Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- ABIN1673097 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Insulin Receptor (INSR) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to a sequence at the C-terminal of human INSR, different from the related rat and mouse sequences by two amino acids.Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Ligand-induced activation of the insulin receptor: a multi-step process involving structural changes in both the ligand and the receptor.
Prevalence of variants in candidate genes for type 2 diabetes mellitus in The Netherlands: the Rotterdam study and the Hoorn study.
Early neonatal death in mice homozygous for a null allele of the insulin receptor gene.
Ward CW, Lawrence MC
BioEssays : news and reviews in molecular, cellular and developmental biology 2009 Apr;31(4):422-34
BioEssays : news and reviews in molecular, cellular and developmental biology 2009 Apr;31(4):422-34
Prevalence of variants in candidate genes for type 2 diabetes mellitus in The Netherlands: the Rotterdam study and the Hoorn study.
Hart LM, Stolk RP, Dekker JM, Nijpels G, Grobbee DE, Heine RJ, Maassen JA
The Journal of clinical endocrinology and metabolism 1999 Mar;84(3):1002-6
The Journal of clinical endocrinology and metabolism 1999 Mar;84(3):1002-6
Early neonatal death in mice homozygous for a null allele of the insulin receptor gene.
Accili D, Drago J, Lee EJ, Johnson MD, Cool MH, Salvatore P, Asico LD, José PA, Taylor SI, Westphal H
Nature genetics 1996 Jan;12(1):106-9
Nature genetics 1996 Jan;12(1):106-9
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