen Z, Yu D, Yan Y, Hao X, Zhang M, Zhu T
Cellular and molecular neurobiology 2023 Nov;43(8):4117-4140
Cellular and molecular neurobiology 2023 Nov;43(8):4117-4140
Hepcidin as a key regulator of iron homeostasis triggers inflammatory features in the normal endometrium.
Izumi Y, Kataoka H, Koshiba A, Ito F, Tanaka Y, Takaoka O, Maeda E, Okimura H, Sugahara T, Tarumi Y, Shimura K, Khan KN, Kusuki I, Mori T
Free radical biology & medicine 2023 Nov 20;209(Pt 2):191-201
Free radical biology & medicine 2023 Nov 20;209(Pt 2):191-201
Quercetin alleviates subarachnoid hemorrhage-induced early brain injury via inhibiting ferroptosis in the rat model.
Jiao D, Xu J, Lou C, Luo Y, Ni C, Shen G, Fang M, Gong X
Anatomical record (Hoboken, N.J. : 2007) 2023 Mar;306(3):638-650
Anatomical record (Hoboken, N.J. : 2007) 2023 Mar;306(3):638-650
Thorium(IV) triggers ferroptosis through disrupting iron homeostasis and heme metabolism in the liver following oral ingestion.
Ma M, Wang R, Xu M
Journal of hazardous materials 2023 Jun 15;452:131217
Journal of hazardous materials 2023 Jun 15;452:131217
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
Kuang H, Sun X, Liu Y, Tang M, Wei Y, Shi Y, Li R, Xiao G, Kang J, Wang F, Peng J, Xu H, Zhou F
The FEBS journal 2023 Jul;290(14):3664-3687
The FEBS journal 2023 Jul;290(14):3664-3687
ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA4.
Wu H, Liu Q, Shan X, Gao W, Chen Q
Autophagy 2023 Jul;19(7):2062-2077
Autophagy 2023 Jul;19(7):2062-2077
Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3-NFS1 axis in doxorubicin-induced cardiotoxicity.
Wang Y, Ying X, Wang Y, Zou Z, Yuan A, Xiao Z, Geng N, Qiao Z, Li W, Lu X, Pu J
Cellular signalling 2023 Jul;107:110655
Cellular signalling 2023 Jul;107:110655
Super-enhancer-driven MLX mediates redox balance maintenance via SLC7A11 in osteosarcoma.
Guo W, Wang X, Lu B, Yu J, Xu M, Huang R, Cheng M, Yang M, Zhao W, Zou C
Cell death & disease 2023 Jul 17;14(7):439
Cell death & disease 2023 Jul 17;14(7):439
cGAS-STING pathway aggravates early cerebral ischemia-reperfusion injury in mice by activating NCOA4-mediated ferritinophagy.
Li B, Wang W, Li Y, Wang S, Liu H, Xia Z, Gao W, Zhao B
Experimental neurology 2023 Jan;359:114269
Experimental neurology 2023 Jan;359:114269
TrkB agonist N-acetyl serotonin promotes functional recovery after traumatic brain injury by suppressing ferroptosis via the PI3K/Akt/Nrf2/Ferritin H pathway.
Cheng Y, Gao Y, Li J, Rui T, Li Q, Chen H, Jia B, Song Y, Gu Z, Wang T, Gao C, Wang Y, Wang Z, Wang F, Tao L, Luo C
Free radical biology & medicine 2023 Jan;194:184-198
Free radical biology & medicine 2023 Jan;194:184-198
Sphingosine 1-phosphate alleviates radiation-induced ferroptosis in ovarian granulosa cells by upregulating glutathione peroxidase 4.
Zhao J, Tang M, Tang H, Wang M, Guan H, Tang L, Zhang H
Reproductive toxicology (Elmsford, N.Y.) 2023 Jan;115:49-55
Reproductive toxicology (Elmsford, N.Y.) 2023 Jan;115:49-55
Organic extracts in PM2.5 are the major triggers to induce ferroptosis in SH-SY5Y cells.
Guo C, Lyu Y, Xia S, Ren X, Li Z, Tian F, Zheng J
Ecotoxicology and environmental safety 2023 Jan 1;249:114350
Ecotoxicology and environmental safety 2023 Jan 1;249:114350
Human hematopoietic stem cell vulnerability to ferroptosis.
Zhao J, Jia Y, Mahmut D, Deik AA, Jeanfavre S, Clish CB, Sankaran VG
Cell 2023 Feb 16;186(4):732-747.e16
Cell 2023 Feb 16;186(4):732-747.e16
Guilu-Erxian-Glue alleviates Tripterygium wilfordii polyglycoside-induced oligoasthenospermia in rats by resisting ferroptosis via the Keap1/Nrf2/GPX4 signaling pathway.
