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Functional assayAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Product number
- ABIN1106087 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Insulin Receptor (INSR) (Chain alpha) antibody
- Antibody type
- Monoclonal
- Antigen
- Other
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 47-9
- Vial size
- 0.1 mg
Submitted references A region of the insulin receptor important for ligand binding (residues 450-601) is recognized by patients' autoimmune antibodies and inhibitory monoclonal antibodies.
Identification of epitopes on the human insulin receptor reacting with rabbit polyclonal antisera and mouse monoclonal antibodies.
Immunological relationships between receptors for insulin and insulin-like growth factor I. Evidence for structural heterogeneity of insulin-like growth factor I receptors involving hybrids with insulin receptors.
Monoclonal antibodies to the insulin receptor mimic metabolic effects of insulin but do not stimulate receptor autophosphorylation in transfected NIH 3T3 fibroblasts.
Insulin-like and insulin-inhibitory effects of monoclonal antibodies for different epitopes on the human insulin receptor.
Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor.
Zhang B, Roth RA
Proceedings of the National Academy of Sciences of the United States of America 1991 Nov 1;88(21):9858-62
Proceedings of the National Academy of Sciences of the United States of America 1991 Nov 1;88(21):9858-62
Identification of epitopes on the human insulin receptor reacting with rabbit polyclonal antisera and mouse monoclonal antibodies.
Prigent SA, Stanley KK, Siddle K
The Journal of biological chemistry 1990 Jun 15;265(17):9970-7
The Journal of biological chemistry 1990 Jun 15;265(17):9970-7
Immunological relationships between receptors for insulin and insulin-like growth factor I. Evidence for structural heterogeneity of insulin-like growth factor I receptors involving hybrids with insulin receptors.
Soos MA, Siddle K
The Biochemical journal 1989 Oct 15;263(2):553-63
The Biochemical journal 1989 Oct 15;263(2):553-63
Monoclonal antibodies to the insulin receptor mimic metabolic effects of insulin but do not stimulate receptor autophosphorylation in transfected NIH 3T3 fibroblasts.
Soos MA, O'Brien RM, Brindle NP, Stigter JM, Okamoto AK, Whittaker J, Siddle K
Proceedings of the National Academy of Sciences of the United States of America 1989 Jul;86(14):5217-21
Proceedings of the National Academy of Sciences of the United States of America 1989 Jul;86(14):5217-21
Insulin-like and insulin-inhibitory effects of monoclonal antibodies for different epitopes on the human insulin receptor.
Taylor R, Soos MA, Wells A, Argyraki M, Siddle K
The Biochemical journal 1987 Feb 15;242(1):123-9
The Biochemical journal 1987 Feb 15;242(1):123-9
Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor.
Soos MA, Siddle K, Baron MD, Heward JM, Luzio JP, Bellatin J, Lennox ES
The Biochemical journal 1986 Apr 1;235(1):199-208
The Biochemical journal 1986 Apr 1;235(1):199-208
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