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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- HPA037850 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA037850, RRID:AB_10696358
- Product name
- Anti-HORMAD1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human HORMAD1, Gene description: HORMA domain containing 1, Alternative Gene Names: CT46, DKFZP434A1315, Validated applications: IHC, Uniprot ID: Q86X24, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references A novel bioinformatic approach reveals cooperation between Cancer/Testis genes in basal-like breast tumors
The cancer testes antigen, HORMAD1, limits genomic instability in cancer cells by protecting stalled replication forks
HORMAD1 overexpression predicts response to anthracycline–cyclophosphamide and survival in triple‐negative breast cancers
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance
Epigenetic activation of HORMAD1 in basal-like breast cancer: role in Rucaparib sensitivity
HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress
Profiling cancer testis antigens in non–small-cell lung cancer
Genomic Complexity Profiling Reveals That HORMAD1 Overexpression Contributes to Homologous Recombination Deficiency in Triple-Negative Breast Cancers
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells
Laisné M, Rodgers B, Benlamara S, Wicinski J, Nicolas A, Djerroudi L, Gupta N, Ferry L, Kirsh O, Daher D, Philippe C, Okada Y, Charafe-Jauffret E, Cristofari G, Meseure D, Vincent-Salomon A, Ginestier C, Defossez P
Oncogene 2024;43(18):1369-1385
Oncogene 2024;43(18):1369-1385
The cancer testes antigen, HORMAD1, limits genomic instability in cancer cells by protecting stalled replication forks
Herrera L, Johnson R, McGlynn K, Gibbs Z, Davis A, Whitehurst A
Journal of Biological Chemistry 2023;299(11):105348
Journal of Biological Chemistry 2023;299(11):105348
HORMAD1 overexpression predicts response to anthracycline–cyclophosphamide and survival in triple‐negative breast cancers
El‐Botty R, Vacher S, Mainguené J, Briaux A, Ibadioune S, Dahmani A, Montaudon E, Nemati F, Huguet L, Sourd L, Morriset L, Château‐Joubert S, Dubois T, Maire V, Lidereau R, Rapinat A, Gentien D, Coussy F, Bièche I, Marangoni E
Molecular Oncology 2023;17(10):2017-2028
Molecular Oncology 2023;17(10):2017-2028
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance
Zong B, Sun L, Peng Y, Wang Y, Yu Y, Lei J, Zhang Y, Guo S, Li K, Liu S
Oncology Reports 2021;46(1)
Oncology Reports 2021;46(1)
Epigenetic activation of HORMAD1 in basal-like breast cancer: role in Rucaparib sensitivity
Wang X, Tan Y, Cao X, Kim J, Chen T, Hu Y, Wexler M, Wang X
Oncotarget 2018;9(53):30115-30127
Oncotarget 2018;9(53):30115-30127
HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress
Nichols B, Oswald N, McMillan E, McGlynn K, Yan J, Kim M, Saha J, Mallipeddi P, LaDuke S, Villalobos P, Rodriguez-Canales J, Wistuba I, Posner B, Davis A, Minna J, MacMillan J, Whitehurst A
Cancer Research 2018;78(21):6196-6208
Cancer Research 2018;78(21):6196-6208
Profiling cancer testis antigens in non–small-cell lung cancer
Djureinovic D, Hallström B, Horie M, Mattsson J, La Fleur L, Fagerberg L, Brunnström H, Lindskog C, Madjar K, Rahnenführer J, Ekman S, Ståhle E, Koyi H, Brandén E, Edlund K, Hengstler J, Lambe M, Saito A, Botling J, Pontén F, Uhlén M, Micke P
JCI Insight 2016;1(10)
JCI Insight 2016;1(10)
Genomic Complexity Profiling Reveals That HORMAD1 Overexpression Contributes to Homologous Recombination Deficiency in Triple-Negative Breast Cancers
Watkins J, Weekes D, Shah V, Gazinska P, Joshi S, Sidhu B, Gillett C, Pinder S, Vanoli F, Jasin M, Mayrhofer M, Isaksson A, Cheang M, Mirza H, Frankum J, Lord C, Ashworth A, Vinayak S, Ford J, Telli M, Grigoriadis A, Tutt A
Cancer Discovery 2015;5(5):488-505
Cancer Discovery 2015;5(5):488-505
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells
Stadler C, Rexhepaj E, Singan V, Murphy R, Pepperkok R, Uhlén M, Simpson J, Lundberg E
Nature Methods 2013;10(4):315-323
Nature Methods 2013;10(4):315-323
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human testis and cerebral cortex tissues using HPA037850 antibody. Corresponding HORMAD1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