Ding J, Lu B, Liu L, Zhong Z, Wang N, Li B, Sheng W, He Q
Pharmaceutical biology 2023 Dec;61(1):213-227
Pharmaceutical biology 2023 Dec;61(1):213-227
Sculponeatin A promotes the ETS1-SYVN1 interaction to induce SLC7A11/xCT-dependent ferroptosis in breast cancer.
Peng P, Ren Y, Wan F, Tan M, Wu H, Shen J, Qian C, Liu X, Xiang Y, Yu Q, Zhang L, Si Y, Liu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Aug;117:154921
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Aug;117:154921
IRP1 mediated ferroptosis reverses temozolomide resistance in glioblastoma via affecting LCN2/FPN1 signaling axis depended on NFKB2.
Lan Y, Yang T, Yue Q, Wang Z, Zhong X, Luo X, Zuo B, Zhang M, Zeng T, Liu B, Guo H
iScience 2023 Aug 18;26(8):107377
iScience 2023 Aug 18;26(8):107377
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
Dong C, Song C, He Z, Song Q, Song T, Liu J, Xiong Y, Su X, Zhou J, Yang S, Liao W
International immunopharmacology 2023 Apr;117:110042
International immunopharmacology 2023 Apr;117:110042
Iron-frataxin involved in the protective effect of quercetin against alcohol-induced liver mitochondrial dysfunction.
Liu J, Chen H, Lin H, Peng S, Chen L, Cheng X, Yao P, Tang Y
The Journal of nutritional biochemistry 2023 Apr;114:109258
The Journal of nutritional biochemistry 2023 Apr;114:109258
Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats.
Liang Z, Miao Y, Teng X, Xiao L, Guo Q, Xue H, Tian D, Jin S, Wu Y
Frontiers in molecular biosciences 2022;9:947778
Frontiers in molecular biosciences 2022;9:947778
Low Level of Dietary Organic Trace Elements Improve the Eggshell Strength, Trace Element Utilization, and Intestinal Function in Late-Phase Laying Hens.
Chen X, Ma XM, Yang CW, Jiang SZ, Huang LB, Li Y, Zhang F, Jiao N, Yang WR
Frontiers in veterinary science 2022;9:903615
Frontiers in veterinary science 2022;9:903615
Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury.
Peng Y, Liao B, Zhou Y, Zeng W, Zeng ZY
Cardiology research and practice 2022;2022:3972829
Cardiology research and practice 2022;2022:3972829
HO-1 Contributes to Luteolin-Triggered Ferroptosis in Clear Cell Renal Cell Carcinoma via Increasing the Labile Iron Pool and Promoting Lipid Peroxidation.
Han S, Lin F, Qi Y, Liu C, Zhou L, Xia Y, Chen K, Xing J, Liu Z, Yu W, Zhang Y, Zhou X, Rao T, Cheng F
Oxidative medicine and cellular longevity 2022;2022:3846217
Oxidative medicine and cellular longevity 2022;2022:3846217
NCOA4-mediated ferritinophagy is involved in ionizing radiation-induced ferroptosis of intestinal epithelial cells.
Zhou H, Zhou YL, Mao JA, Tang LF, Xu J, Wang ZX, He Y, Li M
Redox biology 2022 Sep;55:102413
Redox biology 2022 Sep;55:102413
Inhibition of ferroptosis attenuates oligospermia in male Nrf2 knockout mice.
Han P, Wang X, Zhou T, Cheng J, Wang C, Sun F, Zhao X
Free radical biology & medicine 2022 Nov 20;193(Pt 1):421-429
Free radical biology & medicine 2022 Nov 20;193(Pt 1):421-429
Salidroside Alleviates Renal Fibrosis in SAMP8 Mice by Inhibiting Ferroptosis.
Yang S, Pei T, Wang L, Zeng Y, Li W, Yan S, Xiao W, Cheng W
Molecules (Basel, Switzerland) 2022 Nov 19;27(22)
Molecules (Basel, Switzerland) 2022 Nov 19;27(22)
The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages.
Wu J, Liu Q, Zhang X, Tan M, Li X, Liu P, Wu L, Jiao F, Lin Z, Wu X, Wang X, Zhao Y, Ren J
Cell death & disease 2022 Jul 28;13(7):653
Cell death & disease 2022 Jul 28;13(7):653
Eriodictyol ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via vitamin D receptor-mediated Nrf2 activation.
Li L, Li WJ, Zheng XR, Liu QL, Du Q, Lai YJ, Liu SQ
Molecular medicine (Cambridge, Mass.) 2022 Jan 29;28(1):11
Molecular medicine (Cambridge, Mass.) 2022 Jan 29;28(1):11
3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis.
