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- References [15]
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- Product number
- 20433-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20433-1-AP, RRID:AB_10646469
- Product name
- INSR antibody
- Antibody type
- Polyclonal
- Description
- INSR antibody (Cat. #20433-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Intervention of Gastrodin in Type 2 Diabetes Mellitus and Its Mechanism.
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
Effects of Chronic Secondhand Smoke (SHS) Exposure on Cognitive Performance and Metabolic Pathways in the Hippocampus of Wild-Type and Human Tau Mice.
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Postnatal overfeeding induces hepatic microRNA-221 expression and impairs the PI3K/AKT pathway in adult male rats.
The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients in fish.
Systematic investigation of the pharmacological mechanism for renal protection by the leaves of Eucommia ulmoides Oliver using UPLC-Q-TOF/MS combined with network pharmacology analysis.
RNA-binding protein CUGBP1 controls the differential INSR splicing in molecular subtypes of breast cancer cells and affects cell aggressiveness.
Peroxisomal proliferator-activated receptor α-b deficiency induces the reprogramming of nutrient metabolism in zebrafish.
Angptl7 promotes insulin resistance and type 2 diabetes mellitus by multiple mechanisms including SOCS3-mediated IRS1 degradation.
Acid Loading Unmasks Glucose Homeostatic Instability in Proximal-Tubule-Targeted Insulin/Insulin-Like-Growth-Factor-1 Receptor Dual Knockout Mice.
Inhibited autophagy impairs systemic nutrient metabolism in Nile tilapia.
NaoXinTong Capsules inhibit the development of diabetic nephropathy in db/db mice.
MiR-128 regulation of glucose metabolism and cell proliferation in triple-negative breast cancer.
Di-(2-ethylhexyl) phthalate could disrupt the insulin signaling pathway in liver of SD rats and L02 cells via PPARγ.
Bai Y, Mo K, Wang G, Chen W, Zhang W, Guo Y, Sun Z
Frontiers in pharmacology 2021;12:710722
Frontiers in pharmacology 2021;12:710722
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
Lin L, Zeng L, Liu A, Yuan D, Peng Y, Zhang S, Li Y, Chen J, Xiao W, Gong Z
Nutrients 2021 Nov 17;13(11)
Nutrients 2021 Nov 17;13(11)
Effects of Chronic Secondhand Smoke (SHS) Exposure on Cognitive Performance and Metabolic Pathways in the Hippocampus of Wild-Type and Human Tau Mice.
Raber J, Perez R, Torres ERS, Krenik D, Boutros S, Patel E, Chlebowski AC, Torres ER, Perveen Z, Penn A, Paulsen DB, Bartlett MG, Jia E, Holden S, Hall R, Morré J, Wong C, Ho E, Choi J, Stevens JF, Noël A, Bobe G, Kisby G
Environmental health perspectives 2021 May;129(5):57009
Environmental health perspectives 2021 May;129(5):57009
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Wang H, Lv JJ, Zhao Y, Wei HL, Zhang TJ, Yang HJ, Chen ZN, Jiang JL
CNS neuroscience & therapeutics 2021 May 13;
CNS neuroscience & therapeutics 2021 May 13;
Postnatal overfeeding induces hepatic microRNA-221 expression and impairs the PI3K/AKT pathway in adult male rats.
Huang F, Zhu P, Wang J, Chen J, Lin W
Pediatric research 2021 Jan;89(1):143-149
Pediatric research 2021 Jan;89(1):143-149
The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients in fish.
Han SL, Liu Y, Limbu SM, Chen LQ, Zhang ML, Du ZY
Fish physiology and biochemistry 2021 Feb;47(1):173-188
Fish physiology and biochemistry 2021 Feb;47(1):173-188
Systematic investigation of the pharmacological mechanism for renal protection by the leaves of Eucommia ulmoides Oliver using UPLC-Q-TOF/MS combined with network pharmacology analysis.
Huang Q, Zhang F, Liu S, Jiang Y, Ouyang D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111735
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111735
RNA-binding protein CUGBP1 controls the differential INSR splicing in molecular subtypes of breast cancer cells and affects cell aggressiveness.
Huang G, Song C, Wang N, Qin T, Sui S, Obr A, Zeng L, Wood TL, Leroith D, Li M, Wu Y
Carcinogenesis 2020 Sep 24;41(9):1294-1305
Carcinogenesis 2020 Sep 24;41(9):1294-1305
Peroxisomal proliferator-activated receptor α-b deficiency induces the reprogramming of nutrient metabolism in zebrafish.
Li LY, Lv HB, Jiang ZY, Qiao F, Chen LQ, Zhang ML, Du ZY
The Journal of physiology 2020 Oct;598(20):4537-4553
The Journal of physiology 2020 Oct;598(20):4537-4553
Angptl7 promotes insulin resistance and type 2 diabetes mellitus by multiple mechanisms including SOCS3-mediated IRS1 degradation.
Xu T, Xu L, Meng P, Ma X, Yang X, Zhou Y, Feng M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Oct;34(10):13548-13560
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Oct;34(10):13548-13560
Acid Loading Unmasks Glucose Homeostatic Instability in Proximal-Tubule-Targeted Insulin/Insulin-Like-Growth-Factor-1 Receptor Dual Knockout Mice.
Aljaylani A, Fluitt M, Piselli A, Shepard BD, Tiwari S, Ecelbarger CM
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2020 Jul 18;54(4):682-695
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2020 Jul 18;54(4):682-695
Inhibited autophagy impairs systemic nutrient metabolism in Nile tilapia.
Han SL, Wang J, Zhang YX, Qiao F, Chen LQ, Zhang ML, Du ZY
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2019 Oct;236:110521
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2019 Oct;236:110521
NaoXinTong Capsules inhibit the development of diabetic nephropathy in db/db mice.
Yang S, Liu M, Chen Y, Ma C, Liu L, Zhao B, Wang Y, Li X, Zhu Y, Gao X, Kong D, Duan Y, Han J, Yang X
Scientific reports 2018 Jun 14;8(1):9158
Scientific reports 2018 Jun 14;8(1):9158
MiR-128 regulation of glucose metabolism and cell proliferation in triple-negative breast cancer.
Xiao M, Lou C, Xiao H, Yang Y, Cai X, Li C, Jia S, Huang Y
The British journal of surgery 2018 Jan;105(1):75-85
The British journal of surgery 2018 Jan;105(1):75-85
Di-(2-ethylhexyl) phthalate could disrupt the insulin signaling pathway in liver of SD rats and L02 cells via PPARγ.
Zhang W, Shen XY, Zhang WW, Chen H, Xu WP, Wei W
Toxicology and applied pharmacology 2017 Feb 1;316:17-26
Toxicology and applied pharmacology 2017 Feb 1;316:17-26
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The INSR antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human INSR. This antibody recognizes human antigen. The INSR antibody has been validated for the following applications: ELISA, WB analysis.
