Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- MAB2389 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB2389, RRID:AB_10634201
- Product name
- INSR monoclonal antibody, clone MA-20
- Antibody type
- Monoclonal
- Antigen
- Native purified human INSR.
- Description
- Mouse monoclonal antibody raised against native INSR.
- Reactivity
- Human, Rat
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 100 μL
- Storage
- Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Small molecule insulin receptor activators potentiate insulin action in insulin-resistant cells.
Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.
Increased expression of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of noninsulin-dependent diabetes mellitus subjects.
Effect of monoclonal antibodies on human insulin receptor autophosphorylation, negative cooperativity, and down-regulation.
Li M, Youngren JF, Manchem VP, Kozlowski M, Zhang BB, Maddux BA, Goldfine ID
Diabetes 2001 Oct;50(10):2323-8
Diabetes 2001 Oct;50(10):2323-8
Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.
Frasca F, Pandini G, Scalia P, Sciacca L, Mineo R, Costantino A, Goldfine ID, Belfiore A, Vigneri R
Molecular and cellular biology 1999 May;19(5):3278-88
Molecular and cellular biology 1999 May;19(5):3278-88
Increased expression of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of noninsulin-dependent diabetes mellitus subjects.
Federici M, Zucaro L, Porzio O, Massoud R, Borboni P, Lauro D, Sesti G
The Journal of clinical investigation 1996 Dec 15;98(12):2887-93
The Journal of clinical investigation 1996 Dec 15;98(12):2887-93
Effect of monoclonal antibodies on human insulin receptor autophosphorylation, negative cooperativity, and down-regulation.
Forsayeth JR, Montemurro A, Maddux BA, DePirro R, Goldfine ID
The Journal of biological chemistry 1987 Mar 25;262(9):4134-40
The Journal of biological chemistry 1987 Mar 25;262(9):4134-40
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