Shao C, Liu Y, Chen Z, Qin Y, Wang X, Wang X, Yan C, Zhu HL, Zhao J, Qian Y
Cell chemical biology 2022 Jan 20;29(1):43-56.e12
Cell chemical biology 2022 Jan 20;29(1):43-56.e12
Electroacupuncture Preconditioning Reduces Oxidative Stress in the Acute Phase of Cerebral Ischemia-Reperfusion in Rats by Regulating Iron Metabolism Pathways.
Liang R, Tang Q, Song W, Zhang M, Teng L, Kang Y, Zhu L
Evidence-based complementary and alternative medicine : eCAM 2021;2021:3056963
Evidence-based complementary and alternative medicine : eCAM 2021;2021:3056963
Holo-lactoferrin: the link between ferroptosis and radiotherapy in triple-negative breast cancer.
Zhang Z, Lu M, Chen C, Tong X, Li Y, Yang K, Lv H, Xu J, Qin L
Theranostics 2021;11(7):3167-3182
Theranostics 2021;11(7):3167-3182
Deferoxamine Counteracts Cisplatin Resistance in A549 Lung Adenocarcinoma Cells by Increasing Vulnerability to Glutamine Deprivation-Induced Cell Death.
Liu WJ, Pan PY, Sun Y, Wang JB, Zhou H, Xie X, Duan ZY, Dong HY, Chen WN, Zhang LD, Wang C
Frontiers in oncology 2021;11:794735
Frontiers in oncology 2021;11:794735
N2L, a novel lipoic acid-niacin dimer, attenuates ferroptosis and decreases lipid peroxidation in HT22 cells.
Peng W, Zhu Z, Yang Y, Hou J, Lu J, Chen C, Liu F, Pi R
Brain research bulletin 2021 Sep;174:250-259
Brain research bulletin 2021 Sep;174:250-259
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Zeng L, Zhou J, Wang X, Zhang Y, Wang M, Su P
Free radical biology & medicine 2021 Nov 20;176:176-188
Free radical biology & medicine 2021 Nov 20;176:176-188
Activation of NRF2/FPN1 pathway attenuates myocardial ischemia-reperfusion injury in diabetic rats by regulating iron homeostasis and ferroptosis.
Tian H, Xiong Y, Zhang Y, Leng Y, Tao J, Li L, Qiu Z, Xia Z
Cell stress & chaperones 2021 Mar;27(2):149-164
Cell stress & chaperones 2021 Mar;27(2):149-164
Tolerable upper intake level of iron damages the liver of weaned piglets.
Ding H, Zhao Y, Yu X, Chen L, Han J, Feng J
Journal of animal physiology and animal nutrition 2021 Jul;105(4):668-677
Journal of animal physiology and animal nutrition 2021 Jul;105(4):668-677
Targeting miR-10a-5p/IL-6R axis for reducing IL-6-induced cartilage cell ferroptosis.
Bin S, Xin L, Lin Z, Jinhua Z, Rui G, Xiang Z
Experimental and molecular pathology 2021 Feb;118:104570
Experimental and molecular pathology 2021 Feb;118:104570
Tolerable upper intake level of iron damages the intestine and alters the intestinal flora in weaned piglets.
Ding H, Yu X, Chen L, Han J, Zhao Y, Feng J
Metallomics : integrated biometal science 2020 Sep 23;12(9):1356-1369
Metallomics : integrated biometal science 2020 Sep 23;12(9):1356-1369
miR-30-5p-mediated ferroptosis of trophoblasts is implicated in the pathogenesis of preeclampsia.
Zhang H, He Y, Wang JX, Chen MH, Xu JJ, Jiang MH, Feng YL, Gu YF
Redox biology 2020 Jan;29:101402
Redox biology 2020 Jan;29:101402
The Effects of the Combination of Oral Lactoferrin and Iron Injection on Iron Homestasis, Antioxidative Abilities and Cytokines Activities of Suckling Piglets.
Hu P, Zhao D, Zhao F, Wang J, Zhu W
Animals : an open access journal from MDPI 2019 Jul 11;9(7)
Animals : an open access journal from MDPI 2019 Jul 11;9(7)
Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome.
Gao W, Wang W, Liu G, Zhang J, Yang J, Deng Z
Metabolic brain disease 2019 Feb;34(1):319-329
Metabolic brain disease 2019 Feb;34(1):319-329
Iron Transport from Ferrous Bisglycinate and Ferrous Sulfate in DMT1-Knockout Human Intestinal Caco-2 Cells.
Yu X, Chen L, Ding H, Zhao Y, Feng J
Nutrients 2019 Feb 26;11(3)
Nutrients 2019 Feb 26;11(3)
Iron depletion participates in the suppression of cell proliferation induced by lipin1 overexpression.
Wang J, Wang S, Sun P, Cao F, Li H, Sun J, Peng M, Liu W, Shi P
Metallomics : integrated biometal science 2018 Sep 19;10(9):1307-1314
Metallomics : integrated biometal science 2018 Sep 19;10(9):1307-1314
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