Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Other assay [1]
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- Product number
- PAB8162 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB8162, RRID:AB_1707076
- Product name
- INSR (phospho Y1185) polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of INSR.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Placental insulin and insulin-like growth factor I receptors in normal and preeclamptic pregnancies.
AICAR, an activator of AMP-activated protein kinase, down-regulates the insulin receptor expression in HepG2 cells.
Human insulin receptor substrate-1 (IRS-1) polymorphism G972R causes IRS-1 to associate with the insulin receptor and inhibit receptor autophosphorylation.
Díaz E, Cárdenas M, Ariza AC, Larrea F, Halhali A
Clinical biochemistry 2005 Mar;38(3):243-7
Clinical biochemistry 2005 Mar;38(3):243-7
AICAR, an activator of AMP-activated protein kinase, down-regulates the insulin receptor expression in HepG2 cells.
Nakamaru K, Matsumoto K, Taguchi T, Suefuji M, Murata Y, Igata M, Kawashima J, Kondo T, Motoshima H, Tsuruzoe K, Miyamura N, Toyonaga T, Araki E
Biochemical and biophysical research communications 2005 Mar 11;328(2):449-54
Biochemical and biophysical research communications 2005 Mar 11;328(2):449-54
Human insulin receptor substrate-1 (IRS-1) polymorphism G972R causes IRS-1 to associate with the insulin receptor and inhibit receptor autophosphorylation.
McGettrick AJ, Feener EP, Kahn CR
The Journal of biological chemistry 2005 Feb 25;280(8):6441-6
The Journal of biological chemistry 2005 Feb 25;280(8):6441-6
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Dot blot analysis of INSR (phospho Y1185) polyclonal antibody (Cat # PAB8162) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 ug/mL.
- Validation comment
- Dot Blot (Peptide)