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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Western blot [1]
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- Product number
- ABIN1881461 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Insulin Receptor (INSR) (N-Term), (AA 826-854) antibody
- Antibody type
- Polyclonal
- Antigen
- This INSR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 826-854 amino acids from the N-terminal region of human INSR.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- N-Term,AA 826-854
- Antibody clone number
- RB42484
- Vial size
- 400 μL
- Concentration
- 0.77 mg/mL
Submitted references Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant.
Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved.
Slaaby R, Schäffer L, Lautrup-Larsen I, Andersen AS, Shaw AC, Mathiasen IS, Brandt J
The Journal of biological chemistry 2006 Sep 8;281(36):25869-74
The Journal of biological chemistry 2006 Sep 8;281(36):25869-74
Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved.
Pandini G, Frasca F, Mineo R, Sciacca L, Vigneri R, Belfiore A
The Journal of biological chemistry 2002 Oct 18;277(42):39684-95
The Journal of biological chemistry 2002 Oct 18;277(42):39684-95
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- INSR Antibody (N-term) (ABIN1881461) western blot analysis in MDA-MB453 cell line lysates (35 μg/lane). This demonstrates the INSR antibody detected the INSR protein (arrow).
